IMP: Integrative Multi-species Prediction

Rattus norvegicus

81 known processes

Aoc3

amine oxidase, copper containing 3 (vascular adhesion protein 1)

(Aliases: SSAO)

RGD: 62058
Entrez: 29473
UniProtKB: O08590

Process Predictions
Disease Predictions

Aoc3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein transport	GO:0015031	132	0.167
macromolecule localization	GO:0033036	252	0.147
protein localization	GO:0008104	191	0.126
response to nutrient	GO:0007584	248	0.114
response to extracellular stimulus	GO:0009991	380	0.103	Rat
response to wounding	GO:0009611	254	0.102
regulation of phosphate metabolic process	GO:0019220	349	0.087
regulation of cellular protein metabolic process	GO:0032268	267	0.087
intracellular signal transduction	GO:0035556	314	0.081
transcription dna templated	GO:0006351	377	0.080
response to glucocorticoid	GO:0051384	223	0.078
response to nutrient levels	GO:0031667	370	0.077	Rat
regulation of phosphorylation	GO:0042325	248	0.077
regeneration	GO:0031099	163	0.077
cellular response to endogenous stimulus	GO:0071495	377	0.077
protein phosphorylation	GO:0006468	345	0.075
rna biosynthetic process	GO:0032774	380	0.074
response to peptide hormone	GO:0043434	278	0.073
reproductive process	GO:0022414	372	0.071
cellular response to hormone stimulus	GO:0032870	247	0.069
cellular response to organonitrogen compound	GO:0071417	197	0.069
regulation of phosphorus metabolic process	GO:0051174	349	0.068
positive regulation of biosynthetic process	GO:0009891	319	0.068
establishment of protein localization	GO:0045184	141	0.068
regulation of cellular amine metabolic process	GO:0033238	8	0.067
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.063
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.062
cellular response to nitrogen compound	GO:1901699	210	0.062
multi multicellular organism process	GO:0044706	138	0.061
cellular component biogenesis	GO:0044085	368	0.061
negative regulation of cell proliferation	GO:0008285	119	0.060
response to inorganic substance	GO:0010035	377	0.060
positive regulation of phosphate metabolic process	GO:0045937	262	0.060
positive regulation of signal transduction	GO:0009967	175	0.060
response to external biotic stimulus	GO:0043207	221	0.059
regulation of cell growth	GO:0001558	85	0.056
response to peptide	GO:1901652	292	0.056
regulation of cellular ketone metabolic process	GO:0010565	27	0.056
muscle tissue development	GO:0060537	58	0.055
regulation of response to stress	GO:0080134	126	0.054
cellular protein localization	GO:0034613	122	0.054
regulation of programmed cell death	GO:0043067	341	0.053
regulation of protein metabolic process	GO:0051246	289	0.053
regulation of cellular component organization	GO:0051128	368	0.053
cellular amino acid metabolic process	GO:0006520	107	0.052
cellular response to insulin stimulus	GO:0032869	81	0.052
nucleic acid templated transcription	GO:0097659	379	0.051
positive regulation of cellular protein metabolic process	GO:0032270	167	0.050
cellular component assembly	GO:0022607	360	0.050
response to molecule of bacterial origin	GO:0002237	194	0.049
positive regulation of multicellular organismal process	GO:0051240	387	0.049
positive regulation of cellular biosynthetic process	GO:0031328	295	0.049
regulation of protein modification process	GO:0031399	194	0.049
cell growth	GO:0016049	104	0.047
catabolic process	GO:0009056	351	0.047
regulation of apoptotic process	GO:0042981	335	0.046
macromolecular complex assembly	GO:0065003	273	0.046
positive regulation of phosphorus metabolic process	GO:0010562	262	0.046
regulation of cell proliferation	GO:0042127	359	0.045
negative regulation of metabolic process	GO:0009892	331	0.045
regulation of rna metabolic process	GO:0051252	391	0.045
cell type specific apoptotic process	GO:0097285	134	0.045
cellular response to oxygen containing compound	GO:1901701	386	0.044
regulation of immune system process	GO:0002682	123	0.043
regulation of cellular amino acid metabolic process	GO:0006521	2	0.043
response to corticosteroid	GO:0031960	235	0.043
negative regulation of multicellular organismal process	GO:0051241	203	0.043
response to biotic stimulus	GO:0009607	226	0.043
response to mechanical stimulus	GO:0009612	134	0.042
regulation of signal transduction	GO:0009966	318	0.042
response to other organism	GO:0051707	220	0.042
aging	GO:0007568	241	0.041
positive regulation of phosphorylation	GO:0042327	177	0.040
cellular macromolecule localization	GO:0070727	122	0.040
amine metabolic process	GO:0009308	38	0.040
response to cytokine	GO:0034097	215	0.040
regulation of protein phosphorylation	GO:0001932	183	0.039
negative regulation of cell communication	GO:0010648	158	0.039
cardiovascular system development	GO:0072358	134	0.038
protein complex assembly	GO:0006461	263	0.038
single organism intracellular transport	GO:1902582	166	0.038
cellular response to peptide hormone stimulus	GO:0071375	120	0.038
neuron differentiation	GO:0030182	368	0.037
response to lipopolysaccharide	GO:0032496	191	0.037
positive regulation of response to stimulus	GO:0048584	285	0.036
secretion	GO:0046903	307	0.036
single organism cellular localization	GO:1902580	102	0.036
regulation of cell differentiation	GO:0045595	320	0.035
negative regulation of programmed cell death	GO:0043069	183	0.035
response to temperature stimulus	GO:0009266	94	0.035
cation transport	GO:0006812	382	0.034
programmed cell death	GO:0012501	392	0.034
response to decreased oxygen levels	GO:0036293	237	0.034
positive regulation of protein metabolic process	GO:0051247	178	0.034
muscle structure development	GO:0061061	87	0.034
regulation of rna biosynthetic process	GO:2001141	381	0.034
response to hypoxia	GO:0001666	231	0.033
regulation of molecular function	GO:0065009	398	0.033
apoptotic process	GO:0006915	381	0.031
response to bacterium	GO:0009617	200	0.030
positive regulation of cellular amine metabolic process	GO:0033240	3	0.030
regulation of multicellular organismal development	GO:2000026	376	0.030
positive regulation of developmental process	GO:0051094	283	0.030
rna metabolic process	GO:0016070	406	0.029
intracellular transport	GO:0046907	185	0.029
anatomical structure morphogenesis	GO:0009653	298	0.028
regulation of transforming growth factor beta receptor signaling pathway	GO:0017015	5	0.028
cellular response to peptide	GO:1901653	133	0.028
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.028
regulation of cell development	GO:0060284	263	0.028
response to oxygen levels	GO:0070482	265	0.028
positive regulation of transcription dna templated	GO:0045893	197	0.028
carbohydrate derivative metabolic process	GO:1901135	346	0.027	Rat
female pregnancy	GO:0007565	122	0.027
neuron development	GO:0048666	286	0.027
protein oligomerization	GO:0051259	191	0.027
carboxylic acid metabolic process	GO:0019752	289	0.027
transmission of nerve impulse	GO:0019226	42	0.027
positive regulation of rna metabolic process	GO:0051254	203	0.027
cellular catabolic process	GO:0044248	295	0.027
cellular response to organic cyclic compound	GO:0071407	202	0.026
cell adhesion	GO:0007155	110	0.026
organ regeneration	GO:0031100	101	0.026
positive regulation of protein phosphorylation	GO:0001934	135	0.026
blood circulation	GO:0008015	183	0.026
nucleotide metabolic process	GO:0009117	279	0.026
positive regulation of gene expression	GO:0010628	244	0.026
oxoacid metabolic process	GO:0043436	290	0.026
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.026
protein complex biogenesis	GO:0070271	263	0.026
response to vitamin	GO:0033273	131	0.025
cellular amine metabolic process	GO:0044106	38	0.025
positive regulation of signaling	GO:0023056	270	0.025
response to organophosphorus	GO:0046683	102	0.025
maintenance of location	GO:0051235	17	0.025
central nervous system development	GO:0007417	311	0.025
regulation of growth	GO:0040008	105	0.025
circulatory system development	GO:0072359	134	0.025
response to amino acid	GO:0043200	75	0.025
positive regulation of cell death	GO:0010942	184	0.025
regulation of membrane potential	GO:0042391	110	0.025
cellular ketone metabolic process	GO:0042180	51	0.025
multi organism reproductive process	GO:0044703	262	0.024
regulation of transcription dna templated	GO:0006355	374	0.024
positive regulation of protein modification process	GO:0031401	142	0.024
organic substance catabolic process	GO:1901575	316	0.024
negative regulation of macromolecule metabolic process	GO:0010605	260	0.024
positive regulation of transport	GO:0051050	245	0.024
regulation of smooth muscle cell proliferation	GO:0048660	75	0.024
regulation of cellular localization	GO:0060341	263	0.024
nucleobase containing small molecule metabolic process	GO:0055086	316	0.024
organelle organization	GO:0006996	266	0.024
response to camp	GO:0051591	91	0.023
actin filament based process	GO:0030029	86	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.023
rhythmic process	GO:0048511	156	0.023
positive regulation of catalytic activity	GO:0043085	184	0.023
positive regulation of cellular component organization	GO:0051130	200	0.022
regulation of nucleic acid templated transcription	GO:1903506	380	0.022
inflammatory response	GO:0006954	150	0.022
regulation of intracellular signal transduction	GO:1902531	218	0.022
cell projection organization	GO:0030030	302	0.021
tissue regeneration	GO:0042246	36	0.021
peptidyl amino acid modification	GO:0018193	126	0.021
response to transforming growth factor beta	GO:0071559	46	0.021
tissue development	GO:0009888	252	0.020
intracellular protein transport	GO:0006886	79	0.020
actin cytoskeleton organization	GO:0030036	73	0.020
anion transport	GO:0006820	178	0.020
positive regulation of secretion	GO:0051047	140	0.020
negative regulation of cell differentiation	GO:0045596	99	0.020
vascular process in circulatory system	GO:0003018	96	0.020
single organism biosynthetic process	GO:0044711	342	0.020	Rat
positive regulation of apoptotic process	GO:0043065	154	0.020
negative regulation of cardiac muscle tissue development	GO:0055026	3	0.020
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.020
response to ketone	GO:1901654	182	0.020
cellular component movement	GO:0006928	248	0.020
wound healing	GO:0042060	122	0.019
positive regulation of cell communication	GO:0010647	271	0.019
transcription from rna polymerase ii promoter	GO:0006366	252	0.019
neuronal action potential	GO:0019228	35	0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.019
protein complex subunit organization	GO:0071822	302	0.019
regulation of nervous system development	GO:0051960	264	0.019
circadian rhythm	GO:0007623	88	0.019
positive regulation of rna biosynthetic process	GO:1902680	197	0.019
response to acid chemical	GO:0001101	222	0.019
negative regulation of response to stimulus	GO:0048585	155	0.019
biological adhesion	GO:0022610	110	0.019
positive regulation of locomotion	GO:0040017	102	0.018
single organism catabolic process	GO:0044712	283	0.018
cellular response to stress	GO:0033554	269	0.018
transmembrane transport	GO:0055085	412	0.018
insulin receptor signaling pathway	GO:0008286	24	0.018
endocytosis	GO:0006897	84	0.018
cytoskeleton organization	GO:0007010	111	0.018
response to growth factor	GO:0070848	189	0.018
response to heat	GO:0009408	60	0.018
peptidyl tyrosine modification	GO:0018212	72	0.018
cellular response to cytokine stimulus	GO:0071345	127	0.017
response to ethanol	GO:0045471	162	0.017
smooth muscle cell proliferation	GO:0048659	77	0.017
regulation of protein maturation	GO:1903317	50	0.017
positive regulation of cell differentiation	GO:0045597	217	0.017
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.017
regulation of neurogenesis	GO:0050767	247	0.017
positive regulation of cell proliferation	GO:0008284	249	0.016
organic acid metabolic process	GO:0006082	292	0.016
multicellular organism growth	GO:0035264	1	0.016
ras protein signal transduction	GO:0007265	29	0.016
striated muscle tissue development	GO:0014706	58	0.016
negative regulation of heart growth	GO:0061117	3	0.016
g protein coupled receptor signaling pathway	GO:0007186	242	0.016
positive regulation of cell development	GO:0010720	176	0.016
multicellular organismal signaling	GO:0035637	44	0.016
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.016
vesicle mediated transport	GO:0016192	181	0.016
regulation of tube size	GO:0035150	89	0.016
negative regulation of protein metabolic process	GO:0051248	114	0.016
negative regulation of developmental process	GO:0051093	125	0.015
negative regulation of cardiac muscle tissue growth	GO:0055022	3	0.015
response to estrogen	GO:0043627	232	0.015
heart development	GO:0007507	72	0.015
carbohydrate metabolic process	GO:0005975	130	0.015	Rat
response to purine containing compound	GO:0014074	126	0.015
regulation of ion transport	GO:0043269	245	0.015
secretion by cell	GO:0032940	248	0.015
response to estradiol	GO:0032355	164	0.015
regulation of protein localization	GO:0032880	81	0.015
synaptic growth at neuromuscular junction	GO:0051124	1	0.015
ribose phosphate metabolic process	GO:0019693	235	0.015
multicellular organism reproduction	GO:0032504	233	0.015
response to carbohydrate	GO:0009743	183	0.015
protein localization to organelle	GO:0033365	57	0.015
action potential	GO:0001508	54	0.015
regulation of canonical wnt signaling pathway	GO:0060828	4	0.015
cytoplasmic transport	GO:0016482	115	0.015
positive regulation of cell migration	GO:0030335	96	0.015
response to metal ion	GO:0010038	253	0.015
respiratory system development	GO:0060541	45	0.015
developmental growth	GO:0048589	100	0.014
regulation of establishment of protein localization	GO:0070201	69	0.014
developmental induction	GO:0031128	2	0.014
negative regulation of cellular metabolic process	GO:0031324	281	0.014
response to retinoic acid	GO:0032526	63	0.014
regulation of cardiac muscle tissue development	GO:0055024	12	0.014
proteolysis	GO:0006508	175	0.014
negative regulation of gene expression	GO:0010629	199	0.014
regulation of cellular response to growth factor stimulus	GO:0090287	15	0.014
positive regulation of molecular function	GO:0044093	230	0.014
ribonucleotide metabolic process	GO:0009259	231	0.014
response to monosaccharide	GO:0034284	159	0.014
small gtpase mediated signal transduction	GO:0007264	36	0.014
positive regulation of programmed cell death	GO:0043068	157	0.014
lipid metabolic process	GO:0006629	283	0.013
carbohydrate derivative biosynthetic process	GO:1901137	124	0.013
organophosphate biosynthetic process	GO:0090407	143	0.013
regulation of catalytic activity	GO:0050790	304	0.013
localization of cell	GO:0051674	202	0.013
cellular response to growth factor stimulus	GO:0071363	162	0.013
response to activity	GO:0014823	73	0.013
regulation of secretion	GO:0051046	224	0.013
nucleoside phosphate metabolic process	GO:0006753	283	0.013
immune system process	GO:0002376	204	0.013
metal ion transport	GO:0030001	289	0.013
limb morphogenesis	GO:0035108	4	0.013
muscle cell proliferation	GO:0033002	84	0.013
regulation of kinase activity	GO:0043549	117	0.013
response to low density lipoprotein particle	GO:0055098	4	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
negative regulation of apoptotic process	GO:0043066	181	0.013
cellular response to external stimulus	GO:0071496	118	0.013
negative regulation of phosphorylation	GO:0042326	57	0.013
cellular response to alcohol	GO:0097306	87	0.013
protein heterooligomerization	GO:0051291	89	0.012
regulation of neuron differentiation	GO:0045664	208	0.012
growth	GO:0040007	165	0.012
regulation of intracellular transport	GO:0032386	65	0.012
regulation of phagocytosis engulfment	GO:0060099	4	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012
regulation of ossification	GO:0030278	32	0.012
negative regulation of signaling	GO:0023057	157	0.012
bmp signaling pathway	GO:0030509	4	0.012
axis specification	GO:0009798	4	0.012
negative regulation of cell death	GO:0060548	229	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.012
cellular response to acid chemical	GO:0071229	75	0.012
cellular response to abiotic stimulus	GO:0071214	85	0.012
purine nucleotide biosynthetic process	GO:0006164	83	0.012
head development	GO:0060322	247	0.012
protein homooligomerization	GO:0051260	91	0.012
response to radiation	GO:0009314	137	0.012
reproduction	GO:0000003	245	0.012
regulation of stem cell differentiation	GO:2000736	2	0.012
nucleotide biosynthetic process	GO:0009165	98	0.012
positive regulation of cell motility	GO:2000147	97	0.012
liver development	GO:0001889	90	0.012
embryonic limb morphogenesis	GO:0030326	4	0.012
ion transmembrane transport	GO:0034220	365	0.012
reactive oxygen species metabolic process	GO:0072593	37	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
peptidyl tyrosine phosphorylation	GO:0018108	72	0.012
regulation of neuron death	GO:1901214	115	0.012
macromolecular complex subunit organization	GO:0043933	339	0.011
response to oxidative stress	GO:0006979	186	0.011
cellular response to steroid hormone stimulus	GO:0071383	93	0.011
organ induction	GO:0001759	1	0.011
cellular homeostasis	GO:0019725	252	0.011
negative regulation of osteoblast differentiation	GO:0045668	2	0.011
negative regulation of organ growth	GO:0046621	3	0.011
organophosphate metabolic process	GO:0019637	370	0.011	Rat
positive regulation of immune system process	GO:0002684	90	0.011
retinal metabolic process	GO:0042574	3	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.011
nucleoside phosphate biosynthetic process	GO:1901293	102	0.011
protein maturation	GO:0051604	68	0.011
positive regulation of intracellular signal transduction	GO:1902533	138	0.011
regulation of blood vessel size	GO:0050880	89	0.011
regulation of secretion by cell	GO:1903530	208	0.011
regulation of anatomical structure size	GO:0090066	135	0.011
purine ribonucleotide metabolic process	GO:0009150	227	0.011
single organism reproductive process	GO:0044702	297	0.011
positive regulation of secretion by cell	GO:1903532	128	0.011
regulation of osteoblast differentiation	GO:0045667	14	0.011
regulation of bmp signaling pathway	GO:0030510	2	0.011
divalent inorganic cation transport	GO:0072511	134	0.011
ribose phosphate biosynthetic process	GO:0046390	87	0.011
formation of primary germ layer	GO:0001704	1	0.011
regulation of cellular component biogenesis	GO:0044087	86	0.011
regulation of endocytosis	GO:0030100	42	0.011
negative regulation of signal transduction	GO:0009968	83	0.011
skeletal muscle tissue development	GO:0007519	31	0.010
purine nucleotide metabolic process	GO:0006163	229	0.010
protein processing	GO:0016485	68	0.010
neuron projection development	GO:0031175	273	0.010
cytokine production	GO:0001816	61	0.010
regulation of systemic arterial blood pressure by circulatory renin angiotensin	GO:0001991	4	0.010
negative regulation of phosphorus metabolic process	GO:0010563	80	0.010
striated muscle cell differentiation	GO:0051146	39	0.010
negative regulation of phosphate metabolic process	GO:0045936	80	0.010
lipid storage	GO:0019915	1	0.010
negative regulation of biosynthetic process	GO:0009890	168	0.010
regulation of body fluid levels	GO:0050878	90	0.010
positive regulation of cellular component biogenesis	GO:0044089	55	0.010
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.010
forebrain development	GO:0030900	98	0.010

Aoc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
muscle tissue disease	DOID:66	0.091
disease of anatomical entity	DOID:7	0.091
muscular dystrophy	DOID:9884	0.091
muscular disease	DOID:0080000	0.091
myopathy	DOID:423	0.091
musculoskeletal system disease	DOID:17	0.091
nervous system disease	DOID:863	0.028
cardiovascular system disease	DOID:1287	0.016
essential hypertension	DOID:10825	0.016
vascular disease	DOID:178	0.016
hypertension	DOID:10763	0.016
artery disease	DOID:0050828	0.016
disease of metabolism	DOID:0014667	0.010

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