Rattus norvegicus

16 known processes

Chm

choroideremia (Rab escort protein 1)

Chm biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex subunit organizationGO:00439333390.145
neuron developmentGO:00486662860.129
muscle system processGO:00030121150.107
cellular component biogenesisGO:00440853680.094
carbohydrate derivative metabolic processGO:19011353460.084
transcription dna templatedGO:00063513770.082
defecationGO:003042110.081
cellular component assemblyGO:00226073600.080
synaptic transmissionGO:00072682350.076
rhythmic processGO:00485111560.076
organic acid metabolic processGO:00060822920.075
carbohydrate metabolic processGO:00059751300.073
circadian rhythmGO:0007623880.073
single organism biosynthetic processGO:00447113420.072
cellular component morphogenesisGO:00329891550.069
nucleobase containing small molecule metabolic processGO:00550863160.063
protein complex subunit organizationGO:00718223020.062
cell projection organizationGO:00300303020.062
neuron projection morphogenesisGO:00488121220.061
chemical homeostasisGO:00488782920.060
protein complex assemblyGO:00064612630.059
ribonucleotide metabolic processGO:00092592310.058
neuron differentiationGO:00301823680.057
negative regulation of macromolecule metabolic processGO:00106052600.056
cell projection morphogenesisGO:00488581230.055
protein complex biogenesisGO:00702712630.052
nucleic acid templated transcriptionGO:00976593790.052
oxoacid metabolic processGO:00434362900.052
inorganic ion transmembrane transportGO:00986602290.051
organophosphate metabolic processGO:00196373700.050
nucleoside phosphate metabolic processGO:00067532830.050
regulation of nucleic acid templated transcriptionGO:19035063800.050
cell cell signalingGO:00072673350.050
reproductionGO:00000032450.049
response to metal ionGO:00100382530.048
synaptic vesicle exocytosisGO:0016079150.048
maintenance of locationGO:0051235170.047
carboxylic acid metabolic processGO:00197522890.047
regulation of transcription dna templatedGO:00063553740.046
purine nucleotide metabolic processGO:00061632290.046
regulation of catalytic activityGO:00507903040.045
reproductive processGO:00224143720.044
rna metabolic processGO:00160704060.043
homeostatic processGO:00425923310.043
neuron projection developmentGO:00311752730.042
organelle localizationGO:0051640550.042
cell part morphogenesisGO:00329901230.042
negative regulation of metabolic processGO:00098923310.041
programmed cell deathGO:00125013920.040
purine ribonucleotide metabolic processGO:00091502270.040
protein oligomerizationGO:00512591910.039
transmembrane transportGO:00550854120.039
cellular response to nitrogen compoundGO:19016992100.039
protein phosphorylationGO:00064683450.039
protein homooligomerizationGO:0051260910.038
nucleotide metabolic processGO:00091172790.038
response to hypoxiaGO:00016662310.038
negative regulation of nitrogen compound metabolic processGO:00511721610.038
cation homeostasisGO:00550801950.038
cellular response to corticosteroid stimulusGO:0071384690.037
response to glucocorticoidGO:00513842230.037
negative regulation of apoptotic processGO:00430661810.037
cell morphogenesis involved in differentiationGO:00009041190.037
apoptotic processGO:00069153810.036
sequestering of metal ionGO:005123890.036
anterior posterior pattern specificationGO:000995210.036
catabolic processGO:00090563510.035
negative regulation of cellular metabolic processGO:00313242810.035
cation transmembrane transportGO:00986552630.035
actin mediated cell contractionGO:0070252120.035
protein heterooligomerizationGO:0051291890.034
axis specificationGO:000979840.034
tissue developmentGO:00098882520.034
spindle organizationGO:000705120.033
heart processGO:0003015570.033
secretionGO:00469033070.033
cell cycleGO:00070491010.033
single organism organelle organizationGO:19025891800.032
macromolecular complex assemblyGO:00650032730.032
regulation of cellular protein metabolic processGO:00322682670.032
epithelium developmentGO:0060429960.032
organonitrogen compound biosynthetic processGO:19015661670.032
regulation of phosphorylationGO:00423252480.032
inorganic cation transmembrane transportGO:00986622020.031
regulation of ion transportGO:00432692450.031
cyclic nucleotide metabolic processGO:0009187800.031
cellular chemical homeostasisGO:00550822470.031
synaptic growth at neuromuscular junctionGO:005112410.031
response to extracellular stimulusGO:00099913800.031
sequestering of calcium ionGO:005120880.031
regulation of phosphate metabolic processGO:00192203490.030
ribose phosphate metabolic processGO:00196932350.030
purine containing compound metabolic processGO:00725212530.030
actin filament based processGO:0030029860.030
developmental growthGO:00485891000.030
cellular response to organonitrogen compoundGO:00714171970.029
regulation of cellular component organizationGO:00511283680.029
response to corticosteroidGO:00319602350.029
cellular homeostasisGO:00197252520.029
multicellular organismal reproductive processGO:00486092330.029
metal ion homeostasisGO:00550651860.029
central nervous system developmentGO:00074173110.029
single organism carbohydrate metabolic processGO:00447231180.029
non canonical wnt signaling pathwayGO:003556730.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
regulation of protein metabolic processGO:00512462890.029
response to inorganic substanceGO:00100353770.028
transcription from rna polymerase ii promoterGO:00063662520.028
neurological system processGO:00508772190.027
developmental process involved in reproductionGO:00030061590.027
protein localizationGO:00081041910.027
Human
response to peptideGO:19016522920.027
synapse organizationGO:0050808460.027
heart morphogenesisGO:000300730.027
single organism intracellular transportGO:19025821660.027
Human
cardiac muscle cell contractionGO:0086003100.027
single organism reproductive processGO:00447022970.026
locomotor rhythmGO:004547510.026
blood circulationGO:00080151830.026
response to nutrient levelsGO:00316673700.026
negative regulation of phosphorus metabolic processGO:0010563800.026
cyclic nucleotide biosynthetic processGO:0009190630.026
organophosphate biosynthetic processGO:00904071430.026
cellular metal ion homeostasisGO:00068751720.026
regulation of phosphorus metabolic processGO:00511743490.026
regulation of transcription from rna polymerase ii promoterGO:00063572340.026
lipid metabolic processGO:00066292830.025
response to carbohydrateGO:00097431830.025
cytoplasmic transportGO:00164821150.025
multi organism reproductive processGO:00447032620.025
regulation of ion transmembrane transportGO:00347651210.025
actin filament based movementGO:0030048160.025
cellular component movementGO:00069282480.025
cellular ion homeostasisGO:00068731840.025
cation transportGO:00068123820.025
ion homeostasisGO:00508012120.025
nucleoside phosphate biosynthetic processGO:19012931020.024
positive regulation of biosynthetic processGO:00098913190.024
carbohydrate derivative biosynthetic processGO:19011371240.024
regulation of cell proliferationGO:00421273590.024
macromolecule localizationGO:00330362520.024
Human
regulation of purine nucleotide metabolic processGO:19005421150.024
cellular catabolic processGO:00442482950.023
multicellular organism reproductionGO:00325042330.023
cellular response to glucocorticoid stimulusGO:0071385680.023
negative regulation of cell proliferationGO:00082851190.023
g protein coupled receptor signaling pathwayGO:00071862420.023
response to oxygen levelsGO:00704822650.023
positive regulation of rna metabolic processGO:00512542030.023
vesicle mediated transportGO:00161921810.023
regulation of membrane potentialGO:00423911100.023
negative regulation of signalingGO:00230571570.023
ribonucleotide catabolic processGO:00092611360.022
cell morphogenesis involved in neuron differentiationGO:00486671060.022
cell morphogenesisGO:00009021420.022
circulatory system processGO:00030131830.022
prostaglandin secretionGO:003231060.022
cellular ketone metabolic processGO:0042180510.022
anatomical structure morphogenesisGO:00096532980.022
regulation of molecular functionGO:00650093980.022
positive regulation of cellular biosynthetic processGO:00313282950.022
cellular calcium ion homeostasisGO:00068741600.022
cellular protein localizationGO:00346131220.022
Human
cellular response to organic cyclic compoundGO:00714072020.022
regulation of ion transmembrane transporter activityGO:0032412480.022
small molecule biosynthetic processGO:00442831240.021
regulation of protein serine threonine kinase activityGO:0071900640.021
positive regulation of transcription dna templatedGO:00458931970.021
mesoderm developmentGO:000749820.021
cellular response to endogenous stimulusGO:00714953770.021
ribonucleotide biosynthetic processGO:0009260850.021
cellular response to oxygen containing compoundGO:19017013860.021
regulation of anatomical structure sizeGO:00900661350.021
cytoskeleton organizationGO:00070101110.021
intracellular transportGO:00469071850.021
Human
response to peptide hormoneGO:00434342780.021
exocytosisGO:0006887600.021
response to glucoseGO:00097491360.021
purine containing compound biosynthetic processGO:0072522850.021
neuron neuron synaptic transmissionGO:0007270600.021
purine nucleotide biosynthetic processGO:0006164830.021
synaptic transmission glycinergicGO:006001220.021
growthGO:00400071650.020
nucleotide biosynthetic processGO:0009165980.020
response to monosaccharideGO:00342841590.020
nucleobase containing compound catabolic processGO:00346551520.020
negative regulation of biosynthetic processGO:00098901680.020
regulation of synaptic growth at neuromuscular junctionGO:000858210.020
regulation of epithelial cell differentiationGO:0030856120.019
cellular response to peptide hormone stimulusGO:00713751200.019
neurotransmitter secretionGO:0007269330.019
mesoderm morphogenesisGO:004833210.019
exploration behaviorGO:003564010.019
ion transmembrane transportGO:00342203650.019
cellular response to growth factor stimulusGO:00713631620.019
response to ketoneGO:19016541820.019
organ morphogenesisGO:0009887750.019
gastrulationGO:000736920.019
monocarboxylic acid metabolic processGO:00327871520.019
regulation of transporter activityGO:0032409500.019
organic cyclic compound catabolic processGO:19013611750.019
divalent inorganic cation homeostasisGO:00725071650.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
organelle organizationGO:00069962660.019
response to calcium ionGO:0051592590.019
intracellular signal transductionGO:00355563140.019
embryonic pattern specificationGO:000988010.019
monosaccharide metabolic processGO:0005996610.019
negative regulation of gene expressionGO:00106291990.019
positive regulation of nitrogen compound metabolic processGO:00511733340.018
regulation of cellular localizationGO:00603412630.018
sexual reproductionGO:00199531480.018
response to alkaloidGO:00432791320.018
positive regulation of cellular component organizationGO:00511302000.018
asymmetric protein localizationGO:000810520.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
regulation of nucleotide metabolic processGO:00061401170.018
cellular response to lipidGO:00713962010.018
regulation of homeostatic processGO:00328441010.018
positive regulation of macromolecule biosynthetic processGO:00105572470.018
cellular response to peptideGO:19016531330.018
response to hexoseGO:00097461440.018
heterocycle catabolic processGO:00467001670.018
cellular response to steroid hormone stimulusGO:0071383930.018
transmission of nerve impulseGO:0019226420.018
single organism catabolic processGO:00447122830.018
positive regulation of biomineral tissue developmentGO:007016940.018
response to radiationGO:00093141370.017
camp metabolic processGO:0046058630.017
calcium ion homeostasisGO:00550741620.017
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.017
positive regulation of ion transportGO:0043270940.017
prostaglandin transportGO:001573280.017
formation of primary germ layerGO:000170410.017
regulation of rna metabolic processGO:00512523910.017
positive regulation of gene expressionGO:00106282440.017
synaptic vesicle endocytosisGO:004848840.017
small gtpase mediated signal transductionGO:0007264360.017
positive regulation of cytoskeleton organizationGO:0051495260.017
positive regulation of transforming growth factor beta3 productionGO:003291620.016
negative regulation of rna biosynthetic processGO:19026791180.016
tube formationGO:003514830.016
negative regulation of cellular biosynthetic processGO:00313271610.016
organic substance catabolic processGO:19015753160.016
positive regulation of apoptotic processGO:00430651540.016
regulation of programmed cell deathGO:00430673410.016
response to nutrientGO:00075842480.016
regulation of protein modification processGO:00313991940.016
anion transportGO:00068201780.016
glycosyl compound metabolic processGO:19016571820.016
negative regulation of cell communicationGO:00106481580.016
regulation of transmembrane transportGO:00347621220.016
axonogenesisGO:0007409710.016
striated muscle contractionGO:0006941440.016
mitotic cell cycleGO:0000278490.016
positive regulation of cell deathGO:00109421840.016
nucleoside triphosphate metabolic processGO:00091411440.015
positive regulation of fatty acid transportGO:200019390.015
axon developmentGO:0061564960.015
activation of cysteine type endopeptidase activityGO:009720240.015
regulation of rna biosynthetic processGO:20011413810.015
purine containing compound catabolic processGO:00725231380.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
second messenger mediated signalingGO:0019932510.015
cytoskeleton dependent cytokinesisGO:006164020.015
response to cytokineGO:00340972150.015
regulation of cell developmentGO:00602842630.015
response to decreased oxygen levelsGO:00362932370.015
multicellular organism growthGO:003526410.015
cellular response to hormone stimulusGO:00328702470.015
cell cycle processGO:0022402570.015
regulation of purine nucleotide biosynthetic processGO:1900371460.015
regulation of cellular component sizeGO:0032535510.015
organonitrogen compound catabolic processGO:19015651790.014
ras protein signal transductionGO:0007265290.014
action potentialGO:0001508540.014
male mating behaviorGO:006017930.014
positive regulation of cell proliferationGO:00082842490.014
aromatic compound catabolic processGO:00194391680.014
negative regulation of cellular protein metabolic processGO:00322691060.014
cyclic purine nucleotide metabolic processGO:0052652620.014
cytosolic calcium ion homeostasisGO:00514801400.014
response to toxic substanceGO:00096361330.014
regulation of signal transductionGO:00099663180.014
cell adhesionGO:00071551100.014
embryonic skeletal system developmentGO:004870630.014
actin cytoskeleton organizationGO:0030036730.014
regulation of cellular component biogenesisGO:0044087860.014
purine ribonucleotide catabolic processGO:00091541360.014
positive regulation of cellular component biogenesisGO:0044089550.014
regulation of protein phosphorylationGO:00019321830.014
cellular cation homeostasisGO:00300031800.014
metal ion transportGO:00300012890.014
regulation of secretion by cellGO:19035302080.014
gamete generationGO:00072761240.014
brain developmentGO:00074202470.014
regulation of cyclic nucleotide metabolic processGO:0030799510.014
negative regulation of cell deathGO:00605482290.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
establishment of protein localizationGO:00451841410.013
Human
mitotic spindle organizationGO:000705220.013
secretion by cellGO:00329402480.013
reproductive structure developmentGO:00486081280.013
cardiovascular system developmentGO:00723581340.013
purine ribonucleoside metabolic processGO:00461281680.013
regulation of organelle organizationGO:0033043800.013
positive regulation of molecular functionGO:00440932300.013
positive regulation of bone mineralizationGO:003050140.013
regulation of hormone levelsGO:00108171870.013
camp biosynthetic processGO:0006171470.013
regulation of growthGO:00400081050.013
purine nucleoside triphosphate metabolic processGO:00091441410.013
purine ribonucleotide biosynthetic processGO:0009152810.013
regulation of cellular response to stressGO:0080135490.013
endoplasmic reticulum to cytosol transportGO:190351340.013
embryonic axis specificationGO:000057810.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
cellular macromolecular complex assemblyGO:0034622580.013
nitrogen compound transportGO:00717052290.013
ribose phosphate biosynthetic processGO:0046390870.013
negative regulation of phosphate metabolic processGO:0045936800.013
response to woundingGO:00096112540.013
organophosphate catabolic processGO:00464341480.013
regulation of synaptic transmissionGO:00508041410.013
negative regulation of transportGO:00510511360.013
regulation of cyclic nucleotide biosynthetic processGO:0030802450.013
behaviorGO:00076102050.013
positive regulation of phosphate metabolic processGO:00459372620.013
cellular protein complex assemblyGO:0043623440.013
negative regulation of protein metabolic processGO:00512481140.013
positive regulation of catalytic activityGO:00430851840.013
response to growth factorGO:00708481890.013
purine nucleotide catabolic processGO:00061951360.013
regulation of transferase activityGO:00513381230.012
head developmentGO:00603222470.012
regulation of developmental growthGO:0048638450.012
positive regulation of rna biosynthetic processGO:19026801970.012
regulation of multicellular organismal developmentGO:20000263760.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
cardiac muscle contractionGO:0060048270.012
peptide hormone secretionGO:0030072840.012
embryonic skeletal system morphogenesisGO:004870430.012
regulation of cellular amino acid metabolic processGO:000652120.012
purine nucleoside metabolic processGO:00422781690.012
biological adhesionGO:00226101100.012
positive regulation of multicellular organismal processGO:00512403870.012
protein autophosphorylationGO:0046777660.012
protein localization to membraneGO:0072657360.012
Human
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
regulation of neurotransmitter levelsGO:0001505420.012
microtubule organizing center organizationGO:003102310.012
cell type specific apoptotic processGO:00972851340.012
cellular amine metabolic processGO:0044106380.012
neuromuscular synaptic transmissionGO:000727420.012
cellular nitrogen compound catabolic processGO:00442701630.012
nucleotide catabolic processGO:00091661390.012
positive regulation of developmental processGO:00510942830.012
ribonucleoside metabolic processGO:00091191740.012
heart developmentGO:0007507720.012
single organism membrane organizationGO:0044802740.012
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.012
bmp signaling pathwayGO:003050940.012
response to lipopolysaccharideGO:00324961910.012
dephosphorylationGO:0016311980.012
signal releaseGO:00230611450.012
neurotransmitter transportGO:0006836420.012
multicellular organismal signalingGO:0035637440.012
negative regulation of homeostatic processGO:0032845470.012
oxidation reduction processGO:00551143040.012
response to zinc ionGO:0010043390.012
positive regulation of serotonin secretionGO:001406410.011
glucose homeostasisGO:0042593750.011
negative regulation of transcription dna templatedGO:00458921160.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of notch signaling pathwayGO:000859330.011
mesoderm formationGO:000170710.011
regulation of neuron projection developmentGO:00109751610.011
response to oxidative stressGO:00069791860.011
positive regulation of nucleotide metabolic processGO:0045981910.011
response to external biotic stimulusGO:00432072210.011
nucleoside metabolic processGO:00091161790.011
rna localizationGO:000640340.011
rho protein signal transductionGO:0007266110.011
regulation of intracellular signal transductionGO:19025312180.011
intracellular protein transportGO:0006886790.011
Human
regulation of cell projection organizationGO:00313441750.011
hormone secretionGO:00468791150.011
ribonucleoside catabolic processGO:00424541260.011
amide transportGO:00428861050.011
alpha amino acid metabolic processGO:1901605710.011
single organism behaviorGO:00447081300.011
sex differentiationGO:00075481130.011
cellular response to cytokine stimulusGO:00713451270.011
regulation of sequestering of calcium ionGO:0051282260.011
adult locomotory behaviorGO:000834440.011
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.011
organic hydroxy compound metabolic processGO:19016151150.011
endomembrane system organizationGO:0010256480.011
peptide secretionGO:0002790860.011
insulin secretionGO:0030073690.011
lipid storageGO:001991510.011
regenerationGO:00310991630.011
negative regulation of programmed cell deathGO:00430691830.011
regulation of ion homeostasisGO:2000021630.011
rna biosynthetic processGO:00327743800.010
cellular response to carbohydrate stimulusGO:0071322720.010
receptor localization to synapseGO:009712020.010
fatty acid metabolic processGO:0006631990.010
organic acid biosynthetic processGO:0016053830.010
potassium ion transportGO:0006813970.010
locomotory exploration behaviorGO:003564110.010
vasculogenesisGO:000157030.010
mesodermal cell differentiationGO:004833310.010
development of primary sexual characteristicsGO:00451371070.010
synaptic vesicle primingGO:001608240.010
positive regulation of programmed cell deathGO:00430681570.010
carbohydrate homeostasisGO:0033500750.010
negative regulation of rna metabolic processGO:00512531230.010
regulation of heart contractionGO:0008016480.010
regulation of neuron differentiationGO:00456642080.010
carbohydrate derivative catabolic processGO:19011361470.010
circadian behaviorGO:0048512240.010
regulation of protein transportGO:0051223680.010
circadian regulation of gene expressionGO:003292230.010
muscle contractionGO:0006936880.010
carboxylic acid biosynthetic processGO:0046394830.010
protein targetingGO:0006605610.010
Human
response to electrical stimulusGO:0051602560.010
dna metabolic processGO:0006259960.010
cellular lipid metabolic processGO:00442552080.010
defense response to gram negative bacteriumGO:005082930.010
regulation of protein kinase activityGO:00458591050.010
regulation of nervous system developmentGO:00519602640.010
regulation of protein localizationGO:0032880810.010
epithelial cell differentiationGO:0030855710.010
male gamete generationGO:0048232990.010
cellular macromolecule localizationGO:00707271220.010
Human
regulation of cellular amine metabolic processGO:003323880.010

Chm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
Human
nervous system diseaseDOID:86300.023
Human
cardiovascular system diseaseDOID:128700.013
central nervous system diseaseDOID:33100.013
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.012
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012
inherited metabolic disorderDOID:65500.011