Rattus norvegicus

29 known processes

Lig3

ligase III, DNA, ATP-dependent

Lig3 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of anatomical structure morphogenesisGO:00226031410.384
positive regulation of macromolecule biosynthetic processGO:00105572470.350
regulation of transcription dna templatedGO:00063553740.350
positive regulation of rna metabolic processGO:00512542030.341
tissue developmentGO:00098882520.340
regulation of cellular protein metabolic processGO:00322682670.297
regulation of cellular component organizationGO:00511283680.291
negative regulation of metabolic processGO:00098923310.281
positive regulation of transcription dna templatedGO:00458931970.279
cellular component assemblyGO:00226073600.277
reproductive structure developmentGO:00486081280.271
macromolecular complex assemblyGO:00650032730.269
secretionGO:00469033070.262
cellular response to hormone stimulusGO:00328702470.260
rna metabolic processGO:00160704060.252
cellular response to endogenous stimulusGO:00714953770.248
positive regulation of transportGO:00510502450.248
regulation of nucleic acid templated transcriptionGO:19035063800.236
positive regulation of multicellular organismal processGO:00512403870.233
protein complex assemblyGO:00064612630.232
cellular response to peptide hormone stimulusGO:00713751200.231
macromolecular complex subunit organizationGO:00439333390.225
response to monosaccharideGO:00342841590.222
development of primary sexual characteristicsGO:00451371070.215
positive regulation of cellular biosynthetic processGO:00313282950.214
regulation of multicellular organismal developmentGO:20000263760.213
macromolecule localizationGO:00330362520.208
intracellular signal transductionGO:00355563140.204
cellular component biogenesisGO:00440853680.202
regulation of transcription from rna polymerase ii promoterGO:00063572340.202
cellular response to peptideGO:19016531330.202
regulation of protein metabolic processGO:00512462890.198
nucleic acid templated transcriptionGO:00976593790.193
protein complex biogenesisGO:00702712630.192
gonad developmentGO:00084061040.182
transcription dna templatedGO:00063513770.179
developmental process involved in reproductionGO:00030061590.179
response to hypoxiaGO:00016662310.175
positive regulation of developmental processGO:00510942830.174
cell morphogenesisGO:00009021420.172
positive regulation of biosynthetic processGO:00098913190.172
positive regulation of nitrogen compound metabolic processGO:00511733340.170
regulation of rna biosynthetic processGO:20011413810.166
cellular response to stressGO:00335542690.164
positive regulation of gene expressionGO:00106282440.158
apoptotic processGO:00069153810.157
regulation of programmed cell deathGO:00430673410.154
regulation of apoptotic processGO:00429813350.148
single organism reproductive processGO:00447022970.147
transcription from rna polymerase ii promoterGO:00063662520.143
positive regulation of rna biosynthetic processGO:19026801970.142
reproductive processGO:00224143720.142
rhythmic processGO:00485111560.139
cell differentiation involved in kidney developmentGO:006100540.138
response to hexoseGO:00097461440.138
positive regulation of cell motilityGO:2000147970.137
positive regulation of apoptotic processGO:00430651540.137
programmed cell deathGO:00125013920.136
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.135
anatomical structure morphogenesisGO:00096532980.134
cellular homeostasisGO:00197252520.133
reproductive system developmentGO:00614581280.131
response to other organismGO:00517072200.131
positive regulation of nucleic acid templated transcriptionGO:19035081970.128
response to peptide hormoneGO:00434342780.127
regulation of rna metabolic processGO:00512523910.126
organ morphogenesisGO:0009887750.124
multi organism reproductive processGO:00447032620.121
positive regulation of nucleobase containing compound metabolic processGO:00459353190.119
cell migrationGO:00164771970.119
negative regulation of cellular metabolic processGO:00313242810.118
positive regulation of cellular component organizationGO:00511302000.116
positive regulation of cell differentiationGO:00455972170.115
response to decreased oxygen levelsGO:00362932370.115
cellular response to growth factor stimulusGO:00713631620.112
cellular component movementGO:00069282480.112
multicellular organism reproductionGO:00325042330.111
sex differentiationGO:00075481130.111
response to glucoseGO:00097491360.110
cellular response to oxygen containing compoundGO:19017013860.109
female gonad developmentGO:0008585530.109
regulation of cellular localizationGO:00603412630.108
positive regulation of interleukin 1 beta secretionGO:005071830.107
cellular response to organonitrogen compoundGO:00714171970.106
positive regulation of response to stimulusGO:00485842850.105
negative regulation of macromolecule metabolic processGO:00106052600.105
single organism behaviorGO:00447081300.104
positive regulation of phosphorus metabolic processGO:00105622620.103
protein phosphorylationGO:00064683450.101
regulation of response to stressGO:00801341260.101
response to biotic stimulusGO:00096072260.101
cellular response to insulin stimulusGO:0032869810.100
response to extracellular stimulusGO:00099913800.100
protein oligomerizationGO:00512591910.098
regulation of cell differentiationGO:00455953200.097
response to growth factorGO:00708481890.097
cellular response to nitrogen compoundGO:19016992100.096
response to lipopolysaccharideGO:00324961910.096
learning or memoryGO:0007611900.096
response to external biotic stimulusGO:00432072210.095
enzyme linked receptor protein signaling pathwayGO:00071671160.093
development of primary female sexual characteristicsGO:0046545560.092
epithelium developmentGO:0060429960.092
negative regulation of cell deathGO:00605482290.092
protein autophosphorylationGO:0046777660.091
regulation of cellular ketone metabolic processGO:0010565270.090
cellular response to organic cyclic compoundGO:00714072020.089
response to oxygen levelsGO:00704822650.088
single organism organelle organizationGO:19025891800.088
neuron developmentGO:00486662860.088
regulation of secretionGO:00510462240.088
protein heterooligomerizationGO:0051291890.088
regulation of nervous system developmentGO:00519602640.087
multicellular organismal reproductive processGO:00486092330.087
response to toxic substanceGO:00096361330.087
negative regulation of gene expressionGO:00106291990.087
behaviorGO:00076102050.085
regulation of cell developmentGO:00602842630.084
gland developmentGO:00487321550.084
regulation of cellular amino acid metabolic processGO:000652120.084
tissue morphogenesisGO:0048729220.082
regulation of synaptic growth at neuromuscular junctionGO:000858210.080
ovulation cycleGO:0042698670.079
single organism biosynthetic processGO:00447113420.079
cellular chemical homeostasisGO:00550822470.079
regulation of molecular functionGO:00650093980.079
cell cell signalingGO:00072673350.079
neuron differentiationGO:00301823680.077
positive regulation of phosphate metabolic processGO:00459372620.077
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.077
response to carbohydrateGO:00097431830.076
regulation of signal transductionGO:00099663180.076
response to insulinGO:00328681330.075
cellular catabolic processGO:00442482950.075
response to bacteriumGO:00096172000.075
synaptic growth at neuromuscular junctionGO:005112410.074
positive regulation of catalytic activityGO:00430851840.074
response to nutrient levelsGO:00316673700.074
protein transportGO:00150311320.074
oxoacid metabolic processGO:00434362900.074
positive regulation of cell developmentGO:00107201760.073
cell projection organizationGO:00300303020.072
positive regulation of signalingGO:00230562700.071
central nervous system developmentGO:00074173110.071
reproductionGO:00000032450.070
positive regulation of cellular protein metabolic processGO:00322701670.070
positive regulation of programmed cell deathGO:00430681570.069
protein localizationGO:00081041910.069
innate immune responseGO:0045087350.068
locomotionGO:00400112370.068
regulation of neuron differentiationGO:00456642080.068
immune responseGO:00069551040.067
muscle structure developmentGO:0061061870.066
response to heatGO:0009408600.066
peptidyl amino acid modificationGO:00181931260.066
cellular amino acid metabolic processGO:00065201070.065
regulation of protein phosphorylationGO:00019321830.065
cellular component morphogenesisGO:00329891550.064
positive regulation of retinal cell programmed cell deathGO:004667010.064
response to woundingGO:00096112540.064
protein complex subunit organizationGO:00718223020.063
carboxylic acid metabolic processGO:00197522890.063
negative regulation of biosynthetic processGO:00098901680.063
morphogenesis of an epitheliumGO:0002009200.063
head developmentGO:00603222470.063
regulation of cell morphogenesis involved in differentiationGO:0010769720.063
positive regulation of signal transductionGO:00099671750.063
positive regulation of intracellular signal transductionGO:19025331380.062
negative regulation of programmed cell deathGO:00430691830.062
cellular ketone metabolic processGO:0042180510.060
rna biosynthetic processGO:00327743800.060
response to inorganic substanceGO:00100353770.060
agingGO:00075682410.059
neurological system processGO:00508772190.059
branching morphogenesis of an epithelial tubeGO:0048754140.059
growthGO:00400071650.058
single organism intracellular transportGO:19025821660.058
protein maturationGO:0051604680.058
positive regulation of cellular amino acid metabolic processGO:004576410.057
negative regulation of developmental processGO:00510931250.056
positive regulation of cell deathGO:00109421840.056
organelle organizationGO:00069962660.056
negative regulation of cell differentiationGO:0045596990.055
lipid transportGO:0006869610.055
regulation of phosphorylationGO:00423252480.055
regulation of protein modification processGO:00313991940.054
immune system processGO:00023762040.054
cellular amine metabolic processGO:0044106380.053
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.053
response to temperature stimulusGO:0009266940.053
homeostatic processGO:00425923310.052
brain developmentGO:00074202470.052
cellular amide metabolic processGO:0043603440.052
negative regulation of macromolecule biosynthetic processGO:00105581480.052
multicellular organism growthGO:003526410.052
positive regulation of phosphorylationGO:00423271770.052
protein processingGO:0016485680.050
eye morphogenesisGO:004859240.050
cytokine productionGO:0001816610.050
positive regulation of molecular functionGO:00440932300.050
regulation of cellular amine metabolic processGO:003323880.050
positive regulation of neurogenesisGO:00507691650.049
regulation of phosphorus metabolic processGO:00511743490.049
positive regulation of immune system processGO:0002684900.049
cell cycleGO:00070491010.048
skeletal muscle tissue developmentGO:0007519310.048
proteolysisGO:00065081750.047
female sex differentiationGO:0046660590.047
negative regulation of rna biosynthetic processGO:19026791180.047
defense responseGO:00069521940.047
lipid biosynthetic processGO:00086101280.047
response to metal ionGO:00100382530.046
ovulation cycle processGO:0022602500.046
regulation of interleukin 1 beta secretionGO:005070630.046
cellular protein localizationGO:00346131220.046
single organism cellular localizationGO:19025801020.046
cell morphogenesis involved in neuron differentiationGO:00486671060.046
signal transduction by phosphorylationGO:00230141440.045
positive regulation of defense responseGO:0031349370.045
regulation of phosphate metabolic processGO:00192203490.045
positive regulation of nervous system developmentGO:00519621780.045
positive regulation of response to external stimulusGO:0032103510.044
organic substance catabolic processGO:19015753160.044
negative regulation of protein metabolic processGO:00512481140.044
negative regulation of multicellular organismal processGO:00512412030.044
regulation of cell morphogenesisGO:0022604770.044
positive regulation of protein phosphorylationGO:00019341350.044
embryo developmentGO:0009790490.043
response to ethanolGO:00454711620.043
apoptotic signaling pathwayGO:0097190270.043
transmembrane transportGO:00550854120.043
embryonic pattern specificationGO:000988010.043
amine metabolic processGO:0009308380.042
negative regulation of apoptotic processGO:00430661810.042
positive regulation of protein metabolic processGO:00512471780.042
localization of cellGO:00516742020.042
monocarboxylic acid transportGO:0015718520.041
establishment of protein localization to organelleGO:0072594440.041
catabolic processGO:00090563510.040
regulation of circadian sleep wake cycle sleepGO:0045187180.040
dendrite developmentGO:0016358720.040
response to peptideGO:19016522920.040
regulation of immune responseGO:0050776550.040
cation homeostasisGO:00550801950.039
nucleotide metabolic processGO:00091172790.039
vasculogenesisGO:000157030.039
negative regulation of cellular protein metabolic processGO:00322691060.039
positive regulation of cellular component movementGO:00512721020.038
urogenital system developmentGO:0001655780.038
response to glucocorticoidGO:00513842230.038
developmental growthGO:00485891000.037
cell morphogenesis involved in differentiationGO:00009041190.037
anion transportGO:00068201780.037
chemical homeostasisGO:00488782920.037
response to reactive oxygen speciesGO:00003021200.037
regulation of growthGO:00400081050.036
ion homeostasisGO:00508012120.036
ion transmembrane transportGO:00342203650.036
anterior posterior pattern specificationGO:000995210.036
intracellular transportGO:00469071850.036
lipid localizationGO:0010876620.036
anatomical structure formation involved in morphogenesisGO:0048646830.036
carboxylic acid transportGO:00469421150.035
protein targetingGO:0006605610.035
protein import into nucleusGO:0006606350.035
digestive system developmentGO:0055123410.035
negative regulation of response to stimulusGO:00485851550.034
regulation of canonical wnt signaling pathwayGO:006082840.034
stem cell maintenanceGO:001982760.034
regulation of protein transportGO:0051223680.034
gamete generationGO:00072761240.034
mapk cascadeGO:00001651400.034
negative regulation of cellular biosynthetic processGO:00313271610.034
axis specificationGO:000979840.034
cellular cation homeostasisGO:00300031800.033
regulation of catalytic activityGO:00507903040.033
synapse organizationGO:0050808460.033
muscle organ developmentGO:0007517500.033
cation transportGO:00068123820.032
regulation of cell proliferationGO:00421273590.032
cellular ion homeostasisGO:00068731840.032
positive regulation of triglyceride biosynthetic processGO:001086740.031
cell motilityGO:00488702020.031
regulation of mapk cascadeGO:00434081160.031
mesoderm developmentGO:000749820.031
regulation of behaviorGO:0050795610.030
negative regulation of transcription dna templatedGO:00458921160.030
cellular lipid metabolic processGO:00442552080.030
positive regulation of cell proliferationGO:00082842490.030
response to mechanical stimulusGO:00096121340.030
positive regulation of cell communicationGO:00106472710.030
organic acid metabolic processGO:00060822920.030
single organism catabolic processGO:00447122830.030
protein homooligomerizationGO:0051260910.030
sensory organ developmentGO:0007423740.029
regulation of circadian sleep wake cycleGO:0042749180.029
kidney developmentGO:0001822670.029
positive regulation of cellular amine metabolic processGO:003324030.029
cellular response to external stimulusGO:00714961180.029
secretion by cellGO:00329402480.028
regulation of cell projection organizationGO:00313441750.028
neuron projection developmentGO:00311752730.028
cellular response to lipidGO:00713962010.028
wound healingGO:00420601220.028
positive regulation of mapk cascadeGO:0043410920.028
neural crest cell migrationGO:000175510.028
response to cadmium ionGO:0046686350.028
negative regulation of nucleic acid templated transcriptionGO:19035071170.027
positive regulation of mesenchymal cell proliferationGO:000205340.027
gastrulationGO:000736920.027
regulation of interleukin 1 secretionGO:005070430.027
metal ion transportGO:00300012890.027
cell part morphogenesisGO:00329901230.027
regulation of cellular component movementGO:00512701500.027
response to estrogenGO:00436272320.027
response to corticosteroidGO:00319602350.027
reactive oxygen species biosynthetic processGO:190340980.027
memoryGO:0007613540.027
dna metabolic processGO:0006259960.026
cellular macromolecule localizationGO:00707271220.026
neuron projection morphogenesisGO:00488121220.026
positive regulation of innate immune responseGO:0045089110.026
tube morphogenesisGO:0035239230.026
vesicle mediated transportGO:00161921810.026
camera type eye developmentGO:0043010480.026
sexual reproductionGO:00199531480.026
epiboly involved in wound healingGO:009050520.026
regulation of cellular component biogenesisGO:0044087860.026
ribose phosphate metabolic processGO:00196932350.026
positive regulation of ion transportGO:0043270940.026
bmp signaling pathwayGO:003050940.025
positive regulation of cell projection organizationGO:00313461110.025
response to molecule of bacterial originGO:00022371940.025
multi multicellular organism processGO:00447061380.025
regulation of intracellular signal transductionGO:19025312180.025
neuron deathGO:00709971270.025
negative regulation of signal transductionGO:0009968830.025
positive regulation of neuron projection developmentGO:0010976990.025
actin cytoskeleton organizationGO:0030036730.025
cellular response to abiotic stimulusGO:0071214850.024
regulation of immune system processGO:00026821230.024
lipid metabolic processGO:00066292830.024
regulation of protein targetingGO:1903533280.024
negative regulation of cell proliferationGO:00082851190.024
regulation of protein localizationGO:0032880810.024
response to oxidative stressGO:00069791860.024
striated muscle tissue developmentGO:0014706580.024
regulation of organ morphogenesisGO:2000027220.024
glial cell differentiationGO:0010001650.023
cellular response to cytokine stimulusGO:00713451270.023
regulation of locomotionGO:00400121480.023
response to cytokineGO:00340972150.023
regulation of defense responseGO:0031347680.023
actin filament based processGO:0030029860.023
negative regulation of nucleobase containing compound metabolic processGO:00459341530.023
muscle cell differentiationGO:0042692520.023
nucleobase containing small molecule metabolic processGO:00550863160.023
peptide biosynthetic processGO:004304330.023
generation of precursor metabolites and energyGO:0006091620.023
regulation of lipid metabolic processGO:0019216680.023
positive regulation of protein modification processGO:00314011420.022
epithelial cell differentiationGO:0030855710.022
regulation of membrane potentialGO:00423911100.022
purine nucleoside metabolic processGO:00422781690.022
gliogenesisGO:0042063930.022
small gtpase mediated signal transductionGO:0007264360.022
morphogenesis of embryonic epitheliumGO:001633130.022
g protein coupled receptor signaling pathwayGO:00071862420.022
regulation of protein kinase activityGO:00458591050.022
cellular macromolecular complex assemblyGO:0034622580.022
macroautophagyGO:001623640.021
peptide metabolic processGO:0006518320.021
somatic stem cell maintenanceGO:003501920.021
regulation of dendrite developmentGO:0050773590.021
positive regulation of immune responseGO:0050778420.021
regulation of cytokine productionGO:0001817560.021
positive regulation of apoptotic signaling pathwayGO:200123560.021
regulation of mesenchymal cell proliferationGO:001046440.021
regulation of innate immune responseGO:0045088150.021
response to amineGO:0014075460.021
response to hydrogen peroxideGO:0042542890.021
regulation of response to external stimulusGO:00321011060.021
response to transition metal nanoparticleGO:19902671220.021
neuron apoptotic processGO:0051402880.021
male sex differentiationGO:0046661640.021
carbohydrate metabolic processGO:00059751300.020
regulation of neurogenesisGO:00507672470.020
purine ribonucleotide metabolic processGO:00091502270.020
neural crest cell differentiationGO:001403320.020
negative regulation of cell communicationGO:00106481580.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
syncytium formation by plasma membrane fusionGO:000076830.020
regulation of lipid biosynthetic processGO:0046890380.020
hormone metabolic processGO:0042445690.020
positive regulation of interleukin 1 secretionGO:005071630.020
nucleoside phosphate metabolic processGO:00067532830.020
positive regulation of neuron differentiationGO:00456661260.020
positive regulation of cellular component biogenesisGO:0044089550.020
negative regulation of rna metabolic processGO:00512531230.020
cellular nitrogen compound catabolic processGO:00442701630.020
intracellular protein transportGO:0006886790.020
regulation of kinase activityGO:00435491170.020
regulation of hydrolase activityGO:00513361430.020
regulation of ion transportGO:00432692450.020
ossificationGO:0001503700.019
positive regulation of growthGO:0045927550.019
cytoplasmic transportGO:00164821150.019
cardiac chamber developmentGO:000320510.019
organophosphate biosynthetic processGO:00904071430.019
respiratory system developmentGO:0060541450.019
response to nutrientGO:00075842480.019
tube developmentGO:0035295890.019
digestive tract developmentGO:0048565390.019
endocytosisGO:0006897840.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
regulation of hormone levelsGO:00108171870.019
synaptic transmissionGO:00072682350.019
endomembrane system organizationGO:0010256480.019
regulation of leukocyte differentiationGO:1902105200.019
heart morphogenesisGO:000300730.019
regulation of endothelial cell differentiationGO:004560140.019
nucleoside metabolic processGO:00091161790.019
regulation of apoptotic signaling pathwayGO:2001233130.019
circadian sleep wake cycle processGO:0022410210.019
oxidation reduction processGO:00551143040.019
regulation of cell cycleGO:0051726730.019
carbohydrate homeostasisGO:0033500750.018
organonitrogen compound biosynthetic processGO:19015661670.018
positive regulation of locomotionGO:00400171020.018
skeletal muscle organ developmentGO:0060538330.018
regulation of organelle organizationGO:0033043800.018
purine ribonucleoside catabolic processGO:00461301240.018
neural crest cell developmentGO:001403220.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
b cell differentiationGO:003018320.018
circulatory system developmentGO:00723591340.018
response to gamma radiationGO:0010332240.018
regulation of developmental growthGO:0048638450.018
response to acid chemicalGO:00011012220.018
negative regulation of transportGO:00510511360.018
purine ribonucleoside triphosphate metabolic processGO:00092051400.018
response to estradiolGO:00323551640.018
regulation of skeletal muscle tissue regenerationGO:004341620.017
negative regulation of signalingGO:00230571570.017
response to anoxiaGO:003405940.017
forebrain developmentGO:0030900980.017
metanephric epithelium developmentGO:007220740.017
single organism nuclear importGO:1902593350.017
response to radiationGO:00093141370.017
monocarboxylic acid metabolic processGO:00327871520.017
establishment of protein localizationGO:00451841410.017
metal ion homeostasisGO:00550651860.017
interleukin 1 beta secretionGO:005070230.017
glycosyl compound metabolic processGO:19016571820.017
regulation of anatomical structure sizeGO:00900661350.016
nuclear importGO:0051170350.016
embryonic skeletal system morphogenesisGO:004870430.016
response to ionizing radiationGO:0010212590.016
regulation of dna metabolic processGO:0051052600.016
transforming growth factor beta receptor signaling pathwayGO:0007179180.016
embryonic cranial skeleton morphogenesisGO:004870120.016
defense response to other organismGO:0098542170.016
regulation of body fluid levelsGO:0050878900.016
jnk cascadeGO:0007254280.016
positive regulation of neuron deathGO:1901216430.016
regulation of neuron projection developmentGO:00109751610.016
sulfur compound metabolic processGO:0006790700.016
regulation of cellular response to stressGO:0080135490.016
protein localization to organelleGO:0033365570.016
circadian rhythmGO:0007623880.016
female gamete generationGO:0007292250.016
defense response to gram negative bacteriumGO:005082930.016
activation of cysteine type endopeptidase activityGO:009720240.016
response to transforming growth factor betaGO:0071559460.016
carbohydrate derivative biosynthetic processGO:19011371240.016
appendage morphogenesisGO:003510740.016
cellular metal ion homeostasisGO:00068751720.016
cytokine secretionGO:0050663150.016
negative regulation of mitotic cell cycle phase transitionGO:190199130.015
divalent inorganic cation homeostasisGO:00725071650.015
lipid storageGO:001991510.015
kidney epithelium developmentGO:0072073190.015
reactive oxygen species metabolic processGO:0072593370.015

Lig3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
connective tissue diseaseDOID:6500.030
musculoskeletal system diseaseDOID:1700.030
disease of anatomical entityDOID:700.030
organ system cancerDOID:005068600.027
disease of cellular proliferationDOID:1456600.027
cancerDOID:16200.027
gastrointestinal system cancerDOID:311900.027
liver cancerDOID:357100.027
cardiovascular system diseaseDOID:128700.024
nervous system diseaseDOID:86300.018
sensory system diseaseDOID:005015500.018
disease of metabolismDOID:001466700.016