IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Sgk2

serum/glucocorticoid regulated kinase 2

RGD: 620232
Ensembl: ENSRNOG00000033573
Entrez: 171497
UniProtKB: Q8R4U9

Process Predictions
Disease Predictions

Sgk2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transmembrane transport	GO:0098655	263	0.195	Human
response to nutrient levels	GO:0031667	370	0.174
single organism catabolic process	GO:0044712	283	0.132
response to acid chemical	GO:0001101	222	0.129
cellular response to oxygen containing compound	GO:1901701	386	0.117	Rat
cellular response to endogenous stimulus	GO:0071495	377	0.109	Rat
small molecule biosynthetic process	GO:0044283	124	0.108
organic substance catabolic process	GO:1901575	316	0.106
ion transmembrane transport	GO:0034220	365	0.097	Human
response to carbohydrate	GO:0009743	183	0.096
organic acid metabolic process	GO:0006082	292	0.087
response to extracellular stimulus	GO:0009991	380	0.087
membrane organization	GO:0061024	94	0.083	Yeast
response to metal ion	GO:0010038	253	0.081
single organism biosynthetic process	GO:0044711	342	0.078	Yeast
positive regulation of transport	GO:0051050	245	0.073	Yeast Rat
regulation of anatomical structure size	GO:0090066	135	0.072	Yeast
carboxylic acid transport	GO:0046942	115	0.067
response to vitamin	GO:0033273	131	0.065
anion transport	GO:0006820	178	0.065	Yeast
catabolic process	GO:0009056	351	0.064
organic acid biosynthetic process	GO:0016053	83	0.064
cellular catabolic process	GO:0044248	295	0.063
muscle cell proliferation	GO:0033002	84	0.063
regulation of ion transport	GO:0043269	245	0.063	Yeast Rat
response to nutrient	GO:0007584	248	0.062
response to toxic substance	GO:0009636	133	0.061
regulation of phagocytosis engulfment	GO:0060099	4	0.060
cellular response to organic cyclic compound	GO:0071407	202	0.053	Rat
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.053	Yeast
regulation of molecular function	GO:0065009	398	0.052
carboxylic acid metabolic process	GO:0019752	289	0.052
establishment of protein localization	GO:0045184	141	0.051
response to transition metal nanoparticle	GO:1990267	122	0.050
pyruvate metabolic process	GO:0006090	27	0.050
negative regulation of cellular component organization	GO:0051129	83	0.049	Yeast Rat
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.049	Yeast
carboxylic acid biosynthetic process	GO:0046394	83	0.049
organic acid transport	GO:0015849	116	0.048
carbohydrate metabolic process	GO:0005975	130	0.047
regulation of blood vessel size	GO:0050880	89	0.046
heterocycle catabolic process	GO:0046700	167	0.046
secretion	GO:0046903	307	0.046
nitrogen compound transport	GO:0071705	229	0.045
positive regulation of catalytic activity	GO:0043085	184	0.045
organic cyclic compound catabolic process	GO:1901361	175	0.044
cellular response to stress	GO:0033554	269	0.043	Yeast
ion homeostasis	GO:0050801	212	0.043	Rat
regulation of homeostatic process	GO:0032844	101	0.043
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.042
regulation of transmembrane transport	GO:0034762	122	0.040
intracellular signal transduction	GO:0035556	314	0.040
monocarboxylic acid metabolic process	GO:0032787	152	0.040
response to estrogen	GO:0043627	232	0.040
cofactor metabolic process	GO:0051186	95	0.039
amino acid transport	GO:0006865	70	0.039
nucleobase containing small molecule metabolic process	GO:0055086	316	0.039
aromatic compound catabolic process	GO:0019439	168	0.038
toxin catabolic process	GO:0009407	1	0.038
regulation of cell differentiation	GO:0045595	320	0.038	Rat
oxoacid metabolic process	GO:0043436	290	0.038
positive regulation of defense response	GO:0031349	37	0.038
response to glucocorticoid	GO:0051384	223	0.037	Rat
response to monosaccharide	GO:0034284	159	0.036
positive regulation of molecular function	GO:0044093	230	0.035
regulation of signal transduction	GO:0009966	318	0.035
organophosphate metabolic process	GO:0019637	370	0.035	Yeast
cellular response to peptide hormone stimulus	GO:0071375	120	0.035	Rat
negative regulation of multicellular organismal process	GO:0051241	203	0.034
cellular ketone metabolic process	GO:0042180	51	0.034
cellular amine metabolic process	GO:0044106	38	0.034
transcription dna templated	GO:0006351	377	0.034	Yeast
regulation of cellular component organization	GO:0051128	368	0.033	Yeast Rat
nucleoside phosphate catabolic process	GO:1901292	140	0.033
cellular amino acid metabolic process	GO:0006520	107	0.031
response to other organism	GO:0051707	220	0.031
positive regulation of cellular biosynthetic process	GO:0031328	295	0.030	Yeast
central nervous system development	GO:0007417	311	0.030
nucleoside triphosphate metabolic process	GO:0009141	144	0.030
cellular nitrogen compound catabolic process	GO:0044270	163	0.030
response to external biotic stimulus	GO:0043207	221	0.030
monosaccharide metabolic process	GO:0005996	61	0.029
cellular response to lipid	GO:0071396	201	0.029	Rat
regulation of response to stress	GO:0080134	126	0.029	Yeast
positive regulation of response to external stimulus	GO:0032103	51	0.029
cellular response to organonitrogen compound	GO:0071417	197	0.029	Rat
transmission of nerve impulse	GO:0019226	42	0.028
purine ribonucleotide metabolic process	GO:0009150	227	0.028
response to inorganic substance	GO:0010035	377	0.028
response to ddt	GO:0046680	1	0.028
organonitrogen compound catabolic process	GO:1901565	179	0.028
regulation of cellular catabolic process	GO:0031329	101	0.028
taxis	GO:0042330	67	0.027
cellular response to growth factor stimulus	GO:0071363	162	0.027
generation of precursor metabolites and energy	GO:0006091	62	0.027
response to estradiol	GO:0032355	164	0.027
positive regulation of locomotion	GO:0040017	102	0.027
nucleotide metabolic process	GO:0009117	279	0.027
protein localization	GO:0008104	191	0.027	Yeast Rat
carbohydrate derivative metabolic process	GO:1901135	346	0.026
cellular polysaccharide metabolic process	GO:0044264	23	0.025
regulation of system process	GO:0044057	208	0.025
cell cell signaling	GO:0007267	335	0.025
tissue development	GO:0009888	252	0.025
organic anion transport	GO:0015711	132	0.025	Yeast
single organism carbohydrate catabolic process	GO:0044724	40	0.024
brain development	GO:0007420	247	0.024
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.024
apoptotic process	GO:0006915	381	0.024	Rat
transmembrane transport	GO:0055085	412	0.024	Human
positive regulation of transcription dna templated	GO:0045893	197	0.024	Yeast
multicellular organismal signaling	GO:0035637	44	0.024
regulation of cell projection organization	GO:0031344	175	0.024	Rat
positive regulation of muscle contraction	GO:0045933	22	0.024
coenzyme metabolic process	GO:0006732	86	0.024
response to wounding	GO:0009611	254	0.023
nucleobase containing compound catabolic process	GO:0034655	152	0.023
regulation of nervous system development	GO:0051960	264	0.023	Rat
nucleoside phosphate metabolic process	GO:0006753	283	0.022
regulation of hormone secretion	GO:0046883	106	0.022
vascular process in circulatory system	GO:0003018	96	0.022
regulation of cellular protein metabolic process	GO:0032268	267	0.022
signal release	GO:0023061	145	0.022
circulatory system process	GO:0003013	183	0.022
regulation of secretion	GO:0051046	224	0.022
amide transport	GO:0042886	105	0.022
positive regulation of nucleotide metabolic process	GO:0045981	91	0.022
lipid metabolic process	GO:0006629	283	0.022	Yeast
negative regulation of cell development	GO:0010721	82	0.022
small molecule catabolic process	GO:0044282	59	0.022
regulation of muscle system process	GO:0090257	79	0.022
dephosphorylation	GO:0016311	98	0.022
regeneration	GO:0031099	163	0.021
regulation of inflammatory response	GO:0050727	48	0.021
ribonucleoside catabolic process	GO:0042454	126	0.021
locomotion	GO:0040011	237	0.021
positive regulation of phagocytosis engulfment	GO:0060100	4	0.021
cell morphogenesis	GO:0000902	142	0.021	Rat
response to retinoic acid	GO:0032526	63	0.021
protein transport	GO:0015031	132	0.021
amine metabolic process	GO:0009308	38	0.021
regulation of catalytic activity	GO:0050790	304	0.020
negative regulation of neurogenesis	GO:0050768	78	0.020
response to peptide	GO:1901652	292	0.020	Rat
regulation of transcription dna templated	GO:0006355	374	0.020	Yeast
regulation of phosphate metabolic process	GO:0019220	349	0.020
regulation of catabolic process	GO:0009894	113	0.020
chemical homeostasis	GO:0048878	292	0.020	Rat
muscle contraction	GO:0006936	88	0.020
peptide hormone secretion	GO:0030072	84	0.020
nucleotide catabolic process	GO:0009166	139	0.020
purine ribonucleoside metabolic process	GO:0046128	168	0.020
neuron projection development	GO:0031175	273	0.020	Rat
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.020
response to insulin	GO:0032868	133	0.020	Rat
positive regulation of catabolic process	GO:0009896	78	0.019
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.019
positive regulation of phosphate metabolic process	GO:0045937	262	0.019
secretion by cell	GO:0032940	248	0.019
smooth muscle cell proliferation	GO:0048659	77	0.019
negative regulation of developmental process	GO:0051093	125	0.019
neurological system process	GO:0050877	219	0.019	Rat
intracellular transport	GO:0046907	185	0.019
positive regulation of biosynthetic process	GO:0009891	319	0.018	Yeast
single organism carbohydrate metabolic process	GO:0044723	118	0.018
response to corticosteroid	GO:0031960	235	0.018	Rat
negative regulation of apoptotic process	GO:0043066	181	0.018	Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.018
energy derivation by oxidation of organic compounds	GO:0015980	46	0.018
glycogen biosynthetic process	GO:0005978	15	0.018
developmental induction	GO:0031128	2	0.018
response to starvation	GO:0042594	59	0.018
purine ribonucleotide catabolic process	GO:0009154	136	0.018
muscle system process	GO:0003012	115	0.017
negative regulation of cell differentiation	GO:0045596	99	0.017
regulation of odontogenesis of dentin containing tooth	GO:0042487	2	0.017
ribonucleoside metabolic process	GO:0009119	174	0.017
cellular response to hormone stimulus	GO:0032870	247	0.017	Rat
cellular response to nitrogen compound	GO:1901699	210	0.017	Rat
amine transport	GO:0015837	57	0.017
purine nucleotide metabolic process	GO:0006163	229	0.017
rna biosynthetic process	GO:0032774	380	0.017	Yeast
purine nucleotide catabolic process	GO:0006195	136	0.017
organophosphate catabolic process	GO:0046434	148	0.017
response to growth factor	GO:0070848	189	0.017
indolalkylamine metabolic process	GO:0006586	5	0.017
blood circulation	GO:0008015	183	0.016
regulation of smooth muscle cell proliferation	GO:0048660	75	0.016
glycogen metabolic process	GO:0005977	23	0.016
negative regulation of cell communication	GO:0010648	158	0.016
positive regulation of fat cell proliferation	GO:0070346	1	0.016
anion transmembrane transport	GO:0098656	77	0.016
negative regulation of nervous system development	GO:0051961	79	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.016
regulation of multicellular organismal development	GO:2000026	376	0.016	Rat
cellular response to external stimulus	GO:0071496	118	0.016
response to glucose	GO:0009749	136	0.016
regulation of cellular amine metabolic process	GO:0033238	8	0.016
antibiotic transport	GO:0042891	2	0.015
organ regeneration	GO:0031100	101	0.015
response to oxygen levels	GO:0070482	265	0.015
response to zinc ion	GO:0010043	39	0.015
multicellular organism growth	GO:0035264	1	0.015	Worm
regulation of hormone levels	GO:0010817	187	0.015
glutathione biosynthetic process	GO:0006750	3	0.015
nucleoside catabolic process	GO:0009164	126	0.015
negative regulation of collagen biosynthetic process	GO:0032966	4	0.015
glycosyl compound catabolic process	GO:1901658	126	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.015
regulation of secretion by cell	GO:1903530	208	0.015
rna metabolic process	GO:0016070	406	0.015	Yeast
organophosphate biosynthetic process	GO:0090407	143	0.015
ribonucleotide catabolic process	GO:0009261	136	0.015
regulation of cell motility	GO:2000145	131	0.015
reproduction	GO:0000003	245	0.015	Worm
purine containing compound catabolic process	GO:0072523	138	0.015
negative regulation of response to stimulus	GO:0048585	155	0.015
glycolytic process	GO:0006096	17	0.014
regulation of intracellular signal transduction	GO:1902531	218	0.014
macromolecule localization	GO:0033036	252	0.014	Yeast Rat Worm
insulin secretion	GO:0030073	69	0.014
cellular homeostasis	GO:0019725	252	0.014	Rat
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.014
positive regulation of amino acid transport	GO:0051957	13	0.014
immune response	GO:0006955	104	0.014
cellular polysaccharide biosynthetic process	GO:0033692	15	0.014
intracellular protein transport	GO:0006886	79	0.014
cellular macromolecule localization	GO:0070727	122	0.014
response to decreased oxygen levels	GO:0036293	237	0.014
macromolecular complex assembly	GO:0065003	273	0.014	Rat
positive regulation of cellular protein metabolic process	GO:0032270	167	0.014
cellular response to insulin stimulus	GO:0032869	81	0.014	Rat
purine nucleoside metabolic process	GO:0042278	169	0.014
positive regulation of gene expression	GO:0010628	244	0.014	Yeast
translation	GO:0006412	35	0.014
isoprenoid metabolic process	GO:0006720	45	0.014
nucleoside triphosphate catabolic process	GO:0009143	123	0.014
positive regulation of hydrolase activity	GO:0051345	86	0.014
glucan biosynthetic process	GO:0009250	15	0.014
ribonucleotide metabolic process	GO:0009259	231	0.014
cellular response to extracellular stimulus	GO:0031668	73	0.013
positive regulation of cellular catabolic process	GO:0031331	71	0.013
carbohydrate derivative catabolic process	GO:1901136	147	0.013
response to axon injury	GO:0048678	59	0.013
cell projection organization	GO:0030030	302	0.013	Rat
single organism organelle organization	GO:1902589	180	0.013	Rat
response to biotic stimulus	GO:0009607	226	0.013
response to hypoxia	GO:0001666	231	0.013
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.013	Yeast
cation transport	GO:0006812	382	0.013	Human Rat
purine ribonucleoside catabolic process	GO:0046130	124	0.013
positive regulation of organic acid transport	GO:0032892	22	0.013
polysaccharide metabolic process	GO:0005976	25	0.013
carboxylic acid catabolic process	GO:0046395	49	0.013
developmental growth involved in morphogenesis	GO:0060560	33	0.013
positive regulation of cellular amine metabolic process	GO:0033240	3	0.013
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013	Rat
regulation of neurogenesis	GO:0050767	247	0.013	Rat
monosaccharide transport	GO:0015749	31	0.013
cellular component assembly	GO:0022607	360	0.013	Yeast Rat
regulation of tube size	GO:0035150	89	0.013
regulation of transferase activity	GO:0051338	123	0.012
cellular response to steroid hormone stimulus	GO:0071383	93	0.012	Rat
regulation of locomotion	GO:0040012	148	0.012
organic hydroxy compound transport	GO:0015850	77	0.012
regulation of immune response	GO:0050776	55	0.012
cell growth	GO:0016049	104	0.012	Rat
positive regulation of nucleoside metabolic process	GO:0045979	55	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.012
regulation of response to wounding	GO:1903034	69	0.012
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.012
negative regulation of macromolecule metabolic process	GO:0010605	260	0.012
positive regulation of signaling	GO:0023056	270	0.012
formation of primary germ layer	GO:0001704	1	0.012
innate immune response	GO:0045087	35	0.012
cellular carbohydrate metabolic process	GO:0044262	72	0.012
positive regulation of secretion	GO:0051047	140	0.012
response to activity	GO:0014823	73	0.012
regulation of cell growth	GO:0001558	85	0.012	Rat
sexual reproduction	GO:0019953	148	0.012
secondary metabolite catabolic process	GO:0090487	1	0.012
mesoderm development	GO:0007498	2	0.012
regulation of organic acid transport	GO:0032890	35	0.012
negative regulation of cell projection organization	GO:0031345	50	0.011
hormone secretion	GO:0046879	115	0.011
sulfur compound transport	GO:0072348	8	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.011
negative regulation of transport	GO:0051051	136	0.011	Yeast
regulation of amino acid transport	GO:0051955	25	0.011
terpenoid metabolic process	GO:0006721	37	0.011
response to mercury ion	GO:0046689	15	0.011
glial cell differentiation	GO:0010001	65	0.011
proteolysis	GO:0006508	175	0.011
organ induction	GO:0001759	1	0.011
response to amino acid	GO:0043200	75	0.011
carbohydrate phosphorylation	GO:0046835	16	0.011
reproductive process	GO:0022414	372	0.011	Worm
hormone transport	GO:0009914	121	0.011
lipid biosynthetic process	GO:0008610	128	0.011	Yeast
chromosome segregation	GO:0007059	2	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
regulation of cell cycle	GO:0051726	73	0.011	Rat
positive regulation of cellular component organization	GO:0051130	200	0.011	Yeast Rat
cellular response to methylglyoxal	GO:0097238	1	0.011
regulation of establishment of protein localization	GO:0070201	69	0.011
reactive oxygen species biosynthetic process	GO:1903409	8	0.011
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.011
embryo development	GO:0009790	49	0.011	Worm
negative regulation of neuron projection development	GO:0010977	46	0.011
serine family amino acid biosynthetic process	GO:0009070	4	0.011
divalent inorganic cation transport	GO:0072511	134	0.011
glutathione transport	GO:0034635	2	0.011
negative regulation of signaling	GO:0023057	157	0.011
regulation of membrane potential	GO:0042391	110	0.011
negative regulation of growth	GO:0045926	37	0.011
oxidoreduction coenzyme metabolic process	GO:0006733	31	0.010
regulation of immune system process	GO:0002682	123	0.010
digestive system development	GO:0055123	41	0.010
regulation of nucleotide metabolic process	GO:0006140	117	0.010
nucleic acid templated transcription	GO:0097659	379	0.010	Yeast
organic hydroxy compound metabolic process	GO:1901615	115	0.010
regulation of generation of precursor metabolites and energy	GO:0043467	18	0.010
hexose transport	GO:0008645	29	0.010
signal transduction by phosphorylation	GO:0023014	144	0.010
regulation of growth	GO:0040008	105	0.010	Rat Worm
response to ethanol	GO:0045471	162	0.010
positive regulation of nucleotide catabolic process	GO:0030813	53	0.010
cellular component movement	GO:0006928	248	0.010

Sgk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
endocrine system disease	DOID:28	0.011
hypothyroidism	DOID:1459	0.011
disease of anatomical entity	DOID:7	0.011
thyroid gland disease	DOID:50	0.011
congenital hypothyroidism	DOID:0050328	0.011

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