Rattus norvegicus

168 known processes

Mtor

mechanistic target of rapamycin (serine/threonine kinase)

(Aliases: RAFT1,Frap1)

Mtor biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein complex biogenesisGO:00702712630.074
macromolecular complex assemblyGO:00650032730.070
positive regulation of phosphorus metabolic processGO:00105622620.067
Human
intracellular signal transductionGO:00355563140.062
cellular response to endogenous stimulusGO:00714953770.060
protein complex assemblyGO:00064612630.058
macromolecular complex subunit organizationGO:00439333390.055
brain developmentGO:00074202470.053
organelle organizationGO:00069962660.053
Human
cellular component biogenesisGO:00440853680.051
single organism catabolic processGO:00447122830.049
cellular component assemblyGO:00226073600.048
protein complex subunit organizationGO:00718223020.046
carboxylic acid metabolic processGO:00197522890.045
organonitrogen compound catabolic processGO:19015651790.045
reproductive processGO:00224143720.045
regulation of protein metabolic processGO:00512462890.045
response to oxygen levelsGO:00704822650.043
regulation of phosphate metabolic processGO:00192203490.043
Human
cellular response to stressGO:00335542690.042
oxoacid metabolic processGO:00434362900.042
ion transmembrane transportGO:00342203650.042
central nervous system developmentGO:00074173110.041
single organism reproductive processGO:00447022970.041
response to decreased oxygen levelsGO:00362932370.041
homeostatic processGO:00425923310.041
regulation of cell differentiationGO:00455953200.040
head developmentGO:00603222470.039
positive regulation of phosphate metabolic processGO:00459372620.039
Human
carbohydrate derivative metabolic processGO:19011353460.039
positive regulation of nitrogen compound metabolic processGO:00511733340.038
Human
negative regulation of metabolic processGO:00098923310.038
negative regulation of cellular metabolic processGO:00313242810.037
negative regulation of macromolecule metabolic processGO:00106052600.036
regulation of phosphorus metabolic processGO:00511743490.036
Human
positive regulation of multicellular organismal processGO:00512403870.036
negative regulation of gene expressionGO:00106291990.036
apoptotic processGO:00069153810.034
regulation of multicellular organismal developmentGO:20000263760.034
reproductionGO:00000032450.034
regulation of neuron differentiationGO:00456642080.033
protein phosphorylationGO:00064683450.033
nucleoside phosphate metabolic processGO:00067532830.033
nucleobase containing small molecule metabolic processGO:00550863160.032
catabolic processGO:00090563510.032
single organism organelle organizationGO:19025891800.032
Human
regulation of nervous system developmentGO:00519602640.032
purine ribonucleotide metabolic processGO:00091502270.032
response to acid chemicalGO:00011012220.032
Human
multicellular organismal reproductive processGO:00486092330.031
response to metal ionGO:00100382530.031
multicellular organism reproductionGO:00325042330.031
ras protein signal transductionGO:0007265290.031
transmembrane transportGO:00550854120.031
response to hypoxiaGO:00016662310.031
regulation of neuron projection developmentGO:00109751610.030
regulation of cellular component organizationGO:00511283680.030
Human
organic cyclic compound catabolic processGO:19013611750.029
organophosphate metabolic processGO:00196373700.029
nucleotide metabolic processGO:00091172790.029
response to amino acidGO:0043200750.029
Human
regulation of signal transductionGO:00099663180.028
sexual reproductionGO:00199531480.028
neuron differentiationGO:00301823680.028
circulatory system processGO:00030131830.028
regulation of programmed cell deathGO:00430673410.028
rna metabolic processGO:00160704060.027
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.027
nucleic acid templated transcriptionGO:00976593790.027
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.027
negative regulation of cellular component organizationGO:0051129830.027
regulation of transcription dna templatedGO:00063553740.026
Human
cellular catabolic processGO:00442482950.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
Human
calcium ion homeostasisGO:00550741620.026
positive regulation of molecular functionGO:00440932300.026
gamete generationGO:00072761240.026
multi organism reproductive processGO:00447032620.026
response to nutrientGO:00075842480.025
purine ribonucleoside catabolic processGO:00461301240.025
purine nucleoside catabolic processGO:00061521240.025
chemical homeostasisGO:00488782920.025
cell migrationGO:00164771970.025
cellular homeostasisGO:00197252520.025
regulation of cell developmentGO:00602842630.025
tissue developmentGO:00098882520.025
cation transportGO:00068123820.024
regulation of molecular functionGO:00650093980.024
ribonucleoside catabolic processGO:00424541260.024
organic substance catabolic processGO:19015753160.024
cellular amino acid metabolic processGO:00065201070.024
growthGO:00400071650.024
Human
negative regulation of biosynthetic processGO:00098901680.024
negative regulation of cell deathGO:00605482290.024
response to extracellular stimulusGO:00099913800.024
organic acid metabolic processGO:00060822920.023
regulation of nucleic acid templated transcriptionGO:19035063800.023
Human
oxidation reduction processGO:00551143040.023
response to inorganic substanceGO:00100353770.023
positive regulation of transportGO:00510502450.023
regulation of cell proliferationGO:00421273590.023
cellular amine metabolic processGO:0044106380.023
regulation of cell projection organizationGO:00313441750.023
regulation of apoptotic processGO:00429813350.023
nucleotide catabolic processGO:00091661390.023
positive regulation of signalingGO:00230562700.023
cell cycleGO:00070491010.022
rna biosynthetic processGO:00327743800.022
Human
purine nucleoside metabolic processGO:00422781690.022
purine ribonucleoside metabolic processGO:00461281680.022
neuron projection developmentGO:00311752730.022
ion homeostasisGO:00508012120.022
cellular response to nitrogen compoundGO:19016992100.022
chromosome segregationGO:000705920.022
positive regulation of nucleotide metabolic processGO:0045981910.022
organophosphate catabolic processGO:00464341480.022
response to ethanolGO:00454711620.022
negative regulation of programmed cell deathGO:00430691830.022
response to carbohydrateGO:00097431830.022
ribose phosphate metabolic processGO:00196932350.022
purine containing compound metabolic processGO:00725212530.022
regulation of cellular catabolic processGO:00313291010.022
neuron developmentGO:00486662860.022
nucleoside triphosphate catabolic processGO:00091431230.021
cellular nitrogen compound catabolic processGO:00442701630.021
response to oxidative stressGO:00069791860.021
glycosyl compound catabolic processGO:19016581260.021
response to nutrient levelsGO:00316673700.021
synaptic transmissionGO:00072682350.021
cellular ketone metabolic processGO:0042180510.021
carbohydrate derivative catabolic processGO:19011361470.021
regulation of neurogenesisGO:00507672470.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
transcription dna templatedGO:00063513770.021
Human
positive regulation of developmental processGO:00510942830.021
purine nucleotide catabolic processGO:00061951360.021
cellular chemical homeostasisGO:00550822470.021
cation transmembrane transportGO:00986552630.020
cell projection organizationGO:00300303020.020
purine nucleoside triphosphate catabolic processGO:00091461220.020
regulation of catalytic activityGO:00507903040.020
inorganic ion transmembrane transportGO:00986602290.020
regulation of system processGO:00440572080.020
regulation of purine nucleotide catabolic processGO:0033121650.020
positive regulation of nervous system developmentGO:00519621780.020
aromatic compound catabolic processGO:00194391680.020
ribonucleoside metabolic processGO:00091191740.020
guanosine containing compound metabolic processGO:1901068740.020
positive regulation of purine nucleotide metabolic processGO:1900544910.020
blood circulationGO:00080151830.020
purine ribonucleoside triphosphate catabolic processGO:00092071220.019
nucleoside phosphate catabolic processGO:19012921400.019
regulation of cellular amino acid metabolic processGO:000652120.019
localization of cellGO:00516742020.019
regulation of cell cycleGO:0051726730.019
single organism biosynthetic processGO:00447113420.019
translationGO:0006412350.019
amine metabolic processGO:0009308380.019
glycosyl compound metabolic processGO:19016571820.019
cellular response to growth factor stimulusGO:00713631620.019
positive regulation of neurogenesisGO:00507691650.019
reactive oxygen species metabolic processGO:0072593370.019
positive regulation of cell developmentGO:00107201760.019
positive regulation of response to stimulusGO:00485842850.019
cellular component morphogenesisGO:00329891550.019
ribonucleotide metabolic processGO:00092592310.019
cell cell signalingGO:00072673350.019
negative regulation of nitrogen compound metabolic processGO:00511721610.018
ribonucleotide catabolic processGO:00092611360.018
cytoplasmic transportGO:00164821150.018
cell adhesionGO:00071551100.018
regulation of nucleotide metabolic processGO:00061401170.018
cellular cation homeostasisGO:00300031800.018
heterocycle catabolic processGO:00467001670.018
regulation of cell migrationGO:00303341280.018
response to estrogenGO:00436272320.018
dna metabolic processGO:0006259960.018
regulation of hydrolase activityGO:00513361430.018
positive regulation of cellular catabolic processGO:0031331710.018
multicellular organism growthGO:003526410.018
positive regulation of cellular component organizationGO:00511302000.018
cellular ion homeostasisGO:00068731840.018
small gtpase mediated signal transductionGO:0007264360.018
negative regulation of protein metabolic processGO:00512481140.017
positive regulation of catalytic activityGO:00430851840.017
circulatory system developmentGO:00723591340.017
response to peptideGO:19016522920.017
programmed cell deathGO:00125013920.017
purine ribonucleotide catabolic processGO:00091541360.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
protein oligomerizationGO:00512591910.017
cellular response to hormone stimulusGO:00328702470.017
negative regulation of apoptotic processGO:00430661810.017
positive regulation of cellular biosynthetic processGO:00313282950.017
divalent inorganic cation homeostasisGO:00725071650.017
axis specificationGO:000979840.017
cardiovascular system developmentGO:00723581340.017
positive regulation of cell proliferationGO:00082842490.017
gland developmentGO:00487321550.017
cellular response to organonitrogen compoundGO:00714171970.017
macromolecule localizationGO:00330362520.016
regulation of cell motilityGO:20001451310.016
proteolysisGO:00065081750.016
response to glucoseGO:00097491360.016
regulation of intracellular signal transductionGO:19025312180.016
vesicle mediated transportGO:00161921810.016
nucleoside triphosphate metabolic processGO:00091411440.016
nucleoside catabolic processGO:00091641260.016
positive regulation of protein metabolic processGO:00512471780.016
regulation of neuron deathGO:19012141150.016
regulation of cellular component biogenesisGO:0044087860.016
neuronal action potentialGO:0019228350.016
response to external biotic stimulusGO:00432072210.016
defense responseGO:00069521940.016
anterior posterior pattern specificationGO:000995210.016
positive regulation of cellular protein metabolic processGO:00322701670.016
g protein coupled receptor signaling pathwayGO:00071862420.016
positive regulation of hydrolase activityGO:0051345860.016
regulation of purine nucleotide metabolic processGO:19005421150.016
response to hexoseGO:00097461440.016
anion transmembrane transportGO:0098656770.016
regulation of anatomical structure morphogenesisGO:00226031410.016
regulation of nucleotide catabolic processGO:0030811650.016
intracellular transportGO:00469071850.016
positive regulation of biosynthetic processGO:00098913190.016
negative regulation of multicellular organismal processGO:00512412030.016
positive regulation of cell differentiationGO:00455972170.016
guanosine containing compound catabolic processGO:1901069710.016
regulation of phosphorylationGO:00423252480.015
Human
regulation of rna metabolic processGO:00512523910.015
Human
response to growth factorGO:00708481890.015
cellular macromolecule localizationGO:00707271220.015
cellular component movementGO:00069282480.015
vasculogenesisGO:000157030.015
negative regulation of response to stimulusGO:00485851550.015
nucleobase containing compound catabolic processGO:00346551520.015
positive regulation of gene expressionGO:00106282440.015
peptidyl amino acid modificationGO:00181931260.015
Human
single organism intracellular transportGO:19025821660.015
regulation of reactive oxygen species metabolic processGO:2000377260.015
anatomical structure morphogenesisGO:00096532980.015
response to reactive oxygen speciesGO:00003021200.015
positive regulation of neuron differentiationGO:00456661260.015
nitrogen compound transportGO:00717052290.015
regulation of cellular amine metabolic processGO:003323880.015
regulation of cellular ketone metabolic processGO:0010565270.015
heart morphogenesisGO:000300730.015
cellular metal ion homeostasisGO:00068751720.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
cellular response to oxygen containing compoundGO:19017013860.014
metal ion transportGO:00300012890.014
gastrulationGO:000736920.014
purine nucleotide metabolic processGO:00061632290.014
metal ion homeostasisGO:00550651860.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
cation homeostasisGO:00550801950.014
regulation of rna biosynthetic processGO:20011413810.014
Human
positive regulation of cellular amino acid metabolic processGO:004576410.014
nucleoside metabolic processGO:00091161790.014
regulation of cellular localizationGO:00603412630.014
oligopeptide transportGO:000685740.014
negative regulation of nervous system developmentGO:0051961790.014
regulation of nucleoside metabolic processGO:0009118660.014
secretionGO:00469033070.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
positive regulation of cellular amine metabolic processGO:003324030.014
rho protein signal transductionGO:0007266110.014
spindle organizationGO:000705120.014
cytosolic calcium ion homeostasisGO:00514801400.014
regulation of cell growthGO:0001558850.014
inorganic cation transmembrane transportGO:00986622020.014
synaptic growth at neuromuscular junctionGO:005112410.014
response to glucocorticoidGO:00513842230.013
establishment of protein localizationGO:00451841410.013
response to monosaccharideGO:00342841590.013
protein transportGO:00150311320.013
single organism carbohydrate metabolic processGO:00447231180.013
transcription from rna polymerase ii promoterGO:00063662520.013
double strand break repairGO:000630210.013
carboxylic acid transportGO:00469421150.013
epithelium developmentGO:0060429960.013
regulation of cellular protein metabolic processGO:00322682670.013
response to transition metal nanoparticleGO:19902671220.013
response to purine containing compoundGO:00140741260.013
blood vessel developmentGO:0001568690.013
negative regulation of cellular biosynthetic processGO:00313271610.013
positive regulation of transcription dna templatedGO:00458931970.013
Human
signal transduction by phosphorylationGO:00230141440.013
protein heterooligomerizationGO:0051291890.013
cellular protein localizationGO:00346131220.013
cellular calcium ion homeostasisGO:00068741600.013
positive regulation of nucleotide catabolic processGO:0030813530.013
cell growthGO:00160491040.013
Human
reactive oxygen species biosynthetic processGO:190340980.013
response to woundingGO:00096112540.013
negative regulation of cell communicationGO:00106481580.013
meiotic cell cycle processGO:190304630.013
positive regulation of purine nucleotide catabolic processGO:0033123530.013
positive regulation of nucleoside metabolic processGO:0045979550.013
chromatin assembly or disassemblyGO:000633310.013
neuron deathGO:00709971270.013
anion transportGO:00068201780.013
cell motilityGO:00488702020.012
negative regulation of cellular protein metabolic processGO:00322691060.012
positive regulation of neuron projection developmentGO:0010976990.012
spermatogenesisGO:0007283990.012
negative regulation of organ growthGO:004662130.012
regulation of hormone levelsGO:00108171870.012
regulation of homeostatic processGO:00328441010.012
regulation of secretion by cellGO:19035302080.012
response to estradiolGO:00323551640.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.012
developmental growthGO:00485891000.012
mitotic spindle organizationGO:000705220.012
regulation of cellular response to stressGO:0080135490.012
negative regulation of rna biosynthetic processGO:19026791180.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
amide transportGO:00428861050.012
regulation of anatomical structure sizeGO:00900661350.012
lipid biosynthetic processGO:00086101280.012
Human
positive regulation of cellular component movementGO:00512721020.012
purine containing compound catabolic processGO:00725231380.012
negative regulation of cell developmentGO:0010721820.012
agingGO:00075682410.012
gliogenesisGO:0042063930.012
response to toxic substanceGO:00096361330.012
regulation of gtpase activityGO:0043087570.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
secretion by cellGO:00329402480.012
lens fiber cell differentiationGO:007030630.012
response to cytokineGO:00340972150.012
regulation of ion transmembrane transportGO:00347651210.012
positive regulation of phosphorylationGO:00423271770.012
Human
protein localizationGO:00081041910.012
regulation of catabolic processGO:00098941130.012
response to lipopolysaccharideGO:00324961910.011
behaviorGO:00076102050.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
signal releaseGO:00230611450.011
membrane organizationGO:0061024940.011
cellular divalent inorganic cation homeostasisGO:00725031620.011
lipid metabolic processGO:00066292830.011
microtubule organizing center organizationGO:003102310.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
negative regulation of cell differentiationGO:0045596990.011
cell type specific apoptotic processGO:00972851340.011
cellular lipid metabolic processGO:00442552080.011
regulation of blood circulationGO:19035221100.011
response to corticosteroidGO:00319602350.011
regulation of cellular component movementGO:00512701500.011
organic acid transportGO:00158491160.011
male gamete generationGO:0048232990.011
neuron projection morphogenesisGO:00488121220.011
myoblast fusionGO:000752020.011
lung developmentGO:0030324430.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
Human
multicellular organismal signalingGO:0035637440.011
regulation of protein modification processGO:00313991940.011
Human
response to other organismGO:00517072200.011
response to starvationGO:0042594590.011
transforming growth factor beta receptor signaling pathwayGO:0007179180.011
inflammatory responseGO:00069541500.011
positive regulation of rna metabolic processGO:00512542030.010
Human
positive regulation of cell deathGO:00109421840.010
divalent inorganic cation transportGO:00725111340.010
nuclear transportGO:0051169490.010
reactive nitrogen species metabolic processGO:200105710.010
tube developmentGO:0035295890.010
embryonic pattern specificationGO:000988010.010
neurological system processGO:00508772190.010
posttranscriptional regulation of gene expressionGO:0010608370.010
response to bacteriumGO:00096172000.010
cellular response to organic cyclic compoundGO:00714072020.010
positive regulation of rna biosynthetic processGO:19026801970.010
Human
response to peptide hormoneGO:00434342780.010
negative regulation of molecular functionGO:00440921330.010
regulation of small gtpase mediated signal transductionGO:0051056480.010
positive regulation of cell motilityGO:2000147970.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010

Mtor disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
nervous system diseaseDOID:86300.020
musculoskeletal system diseaseDOID:1700.018
disease of metabolismDOID:001466700.017
central nervous system diseaseDOID:33100.011
inherited metabolic disorderDOID:65500.010