Rattus norvegicus

92 known processes

Sik1

salt-inducible kinase 1

(Aliases: Sik,Snf1lk)

Sik1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription from rna polymerase ii promoterGO:00063662520.193
regulation of rna metabolic processGO:00512523910.143
regulation of rna biosynthetic processGO:20011413810.135
regulation of transcription dna templatedGO:00063553740.122
regulation of nucleic acid templated transcriptionGO:19035063800.121
negative regulation of cellular biosynthetic processGO:00313271610.115
rna metabolic processGO:00160704060.110
negative regulation of metabolic processGO:00098923310.108
response to inorganic substanceGO:00100353770.100
cellular response to stressGO:00335542690.089
negative regulation of macromolecule metabolic processGO:00106052600.085
anatomical structure morphogenesisGO:00096532980.084
negative regulation of apoptotic processGO:00430661810.081
rna biosynthetic processGO:00327743800.079
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.079
transcription dna templatedGO:00063513770.077
positive regulation of biosynthetic processGO:00098913190.074
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.072
response to campGO:0051591910.067
negative regulation of gene expressionGO:00106291990.066
negative regulation of macromolecule biosynthetic processGO:00105581480.065
nucleic acid templated transcriptionGO:00976593790.063
regulation of apoptotic processGO:00429813350.061
Human
neuron differentiationGO:00301823680.060
positive regulation of nitrogen compound metabolic processGO:00511733340.060
negative regulation of nucleobase containing compound metabolic processGO:00459341530.060
negative regulation of transcription dna templatedGO:00458921160.060
positive regulation of nucleic acid templated transcriptionGO:19035081970.058
regulation of transcription from rna polymerase ii promoterGO:00063572340.057
negative regulation of cellular metabolic processGO:00313242810.056
tissue developmentGO:00098882520.055
Mouse
regulation of cellular protein metabolic processGO:00322682670.055
response to growth factorGO:00708481890.054
Worm
positive regulation of cellular biosynthetic processGO:00313282950.053
negative regulation of rna metabolic processGO:00512531230.053
carbohydrate derivative metabolic processGO:19011353460.052
positive regulation of rna metabolic processGO:00512542030.051
positive regulation of nucleobase containing compound metabolic processGO:00459353190.051
oxoacid metabolic processGO:00434362900.051
organic acid metabolic processGO:00060822920.051
negative regulation of signalingGO:00230571570.050
organonitrogen compound biosynthetic processGO:19015661670.047
sodium ion transportGO:0006814820.045
carboxylic acid metabolic processGO:00197522890.045
catabolic processGO:00090563510.045
histone h3 acetylationGO:004396620.044
response to oxidative stressGO:00069791860.043
organic substance catabolic processGO:19015753160.041
apoptotic processGO:00069153810.041
Human Mouse
positive regulation of gene expressionGO:00106282440.040
organelle organizationGO:00069962660.040
Rat
positive regulation of macromolecule biosynthetic processGO:00105572470.039
positive regulation of multicellular organismal processGO:00512403870.039
Worm
regulation of phosphorus metabolic processGO:00511743490.039
cellular ketone metabolic processGO:0042180510.038
Mouse
negative regulation of rna biosynthetic processGO:19026791180.037
cellular amino acid metabolic processGO:00065201070.036
response to peptide hormoneGO:00434342780.036
response to peptideGO:19016522920.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.035
regulation of molecular functionGO:00650093980.034
Mouse
negative regulation of protein metabolic processGO:00512481140.034
cellular response to endogenous stimulusGO:00714953770.032
Worm
programmed cell deathGO:00125013920.032
Human Mouse
regulation of protein metabolic processGO:00512462890.032
cellular response to growth factor stimulusGO:00713631620.031
Worm
cellular response to transforming growth factor beta stimulusGO:0071560410.031
Worm
negative regulation of cell communicationGO:00106481580.031
single organism biosynthetic processGO:00447113420.031
Mouse
cellular response to hormone stimulusGO:00328702470.030
cation transportGO:00068123820.030
neuron developmentGO:00486662860.029
response to metal ionGO:00100382530.029
amine metabolic processGO:0009308380.029
nucleobase containing small molecule metabolic processGO:00550863160.029
organophosphate metabolic processGO:00196373700.028
regulation of cell differentiationGO:00455953200.028
Mouse
neuron projection developmentGO:00311752730.028
entrainment of circadian clockGO:000964930.028
Mouse
chemical homeostasisGO:00488782920.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
regulation of cellular component organizationGO:00511283680.028
Rat
positive regulation of rna biosynthetic processGO:19026801970.028
organic cyclic compound catabolic processGO:19013611750.027
central nervous system developmentGO:00074173110.027
regulation of nervous system developmentGO:00519602640.027
cellular homeostasisGO:00197252520.027
regulation of phosphorylationGO:00423252480.027
negative regulation of developmental processGO:00510931250.027
response to hydrogen peroxideGO:0042542890.027
response to purine containing compoundGO:00140741260.026
response to organophosphorusGO:00466831020.026
regulation of cell proliferationGO:00421273590.026
inactivation of mapk activityGO:000018820.026
macromolecular complex subunit organizationGO:00439333390.026
regulation of signal transductionGO:00099663180.026
regulation of multicellular organismal developmentGO:20000263760.026
negative regulation of nucleic acid templated transcriptionGO:19035071170.025
cellular catabolic processGO:00442482950.025
positive regulation of cell proliferationGO:00082842490.025
cellular amine metabolic processGO:0044106380.024
cell projection organizationGO:00300303020.024
protein maturationGO:0051604680.024
regulation of intracellular signal transductionGO:19025312180.024
negative regulation of cell deathGO:00605482290.024
cell part morphogenesisGO:00329901230.024
organic acid biosynthetic processGO:0016053830.024
regulation of cell projection organizationGO:00313441750.023
brain developmentGO:00074202470.023
organic anion transportGO:00157111320.023
response to other organismGO:00517072200.023
regulation of cellular amine metabolic processGO:003323880.023
protein processingGO:0016485680.022
cellular response to lipidGO:00713962010.022
agingGO:00075682410.022
response to bacteriumGO:00096172000.022
nucleobase containing compound catabolic processGO:00346551520.022
negative regulation of biosynthetic processGO:00098901680.021
cellular component movementGO:00069282480.021
Rat
regulation of cellular amino acid metabolic processGO:000652120.021
single organism catabolic processGO:00447122830.021
anion transportGO:00068201780.021
regulation of cytokine productionGO:0001817560.021
nitrogen compound transportGO:00717052290.021
reproductive processGO:00224143720.021
defense responseGO:00069521940.020
chromatin organizationGO:0006325340.020
positive regulation of cellular component organizationGO:00511302000.020
single organism organelle organizationGO:19025891800.020
Rat
proteolysisGO:00065081750.020
regulation of catalytic activityGO:00507903040.020
purine containing compound metabolic processGO:00725212530.020
nucleoside metabolic processGO:00091161790.020
response to estradiolGO:00323551640.019
regulation of neuron projection developmentGO:00109751610.019
lipid metabolic processGO:00066292830.019
Mouse
intracellular signal transductionGO:00355563140.019
Human Mouse Rat
gland developmentGO:00487321550.019
cellular ion homeostasisGO:00068731840.019
cellular cation homeostasisGO:00300031800.019
purine nucleotide metabolic processGO:00061632290.018
photoperiodismGO:000964840.018
Mouse
cellular response to organic cyclic compoundGO:00714072020.018
cytokine productionGO:0001816610.018
cation transmembrane transportGO:00986552630.018
head developmentGO:00603222470.018
metal ion homeostasisGO:00550651860.018
cell motilityGO:00488702020.018
Rat
circadian regulation of gene expressionGO:003292230.018
negative regulation of programmed cell deathGO:00430691830.018
ribose phosphate metabolic processGO:00196932350.018
regulation of cellular ketone metabolic processGO:0010565270.018
Mouse
neurological system processGO:00508772190.018
Worm
negative regulation of cellular protein metabolic processGO:00322691060.018
cell cell signalingGO:00072673350.018
negative regulation of signal transductionGO:0009968830.018
positive regulation of molecular functionGO:00440932300.017
response to light stimulusGO:0009416520.017
Mouse
response to external biotic stimulusGO:00432072210.017
response to hypoxiaGO:00016662310.017
response to ketoneGO:19016541820.017
positive regulation of apoptotic processGO:00430651540.017
Human
response to toxic substanceGO:00096361330.017
regulation of mapk cascadeGO:00434081160.017
macromolecular complex assemblyGO:00650032730.017
response to estrogenGO:00436272320.017
response to nutrient levelsGO:00316673700.017
regulation of programmed cell deathGO:00430673410.017
Human
positive regulation of catalytic activityGO:00430851840.017
positive regulation of programmed cell deathGO:00430681570.017
Human
regulation of anatomical structure morphogenesisGO:00226031410.016
multicellular organism reproductionGO:00325042330.016
response to glucocorticoidGO:00513842230.016
positive regulation of transcription dna templatedGO:00458931970.016
nucleotide metabolic processGO:00091172790.016
response to decreased oxygen levelsGO:00362932370.016
organonitrogen compound catabolic processGO:19015651790.016
axon developmentGO:0061564960.016
cellular response to cytokine stimulusGO:00713451270.016
positive regulation of neurogenesisGO:00507691650.016
protein complex subunit organizationGO:00718223020.016
response to cytokineGO:00340972150.016
mapk cascadeGO:00001651400.016
ion homeostasisGO:00508012120.016
regulation of cell developmentGO:00602842630.015
purine ribonucleotide metabolic processGO:00091502270.015
positive regulation of developmental processGO:00510942830.015
Worm
peptidyl amino acid modificationGO:00181931260.015
dna metabolic processGO:0006259960.015
organic acid transportGO:00158491160.015
heterocycle catabolic processGO:00467001670.015
nucleoside phosphate metabolic processGO:00067532830.015
response to reactive oxygen speciesGO:00003021200.015
positive regulation of cell projection organizationGO:00313461110.015
purine nucleotide catabolic processGO:00061951360.015
cellular response to follicle stimulating hormone stimulusGO:0071372130.015
cellular chemical homeostasisGO:00550822470.015
response to oxygen levelsGO:00704822650.015
localization of cellGO:00516742020.015
Rat
negative regulation of multicellular organismal processGO:00512412030.015
positive regulation of neuron projection developmentGO:0010976990.014
sensory organ developmentGO:0007423740.014
response to calcium ionGO:0051592590.014
aromatic compound catabolic processGO:00194391680.014
alpha amino acid metabolic processGO:1901605710.014
cellular response to oxygen containing compoundGO:19017013860.014
regulation of muscle system processGO:0090257790.014
cellular component morphogenesisGO:00329891550.014
positive regulation of neuron differentiationGO:00456661260.014
ion transmembrane transportGO:00342203650.014
bmp signaling pathwayGO:003050940.014
cytokine biosynthetic processGO:004208930.014
cellular component biogenesisGO:00440853680.014
anterior posterior pattern specificationGO:000995210.014
multicellular organism growthGO:003526410.014
Worm
response to extracellular stimulusGO:00099913800.014
regulation of response to stressGO:00801341260.014
locomotionGO:00400112370.014
Rat
regulation of phosphate metabolic processGO:00192203490.014
regulation of metal ion transportGO:00109591180.014
regulation of system processGO:00440572080.014
cellular nitrogen compound catabolic processGO:00442701630.014
developmental growthGO:00485891000.014
Worm
posttranscriptional regulation of gene expressionGO:0010608370.013
regulation of cellular catabolic processGO:00313291010.013
negative regulation of catalytic activityGO:00430861030.013
cell migrationGO:00164771970.013
Rat
carbohydrate derivative biosynthetic processGO:19011371240.013
cellular response to peptideGO:19016531330.013
mesoderm developmentGO:000749820.013
cell projection morphogenesisGO:00488581230.013
reactive oxygen species biosynthetic processGO:190340980.013
cell morphogenesis involved in differentiationGO:00009041190.013
regulation of neurogenesisGO:00507672470.013
regulation of dendrite developmentGO:0050773590.013
cellular response to fluid shear stressGO:007149840.013
ras protein signal transductionGO:0007265290.013
positive regulation of cellular amine metabolic processGO:003324030.013
organ regenerationGO:00311001010.013
inner ear morphogenesisGO:004247210.013
negative regulation of phosphorus metabolic processGO:0010563800.013
gastrulationGO:000736920.013
cellular component assemblyGO:00226073600.013
homeostatic processGO:00425923310.013
reactive nitrogen species metabolic processGO:200105710.013
oxidation reduction processGO:00551143040.013
cellular metal ion homeostasisGO:00068751720.013
regulation of sodium ion transportGO:0002028210.013
neuron deathGO:00709971270.012
embryonic skeletal system morphogenesisGO:004870430.012
axis specificationGO:000979840.012
purine containing compound biosynthetic processGO:0072522850.012
metal ion transportGO:00300012890.012
positive regulation of cell deathGO:00109421840.012
Human
cation homeostasisGO:00550801950.012
establishment of protein localizationGO:00451841410.012
cell type specific apoptotic processGO:00972851340.012
regulation of blood pressureGO:0008217830.012
macromolecule localizationGO:00330362520.012
response to testosteroneGO:0033574550.012
rhythmic processGO:00485111560.012
Mouse
regulation of neuron differentiationGO:00456642080.012
positive regulation of cell differentiationGO:00455972170.012
negative regulation of response to stimulusGO:00485851550.012
regulation of protein processingGO:0070613500.012
regulation of cellular response to stressGO:0080135490.012
negative regulation of molecular functionGO:00440921330.012
Mouse
positive regulation of phosphate metabolic processGO:00459372620.012
reactive oxygen species metabolic processGO:0072593370.012
cellular response to organonitrogen compoundGO:00714171970.012
response to alkaloidGO:00432791320.012
male gamete generationGO:0048232990.012
cellular response to molecule of bacterial originGO:0071219560.012
carboxylic acid biosynthetic processGO:0046394830.012
blood circulationGO:00080151830.012
muscle system processGO:00030121150.012
regulation of dna metabolic processGO:0051052600.012
positive regulation of cell developmentGO:00107201760.012
organophosphate biosynthetic processGO:00904071430.011
response to molecule of bacterial originGO:00022371940.011
synaptic transmissionGO:00072682350.011
signal transduction by phosphorylationGO:00230141440.011
multicellular organismal reproductive processGO:00486092330.011
negative regulation of protein maturationGO:1903318470.011
ribonucleoside metabolic processGO:00091191740.011
regulation of protein maturationGO:1903317500.011
carbohydrate derivative catabolic processGO:19011361470.011
regulation of nucleotide metabolic processGO:00061401170.011
cell morphogenesis involved in neuron differentiationGO:00486671060.011
lipid localizationGO:0010876620.011
reproductionGO:00000032450.011
Worm
cellular response to gonadotropin stimulusGO:0071371170.011
cellular lipid metabolic processGO:00442552080.011
Mouse
glycosyl compound metabolic processGO:19016571820.011
divalent inorganic cation homeostasisGO:00725071650.011
regulation of purine nucleotide metabolic processGO:19005421150.011
gamete generationGO:00072761240.011
small molecule biosynthetic processGO:00442831240.011
chromatin modificationGO:0016568330.011
spermatogenesisGO:0007283990.011
carbohydrate metabolic processGO:00059751300.011
Mouse
cellular divalent inorganic cation homeostasisGO:00725031620.011
erythrocyte differentiationGO:003021810.011
response to mechanical stimulusGO:00096121340.011
regulation of membrane potentialGO:00423911100.011
response to hexoseGO:00097461440.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
response to retinoic acidGO:0032526630.011
negative regulation of neuron apoptotic processGO:0043524450.010
cellular amino acid biosynthetic processGO:0008652320.010
respiratory gaseous exchangeGO:000758540.010
regulation of neuron apoptotic processGO:0043523830.010
positive regulation of cellular protein metabolic processGO:00322701670.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
epithelium developmentGO:0060429960.010
cell morphogenesisGO:00009021420.010
neuron projection morphogenesisGO:00488121220.010
endocytosisGO:0006897840.010
positive regulation of biomineral tissue developmentGO:007016940.010
regulation of transferase activityGO:00513381230.010
positive regulation of nervous system developmentGO:00519621780.010
small gtpase mediated signal transductionGO:0007264360.010
chromosome organizationGO:0051276360.010
regulation of reactive oxygen species metabolic processGO:2000377260.010

Sik1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
cardiovascular system diseaseDOID:128700.013
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
organ system cancerDOID:005068600.013
disease of metabolismDOID:001466700.010