Rattus norvegicus

27 known processes

Lig4

ligase IV, DNA, ATP-dependent

Lig4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic acid metabolic processGO:00060822920.043
cellular amino acid metabolic processGO:00065201070.035
cation transportGO:00068123820.034
positive regulation of nitrogen compound metabolic processGO:00511733340.034
rna biosynthetic processGO:00327743800.034
homeostatic processGO:00425923310.034
ion transmembrane transportGO:00342203650.033
cellular response to oxygen containing compoundGO:19017013860.033
oxoacid metabolic processGO:00434362900.032
carbohydrate derivative metabolic processGO:19011353460.032
regulation of transcription dna templatedGO:00063553740.032
carboxylic acid metabolic processGO:00197522890.032
cellular component movementGO:00069282480.031
transmembrane transportGO:00550854120.031
rna metabolic processGO:00160704060.031
reproductive processGO:00224143720.030
protein phosphorylationGO:00064683450.030
amine metabolic processGO:0009308380.029
nucleic acid templated transcriptionGO:00976593790.029
intracellular signal transductionGO:00355563140.029
cellular amine metabolic processGO:0044106380.029
regulation of cellular amino acid metabolic processGO:000652120.029
programmed cell deathGO:00125013920.029
regulation of apoptotic processGO:00429813350.029
regulation of cellular amine metabolic processGO:003323880.028
regulation of phosphorylationGO:00423252480.028
nucleobase containing small molecule metabolic processGO:00550863160.028
regulation of phosphate metabolic processGO:00192203490.028
regulation of programmed cell deathGO:00430673410.028
macromolecular complex subunit organizationGO:00439333390.028
regulation of molecular functionGO:00650093980.027
response to nutrient levelsGO:00316673700.027
response to inorganic substanceGO:00100353770.027
regulation of signal transductionGO:00099663180.027
cellular component biogenesisGO:00440853680.026
cellular homeostasisGO:00197252520.026
regulation of nucleic acid templated transcriptionGO:19035063800.026
cellular ketone metabolic processGO:0042180510.026
catabolic processGO:00090563510.026
metal ion transportGO:00300012890.026
regulation of cellular ketone metabolic processGO:0010565270.025
regulation of phosphorus metabolic processGO:00511743490.025
ion homeostasisGO:00508012120.025
apoptotic processGO:00069153810.025
negative regulation of metabolic processGO:00098923310.025
nucleotide metabolic processGO:00091172790.025
regulation of rna biosynthetic processGO:20011413810.025
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
cellular catabolic processGO:00442482950.025
transcription dna templatedGO:00063513770.025
organophosphate metabolic processGO:00196373700.025
response to extracellular stimulusGO:00099913800.024
organelle organizationGO:00069962660.024
organic substance catabolic processGO:19015753160.024
cellular chemical homeostasisGO:00550822470.024
chemical homeostasisGO:00488782920.024
regulation of cell differentiationGO:00455953200.024
regulation of catalytic activityGO:00507903040.024
regulation of system processGO:00440572080.024
anatomical structure morphogenesisGO:00096532980.023
nucleoside phosphate metabolic processGO:00067532830.023
response to decreased oxygen levelsGO:00362932370.023
multicellular organismal reproductive processGO:00486092330.023
cellular component assemblyGO:00226073600.023
positive regulation of cell communicationGO:00106472710.022
positive regulation of biosynthetic processGO:00098913190.022
cellular response to endogenous stimulusGO:00714953770.022
macromolecular complex assemblyGO:00650032730.022
central nervous system developmentGO:00074173110.022
secretionGO:00469033070.022
regulation of rna metabolic processGO:00512523910.022
single organism catabolic processGO:00447122830.022
purine containing compound metabolic processGO:00725212530.022
metal ion homeostasisGO:00550651860.021
regulation of cellular component organizationGO:00511283680.021
regulation of multicellular organismal developmentGO:20000263760.021
brain developmentGO:00074202470.021
response to oxygen levelsGO:00704822650.021
purine ribonucleotide metabolic processGO:00091502270.021
cation homeostasisGO:00550801950.021
ribose phosphate metabolic processGO:00196932350.021
cellular cation homeostasisGO:00300031800.021
positive regulation of cell differentiationGO:00455972170.021
response to hypoxiaGO:00016662310.020
neuron differentiationGO:00301823680.020
positive regulation of multicellular organismal processGO:00512403870.020
cell cell signalingGO:00072673350.020
positive regulation of signalingGO:00230562700.020
circulatory system processGO:00030131830.020
blood circulationGO:00080151830.020
agingGO:00075682410.020
regulation of intracellular signal transductionGO:19025312180.020
glycosyl compound metabolic processGO:19016571820.020
positive regulation of phosphate metabolic processGO:00459372620.020
positive regulation of cellular amine metabolic processGO:003324030.020
regulation of cellular localizationGO:00603412630.020
head developmentGO:00603222470.020
single organism reproductive processGO:00447022970.019
protein complex biogenesisGO:00702712630.019
protein complex subunit organizationGO:00718223020.019
regulation of cell proliferationGO:00421273590.019
positive regulation of developmental processGO:00510942830.019
reproductionGO:00000032450.019
regulation of nervous system developmentGO:00519602640.019
cell projection organizationGO:00300303020.019
ribonucleotide metabolic processGO:00092592310.019
cellular ion homeostasisGO:00068731840.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
positive regulation of cellular biosynthetic processGO:00313282950.019
lipid metabolic processGO:00066292830.019
positive regulation of cell proliferationGO:00082842490.019
neuron developmentGO:00486662860.019
multi organism reproductive processGO:00447032620.019
single organism intracellular transportGO:19025821660.018
negative regulation of macromolecule metabolic processGO:00106052600.018
positive regulation of phosphorylationGO:00423271770.018
transcription from rna polymerase ii promoterGO:00063662520.018
divalent inorganic cation homeostasisGO:00725071650.018
positive regulation of phosphorus metabolic processGO:00105622620.018
positive regulation of response to stimulusGO:00485842850.018
regulation of neurogenesisGO:00507672470.018
macromolecule localizationGO:00330362520.018
single organism biosynthetic processGO:00447113420.018
purine nucleotide metabolic processGO:00061632290.018
mapk cascadeGO:00001651400.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
small gtpase mediated signal transductionGO:0007264360.018
regulation of cell developmentGO:00602842630.018
cellular response to stressGO:00335542690.018
multicellular organism reproductionGO:00325042330.018
protein complex assemblyGO:00064612630.018
protein localizationGO:00081041910.017
cation transmembrane transportGO:00986552630.017
tissue developmentGO:00098882520.017
ribonucleoside metabolic processGO:00091191740.017
negative regulation of cellular metabolic processGO:00313242810.017
intracellular transportGO:00469071850.017
oxidation reduction processGO:00551143040.017
neurological system processGO:00508772190.017
negative regulation of programmed cell deathGO:00430691830.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
inorganic ion transmembrane transportGO:00986602290.017
synaptic transmissionGO:00072682350.017
calcium ion homeostasisGO:00550741620.017
secretion by cellGO:00329402480.017
regulation of protein phosphorylationGO:00019321830.017
cellular metal ion homeostasisGO:00068751720.017
negative regulation of cell deathGO:00605482290.017
cellular divalent inorganic cation homeostasisGO:00725031620.017
nucleoside metabolic processGO:00091161790.016
locomotionGO:00400112370.016
cellular calcium ion homeostasisGO:00068741600.016
positive regulation of gene expressionGO:00106282440.016
positive regulation of molecular functionGO:00440932300.016
single organism organelle organizationGO:19025891800.016
protein transportGO:00150311320.016
response to ketoneGO:19016541820.016
muscle system processGO:00030121150.016
positive regulation of rna metabolic processGO:00512542030.016
response to metal ionGO:00100382530.016
heterocycle catabolic processGO:00467001670.016
response to peptide hormoneGO:00434342780.016
ras protein signal transductionGO:0007265290.016
regulation of protein modification processGO:00313991940.016
divalent inorganic cation transportGO:00725111340.016
response to growth factorGO:00708481890.016
purine nucleoside catabolic processGO:00061521240.016
regulation of neuron differentiationGO:00456642080.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
response to nutrientGO:00075842480.015
response to acid chemicalGO:00011012220.015
g protein coupled receptor signaling pathwayGO:00071862420.015
protein oligomerizationGO:00512591910.015
purine nucleoside metabolic processGO:00422781690.015
establishment of protein localizationGO:00451841410.015
negative regulation of response to stimulusGO:00485851550.015
anterior posterior pattern specificationGO:000995210.015
regulation of cellular protein metabolic processGO:00322682670.015
nucleoside phosphate catabolic processGO:19012921400.015
nitrogen compound transportGO:00717052290.015
neuron projection developmentGO:00311752730.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
regulation of protein metabolic processGO:00512462890.015
organic cyclic compound catabolic processGO:19013611750.015
positive regulation of programmed cell deathGO:00430681570.015
vesicle mediated transportGO:00161921810.015
cellular response to growth factor stimulusGO:00713631620.015
negative regulation of apoptotic processGO:00430661810.015
positive regulation of protein modification processGO:00314011420.014
peptidyl amino acid modificationGO:00181931260.014
localization of cellGO:00516742020.014
heart morphogenesisGO:000300730.014
proteolysisGO:00065081750.014
regulation of membrane potentialGO:00423911100.014
signal transduction by phosphorylationGO:00230141440.014
defense responseGO:00069521940.014
cellular lipid metabolic processGO:00442552080.014
cell motilityGO:00488702020.014
gastrulationGO:000736920.014
positive regulation of cellular component organizationGO:00511302000.014
response to toxic substanceGO:00096361330.014
positive regulation of cell developmentGO:00107201760.014
cellular nitrogen compound catabolic processGO:00442701630.014
response to peptideGO:19016522920.014
response to oxidative stressGO:00069791860.014
purine ribonucleotide catabolic processGO:00091541360.014
regulation of mapk cascadeGO:00434081160.014
response to corticosteroidGO:00319602350.014
regulation of neuron projection developmentGO:00109751610.014
positive regulation of rna biosynthetic processGO:19026801970.014
positive regulation of transcription dna templatedGO:00458931970.014
negative regulation of transportGO:00510511360.014
regulation of secretionGO:00510462240.014
purine ribonucleoside metabolic processGO:00461281680.014
negative regulation of innate immune responseGO:004582440.014
negative regulation of multicellular organismal processGO:00512412030.014
gland developmentGO:00487321550.014
immune system processGO:00023762040.014
anion transportGO:00068201780.014
negative regulation of biosynthetic processGO:00098901680.014
positive regulation of catalytic activityGO:00430851840.014
glycosyl compound catabolic processGO:19016581260.014
cellular response to nitrogen compoundGO:19016992100.014
nucleobase containing compound catabolic processGO:00346551520.014
nucleotide catabolic processGO:00091661390.014
negative regulation of signalingGO:00230571570.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
response to estrogenGO:00436272320.014
organonitrogen compound catabolic processGO:19015651790.014
positive regulation of protein phosphorylationGO:00019341350.014
reactive oxygen species metabolic processGO:0072593370.014
monovalent inorganic cation transportGO:00156721720.014
response to other organismGO:00517072200.014
carbohydrate derivative catabolic processGO:19011361470.013
response to glucocorticoidGO:00513842230.013
purine nucleotide catabolic processGO:00061951360.013
positive regulation of signal transductionGO:00099671750.013
regulation of blood circulationGO:19035221100.013
cell migrationGO:00164771970.013
divalent metal ion transportGO:00708381320.013
negative regulation of gene expressionGO:00106291990.013
aromatic compound catabolic processGO:00194391680.013
positive regulation of cell deathGO:00109421840.013
inorganic cation transmembrane transportGO:00986622020.013
response to carbohydrateGO:00097431830.013
regulation of cell projection organizationGO:00313441750.013
organophosphate catabolic processGO:00464341480.013
cytosolic calcium ion homeostasisGO:00514801400.013
single organism carbohydrate metabolic processGO:00447231180.013
ribonucleotide catabolic processGO:00092611360.013
regulation of secretion by cellGO:19035302080.013
cytoplasmic transportGO:00164821150.013
regulation of synaptic transmissionGO:00508041410.013
regulation of hormone levelsGO:00108171870.013
regulation of anatomical structure sizeGO:00900661350.013
positive regulation of neurogenesisGO:00507691650.013
sexual reproductionGO:00199531480.013
eye morphogenesisGO:004859240.013
behaviorGO:00076102050.013
cellular response to hormone stimulusGO:00328702470.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
response to external biotic stimulusGO:00432072210.013
positive regulation of nervous system developmentGO:00519621780.013
ribonucleoside catabolic processGO:00424541260.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
negative regulation of cell communicationGO:00106481580.013
cellular macromolecule localizationGO:00707271220.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
response to biotic stimulusGO:00096072260.013
ribonucleoside triphosphate metabolic processGO:00091991410.013
positive regulation of intracellular signal transductionGO:19025331380.012
carbohydrate derivative biosynthetic processGO:19011371240.012
axis specificationGO:000979840.012
cellular component morphogenesisGO:00329891550.012
nucleoside catabolic processGO:00091641260.012
positive regulation of protein metabolic processGO:00512471780.012
positive regulation of cellular protein metabolic processGO:00322701670.012
positive regulation of transportGO:00510502450.012
regulation of homeostatic processGO:00328441010.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
nucleoside triphosphate metabolic processGO:00091411440.012
regulation of cell motilityGO:20001451310.012
regulation of transferase activityGO:00513381230.012
regulation of cell migrationGO:00303341280.012
salivary gland developmentGO:000743130.012
regulation of canonical wnt signaling pathwayGO:006082840.012
cellular response to organonitrogen compoundGO:00714171970.012
cellular protein localizationGO:00346131220.012
organonitrogen compound biosynthetic processGO:19015661670.012
cellular response to lipidGO:00713962010.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
regulation of catabolic processGO:00098941130.012
calcium ion transportGO:00068161310.012
chromosome segregationGO:000705920.012
purine ribonucleoside catabolic processGO:00461301240.012
regulation of locomotionGO:00400121480.012
purine containing compound catabolic processGO:00725231380.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
inflammatory responseGO:00069541500.011
sequestering of metal ionGO:005123890.011
positive regulation of neuron differentiationGO:00456661260.011
growthGO:00400071650.011
response to ethanolGO:00454711620.011
action potentialGO:0001508540.011
regenerationGO:00310991630.011
maintenance of locationGO:0051235170.011
regulation of ion transportGO:00432692450.011
nucleoside triphosphate catabolic processGO:00091431230.011
multi multicellular organism processGO:00447061380.011
regulation of cellular component movementGO:00512701500.011
embryonic pattern specificationGO:000988010.011
rhythmic processGO:00485111560.011
cell morphogenesisGO:00009021420.011
response to bacteriumGO:00096172000.011
response to glucoseGO:00097491360.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
regulation of purine nucleotide metabolic processGO:19005421150.011
leukocyte cell cell adhesionGO:000715940.011
rho protein signal transductionGO:0007266110.011
lipid storageGO:001991510.011
gamete generationGO:00072761240.011
single organism membrane organizationGO:0044802740.011
cellular response to organic cyclic compoundGO:00714072020.011
response to lipopolysaccharideGO:00324961910.011
reactive nitrogen species metabolic processGO:200105710.011
negative regulation of rna metabolic processGO:00512531230.011
positive regulation of nucleotide metabolic processGO:0045981910.011
negative regulation of natural killer cell mediated immunityGO:000271640.011
actin filament based processGO:0030029860.011
male gamete generationGO:0048232990.011
neuron deathGO:00709971270.011
spermatogenesisGO:0007283990.011
response to molecule of bacterial originGO:00022371940.011
signal releaseGO:00230611450.011
sensory perceptionGO:00076001010.011
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.010
response to insulinGO:00328681330.010
response to monosaccharideGO:00342841590.010
regulation of kinase activityGO:00435491170.010
regulation of muscle system processGO:0090257790.010
response to transition metal nanoparticleGO:19902671220.010
anion transmembrane transportGO:0098656770.010
positive regulation of apoptotic processGO:00430651540.010
developmental process involved in reproductionGO:00030061590.010
bmp signaling pathwayGO:003050940.010
regulation of mrna splicing via spliceosomeGO:004802430.010
protein homooligomerizationGO:0051260910.010
regulation of immune system processGO:00026821230.010
response to hexoseGO:00097461440.010
female pregnancyGO:00075651220.010
response to reactive oxygen speciesGO:00003021200.010
regulation of neuron deathGO:19012141150.010
reproductive structure developmentGO:00486081280.010
regulation of metal ion transportGO:00109591180.010

Lig4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
disease of metabolismDOID:001466700.018
musculoskeletal system diseaseDOID:1700.015
inherited metabolic disorderDOID:65500.013
central nervous system diseaseDOID:33100.013
sensory system diseaseDOID:005015500.011
muscular diseaseDOID:008000000.010
muscle tissue diseaseDOID:6600.010