IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

C1qtnf2

C1q and tumor necrosis factor related protein 2

(Aliases: RGD1561041)

RGD: 1561041
Ensembl: ENSRNOG00000003870
Entrez: 497886
UniProtKB: D3ZCS2

Process Predictions
Disease Predictions

C1qtnf2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular component assembly	GO:0022607	360	0.103	Mouse
cellular component biogenesis	GO:0044085	368	0.081	Mouse
response to oxygen levels	GO:0070482	265	0.063
protein oligomerization	GO:0051259	191	0.046	Mouse
protein homooligomerization	GO:0051260	91	0.046	Mouse
response to decreased oxygen levels	GO:0036293	237	0.045
cellular ion homeostasis	GO:0006873	184	0.044
macromolecular complex subunit organization	GO:0043933	339	0.041	Mouse
regulation of phosphate metabolic process	GO:0019220	349	0.041	Mouse
protein complex biogenesis	GO:0070271	263	0.039	Mouse
nucleic acid templated transcription	GO:0097659	379	0.037
protein phosphorylation	GO:0006468	345	0.037	Mouse
cellular response to stress	GO:0033554	269	0.036
positive regulation of rna metabolic process	GO:0051254	203	0.035
wound healing	GO:0042060	122	0.035
protein complex assembly	GO:0006461	263	0.035	Mouse
regulation of phosphorylation	GO:0042325	248	0.031	Mouse
regeneration	GO:0031099	163	0.031
organophosphate metabolic process	GO:0019637	370	0.030
cellular amino acid metabolic process	GO:0006520	107	0.028
brain development	GO:0007420	247	0.027	Rat
macromolecular complex assembly	GO:0065003	273	0.027	Mouse
regulation of signal transduction	GO:0009966	318	0.027	Mouse
regulation of multicellular organismal development	GO:2000026	376	0.027
reproductive structure development	GO:0048608	128	0.027
nucleoside phosphate metabolic process	GO:0006753	283	0.026
cardiovascular system development	GO:0072358	134	0.024
cation homeostasis	GO:0055080	195	0.024
organic acid metabolic process	GO:0006082	292	0.023	Mouse
oxoacid metabolic process	GO:0043436	290	0.023	Mouse
cellular amine metabolic process	GO:0044106	38	0.022
regulation of rna metabolic process	GO:0051252	391	0.022
regulation of cellular amine metabolic process	GO:0033238	8	0.022
artery development	GO:0060840	3	0.022
metal ion homeostasis	GO:0055065	186	0.022
positive regulation of phosphate metabolic process	GO:0045937	262	0.022	Mouse
protein complex subunit organization	GO:0071822	302	0.021	Mouse
cellular metal ion homeostasis	GO:0006875	172	0.021
nucleotide metabolic process	GO:0009117	279	0.021
positive regulation of gene expression	GO:0010628	244	0.021
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.020
divalent inorganic cation homeostasis	GO:0072507	165	0.020
positive regulation of phosphorus metabolic process	GO:0010562	262	0.019	Mouse
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.019
regulation of rna biosynthetic process	GO:2001141	381	0.019
cellular cation homeostasis	GO:0030003	180	0.019
purine nucleotide metabolic process	GO:0006163	229	0.019
vasculature development	GO:0001944	70	0.019
limb morphogenesis	GO:0035108	4	0.018
cellular response to oxygen containing compound	GO:1901701	386	0.018
regulation of phosphorus metabolic process	GO:0051174	349	0.018	Mouse
carboxylic acid metabolic process	GO:0019752	289	0.018	Mouse
cellular homeostasis	GO:0019725	252	0.018
embryonic appendage morphogenesis	GO:0035113	4	0.017
establishment of tissue polarity	GO:0007164	2	0.017
response to extracellular stimulus	GO:0009991	380	0.017
transcription from rna polymerase ii promoter	GO:0006366	252	0.017
response to hypoxia	GO:0001666	231	0.017
urogenital system development	GO:0001655	78	0.017
epithelium development	GO:0060429	96	0.017
neuron development	GO:0048666	286	0.017
anatomical structure morphogenesis	GO:0009653	298	0.017
cellular response to hormone stimulus	GO:0032870	247	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017	Mouse
g protein coupled receptor signaling pathway	GO:0007186	242	0.017
multicellular organismal signaling	GO:0035637	44	0.017
regulation of nucleic acid templated transcription	GO:1903506	380	0.017
positive regulation of protein modification process	GO:0031401	142	0.017	Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.017
carbohydrate derivative metabolic process	GO:1901135	346	0.016
apoptotic process	GO:0006915	381	0.016
positive regulation of multicellular organismal process	GO:0051240	387	0.016
gastrulation	GO:0007369	2	0.016
regulation of nervous system development	GO:0051960	264	0.016
regulation of molecular function	GO:0065009	398	0.016	Mouse
positive regulation of rna biosynthetic process	GO:1902680	197	0.016
ras protein signal transduction	GO:0007265	29	0.016
regulation of transcription dna templated	GO:0006355	374	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.016
regulation of cellular amino acid metabolic process	GO:0006521	2	0.015
regulation of apoptotic process	GO:0042981	335	0.015
ion homeostasis	GO:0050801	212	0.015
positive regulation of signal transduction	GO:0009967	175	0.015	Mouse
appendage morphogenesis	GO:0035107	4	0.015
single organism reproductive process	GO:0044702	297	0.015
circulatory system development	GO:0072359	134	0.015
small gtpase mediated signal transduction	GO:0007264	36	0.015
carbohydrate derivative biosynthetic process	GO:1901137	124	0.015
multi organism reproductive process	GO:0044703	262	0.015
metal ion transport	GO:0030001	289	0.015
cellular response to nitrogen compound	GO:1901699	210	0.015
developmental process involved in reproduction	GO:0003006	159	0.015
rna metabolic process	GO:0016070	406	0.015
growth	GO:0040007	165	0.015
blood vessel development	GO:0001568	69	0.015
response to nutrient levels	GO:0031667	370	0.015
response to wounding	GO:0009611	254	0.015
regulation of establishment of planar polarity	GO:0090175	2	0.015
regulation of membrane potential	GO:0042391	110	0.015
tissue development	GO:0009888	252	0.015
sequestering of metal ion	GO:0051238	9	0.014
cardiac chamber development	GO:0003205	1	0.014
neuronal action potential	GO:0019228	35	0.014
amine metabolic process	GO:0009308	38	0.014
monovalent inorganic cation transport	GO:0015672	172	0.014
ribose phosphate metabolic process	GO:0019693	235	0.014
organic substance catabolic process	GO:1901575	316	0.014
cellular response to external stimulus	GO:0071496	118	0.014
cyclic nucleotide metabolic process	GO:0009187	80	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
positive regulation of molecular function	GO:0044093	230	0.014	Mouse
rhythmic process	GO:0048511	156	0.014
nucleobase containing small molecule metabolic process	GO:0055086	316	0.013
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.013
homeostatic process	GO:0042592	331	0.013
response to nutrient	GO:0007584	248	0.013
rna biosynthetic process	GO:0032774	380	0.013
regulation of kinase activity	GO:0043549	117	0.013	Mouse
cytosolic calcium ion homeostasis	GO:0051480	140	0.013
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.013
programmed cell death	GO:0012501	392	0.013
cellular calcium ion homeostasis	GO:0006874	160	0.013
cell projection organization	GO:0030030	302	0.013
gland development	GO:0048732	155	0.013
action potential	GO:0001508	54	0.013
collagen fibril organization	GO:0030199	1	0.013
cellular ketone metabolic process	GO:0042180	51	0.013	Mouse
regulation of cellular ketone metabolic process	GO:0010565	27	0.013	Mouse
neuron differentiation	GO:0030182	368	0.013
reproductive process	GO:0022414	372	0.013
cellular response to peptide	GO:1901653	133	0.013
positive regulation of intracellular signal transduction	GO:1902533	138	0.012	Mouse
regulation of purine nucleotide metabolic process	GO:1900542	115	0.012
transmembrane transport	GO:0055085	412	0.012
chemical homeostasis	GO:0048878	292	0.012
female pregnancy	GO:0007565	122	0.012
positive regulation of phosphorylation	GO:0042327	177	0.012	Mouse
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.012	Mouse
positive regulation of developmental process	GO:0051094	283	0.012
cellular response to endogenous stimulus	GO:0071495	377	0.012
response to peptide hormone	GO:0043434	278	0.012
carbohydrate metabolic process	GO:0005975	130	0.012	Mouse
cell type specific apoptotic process	GO:0097285	134	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
positive regulation of nervous system development	GO:0051962	178	0.012
response to inorganic substance	GO:0010035	377	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012
regulation of protein phosphorylation	GO:0001932	183	0.012	Mouse
response to mechanical stimulus	GO:0009612	134	0.011
calcium ion homeostasis	GO:0055074	162	0.011
positive regulation of biosynthetic process	GO:0009891	319	0.011	Mouse
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
negative regulation of cardiac muscle tissue development	GO:0055026	3	0.011
regulation of neurogenesis	GO:0050767	247	0.011
maternal process involved in female pregnancy	GO:0060135	38	0.011
central nervous system development	GO:0007417	311	0.011	Rat
positive regulation of transcription dna templated	GO:0045893	197	0.011
cellular catabolic process	GO:0044248	295	0.011
maintenance of location	GO:0051235	17	0.011
multi multicellular organism process	GO:0044706	138	0.011
regulation of blood circulation	GO:1903522	110	0.011
response to vitamin	GO:0033273	131	0.011
rho protein signal transduction	GO:0007266	11	0.011
ribonucleotide metabolic process	GO:0009259	231	0.011
retinoic acid receptor signaling pathway	GO:0048384	7	0.011
positive regulation of apoptotic process	GO:0043065	154	0.011
catabolic process	GO:0009056	351	0.011
receptor mediated endocytosis	GO:0006898	42	0.011
regulation of cell proliferation	GO:0042127	359	0.011
head development	GO:0060322	247	0.011	Rat
regulation of response to stress	GO:0080134	126	0.011
regulation of programmed cell death	GO:0043067	341	0.011
response to monosaccharide	GO:0034284	159	0.011
negative regulation of macromolecule metabolic process	GO:0010605	260	0.011
cytoplasmic transport	GO:0016482	115	0.011
embryonic limb morphogenesis	GO:0030326	4	0.011
response to glucocorticoid	GO:0051384	223	0.011	Rat
regulation of system process	GO:0044057	208	0.010
regulation of cellular component organization	GO:0051128	368	0.010
response to carbohydrate	GO:0009743	183	0.010
negative regulation of gene expression	GO:0010629	199	0.010
sex differentiation	GO:0007548	113	0.010
response to estrogen	GO:0043627	232	0.010
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.010

C1qtnf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
musculoskeletal system disease	DOID:17	0.029
disease of anatomical entity	DOID:7	0.029
muscular disease	DOID:0080000	0.019
muscular dystrophy	DOID:9884	0.019
muscle tissue disease	DOID:66	0.019
myopathy	DOID:423	0.019
nervous system disease	DOID:863	0.017

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