Rattus norvegicus

13 known processes

Myl2

myosin, light polypeptide 2, regulatory, cardiac, slow

(Aliases: Mlc2)

Myl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cardiac muscle tissue morphogenesisGO:005500810.927
muscle organ morphogenesisGO:004864410.771
cardiac myofibril assemblyGO:005500310.698
muscle tissue morphogenesisGO:006041510.558
twitch skeletal muscle contractionGO:001472130.477
heart morphogenesisGO:000300730.460
cardiac muscle contractionGO:0060048270.379
sarcoplasmic reticulum calcium ion transportGO:007029680.379
striated muscle contractionGO:0006941440.335
actin mediated cell contractionGO:0070252120.334
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.329
actin myosin filament slidingGO:003327520.299
cellular response to endogenous stimulusGO:00714953770.281
regulation of system processGO:00440572080.281
regulation of muscle system processGO:0090257790.259
purine ribonucleoside monophosphate catabolic processGO:0009169550.244
myosin filament assemblyGO:003103410.226
actin filament based movementGO:0030048160.224
heart developmentGO:0007507720.220
cardiac ventricle developmentGO:000323110.215
anatomical structure formation involved in morphogenesisGO:0048646830.215
negative regulation of molecular functionGO:00440921330.211
cardiac chamber developmentGO:000320510.206
cardiac muscle cell developmentGO:0055013160.196
regulation of molecular functionGO:00650093980.187
response to woundingGO:00096112540.179
anatomical structure morphogenesisGO:00096532980.171
striated muscle tissue developmentGO:0014706580.159
musculoskeletal movementGO:0050881170.157
muscle structure developmentGO:0061061870.155
actin filament based processGO:0030029860.152
response to inorganic substanceGO:00100353770.146
regulation of muscle contractionGO:0006937530.145
multicellular organismal movementGO:0050879170.142
regulation of nucleic acid templated transcriptionGO:19035063800.141
muscle cell developmentGO:0055001260.140
circulatory system processGO:00030131830.139
nucleic acid templated transcriptionGO:00976593790.136
cardiovascular system developmentGO:00723581340.134
negative regulation of metabolic processGO:00098923310.129
tissue developmentGO:00098882520.126
response to heatGO:0009408600.126
positive regulation of transportGO:00510502450.121
sarcomere organizationGO:004521460.120
regenerationGO:00310991630.115
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.109
regulation of striated muscle contractionGO:0006942210.108
positive regulation of developmental processGO:00510942830.106
cellular response to oxygen containing compoundGO:19017013860.099
circulatory system developmentGO:00723591340.099
homeostatic processGO:00425923310.098
cellular response to organic cyclic compoundGO:00714072020.094
muscle contractionGO:0006936880.091
cytoskeleton organizationGO:00070101110.088
muscle organ developmentGO:0007517500.087
developmental inductionGO:003112820.086
negative regulation of cell deathGO:00605482290.086
calcium ion importGO:0070509220.085
actin cytoskeleton organizationGO:0030036730.085
muscle system processGO:00030121150.084
organelle organizationGO:00069962660.084
heart contractionGO:0060047570.083
negative regulation of apoptotic processGO:00430661810.082
protein complex biogenesisGO:00702712630.082
chemical homeostasisGO:00488782920.081
cardiac muscle tissue developmentGO:0048738260.080
cation transportGO:00068123820.078
calcium ion transport from endoplasmic reticulum to cytosolGO:190351440.075
metal ion transportGO:00300012890.074
muscle tissue developmentGO:0060537580.073
myosin filament organizationGO:003103320.073
voluntary skeletal muscle contractionGO:000301030.072
response to growth factorGO:00708481890.071
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.071
regulation of programmed cell deathGO:00430673410.070
striated muscle cell developmentGO:0055002260.068
regulation of actin filament based movementGO:1903115120.065
carbohydrate derivative metabolic processGO:19011353460.063
single organism organelle organizationGO:19025891800.061
muscle cell differentiationGO:0042692520.061
endoplasmic reticulum to cytosol transportGO:190351340.061
regulation of rna biosynthetic processGO:20011413810.058
anterior posterior pattern specificationGO:000995210.058
cell growthGO:00160491040.057
cellular response to nitrogen compoundGO:19016992100.057
atp catabolic processGO:0006200540.056
regulation of cell proliferationGO:00421273590.054
rna biosynthetic processGO:00327743800.053
purine nucleoside monophosphate catabolic processGO:0009128550.052
cellular component movementGO:00069282480.051
regulation of phosphorus metabolic processGO:00511743490.051
regulation of phosphate metabolic processGO:00192203490.050
response to mechanical stimulusGO:00096121340.050
nucleoside monophosphate metabolic processGO:0009123930.050
tissue morphogenesisGO:0048729220.049
purine ribonucleoside monophosphate metabolic processGO:0009167840.047
cellular response to organonitrogen compoundGO:00714171970.047
skeletal muscle tissue developmentGO:0007519310.047
myofibril assemblyGO:003023960.047
organic substance catabolic processGO:19015753160.046
catabolic processGO:00090563510.046
response to nutrient levelsGO:00316673700.045
response to oxidative stressGO:00069791860.045
positive regulation of transcription dna templatedGO:00458931970.044
nucleobase containing small molecule metabolic processGO:00550863160.044
regulation of smooth muscle cell proliferationGO:0048660750.043
positive regulation of nitrogen compound metabolic processGO:00511733340.043
bmp signaling pathwayGO:003050940.043
ventricular cardiac muscle cell differentiationGO:005501220.043
coronary vasculature morphogenesisGO:006097730.042
cellular component assemblyGO:00226073600.042
response to purine containing compoundGO:00140741260.042
positive regulation of rna biosynthetic processGO:19026801970.041
response to monosaccharideGO:00342841590.041
regulation of multicellular organismal developmentGO:20000263760.041
cellular component morphogenesisGO:00329891550.041
cardiac cell developmentGO:0055006160.041
ribonucleotide metabolic processGO:00092592310.041
response to decreased oxygen levelsGO:00362932370.041
heart processGO:0003015570.041
calcium ion transmembrane transportGO:0070588700.040
growthGO:00400071650.040
rna metabolic processGO:00160704060.040
cellular calcium ion homeostasisGO:00068741600.040
cellular protein complex assemblyGO:0043623440.040
positive regulation of gene expressionGO:00106282440.040
positive regulation of rna metabolic processGO:00512542030.039
regulation of transcription dna templatedGO:00063553740.039
positive regulation of molecular functionGO:00440932300.038
purine nucleotide metabolic processGO:00061632290.038
cardiocyte differentiationGO:0035051220.037
positive regulation of cell differentiationGO:00455972170.037
regulation of fat cell proliferationGO:007034410.036
regulation of ion homeostasisGO:2000021630.036
regulation of membrane potentialGO:00423911100.036
macromolecular complex subunit organizationGO:00439333390.036
regulation of blood circulationGO:19035221100.036
regulation of rna metabolic processGO:00512523910.035
cellular ion homeostasisGO:00068731840.035
potassium ion transmembrane transportGO:0071805710.035
response to reactive oxygen speciesGO:00003021200.035
positive regulation of biosynthetic processGO:00098913190.035
blood circulationGO:00080151830.034
cellular component assembly involved in morphogenesisGO:0010927170.034
multicellular organism reproductionGO:00325042330.034
ribonucleoside triphosphate metabolic processGO:00091991410.034
purine containing compound metabolic processGO:00725212530.034
smooth muscle cell proliferationGO:0048659770.034
regulation of cardiac muscle cell contractionGO:0086004110.033
ribose phosphate metabolic processGO:00196932350.033
regulation of organ growthGO:0046620130.033
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.033
cellular response to drugGO:0035690300.033
wound healingGO:00420601220.032
cellular catabolic processGO:00442482950.032
regulation of hormone levelsGO:00108171870.032
enzyme linked receptor protein signaling pathwayGO:00071671160.032
cellular macromolecular complex assemblyGO:0034622580.032
cardiac muscle cell contractionGO:0086003100.032
cellular component biogenesisGO:00440853680.032
macromolecular complex assemblyGO:00650032730.031
regulation of secretion by cellGO:19035302080.031
regulation of secretionGO:00510462240.030
muscle filament slidingGO:003004920.030
negative regulation of cellular metabolic processGO:00313242810.030
negative regulation of gene expressionGO:00106291990.030
nucleotide metabolic processGO:00091172790.029
carbohydrate homeostasisGO:0033500750.029
calcium ion homeostasisGO:00550741620.029
regulation of transmembrane transportGO:00347621220.029
nucleobase containing compound catabolic processGO:00346551520.029
regulation of cell differentiationGO:00455953200.028
negative regulation of programmed cell deathGO:00430691830.028
ribonucleoside monophosphate metabolic processGO:0009161880.028
synapse organizationGO:0050808460.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
epithelial cell differentiationGO:0030855710.028
cellular nitrogen compound catabolic processGO:00442701630.028
regulation of organ formationGO:000315620.028
cellular response to insulin stimulusGO:0032869810.027
positive regulation of cellular component organizationGO:00511302000.027
regulation of catabolic processGO:00098941130.027
nucleoside monophosphate catabolic processGO:0009125560.026
response to hexoseGO:00097461440.026
secretion by cellGO:00329402480.026
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
programmed cell deathGO:00125013920.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
transmembrane transportGO:00550854120.025
regulation of catalytic activityGO:00507903040.025
regulation of signal transductionGO:00099663180.025
response to glucoseGO:00097491360.025
secretionGO:00469033070.024
positive regulation of protein modification processGO:00314011420.024
organophosphate metabolic processGO:00196373700.024
positive regulation of multicellular organismal processGO:00512403870.024
purine nucleoside metabolic processGO:00422781690.024
positive regulation of secretion by cellGO:19035321280.023
regulation of ion transmembrane transportGO:00347651210.023
protein complex assemblyGO:00064612630.023
regulation of heart contractionGO:0008016480.023
response to electrical stimulus involved in regulation of muscle adaptationGO:001487840.023
regulation of heart rateGO:0002027160.023
positive regulation of cell communicationGO:00106472710.023
single organism intracellular transportGO:19025821660.023
apoptotic processGO:00069153810.023
regulation of transporter activityGO:0032409500.023
purine ribonucleotide metabolic processGO:00091502270.023
cellular metal ion homeostasisGO:00068751720.022
neuromuscular processGO:005090520.022
negative regulation of cation channel activityGO:200125860.022
cellular chemical homeostasisGO:00550822470.022
organ inductionGO:000175910.022
sequestering of metal ionGO:005123890.021
regulation of mapk cascadeGO:00434081160.021
regulation of protein metabolic processGO:00512462890.021
muscle cell proliferationGO:0033002840.021
regulation of cellular component organizationGO:00511283680.021
striated muscle cell differentiationGO:0051146390.021
positive regulation of nucleic acid templated transcriptionGO:19035081970.021
response to muscle stretchGO:003599420.021
divalent inorganic cation homeostasisGO:00725071650.020
cellular divalent inorganic cation homeostasisGO:00725031620.020
mesoderm developmentGO:000749820.020
regulation of apoptotic processGO:00429813350.020
cytosolic calcium ion homeostasisGO:00514801400.020
regulation of metal ion transportGO:00109591180.020
nucleoside phosphate metabolic processGO:00067532830.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
neuromuscular synaptic transmissionGO:000727420.020
proteolysisGO:00065081750.020
sequestering of calcium ionGO:005120880.019
maintenance of locationGO:0051235170.019
gamete generationGO:00072761240.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
nucleoside catabolic processGO:00091641260.019
intracellular transportGO:00469071850.019
ventricular cardiac muscle cell action potentialGO:008600520.019
ribonucleoside monophosphate catabolic processGO:0009158550.018
response to campGO:0051591910.018
organophosphate biosynthetic processGO:00904071430.018
multi organism reproductive processGO:00447032620.018
tube developmentGO:0035295890.018
regulation of growthGO:00400081050.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
axis specificationGO:000979840.018
negative regulation of cellular biosynthetic processGO:00313271610.018
negative regulation of ion transmembrane transporter activityGO:0032413120.018
cellular cation homeostasisGO:00300031800.018
cellular response to growth factor stimulusGO:00713631620.018
intracellular signal transductionGO:00355563140.018
actomyosin structure organizationGO:0031032220.018
transcription from rna polymerase ii promoterGO:00063662520.018
angiogenesis involved in coronary vascular morphogenesisGO:006097830.017
skeletal muscle contractionGO:0003009170.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
cell projection morphogenesisGO:00488581230.017
reproductionGO:00000032450.017
organelle assemblyGO:0070925220.017
response to carbohydrateGO:00097431830.017
neuron developmentGO:00486662860.017
epithelium developmentGO:0060429960.017
response to oxygen levelsGO:00704822650.017
glycosyl compound metabolic processGO:19016571820.017
negative regulation of macromolecule metabolic processGO:00106052600.017
negative regulation of phosphorus metabolic processGO:0010563800.017
cellular response to mechanical stimulusGO:0071260480.017
single organism carbohydrate metabolic processGO:00447231180.017
cellular homeostasisGO:00197252520.016
nucleoside triphosphate metabolic processGO:00091411440.016
amine metabolic processGO:0009308380.016
multicellular organismal reproductive processGO:00486092330.016
cell morphogenesis involved in differentiationGO:00009041190.016
reproductive processGO:00224143720.016
response to corticosteroidGO:00319602350.015
response to extracellular stimulusGO:00099913800.015
organic cyclic compound catabolic processGO:19013611750.015
neuron differentiationGO:00301823680.015
positive regulation of catalytic activityGO:00430851840.015
negative regulation of transportGO:00510511360.015
regulation of ion transportGO:00432692450.015
carbohydrate metabolic processGO:00059751300.015
positive regulation of cell proliferationGO:00082842490.015
purine nucleoside monophosphate metabolic processGO:0009126840.015
purine nucleoside triphosphate catabolic processGO:00091461220.015
regulation of homeostatic processGO:00328441010.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
protein complex subunit organizationGO:00718223020.015
signal transduction by phosphorylationGO:00230141440.015
regulation of cellular catabolic processGO:00313291010.015
adult locomotory behaviorGO:000834440.014
inorganic ion transmembrane transportGO:00986602290.014
metal ion homeostasisGO:00550651860.014
response to estrogenGO:00436272320.014
regulation of cellular component biogenesisGO:0044087860.014
response to hypoxiaGO:00016662310.014
organ morphogenesisGO:0009887750.014
single organism reproductive processGO:00447022970.014
cellular amine metabolic processGO:0044106380.014
negative regulation of transporter activityGO:0032410130.014
regulation of cardiac muscle contractionGO:0055117170.014
developmental process involved in reproductionGO:00030061590.014
regulation of cytoskeleton organizationGO:0051493490.014
regulation of actin filament based processGO:0032970420.014
positive regulation of protein metabolic processGO:00512471780.014
transcription dna templatedGO:00063513770.014
purine nucleotide catabolic processGO:00061951360.013
positive regulation of cell developmentGO:00107201760.013
cell cell signalingGO:00072673350.013
gonad developmentGO:00084061040.013
cellular response to peptideGO:19016531330.013
erythrocyte differentiationGO:003021810.013
purine nucleoside catabolic processGO:00061521240.013
cell projection organizationGO:00300303020.013
positive regulation of nervous system developmentGO:00519621780.013
sulfur compound metabolic processGO:0006790700.013
ribonucleoside metabolic processGO:00091191740.013
regulation of cell growthGO:0001558850.013
lipid storageGO:001991510.013
divalent metal ion transportGO:00708381320.013
regulation of cellular localizationGO:00603412630.013
myoblast fusionGO:000752020.013
microtubule based processGO:0007017360.013
regulation of transferase activityGO:00513381230.013
hematopoietic progenitor cell differentiationGO:000224420.013
nucleotide catabolic processGO:00091661390.013
positive regulation of cytoskeleton organizationGO:0051495260.013
regulation of sarcomere organizationGO:006029720.012
nucleoside metabolic processGO:00091161790.012
regulation of canonical wnt signaling pathwayGO:006082840.012
cell morphogenesisGO:00009021420.012
ribonucleoside catabolic processGO:00424541260.012
response to transition metal nanoparticleGO:19902671220.012
slow twitch skeletal muscle fiber contractionGO:003144420.012
response to hydrogen peroxideGO:0042542890.012
glycosyl compound catabolic processGO:19016581260.012
negative regulation of rna biosynthetic processGO:19026791180.012
protein processingGO:0016485680.012
sensory perceptionGO:00076001010.012
regulation of cellular ketone metabolic processGO:0010565270.012
regulation of nervous system developmentGO:00519602640.012
ion transmembrane transportGO:00342203650.012
regulation of transmembrane transporter activityGO:0022898490.012
regulation of ryanodine sensitive calcium release channel activityGO:006031450.012
male gamete generationGO:0048232990.012
ribonucleotide catabolic processGO:00092611360.012
syncytium formationGO:000694940.012
single organism catabolic processGO:00447122830.012
cellular response to stressGO:00335542690.012
synaptic transmissionGO:00072682350.012
cellular response to peptide hormone stimulusGO:00713751200.011
negative regulation of transcription regulatory region dna bindingGO:200067820.011
developmental growthGO:00485891000.011
multicellular organismal signalingGO:0035637440.011
regulation of protein modification processGO:00313991940.011
hormone metabolic processGO:0042445690.011
peptide secretionGO:0002790860.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
protein polymerizationGO:0051258220.011
regulation of sodium ion transmembrane transporter activityGO:200064940.011
regulation of neuron apoptotic processGO:0043523830.011
purine containing compound catabolic processGO:00725231380.011
protein homotetramerizationGO:0051289250.011
response to hyperoxiaGO:0055093450.011
purine ribonucleotide catabolic processGO:00091541360.011
negative regulation of phosphorylationGO:0042326570.011
neuron apoptotic processGO:0051402880.011
synaptic vesicle transportGO:0048489230.011
neurological system processGO:00508772190.011
sexual reproductionGO:00199531480.011
response to phGO:0009268270.011
regulation of intracellular transportGO:0032386650.010
cellular response to alkaloidGO:0071312250.010
regulation of vesicle mediated transportGO:0060627810.010
cytoplasmic transportGO:00164821150.010
ventricular cardiac muscle cell developmentGO:005501520.010
heart growthGO:0060419200.010
tissue regenerationGO:0042246360.010
positive regulation of cellular amine metabolic processGO:003324030.010
central nervous system developmentGO:00074173110.010
positive regulation of cellular protein metabolic processGO:00322701670.010

Myl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.940
cardiomyopathyDOID:005070000.940
disease of anatomical entityDOID:700.940
intrinsic cardiomyopathyDOID:006003600.940
heart diseaseDOID:11400.940
muscular diseaseDOID:008000000.940
cardiovascular system diseaseDOID:128700.940
myopathyDOID:42300.940
muscle tissue diseaseDOID:6600.940
dilated cardiomyopathyDOID:1293000.708
hypertrophic cardiomyopathyDOID:1198400.345
congenital heart diseaseDOID:168200.187
heart septal defectDOID:168100.187
atrial heart septal defectDOID:188200.084
muscular dystrophyDOID:988400.080
nervous system diseaseDOID:86300.018
central nervous system diseaseDOID:33100.018
disease of cellular proliferationDOID:1456600.016
heart conduction diseaseDOID:1027300.011