Rattus norvegicus

52 known processes

Acot2

acyl-CoA thioesterase 2

(Aliases: Mte1)

Acot2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
fatty acid catabolic processGO:0009062260.993
cellular lipid catabolic processGO:0044242370.951
carboxylic acid metabolic processGO:00197522890.945
organic acid metabolic processGO:00060822920.929
monocarboxylic acid metabolic processGO:00327871520.923
small molecule catabolic processGO:0044282590.920
oxoacid metabolic processGO:00434362900.869
fatty acid metabolic processGO:0006631990.867
lipid metabolic processGO:00066292830.855
monocarboxylic acid catabolic processGO:0072329280.846
fatty acid beta oxidationGO:0006635220.773
lipid oxidationGO:0034440300.716
cellular lipid metabolic processGO:00442552080.698
long chain fatty acid metabolic processGO:0001676320.676
Human Mouse
carboxylic acid catabolic processGO:0046395490.655
fatty acid oxidationGO:0019395290.615
acyl coa metabolic processGO:0006637280.569
coenzyme metabolic processGO:0006732860.458
organic acid catabolic processGO:0016054490.409
cellular catabolic processGO:00442482950.346
oxidation reduction processGO:00551143040.343
positive regulation of lipid catabolic processGO:005099640.300
lipid modificationGO:0030258520.283
acylglycerol metabolic processGO:0006639210.281
response to oxygen levelsGO:00704822650.267
response to peptide hormoneGO:00434342780.261
small molecule biosynthetic processGO:00442831240.260
organic substance catabolic processGO:19015753160.257
cellular response to peptide hormone stimulusGO:00713751200.252
response to extracellular stimulusGO:00099913800.252
sulfur compound metabolic processGO:0006790700.239
neutral lipid metabolic processGO:0006638210.219
response to peptideGO:19016522920.195
single organism biosynthetic processGO:00447113420.177
lipid catabolic processGO:0016042460.173
organic anion transportGO:00157111320.173
monocarboxylic acid transportGO:0015718520.161
gland developmentGO:00487321550.153
Rat
protein complex assemblyGO:00064612630.151
single organism catabolic processGO:00447122830.149
response to nutrientGO:00075842480.147
response to inorganic substanceGO:00100353770.146
triglyceride metabolic processGO:0006641210.143
catabolic processGO:00090563510.140
cellular response to nitrogen compoundGO:19016992100.138
response to monosaccharideGO:00342841590.138
carboxylic acid transportGO:00469421150.137
cellular response to endogenous stimulusGO:00714953770.136
cellular ketone metabolic processGO:0042180510.135
cellular response to organonitrogen compoundGO:00714171970.131
regulation of cellular ketone metabolic processGO:0010565270.128
response to carbohydrateGO:00097431830.128
organic acid transportGO:00158491160.127
regenerationGO:00310991630.123
Rat
lipid biosynthetic processGO:00086101280.121
cellular response to hormone stimulusGO:00328702470.120
cellular amino acid metabolic processGO:00065201070.117
cellular response to peptideGO:19016531330.117
cellular response to oxygen containing compoundGO:19017013860.115
carboxylic acid biosynthetic processGO:0046394830.113
nitrogen compound transportGO:00717052290.112
response to nutrient levelsGO:00316673700.111
response to growth factorGO:00708481890.110
cellular response to lipidGO:00713962010.106
response to decreased oxygen levelsGO:00362932370.105
monosaccharide metabolic processGO:0005996610.102
negative regulation of programmed cell deathGO:00430691830.094
regulation of programmed cell deathGO:00430673410.092
response to metal ionGO:00100382530.089
hormone transportGO:00099141210.087
positive regulation of fatty acid beta oxidationGO:003200040.086
macromolecular complex subunit organizationGO:00439333390.086
response to cytokineGO:00340972150.086
response to acid chemicalGO:00011012220.082
fatty acid biosynthetic processGO:0006633330.080
regulation of cellular localizationGO:00603412630.080
positive regulation of cell differentiationGO:00455972170.079
regulation of fatty acid metabolic processGO:0019217180.079
organ regenerationGO:00311001010.077
Rat
cellular response to insulin stimulusGO:0032869810.077
response to insulinGO:00328681330.076
regulation of secretion by cellGO:19035302080.075
positive regulation of triglyceride biosynthetic processGO:001086740.075
regulation of cellular catabolic processGO:00313291010.074
carnitine metabolic processGO:000943730.072
reproductive processGO:00224143720.072
regulation of secretionGO:00510462240.071
anion transportGO:00068201780.070
negative regulation of apoptotic processGO:00430661810.070
protein complex biogenesisGO:00702712630.069
organic acid biosynthetic processGO:0016053830.069
very long chain fatty acid catabolic processGO:004276020.068
response to hypoxiaGO:00016662310.068
regulation of hormone secretionGO:00468831060.067
regulation of lipid metabolic processGO:0019216680.066
regulation of cellular amino acid metabolic processGO:000652120.066
hepaticobiliary system developmentGO:0061008900.066
Rat
reactive oxygen species metabolic processGO:0072593370.065
establishment of protein localizationGO:00451841410.065
programmed cell deathGO:00125013920.065
secretionGO:00469033070.064
response to oxidative stressGO:00069791860.064
vesicle mediated transportGO:00161921810.063
antral ovarian follicle growthGO:000154730.063
ion transmembrane transportGO:00342203650.063
anion transmembrane transportGO:0098656770.063
cellular response to cytokine stimulusGO:00713451270.062
signal releaseGO:00230611450.061
cellular component assemblyGO:00226073600.059
hexose metabolic processGO:0019318580.058
cellular amine metabolic processGO:0044106380.058
regulation of cellular amine metabolic processGO:003323880.057
linoleic acid metabolic processGO:004365140.056
response to reactive oxygen speciesGO:00003021200.054
response to glucoseGO:00097491360.054
regulation of neurogenesisGO:00507672470.053
regulation of fatty acid beta oxidationGO:003199880.050
regulation of apoptotic processGO:00429813350.050
cellular component biogenesisGO:00440853680.050
protein oligomerizationGO:00512591910.049
glycerolipid metabolic processGO:0046486670.049
response to hexoseGO:00097461440.048
regulation of hormone levelsGO:00108171870.048
glucose metabolic processGO:0006006520.048
negative regulation of cell deathGO:00605482290.047
nucleoside phosphate metabolic processGO:00067532830.047
protein complex subunit organizationGO:00718223020.046
amine metabolic processGO:0009308380.046
secretion by cellGO:00329402480.046
protein phosphorylationGO:00064683450.045
carbohydrate metabolic processGO:00059751300.045
organonitrogen compound biosynthetic processGO:19015661670.044
response to radiationGO:00093141370.044
response to vitaminGO:00332731310.044
response to bacteriumGO:00096172000.044
protein homooligomerizationGO:0051260910.044
response to ethanolGO:00454711620.043
cell part morphogenesisGO:00329901230.043
positive regulation of triglyceride metabolic processGO:009020840.043
regulation of peptide hormone secretionGO:0090276800.043
agingGO:00075682410.042
positive regulation of cellular component organizationGO:00511302000.041
macromolecular complex assemblyGO:00650032730.041
regulation of catabolic processGO:00098941130.041
macromolecule localizationGO:00330362520.041
apoptotic processGO:00069153810.041
amide transportGO:00428861050.040
carbohydrate derivative metabolic processGO:19011353460.040
response to glucocorticoidGO:00513842230.040
response to ketoneGO:19016541820.039
regulation of phosphorus metabolic processGO:00511743490.038
positive regulation of cell developmentGO:00107201760.038
regulation of fatty acid oxidationGO:0046320100.037
response to molecule of bacterial originGO:00022371940.037
response to other organismGO:00517072200.037
intracellular signal transductionGO:00355563140.036
response to fatty acidGO:0070542650.036
thioester metabolic processGO:0035383280.035
cellular response to oxidative stressGO:0034599760.035
response to biotic stimulusGO:00096072260.035
purine containing compound metabolic processGO:00725212530.035
homeostatic processGO:00425923310.035
cell cell signalingGO:00072673350.034
organophosphate biosynthetic processGO:00904071430.034
peptide transportGO:0015833970.034
positive regulation of nervous system developmentGO:00519621780.034
regulation of nervous system developmentGO:00519602640.034
neuron differentiationGO:00301823680.034
regulation of rna metabolic processGO:00512523910.033
regulation of transcription from rna polymerase ii promoterGO:00063572340.033
response to toxic substanceGO:00096361330.033
cofactor metabolic processGO:0051186950.033
regulation of molecular functionGO:00650093980.033
regulation of peptide transportGO:0090087870.033
lymphoid progenitor cell differentiationGO:000232020.033
response to epidermal growth factorGO:0070849180.033
response to lipopolysaccharideGO:00324961910.032
organophosphate metabolic processGO:00196373700.032
fatty acid transmembrane transportGO:190200130.032
defense responseGO:00069521940.032
glycosyl compound metabolic processGO:19016571820.032
immune system processGO:00023762040.032
negative regulation of cellular metabolic processGO:00313242810.032
response to estrogenGO:00436272320.031
regulation of protein modification processGO:00313991940.031
positive regulation of biosynthetic processGO:00098913190.031
peptidyl tyrosine phosphorylationGO:0018108720.031
epithelial cell differentiationGO:0030855710.031
positive regulation of phosphate metabolic processGO:00459372620.031
organic hydroxy compound biosynthetic processGO:1901617510.030
positive regulation of cellular amino acid metabolic processGO:004576410.030
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.030
lipid localizationGO:0010876620.030
single organism reproductive processGO:00447022970.029
regulation of cellular component organizationGO:00511283680.029
positive regulation of signal transductionGO:00099671750.029
regulation of peptide secretionGO:0002791820.029
sequestering of triglycerideGO:003073010.029
response to woundingGO:00096112540.029
developmental process involved in reproductionGO:00030061590.029
cell motilityGO:00488702020.029
regulation of multicellular organismal developmentGO:20000263760.029
negative regulation of transportGO:00510511360.029
multicellular organismal reproductive processGO:00486092330.028
hormone secretionGO:00468791150.028
negative regulation of metabolic processGO:00098923310.028
positive regulation of molecular functionGO:00440932300.028
cellular response to growth factor stimulusGO:00713631620.028
rhythmic processGO:00485111560.028
single organism carbohydrate metabolic processGO:00447231180.028
negative regulation of cell communicationGO:00106481580.028
response to corticosteroidGO:00319602350.028
regulation of protein metabolic processGO:00512462890.027
brain developmentGO:00074202470.027
unsaturated fatty acid metabolic processGO:0033559390.027
peptide secretionGO:0002790860.027
very long chain fatty acid metabolic processGO:000003830.026
negative regulation of multicellular organismal processGO:00512412030.026
endocytosisGO:0006897840.026
lipid storageGO:001991510.026
positive regulation of phosphorus metabolic processGO:00105622620.026
multicellular organism reproductionGO:00325042330.026
cell projection organizationGO:00300303020.026
peptidyl tyrosine modificationGO:0018212720.025
choline transportGO:001587140.025
organelle organizationGO:00069962660.025
negative regulation of cellular biosynthetic processGO:00313271610.025
regulation of cellular protein metabolic processGO:00322682670.025
single organism intracellular transportGO:19025821660.025
positive regulation of cellular amine metabolic processGO:003324030.025
positive regulation of multicellular organismal processGO:00512403870.025
neuron developmentGO:00486662860.025
nucleobase containing small molecule metabolic processGO:00550863160.024
regulation of cell differentiationGO:00455953200.024
cellular component morphogenesisGO:00329891550.024
regulation of protein phosphorylationGO:00019321830.024
cell morphogenesisGO:00009021420.023
negative regulation of gene expressionGO:00106291990.023
protein tetramerizationGO:0051262380.023
purine nucleotide metabolic processGO:00061632290.023
positive regulation of fatty acid oxidationGO:004632160.023
response to purine containing compoundGO:00140741260.023
icosanoid metabolic processGO:0006690380.023
regulation of body fluid levelsGO:0050878900.023
reproductive system developmentGO:00614581280.022
regulation of triglyceride biosynthetic processGO:001086640.022
acetate ester biosynthetic processGO:190062020.022
locomotionGO:00400112370.022
nucleic acid templated transcriptionGO:00976593790.022
positive regulation of protein phosphorylationGO:00019341350.022
neurotransmitter biosynthetic processGO:004213620.022
response to external biotic stimulusGO:00432072210.021
neurotransmitter transportGO:0006836420.021
maintenance of locationGO:0051235170.021
reproductionGO:00000032450.021
amino acid betaine metabolic processGO:000657730.021
positive regulation of intracellular signal transductionGO:19025331380.021
positive regulation of protein metabolic processGO:00512471780.021
acetyl coa metabolic processGO:0006084170.021
lipid transportGO:0006869610.021
positive regulation of phosphorylationGO:00423271770.021
nucleotide metabolic processGO:00091172790.021
positive regulation of cell communicationGO:00106472710.020
positive regulation of neuron differentiationGO:00456661260.020
rna metabolic processGO:00160704060.020
regulation of cell developmentGO:00602842630.020
regulation of tube sizeGO:0035150890.020
amino acid transportGO:0006865700.020
positive regulation of developmental processGO:00510942830.020
regulation of rna biosynthetic processGO:20011413810.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
neuron projection developmentGO:00311752730.019
negative regulation of macromolecule biosynthetic processGO:00105581480.019
single organism organelle organizationGO:19025891800.019
positive regulation of fatty acid metabolic processGO:0045923140.019
neuron projection morphogenesisGO:00488121220.019
negative regulation of nitrogen compound metabolic processGO:00511721610.019
gastrulationGO:000736920.019
cell morphogenesis involved in differentiationGO:00009041190.019
peptide hormone secretionGO:0030072840.019
single organism behaviorGO:00447081300.019
rna biosynthetic processGO:00327743800.019
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.019
mesoderm morphogenesisGO:004833210.019
transcription from rna polymerase ii promoterGO:00063662520.019
regulation of locomotionGO:00400121480.019
insulin secretionGO:0030073690.018
negative regulation of macromolecule metabolic processGO:00106052600.018
phosphatidylethanolamine metabolic processGO:004633710.018
purine ribonucleotide metabolic processGO:00091502270.018
eye morphogenesisGO:004859240.018
negative regulation of rna metabolic processGO:00512531230.018
regulation of vesicle mediated transportGO:0060627810.018
regulation of phosphate metabolic processGO:00192203490.018
naphthalene metabolic processGO:001893120.018
cellular response to reactive oxygen speciesGO:0034614550.018
cellular response to lipopolysaccharideGO:0071222550.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
regulation of signal transductionGO:00099663180.018
positive regulation of neurogenesisGO:00507691650.018
regulation of intracellular signal transductionGO:19025312180.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
b cell differentiationGO:003018320.017
ras protein signal transductionGO:0007265290.017
kidney developmentGO:0001822670.017
negative regulation of biosynthetic processGO:00098901680.017
head developmentGO:00603222470.017
chemical homeostasisGO:00488782920.017
ribonucleotide metabolic processGO:00092592310.017
cellular response to acid chemicalGO:0071229750.017
anatomical structure morphogenesisGO:00096532980.017
localization of cellGO:00516742020.017
negative regulation of developmental processGO:00510931250.017
cdp choline pathwayGO:000665730.017
negative regulation of secretionGO:0051048820.017
response to vitamin eGO:0033197240.017
central nervous system developmentGO:00074173110.017
alcohol metabolic processGO:0006066770.017
multicellular organism growthGO:003526410.017
negative regulation of signalingGO:00230571570.016
enzyme linked receptor protein signaling pathwayGO:00071671160.016
dendrite developmentGO:0016358720.016
cognitionGO:0050890920.016
development of primary sexual characteristicsGO:00451371070.016
regulation of membrane potentialGO:00423911100.016
cellular response to stressGO:00335542690.016
regulation of anatomical structure sizeGO:00900661350.016
innate immune responseGO:0045087350.016
response to estradiolGO:00323551640.016
negative regulation of response to stimulusGO:00485851550.015
regulation of cell projection organizationGO:00313441750.015
intracellular transportGO:00469071850.015
fatty acid transportGO:0015908250.015
positive regulation of gene expressionGO:00106282440.015
regulation of phosphorylationGO:00423252480.015
positive regulation of response to stimulusGO:00485842850.015
positive regulation of protein modification processGO:00314011420.015
transmembrane transportGO:00550854120.015
ovulation cycle processGO:0022602500.015
positive regulation of secretion by cellGO:19035321280.015
positive regulation of transportGO:00510502450.015
long chain fatty acid transportGO:0015909140.015
response to mechanical stimulusGO:00096121340.015
long chain fatty acid importGO:004453910.015
organic hydroxy compound metabolic processGO:19016151150.015
regulation of fat cell differentiationGO:004559830.015
amino acid transmembrane transportGO:0003333330.015
regulation of lipid biosynthetic processGO:0046890380.015
pyridine containing compound metabolic processGO:0072524320.015
regulation of anatomical structure morphogenesisGO:00226031410.015
response to campGO:0051591910.015
positive regulation of catabolic processGO:0009896780.015
regulation of lipid catabolic processGO:0050994120.015
growthGO:00400071650.014
female gonad developmentGO:0008585530.014
behaviorGO:00076102050.014
cellular response to organic cyclic compoundGO:00714072020.014
positive regulation of hormone secretionGO:0046887650.014
insulin receptor signaling pathwayGO:0008286240.014
negative regulation of organ growthGO:004662130.014
axis specificationGO:000979840.014
camera type eye morphogenesisGO:004859320.014
protein secretionGO:0009306340.014
regulation of neuron differentiationGO:00456642080.014
small gtpase mediated signal transductionGO:0007264360.014
heart morphogenesisGO:000300730.013
organic cyclic compound catabolic processGO:19013611750.013
positive regulation of cellular biosynthetic processGO:00313282950.013
regulation of jak stat cascadeGO:0046425210.013
cellular cation homeostasisGO:00300031800.013
reproductive structure developmentGO:00486081280.013
multi organism reproductive processGO:00447032620.013
membrane organizationGO:0061024940.013
regulation of organelle organizationGO:0033043800.013
peptidyl amino acid modificationGO:00181931260.013
regulation of catalytic activityGO:00507903040.013
embryonic pattern specificationGO:000988010.013
sexual reproductionGO:00199531480.013
female pregnancyGO:00075651220.013
epithelium developmentGO:0060429960.013
cellular chemical homeostasisGO:00550822470.013
ribose phosphate metabolic processGO:00196932350.013
regulation of insulin secretionGO:0050796650.013
positive regulation of signalingGO:00230562700.013
response to hydrogen peroxideGO:0042542890.013
regulation of transferase activityGO:00513381230.013
gamete generationGO:00072761240.013
cytoplasmic transportGO:00164821150.013
sex differentiationGO:00075481130.013
ovulation cycleGO:0042698670.013
activation of jak2 kinase activityGO:004297720.013
response to testosteroneGO:0033574550.013
positive regulation of cell projection organizationGO:00313461110.012
regulation of system processGO:00440572080.012
anterior posterior pattern specificationGO:000995210.012
response to coldGO:0009409290.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
regulation of phagocytosis engulfmentGO:006009940.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
cellular component movementGO:00069282480.012
negative regulation of transcription dna templatedGO:00458921160.012
dephosphorylationGO:0016311980.012
neuronal action potentialGO:0019228350.012
monocarboxylic acid biosynthetic processGO:0072330480.012
cell fate determinationGO:000170920.012
cellular homeostasisGO:00197252520.012
regulation of proteasomal protein catabolic processGO:006113640.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
response to starvationGO:0042594590.012
reactive oxygen species biosynthetic processGO:190340980.012
immune responseGO:00069551040.012
cell cell junction organizationGO:0045216200.012
chlorinated hydrocarbon metabolic processGO:004219640.011
fatty acid derivative metabolic processGO:1901568380.011
response to activityGO:0014823730.011
response to alkaloidGO:00432791320.011
regulation of transcription dna templatedGO:00063553740.011
cellular amide metabolic processGO:0043603440.011
positive regulation of nucleobase containing compound metabolic processGO:00459353190.011
positive regulation of nitrogen compound metabolic processGO:00511733340.011
gonad developmentGO:00084061040.011
neurological system processGO:00508772190.011
regulation of gluconeogenesisGO:000611140.011
regulation of cellular carbohydrate metabolic processGO:0010675390.011
cellular response to nutrient levelsGO:0031669600.011
cellular nitrogen compound catabolic processGO:00442701630.011
developmental growthGO:00485891000.011
vascular process in circulatory systemGO:0003018960.011
cell junction organizationGO:0034330210.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.011
defense response to gram negative bacteriumGO:005082930.011
chromosome segregationGO:000705920.011
response to cadmium ionGO:0046686350.011
regulation of organic acid transportGO:0032890350.011
positive regulation of transferase activityGO:0051347810.011
vasculogenesisGO:000157030.011
peptide metabolic processGO:0006518320.011
negative regulation of signal transductionGO:0009968830.011
tissue developmentGO:00098882520.011
organ formationGO:004864530.011
regulation of protein kinase activityGO:00458591050.011
positive regulation of lipid metabolic processGO:0045834330.011
inflammatory responseGO:00069541500.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
positive regulation of rna metabolic processGO:00512542030.010
branched chain amino acid metabolic processGO:000908140.010
positive regulation of neuron projection developmentGO:0010976990.010
cell cycle checkpointGO:000007520.010
retinoic acid receptor signaling pathwayGO:004838470.010
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.010
regulation of homeostatic processGO:00328441010.010
response to amino acidGO:0043200750.010
arachidonic acid metabolic processGO:0019369200.010
toxin transportGO:190199830.010
regulation of response to external stimulusGO:00321011060.010
protein localizationGO:00081041910.010
regulation of neurotransmitter levelsGO:0001505420.010
cellular response to xenobiotic stimulusGO:0071466190.010
positive regulation of cellular catabolic processGO:0031331710.010
transcription dna templatedGO:00063513770.010

Acot2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.079
disease of anatomical entityDOID:700.079
muscle tissue diseaseDOID:6600.079
muscular diseaseDOID:008000000.079
myopathyDOID:42300.079
nervous system diseaseDOID:86300.050
muscular dystrophyDOID:988400.042
disease of metabolismDOID:001466700.034
acquired metabolic diseaseDOID:006015800.023
overnutritionDOID:65400.023
nutrition diseaseDOID:37400.023
sensory system diseaseDOID:005015500.023
central nervous system diseaseDOID:33100.023
inherited metabolic disorderDOID:65500.015
obesityDOID:997000.014
cardiovascular system diseaseDOID:128700.010