Rattus norvegicus

12 known processes

Fen1

flap structure-specific endonuclease 1

(Aliases: FEN-1,MGC94425)

Fen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component organizationGO:00511283680.109
apoptotic processGO:00069153810.100
histone h3 k9 modificationGO:006164720.091
cellular component assemblyGO:00226073600.084
negative regulation of gene expressionGO:00106291990.077
macromolecular complex subunit organizationGO:00439333390.077
carboxylic acid metabolic processGO:00197522890.075
single organism reproductive processGO:00447022970.067
nucleosome organizationGO:003472810.065
regulation of cell proliferationGO:00421273590.064
cellular component biogenesisGO:00440853680.062
protein phosphorylationGO:00064683450.054
positive regulation of nitrogen compound metabolic processGO:00511733340.054
regulation of programmed cell deathGO:00430673410.054
catabolic processGO:00090563510.051
histone serine phosphorylationGO:003540410.050
chromatin assembly or disassemblyGO:000633310.050
response to nutrientGO:00075842480.049
response to growth factorGO:00708481890.048
cellular response to oxygen containing compoundGO:19017013860.047
oxoacid metabolic processGO:00434362900.045
anterior posterior pattern specificationGO:000995210.045
pyrimidine nucleobase metabolic processGO:000620680.042
organelle organizationGO:00069962660.041
negative regulation of metabolic processGO:00098923310.040
alpha amino acid metabolic processGO:1901605710.040
positive regulation of developmental processGO:00510942830.038
cellular catabolic processGO:00442482950.038
cellular amino acid metabolic processGO:00065201070.038
macromolecular complex assemblyGO:00650032730.037
positive regulation of multicellular organismal processGO:00512403870.037
protein complex biogenesisGO:00702712630.036
organic acid metabolic processGO:00060822920.036
regulation of molecular functionGO:00650093980.036
regulation of proteasomal protein catabolic processGO:006113640.036
programmed cell deathGO:00125013920.036
cellular response to endogenous stimulusGO:00714953770.036
regulation of cellular protein metabolic processGO:00322682670.036
anatomical structure morphogenesisGO:00096532980.035
chromosome segregationGO:000705920.035
rna biosynthetic processGO:00327743800.034
dna packagingGO:000632340.034
protein complex assemblyGO:00064612630.034
purine containing compound metabolic processGO:00725212530.034
cellular response to stressGO:00335542690.033
protein localizationGO:00081041910.033
neuron differentiationGO:00301823680.033
regulation of multicellular organismal developmentGO:20000263760.032
macromolecule localizationGO:00330362520.032
response to nutrient levelsGO:00316673700.030
negative regulation of macromolecule metabolic processGO:00106052600.030
regulation of rna biosynthetic processGO:20011413810.030
transcription from rna polymerase ii promoterGO:00063662520.029
protein complex subunit organizationGO:00718223020.029
cytoskeleton dependent cytokinesisGO:006164020.029
regulation of organelle organizationGO:0033043800.028
regenerationGO:00310991630.028
regulation of protein metabolic processGO:00512462890.028
negative regulation of mitotic cell cycle phase transitionGO:190199130.028
cellular modified amino acid biosynthetic processGO:0042398180.028
regulation of protein modification processGO:00313991940.027
chromosome condensationGO:003026130.027
multi organism reproductive processGO:00447032620.027
negative regulation of cell cycle phase transitionGO:190198840.026
chromosome organizationGO:0051276360.026
positive regulation of phosphorus metabolic processGO:00105622620.026
positive regulation of apoptotic processGO:00430651540.026
positive regulation of protein metabolic processGO:00512471780.026
rhythmic processGO:00485111560.025
organic substance catabolic processGO:19015753160.025
regulation of nucleic acid templated transcriptionGO:19035063800.025
positive regulation of cellular biosynthetic processGO:00313282950.025
multicellular organism reproductionGO:00325042330.024
regulation of apoptotic processGO:00429813350.024
reproductive processGO:00224143720.024
single organism biosynthetic processGO:00447113420.024
positive regulation of gene expressionGO:00106282440.024
peptidyl amino acid modificationGO:00181931260.023
axis specificationGO:000979840.023
gonad developmentGO:00084061040.023
cell cycleGO:00070491010.023
regulation of protein phosphorylationGO:00019321830.022
response to extracellular stimulusGO:00099913800.022
negative regulation of microtubule depolymerizationGO:000702630.022
female gonad developmentGO:0008585530.022
tetrahydrofolate metabolic processGO:004665390.022
chromatin modificationGO:0016568330.022
response to estradiolGO:00323551640.022
positive regulation of phosphorylationGO:00423271770.022
regulation of phosphorylationGO:00423252480.022
multicellular organismal reproductive processGO:00486092330.021
positive regulation of cellular protein metabolic processGO:00322701670.021
dephosphorylationGO:0016311980.021
reproductive system developmentGO:00614581280.021
single organism organelle organizationGO:19025891800.021
double strand break repairGO:000630210.020
gland developmentGO:00487321550.020
positive regulation of transcription dna templatedGO:00458931970.020
regulation of cellular amino acid metabolic processGO:000652120.020
nucleobase containing small molecule metabolic processGO:00550863160.020
regulation of phosphorus metabolic processGO:00511743490.020
regulation of transcription from rna polymerase ii promoterGO:00063572340.020
regulation of phosphate metabolic processGO:00192203490.020
regulation of cell developmentGO:00602842630.020
regulation of sister chromatid segregationGO:003304510.020
response to corticosteroidGO:00319602350.020
negative regulation of cellular metabolic processGO:00313242810.019
meiotic cell cycle processGO:190304630.019
organonitrogen compound biosynthetic processGO:19015661670.019
positive regulation of phosphate metabolic processGO:00459372620.019
gamete generationGO:00072761240.019
regulation of rna metabolic processGO:00512523910.019
pyrimidine nucleotide biosynthetic processGO:000622190.019
nucleoside phosphate metabolic processGO:00067532830.018
transcription dna templatedGO:00063513770.018
negative regulation of programmed cell deathGO:00430691830.018
response to glucocorticoidGO:00513842230.018
regulation of cellular ketone metabolic processGO:0010565270.018
intracellular signal transductionGO:00355563140.018
regulation of cell differentiationGO:00455953200.018
embryonic pattern specificationGO:000988010.018
cellular component morphogenesisGO:00329891550.017
pyrimidine containing compound metabolic processGO:0072527200.017
negative regulation of molecular functionGO:00440921330.017
mrna metabolic processGO:0016071200.017
cellular amine metabolic processGO:0044106380.017
regulation of cellular amine metabolic processGO:003323880.017
amine metabolic processGO:0009308380.017
developmental process involved in reproductionGO:00030061590.017
cellular response to growth factor stimulusGO:00713631620.017
cell cycle checkpointGO:000007520.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
regulation of signal transductionGO:00099663180.016
liver developmentGO:0001889900.016
rna metabolic processGO:00160704060.016
regulation of transcription dna templatedGO:00063553740.016
reproductionGO:00000032450.016
regulation of catalytic activityGO:00507903040.016
response to ketoneGO:19016541820.016
positive regulation of protein modification processGO:00314011420.016
central nervous system developmentGO:00074173110.016
positive regulation of rna metabolic processGO:00512542030.016
positive regulation of programmed cell deathGO:00430681570.016
chromatin organizationGO:0006325340.016
regulation of kinase activityGO:00435491170.016
cellular macromolecule localizationGO:00707271220.016
head developmentGO:00603222470.016
neuron developmentGO:00486662860.016
neuron projection developmentGO:00311752730.016
positive regulation of cell proliferationGO:00082842490.016
metaphase plate congressionGO:005131010.015
dna metabolic processGO:0006259960.015
deoxyribonucleoside monophosphate biosynthetic processGO:000915740.015
proteolysisGO:00065081750.015
response to purine containing compoundGO:00140741260.015
tissue developmentGO:00098882520.015
positive regulation of cell differentiationGO:00455972170.015
homeostatic processGO:00425923310.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
nucleoside phosphate biosynthetic processGO:19012931020.015
cytoskeleton organizationGO:00070101110.015
response to oxygen levelsGO:00704822650.015
anion transportGO:00068201780.015
cellular modified amino acid metabolic processGO:0006575610.014
nucleotide metabolic processGO:00091172790.014
positive regulation of neurogenesisGO:00507691650.014
single organism cellular localizationGO:19025801020.014
dna integrity checkpointGO:003157020.014
embryonic axis specificationGO:000057810.014
ovulation cycle processGO:0022602500.014
centrosome cycleGO:000709810.014
cellular component movementGO:00069282480.014
transmembrane transportGO:00550854120.014
sex differentiationGO:00075481130.014
response to hypoxiaGO:00016662310.014
growthGO:00400071650.014
regulation of transferase activityGO:00513381230.014
cellular response to acid chemicalGO:0071229750.013
hepaticobiliary system developmentGO:0061008900.013
response to acid chemicalGO:00011012220.013
organophosphate metabolic processGO:00196373700.013
organic acid biosynthetic processGO:0016053830.013
negative regulation of cell deathGO:00605482290.013
cell projection organizationGO:00300303020.013
microtubule organizing center organizationGO:003102310.013
response to decreased oxygen levelsGO:00362932370.013
cellular protein localizationGO:00346131220.013
organic cyclic compound catabolic processGO:19013611750.013
nucleoside metabolic processGO:00091161790.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
carbohydrate derivative metabolic processGO:19011353460.013
meiosis iGO:000712720.013
negative regulation of cellular component organizationGO:0051129830.013
spindle organizationGO:000705120.013
cellular nitrogen compound catabolic processGO:00442701630.013
pteridine containing compound metabolic processGO:0042558140.013
regulation of neurogenesisGO:00507672470.013
positive regulation of molecular functionGO:00440932300.013
cell morphogenesisGO:00009021420.012
camera type eye morphogenesisGO:004859320.012
response to biotic stimulusGO:00096072260.012
brain developmentGO:00074202470.012
positive regulation of cell deathGO:00109421840.012
cellular ketone metabolic processGO:0042180510.012
lipid metabolic processGO:00066292830.012
nucleotide biosynthetic processGO:0009165980.012
positive regulation of response to stimulusGO:00485842850.012
agingGO:00075682410.012
positive regulation of cell developmentGO:00107201760.011
eye morphogenesisGO:004859240.011
response to peptideGO:19016522920.011
negative regulation of catalytic activityGO:00430861030.011
histone modificationGO:0016570300.011
response to vitaminGO:00332731310.011
cell cycle dna replicationGO:004478610.011
signal transduction by phosphorylationGO:00230141440.011
sexual reproductionGO:00199531480.011
regulation of nervous system developmentGO:00519602640.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
response to external biotic stimulusGO:00432072210.011
macromolecule catabolic processGO:0009057580.011
response to inorganic substanceGO:00100353770.011
response to vitamin eGO:0033197240.011
chromatin remodelingGO:000633830.011
response to radiationGO:00093141370.011
negative regulation of signalingGO:00230571570.011
development of primary sexual characteristicsGO:00451371070.011
centrosome organizationGO:005129710.011
nucleobase containing compound catabolic processGO:00346551520.011
cofactor metabolic processGO:0051186950.011
regulation of protein kinase activityGO:00458591050.011
mitotic spindle organizationGO:000705220.011
spermatogenesisGO:0007283990.011
positive regulation of cellular component organizationGO:00511302000.011
positive regulation of cellular amine metabolic processGO:003324030.011
regulation of microtubule based processGO:0032886140.011
response to monosaccharideGO:00342841590.011
antral ovarian follicle growthGO:000154730.011
deoxyribonucleotide biosynthetic processGO:000926360.011
positive regulation of nervous system developmentGO:00519621780.011
cellular response to lipidGO:00713962010.011
protein dephosphorylationGO:0006470380.011
sister chromatid segregationGO:000081910.010
positive regulation of protein phosphorylationGO:00019341350.010
cellular response to organonitrogen compoundGO:00714171970.010
response to epidermal growth factorGO:0070849180.010
response to molecule of bacterial originGO:00022371940.010
response to ethanolGO:00454711620.010
synaptic transmissionGO:00072682350.010
chemical homeostasisGO:00488782920.010
regulation of ubiquitin protein transferase activityGO:005143810.010
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.010
cell morphogenesis involved in differentiationGO:00009041190.010
renal system developmentGO:0072001670.010
cell cycle processGO:0022402570.010
positive regulation of proteasomal protein catabolic processGO:190180030.010
regulation of response to stressGO:00801341260.010

Fen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.022
cancerDOID:16200.022
organ system cancerDOID:005068600.022
gastrointestinal system cancerDOID:311900.018
intestinal cancerDOID:1015500.018
nervous system diseaseDOID:86300.017
disease of anatomical entityDOID:700.017
colon cancerDOID:21900.015
colorectal cancerDOID:925600.015
large intestine cancerDOID:567200.015
sensory system diseaseDOID:005015500.012
colon carcinomaDOID:152000.012
central nervous system diseaseDOID:33100.010