Rattus norvegicus

7 known processes

Thop1

thimet oligopeptidase 1

(Aliases: EP24.15,MGC93105)

Thop1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna metabolic processGO:00160704060.331
positive regulation of nucleobase containing compound metabolic processGO:00459353190.294
nucleic acid templated transcriptionGO:00976593790.235
aromatic compound catabolic processGO:00194391680.232
organophosphate catabolic processGO:00464341480.217
heterocycle catabolic processGO:00467001670.200
transcription dna templatedGO:00063513770.196
regulation of rna biosynthetic processGO:20011413810.196
protein localizationGO:00081041910.187
macromolecule localizationGO:00330362520.182
regulation of transcription from rna polymerase ii promoterGO:00063572340.181
rna biosynthetic processGO:00327743800.169
positive regulation of nitrogen compound metabolic processGO:00511733340.168
purine nucleotide catabolic processGO:00061951360.164
positive regulation of transcription dna templatedGO:00458931970.143
nucleotide metabolic processGO:00091172790.129
carbohydrate derivative metabolic processGO:19011353460.129
cell cell signalingGO:00072673350.117
positive regulation of macromolecule biosynthetic processGO:00105572470.108
organic substance catabolic processGO:19015753160.103
reproductive system developmentGO:00614581280.103
response to extracellular stimulusGO:00099913800.103
regulation of apoptotic processGO:00429813350.102
reproductive processGO:00224143720.096
positive regulation of gene expressionGO:00106282440.093
nucleobase containing small molecule metabolic processGO:00550863160.092
regulation of nucleic acid templated transcriptionGO:19035063800.091
cellular catabolic processGO:00442482950.090
nucleoside phosphate metabolic processGO:00067532830.088
nucleoside metabolic processGO:00091161790.086
nucleotide catabolic processGO:00091661390.085
transcription from rna polymerase ii promoterGO:00063662520.085
developmental process involved in reproductionGO:00030061590.083
protein complex biogenesisGO:00702712630.081
response to nutrientGO:00075842480.081
positive regulation of biosynthetic processGO:00098913190.081
regulation of rna metabolic processGO:00512523910.079
ribonucleotide metabolic processGO:00092592310.079
response to peptide hormoneGO:00434342780.077
gonad developmentGO:00084061040.074
anatomical structure morphogenesisGO:00096532980.074
regulation of cell proliferationGO:00421273590.072
reproductive structure developmentGO:00486081280.072
regulation of protein metabolic processGO:00512462890.071
synaptic transmissionGO:00072682350.070
organophosphate metabolic processGO:00196373700.070
cellular protein localizationGO:00346131220.069
vesicle mediated transportGO:00161921810.068
reproductionGO:00000032450.067
regulation of transcription dna templatedGO:00063553740.067
regulation of phosphorus metabolic processGO:00511743490.066
catabolic processGO:00090563510.065
positive regulation of rna biosynthetic processGO:19026801970.064
purine containing compound metabolic processGO:00725212530.063
positive regulation of cellular biosynthetic processGO:00313282950.063
multi organism reproductive processGO:00447032620.062
establishment of protein localizationGO:00451841410.057
regulation of phosphorylationGO:00423252480.056
protein complex subunit organizationGO:00718223020.056
positive regulation of phosphate metabolic processGO:00459372620.056
brain developmentGO:00074202470.056
single organism reproductive processGO:00447022970.056
protein targetingGO:0006605610.055
nucleobase containing compound catabolic processGO:00346551520.054
macromolecular complex assemblyGO:00650032730.054
positive regulation of developmental processGO:00510942830.054
negative regulation of gene expressionGO:00106291990.054
programmed cell deathGO:00125013920.054
cellular macromolecule localizationGO:00707271220.053
single organism cellular localizationGO:19025801020.052
head developmentGO:00603222470.051
regulation of cellular localizationGO:00603412630.051
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.051
purine ribonucleoside metabolic processGO:00461281680.051
purine nucleoside catabolic processGO:00061521240.050
multicellular organismal reproductive processGO:00486092330.050
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.049
multicellular organism reproductionGO:00325042330.049
response to nutrient levelsGO:00316673700.049
central nervous system developmentGO:00074173110.048
cellular amine metabolic processGO:0044106380.047
carbon catabolite activation of transcriptionGO:004599110.047
oxoacid metabolic processGO:00434362900.046
organic cyclic compound catabolic processGO:19013611750.046
purine containing compound catabolic processGO:00725231380.046
immune system processGO:00023762040.046
protein complex assemblyGO:00064612630.045
positive regulation of rna metabolic processGO:00512542030.045
carbohydrate derivative catabolic processGO:19011361470.045
rhythmic processGO:00485111560.044
positive regulation of nucleic acid templated transcriptionGO:19035081970.044
action potentialGO:0001508540.043
carboxylic acid metabolic processGO:00197522890.043
macromolecular complex subunit organizationGO:00439333390.043
dna metabolic processGO:0006259960.042
negative regulation of nucleobase containing compound metabolic processGO:00459341530.041
intracellular transportGO:00469071850.041
cellular nitrogen compound catabolic processGO:00442701630.041
regulation of programmed cell deathGO:00430673410.041
nitrogen compound transportGO:00717052290.041
ribose phosphate metabolic processGO:00196932350.040
chromosome segregationGO:000705920.039
neurological system processGO:00508772190.039
positive regulation of molecular functionGO:00440932300.039
positive regulation of phosphorus metabolic processGO:00105622620.039
organonitrogen compound catabolic processGO:19015651790.039
nucleoside phosphate catabolic processGO:19012921400.038
purine nucleoside metabolic processGO:00422781690.038
glycosyl compound catabolic processGO:19016581260.038
single organism biosynthetic processGO:00447113420.038
purine nucleoside triphosphate catabolic processGO:00091461220.038
anion transportGO:00068201780.038
negative regulation of metabolic processGO:00098923310.037
regulation of synaptic growth at neuromuscular junctionGO:000858210.037
nuclear transportGO:0051169490.037
negative regulation of response to stimulusGO:00485851550.037
cellular component biogenesisGO:00440853680.037
ribonucleoside catabolic processGO:00424541260.037
cellular component assemblyGO:00226073600.037
amine metabolic processGO:0009308380.036
negative regulation of cellular metabolic processGO:00313242810.036
organic acid metabolic processGO:00060822920.036
response to peptideGO:19016522920.036
purine ribonucleotide metabolic processGO:00091502270.035
purine nucleoside triphosphate metabolic processGO:00091441410.035
positive regulation of neurogenesisGO:00507691650.035
positive regulation of multicellular organismal processGO:00512403870.035
regulation of protein modification processGO:00313991940.034
negative regulation of cell communicationGO:00106481580.034
regulation of cell differentiationGO:00455953200.034
purine nucleotide metabolic processGO:00061632290.034
negative regulation of rna metabolic processGO:00512531230.034
regulation of neurogenesisGO:00507672470.033
growthGO:00400071650.033
negative regulation of macromolecule metabolic processGO:00106052600.033
regulation of multicellular organismal developmentGO:20000263760.033
positive regulation of nucleotide metabolic processGO:0045981910.033
regulation of membrane potentialGO:00423911100.033
purine ribonucleoside catabolic processGO:00461301240.033
regulation of molecular functionGO:00650093980.032
regulation of cellular protein metabolic processGO:00322682670.032
positive regulation of cell deathGO:00109421840.032
gliogenesisGO:0042063930.032
protein oligomerizationGO:00512591910.031
positive regulation of nervous system developmentGO:00519621780.031
regulation of phosphate metabolic processGO:00192203490.031
cation transportGO:00068123820.031
negative regulation of signalingGO:00230571570.031
cardiovascular system developmentGO:00723581340.031
gtp catabolic processGO:0006184710.031
ribonucleoside triphosphate metabolic processGO:00091991410.031
response to glucoseGO:00097491360.030
purine ribonucleoside triphosphate catabolic processGO:00092071220.030
positive regulation of cell proliferationGO:00082842490.030
positive regulation of transcription factor import into nucleusGO:004299340.030
locomotionGO:00400112370.030
protein transportGO:00150311320.029
gland developmentGO:00487321550.029
multicellular organismal signalingGO:0035637440.028
positive regulation of phosphorylationGO:00423271770.028
single organism nuclear importGO:1902593350.028
protein homooligomerizationGO:0051260910.027
nucleoside monophosphate metabolic processGO:0009123930.027
apoptotic processGO:00069153810.027
chemical homeostasisGO:00488782920.027
cellular amino acid metabolic processGO:00065201070.027
cellular response to peptide hormone stimulusGO:00713751200.027
cellular response to oxygen containing compoundGO:19017013860.027
cellular response to growth factor stimulusGO:00713631620.027
negative regulation of biosynthetic processGO:00098901680.027
transmission of nerve impulseGO:0019226420.026
positive regulation of catalytic activityGO:00430851840.026
organelle organizationGO:00069962660.026
regulation of catabolic processGO:00098941130.026
positive regulation of purine nucleotide metabolic processGO:1900544910.026
tissue developmentGO:00098882520.026
secretionGO:00469033070.025
gtp metabolic processGO:0046039720.025
ribonucleoside triphosphate catabolic processGO:00092031220.025
negative regulation of cell deathGO:00605482290.025
neuronal action potentialGO:0019228350.025
cellular response to endogenous stimulusGO:00714953770.024
nucleoside triphosphate catabolic processGO:00091431230.024
single organism catabolic processGO:00447122830.024
sex differentiationGO:00075481130.024
response to heatGO:0009408600.024
protein localization to organelleGO:0033365570.024
nucleoside catabolic processGO:00091641260.024
positive regulation of cellular amine metabolic processGO:003324030.024
regenerationGO:00310991630.024
meiotic cell cycle processGO:190304630.024
positive regulation of protein metabolic processGO:00512471780.024
ribonucleoside metabolic processGO:00091191740.023
ion transmembrane transportGO:00342203650.023
cellular response to hormone stimulusGO:00328702470.023
cellular response to nitrogen compoundGO:19016992100.023
development of primary sexual characteristicsGO:00451371070.023
negative regulation of macromolecule biosynthetic processGO:00105581480.023
axon ensheathmentGO:0008366400.023
cellular response to organonitrogen compoundGO:00714171970.023
homeostatic processGO:00425923310.023
regulation of purine nucleotide metabolic processGO:19005421150.023
negative regulation of signal transductionGO:0009968830.023
cellular response to stressGO:00335542690.023
positive regulation of cellular component organizationGO:00511302000.022
regulation of catalytic activityGO:00507903040.022
response to inorganic substanceGO:00100353770.022
neuron developmentGO:00486662860.022
cell cycle processGO:0022402570.022
cell growthGO:00160491040.022
negative regulation of cellular response to insulin stimulusGO:1900077110.022
protein phosphorylationGO:00064683450.022
organophosphate biosynthetic processGO:00904071430.022
protein localization to nucleusGO:0034504390.022
response to mineralocorticoidGO:0051385490.022
double strand break repairGO:000630210.022
response to corticosteroidGO:00319602350.022
regulation of cellular amine metabolic processGO:003323880.022
regulation of ion transportGO:00432692450.022
regulation of cell cycleGO:0051726730.021
eye morphogenesisGO:004859240.021
regulation of secretion by cellGO:19035302080.021
response to hypoxiaGO:00016662310.021
negative regulation of molecular functionGO:00440921330.021
nucleoside triphosphate metabolic processGO:00091411440.021
regulation of system processGO:00440572080.021
purine ribonucleoside triphosphate metabolic processGO:00092051400.021
ribonucleotide catabolic processGO:00092611360.021
negative regulation of nitrogen compound metabolic processGO:00511721610.021
female pregnancyGO:00075651220.020
response to growth factorGO:00708481890.020
negative regulation of apoptotic processGO:00430661810.020
purine ribonucleotide catabolic processGO:00091541360.020
negative regulation of transcription dna templatedGO:00458921160.020
ncrna processingGO:003447030.020
organonitrogen compound biosynthetic processGO:19015661670.020
response to decreased oxygen levelsGO:00362932370.020
carboxylic acid transportGO:00469421150.020
neuron differentiationGO:00301823680.020
single organism intracellular transportGO:19025821660.020
regulation of intracellular transportGO:0032386650.019
glial cell differentiationGO:0010001650.019
regulation of cellular ketone metabolic processGO:0010565270.019
proteolysisGO:00065081750.019
positive regulation of cellular catabolic processGO:0031331710.019
regulation of nucleotide catabolic processGO:0030811650.019
cell projection organizationGO:00300303020.019
response to oxygen levelsGO:00704822650.019
protein import into nucleusGO:0006606350.019
female gonad developmentGO:0008585530.019
positive regulation of cell differentiationGO:00455972170.019
ensheathment of neuronsGO:0007272400.018
defense responseGO:00069521940.018
sexual reproductionGO:00199531480.018
cell cycleGO:00070491010.018
response to hexoseGO:00097461440.018
negative regulation of rna biosynthetic processGO:19026791180.018
behaviorGO:00076102050.018
cellular component movementGO:00069282480.018
regulation of dna metabolic processGO:0051052600.018
gamete generationGO:00072761240.018
positive regulation of signal transductionGO:00099671750.018
regulation of cellular catabolic processGO:00313291010.018
regulation of nervous system developmentGO:00519602640.018
agingGO:00075682410.018
regulation of cellular amino acid metabolic processGO:000652120.018
cellular response to peptideGO:19016531330.018
positive regulation of protein modification processGO:00314011420.018
positive regulation of signalingGO:00230562700.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
response to carbohydrateGO:00097431830.017
regulation of cellular component organizationGO:00511283680.017
transmembrane transportGO:00550854120.017
response to radiationGO:00093141370.017
response to glucocorticoidGO:00513842230.017
positive regulation of cell developmentGO:00107201760.017
cell activationGO:0001775970.017
coenzyme metabolic processGO:0006732860.017
divalent metal ion transportGO:00708381320.017
regulation of neuron deathGO:19012141150.016
developmental growthGO:00485891000.016
regulation of nucleoside metabolic processGO:0009118660.016
necroptotic processGO:007026620.016
carbohydrate metabolic processGO:00059751300.016
secretion by cellGO:00329402480.016
motor neuron axon guidanceGO:000804510.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of nucleotide metabolic processGO:00061401170.016
nucleocytoplasmic transportGO:0006913480.016
protein modification by small protein conjugation or removalGO:0070647350.016
eye developmentGO:0001654500.016
response to estrogenGO:00436272320.016
positive regulation of protein phosphorylationGO:00019341350.016
negative regulation of programmed cell deathGO:00430691830.015
negative regulation of cell cycle phase transitionGO:190198840.015
guanosine containing compound metabolic processGO:1901068740.015
heart developmentGO:0007507720.015
signal transduction by phosphorylationGO:00230141440.015
peptidyl amino acid modificationGO:00181931260.015
heart morphogenesisGO:000300730.015
regulation of protein phosphorylationGO:00019321830.015
spindle organizationGO:000705120.015
cellular response to organic cyclic compoundGO:00714072020.015
adult locomotory behaviorGO:000834440.015
protein heterooligomerizationGO:0051291890.015
regulation of hydrolase activityGO:00513361430.015
negative regulation of protein metabolic processGO:00512481140.015
dendrite developmentGO:0016358720.014
regulation of neuron differentiationGO:00456642080.014
embryo developmentGO:0009790490.014
establishment of protein localization to organelleGO:0072594440.014
lipid biosynthetic processGO:00086101280.014
small molecule biosynthetic processGO:00442831240.014
neuron projection developmentGO:00311752730.014
purine nucleoside monophosphate metabolic processGO:0009126840.014
positive regulation of catabolic processGO:0009896780.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
g protein coupled receptor signaling pathwayGO:00071862420.014
negative regulation of rna splicingGO:003311930.014
ribonucleoside monophosphate metabolic processGO:0009161880.014
cytoplasmic transportGO:00164821150.014
positive regulation of neuron differentiationGO:00456661260.014
lipid storageGO:001991510.014
glycosyl compound metabolic processGO:19016571820.014
amino acid transportGO:0006865700.014
regulation of signal transductionGO:00099663180.013
gastrulationGO:000736920.013
regulation of gtpase activityGO:0043087570.013
protein targeting to nucleusGO:0044744350.013
positive regulation of cell communicationGO:00106472710.013
dna modificationGO:0006304120.013
negative regulation of neuron deathGO:1901215690.013
mrna metabolic processGO:0016071200.013
detection of visible lightGO:000958430.013
development of primary female sexual characteristicsGO:0046545560.013
protein importGO:0017038370.013
protein localization to membraneGO:0072657360.013
viral transcriptionGO:001908320.013
cell projection morphogenesisGO:00488581230.013
cardiac chamber developmentGO:000320510.013
localization of cellGO:00516742020.013
calcium ion homeostasisGO:00550741620.013
negative regulation of cell proliferationGO:00082851190.013
purine ribonucleoside monophosphate metabolic processGO:0009167840.013
neuromuscular synaptic transmissionGO:000727420.013
cellular chemical homeostasisGO:00550822470.013
circulatory system developmentGO:00723591340.013
cell type specific apoptotic processGO:00972851340.013
single organism membrane organizationGO:0044802740.013
regulation of protein localizationGO:0032880810.013
response to purine containing compoundGO:00140741260.012
regulation of protein import into nucleusGO:0042306240.012
nucleoside phosphate biosynthetic processGO:19012931020.012
cellular ketone metabolic processGO:0042180510.012
positive regulation of gtpase activityGO:0043547470.012
neuron deathGO:00709971270.012
regulation of cell projection organizationGO:00313441750.012
sensory organ developmentGO:0007423740.012
regulation of secretionGO:00510462240.012
monosaccharide metabolic processGO:0005996610.012
response to temperature stimulusGO:0009266940.012
negative regulation of developmental processGO:00510931250.012
organelle fissionGO:0048285250.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
response to vitaminGO:00332731310.012
histone h3 acetylationGO:004396620.012
positive regulation of cellular protein metabolic processGO:00322701670.012
organic acid transportGO:00158491160.012
male gamete generationGO:0048232990.012
serine family amino acid metabolic processGO:0009069120.012
ovulation cycleGO:0042698670.012
membrane organizationGO:0061024940.012
negative regulation of insulin receptor signaling pathwayGO:0046627100.012
metal ion homeostasisGO:00550651860.012
carbohydrate derivative biosynthetic processGO:19011371240.012
cell migrationGO:00164771970.012
hexose metabolic processGO:0019318580.011
negative regulation of cellular component organizationGO:0051129830.011
hormone transportGO:00099141210.011
dendrite morphogenesisGO:0048813430.011
regulation of intracellular signal transductionGO:19025312180.011
organic anion transportGO:00157111320.011
metal ion transportGO:00300012890.011
regulation of neuron projection developmentGO:00109751610.011
female sex differentiationGO:0046660590.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
negative regulation of cellular biosynthetic processGO:00313271610.011
organic acid biosynthetic processGO:0016053830.011
axis specificationGO:000979840.011
response to estradiolGO:00323551640.011
insulin receptor signaling pathwayGO:0008286240.011
positive regulation of nucleoside metabolic processGO:0045979550.011
cell morphogenesis involved in differentiationGO:00009041190.011
synaptic growth at neuromuscular junctionGO:005112410.011
single organism carbohydrate metabolic processGO:00447231180.011
cellular homeostasisGO:00197252520.011
circulatory system processGO:00030131830.011
central nervous system neuron axonogenesisGO:002195510.011
cation homeostasisGO:00550801950.011
positive regulation of response to stimulusGO:00485842850.011
nucleoside monophosphate catabolic processGO:0009125560.011
cellular protein complex assemblyGO:0043623440.011
response to cytokineGO:00340972150.011
response to biotic stimulusGO:00096072260.011
regulation of growthGO:00400081050.011
cellular response to cytokine stimulusGO:00713451270.011
positive regulation of nucleotide catabolic processGO:0030813530.011
positive regulation of apoptotic processGO:00430651540.011
regulation of nucleocytoplasmic transportGO:0046822280.011
cellular amino acid biosynthetic processGO:0008652320.010
cell motilityGO:00488702020.010
regulation of cell growthGO:0001558850.010
myelinationGO:0042552390.010
nucleotide biosynthetic processGO:0009165980.010
leukocyte activationGO:0045321760.010
negative regulation of transportGO:00510511360.010
positive regulation of transportGO:00510502450.010
receptor mediated endocytosisGO:0006898420.010
positive regulation of cell projection organizationGO:00313461110.010
regulation of proteasomal protein catabolic processGO:006113640.010
regulation of canonical wnt signaling pathwayGO:006082840.010
multicellular organism growthGO:003526410.010
leukocyte differentiationGO:0002521300.010
cytosolic calcium ion homeostasisGO:00514801400.010
response to activityGO:0014823730.010
positive regulation of gtp catabolic processGO:0033126480.010
response to light stimulusGO:0009416520.010
response to corticosteroneGO:0051412400.010
multi multicellular organism processGO:00447061380.010
negative regulation of cellular protein metabolic processGO:00322691060.010
cellular cation homeostasisGO:00300031800.010
cellular response to nutrientGO:0031670300.010
camera type eye morphogenesisGO:004859320.010

Thop1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015
cardiovascular system diseaseDOID:128700.015
disease of anatomical entityDOID:700.015
nervous system diseaseDOID:86300.013
organ system cancerDOID:005068600.012