Rattus norvegicus

65 known processes

Tnfsf11

tumor necrosis factor (ligand) superfamily, member 11

(Aliases: RANKL)

Tnfsf11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of response to stimulusGO:00485842850.181
Human Rat
response to nutrient levelsGO:00316673700.171
Rat
regulation of programmed cell deathGO:00430673410.157
Rat
cellular response to endogenous stimulusGO:00714953770.149
regulation of apoptotic processGO:00429813350.133
Rat
cellular response to stressGO:00335542690.130
positive regulation of multicellular organismal processGO:00512403870.128
programmed cell deathGO:00125013920.122
Rat
cellular response to organic cyclic compoundGO:00714072020.115
response to extracellular stimulusGO:00099913800.107
Rat
response to ketoneGO:19016541820.106
response to cytokineGO:00340972150.101
Human
intracellular signal transductionGO:00355563140.095
Human Rat
apoptotic processGO:00069153810.093
Rat
multicellular organismal reproductive processGO:00486092330.091
response to lipopolysaccharideGO:00324961910.089
Rat
reproductive processGO:00224143720.085
Rat
positive regulation of signalingGO:00230562700.079
Human Rat
positive regulation of apoptotic processGO:00430651540.079
Rat
regulation of catalytic activityGO:00507903040.074
Human Rat
single organism reproductive processGO:00447022970.072
Rat
cellular ketone metabolic processGO:0042180510.071
cellular response to hormone stimulusGO:00328702470.070
neuron deathGO:00709971270.069
Rat
neuron developmentGO:00486662860.068
defense responseGO:00069521940.068
Rat
positive regulation of cell differentiationGO:00455972170.068
positive regulation of cell developmentGO:00107201760.065
Rat
macromolecular complex subunit organizationGO:00439333390.065
positive regulation of macromolecule biosynthetic processGO:00105572470.061
Human Rat
response to radiationGO:00093141370.061
positive regulation of biosynthetic processGO:00098913190.061
Human Rat
positive regulation of cell deathGO:00109421840.056
Rat
regulation of cell differentiationGO:00455953200.056
positive regulation of immune system processGO:0002684900.055
cellular response to lipidGO:00713962010.054
multicellular organism reproductionGO:00325042330.053
cell projection organizationGO:00300303020.053
regulation of cellular ketone metabolic processGO:0010565270.053
positive regulation of protein phosphorylationGO:00019341350.052
Human
regulation of intracellular signal transductionGO:19025312180.052
Human Rat
tube developmentGO:0035295890.051
regulation of multicellular organismal developmentGO:20000263760.049
g protein coupled receptor signaling pathwayGO:00071862420.049
cell type specific apoptotic processGO:00972851340.049
Rat
response to estrogenGO:00436272320.047
response to external biotic stimulusGO:00432072210.047
Rat
regulation of phosphate metabolic processGO:00192203490.047
Human
response to other organismGO:00517072200.046
Rat
cellular response to external stimulusGO:00714961180.046
nucleobase containing small molecule metabolic processGO:00550863160.046
regulation of neurogenesisGO:00507672470.045
Rat
regulation of neuron deathGO:19012141150.045
Rat
jak stat cascadeGO:0007259260.045
cellular catabolic processGO:00442482950.044
positive regulation of cell communicationGO:00106472710.044
Human Rat
inflammatory responseGO:00069541500.043
Rat
regulation of protein modification processGO:00313991940.043
Human
brain developmentGO:00074202470.042
single organism biosynthetic processGO:00447113420.042
response to estradiolGO:00323551640.041
cellular response to organonitrogen compoundGO:00714171970.041
carboxylic acid metabolic processGO:00197522890.041
positive regulation of rna biosynthetic processGO:19026801970.040
Human
protein phosphorylationGO:00064683450.040
Human
positive regulation of developmental processGO:00510942830.040
cell activationGO:0001775970.039
Human Rat
renal system developmentGO:0072001670.039
positive regulation of transcription dna templatedGO:00458931970.039
Human
cellular response to cytokine stimulusGO:00713451270.039
Human
immune system processGO:00023762040.038
cellular response to oxygen containing compoundGO:19017013860.038
macromolecular complex assemblyGO:00650032730.038
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.038
multi organism reproductive processGO:00447032620.038
single organism cell adhesionGO:0098602460.037
Human
regulation of nucleotide metabolic processGO:00061401170.037
sexual reproductionGO:00199531480.037
regulation of phosphorylationGO:00423252480.037
Human
protein complex subunit organizationGO:00718223020.035
positive regulation of rna metabolic processGO:00512542030.035
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.034
Human
neuron projection developmentGO:00311752730.034
positive regulation of molecular functionGO:00440932300.034
Human Rat
regenerationGO:00310991630.034
response to growth factorGO:00708481890.033
Rat
positive regulation of neurogenesisGO:00507691650.033
Rat
development of primary sexual characteristicsGO:00451371070.033
Rat
rhythmic processGO:00485111560.033
response to nutrientGO:00075842480.033
Rat
positive regulation of cell proliferationGO:00082842490.033
Rat
neuron differentiationGO:00301823680.032
response to ethanolGO:00454711620.032
cellular response to extracellular stimulusGO:0031668730.032
organonitrogen compound catabolic processGO:19015651790.031
cellular component biogenesisGO:00440853680.031
positive regulation of protein metabolic processGO:00512471780.031
Human Rat
positive regulation of phosphate metabolic processGO:00459372620.031
Human
response to peptideGO:19016522920.031
Rat
calcium ion transportGO:00068161310.031
positive regulation of phosphorus metabolic processGO:00105622620.031
Human
macromolecule localizationGO:00330362520.030
Rat
positive regulation of jak stat cascadeGO:0046427190.030
positive regulation of nervous system developmentGO:00519621780.030
Rat
regulation of cellular amine metabolic processGO:003323880.030
nucleoside phosphate metabolic processGO:00067532830.029
divalent inorganic cation transportGO:00725111340.029
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.029
Rat
gamete generationGO:00072761240.029
activation of janus kinase activityGO:004297650.029
regulation of phosphorus metabolic processGO:00511743490.029
Human
homeostatic processGO:00425923310.028
regulation of cellular protein metabolic processGO:00322682670.028
Human Rat
protein localizationGO:00081041910.028
Rat
positive regulation of phosphorylationGO:00423271770.028
Human
positive regulation of catalytic activityGO:00430851840.028
Human Rat
positive regulation of programmed cell deathGO:00430681570.028
Rat
steroid metabolic processGO:0008202730.028
response to ionizing radiationGO:0010212590.027
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
Human
regulation of protein metabolic processGO:00512462890.027
Human Rat
response to oxygen levelsGO:00704822650.027
Rat
protein complex assemblyGO:00064612630.026
response to woundingGO:00096112540.026
Rat
vitamin d metabolic processGO:004235940.026
cell adhesionGO:00071551100.025
Human
protein complex biogenesisGO:00702712630.025
neuron apoptotic processGO:0051402880.025
Rat
reproductionGO:00000032450.025
cellular homeostasisGO:00197252520.025
Rat
positive regulation of gene expressionGO:00106282440.025
Human
neuropeptide signaling pathwayGO:0007218290.024
regulation of hormone levelsGO:00108171870.024
response to corticosteroidGO:00319602350.024
wound healingGO:00420601220.024
positive regulation of intracellular signal transductionGO:19025331380.024
Human Rat
regulation of jak stat cascadeGO:0046425210.024
catabolic processGO:00090563510.024
carbohydrate derivative catabolic processGO:19011361470.024
purine containing compound metabolic processGO:00725212530.024
camp metabolic processGO:0046058630.023
cellular response to ammonium ionGO:0071242170.023
gonad developmentGO:00084061040.023
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.023
central nervous system developmentGO:00074173110.023
proteolysisGO:00065081750.023
Rat
gastrulationGO:000736920.022
ribose phosphate metabolic processGO:00196932350.022
organic cyclic compound catabolic processGO:19013611750.022
positive regulation of hydrolase activityGO:0051345860.022
Rat
response to alkaloidGO:00432791320.022
glycosyl compound metabolic processGO:19016571820.022
organic substance catabolic processGO:19015753160.022
positive regulation of neuron differentiationGO:00456661260.022
amine metabolic processGO:0009308380.022
cellular cation homeostasisGO:00300031800.022
Rat
metal ion transportGO:00300012890.022
response to glucocorticoidGO:00513842230.022
spermatogenesisGO:0007283990.022
cellular component movementGO:00069282480.022
Human
negative regulation of metabolic processGO:00098923310.021
immune system developmentGO:0002520410.021
positive regulation of cellular component organizationGO:00511302000.021
Rat
chemical homeostasisGO:00488782920.021
Rat
regulation of transferase activityGO:00513381230.021
Human
positive regulation of neuron projection developmentGO:0010976990.021
regulation of cell proliferationGO:00421273590.021
Rat
liver developmentGO:0001889900.021
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.021
cellular amine metabolic processGO:0044106380.021
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.020
aromatic compound catabolic processGO:00194391680.020
purine nucleotide metabolic processGO:00061632290.020
localization of cellGO:00516742020.020
Human
regulation of anatomical structure sizeGO:00900661350.020
appendage morphogenesisGO:003510740.020
secretion by cellGO:00329402480.020
Rat
organophosphate catabolic processGO:00464341480.020
response to molecule of bacterial originGO:00022371940.020
Rat
regulation of leukocyte proliferationGO:0070663260.020
Rat
antigen receptor mediated signaling pathwayGO:005085110.020
cytosolic calcium ion homeostasisGO:00514801400.020
positive regulation of cellular protein metabolic processGO:00322701670.020
Human Rat
regulation of rna biosynthetic processGO:20011413810.020
Human
anatomical structure morphogenesisGO:00096532980.020
divalent inorganic cation homeostasisGO:00725071650.020
agingGO:00075682410.019
response to monosaccharideGO:00342841590.019
gland developmentGO:00487321550.019
response to peptide hormoneGO:00434342780.019
Rat
regulation of protein phosphorylationGO:00019321830.019
Human
single organism catabolic processGO:00447122830.019
immune responseGO:00069551040.019
Rat
cation transportGO:00068123820.019
carbohydrate derivative metabolic processGO:19011353460.019
regulation of cellular component organizationGO:00511283680.019
Rat
ovulation cycleGO:0042698670.019
hepaticobiliary system developmentGO:0061008900.018
nucleotide metabolic processGO:00091172790.018
cellular component assemblyGO:00226073600.018
cation homeostasisGO:00550801950.018
Rat
cellular nitrogen compound catabolic processGO:00442701630.018
forebrain developmentGO:0030900980.018
divalent metal ion transportGO:00708381320.018
purine ribonucleotide biosynthetic processGO:0009152810.018
positive regulation of protein modification processGO:00314011420.018
Human
regulation of response to stressGO:00801341260.018
Rat
secretionGO:00469033070.017
Rat
regulation of neuron differentiationGO:00456642080.017
regulation of signal transductionGO:00099663180.017
Human Rat
head developmentGO:00603222470.017
negative regulation of developmental processGO:00510931250.017
response to toxic substanceGO:00096361330.017
positive regulation of cell projection organizationGO:00313461110.017
regulation of cell developmentGO:00602842630.017
Rat
regulation of kinase activityGO:00435491170.017
Human
response to dexamethasoneGO:0071548490.017
multicellular organismal homeostasisGO:0048871490.017
positive regulation of signal transductionGO:00099671750.017
Human Rat
ribonucleotide metabolic processGO:00092592310.017
regulation of hormone secretionGO:00468831060.017
regulation of cellular amino acid metabolic processGO:000652120.017
nucleoside catabolic processGO:00091641260.016
regulation of secretion by cellGO:19035302080.016
Rat
mononuclear cell proliferationGO:0032943290.016
Rat
ribonucleotide biosynthetic processGO:0009260850.016
limb morphogenesisGO:003510840.016
negative regulation of biosynthetic processGO:00098901680.016
ras protein signal transductionGO:0007265290.016
regulation of body fluid levelsGO:0050878900.016
positive regulation of calcium ion transportGO:0051928360.016
negative regulation of cellular biosynthetic processGO:00313271610.016
urogenital system developmentGO:0001655780.016
calcium ion homeostasisGO:00550741620.016
embryonic appendage morphogenesisGO:003511340.016
peptidyl amino acid modificationGO:00181931260.015
organonitrogen compound biosynthetic processGO:19015661670.015
temperature homeostasisGO:0001659170.015
regulation of system processGO:00440572080.015
cell growthGO:00160491040.015
heterocycle catabolic processGO:00467001670.015
regulation of neuron projection developmentGO:00109751610.015
positive regulation of protein kinase activityGO:0045860730.015
Human
protein homooligomerizationGO:0051260910.015
female pregnancyGO:00075651220.015
regulation of cellular extravasationGO:000269120.015
nucleotide biosynthetic processGO:0009165980.015
negative regulation of nervous system developmentGO:0051961790.015
response to hexoseGO:00097461440.014
nucleobase containing compound catabolic processGO:00346551520.014
leukocyte activationGO:0045321760.014
Human Rat
dendrite morphogenesisGO:0048813430.014
neural crest cell developmentGO:001403220.014
regulation of ion transportGO:00432692450.014
Rat
small gtpase mediated signal transductionGO:0007264360.014
activation of protein kinase activityGO:0032147470.014
cellular response to nitrogen compoundGO:19016992100.014
gtp catabolic processGO:0006184710.014
regulation of lipid biosynthetic processGO:0046890380.014
cellular divalent inorganic cation homeostasisGO:00725031620.014
regulation of camp biosynthetic processGO:0030817380.014
cellular amino acid metabolic processGO:00065201070.014
regulation of nervous system developmentGO:00519602640.014
Rat
male gamete generationGO:0048232990.014
glutamate receptor signaling pathwayGO:0007215430.014
response to hypoxiaGO:00016662310.014
Rat
cellular macromolecule catabolic processGO:0044265290.014
regulation of protein kinase activityGO:00458591050.014
Human
cellular response to nutrient levelsGO:0031669600.014
organic hydroxy compound metabolic processGO:19016151150.014
establishment of protein localizationGO:00451841410.014
Rat
protein oligomerizationGO:00512591910.014
oxoacid metabolic processGO:00434362900.014
purine ribonucleotide metabolic processGO:00091502270.014
nucleoside triphosphate catabolic processGO:00091431230.014
developmental process involved in reproductionGO:00030061590.014
Rat
cerebral cortex tangential migrationGO:002180010.014
ribose phosphate biosynthetic processGO:0046390870.014
cytokine productionGO:0001816610.014
Rat
negative regulation of cellular component organizationGO:0051129830.013
regulation of cell projection organizationGO:00313441750.013
camp biosynthetic processGO:0006171470.013
behaviorGO:00076102050.013
response to ammonium ionGO:0060359710.013
innate immune responseGO:0045087350.013
axis specificationGO:000979840.013
cellular chemical homeostasisGO:00550822470.013
Rat
cellular response to alcoholGO:0097306870.013
embryonic limb morphogenesisGO:003032640.013
cellular response to growth factor stimulusGO:00713631620.013
cell part morphogenesisGO:00329901230.013
cellular response to oxygen levelsGO:0071453600.013
regulation of lipid metabolic processGO:0019216680.013
positive regulation of mononuclear cell proliferationGO:0032946200.013
Rat
sex differentiationGO:00075481130.013
Rat
purine nucleoside metabolic processGO:00422781690.013
synaptic transmissionGO:00072682350.013
Rat
organophosphate metabolic processGO:00196373700.012
transcription dna templatedGO:00063513770.012
Human
dendrite developmentGO:0016358720.012
positive regulation of transportGO:00510502450.012
Rat
response to amineGO:0014075460.012
response to glucoseGO:00097491360.012
embryonic hindlimb morphogenesisGO:003511620.012
saliva secretionGO:004654130.012
positive regulation of lymphocyte proliferationGO:0050671200.012
Rat
regulation of ossificationGO:0030278320.012
motor neuron axon guidanceGO:000804510.012
ion homeostasisGO:00508012120.012
Rat
positive regulation of transferase activityGO:0051347810.012
Human
rna metabolic processGO:00160704060.012
Human
organic acid metabolic processGO:00060822920.012
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.012
cell morphogenesisGO:00009021420.012
feeding behaviorGO:0007631530.012
biological adhesionGO:00226101100.012
Human
peptidyl tyrosine phosphorylationGO:0018108720.012
carbohydrate derivative biosynthetic processGO:19011371240.012
nucleoside metabolic processGO:00091161790.012
regulation of epithelial cell proliferationGO:0050678490.012
negative regulation of cell deathGO:00605482290.012
hormone metabolic processGO:0042445690.011
inorganic ion transmembrane transportGO:00986602290.011
cellular response to corticosteroid stimulusGO:0071384690.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
nucleoside triphosphate metabolic processGO:00091411440.011
salivary gland developmentGO:000743130.011
ribonucleoside metabolic processGO:00091191740.011
cellular response to starvationGO:0009267270.011
mapk cascadeGO:00001651400.011
Human
response to light stimulusGO:0009416520.011
protein modification by small protein conjugationGO:0032446310.011
cation transmembrane transportGO:00986552630.011
positive regulation of cellular biosynthetic processGO:00313282950.011
Human
nucleic acid templated transcriptionGO:00976593790.011
Human
cytoplasmic transportGO:00164821150.011
positive regulation of cellular catabolic processGO:0031331710.011
purine ribonucleotide catabolic processGO:00091541360.011
negative regulation of neuron differentiationGO:0045665620.011
regulation of purine nucleotide catabolic processGO:0033121650.011
purine containing compound biosynthetic processGO:0072522850.011
urinary tract smooth muscle contractionGO:001484840.011
regulation of cell growthGO:0001558850.011
negative regulation of uterine smooth muscle contractionGO:007047320.011
regulation of catabolic processGO:00098941130.011
epithelial cell proliferationGO:0050673540.011
hormone transportGO:00099141210.011
regulation of nucleoside metabolic processGO:0009118660.011
maintenance of locationGO:0051235170.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
positive regulation of cellular amine metabolic processGO:003324030.011
purine nucleoside catabolic processGO:00061521240.011
monovalent inorganic cation transportGO:00156721720.010
response to biotic stimulusGO:00096072260.010
Rat
negative regulation of signalingGO:00230571570.010
regulation of dendrite developmentGO:0050773590.010
regulation of gluconeogenesisGO:000611140.010
purine containing compound catabolic processGO:00725231380.010
autophagic cell deathGO:004810240.010
purine nucleotide catabolic processGO:00061951360.010
transcription from rna polymerase ii promoterGO:00063662520.010
Human
multicellular organismal catabolic processGO:004424320.010
protein modification by small protein conjugation or removalGO:0070647350.010
regulation of secretionGO:00510462240.010
Rat
response to cocaineGO:0042220390.010
cytokine mediated signaling pathwayGO:0019221430.010
Human
single organismal cell cell adhesionGO:0016337420.010
Human
response to heatGO:0009408600.010
female gonad developmentGO:0008585530.010
regulation of nucleotide biosynthetic processGO:0030808470.010
negative regulation of multicellular organismal processGO:00512412030.010
reproductive system developmentGO:00614581280.010
Rat

Tnfsf11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
Human
cardiovascular system diseaseDOID:128700.016
nervous system diseaseDOID:86300.015
musculoskeletal system diseaseDOID:1700.015
Human
connective tissue diseaseDOID:6500.015
Human
vascular diseaseDOID:17800.011
hypertensionDOID:1076300.011
artery diseaseDOID:005082800.011
immune system diseaseDOID:291400.011
bone diseaseDOID:008000100.011
Human
central nervous system diseaseDOID:33100.010