Rattus norvegicus

3 known processes

C8b

complement component 8, beta polypeptide

C8b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular homeostasisGO:00197252520.550
response to acid chemicalGO:00011012220.382
cellular response to oxygen containing compoundGO:19017013860.364
response to muscle activity involved in regulation of muscle adaptationGO:001487320.347
gland developmentGO:00487321550.335
cellular chemical homeostasisGO:00550822470.305
cellular response to hormone stimulusGO:00328702470.263
agingGO:00075682410.259
response to estrogenGO:00436272320.251
cellular response to corticosteroid stimulusGO:0071384690.251
response to woundingGO:00096112540.250
Rat
response to extracellular stimulusGO:00099913800.239
response to glucocorticoidGO:00513842230.232
response to ketoneGO:19016541820.221
response to peptide hormoneGO:00434342780.219
response to nutrient levelsGO:00316673700.202
extracellular matrix constituent secretionGO:007027840.198
liver developmentGO:0001889900.197
cellular response to lipidGO:00713962010.194
cellular response to steroid hormone stimulusGO:0071383930.189
regulation of multicellular organismal developmentGO:20000263760.188
response to peptideGO:19016522920.178
wound healingGO:00420601220.178
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.177
protein complex subunit organizationGO:00718223020.176
female pregnancyGO:00075651220.175
cellular response to endogenous stimulusGO:00714953770.172
regulation of cell proliferationGO:00421273590.168
response to estradiolGO:00323551640.168
regulation of anatomical structure sizeGO:00900661350.168
chemical homeostasisGO:00488782920.165
regulation of anatomical structure morphogenesisGO:00226031410.163
anatomical structure morphogenesisGO:00096532980.163
regulation of tube sizeGO:0035150890.152
positive regulation of multicellular organismal processGO:00512403870.150
regulation of serine type peptidase activityGO:190257110.148
response to inorganic substanceGO:00100353770.147
regulation of cellular localizationGO:00603412630.143
developmental growthGO:00485891000.135
cellular response to organic cyclic compoundGO:00714072020.134
regulation of locomotionGO:00400121480.132
cellular response to glucocorticoid stimulusGO:0071385680.129
regulation of body fluid levelsGO:0050878900.129
Rat
ion homeostasisGO:00508012120.127
cell cell signalingGO:00072673350.125
regulation of secretionGO:00510462240.120
response to glucoseGO:00097491360.120
positive regulation of extracellular matrix organizationGO:190305540.118
reproductive processGO:00224143720.117
regulation of cell migrationGO:00303341280.117
negative regulation of multicellular organismal processGO:00512412030.112
macromolecular complex assemblyGO:00650032730.110
response to nutrientGO:00075842480.108
response to corticosteroidGO:00319602350.107
intracellular signal transductionGO:00355563140.104
mapk cascadeGO:00001651400.104
regulation of cell differentiationGO:00455953200.101
regulation of neurogenesisGO:00507672470.101
multi organism reproductive processGO:00447032620.100
cellular metal ion homeostasisGO:00068751720.100
positive regulation of developmental processGO:00510942830.097
cellular component movementGO:00069282480.097
defense responseGO:00069521940.096
positive regulation of response to stimulusGO:00485842850.095
single organism behaviorGO:00447081300.092
regulation of protein metabolic processGO:00512462890.091
cellular component assemblyGO:00226073600.089
central nervous system developmentGO:00074173110.087
response to cytokineGO:00340972150.087
growthGO:00400071650.087
reactive oxygen species metabolic processGO:0072593370.086
tissue developmentGO:00098882520.085
regulation of molecular functionGO:00650093980.085
protein complex biogenesisGO:00702712630.084
blood circulationGO:00080151830.084
negative regulation of cell proliferationGO:00082851190.082
excretionGO:0007588240.082
angiotensin mediated drinking behaviorGO:000305120.081
blood coagulationGO:0007596260.081
Rat
cell motilityGO:00488702020.080
positive regulation of cell communicationGO:00106472710.080
cellular lipid metabolic processGO:00442552080.079
secretionGO:00469033070.079
locomotionGO:00400112370.074
cellular response to nitrogen compoundGO:19016992100.074
positive regulation of extracellular matrix constituent secretionGO:000333120.073
regulation of blood vessel sizeGO:0050880890.073
response to campGO:0051591910.072
inflammatory responseGO:00069541500.072
nitrogen compound transportGO:00717052290.072
signal transduction by phosphorylationGO:00230141440.070
response to purine containing compoundGO:00140741260.070
macromolecule localizationGO:00330362520.069
cellular response to stressGO:00335542690.069
negative regulation of response to stimulusGO:00485851550.068
cell projection organizationGO:00300303020.067
regulation of secretion by cellGO:19035302080.066
head developmentGO:00603222470.066
coagulationGO:0050817280.066
Rat
positive regulation of neurogenesisGO:00507691650.065
response to hexoseGO:00097461440.063
multicellular organismal signalingGO:0035637440.063
rhythmic processGO:00485111560.063
response to metal ionGO:00100382530.063
cellular response to external stimulusGO:00714961180.062
oxoacid metabolic processGO:00434362900.061
organ morphogenesisGO:0009887750.061
regulation of epithelial cell proliferationGO:0050678490.061
single organism reproductive processGO:00447022970.060
renin angiotensin regulation of aldosterone productionGO:000201830.060
carboxylic acid metabolic processGO:00197522890.060
reproductionGO:00000032450.060
apoptotic processGO:00069153810.060
Rat
ovulation cycleGO:0042698670.059
cellular response to alcoholGO:0097306870.058
regenerationGO:00310991630.058
organic acid metabolic processGO:00060822920.057
regulation of apoptotic processGO:00429813350.057
Rat
circulatory system developmentGO:00723591340.057
cellular ion homeostasisGO:00068731840.056
positive regulation of locomotionGO:00400171020.056
cation homeostasisGO:00550801950.055
single organism biosynthetic processGO:00447113420.055
cellular response to ketoneGO:1901655510.054
vasoconstrictionGO:0042310540.054
response to monosaccharideGO:00342841590.054
negative regulation of gene expressionGO:00106291990.054
response to other organismGO:00517072200.054
renal sodium excretionGO:0035812200.054
regulation of cellular component movementGO:00512701500.053
protein complex assemblyGO:00064612630.053
behaviorGO:00076102050.053
negative regulation of signal transductionGO:0009968830.053
regulation of extracellular matrix constituent secretionGO:000333020.052
positive regulation of cell proliferationGO:00082842490.052
negative regulation of macromolecule metabolic processGO:00106052600.052
regulation of response to external stimulusGO:00321011060.051
reactive nitrogen species metabolic processGO:200105710.051
localization of cellGO:00516742020.050
regulation of catalytic activityGO:00507903040.050
neuron differentiationGO:00301823680.050
response to alkaloidGO:00432791320.049
regulation of rna biosynthetic processGO:20011413810.049
response to corticosteroneGO:0051412400.049
negative regulation of developmental processGO:00510931250.049
anatomical structure formation involved in morphogenesisGO:0048646830.048
positive regulation of cellular biosynthetic processGO:00313282950.048
muscle cell proliferationGO:0033002840.048
tonic smooth muscle contractionGO:001482040.048
regulation of growthGO:00400081050.047
negative regulation of metabolic processGO:00098923310.046
acute inflammatory responseGO:0002526580.046
brain renin angiotensin systemGO:000203530.046
negative regulation of cell communicationGO:00106481580.046
circulatory system processGO:00030131830.045
regulation of phosphorus metabolic processGO:00511743490.045
urogenital system developmentGO:0001655780.044
reproductive structure developmentGO:00486081280.044
positive regulation of cell developmentGO:00107201760.044
circadian rhythmGO:0007623880.044
fibrinolysisGO:004273020.044
developmental process involved in reproductionGO:00030061590.044
cellular component biogenesisGO:00440853680.043
forebrain developmentGO:0030900980.043
transmission of nerve impulseGO:0019226420.043
muscle structure developmentGO:0061061870.042
response to organophosphorusGO:00466831020.042
transcription from rna polymerase ii promoterGO:00063662520.042
regulation of peptide hormone secretionGO:0090276800.042
regulation of neuron differentiationGO:00456642080.042
response to vitaminGO:00332731310.042
regulation of system processGO:00440572080.041
positive regulation of nervous system developmentGO:00519621780.041
gonad developmentGO:00084061040.040
regulation of intracellular signal transductionGO:19025312180.040
positive regulation of phosphorus metabolic processGO:00105622620.040
divalent metal ion transportGO:00708381320.040
regulation of nervous system developmentGO:00519602640.039
lipid biosynthetic processGO:00086101280.039
regulation of reactive oxygen species biosynthetic processGO:190342650.039
carboxylic acid biosynthetic processGO:0046394830.039
kidney developmentGO:0001822670.039
regulation of cell motilityGO:20001451310.039
regulation of blood circulationGO:19035221100.039
regulation of fibrinolysisGO:005191720.039
multi multicellular organism processGO:00447061380.039
innate immune responseGO:0045087350.039
macromolecular complex subunit organizationGO:00439333390.039
regulation of hormone levelsGO:00108171870.038
positive regulation of biosynthetic processGO:00098913190.038
immune system processGO:00023762040.038
tissue remodelingGO:0048771400.038
artery smooth muscle contractionGO:001482440.038
regulation of synaptic transmissionGO:00508041410.038
response to bacteriumGO:00096172000.038
positive regulation of cellular component organizationGO:00511302000.038
regulation of response to stressGO:00801341260.038
regulation of cellular protein metabolic processGO:00322682670.037
telencephalon developmentGO:0021537620.037
positive regulation of cell migrationGO:0030335960.037
positive regulation of cellular component movementGO:00512721020.036
renal system processGO:0003014400.036
regulation of cell growthGO:0001558850.036
positive regulation of protein metabolic processGO:00512471780.036
negative regulation of protein maturationGO:1903318470.036
hormone transportGO:00099141210.036
reactive oxygen species biosynthetic processGO:190340980.036
response to insulinGO:00328681330.036
reproductive system developmentGO:00614581280.035
cellular amino acid biosynthetic processGO:0008652320.035
positive regulation of transportGO:00510502450.035
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.035
norepinephrine secretionGO:0048243160.035
positive regulation of secretionGO:00510471400.035
glial cell differentiationGO:0010001650.035
neuron projection developmentGO:00311752730.034
cell adhesionGO:00071551100.034
steroid biosynthetic processGO:0006694480.034
regulation of excretionGO:0044062210.034
regulation of behaviorGO:0050795610.034
response to activityGO:0014823730.034
immune responseGO:00069551040.034
homeostatic processGO:00425923310.033
regulation of defense responseGO:0031347680.033
cellular amine metabolic processGO:0044106380.033
vesicle mediated transportGO:00161921810.033
action potentialGO:0001508540.033
mesoderm developmentGO:000749820.033
hepatocyte proliferationGO:007257430.033
organonitrogen compound biosynthetic processGO:19015661670.033
stress activated protein kinase signaling cascadeGO:0031098370.032
cellular response to growth factor stimulusGO:00713631620.032
response to transition metal nanoparticleGO:19902671220.032
regulation of hydrolase activityGO:00513361430.032
regulation of cellular ketone metabolic processGO:0010565270.032
positive regulation of catalytic activityGO:00430851840.032
cell growthGO:00160491040.032
positive regulation of neuron differentiationGO:00456661260.032
response to mechanical stimulusGO:00096121340.031
organ formationGO:004864530.031
regulation of calcium ion transportGO:0051924770.031
response to oxygen levelsGO:00704822650.031
cellular response to organonitrogen compoundGO:00714171970.031
regulation of renal sodium excretionGO:0035813200.031
response to cesium ionGO:001016420.031
response to lipopolysaccharideGO:00324961910.031
negative regulation of signalingGO:00230571570.031
regulation of cell projection organizationGO:00313441750.031
signal releaseGO:00230611450.031
cell migrationGO:00164771970.030
programmed cell deathGO:00125013920.030
Rat
regulation of neuron projection developmentGO:00109751610.030
brain developmentGO:00074202470.030
negative regulation of cell deathGO:00605482290.030
male sex differentiationGO:0046661640.030
regulation of signal transductionGO:00099663180.030
positive regulation of cellular protein metabolic processGO:00322701670.030
peptide transportGO:0015833970.030
positive regulation of intracellular signal transductionGO:19025331380.030
sexual reproductionGO:00199531480.030
response to biotic stimulusGO:00096072260.030
regulation of immune system processGO:00026821230.029
regulation of programmed cell deathGO:00430673410.029
Rat
biological adhesionGO:00226101100.029
organic substance catabolic processGO:19015753160.029
digestive system developmentGO:0055123410.029
proteolysisGO:00065081750.029
cell morphogenesisGO:00009021420.029
positive regulation of peptide hormone secretionGO:0090277500.029
cell activationGO:0001775970.028
positive regulation of signalingGO:00230562700.028
positive regulation of immune system processGO:0002684900.028
regulation of acute inflammatory responseGO:0002673230.028
negative regulation of epithelial cell proliferationGO:0050680160.028
response to vitamin b6GO:003451610.028
regulation of peptide transportGO:0090087870.028
hemostasisGO:0007599260.028
Rat
renal system developmentGO:0072001670.028
lipid metabolic processGO:00066292830.027
metal ion transportGO:00300012890.027
response to external biotic stimulusGO:00432072210.027
regulation of cell developmentGO:00602842630.027
small molecule biosynthetic processGO:00442831240.027
carbohydrate derivative metabolic processGO:19011353460.027
heterotypic cell cell adhesionGO:003411320.027
regulation of mapk cascadeGO:00434081160.027
cellular response to estradiol stimulusGO:0071392160.027
cellular response to interleukin 6GO:007135490.027
cerebral cortex developmentGO:0021987180.026
positive regulation of secretion by cellGO:19035321280.026
amide transportGO:00428861050.026
cellular catabolic processGO:00442482950.026
protein oligomerizationGO:00512591910.026
negative regulation of protein metabolic processGO:00512481140.026
regulation of cell adhesionGO:0030155520.026
lipid transportGO:0006869610.026
protein processingGO:0016485680.026
positive regulation of signal transductionGO:00099671750.026
plasminogen activationGO:003163920.026
sensory organ developmentGO:0007423740.026
regulation of reactive oxygen species metabolic processGO:2000377260.026
cell part morphogenesisGO:00329901230.026
cellular response to hexose stimulusGO:0071331650.026
gamete generationGO:00072761240.025
steroid metabolic processGO:0008202730.025
heart growthGO:0060419200.025
positive regulation of hormone secretionGO:0046887650.025
cellular response to cytokine stimulusGO:00713451270.025
positive regulation of cell differentiationGO:00455972170.024
rna metabolic processGO:00160704060.024
hepaticobiliary system developmentGO:0061008900.024
vascular process in circulatory systemGO:0003018960.024
amine metabolic processGO:0009308380.024
regulation of transcription dna templatedGO:00063553740.024
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.024
organelle localizationGO:0051640550.024
cellular sodium ion homeostasisGO:000688340.024
regulation of response to woundingGO:1903034690.023
stress activated mapk cascadeGO:0051403350.023
gland morphogenesisGO:0022612120.023
g protein coupled receptor signaling pathwayGO:00071862420.023
protein homooligomerizationGO:0051260910.023
negative regulation of neuron deathGO:1901215690.023
multicellular organism reproductionGO:00325042330.023
epithelial cell proliferationGO:0050673540.023
neuron projection morphogenesisGO:00488121220.023
cellular cation homeostasisGO:00300031800.023
secretion by cellGO:00329402480.023
positive regulation of molecular functionGO:00440932300.023
positive regulation of tolerance inductionGO:000264510.023
negative regulation of cellular metabolic processGO:00313242810.022
metal ion homeostasisGO:00550651860.022
synaptic transmissionGO:00072682350.022
cell projection morphogenesisGO:00488581230.022
cellular ketone metabolic processGO:0042180510.022
development of primary sexual characteristicsGO:00451371070.022
mesoderm morphogenesisGO:004833210.022
cerebral cortex tangential migrationGO:002180010.022
organic acid biosynthetic processGO:0016053830.022
regulation of inflammatory responseGO:0050727480.022
response to retinoic acidGO:0032526630.022
response to mineralocorticoidGO:0051385490.021
heart developmentGO:0007507720.021
response to testosteroneGO:0033574550.021
organic acid transportGO:00158491160.021
cellular component morphogenesisGO:00329891550.021
positive regulation of renal sodium excretionGO:0035815100.021
gliogenesisGO:0042063930.021
response to carbohydrateGO:00097431830.021
catenin import into nucleusGO:003541110.021
angiogenesisGO:0001525530.021
cellular calcium ion homeostasisGO:00068741600.021
regulation of hormone secretionGO:00468831060.021
defense response to gram negative bacteriumGO:005082930.021
intracellular transportGO:00469071850.020
protein maturationGO:0051604680.020
positive regulation of reactive oxygen species metabolic processGO:2000379160.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
multicellular organismal reproductive processGO:00486092330.020
regulation of protein maturationGO:1903317500.020
positive regulation of nucleobase containing compound metabolic processGO:00459353190.020
carbohydrate homeostasisGO:0033500750.020
ossificationGO:0001503700.020
ovulation cycle processGO:0022602500.020
regulation of cellular amine metabolic processGO:003323880.020
learning or memoryGO:0007611900.020
response to dexamethasoneGO:0071548490.020
monocarboxylic acid metabolic processGO:00327871520.020
positive regulation of blood coagulationGO:003019440.020
cell morphogenesis involved in differentiationGO:00009041190.019
organ regenerationGO:00311001010.019
negative regulation of fibrinolysisGO:005191820.019
digestive tract developmentGO:0048565390.019
cellular divalent inorganic cation homeostasisGO:00725031620.019
regulation of intracellular transportGO:0032386650.019
cellular response to dexamethasone stimulusGO:0071549360.019
response to chromateGO:004668730.019
tube developmentGO:0035295890.019
response to ionizing radiationGO:0010212590.019
regulation of membrane potentialGO:00423911100.019
negative regulation of serine type peptidase activityGO:190257210.019
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.019
response to calcium ionGO:0051592590.019
negative regulation of nitrogen compound metabolic processGO:00511721610.018
regulation of protein processingGO:0070613500.018
positive regulation of reactive oxygen species biosynthetic processGO:190342820.018
positive regulation of phosphorylationGO:00423271770.018
smooth muscle cell proliferationGO:0048659770.018
response to starvationGO:0042594590.018
neuron developmentGO:00486662860.018
regulation of peptide secretionGO:0002791820.018
regulation of cellular amino acid metabolic processGO:000652120.018
positive regulation of protein modification processGO:00314011420.018
cellular response to campGO:0071320260.018
sterol homeostasisGO:005509230.018
bone developmentGO:0060348250.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
regulation of cell cell adhesionGO:0022407140.017
positive regulation of phosphate metabolic processGO:00459372620.017
positive regulation of mapk cascadeGO:0043410920.017
positive regulation of homeostatic processGO:0032846490.017
positive regulation of apoptotic processGO:00430651540.017
Rat
sex differentiationGO:00075481130.017
cellular response to glucose stimulusGO:0071333650.017
transmembrane transportGO:00550854120.017
long chain fatty acid metabolic processGO:0001676320.017
negative regulation of endopeptidase activityGO:0010951360.017
cellular response to carbohydrate stimulusGO:0071322720.017
cellular glucose homeostasisGO:0001678660.017
response to growth factorGO:00708481890.017
endocrine system developmentGO:0035270300.017
spermatogenesisGO:0007283990.017
response to ethanolGO:00454711620.017
cardiovascular system developmentGO:00723581340.017
gastrulationGO:000736920.017
diencephalon developmentGO:0021536210.017
cellular amino acid metabolic processGO:00065201070.017
blood vessel developmentGO:0001568690.017
organic anion transportGO:00157111320.016
regulation of homeostatic processGO:00328441010.016
drinking behaviorGO:0042756110.016
regulation of heterotypic cell cell adhesionGO:003411420.016
organ growthGO:0035265240.016
positive regulation of rna biosynthetic processGO:19026801970.016
exocytosisGO:0006887600.016
glycerolipid metabolic processGO:0046486670.016
peptidyl amino acid modificationGO:00181931260.016
heart morphogenesisGO:000300730.016
catabolic processGO:00090563510.016
striated muscle tissue developmentGO:0014706580.016
regulation of transferase activityGO:00513381230.016
negative regulation of protein processingGO:0010955470.016
alpha amino acid biosynthetic processGO:1901607230.016
muscle cell differentiationGO:0042692520.016
rna biosynthetic processGO:00327743800.016
protein activation cascadeGO:0072376120.016
dna metabolic processGO:0006259960.016
spinal cord developmentGO:0021510270.016
pallium developmentGO:0021543420.016
regulation of neurological system processGO:0031644430.016
positive regulation of blood circulationGO:1903524650.016
calcium ion transportGO:00068161310.015
response to decreased oxygen levelsGO:00362932370.015
divalent inorganic cation transportGO:00725111340.015
negative regulation of cellular protein metabolic processGO:00322691060.015
positive regulation of cell projection organizationGO:00313461110.015
calcium ion homeostasisGO:00550741620.015
peptide secretionGO:0002790860.015
exogenous drug catabolic processGO:004273810.015
cytosolic calcium ion homeostasisGO:00514801400.015
nucleobase containing small molecule metabolic processGO:00550863160.015
extracellular matrix organizationGO:0030198130.015
post embryonic developmentGO:000979160.015
chemosensory behaviorGO:000763520.015
negative regulation of cell differentiationGO:0045596990.015
positive regulation of erk1 and erk2 cascadeGO:0070374290.015
response to temperature stimulusGO:0009266940.015
camera type eye developmentGO:0043010480.015
positive regulation of nitric oxide biosynthetic processGO:0045429140.015
cognitionGO:0050890920.015
acylglycerol metabolic processGO:0006639210.015
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.015
axonogenesisGO:0007409710.015
establishment of protein localizationGO:00451841410.015
positive regulation of neuron projection developmentGO:0010976990.015
regulation of cell morphogenesis involved in differentiationGO:0010769720.015
neuronal action potentialGO:0019228350.015
cytoplasmic transportGO:00164821150.014
axis specificationGO:000979840.014
regulation of phosphorylationGO:00423252480.014
response to progesteroneGO:0032570480.014
erk1 and erk2 cascadeGO:0070371480.014
serine family amino acid biosynthetic processGO:000907040.014
response to lead ionGO:0010288330.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
maintenance of locationGO:0051235170.014
protein transportGO:00150311320.014
cardiac chamber developmentGO:000320510.014
nucleoside phosphate metabolic processGO:00067532830.014
epithelium developmentGO:0060429960.014
protein phosphorylationGO:00064683450.014
axon ensheathmentGO:0008366400.014
negative regulation of innate immune responseGO:004582440.014
phenol containing compound metabolic processGO:0018958300.014

C8b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.029
disease of anatomical entityDOID:700.029
vascular diseaseDOID:17800.029
disease of cellular proliferationDOID:1456600.025
organ system cancerDOID:005068600.025
cancerDOID:16200.025
disease of metabolismDOID:001466700.025
gastrointestinal system cancerDOID:311900.018
immune system diseaseDOID:291400.017
blood coagulation diseaseDOID:124700.017
hematopoietic system diseaseDOID:7400.017
inherited blood coagulation diseaseDOID:221400.017