Rattus norvegicus

0 known processes

Hpn

hepsin

Hpn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to inorganic substanceGO:00100353770.224
fibrinolysisGO:004273020.207
cation transmembrane transportGO:00986552630.202
Mouse
response to campGO:0051591910.170
response to extracellular stimulusGO:00099913800.161
positive regulation of macromolecule biosynthetic processGO:00105572470.155
Human
cellular response to oxygen containing compoundGO:19017013860.154
positive regulation of gene expressionGO:00106282440.142
Human Mouse
positive regulation of biosynthetic processGO:00098913190.133
Human
hepatocyte proliferationGO:007257430.124
Human
cellular component assemblyGO:00226073600.123
response to hypoxiaGO:00016662310.123
transmembrane transportGO:00550854120.118
Mouse
homeostatic processGO:00425923310.114
Mouse Rat
response to peptide hormoneGO:00434342780.106
response to retinoic acidGO:0032526630.106
response to nutrient levelsGO:00316673700.103
nucleic acid templated transcriptionGO:00976593790.091
intracellular transportGO:00469071850.085
positive regulation of rna biosynthetic processGO:19026801970.084
Human
rhythmic processGO:00485111560.084
response to peptideGO:19016522920.081
organ regenerationGO:00311001010.081
tissue developmentGO:00098882520.081
Human Mouse
positive regulation of rna metabolic processGO:00512542030.081
Human
cellular response to stressGO:00335542690.080
muscle system processGO:00030121150.079
regulation of nucleic acid templated transcriptionGO:19035063800.078
regulation of cell proliferationGO:00421273590.077
Human
cellular amino acid metabolic processGO:00065201070.077
Mouse
organelle organizationGO:00069962660.074
multi multicellular organism processGO:00447061380.074
response to acid chemicalGO:00011012220.074
rna metabolic processGO:00160704060.073
Human
alpha amino acid metabolic processGO:1901605710.073
single organism intracellular transportGO:19025821660.072
protein complex assemblyGO:00064612630.072
cellular chemical homeostasisGO:00550822470.072
glutathione transportGO:003463520.070
negative regulation of metabolic processGO:00098923310.066
Mouse
regulation of molecular functionGO:00650093980.066
Mouse
reproductive processGO:00224143720.065
regulation of cellular component organizationGO:00511283680.062
Human
cellular response to endogenous stimulusGO:00714953770.062
ensheathment of neuronsGO:0007272400.062
negative regulation of macromolecule metabolic processGO:00106052600.060
cellular response to fluid shear stressGO:007149840.059
cation transportGO:00068123820.059
Mouse
neuron differentiationGO:00301823680.058
positive regulation of blood coagulationGO:003019440.058
oxoacid metabolic processGO:00434362900.058
Mouse
gland developmentGO:00487321550.056
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.056
multicellular organismal reproductive processGO:00486092330.055
regenerationGO:00310991630.055
cellular homeostasisGO:00197252520.054
single organism reproductive processGO:00447022970.054
liver developmentGO:0001889900.053
Human
rna biosynthetic processGO:00327743800.053
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.052
Human Mouse
positive regulation of transcription dna templatedGO:00458931970.052
regulation of multicellular organismal developmentGO:20000263760.051
Human
macromolecular complex assemblyGO:00650032730.051
macromolecular complex subunit organizationGO:00439333390.051
anatomical structure morphogenesisGO:00096532980.050
Human Mouse
protein oligomerizationGO:00512591910.049
regulation of rna biosynthetic processGO:20011413810.049
Human
nucleobase containing small molecule metabolic processGO:00550863160.049
multi organism reproductive processGO:00447032620.048
positive regulation of cellular component organizationGO:00511302000.047
g protein coupled receptor signaling pathwayGO:00071862420.046
activation of jak2 kinase activityGO:004297720.046
regulation of cellular component movementGO:00512701500.045
transcription dna templatedGO:00063513770.045
multicellular organism reproductionGO:00325042330.045
protein complex biogenesisGO:00702712630.045
chemical homeostasisGO:00488782920.044
Mouse Rat
cell morphogenesis involved in differentiationGO:00009041190.044
Human
organic acid metabolic processGO:00060822920.044
Mouse
regulation of transcription dna templatedGO:00063553740.043
response to organophosphorusGO:00466831020.042
negative regulation of multicellular organismal processGO:00512412030.041
Human
carbohydrate derivative metabolic processGO:19011353460.041
synaptic transmissionGO:00072682350.041
gamete generationGO:00072761240.041
positive regulation of response to stimulusGO:00485842850.040
negative regulation of response to stimulusGO:00485851550.040
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.039
response to glucocorticoidGO:00513842230.039
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.038
locomotionGO:00400112370.038
positive regulation of neuron projection developmentGO:0010976990.038
response to decreased oxygen levelsGO:00362932370.038
sexual reproductionGO:00199531480.038
neuron developmentGO:00486662860.036
negative regulation of cellular metabolic processGO:00313242810.036
Mouse
regulation of neuron projection developmentGO:00109751610.036
catabolic processGO:00090563510.036
programmed cell deathGO:00125013920.036
Human
macromolecule localizationGO:00330362520.036
response to molecule of fungal originGO:000223830.036
regulation of rna metabolic processGO:00512523910.036
Human
hepatocyte differentiationGO:007036580.035
epithelial cell proliferation involved in liver morphogenesisGO:007257530.034
Human
carnitine transportGO:001587910.034
circadian rhythmGO:0007623880.034
response to woundingGO:00096112540.034
regulation of anatomical structure morphogenesisGO:00226031410.034
Human
positive regulation of cell migrationGO:0030335960.034
positive regulation of cellular biosynthetic processGO:00313282950.033
Human
protein localizationGO:00081041910.033
response to corticosteroidGO:00319602350.033
regulation of cell projection organizationGO:00313441750.033
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.033
reproductionGO:00000032450.033
response to hexoseGO:00097461440.032
regulation of synaptic transmissionGO:00508041410.032
multicellular organismal signalingGO:0035637440.032
anion transmembrane transportGO:0098656770.032
metal ion homeostasisGO:00550651860.032
Rat
cell migrationGO:00164771970.031
cofactor metabolic processGO:0051186950.031
response to glucoseGO:00097491360.031
regulation of locomotionGO:00400121480.031
ion transmembrane transportGO:00342203650.030
Mouse
cellular cation homeostasisGO:00300031800.030
response to vitaminGO:00332731310.030
response to hyperoxiaGO:0055093450.030
cellular response to peptide hormone stimulusGO:00713751200.030
female pregnancyGO:00075651220.030
cellular response to organonitrogen compoundGO:00714171970.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
Human
cellular response to glucocorticoid stimulusGO:0071385680.029
multicellular organism growthGO:003526410.029
cellular amine metabolic processGO:0044106380.029
Mouse
neurotransmitter transportGO:0006836420.029
cellular component biogenesisGO:00440853680.029
regulation of protein maturationGO:1903317500.029
Human
biological adhesionGO:00226101100.029
response to oxygen levelsGO:00704822650.029
regulation of cell differentiationGO:00455953200.028
Human
regulation of cell developmentGO:00602842630.028
Human
fatty acid transportGO:0015908250.028
proteolysisGO:00065081750.028
Human Rat
positive regulation of cell proliferationGO:00082842490.028
Human
response to estrogenGO:00436272320.028
regulation of protein processingGO:0070613500.028
Human
response to toxic substanceGO:00096361330.028
oxidation reduction processGO:00551143040.028
transcription from rna polymerase ii promoterGO:00063662520.027
single organism cellular localizationGO:19025801020.027
response to transition metal nanoparticleGO:19902671220.027
positive regulation of coagulationGO:005082050.027
response to metal ionGO:00100382530.027
choline transportGO:001587140.027
response to nutrientGO:00075842480.026
organic substance catabolic processGO:19015753160.026
gland morphogenesisGO:0022612120.026
Human
cellular response to abiotic stimulusGO:0071214850.026
regulation of nervous system developmentGO:00519602640.026
negative regulation of gene expressionGO:00106291990.026
negative regulation of cell deathGO:00605482290.026
Human
hepaticobiliary system developmentGO:0061008900.026
Human
tripeptide transportGO:004293920.025
cytoplasmic transportGO:00164821150.025
coenzyme metabolic processGO:0006732860.025
positive regulation of multicellular organismal processGO:00512403870.025
Human
positive regulation of locomotionGO:00400171020.025
cellular response to nitrogen compoundGO:19016992100.025
negative regulation of programmed cell deathGO:00430691830.025
Human
epithelium developmentGO:0060429960.025
Mouse
protein homooligomerizationGO:0051260910.025
purine ribonucleotide metabolic processGO:00091502270.025
cellular response to growth factor stimulusGO:00713631620.025
cation homeostasisGO:00550801950.024
Rat
single organism organelle organizationGO:19025891800.024
cellular response to hormone stimulusGO:00328702470.024
regulation of cell migrationGO:00303341280.024
inflammatory responseGO:00069541500.024
amine metabolic processGO:0009308380.024
Mouse
cell adhesionGO:00071551100.024
lipid transportGO:0006869610.024
liver morphogenesisGO:007257630.024
Human
establishment of protein localizationGO:00451841410.024
positive regulation of cell projection organizationGO:00313461110.024
response to oxidative stressGO:00069791860.024
sensory organ developmentGO:0007423740.024
Mouse
regulation of apoptotic processGO:00429813350.024
Human
axon ensheathmentGO:0008366400.024
positive regulation of wound healingGO:009030360.024
positive regulation of cell motilityGO:2000147970.024
nucleoside phosphate metabolic processGO:00067532830.024
carbohydrate metabolic processGO:00059751300.023
positive regulation of cellular component movementGO:00512721020.023
cellular response to peptideGO:19016531330.023
negative regulation of cell developmentGO:0010721820.023
Human
monovalent inorganic cation transportGO:00156721720.023
Mouse
developmental process involved in reproductionGO:00030061590.023
inorganic ion transmembrane transportGO:00986602290.023
Mouse
central nervous system developmentGO:00074173110.023
regulation of response to external stimulusGO:00321011060.023
cellular response to biotic stimulusGO:0071216590.023
divalent metal ion transportGO:00708381320.023
regulation of response to woundingGO:1903034690.022
glycosyl compound metabolic processGO:19016571820.022
positive regulation of hemostasisGO:190004840.022
regulation of plasminogen activationGO:001075520.022
Human
regulation of stem cell differentiationGO:200073620.022
Human
cellular response to lipopolysaccharideGO:0071222550.022
response to ketoneGO:19016541820.022
cellular response to external stimulusGO:00714961180.022
sequestering of calcium ionGO:005120880.022
single organism biosynthetic processGO:00447113420.022
cellular response to lipidGO:00713962010.022
neuronal action potentialGO:0019228350.022
positive regulation of neurogenesisGO:00507691650.021
negative regulation of molecular functionGO:00440921330.021
Mouse
neurological system processGO:00508772190.021
Mouse Rat
positive regulation of neuron differentiationGO:00456661260.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
inorganic cation transmembrane transportGO:00986622020.021
Mouse
cellular macromolecule localizationGO:00707271220.021
response to starvationGO:0042594590.021
response to monosaccharideGO:00342841590.020
transmission of nerve impulseGO:0019226420.020
nucleotide metabolic processGO:00091172790.020
nucleoside metabolic processGO:00091161790.020
regulation of epithelial cell proliferationGO:0050678490.020
Human
phasic smooth muscle contractionGO:001482130.020
regulation of ion transportGO:00432692450.020
mammary gland developmentGO:0030879380.020
apoptotic processGO:00069153810.020
Human
response to increased oxygen levelsGO:0036296450.020
regulation of programmed cell deathGO:00430673410.020
Human
response to carbohydrateGO:00097431830.020
metal ion transportGO:00300012890.020
Mouse
regulation of phosphorus metabolic processGO:00511743490.020
Mouse
regulation of neurogenesisGO:00507672470.020
hexose metabolic processGO:0019318580.020
response to estradiolGO:00323551640.019
negative regulation of protein metabolic processGO:00512481140.019
amino acid transmembrane transportGO:0003333330.019
amide transportGO:00428861050.019
regulation of fibrinolysisGO:005191720.019
tolerance induction to nonself antigenGO:000246220.019
purine nucleotide metabolic processGO:00061632290.019
growthGO:00400071650.019
Human
regulation of response to stressGO:00801341260.019
immune responseGO:00069551040.019
regulation of cellular localizationGO:00603412630.019
energy derivation by oxidation of organic compoundsGO:0015980460.018
cellular ketone metabolic processGO:0042180510.018
Mouse
negative regulation of transcription dna templatedGO:00458921160.018
sodium ion transmembrane transportGO:0035725670.018
innate immune responseGO:0045087350.018
organ morphogenesisGO:0009887750.018
Human Mouse
small molecule catabolic processGO:0044282590.018
negative regulation of signalingGO:00230571570.018
regulation of neuron differentiationGO:00456642080.018
kidney developmentGO:0001822670.018
regulation of cell motilityGO:20001451310.018
sodium independent organic anion transportGO:004325220.018
protein complex subunit organizationGO:00718223020.018
monocarboxylic acid transportGO:0015718520.018
response to molecule of bacterial originGO:00022371940.018
smooth muscle cell proliferationGO:0048659770.018
sulfur compound metabolic processGO:0006790700.018
toxin transportGO:190199830.018
actin filament based processGO:0030029860.018
negative regulation of cell communicationGO:00106481580.018
spermatogenesisGO:0007283990.017
response to vitamin kGO:003257140.017
negative regulation of protein import into nucleus translocationGO:003315910.017
carboxylic acid metabolic processGO:00197522890.017
Mouse
intracellular signal transductionGO:00355563140.017
regulation of intracellular signal transductionGO:19025312180.017
response to foodGO:0032094270.017
organic anion transportGO:00157111320.017
negative regulation of neurogenesisGO:0050768780.017
neuron projection developmentGO:00311752730.017
reproductive structure developmentGO:00486081280.017
regulation of phosphate metabolic processGO:00192203490.017
Mouse
regulation of cellular amine metabolic processGO:003323880.016
Mouse
response to activityGO:0014823730.016
positive regulation of tolerance induction dependent upon immune responseGO:000265410.016
alpha amino acid catabolic processGO:1901606200.016
cellular component morphogenesisGO:00329891550.016
Human
single organism catabolic processGO:00447122830.016
response to reactive oxygen speciesGO:00003021200.016
positive regulation of immune system processGO:0002684900.016
calcium ion homeostasisGO:00550741620.016
response to growth factorGO:00708481890.016
negative regulation of response to woundingGO:1903035230.016
cellular response to molecule of bacterial originGO:0071219560.016
myelinationGO:0042552390.016
regulation of ovulationGO:006027820.016
anion transportGO:00068201780.016
renal system developmentGO:0072001670.016
regulation of ion transmembrane transportGO:00347651210.016
ribose phosphate metabolic processGO:00196932350.016
negative regulation of cell differentiationGO:0045596990.016
Human
carbohydrate homeostasisGO:0033500750.016
secretionGO:00469033070.016
Rat
glucose metabolic processGO:0006006520.016
regulation of cellular response to stressGO:0080135490.016
cell morphogenesisGO:00009021420.016
Human
monosaccharide metabolic processGO:0005996610.015
positive regulation of tolerance inductionGO:000264510.015
immune system processGO:00023762040.015
coagulationGO:0050817280.015
wound healingGO:00420601220.015
serine family amino acid metabolic processGO:0009069120.015
negative regulation of nervous system developmentGO:0051961790.015
cellular protein localizationGO:00346131220.015
reproductive system developmentGO:00614581280.015
regulation of body fluid levelsGO:0050878900.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
male mating behaviorGO:006017930.015
intracellular protein transportGO:0006886790.015
positive regulation of cell differentiationGO:00455972170.015
positive regulation of response to woundingGO:1903036340.015
positive regulation of hepatocyte differentiationGO:007036820.014
negative regulation of biosynthetic processGO:00098901680.014
positive regulation of phosphorylationGO:00423271770.014
negative regulation of transportGO:00510511360.014
defense responseGO:00069521940.014
regulation of blood coagulationGO:003019390.014
embryonic pattern specificationGO:000988010.014
cellular component movementGO:00069282480.014
protein processingGO:0016485680.014
Human Rat
cellular divalent inorganic cation homeostasisGO:00725031620.014
negative regulation of cellular component organizationGO:0051129830.014
Human
acyl coa metabolic processGO:0006637280.014
regulation of smooth muscle cell proliferationGO:0048660750.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
organophosphate metabolic processGO:00196373700.014
male gamete generationGO:0048232990.014
glucose homeostasisGO:0042593750.014
regulation of establishment of protein localizationGO:0070201690.014
regulation of immune responseGO:0050776550.014
axis specificationGO:000979840.014
divalent inorganic cation transportGO:00725111340.013
positive regulation of cellular amine metabolic processGO:003324030.013
Mouse
neuron deathGO:00709971270.013
negative regulation of fibrinolysisGO:005191820.013
ribonucleotide metabolic processGO:00092592310.013
single organism carbohydrate metabolic processGO:00447231180.013
positive regulation of phosphate metabolic processGO:00459372620.013
regulation of cellular amino acid metabolic processGO:000652120.013
Mouse
reactive oxygen species biosynthetic processGO:190340980.013
quaternary ammonium group transportGO:001569760.013
response to external biotic stimulusGO:00432072210.013
action potentialGO:0001508540.013
maintenance of locationGO:0051235170.013
response to dexamethasoneGO:0071548490.013
cellular response to oxidative stressGO:0034599760.013
cellular response to reactive oxygen speciesGO:0034614550.013
cellular response to corticosteroid stimulusGO:0071384690.013
carboxylic acid catabolic processGO:0046395490.013
cell projection organizationGO:00300303020.013
protein phosphorylationGO:00064683450.013
ovulation cycleGO:0042698670.013
ribonucleoside metabolic processGO:00091191740.013
positive regulation of nervous system developmentGO:00519621780.013
organonitrogen compound catabolic processGO:19015651790.013
monocarboxylic acid biosynthetic processGO:0072330480.013
olfactory learningGO:000835510.013
circulatory system developmentGO:00723591340.012
olfactory behaviorGO:004204820.012
regulation of extracellular matrix constituent secretionGO:000333020.012
reactive oxygen species metabolic processGO:0072593370.012
epithelial cell differentiationGO:0030855710.012
response to biotic stimulusGO:00096072260.012
response to purine containing compoundGO:00140741260.012
positive regulation of reactive oxygen species metabolic processGO:2000379160.012
negative regulation of innate immune responseGO:004582440.012
cellular modified amino acid metabolic processGO:0006575610.012
Mouse
response to fluorideGO:190261730.012
response to insulinGO:00328681330.012
muscle contractionGO:0006936880.012
purine ribonucleoside metabolic processGO:00461281680.012
regulation of cellular ketone metabolic processGO:0010565270.012
Mouse
blood vessel developmentGO:0001568690.012
antibiotic transportGO:004289120.012
endocytosisGO:0006897840.012
developmental growthGO:00485891000.012
negative regulation of cellular biosynthetic processGO:00313271610.012
neuron projection regenerationGO:0031102350.012
acetyl coa metabolic processGO:0006084170.012
regulation of ion homeostasisGO:2000021630.012
Rat
regulation of activation of jak2 kinase activityGO:001053410.012
cellular response to drugGO:0035690300.012
positive regulation of ion transportGO:0043270940.012
regulation of protein metabolic processGO:00512462890.012
Human
regulation of wound healingGO:0061041140.012
gastrulationGO:000736920.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
cardiovascular system developmentGO:00723581340.012
regulation of membrane potentialGO:00423911100.012
positive regulation of intracellular signal transductionGO:19025331380.011
complement activationGO:0006956110.011
cellular response to carbohydrate stimulusGO:0071322720.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
activation of immune responseGO:0002253260.011
ion homeostasisGO:00508012120.011
Rat
response to cytokineGO:00340972150.011
negative regulation of synaptic transmission dopaminergicGO:003222740.011
anterior posterior pattern specificationGO:000995210.011
cellular response to oxygen levelsGO:0071453600.011
glycine metabolic processGO:000654470.011
negative regulation of serine type endopeptidase activityGO:190000410.011
negative regulation of catalytic activityGO:00430861030.011
Mouse
organic acid transportGO:00158491160.011
regulation of signal transductionGO:00099663180.011
regulation of microvillus organizationGO:003253010.011
regulation of defense responseGO:0031347680.011
tolerance induction dependent upon immune responseGO:000246120.011
catenin import into nucleusGO:003541110.011
monoamine transportGO:0015844430.011
cellular response to hexose stimulusGO:0071331650.011
cholesterol homeostasisGO:004263230.011
Mouse
response to fatty acidGO:0070542650.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
Mouse
cellular ion homeostasisGO:00068731840.011
regulation of coagulationGO:0050818110.011
carbohydrate derivative biosynthetic processGO:19011371240.011
localization of cellGO:00516742020.011
cellular response to organic cyclic compoundGO:00714072020.011
mesoderm developmentGO:000749820.011
regulation of purine nucleotide metabolic processGO:19005421150.010
positive regulation of smooth muscle cell migrationGO:0014911270.010
response to ethanolGO:00454711620.010
tissue regenerationGO:0042246360.010
cellular sodium ion homeostasisGO:000688340.010
gonad developmentGO:00084061040.010
positive regulation of protein phosphorylationGO:00019341350.010
regulation of protein localizationGO:0032880810.010
multicellular organismal homeostasisGO:0048871490.010
regulation of reactive oxygen species biosynthetic processGO:190342650.010
lipid storageGO:001991510.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.010
plasminogen activationGO:003163920.010
Human
lipid localizationGO:0010876620.010
cellular metal ion homeostasisGO:00068751720.010
positive regulation of signal transductionGO:00099671750.010
cell projection morphogenesisGO:00488581230.010

Hpn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.020
musculoskeletal system diseaseDOID:1700.020
disease of metabolismDOID:001466700.018
cardiovascular system diseaseDOID:128700.016
vascular diseaseDOID:17800.016
nervous system diseaseDOID:86300.015
bone diseaseDOID:008000100.011
bone development diseaseDOID:008000600.011
connective tissue diseaseDOID:6500.011