| atp metabolic process | GO:0046034 | 72 | 0.906 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 84 | 0.795 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 93 | 0.775 | |
| electron transport chain | GO:0022900 | 5 | 0.711 | |
| tetrapyrrole metabolic process | GO:0033013 | 11 | 0.705 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.680 | |
| oxidative phosphorylation | GO:0006119 | 4 | 0.627 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.547 | |
| porphyrin containing compound biosynthetic process | GO:0006779 | 6 | 0.509 | |
| atp synthesis coupled electron transport | GO:0042773 | 2 | 0.488 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 144 | 0.487 | |
| neurotransmitter uptake | GO:0001504 | 3 | 0.479 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.462 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.450 | |
| oxidation reduction process | GO:0055114 | 304 | 0.431 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 88 | 0.419 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.413 | |
| thioester biosynthetic process | GO:0035384 | 7 | 0.404 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.398 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 141 | 0.395 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.374 | |
| pigment biosynthetic process | GO:0046148 | 4 | 0.349 | |
| cellular respiration | GO:0045333 | 21 | 0.337 | |
| coenzyme metabolic process | GO:0006732 | 86 | 0.313 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.288 | |
| cofactor biosynthetic process | GO:0051188 | 28 | 0.288 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 140 | 0.283 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.275 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.274 | |
| cofactor metabolic process | GO:0051186 | 95 | 0.273 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.268 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.267 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.264 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.244 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.218 | |
| transmembrane transport | GO:0055085 | 412 | 0.215 | |
| porphyrin containing compound metabolic process | GO:0006778 | 8 | 0.213 | |
| ribonucleotide metabolic process | GO:0009259 | 231 | 0.206 | |
| positive regulation of atp biosynthetic process | GO:2001171 | 2 | 0.199 | |
| acetyl coa metabolic process | GO:0006084 | 17 | 0.193 | |
| energy derivation by oxidation of organic compounds | GO:0015980 | 46 | 0.182 | |
| negative regulation of hydrogen peroxide biosynthetic process | GO:0010730 | 2 | 0.181 | |
| mitochondrial calcium ion transport | GO:0006851 | 2 | 0.178 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.160 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 84 | 0.159 | |
| acetyl coa biosynthetic process from pyruvate | GO:0006086 | 5 | 0.157 | |
| purine nucleoside biosynthetic process | GO:0042451 | 21 | 0.150 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.136 | |
| metal ion transport | GO:0030001 | 289 | 0.128 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.113 | |
| mitochondrial calcium ion homeostasis | GO:0051560 | 3 | 0.106 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.100 | |
| adenine nucleotide transport | GO:0051503 | 2 | 0.096 | |
| purine nucleotide biosynthetic process | GO:0006164 | 83 | 0.092 | |
| heme biosynthetic process | GO:0006783 | 4 | 0.092 | |
| regulation of atp biosynthetic process | GO:2001169 | 2 | 0.091 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.090 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.088 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.086 | |
| catabolic process | GO:0009056 | 351 | 0.085 | |
| anion transport | GO:0006820 | 178 | 0.085 | |
| apoptotic mitochondrial changes | GO:0008637 | 10 | 0.084 | |
| cellular homeostasis | GO:0019725 | 252 | 0.080 | |
| programmed cell death | GO:0012501 | 392 | 0.075 | |
| purine ribonucleoside biosynthetic process | GO:0046129 | 21 | 0.074 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.074 | |
| nucleoside transport | GO:0015858 | 8 | 0.073 | |
| purine nucleoside monophosphate biosynthetic process | GO:0009127 | 20 | 0.068 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.068 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.063 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.062 | |
| intracellular transport | GO:0046907 | 185 | 0.062 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.062 | |
| nucleoside monophosphate biosynthetic process | GO:0009124 | 28 | 0.061 | |
| cofactor transport | GO:0051181 | 5 | 0.060 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 1 | 0.059 | |
| single organism catabolic process | GO:0044712 | 283 | 0.057 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.056 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.055 | |
| aerobic respiration | GO:0009060 | 13 | 0.055 | |
| ribonucleotide biosynthetic process | GO:0009260 | 85 | 0.054 | |
| cellular metal ion homeostasis | GO:0006875 | 172 | 0.052 | |
| dicarboxylic acid metabolic process | GO:0043648 | 42 | 0.052 | |
| ion homeostasis | GO:0050801 | 212 | 0.051 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.051 | |
| cation transport | GO:0006812 | 382 | 0.051 | |
| homeostatic process | GO:0042592 | 331 | 0.050 | |
| reactive oxygen species metabolic process | GO:0072593 | 37 | 0.050 | |
| purine containing compound biosynthetic process | GO:0072522 | 85 | 0.049 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 5 | 0.047 | |
| purine ribonucleoside monophosphate biosynthetic process | GO:0009168 | 20 | 0.046 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.046 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.046 | |
| cellular component assembly | GO:0022607 | 360 | 0.045 | |
| l glutamate transport | GO:0015813 | 7 | 0.045 | |
| nucleotide biosynthetic process | GO:0009165 | 98 | 0.045 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.043 | |
| cellular ion homeostasis | GO:0006873 | 184 | 0.043 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.041 | |
| adp transport | GO:0015866 | 1 | 0.041 | |
| generation of precursor metabolites and energy | GO:0006091 | 62 | 0.040 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.038 | |
| cellular calcium ion homeostasis | GO:0006874 | 160 | 0.038 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.036 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.036 | |
| amino acid import | GO:0043090 | 7 | 0.036 | |
| growth | GO:0040007 | 165 | 0.035 | |
| positive regulation of nucleotide biosynthetic process | GO:0030810 | 36 | 0.035 | |
| adult locomotory behavior | GO:0008344 | 4 | 0.034 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.034 | |
| reproduction | GO:0000003 | 245 | 0.034 | |
| positive regulation of transport | GO:0051050 | 245 | 0.033 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.033 | |
| cation homeostasis | GO:0055080 | 195 | 0.031 | |
| ribonucleoside biosynthetic process | GO:0042455 | 25 | 0.030 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.030 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.030 | |
| divalent inorganic cation transport | GO:0072511 | 134 | 0.030 | |
| negative regulation of hydrogen peroxide metabolic process | GO:0010727 | 2 | 0.029 | |
| response to oxidative stress | GO:0006979 | 186 | 0.029 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 167 | 0.029 | |
| regulation of hydrogen peroxide biosynthetic process | GO:0010728 | 2 | 0.029 | |
| dicarboxylic acid transport | GO:0006835 | 34 | 0.029 | |
| amino acid transport | GO:0006865 | 70 | 0.028 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.028 | |
| ribose phosphate biosynthetic process | GO:0046390 | 87 | 0.028 | |
| carboxylic acid transport | GO:0046942 | 115 | 0.028 | |
| regulation of ion transport | GO:0043269 | 245 | 0.028 | |
| response to nutrient | GO:0007584 | 248 | 0.028 | |
| regulation of molecular function | GO:0065009 | 398 | 0.027 | |
| divalent inorganic cation homeostasis | GO:0072507 | 165 | 0.027 | |
| thioester metabolic process | GO:0035383 | 28 | 0.027 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.026 | |
| sexual reproduction | GO:0019953 | 148 | 0.026 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.025 | |
| sulfur compound metabolic process | GO:0006790 | 70 | 0.025 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.025 | |
| l glutamate import | GO:0051938 | 2 | 0.024 | |
| monovalent inorganic cation transport | GO:0015672 | 172 | 0.024 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.024 | |
| inorganic cation transmembrane transport | GO:0098662 | 202 | 0.024 | |
| chemical homeostasis | GO:0048878 | 292 | 0.024 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 162 | 0.023 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.023 | |
| developmental growth | GO:0048589 | 100 | 0.023 | |
| cellular cation homeostasis | GO:0030003 | 180 | 0.023 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.023 | |
| purine nucleotide transport | GO:0015865 | 3 | 0.023 | |
| cellular catabolic process | GO:0044248 | 295 | 0.022 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.022 | |
| pigment metabolic process | GO:0042440 | 7 | 0.022 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.022 | |
| response to interleukin 1 | GO:0070555 | 55 | 0.021 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.021 | |
| regulation of transporter activity | GO:0032409 | 50 | 0.021 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.021 | |
| glycosyl compound biosynthetic process | GO:1901659 | 25 | 0.021 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.021 | |
| anion transmembrane transport | GO:0098656 | 77 | 0.021 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.021 | |
| single organism reproductive process | GO:0044702 | 297 | 0.020 | |
| regulation of protein complex assembly | GO:0043254 | 33 | 0.020 | |
| anatomical structure homeostasis | GO:0060249 | 29 | 0.020 | |
| cellular response to organic cyclic compound | GO:0071407 | 202 | 0.020 | |
| hydrogen peroxide metabolic process | GO:0042743 | 13 | 0.020 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 81 | 0.019 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.019 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.019 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.019 | |
| response to nutrient levels | GO:0031667 | 370 | 0.018 | |
| l amino acid transport | GO:0015807 | 21 | 0.018 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.018 | |
| aging | GO:0007568 | 241 | 0.018 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 140 | 0.018 | |
| sulfur compound biosynthetic process | GO:0044272 | 19 | 0.018 | |
| apoptotic signaling pathway | GO:0097190 | 27 | 0.018 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.017 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.017 | |
| apoptotic process | GO:0006915 | 381 | 0.017 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.017 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.017 | |
| monocarboxylic acid metabolic process | GO:0032787 | 152 | 0.017 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.017 | |
| regulation of kinase activity | GO:0043549 | 117 | 0.016 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.016 | |
| isotype switching | GO:0045190 | 1 | 0.016 | |
| oligopeptide transport | GO:0006857 | 4 | 0.016 | |
| mitochondrial transport | GO:0006839 | 19 | 0.016 | |
| gamete generation | GO:0007276 | 124 | 0.016 | |
| interleukin 12 production | GO:0032615 | 3 | 0.016 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.016 | |
| somatic recombination of immunoglobulin genes involved in immune response | GO:0002204 | 1 | 0.016 | |
| oxaloacetate metabolic process | GO:0006107 | 6 | 0.016 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.015 | |
| metanephric tubule development | GO:0072170 | 4 | 0.015 | |
| response to peptide hormone | GO:0043434 | 278 | 0.015 | |
| l amino acid import | GO:0043092 | 5 | 0.015 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 119 | 0.015 | |
| spermatogenesis | GO:0007283 | 99 | 0.015 | |
| establishment of vesicle localization | GO:0051650 | 31 | 0.015 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.015 | |
| central nervous system development | GO:0007417 | 311 | 0.015 | |
| fatty acid metabolic process | GO:0006631 | 99 | 0.014 | |
| inorganic ion transmembrane transport | GO:0098660 | 229 | 0.014 | |
| oxidoreduction coenzyme metabolic process | GO:0006733 | 31 | 0.014 | |
| reproductive process | GO:0022414 | 372 | 0.014 | |
| regulation of nucleotide biosynthetic process | GO:0030808 | 47 | 0.013 | |
| male gamete generation | GO:0048232 | 99 | 0.013 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.013 | |
| endomembrane system organization | GO:0010256 | 48 | 0.013 | |
| positive regulation of ion transport | GO:0043270 | 94 | 0.013 | |
| response to mechanical stimulus | GO:0009612 | 134 | 0.013 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.013 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 13 | 0.013 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.012 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.012 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.012 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 4 | 0.012 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.012 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.012 | |
| purine nucleobase metabolic process | GO:0006144 | 4 | 0.012 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.012 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.012 | |
| membrane organization | GO:0061024 | 94 | 0.012 | |
| axonogenesis | GO:0007409 | 71 | 0.011 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.011 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.011 | |
| nucleoside phosphate catabolic process | GO:1901292 | 140 | 0.011 | |
| response to toxic substance | GO:0009636 | 133 | 0.011 | |
| head development | GO:0060322 | 247 | 0.011 | |
| amine metabolic process | GO:0009308 | 38 | 0.011 | |
| nucleoside biosynthetic process | GO:0009163 | 25 | 0.011 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.011 | |
| purine ribonucleotide transport | GO:0015868 | 3 | 0.011 | |
| action potential | GO:0001508 | 54 | 0.011 | |
| organic anion transport | GO:0015711 | 132 | 0.011 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.011 | |
| purine nucleoside catabolic process | GO:0006152 | 124 | 0.010 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.010 | |
| response to tumor cell | GO:0002347 | 4 | 0.010 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.010 | |
| acetyl coa biosynthetic process | GO:0006085 | 6 | 0.010 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.010 | |
| ribonucleotide catabolic process | GO:0009261 | 136 | 0.010 | |
| protein complex assembly | GO:0006461 | 263 | 0.010 | |
| lipid storage | GO:0019915 | 1 | 0.010 | |
| small molecule biosynthetic process | GO:0044283 | 124 | 0.010 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.010 | |
| regulation of protein maturation | GO:1903317 | 50 | 0.010 | |
| circulatory system development | GO:0072359 | 134 | 0.010 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.010 | |
| negative regulation of protein modification by small protein conjugation or removal | GO:1903321 | 4 | 0.010 | |
| maintenance of location | GO:0051235 | 17 | 0.010 | |
| positive regulation of transmembrane transport | GO:0034764 | 25 | 0.010 | |