Rattus norvegicus

40 known processes

Kcnh6

potassium voltage-gated channel, subfamily H (eag-related), member 6

(Aliases: Erg2)

Kcnh6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
metal ion transportGO:00300012890.705
cation transportGO:00068123820.331
regulation of ion transportGO:00432692450.324
ion homeostasisGO:00508012120.312
cellular ion homeostasisGO:00068731840.257
regulation of secretion by cellGO:19035302080.229
g protein coupled receptor signaling pathwayGO:00071862420.195
protein complex subunit organizationGO:00718223020.162
cellular metal ion homeostasisGO:00068751720.150
homeostatic processGO:00425923310.149
regulation of metal ion transportGO:00109591180.143
cell cell signalingGO:00072673350.143
synaptic transmissionGO:00072682350.136
calcium ion transportGO:00068161310.134
macromolecular complex subunit organizationGO:00439333390.129
divalent metal ion transportGO:00708381320.122
ion transmembrane transportGO:00342203650.116
behaviorGO:00076102050.115
cytosolic calcium ion homeostasisGO:00514801400.113
response to corticosteroidGO:00319602350.113
neuropeptide signaling pathwayGO:0007218290.112
regulation of secretionGO:00510462240.112
organic hydroxy compound metabolic processGO:19016151150.112
calcium ion importGO:0070509220.112
cellular calcium ion homeostasisGO:00068741600.105
positive regulation of secretionGO:00510471400.102
divalent inorganic cation transportGO:00725111340.097
peristalsisGO:003043220.097
intracellular signal transductionGO:00355563140.094
carbohydrate derivative metabolic processGO:19011353460.093
regulation of ion transmembrane transportGO:00347651210.090
regulation of cellular localizationGO:00603412630.089
secretionGO:00469033070.085
cellular divalent inorganic cation homeostasisGO:00725031620.084
sensory perception of painGO:0019233730.083
ribonucleotide biosynthetic processGO:0009260850.083
cation homeostasisGO:00550801950.080
divalent inorganic cation homeostasisGO:00725071650.077
vesicle mediated transportGO:00161921810.074
feeding behaviorGO:0007631530.070
positive regulation of cell proliferationGO:00082842490.069
response to oxygen levelsGO:00704822650.066
regulation of blood pressureGO:0008217830.066
protein complex assemblyGO:00064612630.064
anatomical structure morphogenesisGO:00096532980.064
positive regulation of catalytic activityGO:00430851840.063
positive regulation of cytosolic calcium ion concentrationGO:00072041220.061
brain developmentGO:00074202470.061
Rat
sensory perceptionGO:00076001010.060
Fly
monovalent inorganic cation transportGO:00156721720.058
cellular component biogenesisGO:00440853680.058
muscle system processGO:00030121150.057
cellular chemical homeostasisGO:00550822470.057
organophosphate metabolic processGO:00196373700.057
calcium ion homeostasisGO:00550741620.057
cellular cation homeostasisGO:00300031800.056
cyclic purine nucleotide metabolic processGO:0052652620.055
inorganic cation transmembrane transportGO:00986622020.055
multicellular organismal signalingGO:0035637440.055
regulation of phosphorus metabolic processGO:00511743490.054
metal ion homeostasisGO:00550651860.053
carbohydrate derivative biosynthetic processGO:19011371240.053
inorganic ion transmembrane transportGO:00986602290.053
mechanoreceptor differentiationGO:004249020.052
ribose phosphate metabolic processGO:00196932350.052
cation transmembrane transportGO:00986552630.051
multi organism reproductive processGO:00447032620.050
regulation of cyclase activityGO:0031279210.050
positive regulation of molecular functionGO:00440932300.049
agingGO:00075682410.049
regulation of defecationGO:200029210.048
smooth muscle contractionGO:0006939370.048
nucleoside phosphate metabolic processGO:00067532830.047
regulation of heart contractionGO:0008016480.047
forebrain developmentGO:0030900980.047
positive regulation of serotonin secretionGO:001406410.047
regulation of phosphate metabolic processGO:00192203490.046
secretion by cellGO:00329402480.045
nitrogen compound transportGO:00717052290.045
transmembrane transportGO:00550854120.045
apoptotic processGO:00069153810.045
Rat
cyclic nucleotide biosynthetic processGO:0009190630.044
muscle contractionGO:0006936880.044
regulation of anatomical structure morphogenesisGO:00226031410.044
cellular homeostasisGO:00197252520.044
purine containing compound metabolic processGO:00725212530.043
head developmentGO:00603222470.043
Rat
negative regulation of metabolic processGO:00098923310.043
defecationGO:003042110.042
gastric inhibitory peptide signaling pathwayGO:003819210.042
amine transportGO:0015837570.042
positive regulation of nucleotide metabolic processGO:0045981910.042
regulation of transmembrane transportGO:00347621220.040
purine nucleotide metabolic processGO:00061632290.040
regulation of neurological system processGO:0031644430.040
single organism carbohydrate metabolic processGO:00447231180.040
single organism behaviorGO:00447081300.040
inflammatory responseGO:00069541500.039
response to mechanical stimulusGO:00096121340.039
cellular component assemblyGO:00226073600.039
regulation of catalytic activityGO:00507903040.039
regulation of homeostatic processGO:00328441010.039
alcohol metabolic processGO:0006066770.038
negative regulation of cellular metabolic processGO:00313242810.038
response to glucocorticoidGO:00513842230.038
positive regulation of secretion by cellGO:19035321280.038
response to bacteriumGO:00096172000.038
neuron differentiationGO:00301823680.038
heart developmentGO:0007507720.037
signal transduction by phosphorylationGO:00230141440.037
ribonucleotide metabolic processGO:00092592310.037
macromolecular complex assemblyGO:00650032730.037
response to woundingGO:00096112540.037
chemical homeostasisGO:00488782920.037
urinary tract smooth muscle contractionGO:001484840.037
regulation of signal transductionGO:00099663180.036
regulation of hormone levelsGO:00108171870.036
regulation of calcium ion transportGO:0051924770.036
cyclic nucleotide metabolic processGO:0009187800.036
potassium ion transmembrane transportGO:0071805710.036
regulation of transporter activityGO:0032409500.035
regulation of cyclic nucleotide metabolic processGO:0030799510.035
heart processGO:0003015570.035
regulation of camp metabolic processGO:0030814430.034
neuron fate commitmentGO:004866340.034
cell type specific apoptotic processGO:00972851340.033
phasic smooth muscle contractionGO:001482130.033
eye morphogenesisGO:004859240.033
purine ribonucleotide biosynthetic processGO:0009152810.033
cellular potassium ion transportGO:0071804720.033
central nervous system developmentGO:00074173110.032
Rat
regulation of cell differentiationGO:00455953200.032
ribonucleoside triphosphate catabolic processGO:00092031220.032
neurological system processGO:00508772190.032
Fly
positive regulation of dopamine secretionGO:003360380.032
cognitionGO:0050890920.032
response to decreased oxygen levelsGO:00362932370.031
regulation of norepinephrine secretionGO:0014061150.031
positive regulation of cellular component organizationGO:00511302000.031
regulation of cyclic nucleotide biosynthetic processGO:0030802450.031
nucleotide metabolic processGO:00091172790.031
negative regulation of follicle stimulating hormone secretionGO:004688230.031
positive regulation of peptide hormone secretionGO:0090277500.030
regulation of lyase activityGO:0051339220.030
protein phosphorylationGO:00064683450.030
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.030
positive regulation of cell deathGO:00109421840.029
response to cocaineGO:0042220390.029
regulation of synaptic transmissionGO:00508041410.029
positive regulation of cyclic nucleotide metabolic processGO:0030801370.028
excretionGO:0007588240.028
nucleobase containing small molecule metabolic processGO:00550863160.028
purine nucleoside metabolic processGO:00422781690.028
axonogenesisGO:0007409710.028
transmission of nerve impulseGO:0019226420.027
camp metabolic processGO:0046058630.027
organic substance catabolic processGO:19015753160.027
catecholamine secretionGO:0050432330.027
regulation of catecholamine secretionGO:0050433320.027
camp biosynthetic processGO:0006171470.027
response to hypoxiaGO:00016662310.027
regulation of intracellular signal transductionGO:19025312180.027
organic hydroxy compound transportGO:0015850770.027
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.027
cellular response to steroid hormone stimulusGO:0071383930.026
positive regulation of hormone secretionGO:0046887650.026
regulation of adenylate cyclase activityGO:0045761180.026
regulation of apoptotic processGO:00429813350.026
Rat
growthGO:00400071650.026
regulation of ion transmembrane transporter activityGO:0032412480.026
response to hydrogen peroxideGO:0042542890.026
cellular response to glucocorticoid stimulusGO:0071385680.026
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.026
positive regulation of cell communicationGO:00106472710.026
regulation of multicellular organismal developmentGO:20000263760.026
organonitrogen compound biosynthetic processGO:19015661670.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.025
calcium mediated signalingGO:0019722230.025
reproductive processGO:00224143720.025
ribose phosphate biosynthetic processGO:0046390870.025
negative regulation of transportGO:00510511360.025
positive regulation of cell differentiationGO:00455972170.025
positive regulation of phosphorus metabolic processGO:00105622620.025
tonic smooth muscle contractionGO:001482040.024
tissue developmentGO:00098882520.024
regulation of axonogenesisGO:0050770370.024
nucleoside phosphate biosynthetic processGO:19012931020.024
norepinephrine secretionGO:0048243160.024
cellular component movementGO:00069282480.024
hair cell differentiationGO:003531520.024
multicellular organism reproductionGO:00325042330.024
anatomical structure formation involved in morphogenesisGO:0048646830.024
regulation of membrane potentialGO:00423911100.024
Rat
regulation of excretionGO:0044062210.024
positive regulation of nitrogen compound metabolic processGO:00511733340.023
response to growth factorGO:00708481890.023
positive regulation of camp biosynthetic processGO:0030819280.023
cytoskeleton organizationGO:00070101110.023
cellular response to nitrogen compoundGO:19016992100.023
response to molecule of bacterial originGO:00022371940.023
response to transition metal nanoparticleGO:19902671220.022
learning or memoryGO:0007611900.022
positive regulation of response to stimulusGO:00485842850.022
cellular response to endogenous stimulusGO:00714953770.022
biological adhesionGO:00226101100.022
regulation of cellular component organizationGO:00511283680.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
peptide secretionGO:0002790860.022
response to nutrient levelsGO:00316673700.022
mapk cascadeGO:00001651400.022
regulation of amine transportGO:0051952540.022
purine ribonucleotide metabolic processGO:00091502270.022
acid secretionGO:0046717480.022
organelle organizationGO:00069962660.022
positive regulation of synaptic transmissionGO:0050806620.022
pancreatic a cell differentiationGO:000331010.022
positive regulation of cell developmentGO:00107201760.021
multi multicellular organism processGO:00447061380.021
artery smooth muscle contractionGO:001482440.021
negative regulation of gene expressionGO:00106291990.021
regulation of follicle stimulating hormone secretionGO:004688050.021
positive regulation of developmental processGO:00510942830.021
positive regulation of hydrolase activityGO:0051345860.021
multicellular organismal response to stressGO:0033555250.021
positive regulation of programmed cell deathGO:00430681570.021
regulation of molecular functionGO:00650093980.021
regulation of anatomical structure sizeGO:00900661350.021
detection of temperature stimulus involved in sensory perception of painGO:005096540.021
positive regulation of heart contractionGO:0045823150.021
positive regulation of camp metabolic processGO:0030816310.020
positive regulation of nervous system developmentGO:00519621780.020
cellular component morphogenesisGO:00329891550.020
positive regulation of transportGO:00510502450.020
second messenger mediated signalingGO:0019932510.020
response to biotic stimulusGO:00096072260.020
positive regulation of intracellular signal transductionGO:19025331380.020
locomotionGO:00400112370.020
purine nucleotide biosynthetic processGO:0006164830.020
regulation of purine nucleotide metabolic processGO:19005421150.020
protein oligomerizationGO:00512591910.020
neuron apoptotic processGO:0051402880.019
carboxylic acid transportGO:00469421150.019
response to fatty acidGO:0070542650.019
positive regulation of catecholamine secretionGO:0033605130.019
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.019
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.019
peptide transportGO:0015833970.019
potassium ion transportGO:0006813970.019
organophosphate biosynthetic processGO:00904071430.019
regulation of neuron deathGO:19012141150.019
actin filament based processGO:0030029860.019
purine nucleotide catabolic processGO:00061951360.019
purine ribonucleoside catabolic processGO:00461301240.019
regulation of neuron differentiationGO:00456642080.018
response to axon injuryGO:0048678590.018
detection of temperature stimulusGO:001604840.018
regulation of system processGO:00440572080.018
positive regulation of cyclase activityGO:0031281150.018
positive regulation of signal transductionGO:00099671750.018
reproductionGO:00000032450.018
response to extracellular stimulusGO:00099913800.018
regulation of cellular amine metabolic processGO:003323880.018
positive regulation of neurogenesisGO:00507691650.018
response to other organismGO:00517072200.018
response to lipopolysaccharideGO:00324961910.018
neuron developmentGO:00486662860.018
hormone mediated signaling pathwayGO:0009755230.018
cell motilityGO:00488702020.018
regulation of nucleotide metabolic processGO:00061401170.017
rhythmic processGO:00485111560.017
Rat
response to foodGO:0032094270.017
response to campGO:0051591910.017
urinary bladder smooth muscle contractionGO:001483240.017
inner ear receptor cell differentiationGO:006011320.017
regulation of cell developmentGO:00602842630.017
regulation of saliva secretionGO:004687730.017
regulation of neurogenesisGO:00507672470.017
cell adhesionGO:00071551100.017
regulation of nervous system developmentGO:00519602640.017
positive regulation of mapk cascadeGO:0043410920.017
development of primary female sexual characteristicsGO:0046545560.017
negative regulation of epinephrine secretionGO:003281160.017
gamete generationGO:00072761240.017
purine containing compound biosynthetic processGO:0072522850.017
cell morphogenesis involved in differentiationGO:00009041190.017
hormone secretionGO:00468791150.017
positive regulation of cellular biosynthetic processGO:00313282950.017
response to ammonium ionGO:0060359710.017
response to nutrientGO:00075842480.016
response to amineGO:0014075460.016
positive regulation of phosphate metabolic processGO:00459372620.016
action potentialGO:0001508540.016
response to nicotineGO:0035094510.016
gastric motilityGO:003548230.016
anterior posterior pattern specificationGO:000995210.016
renal sodium excretionGO:0035812200.016
regulation of hormone secretionGO:00468831060.016
single organism biosynthetic processGO:00447113420.016
negative regulation of defecationGO:200029310.016
amine metabolic processGO:0009308380.016
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.016
positive regulation of saliva secretionGO:004687830.016
response to external biotic stimulusGO:00432072210.016
response to estradiolGO:00323551640.016
neuron projection developmentGO:00311752730.016
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
negative regulation of multicellular organismal processGO:00512412030.015
regulation of cell projection organizationGO:00313441750.015
negative regulation of luteinizing hormone secretionGO:003368540.015
regulation of cell proliferationGO:00421273590.015
cell projection organizationGO:00300303020.015
adult locomotory behaviorGO:000834440.015
ras protein signal transductionGO:0007265290.015
synaptic vesicle amine transportGO:001584230.015
regulation of ion homeostasisGO:2000021630.015
neuron projection morphogenesisGO:00488121220.015
long term synaptic potentiationGO:0060291210.015
signal releaseGO:00230611450.015
alpha amino acid metabolic processGO:1901605710.015
small gtpase mediated signal transductionGO:0007264360.015
regulation of glutamate receptor signaling pathwayGO:1900449170.015
actin cytoskeleton organizationGO:0030036730.015
positive regulation of lyase activityGO:0051349150.015
somatostatin receptor signaling pathwayGO:003816940.015
carbohydrate metabolic processGO:00059751300.015
regulation of synaptic plasticityGO:0048167700.015
regulation of transmembrane transporter activityGO:0022898490.015
single organism intracellular transportGO:19025821660.015
axon developmentGO:0061564960.015
regulation of neuron apoptotic processGO:0043523830.015
cellular response to stressGO:00335542690.014
catecholamine transportGO:0051937370.014
positive regulation of nucleobase containing compound metabolic processGO:00459353190.014
protein complex biogenesisGO:00702712630.014
developmental process involved in reproductionGO:00030061590.014
nucleoside phosphate catabolic processGO:19012921400.014
auditory receptor cell differentiationGO:004249120.014
cellular amine metabolic processGO:0044106380.014
positive regulation of signalingGO:00230562700.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
regulation of cellular protein metabolic processGO:00322682670.014
macromolecule localizationGO:00330362520.014
angiotensin mediated drinking behaviorGO:000305120.014
response to glucoseGO:00097491360.014
regulation of cell morphogenesis involved in differentiationGO:0010769720.014
phototransduction visible lightGO:000760320.014
neuron deathGO:00709971270.014
programmed cell deathGO:00125013920.014
Rat
positive regulation of amine transportGO:0051954260.014
cell substrate adhesionGO:0031589290.014
regulation of cytoskeleton organizationGO:0051493490.014
cell morphogenesisGO:00009021420.014
single organism organelle organizationGO:19025891800.014
nucleobase containing compound catabolic processGO:00346551520.014
regulation of protein modification processGO:00313991940.014
negative regulation of developmental processGO:00510931250.013
response to activityGO:0014823730.013
nucleotide biosynthetic processGO:0009165980.013
hormone metabolic processGO:0042445690.013
negative regulation of molecular functionGO:00440921330.013
smooth muscle cell proliferationGO:0048659770.013
regulation of hydrolase activityGO:00513361430.013
desensitization of g protein coupled receptor protein signaling pathwayGO:0002029100.013
regulation of feeding behaviorGO:0060259140.013
organonitrogen compound catabolic processGO:19015651790.013
positive regulation of purine nucleotide biosynthetic processGO:1900373360.013
glycosyl compound catabolic processGO:19016581260.013
detection of external stimulusGO:0009581130.013
ventral spinal cord developmentGO:002151730.013
rna metabolic processGO:00160704060.013
Rat
multicellular organism growthGO:003526410.013
cellular response to drugGO:0035690300.013
rho protein signal transductionGO:0007266110.013
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
regulation of transferase activityGO:00513381230.013
organic anion transportGO:00157111320.013
axis specificationGO:000979840.013
hormone transportGO:00099141210.013
negative regulation of signalingGO:00230571570.012
cellular response to lipidGO:00713962010.012
transcription from rna polymerase ii promoterGO:00063662520.012
Rat
regulation of blood circulationGO:19035221100.012
cell fate determinationGO:000170920.012
positive regulation of heart rateGO:001046090.012
calcium ion transmembrane transportGO:0070588700.012
cardiovascular system developmentGO:00723581340.012
cell projection morphogenesisGO:00488581230.012
response to purine containing compoundGO:00140741260.012
transcription dna templatedGO:00063513770.012
Rat
spermatogenesisGO:0007283990.012
response to herbicideGO:0009635160.012
positive regulation of apoptotic processGO:00430651540.012
sodium ion transportGO:0006814820.012
ribonucleoside catabolic processGO:00424541260.012
heart contractionGO:0060047570.012
visual perceptionGO:000760130.012
positive regulation of adenylate cyclase activityGO:0045762120.012
blood circulationGO:00080151830.012
cellular response to growth factor stimulusGO:00713631620.012
proteolysisGO:00065081750.012
negative regulation of calcium ion importGO:009028120.011
regulation of transcription dna templatedGO:00063553740.011
Rat
negative regulation of ion transportGO:0043271510.011
response to radiationGO:00093141370.011
response to metal ionGO:00100382530.011
muscle cell proliferationGO:0033002840.011
regulation of nucleic acid templated transcriptionGO:19035063800.011
Rat
negative regulation of g protein coupled receptor protein signaling pathwayGO:0045744150.011
regulation of muscle system processGO:0090257790.011
learningGO:0007612330.011
male gamete generationGO:0048232990.011
single organism catabolic processGO:00447122830.011
ribonucleoside metabolic processGO:00091191740.011
negative regulation of transcription dna templatedGO:00458921160.011
ribonucleotide catabolic processGO:00092611360.011
involuntary skeletal muscle contractionGO:000301120.011
cellular nitrogen compound catabolic processGO:00442701630.011
monoamine transportGO:0015844430.011
regulation of vesicle mediated transportGO:0060627810.011
cellular carbohydrate metabolic processGO:0044262720.011
cellular protein localizationGO:00346131220.011
sensory perception of light stimulusGO:005095330.011
regulation of protein metabolic processGO:00512462890.011
cellular response to corticosteroid stimulusGO:0071384690.011
cellular catabolic processGO:00442482950.011
regulation of nucleotide biosynthetic processGO:0030808470.011
positive regulation of peptide secretionGO:0002793520.011
rna biosynthetic processGO:00327743800.011
Rat
memoryGO:0007613540.011
cellular response to inorganic substanceGO:0071241650.011
positive regulation of blood circulationGO:1903524650.011
organic hydroxy compound biosynthetic processGO:1901617510.011
regulation of notch signaling pathwayGO:000859330.010
female pregnancyGO:00075651220.010
positive regulation of appetiteGO:003210020.010
positive regulation of transferase activityGO:0051347810.010
neuron fate specificationGO:004866530.010
negative regulation of multicellular organismal metabolic processGO:004425240.010
regulation of camp biosynthetic processGO:0030817380.010
response to lead ionGO:0010288330.010
saliva secretionGO:004654130.010
negative regulation of cell proliferationGO:00082851190.010
regulation of response to foodGO:0032095110.010
cartilage development involved in endochondral bone morphogenesisGO:006035130.010
intracellular transportGO:00469071850.010
digestive system developmentGO:0055123410.010
regulation of cell growthGO:0001558850.010
cgmp biosynthetic processGO:0006182150.010
cell migrationGO:00164771970.010
actin filament organizationGO:0007015420.010
cellular response to mechanical stimulusGO:0071260480.010

Kcnh6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinal diseaseDOID:567900.118
disease of anatomical entityDOID:700.118
sensory system diseaseDOID:005015500.118
eye and adnexa diseaseDOID:149200.118
nervous system diseaseDOID:86300.118
eye diseaseDOID:561400.118
retinal degenerationDOID:846600.118
retinitis pigmentosaDOID:1058400.041