Rattus norvegicus

0 known processes

Trhde

thyrotropin-releasing hormone degrading enzyme

(Aliases: PAP-II)

Trhde biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron developmentGO:00486662860.221
neuron differentiationGO:00301823680.152
cell projection organizationGO:00300303020.147
cell migrationGO:00164771970.136
reproductive processGO:00224143720.130
regulation of cellular component organizationGO:00511283680.125
brain developmentGO:00074202470.117
regulation of nervous system developmentGO:00519602640.113
regulation of rna metabolic processGO:00512523910.111
cellular component assemblyGO:00226073600.111
head developmentGO:00603222470.110
positive regulation of multicellular organismal processGO:00512403870.104
cellular component morphogenesisGO:00329891550.098
transmembrane transportGO:00550854120.098
protein complex subunit organizationGO:00718223020.098
cellular response to endogenous stimulusGO:00714953770.096
reproductionGO:00000032450.090
Fly
rna biosynthetic processGO:00327743800.089
rhythmic processGO:00485111560.088
single organism reproductive processGO:00447022970.086
cell morphogenesisGO:00009021420.085
regulation of cell proliferationGO:00421273590.081
regulation of cell differentiationGO:00455953200.079
transcription dna templatedGO:00063513770.078
regulation of phosphate metabolic processGO:00192203490.077
response to extracellular stimulusGO:00099913800.076
cation transportGO:00068123820.076
cellular component movementGO:00069282480.076
response to acid chemicalGO:00011012220.074
protein oligomerizationGO:00512591910.074
dendrite developmentGO:0016358720.074
neuron projection developmentGO:00311752730.073
transcription from rna polymerase ii promoterGO:00063662520.073
g protein coupled receptor signaling pathwayGO:00071862420.073
Rat
regulation of transcription dna templatedGO:00063553740.072
rna metabolic processGO:00160704060.071
regulation of cellular component movementGO:00512701500.069
regulation of rna biosynthetic processGO:20011413810.069
multicellular organism reproductionGO:00325042330.069
Fly
apoptotic processGO:00069153810.069
central nervous system developmentGO:00074173110.068
regulation of multicellular organismal developmentGO:20000263760.068
anatomical structure morphogenesisGO:00096532980.068
macromolecular complex assemblyGO:00650032730.068
response to nutrient levelsGO:00316673700.067
organic acid metabolic processGO:00060822920.065
positive regulation of nitrogen compound metabolic processGO:00511733340.065
cellular response to nitrogen compoundGO:19016992100.064
cellular component biogenesisGO:00440853680.063
positive regulation of developmental processGO:00510942830.063
cellular response to organic cyclic compoundGO:00714072020.063
programmed cell deathGO:00125013920.062
developmental process involved in reproductionGO:00030061590.061
single organism biosynthetic processGO:00447113420.061
negative regulation of multicellular organismal processGO:00512412030.059
Rat
multicellular organismal reproductive processGO:00486092330.059
intracellular signal transductionGO:00355563140.058
macromolecular complex subunit organizationGO:00439333390.058
positive regulation of molecular functionGO:00440932300.057
protein complex assemblyGO:00064612630.056
regulation of phosphorus metabolic processGO:00511743490.056
regulation of neuron projection developmentGO:00109751610.055
regulation of nucleic acid templated transcriptionGO:19035063800.054
positive regulation of biosynthetic processGO:00098913190.053
regulation of neuron differentiationGO:00456642080.052
locomotionGO:00400112370.052
cell projection morphogenesisGO:00488581230.051
regulation of apoptotic processGO:00429813350.050
cell motilityGO:00488702020.050
regulation of transcription from rna polymerase ii promoterGO:00063572340.050
positive regulation of cellular biosynthetic processGO:00313282950.049
ovulation cycleGO:0042698670.049
response to histamineGO:003477630.049
response to nutrientGO:00075842480.048
cell cell signalingGO:00072673350.048
Rat Fly
organic substance catabolic processGO:19015753160.048
Rat
response to peptide hormoneGO:00434342780.048
neurological system processGO:00508772190.047
regulation of membrane potentialGO:00423911100.047
localization of cellGO:00516742020.047
response to inorganic substanceGO:00100353770.046
female pregnancyGO:00075651220.046
positive regulation of cell differentiationGO:00455972170.045
protein complex biogenesisGO:00702712630.045
catabolic processGO:00090563510.045
Rat
protein heterooligomerizationGO:0051291890.044
negative regulation of cell deathGO:00605482290.044
neuron neuron synaptic transmissionGO:0007270600.044
carboxylic acid metabolic processGO:00197522890.044
response to estrogenGO:00436272320.043
homeostatic processGO:00425923310.043
Rat
regulation of ion transportGO:00432692450.043
positive regulation of cell communicationGO:00106472710.043
ion transmembrane transportGO:00342203650.043
regulation of anatomical structure sizeGO:00900661350.042
positive regulation of cellular component organizationGO:00511302000.042
cell part morphogenesisGO:00329901230.042
amine metabolic processGO:0009308380.042
adult locomotory behaviorGO:000834440.042
synaptic transmission gabaergicGO:0051932220.042
cellular amine metabolic processGO:0044106380.041
response to woundingGO:00096112540.041
response to monosaccharideGO:00342841590.041
metal ion transportGO:00300012890.041
positive regulation of gene expressionGO:00106282440.040
tissue developmentGO:00098882520.040
regulation of cell projection organizationGO:00313441750.039
secretionGO:00469033070.039
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.038
regulation of programmed cell deathGO:00430673410.038
regulation of signal transductionGO:00099663180.037
positive regulation of nervous system developmentGO:00519621780.037
positive regulation of programmed cell deathGO:00430681570.037
nitrogen compound transportGO:00717052290.037
nucleic acid templated transcriptionGO:00976593790.036
neuron projection morphogenesisGO:00488121220.036
purine containing compound metabolic processGO:00725212530.036
positive regulation of cell developmentGO:00107201760.036
cellular response to oxygen containing compoundGO:19017013860.036
regulation of cell migrationGO:00303341280.036
multi organism reproductive processGO:00447032620.036
positive regulation of neuron projection developmentGO:0010976990.036
cell morphogenesis involved in differentiationGO:00009041190.036
response to oxygen levelsGO:00704822650.035
macromolecule localizationGO:00330362520.035
regulation of neurogenesisGO:00507672470.035
multicellular organismal signalingGO:0035637440.034
positive regulation of locomotionGO:00400171020.034
cellular homeostasisGO:00197252520.034
regulation of cell motilityGO:20001451310.034
synaptic transmissionGO:00072682350.034
Rat
positive regulation of phosphate metabolic processGO:00459372620.033
organic acid transportGO:00158491160.033
cellular chemical homeostasisGO:00550822470.033
positive regulation of transportGO:00510502450.032
response to hypoxiaGO:00016662310.032
purine nucleotide metabolic processGO:00061632290.032
negative regulation of nervous system developmentGO:0051961790.031
oxoacid metabolic processGO:00434362900.031
response to mechanical stimulusGO:00096121340.031
negative regulation of apoptotic processGO:00430661810.031
reproductive structure developmentGO:00486081280.030
response to ketoneGO:19016541820.030
potassium ion transportGO:0006813970.030
carboxylic acid transportGO:00469421150.030
nucleobase containing small molecule metabolic processGO:00550863160.029
response to hexoseGO:00097461440.029
cell growthGO:00160491040.029
positive regulation of neuron differentiationGO:00456661260.029
positive regulation of signalingGO:00230562700.029
vesicle mediated transportGO:00161921810.029
Fly
chemical homeostasisGO:00488782920.029
Rat
sexual reproductionGO:00199531480.029
regulation of cellular amine metabolic processGO:003323880.029
positive regulation of neurogenesisGO:00507691650.029
heart morphogenesisGO:000300730.029
developmental growthGO:00485891000.028
endocytosisGO:0006897840.028
Fly
nucleotide metabolic processGO:00091172790.028
peptide transportGO:0015833970.028
response to peptideGO:19016522920.028
sensory perceptionGO:00076001010.028
regulation of cell developmentGO:00602842630.028
reproductive system developmentGO:00614581280.028
negative regulation of cell developmentGO:0010721820.028
regulation of phosphorylationGO:00423252480.028
regulation of intracellular signal transductionGO:19025312180.028
regulation of locomotionGO:00400121480.027
divalent inorganic cation homeostasisGO:00725071650.027
proteolysisGO:00065081750.027
Rat
action potentialGO:0001508540.027
carbohydrate derivative metabolic processGO:19011353460.027
positive regulation of protein metabolic processGO:00512471780.027
negative regulation of cellular metabolic processGO:00313242810.026
positive regulation of catalytic activityGO:00430851840.026
organophosphate metabolic processGO:00196373700.026
response to growth factorGO:00708481890.026
response to vitaminGO:00332731310.026
regulation of dendrite developmentGO:0050773590.026
cellular amino acid metabolic processGO:00065201070.026
cytosolic calcium ion homeostasisGO:00514801400.026
negative regulation of cell communicationGO:00106481580.026
positive regulation of rna metabolic processGO:00512542030.026
negative regulation of metabolic processGO:00098923310.026
protein localizationGO:00081041910.026
regulation of synaptic transmission glutamatergicGO:0051966260.026
response to toxic substanceGO:00096361330.026
circadian rhythmGO:0007623880.025
positive regulation of phosphorus metabolic processGO:00105622620.025
positive regulation of cell deathGO:00109421840.025
neuron apoptotic processGO:0051402880.025
negative regulation of cell differentiationGO:0045596990.025
regulation of purine nucleotide metabolic processGO:19005421150.025
positive regulation of cellular component movementGO:00512721020.025
response to biotic stimulusGO:00096072260.025
positive regulation of response to stimulusGO:00485842850.025
regulation of cell morphogenesisGO:0022604770.025
cell type specific apoptotic processGO:00972851340.025
negative regulation of signalingGO:00230571570.025
forebrain developmentGO:0030900980.024
regulation of cellular amino acid metabolic processGO:000652120.024
organic anion transportGO:00157111320.024
positive regulation of cell motilityGO:2000147970.024
calcium ion homeostasisGO:00550741620.024
regulation of cellular localizationGO:00603412630.024
organelle organizationGO:00069962660.024
purine ribonucleotide metabolic processGO:00091502270.024
cellular response to hormone stimulusGO:00328702470.024
axon developmentGO:0061564960.023
neuron deathGO:00709971270.023
sex differentiationGO:00075481130.023
response to glucoseGO:00097491360.023
negative regulation of programmed cell deathGO:00430691830.023
gastrulationGO:000736920.023
agingGO:00075682410.023
regulation of secretion by cellGO:19035302080.023
positive regulation of cell projection organizationGO:00313461110.023
growthGO:00400071650.023
nucleoside phosphate metabolic processGO:00067532830.023
negative regulation of neuron differentiationGO:0045665620.023
positive regulation of ion transportGO:0043270940.023
gonad developmentGO:00084061040.023
positive regulation of transcription dna templatedGO:00458931970.022
multi multicellular organism processGO:00447061380.022
secretion by cellGO:00329402480.022
development of primary sexual characteristicsGO:00451371070.022
positive regulation of purine nucleotide metabolic processGO:1900544910.022
regulation of nucleotide metabolic processGO:00061401170.022
single organism organelle organizationGO:19025891800.022
regulation of system processGO:00440572080.022
Rat
ras protein signal transductionGO:0007265290.022
cell morphogenesis involved in neuron differentiationGO:00486671060.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
regulation of proteasomal protein catabolic processGO:006113640.021
cellular ion homeostasisGO:00068731840.021
cellular macromolecule localizationGO:00707271220.021
response to carbohydrateGO:00097431830.021
regulation of secretionGO:00510462240.021
Rat
negative regulation of developmental processGO:00510931250.021
cellular protein localizationGO:00346131220.021
divalent inorganic cation transportGO:00725111340.021
response to decreased oxygen levelsGO:00362932370.021
cellular lipid metabolic processGO:00442552080.020
regulation of peptide transportGO:0090087870.020
cellular catabolic processGO:00442482950.020
Rat
cell adhesionGO:00071551100.020
monovalent inorganic cation transportGO:00156721720.020
response to metal ionGO:00100382530.020
regulation of neuron deathGO:19012141150.020
anion transportGO:00068201780.020
blood circulationGO:00080151830.020
Rat
anion transmembrane transportGO:0098656770.020
chemosensory behaviorGO:000763520.020
cellular response to lipidGO:00713962010.020
protein phosphorylationGO:00064683450.020
membrane organizationGO:0061024940.020
learning or memoryGO:0007611900.020
regulation of catabolic processGO:00098941130.020
muscle system processGO:00030121150.020
cellular nitrogen compound catabolic processGO:00442701630.020
organonitrogen compound catabolic processGO:19015651790.019
Rat
calcium ion transportGO:00068161310.019
biological adhesionGO:00226101100.019
regulation of anatomical structure morphogenesisGO:00226031410.019
small gtpase mediated signal transductionGO:0007264360.019
response to ammonium ionGO:0060359710.019
regulation of epithelial cell proliferationGO:0050678490.019
regulation of cellular protein metabolic processGO:00322682670.019
cellular metal ion homeostasisGO:00068751720.019
carbohydrate derivative biosynthetic processGO:19011371240.019
regulation of molecular functionGO:00650093980.019
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of catalytic activityGO:00507903040.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
cellular response to histamineGO:007142030.019
organic hydroxy compound transportGO:0015850770.019
response to estradiolGO:00323551640.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
hormone transportGO:00099141210.018
response to cytokineGO:00340972150.018
peptide secretionGO:0002790860.018
immune system processGO:00023762040.018
regulation of synaptic transmissionGO:00508041410.018
Rat
positive regulation of apoptotic processGO:00430651540.018
lipid metabolic processGO:00066292830.018
synaptic transmission glycinergicGO:006001220.018
cardiac conductionGO:006133720.017
response to other organismGO:00517072200.017
signal transduction by phosphorylationGO:00230141440.017
cellular response to organonitrogen compoundGO:00714171970.017
response to oxidative stressGO:00069791860.017
positive regulation of protein modification processGO:00314011420.017
positive regulation of cell proliferationGO:00082842490.017
negative regulation of neurogenesisGO:0050768780.017
positive regulation of rna biosynthetic processGO:19026801970.017
behaviorGO:00076102050.017
negative regulation of macromolecule metabolic processGO:00106052600.016
cellular ketone metabolic processGO:0042180510.016
negative regulation of vascular permeabilityGO:004311630.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
cellular response to growth factor stimulusGO:00713631620.016
organic cyclic compound catabolic processGO:19013611750.016
positive regulation of macromolecule biosynthetic processGO:00105572470.016
cellular response to stressGO:00335542690.016
cell cycleGO:00070491010.016
positive regulation of cell migrationGO:0030335960.016
positive regulation of cellular protein metabolic processGO:00322701670.016
regulation of peptide secretionGO:0002791820.016
regulation of blood circulationGO:19035221100.016
multicellular organism growthGO:003526410.016
bmp signaling pathwayGO:003050940.016
synaptic growth at neuromuscular junctionGO:005112410.016
signal releaseGO:00230611450.016
organophosphate biosynthetic processGO:00904071430.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
negative regulation of transportGO:00510511360.015
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
synaptic transmission glutamatergicGO:0035249330.015
positive regulation of protein phosphorylationGO:00019341350.015
sensory organ developmentGO:0007423740.015
heterocycle catabolic processGO:00467001670.015
regulation of cyclic nucleotide metabolic processGO:0030799510.015
purine nucleoside metabolic processGO:00422781690.015
metal ion homeostasisGO:00550651860.015
Rat
ribonucleotide metabolic processGO:00092592310.015
mesoderm developmentGO:000749820.014
purine ribonucleoside metabolic processGO:00461281680.014
organonitrogen compound biosynthetic processGO:19015661670.014
formation of primary germ layerGO:000170410.014
positive regulation of cellular catabolic processGO:0031331710.014
gamete generationGO:00072761240.014
response to glucocorticoidGO:00513842230.014
regulation of protein metabolic processGO:00512462890.014
small molecule biosynthetic processGO:00442831240.014
circulatory system processGO:00030131830.014
Rat
cognitionGO:0050890920.014
response to ethanolGO:00454711620.014
regulation of cellular catabolic processGO:00313291010.014
nucleoside metabolic processGO:00091161790.014
ribose phosphate biosynthetic processGO:0046390870.014
negative regulation of cell proliferationGO:00082851190.014
alpha amino acid metabolic processGO:1901605710.014
dendrite morphogenesisGO:0048813430.014
regulation of cellular ketone metabolic processGO:0010565270.014
response to insulinGO:00328681330.014
regulation of hormone levelsGO:00108171870.014
neuronal action potentialGO:0019228350.014
negative regulation of biosynthetic processGO:00098901680.014
glycosyl compound metabolic processGO:19016571820.014
negative regulation of cellular component organizationGO:0051129830.014
negative regulation of cellular biosynthetic processGO:00313271610.014
cellular response to external stimulusGO:00714961180.014
positive regulation of blood circulationGO:1903524650.014
hormone secretionGO:00468791150.013
mapk cascadeGO:00001651400.013
circulatory system developmentGO:00723591340.013
divalent metal ion transportGO:00708381320.013
regulation of muscle system processGO:0090257790.013
response to transition metal nanoparticleGO:19902671220.013
regulation of hydrolase activityGO:00513361430.013
epithelium developmentGO:0060429960.013
response to radiationGO:00093141370.013
inner ear receptor cell differentiationGO:006011320.013
muscle structure developmentGO:0061061870.013
regulation of response to stressGO:00801341260.013
negative regulation of gene expressionGO:00106291990.013
regulation of nucleotide catabolic processGO:0030811650.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
organic acid biosynthetic processGO:0016053830.013
gland developmentGO:00487321550.013
cyclic purine nucleotide metabolic processGO:0052652620.013
dendritic spine developmentGO:0060996200.013
female sex differentiationGO:0046660590.013
nucleobase containing compound catabolic processGO:00346551520.013
negative regulation of neuron deathGO:1901215690.013
ribonucleoside metabolic processGO:00091191740.013
regulation of peptide hormone secretionGO:0090276800.013
amide transportGO:00428861050.013
response to external biotic stimulusGO:00432072210.013
positive regulation of behaviorGO:0048520380.012
single organism catabolic processGO:00447122830.012
regulation of protein phosphorylationGO:00019321830.012
central nervous system neuron differentiationGO:0021953170.012
male gamete generationGO:0048232990.012
telencephalon developmentGO:0021537620.012
ribose phosphate metabolic processGO:00196932350.012
cytoskeleton organizationGO:00070101110.012
positive regulation of calcium ion transportGO:0051928360.012
positive regulation of nucleotide metabolic processGO:0045981910.012
regulation of tube sizeGO:0035150890.012
camp metabolic processGO:0046058630.012
regulation of protein localizationGO:0032880810.012
chromosome segregationGO:000705920.012
epithelial cell migrationGO:0010631190.012
glutamate secretionGO:0014047190.012
heart processGO:0003015570.012
regulation of canonical wnt signaling pathwayGO:006082840.012
response to amino acidGO:0043200750.012
peptide hormone secretionGO:0030072840.012
axonogenesisGO:0007409710.012
ion homeostasisGO:00508012120.012
Rat
learningGO:0007612330.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cellular response to alcoholGO:0097306870.012
ovulation cycle processGO:0022602500.012
negative regulation of organ growthGO:004662130.012
response to corticosteroidGO:00319602350.012
embryo developmentGO:0009790490.012
regulation of respiratory system processGO:004406510.012
regulation of metal ion transportGO:00109591180.012
negative regulation of synaptic transmission glutamatergicGO:005196780.012
urinary tract smooth muscle contractionGO:001484840.012
reactive oxygen species metabolic processGO:0072593370.012
peptidyl amino acid modificationGO:00181931260.012
enzyme linked receptor protein signaling pathwayGO:00071671160.011
negative regulation of canonical wnt signaling pathwayGO:009009040.011
regulation of gtpase activityGO:0043087570.011
negative regulation of transcription dna templatedGO:00458921160.011
regulation of cell growthGO:0001558850.011
positive regulation of signal transductionGO:00099671750.011
regulation of growthGO:00400081050.011
actin filament based processGO:0030029860.011
acid secretionGO:0046717480.011
response to retinoic acidGO:0032526630.011
cellular response to ammonium ionGO:0071242170.011
negative regulation of phosphate metabolic processGO:0045936800.011
lipid biosynthetic processGO:00086101280.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
gliogenesisGO:0042063930.011
negative regulation of phosphorus metabolic processGO:0010563800.011
regulation of cellular component biogenesisGO:0044087860.011
sulfur compound metabolic processGO:0006790700.011
morphogenesis of embryonic epitheliumGO:001633130.011
embryonic pattern specificationGO:000988010.011
nucleoside triphosphate metabolic processGO:00091411440.011
spermatogenesisGO:0007283990.011
single organism behaviorGO:00447081300.011
response to bacteriumGO:00096172000.011
muscle tissue developmentGO:0060537580.011
positive regulation of phosphorylationGO:00423271770.011
response to progesteroneGO:0032570480.011
amino acid transportGO:0006865700.011
aromatic compound catabolic processGO:00194391680.011
cellular calcium ion homeostasisGO:00068741600.011
positive regulation of intracellular signal transductionGO:19025331380.011
reactive nitrogen species metabolic processGO:200105710.011
cyclic nucleotide metabolic processGO:0009187800.011
regulation of stem cell differentiationGO:200073620.011
positive regulation of secretion by cellGO:19035321280.011
alcohol metabolic processGO:0006066770.011
organic acid catabolic processGO:0016054490.011
positive regulation of growthGO:0045927550.011
response to purine containing compoundGO:00140741260.011
organic hydroxy compound metabolic processGO:19016151150.011
inorganic cation transmembrane transportGO:00986622020.011
cardiovascular system developmentGO:00723581340.011
regulation of reactive oxygen species metabolic processGO:2000377260.011
cell communication involved in cardiac conductionGO:008606520.011
rho protein signal transductionGO:0007266110.010
cell cycle checkpointGO:000007520.010
positive regulation of hydrolase activityGO:0051345860.010
axis specificationGO:000979840.010
organ morphogenesisGO:0009887750.010
developmental growth involved in morphogenesisGO:0060560330.010
cellular response to corticosteroid stimulusGO:0071384690.010
vascular process in circulatory systemGO:0003018960.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
maternal process involved in female pregnancyGO:0060135380.010
neuromuscular processGO:005090520.010
dna metabolic processGO:0006259960.010
carbohydrate homeostasisGO:0033500750.010
epithelial cell differentiationGO:0030855710.010
cellular cation homeostasisGO:00300031800.010
spinal cord developmentGO:0021510270.010
motor neuron axon guidanceGO:000804510.010
regulation of hormone secretionGO:00468831060.010
negative regulation of stress activated protein kinase signaling cascadeGO:007030340.010
purine containing compound catabolic processGO:00725231380.010
protein localization to organelleGO:0033365570.010
regulation of synaptic plasticityGO:0048167700.010
Rat

Trhde disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
nervous system diseaseDOID:86300.059
central nervous system diseaseDOID:33100.029
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024
epilepsy syndromeDOID:182600.021
brain diseaseDOID:93600.021
organ system cancerDOID:005068600.013