Rattus norvegicus

7 known processes

Ppm1e

protein phosphatase 1E (PP2C domain containing)

Ppm1e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to inorganic substanceGO:00100353770.056
carboxylic acid metabolic processGO:00197522890.049
apoptotic processGO:00069153810.045
Rat
organic acid metabolic processGO:00060822920.043
programmed cell deathGO:00125013920.043
Rat
cation transportGO:00068123820.043
organelle organizationGO:00069962660.042
Human Rat
transmembrane transportGO:00550854120.041
central nervous system developmentGO:00074173110.041
oxoacid metabolic processGO:00434362900.041
rna metabolic processGO:00160704060.040
macromolecular complex subunit organizationGO:00439333390.040
Human Rat
protein phosphorylationGO:00064683450.039
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.039
neuron projection developmentGO:00311752730.037
negative regulation of cellular metabolic processGO:00313242810.036
Human
cellular response to oxygen containing compoundGO:19017013860.036
carbohydrate derivative metabolic processGO:19011353460.035
response to estrogenGO:00436272320.034
response to metal ionGO:00100382530.033
negative regulation of nitrogen compound metabolic processGO:00511721610.033
negative regulation of metabolic processGO:00098923310.033
Human
intracellular signal transductionGO:00355563140.033
regulation of rna biosynthetic processGO:20011413810.032
cell projection organizationGO:00300303020.032
amine metabolic processGO:0009308380.032
cellular response to stressGO:00335542690.031
brain developmentGO:00074202470.031
positive regulation of phosphorus metabolic processGO:00105622620.030
regulation of rna metabolic processGO:00512523910.030
neuron developmentGO:00486662860.030
positive regulation of transportGO:00510502450.030
negative regulation of biosynthetic processGO:00098901680.029
cellular component assemblyGO:00226073600.029
Human
cellular amine metabolic processGO:0044106380.029
rna biosynthetic processGO:00327743800.029
ion transmembrane transportGO:00342203650.029
organophosphate metabolic processGO:00196373700.029
negative regulation of macromolecule metabolic processGO:00106052600.028
Human
cellular amino acid metabolic processGO:00065201070.028
regulation of cellular amino acid metabolic processGO:000652120.028
head developmentGO:00603222470.028
positive regulation of biosynthetic processGO:00098913190.028
response to peptideGO:19016522920.028
macromolecular complex assemblyGO:00650032730.028
response to nutrient levelsGO:00316673700.028
regulation of molecular functionGO:00650093980.028
Human Rat
single organism biosynthetic processGO:00447113420.027
secretionGO:00469033070.027
response to extracellular stimulusGO:00099913800.027
anatomical structure morphogenesisGO:00096532980.027
transcription dna templatedGO:00063513770.027
regulation of phosphorus metabolic processGO:00511743490.027
Human
protein complex assemblyGO:00064612630.027
cell cell signalingGO:00072673350.027
synaptic transmissionGO:00072682350.026
nucleoside phosphate metabolic processGO:00067532830.026
positive regulation of molecular functionGO:00440932300.026
Rat
regulation of protein metabolic processGO:00512462890.026
Human Rat
regulation of cellular amine metabolic processGO:003323880.026
cellular response to hormone stimulusGO:00328702470.026
nucleic acid templated transcriptionGO:00976593790.025
cellular chemical homeostasisGO:00550822470.025
protein complex biogenesisGO:00702712630.025
cellular component biogenesisGO:00440853680.025
Human
metal ion transportGO:00300012890.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
regulation of cell proliferationGO:00421273590.025
regulation of transcription dna templatedGO:00063553740.025
protein complex subunit organizationGO:00718223020.025
Human
regulation of neurogenesisGO:00507672470.025
neuron differentiationGO:00301823680.025
regulation of cellular ketone metabolic processGO:0010565270.025
negative regulation of cellular biosynthetic processGO:00313271610.025
secretion by cellGO:00329402480.025
response to corticosteroidGO:00319602350.025
regulation of multicellular organismal developmentGO:20000263760.024
negative regulation of gene expressionGO:00106291990.024
positive regulation of phosphate metabolic processGO:00459372620.024
regulation of apoptotic processGO:00429813350.024
Rat
response to cytokineGO:00340972150.024
response to carbohydrateGO:00097431830.024
nitrogen compound transportGO:00717052290.024
cellular response to endogenous stimulusGO:00714953770.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
nucleobase containing small molecule metabolic processGO:00550863160.024
cation homeostasisGO:00550801950.024
lipid metabolic processGO:00066292830.023
nucleotide metabolic processGO:00091172790.023
positive regulation of multicellular organismal processGO:00512403870.023
purine containing compound metabolic processGO:00725212530.023
response to oxygen levelsGO:00704822650.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
response to acid chemicalGO:00011012220.023
cellular response to nitrogen compoundGO:19016992100.022
calcium ion homeostasisGO:00550741620.022
ribose phosphate metabolic processGO:00196932350.022
cellular metal ion homeostasisGO:00068751720.022
cellular cation homeostasisGO:00300031800.022
regulation of neuron differentiationGO:00456642080.022
regulation of cellular localizationGO:00603412630.022
catabolic processGO:00090563510.022
cation transmembrane transportGO:00986552630.022
regulation of ion transportGO:00432692450.022
metal ion homeostasisGO:00550651860.022
divalent inorganic cation homeostasisGO:00725071650.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
positive regulation of cell proliferationGO:00082842490.021
protein oligomerizationGO:00512591910.021
regulation of catalytic activityGO:00507903040.021
Human Rat
regulation of nervous system developmentGO:00519602640.021
regulation of cell differentiationGO:00455953200.021
chemical homeostasisGO:00488782920.021
regulation of phosphate metabolic processGO:00192203490.021
Human
regulation of cell developmentGO:00602842630.021
positive regulation of macromolecule biosynthetic processGO:00105572470.021
carbohydrate derivative biosynthetic processGO:19011371240.021
positive regulation of developmental processGO:00510942830.020
response to decreased oxygen levelsGO:00362932370.020
cellular ketone metabolic processGO:0042180510.020
multicellular organismal reproductive processGO:00486092330.020
homeostatic processGO:00425923310.020
regulation of secretion by cellGO:19035302080.020
positive regulation of response to stimulusGO:00485842850.020
cellular calcium ion homeostasisGO:00068741600.020
regulation of programmed cell deathGO:00430673410.020
Rat
transcription from rna polymerase ii promoterGO:00063662520.020
positive regulation of cellular amine metabolic processGO:003324030.020
positive regulation of cellular biosynthetic processGO:00313282950.020
purine ribonucleotide metabolic processGO:00091502270.020
response to ketoneGO:19016541820.020
ion homeostasisGO:00508012120.020
positive regulation of gene expressionGO:00106282440.020
response to glucocorticoidGO:00513842230.020
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
single organism catabolic processGO:00447122830.020
regulation of phosphorylationGO:00423252480.019
Human
cellular homeostasisGO:00197252520.019
g protein coupled receptor signaling pathwayGO:00071862420.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
cytosolic calcium ion homeostasisGO:00514801400.019
regulation of cellular protein metabolic processGO:00322682670.019
Human Rat
intracellular transportGO:00469071850.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
regulation of signal transductionGO:00099663180.019
negative regulation of cell deathGO:00605482290.019
positive regulation of transcription dna templatedGO:00458931970.019
growthGO:00400071650.019
cellular ion homeostasisGO:00068731840.018
response to oxidative stressGO:00069791860.018
regulation of secretionGO:00510462240.018
cellular response to lipidGO:00713962010.018
single organism reproductive processGO:00447022970.018
purine nucleotide metabolic processGO:00061632290.018
response to hexoseGO:00097461440.018
positive regulation of cell differentiationGO:00455972170.018
reproductive processGO:00224143720.018
regulation of cell projection organizationGO:00313441750.018
cell morphogenesisGO:00009021420.018
positive regulation of secretion by cellGO:19035321280.018
cell cycle checkpointGO:000007520.018
response to growth factorGO:00708481890.018
positive regulation of phosphorylationGO:00423271770.018
regulation of hormone levelsGO:00108171870.018
cellular response to peptideGO:19016531330.018
cellular component morphogenesisGO:00329891550.018
organic substance catabolic processGO:19015753160.018
anion transportGO:00068201780.018
positive regulation of catalytic activityGO:00430851840.017
Rat
gland developmentGO:00487321550.017
regulation of synaptic transmissionGO:00508041410.017
locomotionGO:00400112370.017
positive regulation of cellular component organizationGO:00511302000.017
Human
response to woundingGO:00096112540.017
cellular response to cytokine stimulusGO:00713451270.017
cellular component movementGO:00069282480.017
inorganic ion transmembrane transportGO:00986602290.017
dna metabolic processGO:0006259960.017
response to peptide hormoneGO:00434342780.017
agingGO:00075682410.017
positive regulation of rna metabolic processGO:00512542030.017
cellular response to growth factor stimulusGO:00713631620.017
cell projection morphogenesisGO:00488581230.017
signal releaseGO:00230611450.017
single organism intracellular transportGO:19025821660.017
response to transition metal nanoparticleGO:19902671220.017
neurological system processGO:00508772190.017
response to monosaccharideGO:00342841590.017
cell type specific apoptotic processGO:00972851340.017
cellular lipid metabolic processGO:00442552080.017
monovalent inorganic cation transportGO:00156721720.017
response to bacteriumGO:00096172000.017
positive regulation of neurogenesisGO:00507691650.017
regenerationGO:00310991630.017
positive regulation of protein metabolic processGO:00512471780.016
Rat
response to other organismGO:00517072200.016
behaviorGO:00076102050.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
divalent metal ion transportGO:00708381320.016
macromolecule localizationGO:00330362520.016
positive regulation of nervous system developmentGO:00519621780.016
purine ribonucleoside metabolic processGO:00461281680.016
circulatory system processGO:00030131830.016
response to hypoxiaGO:00016662310.016
positive regulation of cell communicationGO:00106472710.016
ribonucleotide metabolic processGO:00092592310.016
response to nutrientGO:00075842480.016
regulation of cellular component organizationGO:00511283680.016
Human
positive regulation of apoptotic processGO:00430651540.016
Rat
regulation of intracellular signal transductionGO:19025312180.016
regulation of neuron projection developmentGO:00109751610.016
lipid biosynthetic processGO:00086101280.016
negative regulation of rna metabolic processGO:00512531230.016
multicellular organism reproductionGO:00325042330.016
regulation of hydrolase activityGO:00513361430.016
Rat
glycosyl compound metabolic processGO:19016571820.016
establishment of protein localizationGO:00451841410.016
reproductionGO:00000032450.016
calcium ion transportGO:00068161310.016
nucleoside metabolic processGO:00091161790.016
heart morphogenesisGO:000300730.016
heterocycle catabolic processGO:00467001670.015
positive regulation of neuron differentiationGO:00456661260.015
negative regulation of programmed cell deathGO:00430691830.015
response to estradiolGO:00323551640.015
negative regulation of cell communicationGO:00106481580.015
response to lipopolysaccharideGO:00324961910.015
positive regulation of secretionGO:00510471400.015
positive regulation of signalingGO:00230562700.015
positive regulation of cell developmentGO:00107201760.015
peptidyl amino acid modificationGO:00181931260.015
response to radiationGO:00093141370.015
negative regulation of rna biosynthetic processGO:19026791180.015
cellular response to organic cyclic compoundGO:00714072020.015
regulation of protein modification processGO:00313991940.015
Human
positive regulation of rna biosynthetic processGO:19026801970.015
nucleotide biosynthetic processGO:0009165980.015
circulatory system developmentGO:00723591340.015
response to molecule of bacterial originGO:00022371940.015
multi organism reproductive processGO:00447032620.015
dna integrity checkpointGO:003157020.015
blood circulationGO:00080151830.015
anterior posterior pattern specificationGO:000995210.015
divalent inorganic cation transportGO:00725111340.015
inorganic cation transmembrane transportGO:00986622020.014
response to glucoseGO:00097491360.014
purine nucleotide biosynthetic processGO:0006164830.014
negative regulation of apoptotic processGO:00430661810.014
organic cyclic compound catabolic processGO:19013611750.014
response to external biotic stimulusGO:00432072210.014
response to campGO:0051591910.014
single organism organelle organizationGO:19025891800.014
Human Rat
positive regulation of intracellular signal transductionGO:19025331380.014
cellular response to peptide hormone stimulusGO:00713751200.014
cytoskeleton organizationGO:00070101110.014
Human
muscle system processGO:00030121150.014
cellular catabolic processGO:00442482950.014
response to purine containing compoundGO:00140741260.014
protein transportGO:00150311320.014
rhythmic processGO:00485111560.014
negative regulation of multicellular organismal processGO:00512412030.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
negative regulation of transcription dna templatedGO:00458921160.014
cell morphogenesis involved in differentiationGO:00009041190.014
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
positive regulation of cell deathGO:00109421840.014
Rat
nucleobase containing compound catabolic processGO:00346551520.014
response to biotic stimulusGO:00096072260.014
negative regulation of cell cycle phase transitionGO:190198840.014
purine containing compound biosynthetic processGO:0072522850.014
protein localizationGO:00081041910.014
regulation of membrane potentialGO:00423911100.013
organophosphate biosynthetic processGO:00904071430.013
cellular response to organonitrogen compoundGO:00714171970.013
regulation of anatomical structure sizeGO:00900661350.013
cell migrationGO:00164771970.013
small molecule biosynthetic processGO:00442831240.013
axis specificationGO:000979840.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
cell motilityGO:00488702020.013
cellular nitrogen compound catabolic processGO:00442701630.013
negative regulation of transportGO:00510511360.013
cell cycleGO:00070491010.013
response to insulinGO:00328681330.013
cell morphogenesis involved in neuron differentiationGO:00486671060.013
developmental process involved in reproductionGO:00030061590.013
small gtpase mediated signal transductionGO:0007264360.013
defense responseGO:00069521940.013
single organism behaviorGO:00447081300.013
regulation of nucleotide metabolic processGO:00061401170.013
vesicle mediated transportGO:00161921810.013
positive regulation of neuron projection developmentGO:0010976990.013
eye morphogenesisGO:004859240.013
regulation of metal ion transportGO:00109591180.013
localization of cellGO:00516742020.013
cell part morphogenesisGO:00329901230.013
regulation of system processGO:00440572080.013
neuron deathGO:00709971270.012
hormone secretionGO:00468791150.012
negative regulation of signalingGO:00230571570.012
ras protein signal transductionGO:0007265290.012
neuron projection morphogenesisGO:00488121220.012
response to ethanolGO:00454711620.012
signal transduction by phosphorylationGO:00230141440.012
regulation of organelle organizationGO:0033043800.012
Human
aromatic compound catabolic processGO:00194391680.012
cellular response to abiotic stimulusGO:0071214850.012
hormone transportGO:00099141210.012
positive regulation of programmed cell deathGO:00430681570.012
Rat
limb morphogenesisGO:003510840.012
organonitrogen compound catabolic processGO:19015651790.012
ribose phosphate biosynthetic processGO:0046390870.012
positive regulation of protein modification processGO:00314011420.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
positive regulation of cellular protein metabolic processGO:00322701670.012
Rat
gastrulationGO:000736920.012
developmental growthGO:00485891000.012
carbohydrate derivative catabolic processGO:19011361470.012
ribonucleoside metabolic processGO:00091191740.012
regulation of protein phosphorylationGO:00019321830.012
Human
response to toxic substanceGO:00096361330.012
tissue developmentGO:00098882520.012
forebrain developmentGO:0030900980.012
liver developmentGO:0001889900.012
proteolysisGO:00065081750.012
Rat
response to organophosphorusGO:00466831020.012
response to amino acidGO:0043200750.012
purine nucleoside metabolic processGO:00422781690.012
organ regenerationGO:00311001010.012
cytoplasmic transportGO:00164821150.012
response to mechanical stimulusGO:00096121340.012
single organism carbohydrate metabolic processGO:00447231180.012
regulation of mapk cascadeGO:00434081160.012
regulation of cellular component movementGO:00512701500.012
response to temperature stimulusGO:0009266940.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
positive regulation of signal transductionGO:00099671750.012
purine ribonucleoside triphosphate metabolic processGO:00092051400.012
maintenance of locationGO:0051235170.011
regulation of homeostatic processGO:00328441010.011
regulation of locomotionGO:00400121480.011
regulation of cell cycleGO:0051726730.011
response to alkaloidGO:00432791320.011
regulation of purine nucleotide metabolic processGO:19005421150.011
multicellular organism growthGO:003526410.011
nucleoside phosphate biosynthetic processGO:19012931020.011
protein homooligomerizationGO:0051260910.011
negative regulation of response to stimulusGO:00485851550.011
organonitrogen compound biosynthetic processGO:19015661670.011
cellular response to external stimulusGO:00714961180.011
cyclic nucleotide metabolic processGO:0009187800.011
embryonic appendage morphogenesisGO:003511340.011
peptide transportGO:0015833970.011
sequestering of calcium ionGO:005120880.011
response to vitaminGO:00332731310.011
regulation of hormone secretionGO:00468831060.011
spermatogenesisGO:0007283990.011
purine nucleotide catabolic processGO:00061951360.011
regulation of transmembrane transportGO:00347621220.011
sex differentiationGO:00075481130.011
amide transportGO:00428861050.011
axon developmentGO:0061564960.011
positive regulation of cell projection organizationGO:00313461110.011
positive regulation of nucleotide metabolic processGO:0045981910.011
negative regulation of catalytic activityGO:00430861030.011
Human
sequestering of metal ionGO:005123890.011
gamete generationGO:00072761240.011
carbohydrate metabolic processGO:00059751300.011
positive regulation of ion transportGO:0043270940.011
regulation of ion transmembrane transportGO:00347651210.011
meiotic cell cycle processGO:190304630.011
cytokine biosynthetic processGO:004208930.011
organic anion transportGO:00157111320.011
regulation of dna metabolic processGO:0051052600.011
organic hydroxy compound metabolic processGO:19016151150.011
hepaticobiliary system developmentGO:0061008900.011
positive regulation of protein phosphorylationGO:00019341350.011
cellular response to insulin stimulusGO:0032869810.011
negative regulation of innate immune responseGO:004582440.010
regulation of response to stressGO:00801341260.010
immune system processGO:00023762040.010
male gamete generationGO:0048232990.010
regulation of transferase activityGO:00513381230.010
Human
synaptic growth at neuromuscular junctionGO:005112410.010
nucleotide catabolic processGO:00091661390.010
rho protein signal transductionGO:0007266110.010
monocarboxylic acid metabolic processGO:00327871520.010
protein heterooligomerizationGO:0051291890.010
neuron apoptotic processGO:0051402880.010
sexual reproductionGO:00199531480.010
embryonic pattern specificationGO:000988010.010
positive regulation of mapk cascadeGO:0043410920.010
potassium ion transportGO:0006813970.010
circadian rhythmGO:0007623880.010
dephosphorylationGO:0016311980.010
salivary gland developmentGO:000743130.010
development of primary sexual characteristicsGO:00451371070.010
organic acid transportGO:00158491160.010
negative regulation of phosphate metabolic processGO:0045936800.010
Human
oxidation reduction processGO:00551143040.010
protein autophosphorylationGO:0046777660.010
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
regulation of response to external stimulusGO:00321011060.010

Ppm1e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.026
disease of anatomical entityDOID:700.026
musculoskeletal system diseaseDOID:1700.015
sensory system diseaseDOID:005015500.015
disease of metabolismDOID:001466700.014
central nervous system diseaseDOID:33100.012
eye and adnexa diseaseDOID:149200.010