Rattus norvegicus

67 known processes

Numb

numb homolog (Drosophila)

(Aliases: MGC188364)

Numb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component organizationGO:00511283680.111
regulation of rna biosynthetic processGO:20011413810.056
protein complex subunit organizationGO:00718223020.053
intracellular signal transductionGO:00355563140.052
regulation of molecular functionGO:00650093980.052
rna metabolic processGO:00160704060.050
cellular component assemblyGO:00226073600.048
regulation of neurogenesisGO:00507672470.047
nucleic acid templated transcriptionGO:00976593790.047
cell cell signalingGO:00072673350.046
secretionGO:00469033070.045
regulation of signal transductionGO:00099663180.044
regulation of transcription dna templatedGO:00063553740.044
cellular amino acid metabolic processGO:00065201070.043
regulation of rna metabolic processGO:00512523910.043
organelle organizationGO:00069962660.042
carboxylic acid metabolic processGO:00197522890.042
transcription dna templatedGO:00063513770.042
rna biosynthetic processGO:00327743800.040
regulation of nucleic acid templated transcriptionGO:19035063800.039
catabolic processGO:00090563510.039
cellular component biogenesisGO:00440853680.038
oxoacid metabolic processGO:00434362900.036
transmembrane transportGO:00550854120.036
nucleobase containing small molecule metabolic processGO:00550863160.035
vesicle mediated transportGO:00161921810.035
programmed cell deathGO:00125013920.035
negative regulation of macromolecule metabolic processGO:00106052600.034
negative regulation of cellular metabolic processGO:00313242810.034
ras protein signal transductionGO:0007265290.034
regulation of intracellular signal transductionGO:19025312180.033
negative regulation of biosynthetic processGO:00098901680.033
negative regulation of nitrogen compound metabolic processGO:00511721610.032
cellular response to oxygen containing compoundGO:19017013860.032
regulation of cell differentiationGO:00455953200.032
regulation of phosphate metabolic processGO:00192203490.032
organic substance catabolic processGO:19015753160.032
cellular response to stressGO:00335542690.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
cellular catabolic processGO:00442482950.031
monovalent inorganic cation transportGO:00156721720.031
regulation of multicellular organismal developmentGO:20000263760.030
cellular amine metabolic processGO:0044106380.030
positive regulation of response to stimulusGO:00485842850.030
regulation of cell developmentGO:00602842630.030
apoptotic processGO:00069153810.029
single organism catabolic processGO:00447122830.029
cation transportGO:00068123820.029
positive regulation of phosphate metabolic processGO:00459372620.029
ion transmembrane transportGO:00342203650.029
amine metabolic processGO:0009308380.029
protein complex assemblyGO:00064612630.029
carbohydrate derivative metabolic processGO:19011353460.029
negative regulation of cellular biosynthetic processGO:00313271610.028
macromolecular complex subunit organizationGO:00439333390.028
positive regulation of phosphorus metabolic processGO:00105622620.028
protein complex biogenesisGO:00702712630.028
organic acid metabolic processGO:00060822920.028
response to nutrient levelsGO:00316673700.028
neuron differentiationGO:00301823680.027
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
regulation of cellular ketone metabolic processGO:0010565270.027
protein autophosphorylationGO:0046777660.027
purine ribonucleotide metabolic processGO:00091502270.027
positive regulation of multicellular organismal processGO:00512403870.027
regulation of cellular amine metabolic processGO:003323880.026
central nervous system developmentGO:00074173110.026
cellular ketone metabolic processGO:0042180510.026
negative regulation of multicellular organismal processGO:00512412030.026
regulation of neuron differentiationGO:00456642080.026
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
macromolecular complex assemblyGO:00650032730.025
regulation of phosphorus metabolic processGO:00511743490.025
cell projection organizationGO:00300303020.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
regulation of system processGO:00440572080.025
positive regulation of molecular functionGO:00440932300.024
nitrogen compound transportGO:00717052290.024
defense responseGO:00069521940.024
regulation of response to stressGO:00801341260.024
regulation of proteasomal protein catabolic processGO:006113640.024
ribonucleoside metabolic processGO:00091191740.024
positive regulation of gene expressionGO:00106282440.023
regulation of nervous system developmentGO:00519602640.023
synaptic transmissionGO:00072682350.023
metal ion transportGO:00300012890.023
cell part morphogenesisGO:00329901230.023
positive regulation of biosynthetic processGO:00098913190.023
nucleotide metabolic processGO:00091172790.023
neuron developmentGO:00486662860.023
protein phosphorylationGO:00064683450.023
head developmentGO:00603222470.022
regulation of cellular amino acid metabolic processGO:000652120.022
regulation of protein modification processGO:00313991940.022
dna integrity checkpointGO:003157020.022
positive regulation of cellular biosynthetic processGO:00313282950.022
negative regulation of gene expressionGO:00106291990.022
response to extracellular stimulusGO:00099913800.022
regulation of phosphorylationGO:00423252480.021
organic cyclic compound catabolic processGO:19013611750.021
positive regulation of cellular component organizationGO:00511302000.021
nucleoside metabolic processGO:00091161790.021
regulation of apoptotic processGO:00429813350.021
anatomical structure morphogenesisGO:00096532980.020
signal releaseGO:00230611450.020
protein oligomerizationGO:00512591910.020
small gtpase mediated signal transductionGO:0007264360.020
regulation of catalytic activityGO:00507903040.020
positive regulation of transcription dna templatedGO:00458931970.020
positive regulation of transportGO:00510502450.020
purine nucleotide metabolic processGO:00061632290.020
organophosphate metabolic processGO:00196373700.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
organonitrogen compound catabolic processGO:19015651790.020
cation transmembrane transportGO:00986552630.020
secretion by cellGO:00329402480.020
macromolecule localizationGO:00330362520.020
cell morphogenesisGO:00009021420.020
response to cytokineGO:00340972150.020
positive regulation of cell differentiationGO:00455972170.020
glycosyl compound metabolic processGO:19016571820.020
ribonucleotide metabolic processGO:00092592310.020
regulation of programmed cell deathGO:00430673410.019
reproductive processGO:00224143720.019
protein localizationGO:00081041910.019
regulation of protein metabolic processGO:00512462890.019
positive regulation of phosphorylationGO:00423271770.019
neuron projection developmentGO:00311752730.019
dna metabolic processGO:0006259960.019
cell cycle checkpointGO:000007520.019
purine containing compound metabolic processGO:00725212530.019
negative regulation of metabolic processGO:00098923310.019
regulation of ion transmembrane transportGO:00347651210.019
cellular response to nitrogen compoundGO:19016992100.019
ribose phosphate metabolic processGO:00196932350.019
brain developmentGO:00074202470.018
positive regulation of developmental processGO:00510942830.018
regulation of cellular protein metabolic processGO:00322682670.018
transcription from rna polymerase ii promoterGO:00063662520.018
positive regulation of catalytic activityGO:00430851840.018
lipid metabolic processGO:00066292830.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
ribonucleoside triphosphate metabolic processGO:00091991410.018
positive regulation of neurogenesisGO:00507691650.018
multi organism reproductive processGO:00447032620.018
inorganic cation transmembrane transportGO:00986622020.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
regulation of membrane potentialGO:00423911100.017
heart morphogenesisGO:000300730.017
nucleobase containing compound catabolic processGO:00346551520.017
positive regulation of cellular amine metabolic processGO:003324030.017
cell morphogenesis involved in differentiationGO:00009041190.017
protein heterooligomerizationGO:0051291890.017
purine nucleoside metabolic processGO:00422781690.017
membrane organizationGO:0061024940.017
regulation of ion transportGO:00432692450.017
regulation of protein phosphorylationGO:00019321830.017
synaptic growth at neuromuscular junctionGO:005112410.017
heterocycle catabolic processGO:00467001670.017
immune responseGO:00069551040.017
positive regulation of cellular protein metabolic processGO:00322701670.016
aromatic compound catabolic processGO:00194391680.016
endocytosisGO:0006897840.016
cellular nitrogen compound catabolic processGO:00442701630.016
proteolysisGO:00065081750.016
response to oxidative stressGO:00069791860.016
reproductionGO:00000032450.016
positive regulation of programmed cell deathGO:00430681570.016
positive regulation of rna metabolic processGO:00512542030.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
response to growth factorGO:00708481890.015
purine nucleoside triphosphate metabolic processGO:00091441410.015
positive regulation of nervous system developmentGO:00519621780.015
positive regulation of signal transductionGO:00099671750.015
agingGO:00075682410.015
action potentialGO:0001508540.015
nucleoside phosphate metabolic processGO:00067532830.015
steroid metabolic processGO:0008202730.015
negative regulation of developmental processGO:00510931250.015
response to oxygen levelsGO:00704822650.015
homeostatic processGO:00425923310.015
nucleoside catabolic processGO:00091641260.015
regulation of metal ion transportGO:00109591180.015
regulation of catabolic processGO:00098941130.015
cell type specific apoptotic processGO:00972851340.015
chemical homeostasisGO:00488782920.015
regulation of cell projection organizationGO:00313441750.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
muscle system processGO:00030121150.014
positive regulation of intracellular signal transductionGO:19025331380.014
regulation of hormone levelsGO:00108171870.014
cell projection morphogenesisGO:00488581230.014
anion transportGO:00068201780.014
positive regulation of cell developmentGO:00107201760.014
regulation of cell proliferationGO:00421273590.014
response to peptide hormoneGO:00434342780.014
cellular response to endogenous stimulusGO:00714953770.014
regulation of neuron projection developmentGO:00109751610.014
positive regulation of cell communicationGO:00106472710.014
single organism reproductive processGO:00447022970.014
inorganic ion transmembrane transportGO:00986602290.014
response to peptideGO:19016522920.014
negative regulation of cellular component organizationGO:0051129830.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
axis specificationGO:000979840.014
purine ribonucleoside metabolic processGO:00461281680.014
single organism organelle organizationGO:19025891800.014
positive regulation of rna biosynthetic processGO:19026801970.014
cellular response to hormone stimulusGO:00328702470.014
negative regulation of response to stimulusGO:00485851550.014
positive regulation of signalingGO:00230562700.014
negative regulation of rna metabolic processGO:00512531230.014
cellular macromolecule localizationGO:00707271220.014
intracellular transportGO:00469071850.014
eye morphogenesisGO:004859240.014
immune system processGO:00023762040.014
positive regulation of protein metabolic processGO:00512471780.013
organelle localizationGO:0051640550.013
regulation of transmembrane transportGO:00347621220.013
circulatory system processGO:00030131830.013
positive regulation of purine nucleotide metabolic processGO:1900544910.013
response to glucoseGO:00097491360.013
cellular response to external stimulusGO:00714961180.013
response to ethanolGO:00454711620.013
multicellular organism reproductionGO:00325042330.013
oxidation reduction processGO:00551143040.013
embryonic pattern specificationGO:000988010.013
multicellular organismal reproductive processGO:00486092330.013
neuron deathGO:00709971270.013
negative regulation of cell deathGO:00605482290.013
response to insulinGO:00328681330.013
cellular response to organonitrogen compoundGO:00714171970.013
anterior posterior pattern specificationGO:000995210.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
purine ribonucleoside catabolic processGO:00461301240.013
response to hypoxiaGO:00016662310.012
negative regulation of cell communicationGO:00106481580.012
glycosyl compound catabolic processGO:19016581260.012
negative regulation of rna biosynthetic processGO:19026791180.012
positive regulation of apoptotic processGO:00430651540.012
regulation of secretion by cellGO:19035302080.012
response to inorganic substanceGO:00100353770.012
blood circulationGO:00080151830.012
establishment of organelle localizationGO:0051656370.012
cellular response to cytokine stimulusGO:00713451270.012
multicellular organismal signalingGO:0035637440.012
neurological system processGO:00508772190.012
ribonucleotide catabolic processGO:00092611360.012
guanosine containing compound metabolic processGO:1901068740.012
cellular homeostasisGO:00197252520.012
response to nutrientGO:00075842480.012
circadian rhythmGO:0007623880.012
regulation of ion transmembrane transporter activityGO:0032412480.012
response to external biotic stimulusGO:00432072210.012
signal transduction by phosphorylationGO:00230141440.012
negative regulation of cell differentiationGO:0045596990.012
regulation of cell cycleGO:0051726730.012
regulation of secretionGO:00510462240.012
single organism intracellular transportGO:19025821660.012
organonitrogen compound biosynthetic processGO:19015661670.011
adult locomotory behaviorGO:000834440.011
cellular lipid metabolic processGO:00442552080.011
nucleoside triphosphate catabolic processGO:00091431230.011
response to corticosteroidGO:00319602350.011
cellular component morphogenesisGO:00329891550.011
regenerationGO:00310991630.011
response to biotic stimulusGO:00096072260.011
growthGO:00400071650.011
positive regulation of protein modification processGO:00314011420.011
regulation of hydrolase activityGO:00513361430.011
rhythmic processGO:00485111560.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
multicellular organism growthGO:003526410.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
response to ketoneGO:19016541820.011
response to decreased oxygen levelsGO:00362932370.011
rho protein signal transductionGO:0007266110.011
cellular response to peptideGO:19016531330.011
alcohol metabolic processGO:0006066770.011
regulation of neuron deathGO:19012141150.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
positive regulation of cell proliferationGO:00082842490.011
cellular component movementGO:00069282480.011
sex differentiationGO:00075481130.011
negative regulation of cell developmentGO:0010721820.011
regulation of muscle system processGO:0090257790.011
regulation of organelle organizationGO:0033043800.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
rna localizationGO:000640340.011
positive regulation of catabolic processGO:0009896780.011
response to glucocorticoidGO:00513842230.011
cellular chemical homeostasisGO:00550822470.011
chromosome segregationGO:000705920.011
response to acid chemicalGO:00011012220.011
organophosphate catabolic processGO:00464341480.011
ribonucleoside catabolic processGO:00424541260.011
regulation of gtpase activityGO:0043087570.010
cytoplasmic transportGO:00164821150.010
organic hydroxy compound metabolic processGO:19016151150.010
negative regulation of transportGO:00510511360.010
cellular response to extracellular stimulusGO:0031668730.010
cellular protein localizationGO:00346131220.010
amide transportGO:00428861050.010
neuron projection morphogenesisGO:00488121220.010
carbohydrate derivative catabolic processGO:19011361470.010
reproductive structure developmentGO:00486081280.010
positive regulation of nucleotide metabolic processGO:0045981910.010
negative regulation of molecular functionGO:00440921330.010
nucleoside phosphate catabolic processGO:19012921400.010
regulation of protein kinase activityGO:00458591050.010
mapk cascadeGO:00001651400.010
cardiac chamber developmentGO:000320510.010
positive regulation of gtp catabolic processGO:0033126480.010
regulation of purine nucleotide catabolic processGO:0033121650.010

Numb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.012
inherited metabolic disorderDOID:65500.012
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012