Rattus norvegicus

0 known processes

Metap2

methionyl aminopeptidase 2

(Aliases: Amp2,Mnpep,p67)

Metap2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of metabolic processGO:00098923310.251
protein complex biogenesisGO:00702712630.205
negative regulation of apoptotic processGO:00430661810.199
negative regulation of macromolecule biosynthetic processGO:00105581480.195
regulation of nucleic acid templated transcriptionGO:19035063800.188
negative regulation of macromolecule metabolic processGO:00106052600.179
regulation of molecular functionGO:00650093980.172
rna biosynthetic processGO:00327743800.160
regulation of rna biosynthetic processGO:20011413810.158
reproductive processGO:00224143720.158
macromolecular complex subunit organizationGO:00439333390.152
response to peptide hormoneGO:00434342780.133
cellular component biogenesisGO:00440853680.129
protein complex subunit organizationGO:00718223020.127
cellular response to peptideGO:19016531330.124
cellular response to nitrogen compoundGO:19016992100.114
negative regulation of cellular protein metabolic processGO:00322691060.109
negative regulation of biosynthetic processGO:00098901680.108
response to peptideGO:19016522920.104
positive regulation of cell proliferationGO:00082842490.104
organelle organizationGO:00069962660.102
nucleic acid templated transcriptionGO:00976593790.099
single organism reproductive processGO:00447022970.099
negative regulation of cellular metabolic processGO:00313242810.095
mitotic spindle organizationGO:000705220.093
negative regulation of cellular biosynthetic processGO:00313271610.092
protein complex assemblyGO:00064612630.090
negative regulation of programmed cell deathGO:00430691830.089
cell cycleGO:00070491010.084
negative regulation of gene expressionGO:00106291990.082
programmed cell deathGO:00125013920.079
reproductionGO:00000032450.078
regulation of signal transductionGO:00099663180.076
cellular amino acid metabolic processGO:00065201070.075
insulin receptor signaling pathwayGO:0008286240.073
cellular response to endogenous stimulusGO:00714953770.070
regulation of catalytic activityGO:00507903040.070
transcription from rna polymerase ii promoterGO:00063662520.069
rna metabolic processGO:00160704060.067
mitotic cell cycleGO:0000278490.067
macromolecular complex assemblyGO:00650032730.066
mitotic cell cycle processGO:1903047350.066
regulation of programmed cell deathGO:00430673410.064
negative regulation of cellular response to insulin stimulusGO:1900077110.061
regulation of transcription dna templatedGO:00063553740.059
response to temperature stimulusGO:0009266940.058
response to heatGO:0009408600.057
regulation of protein metabolic processGO:00512462890.057
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.054
transcription dna templatedGO:00063513770.052
apoptotic processGO:00069153810.051
anatomical structure morphogenesisGO:00096532980.050
negative regulation of cell deathGO:00605482290.050
multi organism reproductive processGO:00447032620.049
cell cell recognitionGO:000998810.046
enzyme linked receptor protein signaling pathwayGO:00071671160.046
regulation of intracellular signal transductionGO:19025312180.046
negative regulation of protein metabolic processGO:00512481140.044
positive regulation of nucleic acid templated transcriptionGO:19035081970.042
organ morphogenesisGO:0009887750.042
negative regulation of nucleobase containing compound metabolic processGO:00459341530.041
positive regulation of biosynthetic processGO:00098913190.041
regulation of cell proliferationGO:00421273590.041
negative regulation of nucleic acid templated transcriptionGO:19035071170.041
toxin transportGO:190199830.040
positive regulation of rna metabolic processGO:00512542030.040
cytoskeleton organizationGO:00070101110.039
multicellular organismal reproductive processGO:00486092330.039
positive regulation of gene expressionGO:00106282440.039
positive regulation of nitrogen compound metabolic processGO:00511733340.039
multicellular organism reproductionGO:00325042330.038
translationGO:0006412350.038
negative regulation of rna metabolic processGO:00512531230.038
regulation of apoptotic processGO:00429813350.037
defense responseGO:00069521940.036
regulation of cellular amine metabolic processGO:003323880.036
response to oxygen levelsGO:00704822650.036
cellular response to insulin stimulusGO:0032869810.036
cellular component assemblyGO:00226073600.035
regulation of transforming growth factor beta3 productionGO:003291020.035
regulation of hydrolase activityGO:00513361430.034
positive regulation of transportGO:00510502450.033
protein maturationGO:0051604680.033
organic substance catabolic processGO:19015753160.032
single organism intracellular transportGO:19025821660.032
positive regulation of rna biosynthetic processGO:19026801970.032
negative regulation of insulin receptor signaling pathwayGO:0046627100.032
chromosome segregationGO:000705920.032
cellular response to stressGO:00335542690.031
sexual reproductionGO:00199531480.031
single fertilizationGO:000733830.031
proteolysisGO:00065081750.030
cell cycle g1 s phase transitionGO:0044843130.030
cellular component morphogenesisGO:00329891550.030
positive regulation of cellular biosynthetic processGO:00313282950.030
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.030
positive regulation of macromolecule biosynthetic processGO:00105572470.030
negative regulation of nitrogen compound metabolic processGO:00511721610.029
cellular response to peptide hormone stimulusGO:00713751200.029
response to carbohydrateGO:00097431830.029
cellular catabolic processGO:00442482950.028
negative regulation of transcription dna templatedGO:00458921160.028
ion transmembrane transportGO:00342203650.028
intracellular signal transductionGO:00355563140.028
regulation of cellular amino acid metabolic processGO:000652120.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.027
chromatin assembly or disassemblyGO:000633310.027
purine nucleotide biosynthetic processGO:0006164830.027
smad protein complex assemblyGO:000718310.027
regulation of anatomical structure morphogenesisGO:00226031410.026
neuron projection morphogenesisGO:00488121220.026
spindle organizationGO:000705120.026
response to decreased oxygen levelsGO:00362932370.026
peptidyl amino acid modificationGO:00181931260.026
cellular response to hormone stimulusGO:00328702470.025
positive regulation of cellular component organizationGO:00511302000.025
response to hypoxiaGO:00016662310.024
regulation of immune responseGO:0050776550.024
cell cycle phase transitionGO:0044770210.024
regulation of cellular ketone metabolic processGO:0010565270.023
neuron differentiationGO:00301823680.023
protein transportGO:00150311320.023
ribose phosphate metabolic processGO:00196932350.022
regulation of neuron projection developmentGO:00109751610.021
neuron developmentGO:00486662860.021
cell cycle checkpointGO:000007520.021
cation transmembrane transportGO:00986552630.021
response to cytokineGO:00340972150.020
positive regulation of developmental processGO:00510942830.020
synaptic transmissionGO:00072682350.020
nucleobase containing small molecule metabolic processGO:00550863160.019
blood circulationGO:00080151830.019
negative regulation of rna biosynthetic processGO:19026791180.019
response to other organismGO:00517072200.019
cellular amine metabolic processGO:0044106380.019
response to nutrient levelsGO:00316673700.019
negative regulation of signalingGO:00230571570.019
regulation of cellular protein metabolic processGO:00322682670.019
cellular response to oxygen containing compoundGO:19017013860.018
single organism organelle organizationGO:19025891800.018
nucleotide metabolic processGO:00091172790.018
purine containing compound biosynthetic processGO:0072522850.018
regulation of vesicle mediated transportGO:0060627810.018
positive regulation of cellular amine metabolic processGO:003324030.018
regulation of cell cycleGO:0051726730.018
central nervous system developmentGO:00074173110.018
negative regulation of cell communicationGO:00106481580.018
negative regulation of cell cycle phase transitionGO:190198840.017
organophosphate metabolic processGO:00196373700.017
metal ion homeostasisGO:00550651860.017
regulation of membrane potentialGO:00423911100.017
regulation of neurogenesisGO:00507672470.017
cellular homeostasisGO:00197252520.017
cation transportGO:00068123820.017
protein oligomerizationGO:00512591910.017
transforming growth factor beta3 productionGO:003290720.017
positive regulation of response to stimulusGO:00485842850.017
behaviorGO:00076102050.016
response to glucoseGO:00097491360.016
cellular response to organonitrogen compoundGO:00714171970.016
response to corticosteroidGO:00319602350.016
response to growth factorGO:00708481890.016
vesicle mediated transportGO:00161921810.016
cellular protein complex assemblyGO:0043623440.016
secretionGO:00469033070.016
developmental process involved in reproductionGO:00030061590.016
response to estrogenGO:00436272320.016
positive regulation of cell deathGO:00109421840.016
positive regulation of cell projection organizationGO:00313461110.016
gtp catabolic processGO:0006184710.015
cytoskeleton dependent cytokinesisGO:006164020.015
regulation of phosphate metabolic processGO:00192203490.015
regulation of cell developmentGO:00602842630.015
cellular protein catabolic processGO:0044257190.015
cell morphogenesis involved in neuron differentiationGO:00486671060.015
regulation of cellular component organizationGO:00511283680.015
positive regulation of bone mineralizationGO:003050140.015
negative regulation of response to stimulusGO:00485851550.015
negative regulation of signal transductionGO:0009968830.015
tissue developmentGO:00098882520.015
response to nutrientGO:00075842480.015
neurological system processGO:00508772190.015
response to monosaccharideGO:00342841590.015
regulation of cellular response to insulin stimulusGO:1900076160.015
dna packagingGO:000632340.015
response to external biotic stimulusGO:00432072210.015
mitotic dna damage checkpointGO:004477310.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
regulation of protein processingGO:0070613500.014
amine metabolic processGO:0009308380.014
negative regulation of proteolysisGO:0045861410.014
regulation of rna metabolic processGO:00512523910.014
protein phosphorylationGO:00064683450.014
cell morphogenesis involved in differentiationGO:00009041190.014
cellular ketone metabolic processGO:0042180510.014
cell cycle processGO:0022402570.014
spermatogenesisGO:0007283990.014
dendrite developmentGO:0016358720.014
chromatin remodelingGO:000633830.014
carbohydrate derivative metabolic processGO:19011353460.014
regulation of response to external stimulusGO:00321011060.014
wound healingGO:00420601220.014
gamete generationGO:00072761240.013
regulation of phosphorus metabolic processGO:00511743490.013
macromolecule catabolic processGO:0009057580.013
cell projection morphogenesisGO:00488581230.013
oxoacid metabolic processGO:00434362900.013
protein processingGO:0016485680.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
circulatory system processGO:00030131830.013
cellular macromolecular complex assemblyGO:0034622580.013
establishment of protein localizationGO:00451841410.013
male gamete generationGO:0048232990.013
golgi vesicle transportGO:0048193220.013
proteolysis involved in cellular protein catabolic processGO:0051603190.013
dephosphorylationGO:0016311980.013
development of primary sexual characteristicsGO:00451371070.013
response to extracellular stimulusGO:00099913800.013
positive regulation of transcription dna templatedGO:00458931970.013
response to woundingGO:00096112540.013
neuron projection developmentGO:00311752730.012
nucleotide biosynthetic processGO:0009165980.012
inorganic ion transmembrane transportGO:00986602290.012
halogenated hydrocarbon metabolic processGO:004219740.012
mitochondrion organizationGO:0007005350.012
positive regulation of signal transductionGO:00099671750.012
muscle structure developmentGO:0061061870.012
regulation of neuron differentiationGO:00456642080.012
regulation of cell differentiationGO:00455953200.012
positive regulation of molecular functionGO:00440932300.012
regulation of protein modification processGO:00313991940.012
catabolic processGO:00090563510.012
regulation of transferase activityGO:00513381230.012
negative regulation of catalytic activityGO:00430861030.011
negative regulation of intracellular signal transductionGO:1902532380.011
modification dependent macromolecule catabolic processGO:0043632140.011
inflammatory responseGO:00069541500.011
nucleosome organizationGO:003472810.011
muscle organ developmentGO:0007517500.011
cell part morphogenesisGO:00329901230.011
sex differentiationGO:00075481130.011
mapk cascadeGO:00001651400.011
immune responseGO:00069551040.011
regulation of mitotic cell cycle phase transitionGO:1901990110.011
positive regulation of protein metabolic processGO:00512471780.011
regulation of protein phosphorylationGO:00019321830.010
embryonic pattern specificationGO:000988010.010
developmental growthGO:00485891000.010
single organism catabolic processGO:00447122830.010
positive regulation of phosphorus metabolic processGO:00105622620.010
response to insulinGO:00328681330.010
cation homeostasisGO:00550801950.010
regulation of cellular localizationGO:00603412630.010

Metap2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
muscular diseaseDOID:008000000.026
musculoskeletal system diseaseDOID:1700.026