Rattus norvegicus

107 known processes

C3

complement component 3

C3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
complement activationGO:0006956110.944
response to campGO:0051591910.666
immune effector processGO:0002252530.616
response to molecule of bacterial originGO:00022371940.596
response to bacteriumGO:00096172000.590
response to nutrient levelsGO:00316673700.558
immune responseGO:00069551040.509
response to other organismGO:00517072200.493
response to purine containing compoundGO:00140741260.459
response to external biotic stimulusGO:00432072210.401
regulation of immune system processGO:00026821230.361
response to biotic stimulusGO:00096072260.333
response to inorganic substanceGO:00100353770.329
response to nutrientGO:00075842480.325
regulation of multicellular organismal developmentGO:20000263760.307
activation of immune responseGO:0002253260.295
response to lipopolysaccharideGO:00324961910.288
positive regulation of response to stimulusGO:00485842850.278
response to extracellular stimulusGO:00099913800.267
regulation of catalytic activityGO:00507903040.264
regulation of cell proliferationGO:00421273590.239
regulation of cell differentiationGO:00455953200.233
b cell mediated immunityGO:001972440.219
positive regulation of developmental processGO:00510942830.218
regulation of anatomical structure sizeGO:00900661350.217
immune system processGO:00023762040.214
response to organophosphorusGO:00466831020.213
blood coagulationGO:0007596260.197
negative regulation of metabolic processGO:00098923310.193
metal ion transportGO:00300012890.187
protein activation cascadeGO:0072376120.184
protein phosphorylationGO:00064683450.184
regulation of protein metabolic processGO:00512462890.182
regulation of locomotionGO:00400121480.177
negative regulation of multicellular organismal processGO:00512412030.172
regulation of molecular functionGO:00650093980.172
positive regulation of neurogenesisGO:00507691650.167
organic acid metabolic processGO:00060822920.162
cellular response to lipidGO:00713962010.155
neurological system processGO:00508772190.153
agingGO:00075682410.150
acute phase responseGO:0006953200.146
cellular response to endogenous stimulusGO:00714953770.145
cell projection organizationGO:00300303020.145
regulation of immune responseGO:0050776550.137
response to metal ionGO:00100382530.133
positive regulation of immune system processGO:0002684900.133
response to woundingGO:00096112540.129
leukocyte mediated immunityGO:0002443280.129
cellular component assemblyGO:00226073600.128
localization of cellGO:00516742020.124
response to hypoxiaGO:00016662310.123
carboxylic acid metabolic processGO:00197522890.121
positive regulation of cellular component organizationGO:00511302000.120
regulation of protein modification processGO:00313991940.115
regulation of neurogenesisGO:00507672470.115
programmed cell deathGO:00125013920.112
single organism organelle organizationGO:19025891800.111
negative regulation of cellular metabolic processGO:00313242810.101
positive regulation of phosphorylationGO:00423271770.100
regulation of phosphorylationGO:00423252480.099
chemosensory behaviorGO:000763520.098
cellular response to oxygen containing compoundGO:19017013860.095
positive regulation of cell differentiationGO:00455972170.094
oxoacid metabolic processGO:00434362900.094
cation transportGO:00068123820.090
humoral immune responseGO:0006959120.090
neuron projection developmentGO:00311752730.088
coagulationGO:0050817280.088
regulation of system processGO:00440572080.087
cellular response to hormone stimulusGO:00328702470.086
response to acid chemicalGO:00011012220.085
homeostatic processGO:00425923310.084
cellular amine metabolic processGO:0044106380.084
cellular amino acid metabolic processGO:00065201070.083
positive regulation of nervous system developmentGO:00519621780.083
regulation of cellular component organizationGO:00511283680.081
wound healingGO:00420601220.080
multicellular organismal homeostasisGO:0048871490.080
cell junction organizationGO:0034330210.080
cell morphogenesis involved in differentiationGO:00009041190.080
cellular response to nitrogen compoundGO:19016992100.079
regulation of cell developmentGO:00602842630.078
cell part morphogenesisGO:00329901230.078
carboxylic acid biosynthetic processGO:0046394830.077
cell projection morphogenesisGO:00488581230.076
cellular response to organonitrogen compoundGO:00714171970.076
inflammatory responseGO:00069541500.076
positive regulation of protein phosphorylationGO:00019341350.074
gliogenesisGO:0042063930.074
peptidyl tyrosine phosphorylationGO:0018108720.073
neuron projection morphogenesisGO:00488121220.070
regulation of cell projection organizationGO:00313441750.069
signal transduction by phosphorylationGO:00230141440.069
response to decreased oxygen levelsGO:00362932370.069
regulation of programmed cell deathGO:00430673410.068
immunoglobulin mediated immune responseGO:001606440.068
peptidyl amino acid modificationGO:00181931260.068
regulation of apoptotic processGO:00429813350.067
amine metabolic processGO:0009308380.067
multicellular organismal signalingGO:0035637440.066
regulation of cellular localizationGO:00603412630.066
glial cell differentiationGO:0010001650.066
response to peptide hormoneGO:00434342780.065
positive regulation of phosphorus metabolic processGO:00105622620.064
regulation of cell activationGO:0050865500.064
behaviorGO:00076102050.063
cellular component morphogenesisGO:00329891550.062
positive regulation of cell developmentGO:00107201760.061
response to lead ionGO:0010288330.060
response to glucocorticoidGO:00513842230.059
monocarboxylic acid metabolic processGO:00327871520.058
cytoskeleton organizationGO:00070101110.057
regulation of cell migrationGO:00303341280.057
intracellular signal transductionGO:00355563140.057
negative regulation of developmental processGO:00510931250.056
cellular component movementGO:00069282480.055
single organism behaviorGO:00447081300.055
negative regulation of macromolecule metabolic processGO:00106052600.055
regulation of acute inflammatory responseGO:0002673230.054
rna biosynthetic processGO:00327743800.054
regulation of neural precursor cell proliferationGO:2000177160.053
cellular response to peptide hormone stimulusGO:00713751200.053
regulation of cellular amine metabolic processGO:003323880.051
gland developmentGO:00487321550.050
blood circulationGO:00080151830.050
cellular ketone metabolic processGO:0042180510.050
response to tumor necrosis factorGO:0034612560.049
action potentialGO:0001508540.049
positive regulation of blood coagulationGO:003019440.049
cellular response to organic cyclic compoundGO:00714072020.049
positive regulation of cell proliferationGO:00082842490.049
defense responseGO:00069521940.048
response to corticosteroidGO:00319602350.048
regulation of phosphate metabolic processGO:00192203490.048
axon developmentGO:0061564960.047
positive regulation of multicellular organismal processGO:00512403870.045
proteolysisGO:00065081750.045
neuron developmentGO:00486662860.045
regulation of nervous system developmentGO:00519602640.045
cell cell signalingGO:00072673350.044
neuron deathGO:00709971270.043
regulation of cellular protein metabolic processGO:00322682670.043
catabolic processGO:00090563510.042
cellular lipid metabolic processGO:00442552080.042
positive regulation of phosphate metabolic processGO:00459372620.041
macromolecular complex subunit organizationGO:00439333390.041
macromolecule localizationGO:00330362520.041
cell type specific apoptotic processGO:00972851340.041
regulation of phosphorus metabolic processGO:00511743490.041
regulation of intracellular signal transductionGO:19025312180.040
erk1 and erk2 cascadeGO:0070371480.040
single organism biosynthetic processGO:00447113420.040
organic substance catabolic processGO:19015753160.040
regulation of neuron differentiationGO:00456642080.040
regulation of cellular ketone metabolic processGO:0010565270.039
respiratory system developmentGO:0060541450.039
regulation of neuron deathGO:19012141150.038
regenerationGO:00310991630.038
positive regulation of catalytic activityGO:00430851840.038
positive regulation of cell communicationGO:00106472710.038
positive regulation of transportGO:00510502450.038
positive regulation of cellular amino acid metabolic processGO:004576410.037
cellular component biogenesisGO:00440853680.037
nucleic acid templated transcriptionGO:00976593790.036
positive regulation of cellular protein metabolic processGO:00322701670.036
reactive nitrogen species metabolic processGO:200105710.036
positive regulation of signalingGO:00230562700.036
tube developmentGO:0035295890.036
positive regulation of cellular amine metabolic processGO:003324030.036
regulation of cellular amino acid metabolic processGO:000652120.036
cellular homeostasisGO:00197252520.035
regulation of nucleic acid templated transcriptionGO:19035063800.035
negative regulation of response to stimulusGO:00485851550.035
regulation of blood circulationGO:19035221100.034
regulation of ion transportGO:00432692450.033
cellular response to stressGO:00335542690.032
regulation of rna metabolic processGO:00512523910.032
mapk cascadeGO:00001651400.032
carbohydrate derivative metabolic processGO:19011353460.032
negative regulation of nervous system developmentGO:0051961790.031
cell migrationGO:00164771970.031
response to monosaccharideGO:00342841590.031
cell motilityGO:00488702020.030
lipid metabolic processGO:00066292830.030
reproductive processGO:00224143720.030
regulation of neurological system processGO:0031644430.029
regulation of peptide secretionGO:0002791820.029
tissue developmentGO:00098882520.029
neuron differentiationGO:00301823680.029
negative regulation of humoral immune responseGO:000292140.029
regulation of axonogenesisGO:0050770370.029
response to transition metal nanoparticleGO:19902671220.029
central nervous system developmentGO:00074173110.029
regulation of hormone levelsGO:00108171870.029
response to cytokineGO:00340972150.028
positive regulation of protein modification processGO:00314011420.028
digestive system developmentGO:0055123410.028
astrocyte developmentGO:001400240.028
cellular response to cytokine stimulusGO:00713451270.028
innate immune responseGO:0045087350.028
positive regulation of signal transductionGO:00099671750.028
negative regulation of neuron apoptotic processGO:0043524450.028
positive regulation of immune responseGO:0050778420.028
response to estradiolGO:00323551640.028
aromatic compound catabolic processGO:00194391680.028
positive regulation of neuron projection developmentGO:0010976990.027
neuronal action potentialGO:0019228350.027
regulation of transcription dna templatedGO:00063553740.027
response to oxygen levelsGO:00704822650.027
cell morphogenesis involved in neuron differentiationGO:00486671060.027
hormone secretionGO:00468791150.027
positive regulation of neuron differentiationGO:00456661260.027
regulation of catabolic processGO:00098941130.026
actin filament based processGO:0030029860.026
regulation of defense responseGO:0031347680.026
icosanoid metabolic processGO:0006690380.026
positive regulation of protein metabolic processGO:00512471780.026
anterior posterior pattern specificationGO:000995210.026
regulation of neuron projection developmentGO:00109751610.025
regulation of kinase activityGO:00435491170.025
negative regulation of phosphorus metabolic processGO:0010563800.025
reactive oxygen species metabolic processGO:0072593370.025
cellular chemical homeostasisGO:00550822470.025
negative regulation of phosphate metabolic processGO:0045936800.025
multi organism reproductive processGO:00447032620.025
stress activated protein kinase signaling cascadeGO:0031098370.025
negative regulation of innate immune responseGO:004582440.024
organonitrogen compound catabolic processGO:19015651790.024
organophosphate catabolic processGO:00464341480.024
regulation of tube sizeGO:0035150890.024
biological adhesionGO:00226101100.024
transmission of nerve impulseGO:0019226420.024
tissue homeostasisGO:0001894280.024
locomotionGO:00400112370.024
glycosyl compound catabolic processGO:19016581260.024
negative regulation of signalingGO:00230571570.023
axis specificationGO:000979840.023
organelle organizationGO:00069962660.023
positive regulation of reactive oxygen species biosynthetic processGO:190342820.023
cellular response to follicle stimulating hormone stimulusGO:0071372130.023
negative regulation of immune responseGO:0050777150.023
response to retinoic acidGO:0032526630.023
positive regulation of locomotionGO:00400171020.023
positive regulation of response to woundingGO:1903036340.023
regulation of neuron apoptotic processGO:0043523830.023
regulation of body fluid levelsGO:0050878900.022
negative regulation of gene expressionGO:00106291990.022
negative regulation of cellular protein metabolic processGO:00322691060.022
positive regulation of neural precursor cell proliferationGO:2000179100.022
intracellular transportGO:00469071850.022
response to fatty acidGO:0070542650.022
cellular response to molecule of bacterial originGO:0071219560.022
cellular response to campGO:0071320260.022
mesoderm developmentGO:000749820.022
single organismal cell cell adhesionGO:0016337420.022
negative regulation of molecular functionGO:00440921330.022
organic hydroxy compound metabolic processGO:19016151150.022
negative regulation of cell differentiationGO:0045596990.021
cation homeostasisGO:00550801950.021
positive regulation of hemostasisGO:190004840.021
positive regulation of molecular functionGO:00440932300.021
negative regulation of cell deathGO:00605482290.021
heterocycle catabolic processGO:00467001670.021
lymphocyte mediated immunityGO:0002449140.021
apoptotic processGO:00069153810.021
multicellular organismal reproductive processGO:00486092330.021
response to peptideGO:19016522920.021
regulation of leukocyte proliferationGO:0070663260.021
brain renin angiotensin systemGO:000203530.021
axonogenesisGO:0007409710.020
regulation of protein phosphorylationGO:00019321830.020
cellular response to biotic stimulusGO:0071216590.020
vesicle mediated transportGO:00161921810.020
peptidyl tyrosine modificationGO:0018212720.020
stress activated mapk cascadeGO:0051403350.020
peptide secretionGO:0002790860.020
negative regulation of cell communicationGO:00106481580.020
regulation of membrane potentialGO:00423911100.020
small molecule biosynthetic processGO:00442831240.020
secretionGO:00469033070.020
response to thyroid hormoneGO:0097066170.019
response to interleukin 1GO:0070555550.019
cell growthGO:00160491040.019
carbohydrate metabolic processGO:00059751300.019
negative regulation of transportGO:00510511360.019
positive regulation of hydrolase activityGO:0051345860.019
cognitionGO:0050890920.019
calcium ion homeostasisGO:00550741620.019
spindle organizationGO:000705120.019
anatomical structure morphogenesisGO:00096532980.019
chemical homeostasisGO:00488782920.019
g protein coupled receptor signaling pathwayGO:00071862420.019
regulation of secretionGO:00510462240.019
positive regulation of cell deathGO:00109421840.019
negative regulation of neuron differentiationGO:0045665620.019
regulation of reactive oxygen species metabolic processGO:2000377260.019
negative regulation of catalytic activityGO:00430861030.019
regulation of peptide transportGO:0090087870.018
positive regulation of blood circulationGO:1903524650.018
sensory perceptionGO:00076001010.018
cellular response to interleukin 1GO:0071347370.018
negative regulation of protein metabolic processGO:00512481140.018
cell morphogenesisGO:00009021420.018
response to gonadotropinGO:0034698340.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.018
mitotic spindle organizationGO:000705220.018
nitrogen compound transportGO:00717052290.018
nucleobase containing small molecule metabolic processGO:00550863160.018
single organism catabolic processGO:00447122830.018
vascular process in circulatory systemGO:0003018960.018
sexual reproductionGO:00199531480.018
response to ethanolGO:00454711620.018
regulation of peptidase activityGO:0052547550.018
protein transportGO:00150311320.017
multicellular organism reproductionGO:00325042330.017
ion homeostasisGO:00508012120.017
response to axon injuryGO:0048678590.017
response to hexoseGO:00097461440.017
regulation of calcium ion transportGO:0051924770.017
cellular cation homeostasisGO:00300031800.017
protein maturationGO:0051604680.017
organonitrogen compound biosynthetic processGO:19015661670.017
single organism reproductive processGO:00447022970.017
response to glucoseGO:00097491360.017
positive regulation of cell projection organizationGO:00313461110.017
regulation of signal transductionGO:00099663180.017
regulation of response to stressGO:00801341260.017
regulation of cellular component movementGO:00512701500.017
gamete generationGO:00072761240.017
single organism cell adhesionGO:0098602460.017
negative regulation of neuron deathGO:1901215690.017
cellular response to acid chemicalGO:0071229750.017
regulation of immune effector processGO:0002697320.016
positive regulation of intracellular signal transductionGO:19025331380.016
positive regulation of nitrogen compound metabolic processGO:00511733340.016
smooth muscle contractionGO:0006939370.016
antigen processing and presentationGO:001988220.016
regulation of transferase activityGO:00513381230.016
cell cell junction organizationGO:0045216200.016
cell junction assemblyGO:0034329180.016
rna metabolic processGO:00160704060.016
positive regulation of programmed cell deathGO:00430681570.016
vasoconstrictionGO:0042310540.016
lipid localizationGO:0010876620.016
cellular response to nutrient levelsGO:0031669600.016
regulation of response to external stimulusGO:00321011060.016
protein importGO:0017038370.016
lipid transportGO:0006869610.016
protein complex biogenesisGO:00702712630.016
single organism intracellular transportGO:19025821660.015
transcription dna templatedGO:00063513770.015
positive regulation of secretionGO:00510471400.015
macromolecular complex assemblyGO:00650032730.015
amide transportGO:00428861050.015
rho protein signal transductionGO:0007266110.015
response to alkaloidGO:00432791320.015
regulation of organelle organizationGO:0033043800.015
anatomical structure homeostasisGO:0060249290.015
signal releaseGO:00230611450.015
protein complex subunit organizationGO:00718223020.015
regulation of blood vessel sizeGO:0050880890.015
protein localizationGO:00081041910.015
organophosphate metabolic processGO:00196373700.015
single organism carbohydrate metabolic processGO:00447231180.015
metal ion homeostasisGO:00550651860.015
leukocyte differentiationGO:0002521300.015
muscle system processGO:00030121150.015
response to vitaminGO:00332731310.015
regulation of response to woundingGO:1903034690.014
positive regulation of cell activationGO:0050867340.014
negative regulation of apoptotic processGO:00430661810.014
acute inflammatory responseGO:0002526580.014
response to amino acidGO:0043200750.014
cellular response to corticosteroid stimulusGO:0071384690.014
reproductive structure developmentGO:00486081280.014
embryonic pattern specificationGO:000988010.014
cellular nitrogen compound catabolic processGO:00442701630.014
response to growth hormoneGO:0060416210.014
establishment of protein localizationGO:00451841410.014
regulation of reactive oxygen species biosynthetic processGO:190342650.014
regulation of cell motilityGO:20001451310.014
endocytosisGO:0006897840.014
positive regulation of cell motilityGO:2000147970.014
organic cyclic compound catabolic processGO:19013611750.014
positive regulation of reactive oxygen species metabolic processGO:2000379160.014
liver developmentGO:0001889900.013
cellular catabolic processGO:00442482950.013
regulation of cell morphogenesis involved in differentiationGO:0010769720.013
positive regulation of kinase activityGO:0033674770.013
negative regulation of cell proliferationGO:00082851190.013
regulation of peptide hormone secretionGO:0090276800.013
ensheathment of neuronsGO:0007272400.013
regulation of establishment of protein localizationGO:0070201690.013
negative regulation of biosynthetic processGO:00098901680.013
platelet aggregationGO:007052740.013
regulation of amine transportGO:0051952540.013
cellular metal ion homeostasisGO:00068751720.013
antigen processing and presentation of peptide antigenGO:004800220.013
reactive oxygen species biosynthetic processGO:190340980.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
sequestering of metal ionGO:005123890.013
negative regulation of cellular component organizationGO:0051129830.013
peptide transportGO:0015833970.013
olfactory learningGO:000835510.013
sequestering of calcium ionGO:005120880.013
negative regulation of peptidase activityGO:0010466380.013
regulation of muscle system processGO:0090257790.013
regulation of muscle contractionGO:0006937530.012
regulation of hormone secretionGO:00468831060.012
regulation of cell morphogenesisGO:0022604770.012
hepaticobiliary system developmentGO:0061008900.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of hydrolase activityGO:00513361430.012
regulation of proteolysisGO:0030162660.012
angiotensin mediated drinking behaviorGO:000305120.012
gtp catabolic processGO:0006184710.012
defense response to gram negative bacteriumGO:005082930.012
calcium ion transportGO:00068161310.012
hormone transportGO:00099141210.012
regulation of mapk cascadeGO:00434081160.012
positive regulation of gene expressionGO:00106282440.012
regulation of endocytosisGO:0030100420.012
negative regulation of endopeptidase activityGO:0010951360.012
response to mineralocorticoidGO:0051385490.012
regulation of cell growthGO:0001558850.012
developmental process involved in reproductionGO:00030061590.012
leukocyte activation involved in immune responseGO:0002366160.012
regulation of cellular component sizeGO:0032535510.012
sex differentiationGO:00075481130.012
circulatory system processGO:00030131830.012
negative regulation of cell developmentGO:0010721820.012
cellular response to growth factor stimulusGO:00713631620.012
regulation of secretion by cellGO:19035302080.012
nucleoside triphosphate metabolic processGO:00091411440.011
gastrulationGO:000736920.011
regulation of vasoconstrictionGO:0019229440.011
olfactory behaviorGO:004204820.011
cellular response to external stimulusGO:00714961180.011
cytosolic calcium ion homeostasisGO:00514801400.011
actin filament bundle assemblyGO:0051017190.011
protein oligomerizationGO:00512591910.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
nucleobase containing compound catabolic processGO:00346551520.011
response to phGO:0009268270.011
regulation of b cell differentiationGO:004557710.011
blood coagulation fibrin clot formationGO:007237810.011
cellular ion homeostasisGO:00068731840.011
organic anion transportGO:00157111320.011
nucleoside phosphate metabolic processGO:00067532830.011
maintenance of locationGO:0051235170.011
regulation of protein maturationGO:1903317500.011
positive regulation of protein kinase activityGO:0045860730.011
regulation of cellular response to stressGO:0080135490.011
ras protein signal transductionGO:0007265290.011
regulation of map kinase activityGO:0043405530.011
negative regulation of cellular amine metabolic processGO:003323930.011
regulation of anatomical structure morphogenesisGO:00226031410.011
embryonic axis specificationGO:000057810.011
purine containing compound metabolic processGO:00725212530.011
response to growth factorGO:00708481890.011
small gtpase mediated signal transductionGO:0007264360.011
negative regulation of signal transductionGO:0009968830.011
protein processingGO:0016485680.011
cellular response to inorganic substanceGO:0071241650.011
positive regulation of cell migrationGO:0030335960.011
regulation of smooth muscle cell proliferationGO:0048660750.011
regulation of intracellular transportGO:0032386650.010
positive regulation of transferase activityGO:0051347810.010
growthGO:00400071650.010
cellular macromolecule localizationGO:00707271220.010
purine nucleotide metabolic processGO:00061632290.010
positive regulation of cellular component movementGO:00512721020.010
negative regulation of immune system processGO:0002683390.010
single organism cellular localizationGO:19025801020.010
myelinationGO:0042552390.010
learning or memoryGO:0007611900.010
regulation of ion homeostasisGO:2000021630.010
negative regulation of protein phosphorylationGO:0001933440.010
actin filament organizationGO:0007015420.010
head developmentGO:00603222470.010
cellular response to extracellular stimulusGO:0031668730.010
synaptic growth at neuromuscular junctionGO:005112410.010
response to reactive oxygen speciesGO:00003021200.010

C3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.125
inherited metabolic disorderDOID:65500.030
gastrointestinal system diseaseDOID:7700.028
disease of anatomical entityDOID:700.028
vascular diseaseDOID:17800.024
cardiovascular system diseaseDOID:128700.024
integumentary system diseaseDOID:1600.018
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
acquired metabolic diseaseDOID:006015800.012
artery diseaseDOID:005082800.011