IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Cyp39a1

cytochrome P450, family 39, subfamily a, polypeptide 1

Entrez: 301264
RGD: 1307471
Ensembl: ENSRNOG00000010519
UniProtKB: D4AE09

Process Predictions
Disease Predictions

Cyp39a1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
organic acid metabolic process	GO:0006082	292	0.131	Human Mouse Rat
carboxylic acid metabolic process	GO:0019752	289	0.125	Human Mouse Rat
cellular response to endogenous stimulus	GO:0071495	377	0.082
oxoacid metabolic process	GO:0043436	290	0.081	Human Mouse Rat
response to nutrient levels	GO:0031667	370	0.076
response to extracellular stimulus	GO:0009991	380	0.073
multi organism reproductive process	GO:0044703	262	0.064
lipid metabolic process	GO:0006629	283	0.057	Human Mouse Rat
chemical homeostasis	GO:0048878	292	0.051
monocarboxylic acid metabolic process	GO:0032787	152	0.047	Human Mouse Rat
response to acid chemical	GO:0001101	222	0.046
cellular ketone metabolic process	GO:0042180	51	0.045
neurological system process	GO:0050877	219	0.043	Rat
response to biotic stimulus	GO:0009607	226	0.041
cellular amine metabolic process	GO:0044106	38	0.039
single organism biosynthetic process	GO:0044711	342	0.039	Human Mouse Rat
response to purine containing compound	GO:0014074	126	0.039	Rat
response to nutrient	GO:0007584	248	0.038
response to camp	GO:0051591	91	0.038	Rat
amine metabolic process	GO:0009308	38	0.038
cellular lipid metabolic process	GO:0044255	208	0.038	Rat
cellular response to organic cyclic compound	GO:0071407	202	0.036
single organism catabolic process	GO:0044712	283	0.034	Mouse
multicellular organism reproduction	GO:0032504	233	0.034
cellular component assembly	GO:0022607	360	0.034
regulation of cellular ketone metabolic process	GO:0010565	27	0.034
homeostatic process	GO:0042592	331	0.034
transmembrane transport	GO:0055085	412	0.033
cation transport	GO:0006812	382	0.033
intracellular signal transduction	GO:0035556	314	0.032
cellular amino acid metabolic process	GO:0006520	107	0.032
behavior	GO:0007610	205	0.031	Rat
organic substance catabolic process	GO:1901575	316	0.031	Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.031
circulatory system process	GO:0003013	183	0.031
cellular response to hormone stimulus	GO:0032870	247	0.030
nitrogen compound transport	GO:0071705	229	0.030
response to organophosphorus	GO:0046683	102	0.030	Rat
regulation of molecular function	GO:0065009	398	0.030
cellular response to oxygen containing compound	GO:1901701	386	0.028
reproduction	GO:0000003	245	0.028
blood circulation	GO:0008015	183	0.028
multicellular organismal reproductive process	GO:0048609	233	0.028
rna metabolic process	GO:0016070	406	0.028
carboxylic acid transport	GO:0046942	115	0.027
regulation of cellular component organization	GO:0051128	368	0.027
ion transmembrane transport	GO:0034220	365	0.027
reproductive process	GO:0022414	372	0.027
response to decreased oxygen levels	GO:0036293	237	0.027	Rat
oxidation reduction process	GO:0055114	304	0.026	Human Mouse Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.026
alcohol metabolic process	GO:0006066	77	0.026	Mouse
response to hypoxia	GO:0001666	231	0.026	Rat
regulation of rna biosynthetic process	GO:2001141	381	0.026
regulation of catalytic activity	GO:0050790	304	0.026
cellular response to stress	GO:0033554	269	0.025
anion transport	GO:0006820	178	0.025
response to oxygen levels	GO:0070482	265	0.025	Rat
response to ketone	GO:1901654	182	0.025
reactive oxygen species metabolic process	GO:0072593	37	0.024
regulation of system process	GO:0044057	208	0.024
regulation of cell proliferation	GO:0042127	359	0.024
response to inorganic substance	GO:0010035	377	0.023
response to vitamin	GO:0033273	131	0.023
organic anion transport	GO:0015711	132	0.023
synaptic transmission	GO:0007268	235	0.023
negative regulation of molecular function	GO:0044092	133	0.023
organophosphate metabolic process	GO:0019637	370	0.023
organic hydroxy compound metabolic process	GO:1901615	115	0.023	Human Mouse
macromolecular complex subunit organization	GO:0043933	339	0.023
response to peptide hormone	GO:0043434	278	0.022
cellular response to insulin stimulus	GO:0032869	81	0.022
cellular chemical homeostasis	GO:0055082	247	0.022
macromolecule localization	GO:0033036	252	0.022
negative regulation of macromolecule metabolic process	GO:0010605	260	0.022
rna biosynthetic process	GO:0032774	380	0.022
cellular response to organonitrogen compound	GO:0071417	197	0.022
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.022
regulation of cellular amine metabolic process	GO:0033238	8	0.022
aging	GO:0007568	241	0.022
transmission of nerve impulse	GO:0019226	42	0.022
cardiovascular system development	GO:0072358	134	0.021
macromolecular complex assembly	GO:0065003	273	0.021
negative regulation of metabolic process	GO:0009892	331	0.021
cellular component biogenesis	GO:0044085	368	0.021
cation transmembrane transport	GO:0098655	263	0.021
cation homeostasis	GO:0055080	195	0.021
negative regulation of innate immune response	GO:0045824	4	0.021
positive regulation of cellular amine metabolic process	GO:0033240	3	0.021
ion homeostasis	GO:0050801	212	0.020
secretion	GO:0046903	307	0.020
single organism intracellular transport	GO:1902582	166	0.020
response to corticosteroid	GO:0031960	235	0.020
cellular homeostasis	GO:0019725	252	0.020
transcription dna templated	GO:0006351	377	0.020
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.020
regulation of nucleic acid templated transcription	GO:1903506	380	0.020
vesicle mediated transport	GO:0016192	181	0.020
programmed cell death	GO:0012501	392	0.020
intracellular transport	GO:0046907	185	0.020
protein localization	GO:0008104	191	0.020
organic acid biosynthetic process	GO:0016053	83	0.019	Human Mouse Rat
cellular catabolic process	GO:0044248	295	0.019
growth	GO:0040007	165	0.019
protein complex subunit organization	GO:0071822	302	0.019
head development	GO:0060322	247	0.019
lipid biosynthetic process	GO:0008610	128	0.019	Human Mouse Rat
negative regulation of gene expression	GO:0010629	199	0.019
multi multicellular organism process	GO:0044706	138	0.018
response to insulin	GO:0032868	133	0.018
regulation of nervous system development	GO:0051960	264	0.018
protein complex biogenesis	GO:0070271	263	0.018
regulation of cell motility	GO:2000145	131	0.018
immune response	GO:0006955	104	0.018
response to external biotic stimulus	GO:0043207	221	0.017
small molecule biosynthetic process	GO:0044283	124	0.017	Human Mouse Rat
reactive nitrogen species metabolic process	GO:2001057	1	0.017
circulatory system development	GO:0072359	134	0.017
regulation of rna metabolic process	GO:0051252	391	0.017
female pregnancy	GO:0007565	122	0.017
catabolic process	GO:0009056	351	0.017	Mouse
regulation of hydrolase activity	GO:0051336	143	0.017
protein complex assembly	GO:0006461	263	0.017
cellular response to lipid	GO:0071396	201	0.017
cellular macromolecule localization	GO:0070727	122	0.017
regulation of phosphorylation	GO:0042325	248	0.017
response to transition metal nanoparticle	GO:1990267	122	0.017
regulation of programmed cell death	GO:0043067	341	0.016
proteolysis	GO:0006508	175	0.016
single organism reproductive process	GO:0044702	297	0.016
response to estrogen	GO:0043627	232	0.016
regulation of multicellular organismal development	GO:2000026	376	0.016
defense response	GO:0006952	194	0.016
single organism cellular localization	GO:1902580	102	0.016
positive regulation of cell death	GO:0010942	184	0.016
negative regulation of cellular metabolic process	GO:0031324	281	0.016
organic acid transport	GO:0015849	116	0.016
regulation of intracellular signal transduction	GO:1902531	218	0.015
regulation of anatomical structure size	GO:0090066	135	0.015
positive regulation of biosynthetic process	GO:0009891	319	0.015
regulation of transcription dna templated	GO:0006355	374	0.015
regulation of protein metabolic process	GO:0051246	289	0.015
neuron projection development	GO:0031175	273	0.015
response to carbohydrate	GO:0009743	183	0.015
metal ion transport	GO:0030001	289	0.015
cellular response to peptide	GO:1901653	133	0.015
carbohydrate metabolic process	GO:0005975	130	0.015
cellular response to nitrogen compound	GO:1901699	210	0.015
regulation of phosphate metabolic process	GO:0019220	349	0.015
regulation of cell differentiation	GO:0045595	320	0.015
protein processing	GO:0016485	68	0.015
protein phosphorylation	GO:0006468	345	0.015
regulation of neurogenesis	GO:0050767	247	0.015
establishment of protein localization	GO:0045184	141	0.014
nucleobase containing small molecule metabolic process	GO:0055086	316	0.014
organic cyclic compound catabolic process	GO:1901361	175	0.014	Mouse
carbohydrate derivative metabolic process	GO:1901135	346	0.014
nucleic acid templated transcription	GO:0097659	379	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.014
single organism organelle organization	GO:1902589	180	0.014
muscle system process	GO:0003012	115	0.014
small molecule catabolic process	GO:0044282	59	0.014	Mouse
response to reactive oxygen species	GO:0000302	120	0.014
multicellular organismal signaling	GO:0035637	44	0.014
regulation of hormone levels	GO:0010817	187	0.014
positive regulation of cell proliferation	GO:0008284	249	0.014
regulation of neuron projection development	GO:0010975	161	0.014
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.014
regulation of cellular protein metabolic process	GO:0032268	267	0.014
rhythmic process	GO:0048511	156	0.013	Rat
anion transmembrane transport	GO:0098656	77	0.013
response to hexose	GO:0009746	144	0.013
cellular protein localization	GO:0034613	122	0.013
lipid storage	GO:0019915	1	0.013
negative regulation of cell proliferation	GO:0008285	119	0.013
response to metal ion	GO:0010038	253	0.013
immune system process	GO:0002376	204	0.013
response to peptide	GO:1901652	292	0.013
negative regulation of catalytic activity	GO:0043086	103	0.013
cellular response to alcohol	GO:0097306	87	0.013
reactive oxygen species biosynthetic process	GO:1903409	8	0.013
organic hydroxy compound transport	GO:0015850	77	0.013
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.013
localization of cell	GO:0051674	202	0.013
sexual reproduction	GO:0019953	148	0.013
positive regulation of molecular function	GO:0044093	230	0.013
positive regulation of gene expression	GO:0010628	244	0.013
cellular response to acid chemical	GO:0071229	75	0.013
regulation of lipid metabolic process	GO:0019216	68	0.013
negative regulation of cell death	GO:0060548	229	0.013
cellular response to external stimulus	GO:0071496	118	0.013
fatty acid metabolic process	GO:0006631	99	0.013	Rat
positive regulation of cell development	GO:0010720	176	0.013
regulation of phosphorus metabolic process	GO:0051174	349	0.013
apoptotic process	GO:0006915	381	0.013
cell cell signaling	GO:0007267	335	0.013
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.013
protein oligomerization	GO:0051259	191	0.013
protein maturation	GO:0051604	68	0.012
positive regulation of developmental process	GO:0051094	283	0.012
organonitrogen compound catabolic process	GO:1901565	179	0.012
axis specification	GO:0009798	4	0.012
positive regulation of programmed cell death	GO:0043068	157	0.012
purine ribonucleoside metabolic process	GO:0046128	168	0.012
small gtpase mediated signal transduction	GO:0007264	36	0.012
innate immune response	GO:0045087	35	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.012
negative regulation of response to tumor cell	GO:0002835	2	0.012
neuronal action potential	GO:0019228	35	0.012
locomotion	GO:0040011	237	0.012
regulation of signal transduction	GO:0009966	318	0.012
heart morphogenesis	GO:0003007	3	0.012
protein transport	GO:0015031	132	0.012
anatomical structure morphogenesis	GO:0009653	298	0.012
negative regulation of immune response to tumor cell	GO:0002838	2	0.012
aromatic compound catabolic process	GO:0019439	168	0.012
cellular nitrogen compound catabolic process	GO:0044270	163	0.012
response to activity	GO:0014823	73	0.012
cell growth	GO:0016049	104	0.012
cell migration	GO:0016477	197	0.012
glycerolipid metabolic process	GO:0046486	67	0.012
nucleoside metabolic process	GO:0009116	179	0.012
defense response to gram negative bacterium	GO:0050829	3	0.012
organelle organization	GO:0006996	266	0.012
cellular ion homeostasis	GO:0006873	184	0.012
glycosyl compound metabolic process	GO:1901657	182	0.012
negative regulation of protein metabolic process	GO:0051248	114	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.011
endocytosis	GO:0006897	84	0.011
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.011
sterol homeostasis	GO:0055092	3	0.011
positive regulation of catalytic activity	GO:0043085	184	0.011
response to fatty acid	GO:0070542	65	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
response to other organism	GO:0051707	220	0.011
male gamete generation	GO:0048232	99	0.011
kidney development	GO:0001822	67	0.011
lipid localization	GO:0010876	62	0.011
positive regulation of multicellular organismal process	GO:0051240	387	0.011
positive regulation of signaling	GO:0023056	270	0.011
chromosome segregation	GO:0007059	2	0.011
positive regulation of lipid catabolic process	GO:0050996	4	0.011
protein import	GO:0017038	37	0.011
response to oxidative stress	GO:0006979	186	0.011
renal system development	GO:0072001	67	0.011
purine containing compound metabolic process	GO:0072521	253	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
blood vessel development	GO:0001568	69	0.011
spermatogenesis	GO:0007283	99	0.011
regulation of apoptotic process	GO:0042981	335	0.011
heterocycle catabolic process	GO:0046700	167	0.011
nucleocytoplasmic transport	GO:0006913	48	0.011
central nervous system development	GO:0007417	311	0.011
response to molecule of bacterial origin	GO:0002237	194	0.011
regulation of membrane potential	GO:0042391	110	0.011
nucleoside phosphate metabolic process	GO:0006753	283	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.011
response to vitamin d	GO:0033280	34	0.011
positive regulation of phosphate metabolic process	GO:0045937	262	0.011
response to bacterium	GO:0009617	200	0.011
cellular cation homeostasis	GO:0030003	180	0.011
cellular response to peptide hormone stimulus	GO:0071375	120	0.011
positive regulation of neurogenesis	GO:0050769	165	0.011
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011
negative regulation of cellular biosynthetic process	GO:0031327	161	0.011
regulation of cell development	GO:0060284	263	0.011
protein import into nucleus	GO:0006606	35	0.011
nucleotide metabolic process	GO:0009117	279	0.011
regulation of growth	GO:0040008	105	0.011
blood vessel morphogenesis	GO:0048514	58	0.010
multicellular organism growth	GO:0035264	1	0.010
retinal metabolic process	GO:0042574	3	0.010
organonitrogen compound biosynthetic process	GO:1901566	167	0.010
response to glucocorticoid	GO:0051384	223	0.010
regulation of ion transport	GO:0043269	245	0.010
positive regulation of response to stimulus	GO:0048584	285	0.010
protein homooligomerization	GO:0051260	91	0.010
cell projection organization	GO:0030030	302	0.010
intracellular protein transport	GO:0006886	79	0.010
positive regulation of phosphorus metabolic process	GO:0010562	262	0.010
gamete generation	GO:0007276	124	0.010
regulation of secretion	GO:0051046	224	0.010
action potential	GO:0001508	54	0.010
brain development	GO:0007420	247	0.010
organic hydroxy compound biosynthetic process	GO:1901617	51	0.010	Human Mouse
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.010
purine nucleoside metabolic process	GO:0042278	169	0.010
response to molecule of fungal origin	GO:0002238	3	0.010
amino acid transport	GO:0006865	70	0.010

Cyp39a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.031
inherited metabolic disorder	DOID:655	0.013
nervous system disease	DOID:863	0.010
disease of anatomical entity	DOID:7	0.010
musculoskeletal system disease	DOID:17	0.010

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