Rattus norvegicus

120 known processes

Hmgcs2

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)

(Aliases: Hmgcs1,Mt3h3mg)

Hmgcs2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monocarboxylic acid metabolic processGO:00327871520.683
cellular lipid metabolic processGO:00442552080.648
organic acid metabolic processGO:00060822920.597
oxoacid metabolic processGO:00434362900.529
response to nutrient levelsGO:00316673700.449
acylglycerol metabolic processGO:0006639210.440
long chain fatty acid metabolic processGO:0001676320.404
cellular lipid catabolic processGO:0044242370.343
cellular catabolic processGO:00442482950.336
lipid metabolic processGO:00066292830.330
monocarboxylic acid catabolic processGO:0072329280.297
fatty acid beta oxidationGO:0006635220.294
carboxylic acid metabolic processGO:00197522890.275
organic acid catabolic processGO:0016054490.228
cellular response to lipidGO:00713962010.227
oxidation reduction processGO:00551143040.222
single organism biosynthetic processGO:00447113420.221
fatty acid oxidationGO:0019395290.209
response to corticosteroidGO:00319602350.204
catabolic processGO:00090563510.181
response to acid chemicalGO:00011012220.171
fatty acid metabolic processGO:0006631990.169
response to metal ionGO:00100382530.160
cellular response to oxygen containing compoundGO:19017013860.154
response to hypoxiaGO:00016662310.154
response to extracellular stimulusGO:00099913800.154
agingGO:00075682410.144
response to inorganic substanceGO:00100353770.143
response to glucocorticoidGO:00513842230.140
organic hydroxy compound metabolic processGO:19016151150.139
response to decreased oxygen levelsGO:00362932370.138
cellular response to organic cyclic compoundGO:00714072020.137
response to other organismGO:00517072200.129
response to oxygen levelsGO:00704822650.129
neutral lipid metabolic processGO:0006638210.127
glycerolipid metabolic processGO:0046486670.126
lipid modificationGO:0030258520.126
organic substance catabolic processGO:19015753160.119
small molecule catabolic processGO:0044282590.112
reproductive processGO:00224143720.112
Rat
triglyceride metabolic processGO:0006641210.111
response to campGO:0051591910.107
liver developmentGO:0001889900.101
positive regulation of fatty acid beta oxidationGO:003200040.101
sulfur compound metabolic processGO:0006790700.100
protein oligomerizationGO:00512591910.098
protein complex assemblyGO:00064612630.094
response to peptideGO:19016522920.093
response to biotic stimulusGO:00096072260.093
response to toxic substanceGO:00096361330.092
regulation of hormone levelsGO:00108171870.091
neurological system processGO:00508772190.089
multicellular organism reproductionGO:00325042330.087
antral ovarian follicle growthGO:000154730.081
single organism catabolic processGO:00447122830.081
regulation of apoptotic processGO:00429813350.078
multi organism reproductive processGO:00447032620.076
nitrogen compound transportGO:00717052290.074
gland developmentGO:00487321550.073
response to insecticideGO:0017085210.073
macromolecular complex assemblyGO:00650032730.073
programmed cell deathGO:00125013920.070
macromolecular complex subunit organizationGO:00439333390.070
secretionGO:00469033070.070
positive regulation of lipid catabolic processGO:005099640.070
steroid metabolic processGO:0008202730.069
response to ethanolGO:00454711620.068
cellular ketone metabolic processGO:0042180510.066
response to peptide hormoneGO:00434342780.065
lipid localizationGO:0010876620.064
regulation of cell proliferationGO:00421273590.064
carboxylic acid biosynthetic processGO:0046394830.063
protein complex biogenesisGO:00702712630.062
response to woundingGO:00096112540.061
response to fatty acidGO:0070542650.060
reproductive system developmentGO:00614581280.058
Rat
lipid catabolic processGO:0016042460.058
organic acid transportGO:00158491160.056
regulation of catalytic activityGO:00507903040.056
phenol containing compound metabolic processGO:0018958300.056
apoptotic processGO:00069153810.055
reproductionGO:00000032450.055
cellular component biogenesisGO:00440853680.055
cell cell signalingGO:00072673350.053
cofactor metabolic processGO:0051186950.053
single organism behaviorGO:00447081300.053
regulation of secretion by cellGO:19035302080.051
circulatory system processGO:00030131830.050
carbohydrate metabolic processGO:00059751300.049
protein homooligomerizationGO:0051260910.049
female pregnancyGO:00075651220.048
carboxylic acid transportGO:00469421150.047
cellular hormone metabolic processGO:0034754490.047
lipid transportGO:0006869610.046
sex differentiationGO:00075481130.046
Rat
chemical homeostasisGO:00488782920.046
response to molecule of bacterial originGO:00022371940.045
coenzyme metabolic processGO:0006732860.045
xenobiotic metabolic processGO:0006805190.045
organic anion transportGO:00157111320.044
amine metabolic processGO:0009308380.044
multicellular organismal reproductive processGO:00486092330.042
single organism reproductive processGO:00447022970.042
Rat
linoleic acid metabolic processGO:004365140.041
sulfur compound biosynthetic processGO:0044272190.041
cellular amine metabolic processGO:0044106380.040
carboxylic acid catabolic processGO:0046395490.040
single organism carbohydrate metabolic processGO:00447231180.040
lipid oxidationGO:0034440300.040
neurotransmitter biosynthetic processGO:004213620.039
cognitionGO:0050890920.039
gonad developmentGO:00084061040.039
Rat
regulation of cellular ketone metabolic processGO:0010565270.039
head developmentGO:00603222470.039
cellular amino acid metabolic processGO:00065201070.039
developmental process involved in reproductionGO:00030061590.039
Rat
peptide hormone secretionGO:0030072840.038
regenerationGO:00310991630.038
epithelial cell differentiationGO:0030855710.038
protein complex subunit organizationGO:00718223020.038
hexose metabolic processGO:0019318580.037
anion transportGO:00068201780.037
monocarboxylic acid transportGO:0015718520.037
response to external biotic stimulusGO:00432072210.037
cellular response to peptide hormone stimulusGO:00713751200.036
response to vitaminGO:00332731310.036
Rat
regulation of cellular catabolic processGO:00313291010.036
epithelium developmentGO:0060429960.035
cellular component assemblyGO:00226073600.035
feeding behaviorGO:0007631530.035
regulation of programmed cell deathGO:00430673410.035
amide transportGO:00428861050.035
blood circulationGO:00080151830.034
regulation of hormone secretionGO:00468831060.034
regulation of peptide hormone secretionGO:0090276800.034
organophosphate metabolic processGO:00196373700.033
sulfur amino acid metabolic processGO:000009690.033
hepaticobiliary system developmentGO:0061008900.033
drug metabolic processGO:0017144110.032
isoprenoid metabolic processGO:0006720450.032
development of primary sexual characteristicsGO:00451371070.032
Rat
regulation of fatty acid metabolic processGO:0019217180.032
regulation of anatomical structure sizeGO:00900661350.032
regulation of cellular amine metabolic processGO:003323880.031
secretion by cellGO:00329402480.031
cellular response to endogenous stimulusGO:00714953770.031
macromolecule localizationGO:00330362520.031
developmental growthGO:00485891000.031
terpenoid metabolic processGO:0006721370.031
regulation of molecular functionGO:00650093980.031
regulation of multicellular organismal developmentGO:20000263760.031
cellular modified amino acid metabolic processGO:0006575610.030
female gonad developmentGO:0008585530.030
central nervous system developmentGO:00074173110.030
multicellular organismal signalingGO:0035637440.029
positive regulation of cell deathGO:00109421840.029
regulation of lipid metabolic processGO:0019216680.029
amino acid betaine metabolic processGO:000657730.029
regulation of secretionGO:00510462240.029
response to transition metal nanoparticleGO:19902671220.029
regulation of blood pressureGO:0008217830.029
response to cytokineGO:00340972150.028
alcohol metabolic processGO:0006066770.028
intracellular signal transductionGO:00355563140.028
positive regulation of lipid metabolic processGO:0045834330.028
peptide secretionGO:0002790860.028
regulation of peptide secretionGO:0002791820.028
fatty acid catabolic processGO:0009062260.028
regulation of cellular amino acid metabolic processGO:000652120.027
learning or memoryGO:0007611900.027
behaviorGO:00076102050.027
response to carbohydrateGO:00097431830.027
negative regulation of programmed cell deathGO:00430691830.026
cellular response to external stimulusGO:00714961180.026
reproductive structure developmentGO:00486081280.026
Rat
inflammatory responseGO:00069541500.025
cellular response to hormone stimulusGO:00328702470.025
anatomical structure morphogenesisGO:00096532980.025
regulation of catabolic processGO:00098941130.025
regulation of cellular localizationGO:00603412630.025
negative regulation of metabolic processGO:00098923310.025
hormone transportGO:00099141210.024
hormone metabolic processGO:0042445690.024
cellular response to alcoholGO:0097306870.024
Rat
response to organophosphorusGO:00466831020.024
transmission of nerve impulseGO:0019226420.024
positive regulation of molecular functionGO:00440932300.024
neuron projection developmentGO:00311752730.024
negative regulation of apoptotic processGO:00430661810.024
regulation of membrane potentialGO:00423911100.024
growthGO:00400071650.023
g protein coupled receptor signaling pathwayGO:00071862420.023
peptide transportGO:0015833970.023
nucleobase containing small molecule metabolic processGO:00550863160.023
brain developmentGO:00074202470.023
organ regenerationGO:00311001010.023
negative regulation of multicellular organismal processGO:00512412030.023
response to herbicideGO:0009635160.023
cellular response to acid chemicalGO:0071229750.023
regulation of hydrolase activityGO:00513361430.023
rhythmic processGO:00485111560.023
regulation of neuron projection developmentGO:00109751610.023
regulation of body fluid levelsGO:0050878900.022
response to activityGO:0014823730.022
response to ketoneGO:19016541820.022
regulation of phosphorus metabolic processGO:00511743490.022
response to purine containing compoundGO:00140741260.022
organonitrogen compound biosynthetic processGO:19015661670.022
regulation of fatty acid beta oxidationGO:003199880.022
response to retinoic acidGO:0032526630.022
negative regulation of cellular metabolic processGO:00313242810.022
response to bacteriumGO:00096172000.022
transmembrane transportGO:00550854120.022
synaptic transmissionGO:00072682350.021
positive regulation of fatty acid oxidationGO:004632160.021
toxin metabolic processGO:000940490.021
regulation of neurogenesisGO:00507672470.021
small molecule biosynthetic processGO:00442831240.021
glucose metabolic processGO:0006006520.021
regulation of cell projection organizationGO:00313441750.021
signal releaseGO:00230611450.021
unsaturated fatty acid metabolic processGO:0033559390.020
cellular response to organonitrogen compoundGO:00714171970.020
regulation of protein metabolic processGO:00512462890.020
regulation of cellular protein metabolic processGO:00322682670.020
gamete generationGO:00072761240.020
naphthalene containing compound metabolic processGO:009042020.020
development of primary female sexual characteristicsGO:0046545560.020
female sex differentiationGO:0046660590.020
acetate ester metabolic processGO:190061940.020
regulation of nervous system developmentGO:00519602640.020
regulation of signal transductionGO:00099663180.020
multi multicellular organism processGO:00447061380.020
tissue developmentGO:00098882520.019
cellular response to nutrient levelsGO:0031669600.019
memoryGO:0007613540.019
regulation of cell developmentGO:00602842630.019
response to alkaloidGO:00432791320.019
carnitine metabolic processGO:000943730.019
acetylcholine biosynthetic processGO:000829220.019
positive regulation of biosynthetic processGO:00098913190.019
cellular amino acid biosynthetic processGO:0008652320.019
lipid biosynthetic processGO:00086101280.019
regulation of cell differentiationGO:00455953200.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
positive regulation of developmental processGO:00510942830.019
sexual reproductionGO:00199531480.019
positive regulation of catabolic processGO:0009896780.018
diterpenoid metabolic processGO:0016101330.018
nucleotide metabolic processGO:00091172790.018
neuron differentiationGO:00301823680.018
regulation of phosphorylationGO:00423252480.018
positive regulation of apoptotic processGO:00430651540.018
thioester metabolic processGO:0035383280.018
response to lipopolysaccharideGO:00324961910.018
positive regulation of cellular component organizationGO:00511302000.018
insulin secretionGO:0030073690.018
action potentialGO:0001508540.018
defense responseGO:00069521940.018
positive regulation of cellular amine metabolic processGO:003324030.017
organic acid biosynthetic processGO:0016053830.017
positive regulation of cellular catabolic processGO:0031331710.017
metal ion transportGO:00300012890.017
regulation of insulin secretionGO:0050796650.017
epithelial cell proliferationGO:0050673540.017
chlorinated hydrocarbon metabolic processGO:004219640.017
positive regulation of multicellular organismal processGO:00512403870.017
negative regulation of cell communicationGO:00106481580.017
neuron developmentGO:00486662860.017
regulation of protein modification processGO:00313991940.016
proteolysisGO:00065081750.016
negative regulation of cell deathGO:00605482290.016
heterocycle catabolic processGO:00467001670.016
response to estradiolGO:00323551640.016
response to estrogenGO:00436272320.016
long chain fatty acid transportGO:0015909140.016
response to nicotineGO:0035094510.016
naphthalene metabolic processGO:001893120.016
positive regulation of cell proliferationGO:00082842490.016
cellular response to extracellular stimulusGO:0031668730.016
heart morphogenesisGO:000300730.016
positive regulation of phosphorus metabolic processGO:00105622620.016
positive regulation of protein metabolic processGO:00512471780.016
cellular response to stressGO:00335542690.016
nucleoside phosphate metabolic processGO:00067532830.016
response to xenobiotic stimulusGO:0009410230.016
protein phosphorylationGO:00064683450.016
localization of cellGO:00516742020.016
regulation of synaptic transmissionGO:00508041410.016
response to oxidative stressGO:00069791860.016
positive regulation of cell developmentGO:00107201760.015
regulation of cellular component organizationGO:00511283680.015
negative regulation of signalingGO:00230571570.015
positive regulation of catalytic activityGO:00430851840.015
regulation of tube sizeGO:0035150890.015
hormone secretionGO:00468791150.015
regulation of neuron differentiationGO:00456642080.015
positive regulation of hydrolase activityGO:0051345860.015
positive regulation of phosphorylationGO:00423271770.015
response to osmotic stressGO:0006970420.015
organic cyclic compound catabolic processGO:19013611750.015
response to nutrientGO:00075842480.015
positive regulation of secretionGO:00510471400.015
regulation of peptide transportGO:0090087870.015
cellular response to corticosteroid stimulusGO:0071384690.015
regulation of growthGO:00400081050.015
carbohydrate derivative metabolic processGO:19011353460.014
regulation of system processGO:00440572080.014
positive regulation of cell communicationGO:00106472710.014
response to hexoseGO:00097461440.014
ion transmembrane transportGO:00342203650.014
regulation of phosphate metabolic processGO:00192203490.014
mapk cascadeGO:00001651400.014
reactive nitrogen species metabolic processGO:200105710.014
regulation of neurotransmitter levelsGO:0001505420.014
response to growth factorGO:00708481890.014
insecticide metabolic processGO:001714340.014
ras protein signal transductionGO:0007265290.014
response to insulinGO:00328681330.014
regulation of protein phosphorylationGO:00019321830.014
neuronal action potentialGO:0019228350.013
c21 steroid hormone biosynthetic processGO:0006700100.013
organonitrogen compound catabolic processGO:19015651790.013
regulation of intracellular signal transductionGO:19025312180.013
response to testosteroneGO:0033574550.013
positive regulation of response to stimulusGO:00485842850.013
organophosphate catabolic processGO:00464341480.013
regulation of rna biosynthetic processGO:20011413810.013
acetyl coa metabolic processGO:0006084170.013
endothelial cell apoptotic processGO:007257730.013
vesicle mediated transportGO:00161921810.013
negative regulation of macromolecule metabolic processGO:00106052600.013
cation transportGO:00068123820.013
regulation of transcription dna templatedGO:00063553740.013
cellular response to glucocorticoid stimulusGO:0071385680.013
positive regulation of nervous system developmentGO:00519621780.013
estrogen metabolic processGO:0008210110.012
response to mechanical stimulusGO:00096121340.012
fatty acid derivative metabolic processGO:1901568380.012
nucleic acid templated transcriptionGO:00976593790.012
positive regulation of neurogenesisGO:00507691650.012
regulation of anatomical structure morphogenesisGO:00226031410.012
regulation of rna metabolic processGO:00512523910.012
phthalate metabolic processGO:001896380.012
positive regulation of cell differentiationGO:00455972170.012
positive regulation of cell projection organizationGO:00313461110.012
negative regulation of response to stimulusGO:00485851550.012
steroid biosynthetic processGO:0006694480.012
response to calcium ionGO:0051592590.012
negative regulation of gene expressionGO:00106291990.012
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.012
cellular sodium ion homeostasisGO:000688340.012
positive regulation of phosphate metabolic processGO:00459372620.012
regulation of fatty acid oxidationGO:0046320100.012
regulation of nucleic acid templated transcriptionGO:19035063800.012
circadian rhythmGO:0007623880.012
response to acetateGO:001003430.012
response to amino acidGO:0043200750.012
regulation of blood vessel sizeGO:0050880890.012
regulation of inflammatory responseGO:0050727480.012
alpha amino acid metabolic processGO:1901605710.012
forebrain developmentGO:0030900980.011
metal ion homeostasisGO:00550651860.011
response to foodGO:0032094270.011
cellular response to growth factor stimulusGO:00713631620.011
monocarboxylic acid biosynthetic processGO:0072330480.011
brain renin angiotensin systemGO:000203530.011
axis specificationGO:000979840.011
positive regulation of programmed cell deathGO:00430681570.011
small gtpase mediated signal transductionGO:0007264360.011
glial cell differentiationGO:0010001650.011
icosanoid metabolic processGO:0006690380.011
cellular response to nitrogen compoundGO:19016992100.011
sulfationGO:005192320.011
cellular response to fatty acidGO:0071398290.011
regulation of defense responseGO:0031347680.011
cation transmembrane transportGO:00986552630.011
artery smooth muscle contractionGO:001482440.011
rna biosynthetic processGO:00327743800.011
response to glucoseGO:00097491360.011
chemosensory behaviorGO:000763520.011
intestinal absorptionGO:005089230.011
very long chain fatty acid metabolic processGO:000003830.011
positive regulation of nitrogen compound metabolic processGO:00511733340.011
purine nucleotide metabolic processGO:00061632290.011
ribonucleotide metabolic processGO:00092592310.011
cellular response to steroid hormone stimulusGO:0071383930.011
positive regulation of transportGO:00510502450.011
rna metabolic processGO:00160704060.011
positive regulation of protein modification processGO:00314011420.011
cellular response to xenobiotic stimulusGO:0071466190.011
sensory perception of painGO:0019233730.011
retinal metabolic processGO:004257430.011
catechol containing compound metabolic processGO:0009712190.011
response to sulfur dioxideGO:001047730.011
lipid storageGO:001991510.011
axonogenesisGO:0007409710.011
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.011
response to monosaccharideGO:00342841590.010
negative regulation of cellular protein metabolic processGO:00322691060.010
pyridine containing compound metabolic processGO:0072524320.010
regulation of kinase activityGO:00435491170.010
positive regulation of cellular biosynthetic processGO:00313282950.010
cellular homeostasisGO:00197252520.010
negative regulation of innate immune responseGO:004582440.010
choline transportGO:001587140.010
muscle cell proliferationGO:0033002840.010
tetrapyrrole metabolic processGO:0033013110.010
cardiovascular system developmentGO:00723581340.010
regulation of endothelial cell apoptotic processGO:200035130.010
negative regulation of protein metabolic processGO:00512481140.010
cell projection organizationGO:00300303020.010
transcription dna templatedGO:00063513770.010
eating behaviorGO:0042755210.010
alpha amino acid biosynthetic processGO:1901607230.010

Hmgcs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.038
disease of metabolismDOID:001466700.038
artery diseaseDOID:005082800.011
vascular diseaseDOID:17800.011
disease of anatomical entityDOID:700.011
cardiovascular system diseaseDOID:128700.011
disease of cellular proliferationDOID:1456600.010