Rattus norvegicus

0 known processes

Spc25

SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)

(Aliases: RGD1307811,MGC108932,Spbc25)

Spc25 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of chromosome segregationGO:005198310.265
ventricular cardiac muscle cell developmentGO:005501520.173
double strand break repairGO:000630210.167
protein localization to chromosome centromeric regionGO:007145910.155
metaphase anaphase transition of mitotic cell cycleGO:000709110.126
chromosome segregationGO:000705920.123
cell cycle checkpointGO:000007520.122
regulation of cell proliferationGO:00421273590.118
mitotic sister chromatid separationGO:005130610.096
dna packagingGO:000632340.085
response to estrogenGO:00436272320.084
regulation of cellular component organizationGO:00511283680.081
positive regulation of cardiac muscle cell proliferationGO:006004540.081
response to ddtGO:004668010.075
mitotic cell cycle phase transitionGO:0044772200.075
regulation of organelle organizationGO:0033043800.070
organic substance catabolic processGO:19015753160.069
macromolecular complex subunit organizationGO:00439333390.064
regulation of proteasomal protein catabolic processGO:006113640.064
metaphase anaphase transition of cell cycleGO:004478410.062
positive regulation of nitrogen compound metabolic processGO:00511733340.061
cellular component assemblyGO:00226073600.061
multi organism reproductive processGO:00447032620.060
multicellular organismal reproductive processGO:00486092330.060
cellular response to iron iii ionGO:007128330.059
negative regulation of cell cycle phase transitionGO:190198840.057
meiosis iGO:000712720.056
positive regulation of cell proliferationGO:00082842490.055
single organism catabolic processGO:00447122830.055
reproductive processGO:00224143720.054
response to inorganic substanceGO:00100353770.052
single organism organelle organizationGO:19025891800.052
protein phosphorylationGO:00064683450.051
sister chromatid segregationGO:000081910.050
regulation of mitotic sister chromatid segregationGO:003304710.049
regulation of sister chromatid segregationGO:003304510.048
cellular response to oxygen containing compoundGO:19017013860.048
multicellular organism reproductionGO:00325042330.047
negative regulation of mitotic cell cycle phase transitionGO:190199130.046
protein catabolic processGO:0030163300.045
catabolic processGO:00090563510.045
regulation of mitotic sister chromatid separationGO:001096510.045
nucleoside phosphate metabolic processGO:00067532830.043
cellular response to endogenous stimulusGO:00714953770.042
cellular component biogenesisGO:00440853680.042
cell cycleGO:00070491010.042
regulation of molecular functionGO:00650093980.042
histone phosphorylationGO:001657260.041
chromosome separationGO:005130410.041
mitotic cell cycle checkpointGO:000709310.040
positive regulation of multicellular organismal processGO:00512403870.040
cellular response to stressGO:00335542690.039
positive regulation of gene expressionGO:00106282440.039
mitotic cell cycleGO:0000278490.039
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.039
organelle organizationGO:00069962660.038
sexual reproductionGO:00199531480.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
nucleobase containing small molecule metabolic processGO:00550863160.035
negative regulation of metabolic processGO:00098923310.034
cellular catabolic processGO:00442482950.034
anterior posterior pattern specificationGO:000995210.034
positive regulation of cellular biosynthetic processGO:00313282950.034
organophosphate metabolic processGO:00196373700.033
regulation of multicellular organismal developmentGO:20000263760.033
histone serine phosphorylationGO:003540410.033
mitotic cell cycle processGO:1903047350.032
regulation of rna biosynthetic processGO:20011413810.032
regenerationGO:00310991630.031
single organism reproductive processGO:00447022970.031
heterocycle catabolic processGO:00467001670.031
cellular nitrogen compound catabolic processGO:00442701630.031
carbohydrate derivative metabolic processGO:19011353460.031
positive regulation of rna metabolic processGO:00512542030.031
cellular response to organonitrogen compoundGO:00714171970.030
positive regulation of triglyceride metabolic processGO:009020840.030
organic cyclic compound catabolic processGO:19013611750.029
cellular amine metabolic processGO:0044106380.029
mitotic sister chromatid segregationGO:000007010.029
regulation of phosphorus metabolic processGO:00511743490.029
negative regulation of macromolecule metabolic processGO:00106052600.029
protein complex subunit organizationGO:00718223020.028
cellular component movementGO:00069282480.028
nucleotide metabolic processGO:00091172790.028
cell cycle phase transitionGO:0044770210.028
regulation of nuclear cell cycle dna replicationGO:003326210.028
macromolecule catabolic processGO:0009057580.027
regulation of cellular localizationGO:00603412630.027
cellular amino acid metabolic processGO:00065201070.027
cell cycle processGO:0022402570.027
chromosome condensationGO:003026130.027
axis specificationGO:000979840.027
cell cycle g1 s phase transitionGO:0044843130.026
regulation of protein metabolic processGO:00512462890.026
response to decreased oxygen levelsGO:00362932370.026
regulation of cell cycle phase transitionGO:1901987120.026
transcription dna templatedGO:00063513770.026
regulation of apoptotic processGO:00429813350.026
protein complex assemblyGO:00064612630.025
positive regulation of developmental processGO:00510942830.025
negative regulation of apoptotic processGO:00430661810.025
cardiac muscle cell developmentGO:0055013160.024
regulation of protein modification processGO:00313991940.024
dna metabolic processGO:0006259960.024
response to purine containing compoundGO:00140741260.024
reproductionGO:00000032450.024
protein complex biogenesisGO:00702712630.024
macromolecular complex assemblyGO:00650032730.024
purine containing compound metabolic processGO:00725212530.024
cellular process involved in reproduction in multicellular organismGO:0022412350.023
negative regulation of cell deathGO:00605482290.023
regulation of phosphate metabolic processGO:00192203490.023
cellular response to lipidGO:00713962010.023
ribose phosphate metabolic processGO:00196932350.023
cellular protein localizationGO:00346131220.023
cellular response to organic cyclic compoundGO:00714072020.023
aromatic compound catabolic processGO:00194391680.023
positive regulation of biosynthetic processGO:00098913190.023
ribonucleoside triphosphate metabolic processGO:00091991410.023
mitotic spindle organizationGO:000705220.023
negative regulation of chromosome organizationGO:200125110.023
positive regulation of macromolecule biosynthetic processGO:00105572470.023
response to hypoxiaGO:00016662310.023
developmental process involved in reproductionGO:00030061590.023
dna integrity checkpointGO:003157020.023
meiotic cell cycle processGO:190304630.023
negative regulation of cellular metabolic processGO:00313242810.022
purine ribonucleotide metabolic processGO:00091502270.022
mitotic dna damage checkpointGO:004477310.022
apoptotic processGO:00069153810.022
dna conformation changeGO:0071103100.022
tissue developmentGO:00098882520.022
developmental growthGO:00485891000.022
response to metal ionGO:00100382530.022
gamete generationGO:00072761240.022
nucleoside triphosphate metabolic processGO:00091411440.021
single organism biosynthetic processGO:00447113420.021
hindbrain morphogenesisGO:002157520.021
programmed cell deathGO:00125013920.021
g1 s transition of mitotic cell cycleGO:0000082120.021
ventricular cardiac muscle cell differentiationGO:005501220.021
response to transition metal nanoparticleGO:19902671220.021
intracellular signal transductionGO:00355563140.020
response to peptide hormoneGO:00434342780.020
nucleoside monophosphate metabolic processGO:0009123930.020
purine ribonucleoside metabolic processGO:00461281680.020
regulation of cellular protein metabolic processGO:00322682670.020
spindle organizationGO:000705120.020
nucleoside monophosphate catabolic processGO:0009125560.020
negative regulation of molecular functionGO:00440921330.020
negative regulation of programmed cell deathGO:00430691830.019
regulation of phosphorylationGO:00423252480.019
regulation of programmed cell deathGO:00430673410.019
negative regulation of gene expressionGO:00106291990.019
amine metabolic processGO:0009308380.019
head developmentGO:00603222470.019
brain developmentGO:00074202470.019
regulation of heart growthGO:0060420120.019
circulatory system developmentGO:00723591340.019
neuron differentiationGO:00301823680.019
regulation of catabolic processGO:00098941130.019
agingGO:00075682410.019
cell projection organizationGO:00300303020.018
negative regulation of transportGO:00510511360.018
cerebellar purkinje cell layer developmentGO:002168020.018
central nervous system developmentGO:00074173110.018
rna biosynthetic processGO:00327743800.018
regulation of cellular amine metabolic processGO:003323880.018
muscle cell proliferationGO:0033002840.018
response to oxygen levelsGO:00704822650.018
organonitrogen compound catabolic processGO:19015651790.018
regulation of signal transductionGO:00099663180.018
regulation of dna metabolic processGO:0051052600.018
negative regulation of cellular protein metabolic processGO:00322691060.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
purine nucleotide metabolic processGO:00061632290.017
peptidyl amino acid modificationGO:00181931260.017
cellular response to purine containing compoundGO:007141520.017
regulation of mrna 3 end processingGO:003144010.017
rna metabolic processGO:00160704060.017
regulation of nucleic acid templated transcriptionGO:19035063800.017
anatomical structure morphogenesisGO:00096532980.017
cellular ketone metabolic processGO:0042180510.017
purine ribonucleotide catabolic processGO:00091541360.016
mrna metabolic processGO:0016071200.016
negative regulation of microtubule depolymerizationGO:000702630.016
cytokinetic processGO:003250610.016
nucleobase containing compound catabolic processGO:00346551520.016
dephosphorylationGO:0016311980.016
growthGO:00400071650.016
regulation of chromosome organizationGO:003304490.016
nucleotide catabolic processGO:00091661390.016
purine containing compound catabolic processGO:00725231380.016
response to mechanical stimulusGO:00096121340.015
negative regulation of cellular component organizationGO:0051129830.015
cellular macromolecule catabolic processGO:0044265290.015
regulation of cell differentiationGO:00455953200.015
nucleoside phosphate catabolic processGO:19012921400.015
cellular response to dna damage stimulusGO:0006974190.015
cellular response to nitrogen compoundGO:19016992100.015
response to acid chemicalGO:00011012220.015
purine nucleoside metabolic processGO:00422781690.014
proteolysisGO:00065081750.014
negative regulation of response to stimulusGO:00485851550.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243430.014
negative regulation of phosphate metabolic processGO:0045936800.014
male gamete generationGO:0048232990.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
negative regulation of cell divisionGO:005178210.014
response to peptideGO:19016522920.014
nucleoside metabolic processGO:00091161790.014
centrosome organizationGO:005129710.014
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.014
positive regulation of rna biosynthetic processGO:19026801970.014
reproductive structure developmentGO:00486081280.014
purine nucleoside catabolic processGO:00061521240.014
response to toxic substanceGO:00096361330.014
negative regulation of protein metabolic processGO:00512481140.014
regulation of humoral immune response mediated by circulating immunoglobulinGO:000292310.014
neuron developmentGO:00486662860.014
response to ethanolGO:00454711620.014
cellular response to acid chemicalGO:0071229750.013
response to reactive oxygen speciesGO:00003021200.013
regulation of response to stressGO:00801341260.013
negative regulation of cellular biosynthetic processGO:00313271610.013
regulation of cellular amino acid metabolic processGO:000652120.013
regulation of cell cycleGO:0051726730.013
chromatin organizationGO:0006325340.013
cellular macromolecule localizationGO:00707271220.013
maintenance of locationGO:0051235170.013
cell growthGO:00160491040.013
regulation of cell cycle processGO:0010564310.013
positive regulation of lipid catabolic processGO:005099640.013
glycosyl compound metabolic processGO:19016571820.013
reproductive system developmentGO:00614581280.013
cytoskeleton organizationGO:00070101110.013
cellular response to oxidative stressGO:0034599760.012
macromolecule localizationGO:00330362520.012
negative regulation of phosphorus metabolic processGO:0010563800.012
response to woundingGO:00096112540.012
protein localization to chromosomeGO:003450210.012
positive regulation of phosphate metabolic processGO:00459372620.012
cerebellar cortex morphogenesisGO:002169620.012
ubiquitin dependent protein catabolic processGO:0006511140.012
negative regulation of cell communicationGO:00106481580.012
cerebellar purkinje cell differentiationGO:002170210.012
locomotionGO:00400112370.012
regulation of mitotic cell cycle phase transitionGO:1901990110.012
ribonucleoside metabolic processGO:00091191740.012
nucleic acid templated transcriptionGO:00976593790.012
purine nucleoside monophosphate metabolic processGO:0009126840.012
spermatogenesisGO:0007283990.012
positive regulation of synaptic plasticityGO:003191530.012
response to amineGO:0014075460.012
heart developmentGO:0007507720.012
regulation of organ growthGO:0046620130.011
regulation of transcription dna templatedGO:00063553740.011
chromatin modificationGO:0016568330.011
regulation of transferase activityGO:00513381230.011
cellular cation homeostasisGO:00300031800.011
cell cycle dna replicationGO:004478610.011
organophosphate catabolic processGO:00464341480.011
cytoplasmic transportGO:00164821150.011
regulation of protein kinase activityGO:00458591050.011
muscle tissue developmentGO:0060537580.011
regulation of rna metabolic processGO:00512523910.011
response to fatty acidGO:0070542650.011
pyrimidine nucleobase metabolic processGO:000620680.011
positive regulation of dna metabolic processGO:0051054390.011
positive regulation of cellular component organizationGO:00511302000.011
regulation of protein localizationGO:0032880810.011
negative regulation of macromolecule biosynthetic processGO:00105581480.011
endoplasmic reticulum to cytosol transportGO:190351340.011
cell cell signalingGO:00072673350.011
response to estradiolGO:00323551640.011
cellular response to hormone stimulusGO:00328702470.011
cerebellar purkinje cell layer morphogenesisGO:002169210.011
regulation of catalytic activityGO:00507903040.011
ribonucleoside catabolic processGO:00424541260.011
modification dependent protein catabolic processGO:0019941140.011
carboxylic acid metabolic processGO:00197522890.011
chromosome organizationGO:0051276360.010
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
response to organophosphorusGO:00466831020.010
dna replicationGO:0006260370.010
positive regulation of cellular protein metabolic processGO:00322701670.010
ribonucleoside monophosphate metabolic processGO:0009161880.010
response to nutrient levelsGO:00316673700.010
regulation of muscle tissue developmentGO:1901861250.010
regulation of cardiac muscle tissue growthGO:0055021120.010
response to glucocorticoidGO:00513842230.010
development of primary sexual characteristicsGO:00451371070.010
carbohydrate derivative catabolic processGO:19011361470.010
cell morphogenesisGO:00009021420.010
organelle fissionGO:0048285250.010
asymmetric stem cell divisionGO:009872220.010
regulation of striated muscle tissue developmentGO:0016202250.010
cytoskeleton dependent cytokinesisGO:006164020.010

Spc25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
colorectal cancerDOID:925600.014
organ system cancerDOID:005068600.014
disease of cellular proliferationDOID:1456600.014
gastrointestinal system cancerDOID:311900.014
intestinal cancerDOID:1015500.014
colon cancerDOID:21900.014
cancerDOID:16200.014
large intestine cancerDOID:567200.014