Rattus norvegicus

0 known processes

Nek4

NIMA (never in mitosis gene a)-related kinase 4

Nek4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.071
nucleic acid templated transcriptionGO:00976593790.067
rna biosynthetic processGO:00327743800.064
regulation of transcription dna templatedGO:00063553740.062
transcription dna templatedGO:00063513770.060
regulation of nucleic acid templated transcriptionGO:19035063800.054
regulation of rna biosynthetic processGO:20011413810.052
regulation of rna metabolic processGO:00512523910.050
regulation of apoptotic processGO:00429813350.049
programmed cell deathGO:00125013920.049
cellular amino acid metabolic processGO:00065201070.047
regulation of cell proliferationGO:00421273590.047
response to inorganic substanceGO:00100353770.046
positive regulation of nitrogen compound metabolic processGO:00511733340.046
positive regulation of nucleobase containing compound metabolic processGO:00459353190.046
intracellular signal transductionGO:00355563140.045
cellular response to oxygen containing compoundGO:19017013860.044
cellular ketone metabolic processGO:0042180510.043
positive regulation of cellular biosynthetic processGO:00313282950.043
regulation of programmed cell deathGO:00430673410.041
positive regulation of rna metabolic processGO:00512542030.041
negative regulation of metabolic processGO:00098923310.040
amine metabolic processGO:0009308380.039
positive regulation of biosynthetic processGO:00098913190.038
neurological system processGO:00508772190.037
regulation of cellular amine metabolic processGO:003323880.036
organic substance catabolic processGO:19015753160.036
single organism catabolic processGO:00447122830.036
organic acid metabolic processGO:00060822920.036
regulation of molecular functionGO:00650093980.035
regulation of phosphate metabolic processGO:00192203490.035
response to extracellular stimulusGO:00099913800.034
cell cell signalingGO:00072673350.034
regulation of cellular amino acid metabolic processGO:000652120.034
regulation of phosphorus metabolic processGO:00511743490.034
carboxylic acid metabolic processGO:00197522890.033
regulation of cellular localizationGO:00603412630.032
regulation of signal transductionGO:00099663180.032
positive regulation of rna biosynthetic processGO:19026801970.031
cellular component assemblyGO:00226073600.031
positive regulation of multicellular organismal processGO:00512403870.031
neuron projection developmentGO:00311752730.031
regulation of cellular ketone metabolic processGO:0010565270.030
regulation of transcription from rna polymerase ii promoterGO:00063572340.030
oxoacid metabolic processGO:00434362900.030
positive regulation of response to stimulusGO:00485842850.030
nitrogen compound transportGO:00717052290.030
cellular response to endogenous stimulusGO:00714953770.030
multicellular organism reproductionGO:00325042330.030
negative regulation of macromolecule metabolic processGO:00106052600.030
neuron developmentGO:00486662860.029
apoptotic processGO:00069153810.029
cellular amine metabolic processGO:0044106380.029
reproductive processGO:00224143720.029
organelle organizationGO:00069962660.029
neuron differentiationGO:00301823680.029
transcription from rna polymerase ii promoterGO:00063662520.029
catabolic processGO:00090563510.029
positive regulation of transcription dna templatedGO:00458931970.028
positive regulation of macromolecule biosynthetic processGO:00105572470.028
chemical homeostasisGO:00488782920.028
macromolecule localizationGO:00330362520.028
negative regulation of cellular metabolic processGO:00313242810.028
positive regulation of cell proliferationGO:00082842490.028
positive regulation of cell differentiationGO:00455972170.028
negative regulation of nitrogen compound metabolic processGO:00511721610.027
single organism organelle organizationGO:19025891800.027
homeostatic processGO:00425923310.027
cation transportGO:00068123820.027
regulation of multicellular organismal developmentGO:20000263760.027
response to growth factorGO:00708481890.027
positive regulation of signalingGO:00230562700.027
regulation of phosphorylationGO:00423252480.027
multi organism reproductive processGO:00447032620.027
protein phosphorylationGO:00064683450.027
Mouse
secretionGO:00469033070.027
negative regulation of gene expressionGO:00106291990.027
cellular component movementGO:00069282480.027
secretion by cellGO:00329402480.027
tissue developmentGO:00098882520.026
cellular catabolic processGO:00442482950.026
positive regulation of gene expressionGO:00106282440.026
positive regulation of cell communicationGO:00106472710.026
cellular homeostasisGO:00197252520.026
brain developmentGO:00074202470.026
regulation of cell developmentGO:00602842630.026
protein localizationGO:00081041910.026
single organism biosynthetic processGO:00447113420.026
agingGO:00075682410.026
Human
head developmentGO:00603222470.026
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.025
regulation of cell differentiationGO:00455953200.025
regulation of protein modification processGO:00313991940.025
response to metal ionGO:00100382530.025
negative regulation of signalingGO:00230571570.025
negative regulation of multicellular organismal processGO:00512412030.025
central nervous system developmentGO:00074173110.024
behaviorGO:00076102050.024
regulation of nervous system developmentGO:00519602640.024
regulation of intracellular signal transductionGO:19025312180.024
single organism reproductive processGO:00447022970.024
nucleoside phosphate metabolic processGO:00067532830.024
carbohydrate derivative metabolic processGO:19011353460.024
anterior posterior pattern specificationGO:000995210.023
response to woundingGO:00096112540.023
positive regulation of cellular amine metabolic processGO:003324030.023
regulation of neurogenesisGO:00507672470.023
purine containing compound metabolic processGO:00725212530.023
establishment of protein localizationGO:00451841410.023
multicellular organismal reproductive processGO:00486092330.023
negative regulation of biosynthetic processGO:00098901680.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
negative regulation of cell communicationGO:00106481580.023
positive regulation of transportGO:00510502450.022
positive regulation of phosphorus metabolic processGO:00105622620.022
regulation of protein metabolic processGO:00512462890.022
chromosome segregationGO:000705920.022
positive regulation of signal transductionGO:00099671750.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
positive regulation of nervous system developmentGO:00519621780.022
regulation of synaptic transmissionGO:00508041410.022
cell motilityGO:00488702020.021
response to oxidative stressGO:00069791860.021
regulation of cellular component organizationGO:00511283680.021
regulation of cellular protein metabolic processGO:00322682670.021
positive regulation of cellular component organizationGO:00511302000.021
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
response to alkaloidGO:00432791320.021
nucleotide metabolic processGO:00091172790.021
organophosphate metabolic processGO:00196373700.021
response to carbohydrateGO:00097431830.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
macromolecular complex subunit organizationGO:00439333390.021
nucleobase containing small molecule metabolic processGO:00550863160.021
reproductionGO:00000032450.021
regulation of neuron differentiationGO:00456642080.021
anatomical structure morphogenesisGO:00096532980.021
response to nutrient levelsGO:00316673700.021
negative regulation of programmed cell deathGO:00430691830.020
cellular component biogenesisGO:00440853680.020
negative regulation of molecular functionGO:00440921330.020
regulation of catalytic activityGO:00507903040.020
circulatory system processGO:00030131830.020
positive regulation of phosphate metabolic processGO:00459372620.020
positive regulation of developmental processGO:00510942830.020
cellular response to stressGO:00335542690.020
Human
regulation of secretion by cellGO:19035302080.020
regulation of secretionGO:00510462240.020
cell projection organizationGO:00300303020.020
synaptic growth at neuromuscular junctionGO:005112410.020
negative regulation of cell deathGO:00605482290.019
negative regulation of nucleic acid templated transcriptionGO:19035071170.019
response to hypoxiaGO:00016662310.019
regulation of hormone levelsGO:00108171870.019
metal ion homeostasisGO:00550651860.019
protein complex subunit organizationGO:00718223020.019
negative regulation of response to stimulusGO:00485851550.019
cell migrationGO:00164771970.019
positive regulation of neuron differentiationGO:00456661260.019
positive regulation of neurogenesisGO:00507691650.019
synaptic transmissionGO:00072682350.019
negative regulation of rna metabolic processGO:00512531230.018
ribonucleotide catabolic processGO:00092611360.018
cellular divalent inorganic cation homeostasisGO:00725031620.018
developmental process involved in reproductionGO:00030061590.018
regulation of hydrolase activityGO:00513361430.018
positive regulation of protein metabolic processGO:00512471780.018
lipid metabolic processGO:00066292830.018
response to mechanical stimulusGO:00096121340.018
single organism behaviorGO:00447081300.018
regulation of cell cycleGO:0051726730.018
negative regulation of developmental processGO:00510931250.018
response to estrogenGO:00436272320.018
signal releaseGO:00230611450.018
positive regulation of molecular functionGO:00440932300.018
negative regulation of transcription dna templatedGO:00458921160.018
cellular macromolecule localizationGO:00707271220.018
response to peptideGO:19016522920.017
regulation of cell motilityGO:20001451310.017
positive regulation of cell developmentGO:00107201760.017
response to toxic substanceGO:00096361330.017
negative regulation of cellular biosynthetic processGO:00313271610.017
purine ribonucleotide metabolic processGO:00091502270.017
regulation of membrane potentialGO:00423911100.017
cellular protein localizationGO:00346131220.017
response to acid chemicalGO:00011012220.017
single organism intracellular transportGO:19025821660.017
embryonic skeletal system developmentGO:004870630.017
response to glucocorticoidGO:00513842230.017
response to reactive oxygen speciesGO:00003021200.017
single organism cellular localizationGO:19025801020.017
immune system processGO:00023762040.017
localization of cellGO:00516742020.017
response to decreased oxygen levelsGO:00362932370.017
cell cycleGO:00070491010.017
Human
positive regulation of cell deathGO:00109421840.017
cell morphogenesisGO:00009021420.017
cellular metal ion homeostasisGO:00068751720.016
ribonucleotide metabolic processGO:00092592310.016
cellular response to nitrogen compoundGO:19016992100.016
macromolecular complex assemblyGO:00650032730.016
negative regulation of transportGO:00510511360.016
purine nucleotide metabolic processGO:00061632290.016
eye morphogenesisGO:004859240.016
multi multicellular organism processGO:00447061380.016
positive regulation of secretionGO:00510471400.016
ribose phosphate metabolic processGO:00196932350.016
response to nutrientGO:00075842480.016
regulation of system processGO:00440572080.016
ion transmembrane transportGO:00342203650.016
sexual reproductionGO:00199531480.016
positive regulation of intracellular signal transductionGO:19025331380.016
growthGO:00400071650.016
response to biotic stimulusGO:00096072260.016
organ regenerationGO:00311001010.016
cellular cation homeostasisGO:00300031800.016
response to estradiolGO:00323551640.016
regenerationGO:00310991630.016
response to glucoseGO:00097491360.016
regulation of peptide transportGO:0090087870.016
negative regulation of cell proliferationGO:00082851190.016
g protein coupled receptor signaling pathwayGO:00071862420.015
response to monosaccharideGO:00342841590.015
regulation of cellular catabolic processGO:00313291010.015
response to external biotic stimulusGO:00432072210.015
protein complex assemblyGO:00064612630.015
cytosolic calcium ion homeostasisGO:00514801400.015
cellular calcium ion homeostasisGO:00068741600.015
response to other organismGO:00517072200.015
heterocycle catabolic processGO:00467001670.015
response to molecule of bacterial originGO:00022371940.015
carbohydrate metabolic processGO:00059751300.015
regulation of response to external stimulusGO:00321011060.015
positive regulation of phosphorylationGO:00423271770.015
gastrulationGO:000736920.015
cellular response to growth factor stimulusGO:00713631620.015
locomotionGO:00400112370.015
response to peptide hormoneGO:00434342780.015
organonitrogen compound biosynthetic processGO:19015661670.015
gamete generationGO:00072761240.015
regulation of anatomical structure sizeGO:00900661350.015
response to bacteriumGO:00096172000.015
axon developmentGO:0061564960.015
actin filament based processGO:0030029860.015
bmp signaling pathwayGO:003050940.015
cellular response to organic cyclic compoundGO:00714072020.015
negative regulation of apoptotic processGO:00430661810.015
cellular chemical homeostasisGO:00550822470.014
regulation of response to stressGO:00801341260.014
Human
negative regulation of rna biosynthetic processGO:19026791180.014
hormone secretionGO:00468791150.014
positive regulation of cellular protein metabolic processGO:00322701670.014
positive regulation of apoptotic processGO:00430651540.014
cation homeostasisGO:00550801950.014
cellular response to hormone stimulusGO:00328702470.014
positive regulation of protein phosphorylationGO:00019341350.014
ion homeostasisGO:00508012120.014
response to oxygen levelsGO:00704822650.014
gland developmentGO:00487321550.014
sex differentiationGO:00075481130.014
divalent inorganic cation homeostasisGO:00725071650.014
cellular lipid metabolic processGO:00442552080.014
blood circulationGO:00080151830.014
regulation of protein phosphorylationGO:00019321830.014
protein transportGO:00150311320.014
axis specificationGO:000979840.014
positive regulation of protein modification processGO:00314011420.014
salivary gland developmentGO:000743130.014
small gtpase mediated signal transductionGO:0007264360.014
positive regulation of secretion by cellGO:19035321280.014
regulation of organelle organizationGO:0033043800.014
positive regulation of programmed cell deathGO:00430681570.014
nucleoside metabolic processGO:00091161790.014
purine nucleoside catabolic processGO:00061521240.014
cytoplasmic transportGO:00164821150.013
response to hexoseGO:00097461440.013
calcium ion homeostasisGO:00550741620.013
ras protein signal transductionGO:0007265290.013
regulation of cell projection organizationGO:00313441750.013
protein complex biogenesisGO:00702712630.013
cell morphogenesis involved in differentiationGO:00009041190.013
metal ion transportGO:00300012890.013
purine ribonucleotide catabolic processGO:00091541360.013
regulation of nucleotide metabolic processGO:00061401170.013
cellular response to organonitrogen compoundGO:00714171970.013
cellular response to external stimulusGO:00714961180.013
regulation of cellular component movementGO:00512701500.013
response to transition metal nanoparticleGO:19902671220.013
cell type specific apoptotic processGO:00972851340.013
nucleoside phosphate catabolic processGO:19012921400.013
embryonic pattern specificationGO:000988010.013
positive regulation of catalytic activityGO:00430851840.013
reproductive system developmentGO:00614581280.013
response to ethanolGO:00454711620.013
cellular ion homeostasisGO:00068731840.013
negative regulation of innate immune responseGO:004582440.013
regulation of kinase activityGO:00435491170.013
negative regulation of cell differentiationGO:0045596990.013
sensory organ developmentGO:0007423740.013
response to radiationGO:00093141370.013
single organism carbohydrate metabolic processGO:00447231180.013
organic cyclic compound catabolic processGO:19013611750.013
aromatic compound catabolic processGO:00194391680.013
cellular response to peptideGO:19016531330.013
peptidyl amino acid modificationGO:00181931260.013
negative regulation of signal transductionGO:0009968830.013
carbohydrate derivative biosynthetic processGO:19011371240.013
peptide secretionGO:0002790860.012
nucleoside phosphate biosynthetic processGO:19012931020.012
cytoskeleton organizationGO:00070101110.012
cell projection morphogenesisGO:00488581230.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
glycosyl compound metabolic processGO:19016571820.012
response to hydrogen peroxideGO:0042542890.012
muscle structure developmentGO:0061061870.012
positive regulation of cell projection organizationGO:00313461110.012
cellular nitrogen compound catabolic processGO:00442701630.012
proteolysisGO:00065081750.012
ribonucleoside metabolic processGO:00091191740.012
development of primary sexual characteristicsGO:00451371070.012
developmental growthGO:00485891000.012
regulation of tube sizeGO:0035150890.012
monovalent inorganic cation transportGO:00156721720.012
divalent inorganic cation transportGO:00725111340.012
regulation of mapk cascadeGO:00434081160.012
regulation of transferase activityGO:00513381230.012
mapk cascadeGO:00001651400.012
regulation of neuron projection developmentGO:00109751610.012
reproductive structure developmentGO:00486081280.012
glycosyl compound catabolic processGO:19016581260.012
response to ketoneGO:19016541820.012
regulation of catabolic processGO:00098941130.012
ribonucleoside catabolic processGO:00424541260.012
dephosphorylationGO:0016311980.012
signal transduction by phosphorylationGO:00230141440.012
nucleobase containing compound catabolic processGO:00346551520.012
organonitrogen compound catabolic processGO:19015651790.012
regulation of hormone secretionGO:00468831060.012
response to vitaminGO:00332731310.012
limb morphogenesisGO:003510840.012
female pregnancyGO:00075651220.012
intracellular protein transportGO:0006886790.012
sensory perceptionGO:00076001010.012
protein localization to organelleGO:0033365570.012
regulation of blood circulationGO:19035221100.012
response to lipopolysaccharideGO:00324961910.011
oxidation reduction processGO:00551143040.011
gonad developmentGO:00084061040.011
cellular response to lipidGO:00713962010.011
cell part morphogenesisGO:00329901230.011
cell cycle processGO:0022402570.011
peptide transportGO:0015833970.011
regulation of locomotionGO:00400121480.011
regulation of peptide hormone secretionGO:0090276800.011
neuron projection morphogenesisGO:00488121220.011
mesoderm developmentGO:000749820.011
cell growthGO:00160491040.011
spermatogenesisGO:0007283990.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
heart morphogenesisGO:000300730.011
positive regulation of mapk cascadeGO:0043410920.011
regulation of cell migrationGO:00303341280.011
intracellular transportGO:00469071850.011
negative regulation of cell cycle phase transitionGO:190198840.011
purine nucleoside metabolic processGO:00422781690.011
circulatory system developmentGO:00723591340.011
positive regulation of nucleotide metabolic processGO:0045981910.011
negative regulation of cellular component organizationGO:0051129830.011
male gamete generationGO:0048232990.011
response to corticosteroidGO:00319602350.011
reactive nitrogen species metabolic processGO:200105710.011
purine ribonucleoside catabolic processGO:00461301240.011
monocarboxylic acid metabolic processGO:00327871520.011
defense responseGO:00069521940.011
embryonic skeletal system morphogenesisGO:004870430.011
positive regulation of kinase activityGO:0033674770.011
negative regulation of protein metabolic processGO:00512481140.011
cellular response to extracellular stimulusGO:0031668730.011
regulation of protein transportGO:0051223680.011
multicellular organism growthGO:003526410.011
maintenance of locationGO:0051235170.011
peptide hormone secretionGO:0030072840.011
ribonucleotide biosynthetic processGO:0009260850.011
negative regulation of catalytic activityGO:00430861030.011
regulation of response to woundingGO:1903034690.011
peptidyl tyrosine phosphorylationGO:0018108720.010
sequestering of metal ionGO:005123890.010
lipid storageGO:001991510.010
mitotic spindle organizationGO:000705220.010
regulation of meiotic cell cycleGO:005144530.010
amide transportGO:00428861050.010
positive regulation of neuron projection developmentGO:0010976990.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
hepaticobiliary system developmentGO:0061008900.010
cardiovascular system developmentGO:00723581340.010
translationGO:0006412350.010
cell cycle checkpointGO:000007520.010
tube formationGO:003514830.010
sister chromatid segregationGO:000081910.010
tube developmentGO:0035295890.010
cellular response to cytokine stimulusGO:00713451270.010
transmembrane transportGO:00550854120.010
cell morphogenesis involved in neuron differentiationGO:00486671060.010
regulation of blood vessel sizeGO:0050880890.010
divalent metal ion transportGO:00708381320.010
purine containing compound catabolic processGO:00725231380.010
rhythmic processGO:00485111560.010
camera type eye morphogenesisGO:004859320.010

Nek4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
musculoskeletal system diseaseDOID:1700.013
sensory system diseaseDOID:005015500.012
connective tissue diseaseDOID:6500.012