IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

LOC686539

similar to immunoglobulin superfamily containing leucine-rich repeat

Entrez: 686539
RGD: 1596359
UniProtKB: B1H232

Process Predictions
Disease Predictions

LOC686539 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
response to glucocorticoid	GO:0051384	223	0.167
response to oxygen levels	GO:0070482	265	0.164
response to corticosteroid	GO:0031960	235	0.160
response to mechanical stimulus	GO:0009612	134	0.119
protein oligomerization	GO:0051259	191	0.114
response to camp	GO:0051591	91	0.106
cellular component assembly	GO:0022607	360	0.093
response to peptide	GO:1901652	292	0.093
cellular response to hormone stimulus	GO:0032870	247	0.093
response to organophosphorus	GO:0046683	102	0.091
response to biotic stimulus	GO:0009607	226	0.091
response to estrogen	GO:0043627	232	0.080
response to peptide hormone	GO:0043434	278	0.078
macromolecular complex assembly	GO:0065003	273	0.074
cellular response to vitamin e	GO:0071306	3	0.073
cellular response to lipid	GO:0071396	201	0.068
protein complex biogenesis	GO:0070271	263	0.065
cellular component biogenesis	GO:0044085	368	0.061
reproductive process	GO:0022414	372	0.061
response to other organism	GO:0051707	220	0.055
oxoacid metabolic process	GO:0043436	290	0.053
apoptotic process	GO:0006915	381	0.052
response to decreased oxygen levels	GO:0036293	237	0.051
multi multicellular organism process	GO:0044706	138	0.051
extracellular fibril organization	GO:0043206	1	0.048
response to oxidative stress	GO:0006979	186	0.047
maternal process involved in female pregnancy	GO:0060135	38	0.046
response to acid chemical	GO:0001101	222	0.045
protein homooligomerization	GO:0051260	91	0.045
female pregnancy	GO:0007565	122	0.043
multi organism reproductive process	GO:0044703	262	0.042
chemical homeostasis	GO:0048878	292	0.041
gland development	GO:0048732	155	0.041
carboxylic acid metabolic process	GO:0019752	289	0.040
single organism reproductive process	GO:0044702	297	0.038
protein complex assembly	GO:0006461	263	0.037
proteolysis	GO:0006508	175	0.034
organic acid metabolic process	GO:0006082	292	0.033
cellular response to peptide hormone stimulus	GO:0071375	120	0.032
response to hyperoxia	GO:0055093	45	0.032
circulatory system development	GO:0072359	134	0.032
immune system process	GO:0002376	204	0.031
macromolecular complex subunit organization	GO:0043933	339	0.030
cellular ketone metabolic process	GO:0042180	51	0.030
response to external biotic stimulus	GO:0043207	221	0.030
response to increased oxygen levels	GO:0036296	45	0.030
cellular lipid metabolic process	GO:0044255	208	0.030
cellular response to peptide	GO:1901653	133	0.030
brain development	GO:0007420	247	0.029
protein complex subunit organization	GO:0071822	302	0.029
cellular response to organic cyclic compound	GO:0071407	202	0.029
cellular amine metabolic process	GO:0044106	38	0.029
organic substance catabolic process	GO:1901575	316	0.028
response to hypoxia	GO:0001666	231	0.027
response to radiation	GO:0009314	137	0.026
cellular response to oxygen containing compound	GO:1901701	386	0.026
head development	GO:0060322	247	0.026
locomotion	GO:0040011	237	0.025
positive regulation of signaling	GO:0023056	270	0.025
blood vessel development	GO:0001568	69	0.024
regulation of cellular amine metabolic process	GO:0033238	8	0.024
positive regulation of cellular amine metabolic process	GO:0033240	3	0.023
response to cytokine	GO:0034097	215	0.023
cellular catabolic process	GO:0044248	295	0.023
response to purine containing compound	GO:0014074	126	0.023
regulation of apoptotic process	GO:0042981	335	0.022
positive regulation of multicellular organismal process	GO:0051240	387	0.022
response to retinoic acid	GO:0032526	63	0.022
immune response	GO:0006955	104	0.022
regulation of programmed cell death	GO:0043067	341	0.021
regulation of b cell differentiation	GO:0045577	1	0.021
organ morphogenesis	GO:0009887	75	0.021
regulation of cell proliferation	GO:0042127	359	0.021
cellular amino acid metabolic process	GO:0006520	107	0.021
regulation of cellular ketone metabolic process	GO:0010565	27	0.021
aging	GO:0007568	241	0.021
endochondral ossification	GO:0001958	2	0.021
s shaped body morphogenesis	GO:0072050	2	0.021
response to insulin	GO:0032868	133	0.020
negative regulation of apoptotic process	GO:0043066	181	0.020
regeneration	GO:0031099	163	0.020
response to carbohydrate	GO:0009743	183	0.020
small gtpase mediated signal transduction	GO:0007264	36	0.020
positive regulation of response to stimulus	GO:0048584	285	0.020
cellular component movement	GO:0006928	248	0.019
response to inorganic substance	GO:0010035	377	0.019
homeostatic process	GO:0042592	331	0.019
regulation of anatomical structure morphogenesis	GO:0022603	141	0.018
regulation of locomotion	GO:0040012	148	0.018
response to monosaccharide	GO:0034284	159	0.018
positive regulation of developmental process	GO:0051094	283	0.018
cellular response to nitrogen compound	GO:1901699	210	0.018
protein heterooligomerization	GO:0051291	89	0.018
tissue regeneration	GO:0042246	36	0.017
cellular response to steroid hormone stimulus	GO:0071383	93	0.017
positive regulation of transport	GO:0051050	245	0.017
regulation of cell motility	GO:2000145	131	0.017
response to activity	GO:0014823	73	0.017
positive regulation of synaptic plasticity	GO:0031915	3	0.017
anatomical structure morphogenesis	GO:0009653	298	0.017
intracellular signal transduction	GO:0035556	314	0.016
central nervous system development	GO:0007417	311	0.016
peptide cross linking	GO:0018149	1	0.016
response to reactive oxygen species	GO:0000302	120	0.016
vasculature development	GO:0001944	70	0.016
multicellular organism reproduction	GO:0032504	233	0.015
cellular response to external stimulus	GO:0071496	118	0.015
regulation of immune response	GO:0050776	55	0.015
cellular response to acid chemical	GO:0071229	75	0.015
glomerulus vasculature development	GO:0072012	6	0.015
developmental process involved in reproduction	GO:0003006	159	0.015
amine metabolic process	GO:0009308	38	0.015
extracellular structure organization	GO:0043062	13	0.015
endochondral bone morphogenesis	GO:0060350	7	0.015
cellular response to corticosteroid stimulus	GO:0071384	69	0.015
telencephalon development	GO:0021537	62	0.015
negative regulation of cell proliferation	GO:0008285	119	0.014
cellular response to cytokine stimulus	GO:0071345	127	0.014
skeletal system development	GO:0001501	41	0.014
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
regulation of cellular protein metabolic process	GO:0032268	267	0.014
response to metal ion	GO:0010038	253	0.014
response to estradiol	GO:0032355	164	0.014
positive regulation of phosphate metabolic process	GO:0045937	262	0.014
lipid metabolic process	GO:0006629	283	0.014
response to hydrogen peroxide	GO:0042542	89	0.014
response to glucose	GO:0009749	136	0.013
positive regulation of cell communication	GO:0010647	271	0.013
kidney development	GO:0001822	67	0.013
response to transforming growth factor beta	GO:0071559	46	0.013
cytoskeleton dependent cytokinesis	GO:0061640	2	0.013
lipid modification	GO:0030258	52	0.013
cation homeostasis	GO:0055080	195	0.013
cellular ion homeostasis	GO:0006873	184	0.013
cellular response to organonitrogen compound	GO:0071417	197	0.013
cellular cation homeostasis	GO:0030003	180	0.013
response to low density lipoprotein particle	GO:0055098	4	0.013
positive regulation of cell proliferation	GO:0008284	249	0.012
bmp signaling pathway	GO:0030509	4	0.012
erythrocyte aggregation	GO:0034117	1	0.012
response to lipopolysaccharide	GO:0032496	191	0.012
regulation of system process	GO:0044057	208	0.012
actin cytoskeleton organization	GO:0030036	73	0.012
glial cell differentiation	GO:0010001	65	0.012
response to wounding	GO:0009611	254	0.012
adult locomotory behavior	GO:0008344	4	0.012
multicellular organismal catabolic process	GO:0044243	2	0.012
cellular response to nutrient levels	GO:0031669	60	0.012
metal ion homeostasis	GO:0055065	186	0.012
regulation of cellular localization	GO:0060341	263	0.012
growth	GO:0040007	165	0.012
protein heterotrimerization	GO:0070208	2	0.011
response to bacterium	GO:0009617	200	0.011
positive regulation of programmed cell death	GO:0043068	157	0.011
protein phosphorylation	GO:0006468	345	0.011
single organism biosynthetic process	GO:0044711	342	0.011
vasculogenesis	GO:0001570	3	0.011
ras protein signal transduction	GO:0007265	29	0.011
regulation of phosphorus metabolic process	GO:0051174	349	0.011
nucleotide metabolic process	GO:0009117	279	0.011
metal ion transport	GO:0030001	289	0.011
cardiovascular system development	GO:0072358	134	0.011
response to ethanol	GO:0045471	162	0.011
organ regeneration	GO:0031100	101	0.011
triglyceride homeostasis	GO:0070328	2	0.011
response to alkaloid	GO:0043279	132	0.011
positive regulation of secretion by cell	GO:1903532	128	0.011
response to vitamin a	GO:0033189	36	0.011
positive regulation of cell death	GO:0010942	184	0.010
urogenital system development	GO:0001655	78	0.010
cellular response to extracellular stimulus	GO:0031668	73	0.010
regulation of secretion	GO:0051046	224	0.010
positive regulation of peptide hormone secretion	GO:0090277	50	0.010
positive regulation of apoptotic process	GO:0043065	154	0.010
metanephric s shaped body morphogenesis	GO:0072284	2	0.010
response to lithium ion	GO:0010226	28	0.010
cellular response to stress	GO:0033554	269	0.010
response to molecule of bacterial origin	GO:0002237	194	0.010
positive regulation of cellular biosynthetic process	GO:0031328	295	0.010
negative regulation of cell death	GO:0060548	229	0.010
response to toxic substance	GO:0009636	133	0.010

LOC686539 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.025
retinal disease	DOID:5679	0.025
eye and adnexa disease	DOID:1492	0.025
nervous system disease	DOID:863	0.025
sensory system disease	DOID:0050155	0.025
eye disease	DOID:5614	0.025

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