Rattus norvegicus

113 known processes

Vhl

von Hippel-Lindau tumor suppressor

(Aliases: Vhlh)

Vhl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to oxidative stressGO:00069791860.112
cellular response to oxygen containing compoundGO:19017013860.106
response to oxygen levelsGO:00704822650.104
cation transportGO:00068123820.094
nitrogen compound transportGO:00717052290.089
response to toxic substanceGO:00096361330.088
cellular response to peptide hormone stimulusGO:00713751200.081
apoptotic processGO:00069153810.076
negative regulation of cellular metabolic processGO:00313242810.076
negative regulation of signalingGO:00230571570.074
response to hypoxiaGO:00016662310.072
positive regulation of nitrogen compound metabolic processGO:00511733340.070
cation transmembrane transportGO:00986552630.068
negative regulation of macromolecule metabolic processGO:00106052600.067
response to insulinGO:00328681330.066
response to inorganic substanceGO:00100353770.066
regulation of nucleic acid templated transcriptionGO:19035063800.066
transcription dna templatedGO:00063513770.064
regulation of apoptotic processGO:00429813350.060
organic acid metabolic processGO:00060822920.059
rna biosynthetic processGO:00327743800.059
regulation of multicellular organismal developmentGO:20000263760.059
response to peptide hormoneGO:00434342780.059
response to hexoseGO:00097461440.059
reproductive processGO:00224143720.058
regulation of intracellular signal transductionGO:19025312180.058
blood circulationGO:00080151830.058
response to fungicideGO:0060992200.056
intracellular signal transductionGO:00355563140.056
response to radiationGO:00093141370.055
response to peptideGO:19016522920.055
response to decreased oxygen levelsGO:00362932370.055
cellular response to stressGO:00335542690.055
ion transmembrane transportGO:00342203650.054
regulation of catalytic activityGO:00507903040.053
central nervous system developmentGO:00074173110.053
metal ion transportGO:00300012890.052
monovalent inorganic cation transportGO:00156721720.052
cellular response to insulin stimulusGO:0032869810.052
positive regulation of transportGO:00510502450.052
inorganic ion transmembrane transportGO:00986602290.052
cellular response to organonitrogen compoundGO:00714171970.052
regulation of transcription dna templatedGO:00063553740.051
neurological system processGO:00508772190.051
regulation of blood vessel sizeGO:0050880890.050
response to carbohydrateGO:00097431830.049
transmembrane transportGO:00550854120.049
programmed cell deathGO:00125013920.048
cellular response to nitrogen compoundGO:19016992100.048
cellular response to organic cyclic compoundGO:00714072020.048
cellular response to endogenous stimulusGO:00714953770.047
rna metabolic processGO:00160704060.047
cellular component assemblyGO:00226073600.046
negative regulation of metabolic processGO:00098923310.046
cardiovascular system developmentGO:00723581340.046
tissue developmentGO:00098882520.046
response to corticosteroidGO:00319602350.045
regulation of system processGO:00440572080.045
regulation of rna biosynthetic processGO:20011413810.045
regulation of secretionGO:00510462240.045
negative regulation of response to stimulusGO:00485851550.045
intracellular transportGO:00469071850.045
vesicle mediated transportGO:00161921810.044
cellular catabolic processGO:00442482950.044
cellular chemical homeostasisGO:00550822470.044
response to acid chemicalGO:00011012220.044
response to glucoseGO:00097491360.043
organic substance catabolic processGO:19015753160.043
macromolecular complex assemblyGO:00650032730.043
negative regulation of programmed cell deathGO:00430691830.043
ras protein signal transductionGO:0007265290.043
regulation of cellular localizationGO:00603412630.043
response to glucocorticoidGO:00513842230.042
regulation of molecular functionGO:00650093980.042
positive regulation of response to stimulusGO:00485842850.041
carboxylic acid metabolic processGO:00197522890.041
hormone transportGO:00099141210.041
positive regulation of biosynthetic processGO:00098913190.041
epithelium developmentGO:0060429960.041
regulation of hormone levelsGO:00108171870.041
cellular component biogenesisGO:00440853680.041
regulation of nervous system developmentGO:00519602640.041
regulation of phosphate metabolic processGO:00192203490.040
multi organism reproductive processGO:00447032620.040
positive regulation of macromolecule biosynthetic processGO:00105572470.040
negative regulation of nitrogen compound metabolic processGO:00511721610.040
regulation of secretion by cellGO:19035302080.039
cellular response to hormone stimulusGO:00328702470.039
regulation of rna metabolic processGO:00512523910.039
negative regulation of apoptotic processGO:00430661810.039
positive regulation of cell proliferationGO:00082842490.039
regulation of programmed cell deathGO:00430673410.038
positive regulation of multicellular organismal processGO:00512403870.038
anatomical structure morphogenesisGO:00096532980.038
chemical homeostasisGO:00488782920.038
negative regulation of multicellular organismal processGO:00512412030.037
positive regulation of phosphorylationGO:00423271770.037
protein localizationGO:00081041910.037
cell growthGO:00160491040.037
cellular response to peptideGO:19016531330.037
response to purine containing compoundGO:00140741260.037
circulatory system processGO:00030131830.036
catabolic processGO:00090563510.036
regulation of cell proliferationGO:00421273590.036
response to metal ionGO:00100382530.035
cardiac ventricle developmentGO:000323110.035
positive regulation of cell migrationGO:0030335960.035
organophosphate metabolic processGO:00196373700.035
negative regulation of cell deathGO:00605482290.035
oxoacid metabolic processGO:00434362900.035
neuron apoptotic processGO:0051402880.034
protein heterooligomerizationGO:0051291890.034
negative regulation of nucleic acid templated transcriptionGO:19035071170.034
negative regulation of biosynthetic processGO:00098901680.034
response to cytokineGO:00340972150.034
amide transportGO:00428861050.034
anion transportGO:00068201780.034
cellular cation homeostasisGO:00300031800.034
small gtpase mediated signal transductionGO:0007264360.034
positive regulation of phosphate metabolic processGO:00459372620.034
circulatory system developmentGO:00723591340.033
secretionGO:00469033070.033
multicellular organism reproductionGO:00325042330.033
homeostatic processGO:00425923310.033
neural crest cell differentiationGO:001403320.033
macromolecule localizationGO:00330362520.033
lipid metabolic processGO:00066292830.033
single organism intracellular transportGO:19025821660.033
positive regulation of signalingGO:00230562700.033
multicellular organismal reproductive processGO:00486092330.033
positive regulation of secretion by cellGO:19035321280.032
organonitrogen compound biosynthetic processGO:19015661670.032
neural crest cell developmentGO:001403220.032
regulation of neurogenesisGO:00507672470.032
inflammatory responseGO:00069541500.032
response to nutrient levelsGO:00316673700.031
response to reactive oxygen speciesGO:00003021200.031
negative regulation of nucleobase containing compound metabolic processGO:00459341530.031
ion homeostasisGO:00508012120.031
neuron deathGO:00709971270.031
regulation of peptide transportGO:0090087870.031
positive regulation of cellular biosynthetic processGO:00313282950.031
brain developmentGO:00074202470.031
organic hydroxy compound metabolic processGO:19016151150.031
negative regulation of rna biosynthetic processGO:19026791180.030
response to woundingGO:00096112540.030
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
regulation of cell developmentGO:00602842630.030
cognitionGO:0050890920.030
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
negative regulation of cell communicationGO:00106481580.030
epithelial cell differentiationGO:0030855710.030
agingGO:00075682410.030
cellular lipid metabolic processGO:00442552080.030
regulation of signal transductionGO:00099663180.030
negative regulation of gene expressionGO:00106291990.030
negative regulation of transcription dna templatedGO:00458921160.030
positive regulation of cell communicationGO:00106472710.030
cell cell signalingGO:00072673350.030
positive regulation of cell deathGO:00109421840.030
inorganic cation transmembrane transportGO:00986622020.029
hormone secretionGO:00468791150.029
blood vessel developmentGO:0001568690.029
sexual reproductionGO:00199531480.029
response to extracellular stimulusGO:00099913800.029
regulation of cellular component organizationGO:00511283680.029
cation homeostasisGO:00550801950.029
learning or memoryGO:0007611900.029
signal releaseGO:00230611450.029
cellular ion homeostasisGO:00068731840.029
cellular component movementGO:00069282480.029
carbohydrate derivative metabolic processGO:19011353460.029
transcription from rna polymerase ii promoterGO:00063662520.028
positive regulation of developmental processGO:00510942830.028
protein complex biogenesisGO:00702712630.028
regulation of peptide hormone secretionGO:0090276800.028
regulation of protein metabolic processGO:00512462890.027
peptide secretionGO:0002790860.027
cellular homeostasisGO:00197252520.027
nucleic acid templated transcriptionGO:00976593790.027
cell projection organizationGO:00300303020.027
regulation of phosphorylationGO:00423252480.027
secretion by cellGO:00329402480.027
response to monosaccharideGO:00342841590.027
positive regulation of programmed cell deathGO:00430681570.026
cellular response to lipidGO:00713962010.026
regulation of ion transportGO:00432692450.026
negative regulation of cellular biosynthetic processGO:00313271610.026
positive regulation of apoptotic processGO:00430651540.026
cell morphogenesisGO:00009021420.026
response to growth factorGO:00708481890.026
response to estrogenGO:00436272320.026
localization of cellGO:00516742020.026
regulation of tube sizeGO:0035150890.026
positive regulation of rna biosynthetic processGO:19026801970.026
regulation of cell migrationGO:00303341280.026
regulation of cell motilityGO:20001451310.025
positive regulation of transcription dna templatedGO:00458931970.025
behaviorGO:00076102050.025
regulation of cell growthGO:0001558850.025
cell type specific apoptotic processGO:00972851340.025
cellular amino acid metabolic processGO:00065201070.025
developmental process involved in reproductionGO:00030061590.025
positive regulation of signal transductionGO:00099671750.025
heart morphogenesisGO:000300730.025
cellular response to oxidative stressGO:0034599760.025
positive regulation of phosphorus metabolic processGO:00105622620.025
neuron developmentGO:00486662860.025
positive regulation of secretionGO:00510471400.024
protein phosphorylationGO:00064683450.024
peptide transportGO:0015833970.024
positive regulation of peptide secretionGO:0002793520.024
negative regulation of transportGO:00510511360.024
macromolecular complex subunit organizationGO:00439333390.024
positive regulation of rna metabolic processGO:00512542030.024
cellular amine metabolic processGO:0044106380.024
positive regulation of nucleic acid templated transcriptionGO:19035081970.024
regulation of cellular protein metabolic processGO:00322682670.024
regulation of blood circulationGO:19035221100.024
growthGO:00400071650.024
proteolysisGO:00065081750.023
anion transmembrane transportGO:0098656770.023
vasoconstrictionGO:0042310540.023
neuron differentiationGO:00301823680.023
amine metabolic processGO:0009308380.023
cellular response to cytokine stimulusGO:00713451270.023
regulation of neuron deathGO:19012141150.023
glucose homeostasisGO:0042593750.023
positive regulation of cell motilityGO:2000147970.023
response to biotic stimulusGO:00096072260.023
regulation of cell differentiationGO:00455953200.023
positive regulation of hormone secretionGO:0046887650.023
negative regulation of cell proliferationGO:00082851190.023
single organism behaviorGO:00447081300.023
angiogenesisGO:0001525530.023
regulation of hormone secretionGO:00468831060.023
defense responseGO:00069521940.022
neuron projection developmentGO:00311752730.022
response to alkaloidGO:00432791320.022
protein complex assemblyGO:00064612630.022
response to hydrogen peroxideGO:0042542890.022
regulation of hydrolase activityGO:00513361430.022
gamete generationGO:00072761240.022
single organism reproductive processGO:00447022970.021
cellular metal ion homeostasisGO:00068751720.021
peptide hormone secretionGO:0030072840.021
cellular response to external stimulusGO:00714961180.021
cellular response to growth factor stimulusGO:00713631620.021
regulation of membrane potentialGO:00423911100.021
negative regulation of developmental processGO:00510931250.021
regulation of cellular catabolic processGO:00313291010.021
positive regulation of peptide hormone secretionGO:0090277500.021
carbohydrate homeostasisGO:0033500750.021
gland developmentGO:00487321550.021
morphogenesis of embryonic epitheliumGO:001633130.021
nucleobase containing small molecule metabolic processGO:00550863160.021
regulation of metal ion transportGO:00109591180.021
single organism biosynthetic processGO:00447113420.021
negative regulation of neuron deathGO:1901215690.021
reproductionGO:00000032450.021
synaptic transmissionGO:00072682350.020
single organism catabolic processGO:00447122830.020
regulation of protein modification processGO:00313991940.020
cellular response to metal ionGO:0071248550.020
head developmentGO:00603222470.020
neural crest cell migrationGO:000175510.020
multi multicellular organism processGO:00447061380.020
protein oligomerizationGO:00512591910.020
response to lipopolysaccharideGO:00324961910.020
regulation of cellular amino acid metabolic processGO:000652120.020
action potentialGO:0001508540.020
positive regulation of gene expressionGO:00106282440.020
divalent metal ion transportGO:00708381320.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
cell migrationGO:00164771970.019
response to molecule of bacterial originGO:00022371940.019
regenerationGO:00310991630.019
positive regulation of molecular functionGO:00440932300.019
metal ion homeostasisGO:00550651860.019
positive regulation of catalytic activityGO:00430851840.019
axon cargo transportGO:000808810.019
positive regulation of cell differentiationGO:00455972170.019
regulation of locomotionGO:00400121480.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
female pregnancyGO:00075651220.019
locomotionGO:00400112370.019
transmission of nerve impulseGO:0019226420.019
positive regulation of cell developmentGO:00107201760.019
multicellular organismal signalingGO:0035637440.019
reproductive system developmentGO:00614581280.018
response to external biotic stimulusGO:00432072210.018
regulation of cellular amine metabolic processGO:003323880.018
protein complex subunit organizationGO:00718223020.018
positive regulation of protein modification processGO:00314011420.018
g protein coupled receptor signaling pathwayGO:00071862420.018
blood vessel morphogenesisGO:0048514580.018
positive regulation of cellular catabolic processGO:0031331710.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
immune system processGO:00023762040.017
erythrocyte differentiationGO:003021810.017
respiratory system developmentGO:0060541450.017
response to estradiolGO:00323551640.017
anatomical structure formation involved in morphogenesisGO:0048646830.017
purine containing compound metabolic processGO:00725212530.017
cellular component morphogenesisGO:00329891550.017
regulation of neuron differentiationGO:00456642080.017
negative regulation of molecular functionGO:00440921330.017
regulation of peptide secretionGO:0002791820.017
endocytosisGO:0006897840.017
positive regulation of cellular component movementGO:00512721020.017
regulation of growthGO:00400081050.017
vasculature developmentGO:0001944700.017
regulation of cellular ketone metabolic processGO:0010565270.017
regulation of body fluid levelsGO:0050878900.017
regulation of anatomical structure sizeGO:00900661350.017
positive regulation of locomotionGO:00400171020.016
mapk cascadeGO:00001651400.016
positive regulation of cellular protein metabolic processGO:00322701670.016
response to other organismGO:00517072200.016
monocarboxylic acid metabolic processGO:00327871520.016
positive regulation of nervous system developmentGO:00519621780.016
positive regulation of protein metabolic processGO:00512471780.016
establishment of protein localizationGO:00451841410.016
negative regulation of protein metabolic processGO:00512481140.016
regulation of protein phosphorylationGO:00019321830.016
regulation of neural precursor cell proliferationGO:2000177160.016
regulation of transferase activityGO:00513381230.016
purine ribonucleoside triphosphate metabolic processGO:00092051400.016
regulation of cellular component movementGO:00512701500.016
regulation of insulin secretionGO:0050796650.016
axis specificationGO:000979840.015
negative regulation of rna metabolic processGO:00512531230.015
forebrain developmentGO:0030900980.015
positive regulation of intracellular signal transductionGO:19025331380.015
negative regulation of growthGO:0045926370.015
response to cobalt ionGO:0032025120.015
response to osmotic stressGO:0006970420.015
gastrulationGO:000736920.015
protein transportGO:00150311320.015
response to nutrientGO:00075842480.015
response to axon injuryGO:0048678590.015
regulation of cell projection organizationGO:00313441750.015
response to ethanolGO:00454711620.015
cellular ketone metabolic processGO:0042180510.015
cellular response to oxygen levelsGO:0071453600.015
regulation of vasoconstrictionGO:0019229440.015
cellular response to hexose stimulusGO:0071331650.015
response to mechanical stimulusGO:00096121340.015
neuronal action potentialGO:0019228350.015
cell motilityGO:00488702020.014
regulation of neuron projection developmentGO:00109751610.014
cell morphogenesis involved in differentiationGO:00009041190.014
positive regulation of cellular amine metabolic processGO:003324030.014
regulation of response to stressGO:00801341260.014
nucleoside phosphate metabolic processGO:00067532830.014
glycerolipid metabolic processGO:0046486670.014
glycosyl compound metabolic processGO:19016571820.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
receptor metabolic processGO:0043112180.014
positive regulation of catabolic processGO:0009896780.014
ribonucleotide metabolic processGO:00092592310.014
learningGO:0007612330.014
regulation of neuron apoptotic processGO:0043523830.014
regulation of transcription elongation from rna polymerase ii promoterGO:003424340.014
response to bacteriumGO:00096172000.014
regulation of vesicle mediated transportGO:0060627810.014
ribose phosphate metabolic processGO:00196932350.014
organophosphate biosynthetic processGO:00904071430.014
regulation of cell cycleGO:0051726730.014
potassium ion transportGO:0006813970.014
purine nucleotide metabolic processGO:00061632290.014
protein autophosphorylationGO:0046777660.014
organic anion transportGO:00157111320.013
purine ribonucleotide metabolic processGO:00091502270.013
response to campGO:0051591910.013
response to electrical stimulusGO:0051602560.013
embryonic placenta developmentGO:000189210.013
regulation of homeostatic processGO:00328441010.013
negative regulation of signal transductionGO:0009968830.013
positive regulation of protein phosphorylationGO:00019341350.013
regulation of ras protein signal transductionGO:0046578450.013
regulation of catabolic processGO:00098941130.013
organonitrogen compound catabolic processGO:19015651790.013
cell cycleGO:00070491010.013
telencephalon developmentGO:0021537620.013
positive regulation of mapk cascadeGO:0043410920.013
heterocycle catabolic processGO:00467001670.013
organelle organizationGO:00069962660.013
nucleotide metabolic processGO:00091172790.013
response to temperature stimulusGO:0009266940.013
erk1 and erk2 cascadeGO:0070371480.013
nucleoside metabolic processGO:00091161790.013
carbohydrate derivative biosynthetic processGO:19011371240.013
cellular glucose homeostasisGO:0001678660.013
dephosphorylationGO:0016311980.013
signal transduction by phosphorylationGO:00230141440.012
regulation of canonical wnt signaling pathwayGO:006082840.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
muscle cell proliferationGO:0033002840.012
carbohydrate metabolic processGO:00059751300.012
enzyme linked receptor protein signaling pathwayGO:00071671160.012
cellular macromolecule localizationGO:00707271220.012
negative regulation of neuron apoptotic processGO:0043524450.012
negative regulation of catalytic activityGO:00430861030.012
regulation of anatomical structure morphogenesisGO:00226031410.012
response to activityGO:0014823730.012
hormone metabolic processGO:0042445690.012
axon developmentGO:0061564960.012
cellular response to inorganic substanceGO:0071241650.012
cellular response to glucose stimulusGO:0071333650.012
positive regulation of ion transportGO:0043270940.012
tissue remodelingGO:0048771400.012
wound healingGO:00420601220.012
anterior posterior pattern specificationGO:000995210.012
divalent inorganic cation transportGO:00725111340.012
regulation of phosphorus metabolic processGO:00511743490.012
regulation of synaptic transmissionGO:00508041410.012
tube formationGO:003514830.012
regulation of nucleotide metabolic processGO:00061401170.012
chromosome segregationGO:000705920.012
muscle system processGO:00030121150.012
cellular response to reactive oxygen speciesGO:0034614550.012
oxidation reduction processGO:00551143040.012
cellular response to abiotic stimulusGO:0071214850.012
nucleotide catabolic processGO:00091661390.012
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
cellular response to carbohydrate stimulusGO:0071322720.012
embryonic pattern specificationGO:000988010.011
sodium ion transportGO:0006814820.011
intracellular protein transportGO:0006886790.011
sensory organ developmentGO:0007423740.011
positive regulation of insulin secretionGO:0032024360.011
cell adhesionGO:00071551100.011
actin filament based processGO:0030029860.011
associative learningGO:0008306190.011
motor neuron axon guidanceGO:000804510.011
camera type eye developmentGO:0043010480.011
axon ensheathmentGO:0008366400.011
negative regulation of secretion by cellGO:1903531720.011
regulation of protein kinase activityGO:00458591050.011
erythrocyte homeostasisGO:003410120.011
amino acid transportGO:0006865700.011
eye morphogenesisGO:004859240.011
cellular response to corticosteroid stimulusGO:0071384690.011
digestive system developmentGO:0055123410.011
rhythmic processGO:00485111560.011
positive regulation of cellular component organizationGO:00511302000.011
morphogenesis of an epitheliumGO:0002009200.011
purine nucleoside metabolic processGO:00422781690.011
organic acid transportGO:00158491160.011
negative regulation of cell developmentGO:0010721820.011
male gamete generationGO:0048232990.011
smooth muscle cell proliferationGO:0048659770.011
aromatic compound catabolic processGO:00194391680.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
organic cyclic compound catabolic processGO:19013611750.011
insulin secretionGO:0030073690.011
positive regulation of cytokine productionGO:0001819420.011
mesoderm developmentGO:000749820.011
lymphocyte homeostasisGO:000226020.010
reactive nitrogen species metabolic processGO:200105710.010
reactive oxygen species biosynthetic processGO:190340980.010
positive regulation of purine nucleotide metabolic processGO:1900544910.010
spermatogenesisGO:0007283990.010
purine ribonucleoside metabolic processGO:00461281680.010
nucleobase containing compound catabolic processGO:00346551520.010
regulation of necroptotic processGO:006054420.010
positive regulation of nucleotide metabolic processGO:0045981910.010
cellular response to lipopolysaccharideGO:0071222550.010
negative regulation of cellular component organizationGO:0051129830.010
immune responseGO:00069551040.010
calcium ion transportGO:00068161310.010
regulation of synaptic plasticityGO:0048167700.010
tube developmentGO:0035295890.010
cytoplasmic transportGO:00164821150.010
tissue morphogenesisGO:0048729220.010
sodium ion transmembrane transportGO:0035725670.010
divalent inorganic cation homeostasisGO:00725071650.010
negative regulation of intracellular signal transductionGO:1902532380.010
cardiac chamber developmentGO:000320510.010
negative regulation of phosphate metabolic processGO:0045936800.010

Vhl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.027
disease of anatomical entityDOID:700.027
organ system cancerDOID:005068600.017
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
sensory system diseaseDOID:005015500.015
musculoskeletal system diseaseDOID:1700.010