Rattus norvegicus

0 known processes

Cyp2c12

cytochrome P450, family 2, subfamily c, polypeptide 12

(Aliases: RATP4515B8,P450pb1,Cyp2c40,RATP4515B2)

Cyp2c12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to estrogenGO:00436272320.549
cellular response to endogenous stimulusGO:00714953770.414
response to xenobiotic stimulusGO:0009410230.356
response to bacteriumGO:00096172000.355
single organism catabolic processGO:00447122830.332
cellular response to organonitrogen compoundGO:00714171970.307
oxoacid metabolic processGO:00434362900.300
response to other organismGO:00517072200.273
response to nutrientGO:00075842480.241
cellular response to steroid hormone stimulusGO:0071383930.214
defense responseGO:00069521940.210
response to oxygen levelsGO:00704822650.208
xenobiotic catabolic processGO:004217870.207
cellular catabolic processGO:00442482950.205
response to biotic stimulusGO:00096072260.193
catabolic processGO:00090563510.173
negative regulation of response to tumor cellGO:000283520.172
halogenated hydrocarbon metabolic processGO:004219740.171
aromatic compound catabolic processGO:00194391680.162
natural killer cell mediated immune response to tumor cellGO:000242310.159
cellular response to peptideGO:19016531330.157
organic acid metabolic processGO:00060822920.157
alpha amino acid metabolic processGO:1901605710.155
chlorinated hydrocarbon metabolic processGO:004219640.147
cellular response to oxygen containing compoundGO:19017013860.143
response to corticosteroidGO:00319602350.141
cellular response to lipidGO:00713962010.141
steroid metabolic processGO:0008202730.139
single organism biosynthetic processGO:00447113420.139
organic acid biosynthetic processGO:0016053830.132
cellular response to peptide hormone stimulusGO:00713751200.131
cellular response to hormone stimulusGO:00328702470.131
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.131
carboxylic acid metabolic processGO:00197522890.128
response to oxidative stressGO:00069791860.128
small molecule biosynthetic processGO:00442831240.125
organic hydroxy compound biosynthetic processGO:1901617510.119
cellular amino acid metabolic processGO:00065201070.113
oxidation reduction processGO:00551143040.111
monocarboxylic acid metabolic processGO:00327871520.111
negative regulation of immune response to tumor cellGO:000283820.103
organic substance catabolic processGO:19015753160.101
cellular ketone metabolic processGO:0042180510.099
purine ribonucleoside triphosphate metabolic processGO:00092051400.098
response to estradiolGO:00323551640.095
response to radiationGO:00093141370.095
cellular response to organic cyclic compoundGO:00714072020.092
programmed cell deathGO:00125013920.092
tissue developmentGO:00098882520.092
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.090
response to vitaminGO:00332731310.090
response to glucocorticoidGO:00513842230.090
organic cyclic compound catabolic processGO:19013611750.088
inflammatory responseGO:00069541500.088
reproductionGO:00000032450.088
aromatic amino acid family metabolic processGO:000907290.087
response to cytokineGO:00340972150.086
organonitrogen compound catabolic processGO:19015651790.085
epithelium developmentGO:0060429960.084
response to peptideGO:19016522920.083
response to nutrient levelsGO:00316673700.082
behaviorGO:00076102050.079
positive regulation of programmed cell deathGO:00430681570.079
response to metal ionGO:00100382530.079
response to lipopolysaccharideGO:00324961910.079
4 chlorobiphenyl metabolic processGO:001888010.078
lipid metabolic processGO:00066292830.077
organonitrogen compound biosynthetic processGO:19015661670.077
response to ketoneGO:19016541820.076
response to molecule of bacterial originGO:00022371940.075
response to inorganic substanceGO:00100353770.071
heterocycle catabolic processGO:00467001670.069
nucleobase containing small molecule metabolic processGO:00550863160.068
response to hypoxiaGO:00016662310.067
cellular hormone metabolic processGO:0034754490.066
alpha amino acid biosynthetic processGO:1901607230.066
estrogen catabolic processGO:000671110.065
phthalate metabolic processGO:001896380.064
purine containing compound metabolic processGO:00725212530.063
response to insecticideGO:0017085210.062
calcitriol biosynthetic process from calciolGO:003637820.062
organophosphate catabolic processGO:00464341480.061
response to dexamethasoneGO:0071548490.061
benzene containing compound metabolic processGO:0042537220.060
central nervous system developmentGO:00074173110.059
cellular response to nitrogen compoundGO:19016992100.059
dicarboxylic acid metabolic processGO:0043648420.058
carbohydrate derivative metabolic processGO:19011353460.058
biphenyl catabolic processGO:007098020.058
brain developmentGO:00074202470.056
organic hydroxy compound metabolic processGO:19016151150.056
terpenoid metabolic processGO:0006721370.056
reproductive processGO:00224143720.056
arachidonic acid metabolic processGO:0019369200.054
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.053
response to acid chemicalGO:00011012220.053
aromatic amino acid family catabolic processGO:000907470.053
ribonucleoside metabolic processGO:00091191740.052
organ morphogenesisGO:0009887750.051
cellular response to cytokine stimulusGO:00713451270.051
multi organism reproductive processGO:00447032620.051
response to external biotic stimulusGO:00432072210.050
response to woundingGO:00096112540.050
cofactor metabolic processGO:0051186950.050
regulation of apoptotic processGO:00429813350.050
ras protein signal transductionGO:0007265290.048
naphthalene metabolic processGO:001893120.048
cell growthGO:00160491040.048
regulation of immunoglobulin productionGO:000263740.048
pallium developmentGO:0021543420.046
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.046
isoprenoid metabolic processGO:0006720450.046
growthGO:00400071650.046
regulation of blood circulationGO:19035221100.045
alkaloid metabolic processGO:000982030.045
sensory perceptionGO:00076001010.045
reactive oxygen species metabolic processGO:0072593370.045
cellular response to xenobiotic stimulusGO:0071466190.044
agingGO:00075682410.044
nucleotide metabolic processGO:00091172790.044
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.043
4 nitrophenol metabolic processGO:001896010.043
jak stat cascadeGO:0007259260.043
response to ionizing radiationGO:0010212590.043
naphthalene containing compound metabolic processGO:009042020.042
hepaticobiliary system developmentGO:0061008900.041
response to extracellular stimulusGO:00099913800.040
purine ribonucleotide catabolic processGO:00091541360.040
positive regulation of jak stat cascadeGO:0046427190.039
telencephalon developmentGO:0021537620.038
carbohydrate derivative catabolic processGO:19011361470.038
small gtpase mediated signal transductionGO:0007264360.038
regulation of immune system processGO:00026821230.038
steroid biosynthetic processGO:0006694480.038
regulation of cellular component organizationGO:00511283680.037
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.036
cellular response to alcoholGO:0097306870.036
intracellular signal transductionGO:00355563140.036
regulation of defense responseGO:0031347680.035
epithelial cell differentiationGO:0030855710.035
alpha amino acid catabolic processGO:1901606200.035
regulation of immune response to tumor cellGO:000283730.035
blood circulationGO:00080151830.035
nucleobase containing compound catabolic processGO:00346551520.035
carboxylic acid biosynthetic processGO:0046394830.034
response to decreased oxygen levelsGO:00362932370.033
regulation of secretionGO:00510462240.033
circulatory system processGO:00030131830.033
cellular component movementGO:00069282480.033
cytosolic calcium ion homeostasisGO:00514801400.033
small molecule catabolic processGO:0044282590.033
regulation of programmed cell deathGO:00430673410.032
trichloroethylene metabolic processGO:001897910.032
neuron differentiationGO:00301823680.032
regulation of response to stressGO:00801341260.032
positive regulation of multicellular organismal processGO:00512403870.032
nucleoside phosphate catabolic processGO:19012921400.032
cellular amino acid biosynthetic processGO:0008652320.032
purine containing compound catabolic processGO:00725231380.031
regulation of cellular catabolic processGO:00313291010.031
positive regulation of apoptotic processGO:00430651540.031
hormone metabolic processGO:0042445690.031
cellular response to corticosteroid stimulusGO:0071384690.031
head developmentGO:00603222470.031
negative regulation of metabolic processGO:00098923310.030
b cell activation involved in immune responseGO:000231210.030
response to tumor cellGO:000234740.030
cellular nitrogen compound catabolic processGO:00442701630.030
regulation of intracellular signal transductionGO:19025312180.030
apoptotic processGO:00069153810.030
xenobiotic metabolic processGO:0006805190.030
phenylpropanoid catabolic processGO:004627130.029
regulation of cellular amino acid metabolic processGO:000652120.029
response to hydrogen peroxideGO:0042542890.028
negative regulation of rna biosynthetic processGO:19026791180.028
stress activated protein kinase signaling cascadeGO:0031098370.028
amine metabolic processGO:0009308380.028
long chain fatty acid metabolic processGO:0001676320.028
positive regulation of molecular functionGO:00440932300.028
coumarin catabolic processGO:004622630.028
fatty acid metabolic processGO:0006631990.028
cation homeostasisGO:00550801950.028
purine nucleotide catabolic processGO:00061951360.027
regulation of molecular functionGO:00650093980.027
glycosyl compound metabolic processGO:19016571820.027
androgen biosynthetic processGO:0006702100.027
smooth muscle cell proliferationGO:0048659770.026
innate immune responseGO:0045087350.026
regulation of multicellular organismal developmentGO:20000263760.026
gonad developmentGO:00084061040.026
nucleoside metabolic processGO:00091161790.026
response to cesium ionGO:001016420.026
limbic system developmentGO:0021761380.026
response to reactive oxygen speciesGO:00003021200.025
positive regulation of phosphorylationGO:00423271770.025
icosanoid metabolic processGO:0006690380.025
cell migrationGO:00164771970.025
cellular response to stressGO:00335542690.024
anatomical structure morphogenesisGO:00096532980.024
ribose phosphate metabolic processGO:00196932350.024
progesterone metabolic processGO:004244880.024
cellular response to external stimulusGO:00714961180.024
regulation of cellular ketone metabolic processGO:0010565270.024
regulation of cell developmentGO:00602842630.023
nucleoside triphosphate metabolic processGO:00091411440.023
developmental process involved in reproductionGO:00030061590.023
nucleotide catabolic processGO:00091661390.023
regulation of catalytic activityGO:00507903040.023
cellular response to mechanical stimulusGO:0071260480.023
positive regulation of nucleotide metabolic processGO:0045981910.023
regulation of system processGO:00440572080.023
cyclic nucleotide biosynthetic processGO:0009190630.023
negative regulation of macromolecule metabolic processGO:00106052600.023
positive regulation of phosphate metabolic processGO:00459372620.023
nucleoside phosphate metabolic processGO:00067532830.022
fatty acid derivative metabolic processGO:1901568380.022
immune responseGO:00069551040.022
vitamin d metabolic processGO:004235940.022
regulation of anatomical structure morphogenesisGO:00226031410.022
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressureGO:000199910.022
sex differentiationGO:00075481130.022
nitrogen cycle metabolic processGO:007194150.022
sterol metabolic processGO:0016125180.022
response to increased oxygen levelsGO:0036296450.022
cellular response to glucocorticoid stimulusGO:0071385680.022
cellular amine metabolic processGO:0044106380.022
sterol homeostasisGO:005509230.021
insecticide metabolic processGO:001714340.021
positive regulation of response to stimulusGO:00485842850.021
purine nucleotide metabolic processGO:00061632290.021
response to activityGO:0014823730.021
ribonucleotide catabolic processGO:00092611360.021
secondary alcohol metabolic processGO:190265220.021
regulation of hormone levelsGO:00108171870.021
lauric acid metabolic processGO:004825240.021
regulation of tube sizeGO:0035150890.021
positive regulation of biosynthetic processGO:00098913190.021
response to ethanolGO:00454711620.021
regulation of immune responseGO:0050776550.021
regulation of ion transportGO:00432692450.021
reactive nitrogen species metabolic processGO:200105710.021
c21 steroid hormone metabolic processGO:0008207140.021
acute inflammatory responseGO:0002526580.021
negative regulation of immune system processGO:0002683390.020
cellular response to growth factor stimulusGO:00713631620.020
immune system processGO:00023762040.020
regulation of endocytosisGO:0030100420.020
artery smooth muscle contractionGO:001482440.020
rhythmic processGO:00485111560.020
purine ribonucleoside metabolic processGO:00461281680.020
negative regulation of transportGO:00510511360.020
purine nucleoside metabolic processGO:00422781690.020
regulation of phosphorylationGO:00423252480.020
regulation of catabolic processGO:00098941130.019
sulfur compound metabolic processGO:0006790700.019
regulation of phosphorus metabolic processGO:00511743490.019
response to herbicideGO:0009635160.019
muscle tissue developmentGO:0060537580.019
regulation of rna biosynthetic processGO:20011413810.019
ribonucleotide metabolic processGO:00092592310.019
purine nucleoside catabolic processGO:00061521240.018
glucan metabolic processGO:0044042230.018
retinoid metabolic processGO:0001523240.018
membrane organizationGO:0061024940.018
immune response to tumor cellGO:000241830.018
glycogen metabolic processGO:0005977230.018
regulation of growthGO:00400081050.018
cellular lipid metabolic processGO:00442552080.018
negative regulation of gene expressionGO:00106291990.018
metal ion transportGO:00300012890.018
female pregnancyGO:00075651220.018
endocrine system developmentGO:0035270300.018
locomotionGO:00400112370.018
glycosyl compound catabolic processGO:19016581260.018
regulation of cellular amine metabolic processGO:003323880.018
protein transportGO:00150311320.017
ion homeostasisGO:00508012120.017
regulation of cell motilityGO:20001451310.017
regulation of blood pressureGO:0008217830.017
cellular amide metabolic processGO:0043603440.017
response to vitamin dGO:0033280340.017
muscle cell differentiationGO:0042692520.017
regulation of inflammatory responseGO:0050727480.017
unsaturated fatty acid metabolic processGO:0033559390.017
response to carbohydrateGO:00097431830.017
purine nucleoside triphosphate metabolic processGO:00091441410.017
neuron developmentGO:00486662860.017
fat soluble vitamin biosynthetic processGO:004236220.017
response to calcium ionGO:0051592590.017
behavioral response to nicotineGO:003509520.017
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.017
secretionGO:00469033070.017
localization of cellGO:00516742020.017
regulation of body fluid levelsGO:0050878900.017
macromolecule localizationGO:00330362520.017
multi multicellular organism processGO:00447061380.017
cytokine biosynthetic processGO:004208930.017
regulation of phosphate metabolic processGO:00192203490.017
sorbitol biosynthetic processGO:000606110.016
response to insulinGO:00328681330.016
organ regenerationGO:00311001010.016
hippocampus developmentGO:0021766300.016
homeostatic processGO:00425923310.016
multicellular organismal reproductive processGO:00486092330.016
regulation of neuron differentiationGO:00456642080.016
regulation of reactive oxygen species metabolic processGO:2000377260.016
response to ddtGO:004668010.016
response to mercury ionGO:0046689150.016
cellular glucan metabolic processGO:0006073230.016
rho protein signal transductionGO:0007266110.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.016
lipid catabolic processGO:0016042460.016
regulation of response to tumor cellGO:000283430.016
leukocyte cell cell adhesionGO:000715940.015
regulation of cell growthGO:0001558850.015
toxin catabolic processGO:000940710.015
response to peptide hormoneGO:00434342780.015
positive regulation of cellular amine metabolic processGO:003324030.015
development of primary female sexual characteristicsGO:0046545560.015
regulation of jak stat cascadeGO:0046425210.015
catecholamine biosynthetic processGO:004242390.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
response to monosaccharideGO:00342841590.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
positive regulation of hydrolase activityGO:0051345860.015
regulation of bile acid biosynthetic processGO:007085710.015
regulation of nucleotide metabolic processGO:00061401170.015
cellular sodium ion homeostasisGO:000688340.015
positive regulation of cell proliferationGO:00082842490.015
purine ribonucleotide metabolic processGO:00091502270.014
cell motilityGO:00488702020.014
cellular modified amino acid metabolic processGO:0006575610.014
bile acid biosynthetic processGO:000669930.014
positive regulation of protein metabolic processGO:00512471780.014
cellular response to ketoneGO:1901655510.014
regulation of cell proliferationGO:00421273590.014
catecholamine metabolic processGO:0006584190.014
regulation of signal transductionGO:00099663180.014
cellular amino acid catabolic processGO:0009063210.014
negative regulation of phosphorus metabolic processGO:0010563800.014
response to retinoic acidGO:0032526630.014
hormone secretionGO:00468791150.014
reproductive structure developmentGO:00486081280.014
cellular polysaccharide metabolic processGO:0044264230.014
negative regulation of cellular metabolic processGO:00313242810.014
regulation of response to external stimulusGO:00321011060.014
cellular homeostasisGO:00197252520.014
single organism reproductive processGO:00447022970.014
purine ribonucleoside catabolic processGO:00461301240.014
cellular response to insulin stimulusGO:0032869810.014
divalent metal ion transportGO:00708381320.014
multicellular organism reproductionGO:00325042330.014
regulation of serine type peptidase activityGO:190257110.013
regulation of membrane potentialGO:00423911100.013
positive regulation of intracellular signal transductionGO:19025331380.013
regulation of immunoglobulin secretionGO:005102310.013
gland developmentGO:00487321550.013
toxin metabolic processGO:000940490.013
response to alkaloidGO:00432791320.013
epoxygenase p450 pathwayGO:001937310.013
gtp metabolic processGO:0046039720.013
protein phosphorylationGO:00064683450.013
positive regulation of phosphorus metabolic processGO:00105622620.013
response to coldGO:0009409290.013
positive regulation of cellular amino acid metabolic processGO:004576410.013
endocrine processGO:0050886320.013
heart growthGO:0060419200.013
cellular response to acid chemicalGO:0071229750.013
cellular response to growth hormone stimulusGO:007137860.013
positive regulation of signal transductionGO:00099671750.013
positive regulation of purine nucleotide catabolic processGO:0033123530.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
neuron projection developmentGO:00311752730.013
response to vitamin aGO:0033189360.013
cholesterol homeostasisGO:004263230.013
response to gonadotropinGO:0034698340.013
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.013
regulation of protein modification processGO:00313991940.013
peptidyl amino acid modificationGO:00181931260.013
phenol containing compound metabolic processGO:0018958300.013
positive regulation of cell deathGO:00109421840.013
response to amino acidGO:0043200750.013
cyclic nucleotide metabolic processGO:0009187800.013
liver developmentGO:0001889900.013
cellular response to molecule of bacterial originGO:0071219560.012
response to toxic substanceGO:00096361330.012
nucleoside triphosphate catabolic processGO:00091431230.012
renin secretion into blood streamGO:000200110.012
reproductive system developmentGO:00614581280.012
response to temperature stimulusGO:0009266940.012
response to fatty acidGO:0070542650.012
positive regulation of immunoglobulin mediated immune responseGO:000289120.012
positive regulation of isotype switchingGO:004583010.012
multicellular organismal homeostasisGO:0048871490.012
regulation of homeostatic processGO:00328441010.012
blood coagulationGO:0007596260.012
sterol catabolic processGO:001612710.012
positive regulation of immunoglobulin productionGO:000263940.012
parturitionGO:0007567100.012
single organism carbohydrate metabolic processGO:00447231180.012
reactive oxygen species biosynthetic processGO:190340980.012
c21 steroid hormone biosynthetic processGO:0006700100.012
regulation of isotype switchingGO:004519110.012
renin angiotensin regulation of aldosterone productionGO:000201830.012
vitamin biosynthetic processGO:000911030.012
positive regulation of epithelial cell proliferationGO:0050679320.012
sensory perception of bitter tasteGO:005091340.012
negative regulation of innate immune responseGO:004582440.012
exogenous drug catabolic processGO:004273810.012
regulation of transferase activityGO:00513381230.012
erk1 and erk2 cascadeGO:0070371480.012
cellular response to abiotic stimulusGO:0071214850.012
regulation of protein metabolic processGO:00512462890.011
negative regulation of catalytic activityGO:00430861030.011
vitamin d3 metabolic processGO:007064020.011
diterpenoid metabolic processGO:0016101330.011
positive regulation of renin secretion into blood streamGO:190013510.011
cellular metal ion homeostasisGO:00068751720.011
muscle cell proliferationGO:0033002840.011
stress activated mapk cascadeGO:0051403350.011
protein complex biogenesisGO:00702712630.011
regulation of cellular component movementGO:00512701500.011
urea metabolic processGO:001962750.011
defense response to gram negative bacteriumGO:005082930.011
developmental growthGO:00485891000.011
circadian sleep wake cycleGO:0042745230.011
vascular process in circulatory systemGO:0003018960.011
urogenital system developmentGO:0001655780.011
circadian rhythmGO:0007623880.011
secondary metabolite catabolic processGO:009048710.011
tube developmentGO:0035295890.011
taxisGO:0042330670.011
protein localizationGO:00081041910.011
positive regulation of homeostatic processGO:0032846490.011
monocarboxylic acid biosynthetic processGO:0072330480.011
hormone catabolic processGO:004244720.011
negative regulation of cell proliferationGO:00082851190.011
regulation of purine nucleotide catabolic processGO:0033121650.011
development of primary sexual characteristicsGO:00451371070.011
cell chemotaxisGO:0060326310.011
positive regulation of signalingGO:00230562700.011
response to mechanical stimulusGO:00096121340.011
cellular response to hexose stimulusGO:0071331650.011
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.011
regulation of systemic arterial blood pressureGO:0003073300.011
polysaccharide metabolic processGO:0005976250.011
regulation of vesicle mediated transportGO:0060627810.011
lymphocyte activation involved in immune responseGO:000228530.011
gtp catabolic processGO:0006184710.011
regulation of cellular localizationGO:00603412630.011
response to organophosphorusGO:00466831020.011
negative regulation of molecular functionGO:00440921330.011
tonic smooth muscle contractionGO:001482040.010
cellular response to lipopolysaccharideGO:0071222550.010
blood vessel developmentGO:0001568690.010
regulation of cell differentiationGO:00455953200.010
b cell mediated immunityGO:001972440.010
guanosine containing compound metabolic processGO:1901068740.010
regulation of developmental growthGO:0048638450.010
regulation of immunoglobulin mediated immune responseGO:000288920.010
circadian regulation of gene expressionGO:003292230.010
indolalkylamine metabolic processGO:000658650.010
protein oligomerizationGO:00512591910.010
cell communication involved in cardiac conductionGO:008606520.010
serine phosphorylation of stat proteinGO:004250120.010
cell adhesionGO:00071551100.010
tumor necrosis factor mediated signaling pathwayGO:003320940.010
response to testosteroneGO:0033574550.010
positive regulation of cellular catabolic processGO:0031331710.010
positive regulation of cell communicationGO:00106472710.010
steroid catabolic processGO:000670650.010

Cyp2c12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.051
inherited metabolic disorderDOID:65500.049
disease of anatomical entityDOID:700.025
nervous system diseaseDOID:86300.025
cardiovascular system diseaseDOID:128700.022
vascular diseaseDOID:17800.022
hypertensionDOID:1076300.019
essential hypertensionDOID:1082500.019
artery diseaseDOID:005082800.019