Rattus norvegicus

4 known processes

Tjp2

tight junction protein 2

(Aliases: ZO-2,MGC124724)

Tjp2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure morphogenesisGO:00096532980.108
neuron differentiationGO:00301823680.094
cellular component assemblyGO:00226073600.093
cell projection organizationGO:00300303020.081
cellular component movementGO:00069282480.076
regulation of apoptotic processGO:00429813350.075
protein localizationGO:00081041910.073
macromolecule localizationGO:00330362520.072
organic acid metabolic processGO:00060822920.071
response to metal ionGO:00100382530.069
cellular amino acid metabolic processGO:00065201070.069
protein complex subunit organizationGO:00718223020.067
response to woundingGO:00096112540.063
organophosphate metabolic processGO:00196373700.063
cell motilityGO:00488702020.062
organelle organizationGO:00069962660.061
macromolecular complex subunit organizationGO:00439333390.059
apoptotic processGO:00069153810.058
blood circulationGO:00080151830.058
Rat
response to inorganic substanceGO:00100353770.057
agingGO:00075682410.057
neuron projection developmentGO:00311752730.056
gap junction assemblyGO:001626420.056
regulation of membrane potentialGO:00423911100.055
protein complex biogenesisGO:00702712630.055
response to extracellular stimulusGO:00099913800.055
positive regulation of cell communicationGO:00106472710.054
carboxylic acid metabolic processGO:00197522890.048
macromolecular complex assemblyGO:00650032730.048
regulation of secretionGO:00510462240.047
regulation of cell proliferationGO:00421273590.047
head developmentGO:00603222470.046
regulation of transcription dna templatedGO:00063553740.045
single organism biosynthetic processGO:00447113420.045
cellular component biogenesisGO:00440853680.044
response to oxidative stressGO:00069791860.044
positive regulation of catalytic activityGO:00430851840.044
carbohydrate derivative metabolic processGO:19011353460.043
axon developmentGO:0061564960.043
response to nutrient levelsGO:00316673700.043
mapk cascadeGO:00001651400.043
cellular response to endogenous stimulusGO:00714953770.043
protein heterooligomerizationGO:0051291890.042
circulatory system processGO:00030131830.041
Rat
protein complex assemblyGO:00064612630.040
positive regulation of response to stimulusGO:00485842850.040
cellular response to stressGO:00335542690.039
locomotionGO:00400112370.038
cellular catabolic processGO:00442482950.038
reproductive processGO:00224143720.038
regulation of cellular amine metabolic processGO:003323880.038
positive regulation of signalingGO:00230562700.038
regulation of nucleic acid templated transcriptionGO:19035063800.037
tissue developmentGO:00098882520.037
transcription dna templatedGO:00063513770.037
positive regulation of molecular functionGO:00440932300.037
protein oligomerizationGO:00512591910.037
reproductionGO:00000032450.036
programmed cell deathGO:00125013920.036
oxoacid metabolic processGO:00434362900.036
regulation of system processGO:00440572080.035
neuron developmentGO:00486662860.035
anterior posterior pattern specificationGO:000995210.035
regulation of phosphate metabolic processGO:00192203490.035
rna biosynthetic processGO:00327743800.035
neurological system processGO:00508772190.035
regulation of protein metabolic processGO:00512462890.035
organic anion transportGO:00157111320.035
action potentialGO:0001508540.035
regulation of programmed cell deathGO:00430673410.034
regulation of cellular amino acid metabolic processGO:000652120.034
protein phosphorylationGO:00064683450.034
rna metabolic processGO:00160704060.034
central nervous system developmentGO:00074173110.034
cellular amine metabolic processGO:0044106380.034
positive regulation of phosphate metabolic processGO:00459372620.033
single organism reproductive processGO:00447022970.033
response to estrogenGO:00436272320.033
cell projection morphogenesisGO:00488581230.033
regulation of cellular ketone metabolic processGO:0010565270.032
intracellular signal transductionGO:00355563140.032
negative regulation of metabolic processGO:00098923310.032
positive regulation of cell proliferationGO:00082842490.032
vesicle mediated transportGO:00161921810.032
cell adhesionGO:00071551100.032
regulation of neurogenesisGO:00507672470.031
growthGO:00400071650.031
cellular ketone metabolic processGO:0042180510.031
lipid metabolic processGO:00066292830.031
wound healingGO:00420601220.031
single organism organelle organizationGO:19025891800.031
response to external biotic stimulusGO:00432072210.031
Rat
response to acid chemicalGO:00011012220.030
cell migrationGO:00164771970.030
nucleobase containing small molecule metabolic processGO:00550863160.030
organonitrogen compound biosynthetic processGO:19015661670.030
regulation of nervous system developmentGO:00519602640.030
multicellular organism reproductionGO:00325042330.030
immune system processGO:00023762040.030
regulation of intracellular signal transductionGO:19025312180.030
nitrogen compound transportGO:00717052290.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
epithelium developmentGO:0060429960.030
positive regulation of multicellular organismal processGO:00512403870.029
nucleic acid templated transcriptionGO:00976593790.029
purine nucleotide metabolic processGO:00061632290.029
positive regulation of transportGO:00510502450.029
anion transportGO:00068201780.029
regulation of cellular component organizationGO:00511283680.029
neuronal action potentialGO:0019228350.029
regulation of catalytic activityGO:00507903040.029
transmembrane transportGO:00550854120.028
negative regulation of cell communicationGO:00106481580.028
chemical homeostasisGO:00488782920.028
Rat
cell part morphogenesisGO:00329901230.028
localization of cellGO:00516742020.028
cell morphogenesisGO:00009021420.028
amine metabolic processGO:0009308380.027
response to radiationGO:00093141370.027
axis specificationGO:000979840.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
behaviorGO:00076102050.027
regulation of rna metabolic processGO:00512523910.027
multicellular organismal signalingGO:0035637440.027
positive regulation of biosynthetic processGO:00098913190.027
proteolysisGO:00065081750.026
regulation of transferase activityGO:00513381230.026
purine containing compound metabolic processGO:00725212530.026
secretionGO:00469033070.026
purine ribonucleotide metabolic processGO:00091502270.026
multicellular organismal reproductive processGO:00486092330.026
organic acid transportGO:00158491160.026
positive regulation of phosphorylationGO:00423271770.025
cellular lipid metabolic processGO:00442552080.025
cardiovascular system developmentGO:00723581340.025
multi organism reproductive processGO:00447032620.025
regulation of multicellular organismal developmentGO:20000263760.025
organophosphate biosynthetic processGO:00904071430.025
positive regulation of signal transductionGO:00099671750.025
cation transmembrane transportGO:00986552630.025
regulation of molecular functionGO:00650093980.025
cell morphogenesis involved in neuron differentiationGO:00486671060.025
positive regulation of cellular component organizationGO:00511302000.025
regulation of cell differentiationGO:00455953200.025
biological adhesionGO:00226101100.025
negative regulation of signalingGO:00230571570.025
cardiac conductionGO:006133720.024
cellular response to oxygen containing compoundGO:19017013860.024
Rat
asymmetric protein localizationGO:000810520.024
embryonic pattern specificationGO:000988010.024
synaptic transmissionGO:00072682350.024
heart contractionGO:0060047570.024
response to growth factorGO:00708481890.024
regulation of cell projection organizationGO:00313441750.024
regulation of signal transductionGO:00099663180.024
regulation of rna biosynthetic processGO:20011413810.023
regulation of mapk cascadeGO:00434081160.023
ribonucleotide metabolic processGO:00092592310.023
metaphase anaphase transition of mitotic cell cycleGO:000709110.023
negative regulation of biosynthetic processGO:00098901680.023
brain developmentGO:00074202470.023
rhythmic processGO:00485111560.023
response to toxic substanceGO:00096361330.023
regulation of cellular localizationGO:00603412630.023
response to monosaccharideGO:00342841590.023
Rat
cation transportGO:00068123820.023
negative regulation of cell deathGO:00605482290.023
positive regulation of cellular protein metabolic processGO:00322701670.023
nucleotide metabolic processGO:00091172790.023
ribose phosphate metabolic processGO:00196932350.023
response to nutrientGO:00075842480.023
homeostatic processGO:00425923310.022
Rat
regulation of canonical wnt signaling pathwayGO:006082840.022
cellular component morphogenesisGO:00329891550.022
regulation of secretion by cellGO:19035302080.022
negative regulation of programmed cell deathGO:00430691830.022
ras protein signal transductionGO:0007265290.022
regulation of growthGO:00400081050.022
response to glucocorticoidGO:00513842230.022
regulation of phosphorus metabolic processGO:00511743490.022
cytoskeleton organizationGO:00070101110.021
glycerolipid metabolic processGO:0046486670.021
response to bacteriumGO:00096172000.021
Rat
carboxylic acid transportGO:00469421150.021
cellular response to nitrogen compoundGO:19016992100.021
regulation of anatomical structure morphogenesisGO:00226031410.021
regulation of transcription from rna polymerase ii promoterGO:00063572340.021
ensheathment of neuronsGO:0007272400.020
organonitrogen compound catabolic processGO:19015651790.020
positive regulation of developmental processGO:00510942830.020
negative regulation of response to stimulusGO:00485851550.020
regulation of cell growthGO:0001558850.020
sex differentiationGO:00075481130.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
cell cell signalingGO:00072673350.020
cognitionGO:0050890920.020
positive regulation of gene expressionGO:00106282440.020
cation homeostasisGO:00550801950.020
negative regulation of macromolecule metabolic processGO:00106052600.020
salivary gland morphogenesisGO:000743510.020
membrane organizationGO:0061024940.020
regulation of anatomical structure sizeGO:00900661350.020
catabolic processGO:00090563510.020
negative regulation of cellular metabolic processGO:00313242810.020
positive regulation of intracellular signal transductionGO:19025331380.020
positive regulation of protein phosphorylationGO:00019341350.019
positive regulation of cellular biosynthetic processGO:00313282950.019
response to transition metal nanoparticleGO:19902671220.019
negative regulation of gene expressionGO:00106291990.019
cellular protein localizationGO:00346131220.019
metaphase anaphase transition of cell cycleGO:004478410.019
negative regulation of apoptotic processGO:00430661810.019
regulation of locomotionGO:00400121480.019
cell morphogenesis involved in differentiationGO:00009041190.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
small gtpase mediated signal transductionGO:0007264360.019
organ morphogenesisGO:0009887750.019
synaptic growth at neuromuscular junctionGO:005112410.019
transcription from rna polymerase ii promoterGO:00063662520.019
regulation of phosphorylationGO:00423252480.019
positive regulation of cellular amine metabolic processGO:003324030.019
organic substance catabolic processGO:19015753160.019
single organism membrane organizationGO:0044802740.019
choline transportGO:001587140.018
lipid biosynthetic processGO:00086101280.018
cellular ion homeostasisGO:00068731840.018
organic acid biosynthetic processGO:0016053830.018
myelinationGO:0042552390.018
positive regulation of rna metabolic processGO:00512542030.018
regulation of vesicle mediated transportGO:0060627810.018
response to corticosteroidGO:00319602350.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
cell communication involved in cardiac conductionGO:008606520.018
cellular chemical homeostasisGO:00550822470.018
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
heart processGO:0003015570.018
neuron projection morphogenesisGO:00488121220.018
positive regulation of nervous system developmentGO:00519621780.017
regulation of blood circulationGO:19035221100.017
actin filament depolymerizationGO:003004230.017
establishment of tissue polarityGO:000716420.017
purine ribonucleoside metabolic processGO:00461281680.017
regulation of ion transportGO:00432692450.017
response to vitaminGO:00332731310.017
purine nucleoside metabolic processGO:00422781690.017
establishment of protein localizationGO:00451841410.017
ribonucleoside metabolic processGO:00091191740.017
response to axon injuryGO:0048678590.017
positive regulation of transcription dna templatedGO:00458931970.017
negative regulation of cellular biosynthetic processGO:00313271610.017
cellular homeostasisGO:00197252520.017
Rat
response to ethanolGO:00454711620.017
Rat
cellular response to growth factor stimulusGO:00713631620.017
single organism catabolic processGO:00447122830.017
regulation of cellular component movementGO:00512701500.017
organic cyclic compound catabolic processGO:19013611750.017
positive regulation of rna biosynthetic processGO:19026801970.017
signal transduction by phosphorylationGO:00230141440.016
negative regulation of phosphate metabolic processGO:0045936800.016
response to lipopolysaccharideGO:00324961910.016
Rat
regulation of mitotic sister chromatid separationGO:001096510.016
peptidyl amino acid modificationGO:00181931260.016
gliogenesisGO:0042063930.016
positive regulation of programmed cell deathGO:00430681570.016
embryonic axis specificationGO:000057810.016
phospholipid metabolic processGO:0006644610.016
epithelial cell differentiationGO:0030855710.016
dephosphorylationGO:0016311980.016
coenzyme metabolic processGO:0006732860.016
regulation of catabolic processGO:00098941130.016
cell cycleGO:00070491010.016
response to decreased oxygen levelsGO:00362932370.016
regulation of cell developmentGO:00602842630.016
cellular response to cytokine stimulusGO:00713451270.016
response to mechanical stimulusGO:00096121340.016
response to carbohydrateGO:00097431830.016
Rat
regulation of protein phosphorylationGO:00019321830.016
response to peptideGO:19016522920.016
vascular process in circulatory systemGO:0003018960.016
Rat
positive regulation of cell deathGO:00109421840.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
regulation of cellular protein metabolic processGO:00322682670.016
salivary gland developmentGO:000743130.016
positive regulation of neurogenesisGO:00507691650.016
nucleoside phosphate metabolic processGO:00067532830.016
purine ribonucleotide catabolic processGO:00091541360.015
positive regulation of mapk cascadeGO:0043410920.015
regulation of protein serine threonine kinase activityGO:0071900640.015
response to alkaloidGO:00432791320.015
regulation of neuron differentiationGO:00456642080.015
regulation of protein modification processGO:00313991940.015
positive regulation of cell developmentGO:00107201760.015
negative regulation of transcription dna templatedGO:00458921160.015
cofactor metabolic processGO:0051186950.015
cellular response to organic cyclic compoundGO:00714072020.015
response to estradiolGO:00323551640.015
negative regulation of rna metabolic processGO:00512531230.015
muscle system processGO:00030121150.015
regulation of protein kinase activityGO:00458591050.015
regulation of synaptic transmissionGO:00508041410.015
negative regulation of cellular component organizationGO:0051129830.015
positive regulation of secretionGO:00510471400.015
positive regulation of apoptotic processGO:00430651540.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
positive regulation of phosphorus metabolic processGO:00105622620.015
cellular response to organonitrogen compoundGO:00714171970.015
regulation of neuron projection developmentGO:00109751610.015
cytokinetic processGO:003250610.015
ion transmembrane transportGO:00342203650.015
positive regulation of protein modification processGO:00314011420.015
small molecule biosynthetic processGO:00442831240.015
response to oxygen levelsGO:00704822650.015
response to other organismGO:00517072200.015
Rat
actin filament based processGO:0030029860.015
intracellular transportGO:00469071850.014
cellular nitrogen compound catabolic processGO:00442701630.014
regulation of muscle system processGO:0090257790.014
circulatory system developmentGO:00723591340.014
divalent inorganic cation homeostasisGO:00725071650.014
aromatic compound catabolic processGO:00194391680.014
heart morphogenesisGO:000300730.014
axonogenesisGO:0007409710.014
monovalent inorganic cation transportGO:00156721720.014
inflammatory responseGO:00069541500.014
cellular macromolecule localizationGO:00707271220.014
regulation of mitotic sister chromatid segregationGO:003304710.014
response to hypoxiaGO:00016662310.014
response to amino acidGO:0043200750.014
cellular response to external stimulusGO:00714961180.014
mesoderm developmentGO:000749820.014
negative regulation of multicellular organismal processGO:00512412030.014
protein transportGO:00150311320.014
cellular modified amino acid metabolic processGO:0006575610.014
developmental growthGO:00485891000.014
chromosome segregationGO:000705920.014
glycosyl compound metabolic processGO:19016571820.014
response to hydrogen peroxideGO:0042542890.014
single organism behaviorGO:00447081300.014
nucleoside phosphate biosynthetic processGO:19012931020.014
single organismal cell cell adhesionGO:0016337420.014
axon ensheathmentGO:0008366400.014
cell growthGO:00160491040.014
regulation of response to stressGO:00801341260.014
organic hydroxy compound transportGO:0015850770.014
negative regulation of monooxygenase activityGO:003276930.014
calcium ion homeostasisGO:00550741620.014
single organism cellular localizationGO:19025801020.014
cellular cation homeostasisGO:00300031800.013
transmission of nerve impulseGO:0019226420.013
regulation of blood pressureGO:0008217830.013
rho protein signal transductionGO:0007266110.013
sexual reproductionGO:00199531480.013
defense responseGO:00069521940.013
eye morphogenesisGO:004859240.013
carboxylic acid biosynthetic processGO:0046394830.013
forebrain developmentGO:0030900980.013
positive regulation of cell differentiationGO:00455972170.013
regulation of kinase activityGO:00435491170.013
gonad developmentGO:00084061040.013
negative regulation of actin filament polymerizationGO:003083740.013
organic hydroxy compound metabolic processGO:19016151150.013
cell cell junction organizationGO:0045216200.013
reproductive structure developmentGO:00486081280.013
response to hexoseGO:00097461440.013
Rat
regulation of cell migrationGO:00303341280.013
negative regulation of protein metabolic processGO:00512481140.013
negative regulation of transportGO:00510511360.013
reproductive system developmentGO:00614581280.013
development of primary sexual characteristicsGO:00451371070.013
negative regulation of signal transductionGO:0009968830.013
nucleobase containing compound catabolic processGO:00346551520.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of peptide transportGO:0090087870.013
response to purine containing compoundGO:00140741260.013
heterocycle catabolic processGO:00467001670.013
secretion by cellGO:00329402480.013
positive regulation of transferase activityGO:0051347810.013
regulation of cell morphogenesisGO:0022604770.013
nucleoside metabolic processGO:00091161790.013
regulation of metal ion transportGO:00109591180.013
embryo developmentGO:0009790490.013
regulation of actin filament depolymerizationGO:003083420.013
mitotic sister chromatid separationGO:005130610.013
male sex differentiationGO:0046661640.013
positive regulation of cell motilityGO:2000147970.013
signal releaseGO:00230611450.013
cytosolic calcium ion homeostasisGO:00514801400.013
actin cytoskeleton organizationGO:0030036730.013
chemosensory behaviorGO:000763520.012
hormone transportGO:00099141210.012
regulation of vasculature developmentGO:1901342440.012
negative regulation of macromolecule biosynthetic processGO:00105581480.012
carbohydrate derivative catabolic processGO:19011361470.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
peptidyl tyrosine phosphorylationGO:0018108720.012
cellular response to lipidGO:00713962010.012
regenerationGO:00310991630.012
single organism intracellular transportGO:19025821660.012
inorganic cation transmembrane transportGO:00986622020.012
vasculature developmentGO:0001944700.012
glycosyl compound catabolic processGO:19016581260.012
purine nucleotide catabolic processGO:00061951360.012
neuron projection regenerationGO:0031102350.012
amino acid transportGO:0006865700.012
regulation of hormone secretionGO:00468831060.012
regulation of erk1 and erk2 cascadeGO:0070372410.012
adult locomotory behaviorGO:000834440.012
positive regulation of protein kinase activityGO:0045860730.012
reactive oxygen species biosynthetic processGO:190340980.012
gastrulationGO:000736920.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
b cell differentiationGO:003018320.012
ion homeostasisGO:00508012120.012
regulation of hormone levelsGO:00108171870.012
macromolecule catabolic processGO:0009057580.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
learning or memoryGO:0007611900.012
regulation of immune system processGO:00026821230.012
metal ion homeostasisGO:00550651860.012
response to peptide hormoneGO:00434342780.012
positive regulation of secretion by cellGO:19035321280.012
positive regulation of locomotionGO:00400171020.011
positive regulation of protein serine threonine kinase activityGO:0071902520.011
glial cell differentiationGO:0010001650.011
regulation of tube sizeGO:0035150890.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
positive regulation of cellular component movementGO:00512721020.011
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
cellular response to hormone stimulusGO:00328702470.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
interleukin 12 productionGO:003261530.011
positive regulation of kinase activityGO:0033674770.011
positive regulation of protein metabolic processGO:00512471780.011
alpha amino acid biosynthetic processGO:1901607230.011
amide transportGO:00428861050.011
gamete generationGO:00072761240.011
mitotic spindle organizationGO:000705220.011
protein localization to membraneGO:0072657360.011
reactive oxygen species metabolic processGO:0072593370.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
sensory perceptionGO:00076001010.011
regulation of neuron apoptotic processGO:0043523830.011
regulation of homeostatic processGO:00328441010.011
lipid transportGO:0006869610.011
cytoplasmic transportGO:00164821150.011
nucleoside triphosphate metabolic processGO:00091411440.011
regulation of organelle organizationGO:0033043800.011
response to biotic stimulusGO:00096072260.011
Rat
regulation of blood vessel sizeGO:0050880890.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
developmental process involved in reproductionGO:00030061590.011
intracellular protein transportGO:0006886790.011
activation of protein kinase activityGO:0032147470.011
purine containing compound biosynthetic processGO:0072522850.011
response to insulinGO:00328681330.011
spindle organizationGO:000705120.011
multicellular organism growthGO:003526410.011
cellular calcium ion homeostasisGO:00068741600.011
response to temperature stimulusGO:0009266940.011
regulation of nucleotide metabolic processGO:00061401170.011
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.011
morphogenesis of a polarized epitheliumGO:000173810.011
glycerophospholipid metabolic processGO:0006650470.011
development of primary male sexual characteristicsGO:0046546590.011
cellular amino acid biosynthetic processGO:0008652320.011
regulation of cellular component biogenesisGO:0044087860.011
response to cytokineGO:00340972150.011
neuron deathGO:00709971270.011
regulation of cell motilityGO:20001451310.011
negative regulation of nervous system developmentGO:0051961790.011
purine nucleoside catabolic processGO:00061521240.011
oxidation reduction processGO:00551143040.010
cellular metal ion homeostasisGO:00068751720.010
cellular response to extracellular stimulusGO:0031668730.010
negative regulation of cellular protein metabolic processGO:00322691060.010
blood vessel morphogenesisGO:0048514580.010
g protein coupled receptor signaling pathwayGO:00071862420.010
response to ketoneGO:19016541820.010
single organism carbohydrate metabolic processGO:00447231180.010
neuromuscular synaptic transmissionGO:000727420.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
hematopoietic progenitor cell differentiationGO:000224420.010
neural crest cell developmentGO:001403220.010

Tjp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.019
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
Human
musculoskeletal system diseaseDOID:1700.014
cardiovascular system diseaseDOID:128700.013
muscular diseaseDOID:008000000.011
eye diseaseDOID:561400.011
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011