Rattus norvegicus

7 known processes

Mmel1

membrane metallo-endopeptidase-like 1

(Aliases: NEP2,Mell1,NEPII)

Mmel1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to oxygen containing compoundGO:19017013860.171
positive regulation of nitrogen compound metabolic processGO:00511733340.082
Rat
oxoacid metabolic processGO:00434362900.070
apoptotic processGO:00069153810.069
Rat
positive regulation of cellular biosynthetic processGO:00313282950.065
Rat
carbohydrate derivative metabolic processGO:19011353460.065
Rat
brain developmentGO:00074202470.064
carboxylic acid metabolic processGO:00197522890.063
cellular response to stressGO:00335542690.059
response to hexoseGO:00097461440.056
programmed cell deathGO:00125013920.055
Rat
regulation of apoptotic processGO:00429813350.052
cellular ketone metabolic processGO:0042180510.049
cellular amino acid metabolic processGO:00065201070.049
central nervous system developmentGO:00074173110.048
anatomical structure morphogenesisGO:00096532980.048
regulation of cellular localizationGO:00603412630.047
regulation of ion transportGO:00432692450.047
response to inorganic substanceGO:00100353770.045
Rat
cellular component morphogenesisGO:00329891550.044
inorganic cation transmembrane transportGO:00986622020.043
transmembrane transportGO:00550854120.042
ion transmembrane transportGO:00342203650.042
response to monosaccharideGO:00342841590.042
positive regulation of biosynthetic processGO:00098913190.041
Rat
neuron differentiationGO:00301823680.040
regulation of phosphate metabolic processGO:00192203490.039
Rat
response to acid chemicalGO:00011012220.039
organic acid metabolic processGO:00060822920.038
regulation of hormone levelsGO:00108171870.037
purine containing compound metabolic processGO:00725212530.037
Rat
single organism biosynthetic processGO:00447113420.036
Rat
secretionGO:00469033070.036
glutamate receptor signaling pathwayGO:0007215430.036
positive regulation of molecular functionGO:00440932300.035
regulation of programmed cell deathGO:00430673410.035
response to corticosteroidGO:00319602350.035
response to carbohydrateGO:00097431830.035
transcription dna templatedGO:00063513770.034
regulation of protein metabolic processGO:00512462890.034
protein localizationGO:00081041910.034
regulation of nucleic acid templated transcriptionGO:19035063800.033
hormone transportGO:00099141210.033
macromolecular complex subunit organizationGO:00439333390.033
glycosyl compound metabolic processGO:19016571820.032
regulation of rna biosynthetic processGO:20011413810.032
negative regulation of macromolecule metabolic processGO:00106052600.032
regulation of cellular ketone metabolic processGO:0010565270.032
purine ribonucleotide metabolic processGO:00091502270.032
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.031
catabolic processGO:00090563510.031
positive regulation of rna biosynthetic processGO:19026801970.030
regulation of secretion by cellGO:19035302080.030
peptide hormone secretionGO:0030072840.030
purine nucleotide metabolic processGO:00061632290.030
Rat
response to oxygen levelsGO:00704822650.030
Rat
regulation of secretionGO:00510462240.029
nucleotide metabolic processGO:00091172790.028
Rat
amine metabolic processGO:0009308380.028
head developmentGO:00603222470.028
metal ion transportGO:00300012890.028
positive regulation of protein phosphorylationGO:00019341350.028
multicellular organismal signalingGO:0035637440.028
macromolecular complex assemblyGO:00650032730.028
regulation of transcription dna templatedGO:00063553740.027
regulation of cellular amine metabolic processGO:003323880.027
regulation of molecular functionGO:00650093980.027
response to radiationGO:00093141370.027
nucleic acid templated transcriptionGO:00976593790.027
regulation of peptide transportGO:0090087870.026
neuron projection developmentGO:00311752730.026
nitrogen compound transportGO:00717052290.025
cellular amine metabolic processGO:0044106380.025
wound healingGO:00420601220.025
regulation of cellular amino acid metabolic processGO:000652120.025
negative regulation of cell communicationGO:00106481580.025
protein phosphorylationGO:00064683450.024
positive regulation of macromolecule biosynthetic processGO:00105572470.024
amino acid transportGO:0006865700.024
regulation of phosphorus metabolic processGO:00511743490.024
Rat
peptide transportGO:0015833970.024
anion transportGO:00068201780.024
rna biosynthetic processGO:00327743800.023
regulation of rna metabolic processGO:00512523910.023
organic anion transportGO:00157111320.023
muscle structure developmentGO:0061061870.023
cellular response to organic cyclic compoundGO:00714072020.023
response to peptideGO:19016522920.023
inorganic ion transmembrane transportGO:00986602290.023
nucleobase containing small molecule metabolic processGO:00550863160.023
Rat
homeostatic processGO:00425923310.023
regulation of catalytic activityGO:00507903040.022
protein complex subunit organizationGO:00718223020.022
macromolecule localizationGO:00330362520.022
hormone secretionGO:00468791150.022
negative regulation of metabolic processGO:00098923310.022
reproductive processGO:00224143720.022
positive regulation of protein metabolic processGO:00512471780.022
response to external biotic stimulusGO:00432072210.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
insulin secretionGO:0030073690.021
proteolysisGO:00065081750.021
regulation of insulin secretionGO:0050796650.021
single organism reproductive processGO:00447022970.021
response to decreased oxygen levelsGO:00362932370.021
Rat
ras protein signal transductionGO:0007265290.021
cell morphogenesisGO:00009021420.021
cellular response to lipidGO:00713962010.021
purine ribonucleoside metabolic processGO:00461281680.021
secretion by cellGO:00329402480.021
organic acid transportGO:00158491160.021
single organism catabolic processGO:00447122830.021
positive regulation of signalingGO:00230562700.021
Rat
purine ribonucleoside triphosphate catabolic processGO:00092071220.020
negative regulation of cellular biosynthetic processGO:00313271610.020
single organism organelle organizationGO:19025891800.020
negative regulation of programmed cell deathGO:00430691830.020
sodium ion transportGO:0006814820.020
peptide secretionGO:0002790860.020
rna metabolic processGO:00160704060.020
regulation of peptide hormone secretionGO:0090276800.020
regulation of cellular protein metabolic processGO:00322682670.020
negative regulation of transportGO:00510511360.020
positive regulation of phosphorus metabolic processGO:00105622620.020
Rat
cellular catabolic processGO:00442482950.019
regulation of protein kinase activityGO:00458591050.019
defense responseGO:00069521940.019
positive regulation of protein modification processGO:00314011420.019
positive regulation of nucleobase containing compound metabolic processGO:00459353190.019
Rat
response to ammonium ionGO:0060359710.019
protein oligomerizationGO:00512591910.019
regulation of protein phosphorylationGO:00019321830.019
cell morphogenesis involved in neuron differentiationGO:00486671060.019
positive regulation of transcription dna templatedGO:00458931970.019
positive regulation of cellular amine metabolic processGO:003324030.019
synaptic transmissionGO:00072682350.019
regulation of peptide secretionGO:0002791820.019
amide transportGO:00428861050.019
regulation of cell proliferationGO:00421273590.019
positive regulation of cell proliferationGO:00082842490.019
organic substance catabolic processGO:19015753160.019
positive regulation of transportGO:00510502450.019
negative regulation of cellular metabolic processGO:00313242810.019
regulation of nervous system developmentGO:00519602640.018
positive regulation of rna metabolic processGO:00512542030.018
positive regulation of cellular protein metabolic processGO:00322701670.018
action potentialGO:0001508540.018
agingGO:00075682410.018
response to metal ionGO:00100382530.018
Rat
regulation of catabolic processGO:00098941130.018
neuron developmentGO:00486662860.018
protein complex biogenesisGO:00702712630.018
positive regulation of catalytic activityGO:00430851840.018
negative regulation of gene expressionGO:00106291990.018
establishment of protein localizationGO:00451841410.017
small gtpase mediated signal transductionGO:0007264360.017
cation transportGO:00068123820.017
regulation of phosphorylationGO:00423252480.017
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.017
nucleoside phosphate metabolic processGO:00067532830.017
Rat
positive regulation of phosphorylationGO:00423271770.017
gastrulationGO:000736920.017
cell projection organizationGO:00300303020.017
positive regulation of response to stimulusGO:00485842850.017
Rat
response to peptide hormoneGO:00434342780.017
multicellular organism reproductionGO:00325042330.017
nucleoside metabolic processGO:00091161790.016
cellular response to hexose stimulusGO:0071331650.016
organ regenerationGO:00311001010.016
negative regulation of multicellular organismal processGO:00512412030.016
monovalent inorganic cation transportGO:00156721720.016
intracellular signal transductionGO:00355563140.016
Rat
positive regulation of phosphate metabolic processGO:00459372620.016
Rat
transcription from rna polymerase ii promoterGO:00063662520.016
regulation of membrane potentialGO:00423911100.016
single organism membrane organizationGO:0044802740.016
positive regulation of cellular component organizationGO:00511302000.016
signal releaseGO:00230611450.016
response to extracellular stimulusGO:00099913800.016
negative regulation of apoptotic processGO:00430661810.016
positive regulation of gene expressionGO:00106282440.016
growthGO:00400071650.016
multi organism reproductive processGO:00447032620.016
negative regulation of signalingGO:00230571570.016
regulation of cell developmentGO:00602842630.016
regulation of hydrolase activityGO:00513361430.015
regulation of calcium ion transportGO:0051924770.015
response to glucocorticoidGO:00513842230.015
positive regulation of apoptotic processGO:00430651540.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
regulation of amine transportGO:0051952540.015
nucleoside phosphate catabolic processGO:19012921400.015
positive regulation of nervous system developmentGO:00519621780.015
cellular chemical homeostasisGO:00550822470.015
glucose homeostasisGO:0042593750.015
response to nutrient levelsGO:00316673700.015
positive regulation of cell communicationGO:00106472710.015
Rat
regulation of hormone secretionGO:00468831060.015
nucleoside catabolic processGO:00091641260.014
negative regulation of rna biosynthetic processGO:19026791180.014
negative regulation of biosynthetic processGO:00098901680.014
gliogenesisGO:0042063930.014
response to growth factorGO:00708481890.014
regulation of neurogenesisGO:00507672470.014
regulation of anion transportGO:0044070430.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
axis specificationGO:000979840.014
response to molecule of bacterial originGO:00022371940.014
regulation of protein transportGO:0051223680.014
mapk cascadeGO:00001651400.014
Rat
negative regulation of response to stimulusGO:00485851550.014
multicellular organismal reproductive processGO:00486092330.014
cellular component movementGO:00069282480.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
sensory perception of light stimulusGO:005095330.014
regulation of transferase activityGO:00513381230.013
response to oxidative stressGO:00069791860.013
response to glucoseGO:00097491360.013
positive regulation of nucleotide metabolic processGO:0045981910.013
Rat
cellular response to carbohydrate stimulusGO:0071322720.013
cellular component assemblyGO:00226073600.013
ribonucleotide metabolic processGO:00092592310.013
Rat
organic cyclic compound catabolic processGO:19013611750.013
regulation of intracellular signal transductionGO:19025312180.013
Rat
carboxylic acid transportGO:00469421150.013
regulation of transmembrane transportGO:00347621220.013
cation transmembrane transportGO:00986552630.013
sex differentiationGO:00075481130.013
comma shaped body morphogenesisGO:007204920.013
regulation of protein modification processGO:00313991940.013
metal ion homeostasisGO:00550651860.013
regulation of cell projection organizationGO:00313441750.013
synaptic transmission glutamatergicGO:0035249330.013
cellular response to acid chemicalGO:0071229750.013
nucleoside triphosphate catabolic processGO:00091431230.013
positive regulation of programmed cell deathGO:00430681570.013
multicellular organism growthGO:003526410.013
regulation of nucleotide metabolic processGO:00061401170.013
Rat
regulation of cellular component organizationGO:00511283680.013
protein complex assemblyGO:00064612630.013
single organism cellular localizationGO:19025801020.012
regulation of response to external stimulusGO:00321011060.012
transmission of nerve impulseGO:0019226420.012
carbohydrate homeostasisGO:0033500750.012
neurological system processGO:00508772190.012
response to amineGO:0014075460.012
response to woundingGO:00096112540.012
ribonucleoside metabolic processGO:00091191740.012
regulation of response to stressGO:00801341260.012
striated muscle contractionGO:0006941440.012
development of primary sexual characteristicsGO:00451371070.012
purine nucleoside triphosphate metabolic processGO:00091441410.012
response to biotic stimulusGO:00096072260.012
aromatic compound catabolic processGO:00194391680.012
spindle organizationGO:000705120.012
organophosphate metabolic processGO:00196373700.012
Rat
positive regulation of protein kinase activityGO:0045860730.012
reproductive structure developmentGO:00486081280.012
negative regulation of cellular protein metabolic processGO:00322691060.012
purine ribonucleoside catabolic processGO:00461301240.012
cellular homeostasisGO:00197252520.012
purine nucleotide catabolic processGO:00061951360.012
cell cycleGO:00070491010.012
regulation of neuron deathGO:19012141150.012
negative regulation of neurogenesisGO:0050768780.012
dna metabolic processGO:0006259960.012
purine nucleoside metabolic processGO:00422781690.012
protein transportGO:00150311320.012
reproductive system developmentGO:00614581280.012
chemical homeostasisGO:00488782920.012
eye morphogenesisGO:004859240.012
positive regulation of cell deathGO:00109421840.011
negative regulation of cellular component organizationGO:0051129830.011
cellular response to abiotic stimulusGO:0071214850.011
response to hypoxiaGO:00016662310.011
Rat
male gonad developmentGO:0008584590.011
regulation of purine nucleotide metabolic processGO:19005421150.011
Rat
negative regulation of macromolecule biosynthetic processGO:00105581480.011
regulation of kinase activityGO:00435491170.011
response to bacteriumGO:00096172000.011
cellular component biogenesisGO:00440853680.011
regulation of neuron differentiationGO:00456642080.011
regulation of establishment of protein localizationGO:0070201690.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
cellular response to glucose stimulusGO:0071333650.011
positive regulation of secretion by cellGO:19035321280.011
negative regulation of secretion by cellGO:1903531720.011
response to toxic substanceGO:00096361330.011
male gamete generationGO:0048232990.011
nuclear transportGO:0051169490.011
b cell differentiationGO:003018320.011
gamete generationGO:00072761240.011
positive regulation of catabolic processGO:0009896780.011
response to ethanolGO:00454711620.011
cellular nitrogen compound catabolic processGO:00442701630.011
nucleoside triphosphate metabolic processGO:00091411440.011
heterocycle catabolic processGO:00467001670.011
cellular response to monosaccharide stimulusGO:0071326670.011
negative regulation of cell deathGO:00605482290.011
regulation of protein localizationGO:0032880810.011
regulation of cellular catabolic processGO:00313291010.011
spermatogenesisGO:0007283990.010
detection of visible lightGO:000958430.010
cell morphogenesis involved in differentiationGO:00009041190.010
cell growthGO:00160491040.010
positive regulation of cell differentiationGO:00455972170.010
cell part morphogenesisGO:00329901230.010
negative regulation of cell differentiationGO:0045596990.010
monocarboxylic acid transportGO:0015718520.010
mitotic cell cycleGO:0000278490.010
guanosine containing compound catabolic processGO:1901069710.010
response to cytokineGO:00340972150.010
carbohydrate derivative catabolic processGO:19011361470.010
vesicle mediated transportGO:00161921810.010
negative regulation of protein metabolic processGO:00512481140.010
negative regulation of secretionGO:0051048820.010
neuron apoptotic processGO:0051402880.010

Mmel1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.040
nervous system diseaseDOID:86300.040
eye and adnexa diseaseDOID:149200.032
sensory system diseaseDOID:005015500.032
eye diseaseDOID:561400.031
retinal diseaseDOID:567900.023
retinal degenerationDOID:846600.023