Rattus norvegicus

44 known processes

Ctsh

cathepsin H

Ctsh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.323
carboxylic acid metabolic processGO:00197522890.142
organic substance catabolic processGO:19015753160.138
Human
organic acid metabolic processGO:00060822920.124
response to metal ionGO:00100382530.123
regulation of cell proliferationGO:00421273590.107
Mouse
regulation of body fluid levelsGO:0050878900.096
single organism catabolic processGO:00447122830.091
response to peptide hormoneGO:00434342780.084
response to woundingGO:00096112540.084
monocarboxylic acid metabolic processGO:00327871520.084
response to nutrient levelsGO:00316673700.083
regulation of tolerance induction to nonself antigenGO:000265510.079
response to glucocorticoidGO:00513842230.072
positive regulation of multicellular organismal processGO:00512403870.069
Mouse
negative regulation of response to woundingGO:1903035230.068
negative regulation of multicellular organismal processGO:00512412030.062
response to external biotic stimulusGO:00432072210.062
response to carbohydrateGO:00097431830.061
regenerationGO:00310991630.061
cellular amino acid metabolic processGO:00065201070.060
growthGO:00400071650.060
negative regulation of response to external stimulusGO:0032102370.059
negative regulation of immune system processGO:0002683390.058
single organism reproductive processGO:00447022970.056
multi organism reproductive processGO:00447032620.055
t cell tolerance inductionGO:000251730.054
reproductive processGO:00224143720.052
wound healingGO:00420601220.051
protein maturationGO:0051604680.050
Human Mouse
programmed cell deathGO:00125013920.050
Human Mouse
catabolic processGO:00090563510.050
Human
carbohydrate derivative metabolic processGO:19011353460.050
proteolysisGO:00065081750.050
response to inorganic substanceGO:00100353770.049
response to extracellular stimulusGO:00099913800.048
positive regulation of response to stimulusGO:00485842850.048
Mouse
regulation of multicellular organismal developmentGO:20000263760.047
Mouse
negative regulation of cell deathGO:00605482290.045
Mouse
cellular response to external stimulusGO:00714961180.043
tissue developmentGO:00098882520.043
Mouse
regulation of protein metabolic processGO:00512462890.041
Human Mouse
response to ketoneGO:19016541820.041
cell activationGO:0001775970.041
regulation of hormone levelsGO:00108171870.039
immune system processGO:00023762040.038
Human Mouse
regulation of protein maturationGO:1903317500.038
lipid biosynthetic processGO:00086101280.037
positive regulation of cell proliferationGO:00082842490.036
Mouse
regulation of response to external stimulusGO:00321011060.036
positive regulation of immune responseGO:0050778420.035
agingGO:00075682410.034
regulation of cellular protein metabolic processGO:00322682670.034
Human Mouse
positive regulation of cell projection organizationGO:00313461110.034
secretionGO:00469033070.033
response to peptideGO:19016522920.033
locomotionGO:00400112370.032
Human Mouse
blood coagulationGO:0007596260.032
response to other organismGO:00517072200.031
immune responseGO:00069551040.031
Human Mouse
regulation of cell differentiationGO:00455953200.031
negative regulation of response to stimulusGO:00485851550.031
localization of cellGO:00516742020.031
Human Mouse
peptidyl glutamic acid modificationGO:001820010.030
negative regulation of defense responseGO:0031348190.030
macromolecule catabolic processGO:0009057580.030
behaviorGO:00076102050.030
cellular component movementGO:00069282480.030
Human Mouse
homeostatic processGO:00425923310.030
Human
isoprenoid metabolic processGO:0006720450.029
cellular response to stressGO:00335542690.029
lipid metabolic processGO:00066292830.029
negative regulation of vasculature developmentGO:1901343110.029
negative regulation of protein maturationGO:1903318470.029
nucleobase containing small molecule metabolic processGO:00550863160.028
response to estradiolGO:00323551640.028
defense responseGO:00069521940.028
cell cell signalingGO:00072673350.028
cellular response to endogenous stimulusGO:00714953770.028
cellular amide metabolic processGO:0043603440.028
Human
positive regulation of cell differentiationGO:00455972170.027
positive regulation of nervous system developmentGO:00519621780.027
signal releaseGO:00230611450.026
regulation of neuron differentiationGO:00456642080.026
regulation of immune system processGO:00026821230.026
Human
ion homeostasisGO:00508012120.026
antigen processing and presentation of peptide antigenGO:004800220.026
regulation of catalytic activityGO:00507903040.025
Human Mouse
regulation of neurogenesisGO:00507672470.025
head developmentGO:00603222470.025
positive regulation of developmental processGO:00510942830.025
Mouse
neuron projection developmentGO:00311752730.024
developmental growthGO:00485891000.024
regulation of cellular component movementGO:00512701500.024
Human Mouse
cell projection organizationGO:00300303020.024
regulation of apoptotic processGO:00429813350.024
Human Mouse
response to estrogenGO:00436272320.024
multicellular organismal reproductive processGO:00486092330.024
response to hexoseGO:00097461440.023
reproductive system developmentGO:00614581280.023
response to amineGO:0014075460.023
thyroid hormone generationGO:000659030.023
regulation of epithelial cell proliferationGO:0050678490.022
response to corticosteroidGO:00319602350.022
cellular catabolic processGO:00442482950.022
Human
response to monosaccharideGO:00342841590.022
regulation of immune responseGO:0050776550.022
Human
synaptic transmissionGO:00072682350.021
positive regulation of cellular component movementGO:00512721020.021
Human Mouse
hexose metabolic processGO:0019318580.021
cell motilityGO:00488702020.021
Human Mouse
regulation of hydrolase activityGO:00513361430.021
Human Mouse
epithelial cell differentiationGO:0030855710.020
leukocyte mediated immunityGO:0002443280.020
Mouse
positive regulation of neuron projection developmentGO:0010976990.020
male sex differentiationGO:0046661640.020
immune effector processGO:0002252530.020
Mouse
spermatogenesisGO:0007283990.020
single organism biosynthetic processGO:00447113420.020
response to acid chemicalGO:00011012220.019
Mouse
positive regulation of signal transductionGO:00099671750.019
Mouse
epithelial cell proliferationGO:0050673540.019
regulation of programmed cell deathGO:00430673410.019
Human Mouse
positive regulation of locomotionGO:00400171020.019
Human Mouse
cellular response to alcoholGO:0097306870.019
cellular modified amino acid metabolic processGO:0006575610.019
response to molecule of bacterial originGO:00022371940.019
positive regulation of neurogenesisGO:00507691650.019
monovalent inorganic cation transportGO:00156721720.019
positive regulation of camp metabolic processGO:0030816310.019
negative regulation of peptidase activityGO:0010466380.019
positive regulation of signalingGO:00230562700.018
Mouse
multicellular organism reproductionGO:00325042330.018
positive regulation of tolerance inductionGO:000264510.018
response to starvationGO:0042594590.018
cellular response to lipidGO:00713962010.018
regulation of cell developmentGO:00602842630.018
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051220.018
regulation of locomotionGO:00400121480.018
Human Mouse
response to axon injuryGO:0048678590.018
tissue regenerationGO:0042246360.018
cell migrationGO:00164771970.018
Human Mouse
positive regulation of cellular amine metabolic processGO:003324030.017
regulation of bmp signaling pathwayGO:003051020.017
lymphocyte activationGO:0046649430.017
positive regulation of cellular amino acid metabolic processGO:004576410.017
positive regulation of cell developmentGO:00107201760.017
negative regulation of cell proliferationGO:00082851190.016
carbohydrate derivative catabolic processGO:19011361470.016
response to ethanolGO:00454711620.016
cellular response to iron ion starvationGO:001010610.016
negative regulation of programmed cell deathGO:00430691830.016
Mouse
gland developmentGO:00487321550.016
monosaccharide metabolic processGO:0005996610.016
multi multicellular organism processGO:00447061380.016
response to glucoseGO:00097491360.016
multicellular organismal catabolic processGO:004424320.016
organelle inheritanceGO:004830820.016
response to campGO:0051591910.016
regulation of response to stressGO:00801341260.016
immune system developmentGO:0002520410.016
protein processingGO:0016485680.015
Human Mouse
negative regulation of innate immune responseGO:004582440.015
regulation of phosphorylationGO:00423252480.015
negative regulation of molecular functionGO:00440921330.015
positive regulation of tolerance induction to nonself antigenGO:000265710.015
regulation of nervous system developmentGO:00519602640.015
cellular ketone metabolic processGO:0042180510.015
bmp signaling pathwayGO:003050940.015
regulation of molecular functionGO:00650093980.015
Human Mouse
negative regulation of apoptotic processGO:00430661810.015
Mouse
leukocyte differentiationGO:0002521300.015
macromolecule localizationGO:00330362520.015
regulation of cellular component organizationGO:00511283680.014
reproductionGO:00000032450.014
regulation of immune effector processGO:0002697320.014
ion transmembrane transportGO:00342203650.014
neuron developmentGO:00486662860.014
reproductive structure developmentGO:00486081280.014
positive regulation of cell communicationGO:00106472710.014
Mouse
metal ion transportGO:00300012890.014
cell type specific apoptotic processGO:00972851340.014
male gamete generationGO:0048232990.014
regulation of tolerance induction dependent upon immune responseGO:000265210.014
glycosyl compound metabolic processGO:19016571820.014
response to nutrientGO:00075842480.014
positive regulation of neuron differentiationGO:00456661260.014
dendritic spine developmentGO:0060996200.014
single organism carbohydrate catabolic processGO:0044724400.014
regulation of lipid biosynthetic processGO:0046890380.014
terpenoid metabolic processGO:0006721370.014
negative regulation of protein metabolic processGO:00512481140.014
organic acid biosynthetic processGO:0016053830.014
positive regulation of tolerance induction dependent upon immune responseGO:000265410.014
male gonad developmentGO:0008584590.014
sensory organ developmentGO:0007423740.013
t cell mediated cytotoxicityGO:000191350.013
Mouse
regulation of blood coagulationGO:003019390.013
secretion by cellGO:00329402480.013
coagulationGO:0050817280.013
apoptotic processGO:00069153810.013
Human Mouse
organic cyclic compound catabolic processGO:19013611750.013
cellular component assemblyGO:00226073600.013
regulation of defense responseGO:0031347680.013
chemical homeostasisGO:00488782920.013
Human
positive regulation of cellular component organizationGO:00511302000.013
positive regulation of t cell mediated cytotoxicityGO:000191640.013
regulation of ion transportGO:00432692450.013
regulation of adaptive immune responseGO:000281980.013
cellular amine metabolic processGO:0044106380.012
reactive oxygen species metabolic processGO:0072593370.012
hemostasisGO:0007599260.012
dicarboxylic acid metabolic processGO:0043648420.012
negative regulation of proteolysisGO:0045861410.012
organophosphate metabolic processGO:00196373700.012
regulation of cellular response to growth factor stimulusGO:0090287150.012
regulation of signal transductionGO:00099663180.012
Mouse
tolerance induction dependent upon immune responseGO:000246120.012
cellular response to oxygen containing compoundGO:19017013860.012
negative regulation of catalytic activityGO:00430861030.012
positive regulation of protein metabolic processGO:00512471780.011
Human Mouse
gliogenesisGO:0042063930.011
anatomical structure morphogenesisGO:00096532980.011
Mouse
positive regulation of transportGO:00510502450.011
regulation of cellular amine metabolic processGO:003323880.011
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.011
cellular response to starvationGO:0009267270.011
defense response to virusGO:005160790.011
sex differentiationGO:00075481130.011
regulation of proteolysisGO:0030162660.011
Human Mouse
positive regulation of cellular protein metabolic processGO:00322701670.011
Human Mouse
positive regulation of phosphorylationGO:00423271770.011
response to vitaminGO:00332731310.010
negative regulation of gene expressionGO:00106291990.010
t cell mediated immunityGO:000245670.010
Mouse
negative regulation of natural killer cell mediated immunityGO:000271640.010
regulation of tolerance inductionGO:000264320.010
positive regulation of cell migrationGO:0030335960.010
Human Mouse

Ctsh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.401
disease of metabolismDOID:001466700.401
eye diseaseDOID:561400.216
nervous system diseaseDOID:86300.216
eye and adnexa diseaseDOID:149200.216
disease of anatomical entityDOID:700.216
sensory system diseaseDOID:005015500.216
retinal diseaseDOID:567900.181
retinal degenerationDOID:846600.181
lysosomal storage diseaseDOID:321100.157
brain diseaseDOID:93600.069
central nervous system diseaseDOID:33100.069
age related macular degenerationDOID:1087100.027
degeneration of macula and posterior poleDOID:200700.027
macular degenerationDOID:444800.027
lipid storage diseaseDOID:945500.019
immune system diseaseDOID:291400.013
blood protein diseaseDOID:62000.013
hematopoietic system diseaseDOID:7400.013
integumentary system diseaseDOID:1600.010
skin diseaseDOID:3700.010