Rattus norvegicus

11 known processes

Speg

SPEG complex locus

(Aliases: APEG-1,Apeg1)

Speg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.098
anatomical structure morphogenesisGO:00096532980.089
Worm
neuron developmentGO:00486662860.086
neuron projection developmentGO:00311752730.082
response to woundingGO:00096112540.070
regulation of multicellular organismal developmentGO:20000263760.069
regulation of establishment of planar polarityGO:009017520.067
protein complex subunit organizationGO:00718223020.066
Worm
regulation of phosphorus metabolic processGO:00511743490.066
Worm
macromolecular complex assemblyGO:00650032730.066
Worm
regulation of phosphate metabolic processGO:00192203490.065
Worm
regulation of cell differentiationGO:00455953200.061
regulation of signal transductionGO:00099663180.060
Worm
organic substance catabolic processGO:19015753160.059
Worm
regulation of transcription dna templatedGO:00063553740.059
regulation of cell developmentGO:00602842630.056
positive regulation of multicellular organismal processGO:00512403870.056
protein complex assemblyGO:00064612630.055
Worm
regulation of nucleic acid templated transcriptionGO:19035063800.052
cell projection morphogenesisGO:00488581230.050
macromolecular complex subunit organizationGO:00439333390.050
Worm
rna metabolic processGO:00160704060.050
positive regulation of nitrogen compound metabolic processGO:00511733340.049
Worm
cellular component biogenesisGO:00440853680.049
Worm
protein phosphorylationGO:00064683450.049
catabolic processGO:00090563510.047
Worm
positive regulation of molecular functionGO:00440932300.047
Worm
wnt signaling pathway planar cell polarity pathwayGO:006007120.045
response to oxygen levelsGO:00704822650.045
response to inorganic substanceGO:00100353770.043
regulation of cell proliferationGO:00421273590.043
negative regulation of developmental processGO:00510931250.043
regulation of cellular component organizationGO:00511283680.043
protein oligomerizationGO:00512591910.042
cellular response to oxygen containing compoundGO:19017013860.042
protein complex biogenesisGO:00702712630.042
Worm
ion homeostasisGO:00508012120.041
rna biosynthetic processGO:00327743800.040
cellular component morphogenesisGO:00329891550.040
Worm
secretionGO:00469033070.040
cellular catabolic processGO:00442482950.040
Worm
regulation of catalytic activityGO:00507903040.040
Worm
cellular homeostasisGO:00197252520.039
carbohydrate derivative metabolic processGO:19011353460.039
Worm
reproductive processGO:00224143720.039
response to corticosteroidGO:00319602350.039
regulation of protein metabolic processGO:00512462890.038
cellular cation homeostasisGO:00300031800.038
cell morphogenesisGO:00009021420.038
nucleobase containing small molecule metabolic processGO:00550863160.038
Worm
negative regulation of metabolic processGO:00098923310.038
neuron projection morphogenesisGO:00488121220.037
nucleotide metabolic processGO:00091172790.037
Worm
regulation of cellular protein metabolic processGO:00322682670.037
cellular component assemblyGO:00226073600.036
Worm
homeostatic processGO:00425923310.036
positive regulation of cell proliferationGO:00082842490.036
heart morphogenesisGO:000300730.036
response to metal ionGO:00100382530.036
negative regulation of nitrogen compound metabolic processGO:00511721610.036
carbohydrate metabolic processGO:00059751300.036
multi organism reproductive processGO:00447032620.035
response to estradiolGO:00323551640.035
regulation of neurogenesisGO:00507672470.034
cell projection organizationGO:00300303020.034
positive regulation of response to stimulusGO:00485842850.034
programmed cell deathGO:00125013920.034
positive regulation of developmental processGO:00510942830.033
positive regulation of phosphate metabolic processGO:00459372620.033
Worm
cellular chemical homeostasisGO:00550822470.033
establishment of tissue polarityGO:000716420.033
organic acid metabolic processGO:00060822920.033
regulation of cellular amine metabolic processGO:003323880.033
regulation of neuron differentiationGO:00456642080.033
negative regulation of cell proliferationGO:00082851190.032
intracellular signal transductionGO:00355563140.032
regulation of rna metabolic processGO:00512523910.032
oxoacid metabolic processGO:00434362900.032
locomotionGO:00400112370.032
Worm
negative regulation of multicellular organismal processGO:00512412030.032
regulation of system processGO:00440572080.032
positive regulation of cellular biosynthetic processGO:00313282950.032
single organism organelle organizationGO:19025891800.031
Worm
nucleoside phosphate metabolic processGO:00067532830.031
Worm
regulation of intracellular signal transductionGO:19025312180.031
Worm
regulation of secretionGO:00510462240.031
regulation of cellular amino acid metabolic processGO:000652120.031
organonitrogen compound catabolic processGO:19015651790.030
Worm
nucleic acid templated transcriptionGO:00976593790.030
multicellular organismal reproductive processGO:00486092330.029
wound healingGO:00420601220.029
cell morphogenesis involved in differentiationGO:00009041190.029
positive regulation of cell differentiationGO:00455972170.029
positive regulation of phosphorus metabolic processGO:00105622620.029
Worm
single organism reproductive processGO:00447022970.028
cellular response to lipidGO:00713962010.028
axon developmentGO:0061564960.028
positive regulation of rna metabolic processGO:00512542030.028
reproductionGO:00000032450.027
cell part morphogenesisGO:00329901230.027
chemical homeostasisGO:00488782920.027
regulation of nervous system developmentGO:00519602640.027
positive regulation of signalingGO:00230562700.027
regulation of molecular functionGO:00650093980.027
Worm
single organism catabolic processGO:00447122830.027
Worm
single organism carbohydrate metabolic processGO:00447231180.027
cellular component movementGO:00069282480.027
cellular ketone metabolic processGO:0042180510.027
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
response to glucocorticoidGO:00513842230.026
response to peptideGO:19016522920.026
cellular response to stressGO:00335542690.026
cellular response to organic cyclic compoundGO:00714072020.026
organelle organizationGO:00069962660.026
Worm
cellular response to endogenous stimulusGO:00714953770.026
response to hypoxiaGO:00016662310.026
regulation of cellular localizationGO:00603412630.026
cellular divalent inorganic cation homeostasisGO:00725031620.025
tissue developmentGO:00098882520.025
Mouse
response to nutrient levelsGO:00316673700.025
response to estrogenGO:00436272320.025
negative regulation of macromolecule metabolic processGO:00106052600.025
response to acid chemicalGO:00011012220.025
circulatory system processGO:00030131830.025
response to growth factorGO:00708481890.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
regulation of membrane potentialGO:00423911100.025
positive regulation of biosynthetic processGO:00098913190.025
regulation of anatomical structure morphogenesisGO:00226031410.025
ribose phosphate metabolic processGO:00196932350.025
Worm
regulation of secretion by cellGO:19035302080.025
central nervous system developmentGO:00074173110.024
transcription from rna polymerase ii promoterGO:00063662520.024
embryonic appendage morphogenesisGO:003511340.024
regulation of transcription from rna polymerase ii promoterGO:00063572340.024
cellular metal ion homeostasisGO:00068751720.024
positive regulation of cell communicationGO:00106472710.024
regulation of cellular ketone metabolic processGO:0010565270.024
cellular response to growth factor stimulusGO:00713631620.024
cation homeostasisGO:00550801950.024
regulation of phosphorylationGO:00423252480.023
regulation of neuron projection developmentGO:00109751610.023
cellular nitrogen compound catabolic processGO:00442701630.023
Worm
response to carbohydrateGO:00097431830.023
negative regulation of cell differentiationGO:0045596990.023
cell morphogenesis involved in neuron differentiationGO:00486671060.023
sexual reproductionGO:00199531480.023
cellular response to external stimulusGO:00714961180.023
agingGO:00075682410.023
positive regulation of gene expressionGO:00106282440.023
carboxylic acid metabolic processGO:00197522890.022
positive regulation of transcription dna templatedGO:00458931970.022
regenerationGO:00310991630.022
regulation of protein phosphorylationGO:00019321830.022
cellular ion homeostasisGO:00068731840.022
transcription dna templatedGO:00063513770.022
response to peptide hormoneGO:00434342780.022
single organism biosynthetic processGO:00447113420.022
positive regulation of transportGO:00510502450.022
ribonucleotide metabolic processGO:00092592310.022
Worm
protein localizationGO:00081041910.022
regulation of rna biosynthetic processGO:20011413810.022
response to nutrientGO:00075842480.022
cellular amine metabolic processGO:0044106380.021
regulation of cell projection organizationGO:00313441750.021
metal ion homeostasisGO:00550651860.021
secretion by cellGO:00329402480.021
divalent inorganic cation homeostasisGO:00725071650.021
calcium ion homeostasisGO:00550741620.020
cellular amino acid metabolic processGO:00065201070.020
cell cell signalingGO:00072673350.020
response to decreased oxygen levelsGO:00362932370.020
cardiovascular system developmentGO:00723581340.020
Mouse
axis specificationGO:000979840.020
growthGO:00400071650.020
purine containing compound metabolic processGO:00725212530.020
Worm
purine nucleotide metabolic processGO:00061632290.020
Worm
response to extracellular stimulusGO:00099913800.020
cellular calcium ion homeostasisGO:00068741600.020
cardiac chamber developmentGO:000320510.020
urogenital system developmentGO:0001655780.019
positive regulation of phosphorylationGO:00423271770.019
dephosphorylationGO:0016311980.019
positive regulation of nervous system developmentGO:00519621780.019
positive regulation of signal transductionGO:00099671750.019
response to oxidative stressGO:00069791860.019
negative regulation of nervous system developmentGO:0051961790.019
muscle contractionGO:0006936880.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
Worm
cell migrationGO:00164771970.019
localization of cellGO:00516742020.019
purine ribonucleotide metabolic processGO:00091502270.019
Worm
embryonic pattern specificationGO:000988010.019
neurological system processGO:00508772190.019
purine nucleoside metabolic processGO:00422781690.018
Worm
anterior posterior pattern specificationGO:000995210.018
cellular response to hormone stimulusGO:00328702470.018
positive regulation of protein phosphorylationGO:00019341350.018
synaptic transmissionGO:00072682350.018
positive regulation of cell developmentGO:00107201760.018
negative regulation of cellular metabolic processGO:00313242810.018
regulation of purine nucleotide metabolic processGO:19005421150.018
Worm
cation transportGO:00068123820.018
blood circulationGO:00080151830.018
cell motilityGO:00488702020.018
single organism behaviorGO:00447081300.018
axonogenesisGO:0007409710.018
positive regulation of neurogenesisGO:00507691650.018
negative regulation of biosynthetic processGO:00098901680.018
apoptotic processGO:00069153810.018
kidney developmentGO:0001822670.018
response to transition metal nanoparticleGO:19902671220.017
regulation of anatomical structure sizeGO:00900661350.017
cellular response to nitrogen compoundGO:19016992100.017
signal transduction by phosphorylationGO:00230141440.017
amine metabolic processGO:0009308380.017
single organism cell adhesionGO:0098602460.017
cellular response to organonitrogen compoundGO:00714171970.017
aromatic compound catabolic processGO:00194391680.017
Worm
response to monosaccharideGO:00342841590.017
response to molecule of bacterial originGO:00022371940.017
muscle system processGO:00030121150.017
positive regulation of catalytic activityGO:00430851840.017
Worm
gamete generationGO:00072761240.017
carbohydrate derivative catabolic processGO:19011361470.017
Worm
renal system developmentGO:0072001670.017
regulation of protein modification processGO:00313991940.016
circulatory system developmentGO:00723591340.016
Mouse
response to lipopolysaccharideGO:00324961910.016
positive regulation of cell deathGO:00109421840.016
regulation of hormone levelsGO:00108171870.016
response to ketoneGO:19016541820.016
response to ethanolGO:00454711620.016
positive regulation of rna biosynthetic processGO:19026801970.016
brain developmentGO:00074202470.016
chromosome segregationGO:000705920.016
head developmentGO:00603222470.016
limb morphogenesisGO:003510840.016
reproductive structure developmentGO:00486081280.016
bmp signaling pathwayGO:003050940.016
response to cytokineGO:00340972150.016
response to reactive oxygen speciesGO:00003021200.016
positive regulation of secretion by cellGO:19035321280.016
heart developmentGO:0007507720.015
Mouse
response to glucoseGO:00097491360.015
proteolysisGO:00065081750.015
muscle structure developmentGO:0061061870.015
lipid metabolic processGO:00066292830.015
response to bacteriumGO:00096172000.015
cytosolic calcium ion homeostasisGO:00514801400.015
cellular amide metabolic processGO:0043603440.015
cellular response to peptideGO:19016531330.015
regulation of hydrolase activityGO:00513361430.015
Worm
purine nucleoside triphosphate metabolic processGO:00091441410.015
Worm
negative regulation of response to stimulusGO:00485851550.015
regulation of fat cell differentiationGO:004559830.015
gland developmentGO:00487321550.015
response to axon injuryGO:0048678590.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
Worm
negative regulation of cellular biosynthetic processGO:00313271610.015
positive regulation of apoptotic processGO:00430651540.015
intracellular transportGO:00469071850.015
small gtpase mediated signal transductionGO:0007264360.015
behaviorGO:00076102050.014
action potentialGO:0001508540.014
vesicle mediated transportGO:00161921810.014
cellular lipid metabolic processGO:00442552080.014
positive regulation of cellular protein metabolic processGO:00322701670.014
negative regulation of gene expressionGO:00106291990.014
organic cyclic compound catabolic processGO:19013611750.014
Worm
signal releaseGO:00230611450.014
macromolecule localizationGO:00330362520.014
response to external biotic stimulusGO:00432072210.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
developmental growthGO:00485891000.014
protein transportGO:00150311320.014
morphogenesis of a polarized epitheliumGO:000173810.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
appendage morphogenesisGO:003510740.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
biological adhesionGO:00226101100.014
regulation of blood circulationGO:19035221100.014
regulation of kinase activityGO:00435491170.014
organophosphate catabolic processGO:00464341480.014
Worm
embryonic limb morphogenesisGO:003032640.014
single organism intracellular transportGO:19025821660.014
establishment of planar polarityGO:000173610.014
positive regulation of cellular amine metabolic processGO:003324030.014
nucleobase containing compound catabolic processGO:00346551520.014
Worm
regulation of proteasomal protein catabolic processGO:006113640.013
b cell differentiationGO:003018320.013
nucleoside phosphate catabolic processGO:19012921400.013
Worm
developmental process involved in reproductionGO:00030061590.013
carbohydrate derivative biosynthetic processGO:19011371240.013
response to hyperoxiaGO:0055093450.013
multicellular organism reproductionGO:00325042330.013
sensory perceptionGO:00076001010.013
positive regulation of protein modification processGO:00314011420.013
purine nucleotide catabolic processGO:00061951360.013
Worm
response to mechanical stimulusGO:00096121340.013
synaptic growth at neuromuscular junctionGO:005112410.013
organophosphate metabolic processGO:00196373700.013
Worm
positive regulation of secretionGO:00510471400.013
negative regulation of neurogenesisGO:0050768780.013
regulation of neuron deathGO:19012141150.013
purine ribonucleoside metabolic processGO:00461281680.013
Worm
cardiac ventricle developmentGO:000323110.013
response to toxic substanceGO:00096361330.013
response to vitaminGO:00332731310.013
cellular response to steroid hormone stimulusGO:0071383930.013
reproductive system developmentGO:00614581280.013
monocarboxylic acid metabolic processGO:00327871520.013
regulation of response to woundingGO:1903034690.013
negative regulation of signalingGO:00230571570.013
peptidyl amino acid modificationGO:00181931260.012
regulation of response to stressGO:00801341260.012
regulation of bmp signaling pathwayGO:003051020.012
regulation of programmed cell deathGO:00430673410.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
nucleotide catabolic processGO:00091661390.012
Worm
regulation of cell motilityGO:20001451310.012
positive regulation of cytosolic calcium ion concentrationGO:00072041220.012
muscle filament slidingGO:003004920.012
negative regulation of transcription dna templatedGO:00458921160.012
skeletal muscle cell differentiationGO:003591420.012
cell cycle checkpointGO:000007520.012
sequestering of metal ionGO:005123890.012
negative regulation of cellular component organizationGO:0051129830.012
multicellular organism growthGO:003526410.012
positive regulation of cellular component organizationGO:00511302000.012
ribonucleotide catabolic processGO:00092611360.012
Worm
ribonucleoside triphosphate metabolic processGO:00091991410.012
Worm
embryonic skeletal system developmentGO:004870630.012
striated muscle tissue developmentGO:0014706580.012
Mouse
epithelium developmentGO:0060429960.012
ras protein signal transductionGO:0007265290.012
regulation of cellular component movementGO:00512701500.012
purine containing compound catabolic processGO:00725231380.012
Worm
spermatogenesisGO:0007283990.012
regulation of transferase activityGO:00513381230.012
positive regulation of protein metabolic processGO:00512471780.012
response to increased oxygen levelsGO:0036296450.012
cell adhesionGO:00071551100.012
positive regulation of programmed cell deathGO:00430681570.012
cellular response to alcoholGO:0097306870.012
cellular response to cytokine stimulusGO:00713451270.012
regulation of muscle contractionGO:0006937530.012
gliogenesisGO:0042063930.012
metal ion transportGO:00300012890.012
glycosyl compound metabolic processGO:19016571820.012
Worm
negative regulation of cell developmentGO:0010721820.012
regulation of mapk cascadeGO:00434081160.012
organonitrogen compound biosynthetic processGO:19015661670.012
regulation of tube sizeGO:0035150890.011
response to biotic stimulusGO:00096072260.011
regulation of protein kinase activityGO:00458591050.011
gastrulationGO:000736920.011
rho protein signal transductionGO:0007266110.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
negative regulation of neuron differentiationGO:0045665620.011
cyclic nucleotide metabolic processGO:0009187800.011
positive regulation of mapk cascadeGO:0043410920.011
cellular response to abiotic stimulusGO:0071214850.011
cellular protein localizationGO:00346131220.011
male gamete generationGO:0048232990.011
regulation of growthGO:00400081050.011
positive regulation of intracellular signal transductionGO:19025331380.011
oxidation reduction processGO:00551143040.011
regulation of nucleotide metabolic processGO:00061401170.011
Worm
hepaticobiliary system developmentGO:0061008900.011
cellular response to fluid shear stressGO:007149840.011
tube developmentGO:0035295890.011
mapk cascadeGO:00001651400.011
negative regulation of rna biosynthetic processGO:19026791180.011
response to other organismGO:00517072200.011
negative regulation of neuron projection developmentGO:0010977460.011
nucleoside phosphate biosynthetic processGO:19012931020.011
cellular response to peptide hormone stimulusGO:00713751200.011
regulation of blood vessel sizeGO:0050880890.011
response to hexoseGO:00097461440.011
vasoconstrictionGO:0042310540.011
purine ribonucleotide biosynthetic processGO:0009152810.011
rhythmic processGO:00485111560.011
response to temperature stimulusGO:0009266940.011
negative regulation of mitotic cell cycle phase transitionGO:190199130.011
negative regulation of cell communicationGO:00106481580.011
muscle organ developmentGO:0007517500.011
hormone transportGO:00099141210.011
ribonucleoside metabolic processGO:00091191740.011
Worm
cytoskeleton dependent cytokinesisGO:006164020.011
neuronal action potentialGO:0019228350.011
cellular macromolecule localizationGO:00707271220.011
regulation of response to external stimulusGO:00321011060.011
mesoderm developmentGO:000749820.011
cytoplasmic transportGO:00164821150.011
carbohydrate biosynthetic processGO:0016051420.010
negative regulation of cell deathGO:00605482290.010
vascular process in circulatory systemGO:0003018960.010
regulation of cell migrationGO:00303341280.010
negative regulation of phosphorus metabolic processGO:0010563800.010
regulation of catabolic processGO:00098941130.010
Worm
g protein coupled receptor signaling pathwayGO:00071862420.010
atp metabolic processGO:0046034720.010
nucleoside monophosphate metabolic processGO:0009123930.010
positive regulation of cell projection organizationGO:00313461110.010
cytoskeleton organizationGO:00070101110.010
Worm
inflammatory responseGO:00069541500.010
positive regulation of neuron differentiationGO:00456661260.010
non canonical wnt signaling pathwayGO:003556730.010
regulation of notch signaling pathwayGO:000859330.010
purine ribonucleotide catabolic processGO:00091541360.010
Worm
regulation of cell morphogenesis involved in differentiationGO:0010769720.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
Worm
spindle organizationGO:000705120.010
regulation of alternative mrna splicing via spliceosomeGO:000038120.010
eye morphogenesisGO:004859240.010
negative regulation of canonical wnt signaling pathwayGO:009009040.010
response to alkaloidGO:00432791320.010
immune system processGO:00023762040.010
hexose metabolic processGO:0019318580.010
response to amino acidGO:0043200750.010

Speg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
Human
cardiovascular system diseaseDOID:128700.016
nervous system diseaseDOID:86300.013
gastrointestinal system diseaseDOID:7700.011
musculoskeletal system diseaseDOID:1700.010
Human
muscular diseaseDOID:008000000.010
Human
muscle tissue diseaseDOID:6600.010
Human