IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Igfbpl1

insulin-like growth factor binding protein-like 1

RGD: 1305656
Ensembl: ENSRNOG00000011320
Entrez: 366366
UniProtKB: B0BN16

Process Predictions
Disease Predictions

Igfbpl1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transport	GO:0006812	382	0.052
regulation of cell development	GO:0060284	263	0.052
cellular amino acid metabolic process	GO:0006520	107	0.050
neuron projection development	GO:0031175	273	0.049
oligopeptide transport	GO:0006857	4	0.044
choline transport	GO:0015871	4	0.042
macromolecular complex assembly	GO:0065003	273	0.037
cell morphogenesis	GO:0000902	142	0.037
regulation of phosphorus metabolic process	GO:0051174	349	0.036
cellular component morphogenesis	GO:0032989	155	0.036
action potential	GO:0001508	54	0.035
cellular response to oxygen containing compound	GO:1901701	386	0.034
transmembrane transport	GO:0055085	412	0.034
homeostatic process	GO:0042592	331	0.034
protein complex assembly	GO:0006461	263	0.034
response to decreased oxygen levels	GO:0036293	237	0.034
regulation of transcription dna templated	GO:0006355	374	0.033
organic acid metabolic process	GO:0006082	292	0.033
response to oxygen levels	GO:0070482	265	0.032
vascular process in circulatory system	GO:0003018	96	0.031
establishment of tissue polarity	GO:0007164	2	0.030
single organism reproductive process	GO:0044702	297	0.030	Rat
programmed cell death	GO:0012501	392	0.030
regulation of cell proliferation	GO:0042127	359	0.030
cellular component movement	GO:0006928	248	0.029
nucleobase containing small molecule metabolic process	GO:0055086	316	0.029
cellular response to stress	GO:0033554	269	0.029
regulation of cellular amino acid metabolic process	GO:0006521	2	0.029
regulation of cellular amine metabolic process	GO:0033238	8	0.029
cellular response to endogenous stimulus	GO:0071495	377	0.028	Rat
neuron development	GO:0048666	286	0.027
regulation of rna biosynthetic process	GO:2001141	381	0.027
modified amino acid transport	GO:0072337	12	0.026
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.025
regulation of molecular function	GO:0065009	398	0.025
cell part morphogenesis	GO:0032990	123	0.025
cellular component biogenesis	GO:0044085	368	0.025
neuron differentiation	GO:0030182	368	0.025
peptidyl tyrosine phosphorylation	GO:0018108	72	0.024
oxoacid metabolic process	GO:0043436	290	0.024
cellular ketone metabolic process	GO:0042180	51	0.024
regulation of protein modification process	GO:0031399	194	0.024
positive regulation of cell differentiation	GO:0045597	217	0.023
anatomical structure morphogenesis	GO:0009653	298	0.023
response to other organism	GO:0051707	220	0.023
carboxylic acid metabolic process	GO:0019752	289	0.023
amine metabolic process	GO:0009308	38	0.022
response to nutrient	GO:0007584	248	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.022
positive regulation of catalytic activity	GO:0043085	184	0.022
cellular amine metabolic process	GO:0044106	38	0.022
cell projection organization	GO:0030030	302	0.021
regulation of catalytic activity	GO:0050790	304	0.021
positive regulation of protein phosphorylation	GO:0001934	135	0.021
positive regulation of phosphate metabolic process	GO:0045937	262	0.021
positive regulation of defense response	GO:0031349	37	0.021
positive regulation of cellular protein metabolic process	GO:0032270	167	0.021
gland development	GO:0048732	155	0.021
regulation of cellular protein metabolic process	GO:0032268	267	0.021
regulation of multicellular organismal development	GO:2000026	376	0.020
macromolecular complex subunit organization	GO:0043933	339	0.020
antibiotic transport	GO:0042891	2	0.020
reproductive process	GO:0022414	372	0.020	Rat
gliogenesis	GO:0042063	93	0.020
response to hypoxia	GO:0001666	231	0.020
regulation of cellular ketone metabolic process	GO:0010565	27	0.020
positive regulation of cell proliferation	GO:0008284	249	0.020
peptidyl amino acid modification	GO:0018193	126	0.020
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.020
protein phosphorylation	GO:0006468	345	0.020
neuron projection morphogenesis	GO:0048812	122	0.019
carbohydrate derivative metabolic process	GO:1901135	346	0.019
rna biosynthetic process	GO:0032774	380	0.019
positive regulation of cell projection organization	GO:0031346	111	0.019
response to wounding	GO:0009611	254	0.019
protein complex biogenesis	GO:0070271	263	0.019
wnt signaling pathway planar cell polarity pathway	GO:0060071	2	0.019
intracellular signal transduction	GO:0035556	314	0.019
positive regulation of kinase activity	GO:0033674	77	0.019
response to extracellular stimulus	GO:0009991	380	0.019
response to ketone	GO:1901654	182	0.018	Rat
regulation of hormone levels	GO:0010817	187	0.018
cellular homeostasis	GO:0019725	252	0.018
regulation of signal transduction	GO:0009966	318	0.018
cellular response to organonitrogen compound	GO:0071417	197	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
regulation of cell projection size	GO:0032536	1	0.018
negative regulation of developmental process	GO:0051093	125	0.018
blood circulation	GO:0008015	183	0.018
negative regulation of nervous system development	GO:0051961	79	0.017
positive regulation of neuron projection development	GO:0010976	99	0.017
regulation of cell differentiation	GO:0045595	320	0.017
response to hexose	GO:0009746	144	0.016
positive regulation of biosynthetic process	GO:0009891	319	0.016
single organism intracellular transport	GO:1902582	166	0.016
organophosphate metabolic process	GO:0019637	370	0.016
positive regulation of phosphorylation	GO:0042327	177	0.016
metestrus	GO:0060210	1	0.016
regulation of establishment of planar polarity	GO:0090175	2	0.016
peptidyl tyrosine modification	GO:0018212	72	0.016
cellular response to growth factor stimulus	GO:0071363	162	0.016
response to nutrient levels	GO:0031667	370	0.016
cell type specific apoptotic process	GO:0097285	134	0.016
positive regulation of developmental process	GO:0051094	283	0.016
cellular component assembly	GO:0022607	360	0.016
transmission of nerve impulse	GO:0019226	42	0.016
regulation of cellular component organization	GO:0051128	368	0.016
heterocycle catabolic process	GO:0046700	167	0.016
regulation of neurogenesis	GO:0050767	247	0.016
regulation of phosphate metabolic process	GO:0019220	349	0.016
nucleotide metabolic process	GO:0009117	279	0.016
drug transmembrane transport	GO:0006855	13	0.016
response to oxidative stress	GO:0006979	186	0.016
activation of protein kinase activity	GO:0032147	47	0.015
regulation of anatomical structure size	GO:0090066	135	0.015
cation transmembrane transport	GO:0098655	263	0.015
axon development	GO:0061564	96	0.015
cellular response to external stimulus	GO:0071496	118	0.015
gastrulation	GO:0007369	2	0.015
rna metabolic process	GO:0016070	406	0.015
regulation of muscle system process	GO:0090257	79	0.015
regulation of mesenchymal cell proliferation	GO:0010464	4	0.015
regulation of intracellular signal transduction	GO:1902531	218	0.015
positive regulation of phosphorus metabolic process	GO:0010562	262	0.015
amino acid transport	GO:0006865	70	0.015
positive regulation of multicellular organismal process	GO:0051240	387	0.015
regulation of rna metabolic process	GO:0051252	391	0.015
intestinal absorption	GO:0050892	3	0.015
multicellular organismal signaling	GO:0035637	44	0.015
cell morphogenesis involved in differentiation	GO:0000904	119	0.015
neuronal action potential	GO:0019228	35	0.015
salivary gland development	GO:0007431	3	0.015
positive regulation of cell migration	GO:0030335	96	0.014
purine ribonucleotide metabolic process	GO:0009150	227	0.014
protein homooligomerization	GO:0051260	91	0.014
tripeptide transport	GO:0042939	2	0.014
liver development	GO:0001889	90	0.014
transcription dna templated	GO:0006351	377	0.014
appendage morphogenesis	GO:0035107	4	0.014
response to glucose	GO:0009749	136	0.014
positive regulation of protein kinase activity	GO:0045860	73	0.014
locomotion	GO:0040011	237	0.014
formation of primary germ layer	GO:0001704	1	0.014
cellular response to lipid	GO:0071396	201	0.014
cellular response to nitrogen compound	GO:1901699	210	0.014
cellular chemical homeostasis	GO:0055082	247	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.014
response to inorganic substance	GO:0010035	377	0.014
brain development	GO:0007420	247	0.014
ribonucleoside metabolic process	GO:0009119	174	0.014
regulation of nervous system development	GO:0051960	264	0.014
positive regulation of transferase activity	GO:0051347	81	0.013
limb morphogenesis	GO:0035108	4	0.013
regulation of protein metabolic process	GO:0051246	289	0.013
cell cycle	GO:0007049	101	0.013
purine containing compound catabolic process	GO:0072523	138	0.013
b cell differentiation	GO:0030183	2	0.013
metanephric comma shaped body morphogenesis	GO:0072278	2	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.013
cellular response to abiotic stimulus	GO:0071214	85	0.013
vasoconstriction	GO:0042310	54	0.013
cell projection morphogenesis	GO:0048858	123	0.013
glycosyl compound metabolic process	GO:1901657	182	0.013
purine containing compound metabolic process	GO:0072521	253	0.013
response to peptide	GO:1901652	292	0.013
negative regulation of cell proliferation	GO:0008285	119	0.013
cellular response to hormone stimulus	GO:0032870	247	0.013	Rat
organic hydroxy compound transport	GO:0015850	77	0.013
positive regulation of molecular function	GO:0044093	230	0.013
cell growth	GO:0016049	104	0.013
response to reactive oxygen species	GO:0000302	120	0.012
response to cytokine	GO:0034097	215	0.012
response to vitamin	GO:0033273	131	0.012
positive regulation of cell death	GO:0010942	184	0.012
negative regulation of metabolic process	GO:0009892	331	0.012
organic cyclic compound catabolic process	GO:1901361	175	0.012
regeneration	GO:0031099	163	0.012
negative regulation of cell communication	GO:0010648	158	0.012
carboxylic acid transport	GO:0046942	115	0.012
cellular response to alcohol	GO:0097306	87	0.012
regulation of phosphorylation	GO:0042325	248	0.012
divalent inorganic cation transport	GO:0072511	134	0.012
axis specification	GO:0009798	4	0.012
neurotransmitter uptake	GO:0001504	3	0.012
negative regulation of cell development	GO:0010721	82	0.012
nucleoside phosphate metabolic process	GO:0006753	283	0.012
defense response	GO:0006952	194	0.012
positive regulation of cellular biosynthetic process	GO:0031328	295	0.012
jnk cascade	GO:0007254	28	0.012
positive regulation of mapk cascade	GO:0043410	92	0.012
mapk cascade	GO:0000165	140	0.012
glial cell differentiation	GO:0010001	65	0.012
regulation of membrane potential	GO:0042391	110	0.012
reproduction	GO:0000003	245	0.012
heart morphogenesis	GO:0003007	3	0.012
regulation of cell projection organization	GO:0031344	175	0.012
intracellular transport	GO:0046907	185	0.012
inorganic cation transmembrane transport	GO:0098662	202	0.012
ribose phosphate metabolic process	GO:0019693	235	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
protein complex subunit organization	GO:0071822	302	0.011
response to monosaccharide	GO:0034284	159	0.011
response to axon injury	GO:0048678	59	0.011
myelination	GO:0042552	39	0.011
hormone transport	GO:0009914	121	0.011
lipid metabolic process	GO:0006629	283	0.011	Rat
cell cell signaling	GO:0007267	335	0.011
signal release	GO:0023061	145	0.011
positive regulation of transcription dna templated	GO:0045893	197	0.011
non canonical wnt signaling pathway	GO:0035567	3	0.011
positive regulation of cell adhesion	GO:0045785	30	0.011
drug transport	GO:0015893	18	0.011
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.011
protein oligomerization	GO:0051259	191	0.011
positive regulation of signaling	GO:0023056	270	0.011
lens fiber cell differentiation	GO:0070306	3	0.011
epithelial cell differentiation	GO:0030855	71	0.011
ion transmembrane transport	GO:0034220	365	0.011
regulation of canonical wnt signaling pathway	GO:0060828	4	0.011
single organism biosynthetic process	GO:0044711	342	0.011	Rat
negative regulation of canonical wnt signaling pathway	GO:0090090	4	0.011
response to ethanol	GO:0045471	162	0.011
immune system process	GO:0002376	204	0.011
negative regulation of cell differentiation	GO:0045596	99	0.011
regulation of tube size	GO:0035150	89	0.011
regulation of mapk cascade	GO:0043408	116	0.011
regulation of cell growth	GO:0001558	85	0.011
cellular protein localization	GO:0034613	122	0.011
organ formation	GO:0048645	3	0.011
lipid transport	GO:0006869	61	0.011
positive regulation of protein modification process	GO:0031401	142	0.011
nitrogen compound transport	GO:0071705	229	0.010
negative regulation of osteoblast differentiation	GO:0045668	2	0.010
cellular nitrogen compound catabolic process	GO:0044270	163	0.010
organelle organization	GO:0006996	266	0.010
cellular response to peptide	GO:1901653	133	0.010
head development	GO:0060322	247	0.010
positive regulation of cell development	GO:0010720	176	0.010
regulation of kinase activity	GO:0043549	117	0.010
single organism behavior	GO:0044708	130	0.010
tissue development	GO:0009888	252	0.010
response to transition metal nanoparticle	GO:1990267	122	0.010
chemical homeostasis	GO:0048878	292	0.010
response to growth factor	GO:0070848	189	0.010
cellular response to cytokine stimulus	GO:0071345	127	0.010
hepaticobiliary system development	GO:0061008	90	0.010
negative regulation of cell death	GO:0060548	229	0.010
neuron neuron synaptic transmission	GO:0007270	60	0.010
response to biotic stimulus	GO:0009607	226	0.010
salivary gland morphogenesis	GO:0007435	1	0.010
response to toxic substance	GO:0009636	133	0.010
single organism catabolic process	GO:0044712	283	0.010
purine nucleoside metabolic process	GO:0042278	169	0.010

Igfbpl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.014
inherited metabolic disorder	DOID:655	0.014
disease of anatomical entity	DOID:7	0.013
nervous system disease	DOID:863	0.013
vascular disease	DOID:178	0.013
cardiovascular system disease	DOID:1287	0.013
disease of cellular proliferation	DOID:14566	0.012
musculoskeletal system disease	DOID:17	0.012
cancer	DOID:162	0.011
organ system cancer	DOID:0050686	0.010

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