Rattus norvegicus

17 known processes

Cadm1

cell adhesion molecule 1

(Aliases: Igsf4a,Necl-2,sgigsf,TSLC1)

Cadm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component morphogenesisGO:00329891550.399
regulation of cellular component organizationGO:00511283680.384
cell morphogenesis involved in neuron differentiationGO:00486671060.371
neuron differentiationGO:00301823680.354
neuron projection developmentGO:00311752730.310
neuron developmentGO:00486662860.292
cell projection organizationGO:00300303020.287
axon developmentGO:0061564960.277
positive regulation of cellular component organizationGO:00511302000.271
cell projection morphogenesisGO:00488581230.269
cell part morphogenesisGO:00329901230.263
regulation of multicellular organismal developmentGO:20000263760.254
neuron projection morphogenesisGO:00488121220.244
cell morphogenesis involved in differentiationGO:00009041190.235
locomotionGO:00400112370.222
positive regulation of multicellular organismal processGO:00512403870.220
Human
intracellular signal transductionGO:00355563140.197
regulation of cell differentiationGO:00455953200.196
regulation of nervous system developmentGO:00519602640.196
cell migrationGO:00164771970.193
regulation of signal transductionGO:00099663180.174
regulation of molecular functionGO:00650093980.172
cell morphogenesisGO:00009021420.164
axonogenesisGO:0007409710.159
brain developmentGO:00074202470.157
enzyme linked receptor protein signaling pathwayGO:00071671160.152
cellular component movementGO:00069282480.149
regulation of cell developmentGO:00602842630.146
secretionGO:00469033070.146
Human
positive regulation of developmental processGO:00510942830.146
regulation of phosphorylationGO:00423252480.145
regulation of cell morphogenesis involved in differentiationGO:0010769720.140
regulation of neurogenesisGO:00507672470.139
regulation of intracellular signal transductionGO:19025312180.133
regulation of neuron projection developmentGO:00109751610.132
anatomical structure morphogenesisGO:00096532980.130
motor neuron axon guidanceGO:000804510.125
regulation of cell morphogenesisGO:0022604770.124
regulation of phosphate metabolic processGO:00192203490.121
cellular component biogenesisGO:00440853680.119
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.116
regulation of phosphorus metabolic processGO:00511743490.110
positive regulation of nervous system developmentGO:00519621780.110
regulation of cell projection organizationGO:00313441750.109
central nervous system developmentGO:00074173110.108
carboxylic acid metabolic processGO:00197522890.106
head developmentGO:00603222470.104
cellular amino acid metabolic processGO:00065201070.103
biological adhesionGO:00226101100.100
cellular response to endogenous stimulusGO:00714953770.099
oxoacid metabolic processGO:00434362900.097
protein phosphorylationGO:00064683450.097
apoptotic processGO:00069153810.094
localization of cellGO:00516742020.094
regulation of anatomical structure morphogenesisGO:00226031410.093
regulation of protein metabolic processGO:00512462890.093
cellular component assemblyGO:00226073600.092
cell motilityGO:00488702020.089
organic acid metabolic processGO:00060822920.084
regulation of programmed cell deathGO:00430673410.084
positive regulation of transportGO:00510502450.084
Human
vesicle mediated transportGO:00161921810.082
regulation of cellular component movementGO:00512701500.081
cell adhesionGO:00071551100.081
peptidyl amino acid modificationGO:00181931260.081
negative regulation of cell proliferationGO:00082851190.079
tissue developmentGO:00098882520.078
taxisGO:0042330670.078
response to woundingGO:00096112540.078
programmed cell deathGO:00125013920.077
positive regulation of neurogenesisGO:00507691650.077
negative regulation of metabolic processGO:00098923310.077
regulation of catalytic activityGO:00507903040.075
regulation of cellular amino acid metabolic processGO:000652120.073
regulation of cellular amine metabolic processGO:003323880.071
axon guidanceGO:0007411240.071
amine metabolic processGO:0009308380.069
transcription dna templatedGO:00063513770.067
regulation of cellular protein metabolic processGO:00322682670.067
positive regulation of cell communicationGO:00106472710.067
chemotaxisGO:0006935660.066
negative regulation of cellular metabolic processGO:00313242810.066
regulation of locomotionGO:00400121480.066
regulation of cell proliferationGO:00421273590.065
negative regulation of signalingGO:00230571570.065
regulation of protein phosphorylationGO:00019321830.064
cellular ketone metabolic processGO:0042180510.063
negative regulation of response to stimulusGO:00485851550.062
cellular response to oxygen containing compoundGO:19017013860.060
regulation of apoptotic processGO:00429813350.060
regulation of cellular ketone metabolic processGO:0010565270.060
organelle organizationGO:00069962660.058
protein complex biogenesisGO:00702712630.058
positive regulation of cell differentiationGO:00455972170.058
cellular response to insulin stimulusGO:0032869810.058
regulation of cell migrationGO:00303341280.058
growthGO:00400071650.058
macromolecular complex subunit organizationGO:00439333390.057
positive regulation of biosynthetic processGO:00098913190.057
developmental growthGO:00485891000.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.056
cellular response to hormone stimulusGO:00328702470.056
regulation of neuron differentiationGO:00456642080.055
regulation of axonogenesisGO:0050770370.055
regulation of nucleic acid templated transcriptionGO:19035063800.055
positive regulation of gene expressionGO:00106282440.054
negative regulation of cell communicationGO:00106481580.053
negative regulation of multicellular organismal processGO:00512412030.053
cell growthGO:00160491040.052
positive regulation of nitrogen compound metabolic processGO:00511733340.052
synaptic growth at neuromuscular junctionGO:005112410.052
negative regulation of gene expressionGO:00106291990.051
cellular amine metabolic processGO:0044106380.051
positive regulation of neuron differentiationGO:00456661260.051
regulation of transcription dna templatedGO:00063553740.050
cellular response to peptide hormone stimulusGO:00713751200.050
rna biosynthetic processGO:00327743800.049
positive regulation of cell projection organizationGO:00313461110.049
regulation of cellular localizationGO:00603412630.049
Human
positive regulation of intracellular signal transductionGO:19025331380.049
positive regulation of response to stimulusGO:00485842850.047
Human
carbohydrate derivative metabolic processGO:19011353460.047
positive regulation of neuron projection developmentGO:0010976990.047
regenerationGO:00310991630.046
positive regulation of cell developmentGO:00107201760.046
protein localizationGO:00081041910.046
Human
protein complex assemblyGO:00064612630.046
regulation of protein modification processGO:00313991940.046
single organism organelle organizationGO:19025891800.045
positive regulation of phosphorus metabolic processGO:00105622620.045
reproductive processGO:00224143720.045
secretion by cellGO:00329402480.044
Human
negative regulation of molecular functionGO:00440921330.044
regulation of protein kinase activityGO:00458591050.044
exocytosisGO:0006887600.042
macromolecular complex assemblyGO:00650032730.042
transcription from rna polymerase ii promoterGO:00063662520.041
behaviorGO:00076102050.041
positive regulation of signalingGO:00230562700.041
response to metal ionGO:00100382530.040
cation transportGO:00068123820.040
regulation of cellular component biogenesisGO:0044087860.040
negative regulation of protein metabolic processGO:00512481140.040
purine ribonucleoside triphosphate metabolic processGO:00092051400.040
synapse organizationGO:0050808460.039
neuron deathGO:00709971270.039
positive regulation of cell proliferationGO:00082842490.039
response to peptide hormoneGO:00434342780.039
regulation of rna metabolic processGO:00512523910.039
positive regulation of molecular functionGO:00440932300.037
forebrain developmentGO:0030900980.037
response to cytokineGO:00340972150.037
cellular response to organonitrogen compoundGO:00714171970.036
negative regulation of signal transductionGO:0009968830.036
positive regulation of cell migrationGO:0030335960.036
multi organism reproductive processGO:00447032620.036
single organism catabolic processGO:00447122830.035
neuron projection guidanceGO:0097485240.035
regulation of mapk cascadeGO:00434081160.035
positive regulation of rna biosynthetic processGO:19026801970.035
catabolic processGO:00090563510.035
response to peptideGO:19016522920.035
peptidyl tyrosine phosphorylationGO:0018108720.035
regulation of growthGO:00400081050.035
response to inorganic substanceGO:00100353770.035
positive regulation of cellular biosynthetic processGO:00313282950.035
response to growth factorGO:00708481890.035
embryonic skeletal system morphogenesisGO:004870430.034
organic substance catabolic processGO:19015753160.034
regulation of cell motilityGO:20001451310.034
response to oxygen levelsGO:00704822650.034
negative regulation of macromolecule metabolic processGO:00106052600.034
regulation of vesicle mediated transportGO:0060627810.034
dendrite morphogenesisGO:0048813430.034
epithelium developmentGO:0060429960.034
response to estrogenGO:00436272320.033
macromolecule localizationGO:00330362520.033
Human
cellular response to nitrogen compoundGO:19016992100.033
homeostatic processGO:00425923310.032
rna metabolic processGO:00160704060.032
regulation of kinase activityGO:00435491170.032
positive regulation of cell motilityGO:2000147970.032
neural crest cell differentiationGO:001403320.032
metal ion transportGO:00300012890.032
transmembrane transportGO:00550854120.032
positive regulation of cellular amine metabolic processGO:003324030.032
negative regulation of phosphate metabolic processGO:0045936800.032
positive regulation of protein metabolic processGO:00512471780.032
cellular response to stressGO:00335542690.032
regulation of rna biosynthetic processGO:20011413810.032
positive regulation of cellular amino acid metabolic processGO:004576410.031
anterior posterior pattern specificationGO:000995210.031
protein complex subunit organizationGO:00718223020.031
cellular cation homeostasisGO:00300031800.031
positive regulation of locomotionGO:00400171020.031
regulation of secretion by cellGO:19035302080.031
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.031
positive regulation of signal transductionGO:00099671750.031
regulation of response to external stimulusGO:00321011060.030
multicellular organism growthGO:003526410.030
regulation of transferase activityGO:00513381230.030
single organism intracellular transportGO:19025821660.030
cellular chemical homeostasisGO:00550822470.030
cell type specific apoptotic processGO:00972851340.029
neuron apoptotic processGO:0051402880.029
negative regulation of developmental processGO:00510931250.029
response to carbohydrateGO:00097431830.029
positive regulation of cellular protein metabolic processGO:00322701670.029
peptidyl tyrosine modificationGO:0018212720.029
positive regulation of programmed cell deathGO:00430681570.029
regulation of neuron deathGO:19012141150.029
positive regulation of catalytic activityGO:00430851840.029
positive regulation of secretion by cellGO:19035321280.028
Human
positive regulation of apoptotic processGO:00430651540.028
positive regulation of cell deathGO:00109421840.028
central nervous system neuron axonogenesisGO:002195510.028
neural crest cell developmentGO:001403220.028
signal transduction by phosphorylationGO:00230141440.028
multicellular organism reproductionGO:00325042330.027
positive regulation of rna metabolic processGO:00512542030.027
chemical homeostasisGO:00488782920.027
agingGO:00075682410.027
regulation of cell growthGO:0001558850.027
embryonic pattern specificationGO:000988010.027
response to alkaloidGO:00432791320.027
reproductive structure developmentGO:00486081280.027
endocytosisGO:0006897840.027
nucleic acid templated transcriptionGO:00976593790.027
ribose phosphate metabolic processGO:00196932350.026
positive regulation of phosphorylationGO:00423271770.026
reproductionGO:00000032450.026
divalent inorganic cation transportGO:00725111340.026
mapk cascadeGO:00001651400.026
positive regulation of cellular component biogenesisGO:0044089550.026
response to hexoseGO:00097461440.025
dendrite developmentGO:0016358720.025
multicellular organismal reproductive processGO:00486092330.025
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
response to decreased oxygen levelsGO:00362932370.025
embryonic skeletal system developmentGO:004870630.025
neurological system processGO:00508772190.025
lipid metabolic processGO:00066292830.024
regulation of hydrolase activityGO:00513361430.024
positive regulation of secretionGO:00510471400.024
Human
sexual reproductionGO:00199531480.024
gonad developmentGO:00084061040.024
cellular lipid metabolic processGO:00442552080.024
cellular response to organic cyclic compoundGO:00714072020.023
response to extracellular stimulusGO:00099913800.023
negative regulation of neuron differentiationGO:0045665620.023
positive regulation of transcription dna templatedGO:00458931970.023
small gtpase mediated signal transductionGO:0007264360.023
negative regulation of neurogenesisGO:0050768780.023
neuron recognitionGO:000803890.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
organophosphate metabolic processGO:00196373700.022
negative regulation of cellular protein metabolic processGO:00322691060.022
regulation of response to stressGO:00801341260.022
Human
ion homeostasisGO:00508012120.022
regulation of developmental growthGO:0048638450.022
response to molecule of bacterial originGO:00022371940.022
positive regulation of mapk cascadeGO:0043410920.022
regulation of system processGO:00440572080.022
positive regulation of cellular component movementGO:00512721020.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
dephosphorylationGO:0016311980.022
negative regulation of cell differentiationGO:0045596990.022
single organism reproductive processGO:00447022970.022
regulation of canonical wnt signaling pathwayGO:006082840.022
synapse assemblyGO:0007416290.021
response to purine containing compoundGO:00140741260.021
regulation of secretionGO:00510462240.021
Human
negative regulation of cell deathGO:00605482290.021
bmp signaling pathwayGO:003050940.021
regulation of cellular catabolic processGO:00313291010.021
regulation of protein localizationGO:0032880810.021
Human
reactive oxygen species metabolic processGO:0072593370.021
response to nutrientGO:00075842480.021
nitrogen compound transportGO:00717052290.021
single organism biosynthetic processGO:00447113420.021
immune system processGO:00023762040.020
Human
response to axon injuryGO:0048678590.020
negative regulation of programmed cell deathGO:00430691830.020
regulation of purine nucleotide metabolic processGO:19005421150.020
cellular catabolic processGO:00442482950.020
regulation of cell adhesionGO:0030155520.020
positive regulation of protein kinase activityGO:0045860730.020
response to oxidative stressGO:00069791860.020
neural crest cell migrationGO:000175510.020
glycosyl compound metabolic processGO:19016571820.020
response to nutrient levelsGO:00316673700.020
regulation of ion transportGO:00432692450.020
regulation of synapse maturationGO:009012820.020
ion transmembrane transportGO:00342203650.020
response to hypoxiaGO:00016662310.020
muscle cell proliferationGO:0033002840.020
regulation of synapse structure and activityGO:0050803210.020
membrane organizationGO:0061024940.020
response to radiationGO:00093141370.020
epithelial cell differentiationGO:0030855710.019
response to monosaccharideGO:00342841590.019
cellular response to cytokine stimulusGO:00713451270.019
gamete generationGO:00072761240.019
eye developmentGO:0001654500.019
regulation of body fluid levelsGO:0050878900.019
cardiovascular system developmentGO:00723581340.019
purine ribonucleoside metabolic processGO:00461281680.019
response to bacteriumGO:00096172000.019
embryonic cranial skeleton morphogenesisGO:004870120.019
synaptic transmissionGO:00072682350.019
regulation of nucleotide metabolic processGO:00061401170.019
response to corticosteroidGO:00319602350.019
cellular response to growth factor stimulusGO:00713631620.019
circulatory system developmentGO:00723591340.019
protein dephosphorylationGO:0006470380.019
nucleobase containing compound catabolic processGO:00346551520.019
wound healingGO:00420601220.019
neuronal action potentialGO:0019228350.019
negative regulation of nervous system developmentGO:0051961790.019
learning or memoryGO:0007611900.019
cellular response to lipidGO:00713962010.019
negative regulation of apoptotic processGO:00430661810.019
developmental growth involved in morphogenesisGO:0060560330.018
response to glucoseGO:00097491360.018
cellular homeostasisGO:00197252520.018
signal releaseGO:00230611450.018
ras protein signal transductionGO:0007265290.018
positive regulation of kinase activityGO:0033674770.018
regulation of anatomical structure sizeGO:00900661350.018
cell cell signalingGO:00072673350.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
single organism behaviorGO:00447081300.018
regulation of response to woundingGO:1903034690.018
response to organophosphorusGO:00466831020.018
establishment of tissue polarityGO:000716420.017
circulatory system processGO:00030131830.017
response to glucocorticoidGO:00513842230.017
positive regulation of phosphate metabolic processGO:00459372620.017
regulation of map kinase activityGO:0043405530.017
divalent metal ion transportGO:00708381320.017
nucleotide metabolic processGO:00091172790.017
sex differentiationGO:00075481130.017
erbb signaling pathwayGO:0038127230.017
purine nucleoside metabolic processGO:00422781690.017
response to estradiolGO:00323551640.017
regulation of dendrite developmentGO:0050773590.017
regulation of organelle organizationGO:0033043800.017
dna metabolic processGO:0006259960.017
intracellular protein transportGO:0006886790.017
heart morphogenesisGO:000300730.017
development of primary sexual characteristicsGO:00451371070.017
negative regulation of phosphorus metabolic processGO:0010563800.017
transmission of nerve impulseGO:0019226420.017
purine ribonucleotide metabolic processGO:00091502270.017
gastrulationGO:000736920.016
positive regulation of protein modification processGO:00314011420.016
response to acid chemicalGO:00011012220.016
proteolysisGO:00065081750.016
neurotransmitter transportGO:0006836420.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
negative regulation of cellular component organizationGO:0051129830.016
monovalent inorganic cation transportGO:00156721720.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
regulation of metal ion transportGO:00109591180.016
gland developmentGO:00487321550.016
embryo developmentGO:0009790490.016
organ morphogenesisGO:0009887750.016
renal system developmentGO:0072001670.015
negative regulation of catalytic activityGO:00430861030.015
regulation of protein serine threonine kinase activityGO:0071900640.015
intracellular transportGO:00469071850.015
positive regulation of protein phosphorylationGO:00019341350.015
negative regulation of transcription dna templatedGO:00458921160.015
response to ethanolGO:00454711620.015
regulation of protein maturationGO:1903317500.015
cytoskeleton organizationGO:00070101110.015
ameboidal type cell migrationGO:0001667260.015
epidermal growth factor receptor signaling pathwayGO:0007173230.015
reproductive system developmentGO:00614581280.015
regulation of hormone levelsGO:00108171870.015
retinal ganglion cell axon guidanceGO:003129010.015
cellular response to peptideGO:19016531330.015
reactive oxygen species biosynthetic processGO:190340980.015
purine containing compound metabolic processGO:00725212530.015
regulation of cell cycleGO:0051726730.015
cognitionGO:0050890920.015
ribonucleoside metabolic processGO:00091191740.015
purine nucleotide metabolic processGO:00061632290.015
regulation of establishment of planar polarityGO:009017520.015
muscle tissue developmentGO:0060537580.015
negative regulation of transportGO:00510511360.015
calcium ion transportGO:00068161310.015
regulation of reactive oxygen species metabolic processGO:2000377260.014
purine containing compound catabolic processGO:00725231380.014
protein transportGO:00150311320.014
Human
metal ion homeostasisGO:00550651860.014
adult locomotory behaviorGO:000834440.014
sensory organ developmentGO:0007423740.014
positive regulation of synapse maturationGO:009012920.014
cell fate determinationGO:000170920.014
axon choice point recognitionGO:001619820.014
negative regulation of protein phosphorylationGO:0001933440.014
negative regulation of canonical wnt signaling pathwayGO:009009040.014
cellular nitrogen compound catabolic processGO:00442701630.014
axis specificationGO:000979840.014
regulation of neuron apoptotic processGO:0043523830.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
anion transportGO:00068201780.014
negative regulation of phosphorylationGO:0042326570.014
synaptic vesicle endocytosisGO:004848840.014
positive regulation of growthGO:0045927550.014
nucleoside phosphate metabolic processGO:00067532830.014
cation homeostasisGO:00550801950.014
lipid biosynthetic processGO:00086101280.014
cellular calcium ion homeostasisGO:00068741600.014
positive regulation of hydrolase activityGO:0051345860.013
cellular ion homeostasisGO:00068731840.013
regulation of membrane potentialGO:00423911100.013
regulation of cellular component sizeGO:0032535510.013
cell cycleGO:00070491010.013
purine ribonucleoside catabolic processGO:00461301240.013
positive regulation of protein transportGO:0051222410.013
Human
organ regenerationGO:00311001010.013
negative regulation of cell developmentGO:0010721820.013
positive regulation of neuron deathGO:1901216430.013
blood circulationGO:00080151830.013
multicellular organismal signalingGO:0035637440.013
response to ketoneGO:19016541820.013
response to toxic substanceGO:00096361330.013
asymmetric protein localizationGO:000810520.013
divalent inorganic cation homeostasisGO:00725071650.013
protein autophosphorylationGO:0046777660.013
regulation of axon extensionGO:0030516240.013
regulation of synaptic transmissionGO:00508041410.013
regulation of endocytosisGO:0030100420.013
carbohydrate derivative catabolic processGO:19011361470.013
organonitrogen compound catabolic processGO:19015651790.013
regulation of proteasomal protein catabolic processGO:006113640.013
purine ribonucleotide catabolic processGO:00091541360.013
response to reactive oxygen speciesGO:00003021200.013
eye morphogenesisGO:004859240.012
ribonucleotide catabolic processGO:00092611360.012
inorganic ion transmembrane transportGO:00986602290.012
positive regulation of endocytosisGO:0045807280.012
cellular response to alcoholGO:0097306870.012
cellular protein localizationGO:00346131220.012
heart developmentGO:0007507720.012
negative regulation of cell projection organizationGO:0031345500.012
multi multicellular organism processGO:00447061380.012
response to insulinGO:00328681330.012
positive regulation of nucleotide metabolic processGO:0045981910.012
cell cycle processGO:0022402570.012
carboxylic acid biosynthetic processGO:0046394830.012
regulation of cytoskeleton organizationGO:0051493490.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
regulation of cellular response to stressGO:0080135490.012
regulation of catabolic processGO:00098941130.012
gliogenesisGO:0042063930.012
cellular macromolecular complex assemblyGO:0034622580.012
regulation of immune system processGO:00026821230.012
Human
nucleoside metabolic processGO:00091161790.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
mesoderm developmentGO:000749820.012
ribonucleoside triphosphate catabolic processGO:00092031220.012
nucleoside phosphate catabolic processGO:19012921400.012
negative regulation of neuron projection developmentGO:0010977460.012
glucose homeostasisGO:0042593750.012
negative regulation of biosynthetic processGO:00098901680.012
response to campGO:0051591910.012
positive regulation of reactive oxygen species metabolic processGO:2000379160.012
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.012
epithelium migrationGO:0090132190.012
striated muscle tissue developmentGO:0014706580.011
establishment of protein localizationGO:00451841410.011
Human
nucleobase containing small molecule metabolic processGO:00550863160.011
kidney developmentGO:0001822670.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
protein oligomerizationGO:00512591910.011
nucleoside catabolic processGO:00091641260.011
nucleoside triphosphate catabolic processGO:00091431230.011
retina morphogenesis in camera type eyeGO:006004210.011
reactive nitrogen species metabolic processGO:200105710.011
urogenital system developmentGO:0001655780.011
organic acid biosynthetic processGO:0016053830.011
actin filament based processGO:0030029860.011
response to temperature stimulusGO:0009266940.011
response to interleukin 1GO:0070555550.011
male gamete generationGO:0048232990.011

Cadm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019
organ system cancerDOID:005068600.017
central nervous system diseaseDOID:33100.014
urinary system diseaseDOID:1800.012