IMP: Integrative Multi-species Prediction

Rattus norvegicus

20 known processes

Cpt1b

carnitine palmitoyltransferase 1b, muscle

(Aliases: M-CPTI,MGC93637,CPT-IB)

Entrez: 25756
RGD: 2397
Ensembl: ENSRNOG00000010438
UniProtKB: O70253

Process Predictions
Disease Predictions

Cpt1b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid metabolic process	GO:0019752	289	0.592	Yeast Rat
organic acid metabolic process	GO:0006082	292	0.283	Yeast Rat
lipid biosynthetic process	GO:0008610	128	0.195	Human
oxoacid metabolic process	GO:0043436	290	0.160	Yeast Rat
small molecule catabolic process	GO:0044282	59	0.144	Rat
lipid metabolic process	GO:0006629	283	0.144	Human Rat
transmembrane transport	GO:0055085	412	0.138
lipid oxidation	GO:0034440	30	0.130	Rat
secretion	GO:0046903	307	0.116	Rat
organic substance catabolic process	GO:1901575	316	0.116	Rat
cellular ketone metabolic process	GO:0042180	51	0.109	Rat
organic anion transport	GO:0015711	132	0.109
fatty acid oxidation	GO:0019395	29	0.108	Rat
glycerolipid metabolic process	GO:0046486	67	0.104	Human Rat
catabolic process	GO:0009056	351	0.104	Rat
nucleic acid templated transcription	GO:0097659	379	0.100
rna biosynthetic process	GO:0032774	380	0.088
multi organism reproductive process	GO:0044703	262	0.084
rna metabolic process	GO:0016070	406	0.083
cellular catabolic process	GO:0044248	295	0.081	Rat
lipid localization	GO:0010876	62	0.080
anion transport	GO:0006820	178	0.078
transcription dna templated	GO:0006351	377	0.077
cellular lipid catabolic process	GO:0044242	37	0.076	Rat
positive regulation of lipid catabolic process	GO:0050996	4	0.075	Rat
macromolecule localization	GO:0033036	252	0.072
amine metabolic process	GO:0009308	38	0.071	Human
response to growth factor	GO:0070848	189	0.065
cellular component biogenesis	GO:0044085	368	0.065	Rat
response to nutrient	GO:0007584	248	0.064	Rat
cellular amino acid metabolic process	GO:0006520	107	0.064
carboxylic acid catabolic process	GO:0046395	49	0.063	Rat
anatomical structure morphogenesis	GO:0009653	298	0.063
reproductive process	GO:0022414	372	0.061	Rat
carboxylic acid transport	GO:0046942	115	0.060
protein complex assembly	GO:0006461	263	0.059	Rat
regulation of cellular amine metabolic process	GO:0033238	8	0.059
response to insulin	GO:0032868	133	0.058
response to nutrient levels	GO:0031667	370	0.058	Rat
cellular amine metabolic process	GO:0044106	38	0.057	Human
regulation of hormone levels	GO:0010817	187	0.056	Rat
regulation of rna biosynthetic process	GO:2001141	381	0.056
lipid catabolic process	GO:0016042	46	0.055	Rat
regulation of secretion	GO:0051046	224	0.055	Rat
cellular lipid metabolic process	GO:0044255	208	0.055	Human Rat
regulation of cellular ketone metabolic process	GO:0010565	27	0.055	Rat
regulation of transcription dna templated	GO:0006355	374	0.052
regulation of programmed cell death	GO:0043067	341	0.052
monocarboxylic acid metabolic process	GO:0032787	152	0.052	Yeast Rat
organic acid catabolic process	GO:0016054	49	0.051	Rat
cellular component assembly	GO:0022607	360	0.050	Rat
regulation of phagocytosis engulfment	GO:0060099	4	0.047
response to inorganic substance	GO:0010035	377	0.047
gland development	GO:0048732	155	0.046
single organism biosynthetic process	GO:0044711	342	0.046	Human Rat
regulation of rna metabolic process	GO:0051252	391	0.046
cellular response to oxygen containing compound	GO:1901701	386	0.046	Rat
response to peptide	GO:1901652	292	0.045
positive regulation of phagocytosis engulfment	GO:0060100	4	0.044
single organism catabolic process	GO:0044712	283	0.044	Rat
response to extracellular stimulus	GO:0009991	380	0.044	Rat
regulation of cellular amino acid metabolic process	GO:0006521	2	0.043
regulation of cell differentiation	GO:0045595	320	0.042
monocarboxylic acid transport	GO:0015718	52	0.041
amide transport	GO:0042886	105	0.041	Rat
organelle organization	GO:0006996	266	0.041
fatty acid catabolic process	GO:0009062	26	0.040	Rat
nitrogen compound transport	GO:0071705	229	0.040	Rat
immune system process	GO:0002376	204	0.040
cellular response to endogenous stimulus	GO:0071495	377	0.040
cellular response to insulin stimulus	GO:0032869	81	0.040
protein complex subunit organization	GO:0071822	302	0.040	Rat
homeostatic process	GO:0042592	331	0.040
carbohydrate derivative metabolic process	GO:1901135	346	0.040
nucleoside phosphate metabolic process	GO:0006753	283	0.039
organophosphate metabolic process	GO:0019637	370	0.039	Human
fatty acid metabolic process	GO:0006631	99	0.039	Rat
response to peptide hormone	GO:0043434	278	0.039
central nervous system development	GO:0007417	311	0.038
regulation of nucleic acid templated transcription	GO:1903506	380	0.038
positive regulation of multicellular organismal process	GO:0051240	387	0.038
long chain fatty acid metabolic process	GO:0001676	32	0.037	Rat
multicellular organism reproduction	GO:0032504	233	0.036	Rat
reproduction	GO:0000003	245	0.036	Rat
oxidation reduction process	GO:0055114	304	0.035	Rat
blood circulation	GO:0008015	183	0.034
single organism reproductive process	GO:0044702	297	0.033	Rat
regulation of molecular function	GO:0065009	398	0.033
regulation of cellular localization	GO:0060341	263	0.033	Rat
nucleobase containing small molecule metabolic process	GO:0055086	316	0.033
organonitrogen compound biosynthetic process	GO:1901566	167	0.032	Human
acylglycerol metabolic process	GO:0006639	21	0.032	Rat
positive regulation of phosphorus metabolic process	GO:0010562	262	0.032
heart morphogenesis	GO:0003007	3	0.031
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.031
negative regulation of gene expression	GO:0010629	199	0.030
response to metal ion	GO:0010038	253	0.030
cellular component morphogenesis	GO:0032989	155	0.030
multicellular organismal reproductive process	GO:0048609	233	0.029	Rat
response to decreased oxygen levels	GO:0036293	237	0.028	Rat
cellular response to hormone stimulus	GO:0032870	247	0.027
protein phosphorylation	GO:0006468	345	0.026
cell projection organization	GO:0030030	302	0.026
protein complex biogenesis	GO:0070271	263	0.026	Rat
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.026
nucleotide metabolic process	GO:0009117	279	0.026
negative regulation of metabolic process	GO:0009892	331	0.026
peptide transport	GO:0015833	97	0.025	Rat
positive regulation of transport	GO:0051050	245	0.025
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.025
positive regulation of cellular amine metabolic process	GO:0033240	3	0.025
sexual reproduction	GO:0019953	148	0.025
cardiovascular system development	GO:0072358	134	0.025
negative regulation of transport	GO:0051051	136	0.025
long chain fatty acid import	GO:0044539	1	0.025
negative regulation of apoptotic process	GO:0043066	181	0.025
muscle structure development	GO:0061061	87	0.025
macromolecular complex assembly	GO:0065003	273	0.025	Rat
peptidyl amino acid modification	GO:0018193	126	0.024
cellular response to peptide	GO:1901653	133	0.024
positive regulation of rna metabolic process	GO:0051254	203	0.024
regulation of phosphate metabolic process	GO:0019220	349	0.024
intracellular signal transduction	GO:0035556	314	0.024
potassium ion transmembrane transport	GO:0071805	71	0.024
positive regulation of biosynthetic process	GO:0009891	319	0.024
carboxylic acid biosynthetic process	GO:0046394	83	0.024
regulation of protein modification process	GO:0031399	194	0.024
regulation of catabolic process	GO:0009894	113	0.023	Rat
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.023
hormone transport	GO:0009914	121	0.022	Rat
signal release	GO:0023061	145	0.022	Rat
regulation of secretion by cell	GO:1903530	208	0.022	Rat
neutral lipid metabolic process	GO:0006638	21	0.022	Rat
single organism organelle organization	GO:1902589	180	0.022
developmental process involved in reproduction	GO:0003006	159	0.022	Rat
cellular response to lipid	GO:0071396	201	0.022	Rat
fatty acid transmembrane transport	GO:1902001	3	0.021
response to oxygen levels	GO:0070482	265	0.021	Rat
phosphatidylethanolamine metabolic process	GO:0046337	1	0.021	Human
regulation of hormone secretion	GO:0046883	106	0.021	Rat
positive regulation of developmental process	GO:0051094	283	0.021
regulation of phosphorus metabolic process	GO:0051174	349	0.020
cellular response to growth factor stimulus	GO:0071363	162	0.020
inorganic cation transmembrane transport	GO:0098662	202	0.020
response to lipopolysaccharide	GO:0032496	191	0.020
lipid storage	GO:0019915	1	0.020
positive regulation of cell differentiation	GO:0045597	217	0.020
organic acid transport	GO:0015849	116	0.020
secretion by cell	GO:0032940	248	0.020	Rat
vesicle mediated transport	GO:0016192	181	0.019
hormone secretion	GO:0046879	115	0.019	Rat
positive regulation of transcription dna templated	GO:0045893	197	0.019
response to hexose	GO:0009746	144	0.019
regulation of apoptotic process	GO:0042981	335	0.019
glycosyl compound metabolic process	GO:1901657	182	0.019
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.019
organophosphate biosynthetic process	GO:0090407	143	0.019	Human
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.019
negative regulation of macromolecule metabolic process	GO:0010605	260	0.018
negative regulation of multicellular organismal process	GO:0051241	203	0.018
regulation of catalytic activity	GO:0050790	304	0.018
positive regulation of fatty acid beta oxidation	GO:0032000	4	0.018	Rat
triglyceride metabolic process	GO:0006641	21	0.018	Rat
response to monosaccharide	GO:0034284	159	0.018
neuron development	GO:0048666	286	0.018
cellular response to organonitrogen compound	GO:0071417	197	0.018
behavior	GO:0007610	205	0.018	Rat
cellular response to peptide hormone stimulus	GO:0071375	120	0.018
response to carbohydrate	GO:0009743	183	0.018
cellular macromolecule localization	GO:0070727	122	0.018
regulation of peptide secretion	GO:0002791	82	0.018	Rat
membrane organization	GO:0061024	94	0.018
regulation of mapk cascade	GO:0043408	116	0.018
macromolecular complex subunit organization	GO:0043933	339	0.018	Rat
neuron projection development	GO:0031175	273	0.018
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.017
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017
cardiac conduction	GO:0061337	2	0.017
cellular response to nitrogen compound	GO:1901699	210	0.017
response to bacterium	GO:0009617	200	0.017	Zebrafish
regulation of peptide transport	GO:0090087	87	0.017	Rat
regulation of transferase activity	GO:0051338	123	0.017
phospholipid biosynthetic process	GO:0008654	29	0.017	Human
multicellular organism growth	GO:0035264	1	0.017
chemical homeostasis	GO:0048878	292	0.017
gamete generation	GO:0007276	124	0.017
response to glucose	GO:0009749	136	0.017
negative regulation of cellular metabolic process	GO:0031324	281	0.017
response to reactive oxygen species	GO:0000302	120	0.017
protein localization to organelle	GO:0033365	57	0.017
ion transmembrane transport	GO:0034220	365	0.017
regulation of nervous system development	GO:0051960	264	0.017
single organism intracellular transport	GO:1902582	166	0.017
spermatogenesis	GO:0007283	99	0.017
negative regulation of secretion by cell	GO:1903531	72	0.017
positive regulation of cell development	GO:0010720	176	0.017
monocarboxylic acid catabolic process	GO:0072329	28	0.017	Rat
reactive oxygen species metabolic process	GO:0072593	37	0.016
purine containing compound metabolic process	GO:0072521	253	0.016
regulation of protein phosphorylation	GO:0001932	183	0.016
organic hydroxy compound transport	GO:0015850	77	0.016
negative regulation of signaling	GO:0023057	157	0.016
biological adhesion	GO:0022610	110	0.016
response to wounding	GO:0009611	254	0.016
regeneration	GO:0031099	163	0.016
regulation of signal transduction	GO:0009966	318	0.016
cell cell signaling	GO:0007267	335	0.016	Rat
regulation of multicellular organismal development	GO:2000026	376	0.016
ras protein signal transduction	GO:0007265	29	0.016
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.015
response to purine containing compound	GO:0014074	126	0.015
negative regulation of developmental process	GO:0051093	125	0.015
cognition	GO:0050890	92	0.015	Rat
positive regulation of protein phosphorylation	GO:0001934	135	0.015
negative regulation of programmed cell death	GO:0043069	183	0.015
negative regulation of rna biosynthetic process	GO:1902679	118	0.015
positive regulation of protein modification process	GO:0031401	142	0.015
transcription from rna polymerase ii promoter	GO:0006366	252	0.015
negative regulation of cell death	GO:0060548	229	0.015
vitamin transport	GO:0051180	14	0.015
cell morphogenesis	GO:0000902	142	0.015
programmed cell death	GO:0012501	392	0.015
peptide hormone secretion	GO:0030072	84	0.015	Rat
regulation of neuron differentiation	GO:0045664	208	0.015
male gamete generation	GO:0048232	99	0.015
response to oxidative stress	GO:0006979	186	0.015
negative regulation of cell communication	GO:0010648	158	0.015
nucleobase containing compound catabolic process	GO:0034655	152	0.015
neuron differentiation	GO:0030182	368	0.015
positive regulation of ion transport	GO:0043270	94	0.015
carbohydrate derivative catabolic process	GO:1901136	147	0.015
regulation of membrane potential	GO:0042391	110	0.015
regulation of protein metabolic process	GO:0051246	289	0.014
ribose phosphate metabolic process	GO:0019693	235	0.014
cellular response to stress	GO:0033554	269	0.014
regulation of cellular component organization	GO:0051128	368	0.014
response to ketone	GO:1901654	182	0.014
cellular potassium ion transport	GO:0071804	72	0.014
circulatory system process	GO:0003013	183	0.014
cation transport	GO:0006812	382	0.014
protein localization	GO:0008104	191	0.014
ribonucleoside metabolic process	GO:0009119	174	0.014
brain development	GO:0007420	247	0.014
purine nucleotide metabolic process	GO:0006163	229	0.014
small molecule biosynthetic process	GO:0044283	124	0.014	Human
positive regulation of gene expression	GO:0010628	244	0.014
regulation of membrane repolarization	GO:0060306	1	0.014
protein oligomerization	GO:0051259	191	0.014	Rat
positive regulation of phosphate metabolic process	GO:0045937	262	0.014
cation transmembrane transport	GO:0098655	263	0.014
response to camp	GO:0051591	91	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
cell morphogenesis involved in differentiation	GO:0000904	119	0.014
fatty acid transport	GO:0015908	25	0.014
anterior posterior pattern specification	GO:0009952	1	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.013
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.013
regulation of peptide hormone secretion	GO:0090276	80	0.013	Rat
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.013
positive regulation of molecular function	GO:0044093	230	0.013
cellular protein localization	GO:0034613	122	0.013
muscle system process	GO:0003012	115	0.013
regulation of cellular protein metabolic process	GO:0032268	267	0.013
chromosome segregation	GO:0007059	2	0.013
regulation of body fluid levels	GO:0050878	90	0.013
canalicular bile acid transport	GO:0015722	5	0.013
regulation of response to external stimulus	GO:0032101	106	0.013
response to vitamin	GO:0033273	131	0.013
positive regulation of signal transduction	GO:0009967	175	0.013
response to molecule of bacterial origin	GO:0002237	194	0.013
heterocycle catabolic process	GO:0046700	167	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.013
negative regulation of hormone secretion	GO:0046888	46	0.013
neuron projection morphogenesis	GO:0048812	122	0.013
purine nucleoside metabolic process	GO:0042278	169	0.013
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013
regulation of fatty acid metabolic process	GO:0019217	18	0.013	Rat
sequestering of triglyceride	GO:0030730	1	0.013
response to external biotic stimulus	GO:0043207	221	0.012	Zebrafish
positive regulation of protein metabolic process	GO:0051247	178	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
neurological system process	GO:0050877	219	0.012	Rat
action potential	GO:0001508	54	0.012
apoptotic process	GO:0006915	381	0.012
response to estrogen	GO:0043627	232	0.012
regulation of protein serine threonine kinase activity	GO:0071900	64	0.012
glutamine family amino acid metabolic process	GO:0009064	15	0.012
maintenance of location	GO:0051235	17	0.012
positive regulation of fatty acid oxidation	GO:0046321	6	0.012	Rat
alcohol metabolic process	GO:0006066	77	0.012	Human
positive regulation of cellular protein metabolic process	GO:0032270	167	0.012
positive regulation of secretion	GO:0051047	140	0.012
phospholipid metabolic process	GO:0006644	61	0.012	Human
small gtpase mediated signal transduction	GO:0007264	36	0.011
muscle cell differentiation	GO:0042692	52	0.011
regulation of intracellular signal transduction	GO:1902531	218	0.011
cellular amino acid catabolic process	GO:0009063	21	0.011
regulation of phosphorylation	GO:0042325	248	0.011
regulation of neurogenesis	GO:0050767	247	0.011
regulation of lipid storage	GO:0010883	1	0.011
regulation of cell projection organization	GO:0031344	175	0.011
positive regulation of rna biosynthetic process	GO:1902680	197	0.011
anion transmembrane transport	GO:0098656	77	0.011
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.011
response to mechanical stimulus	GO:0009612	134	0.011
heart development	GO:0007507	72	0.011
cell adhesion	GO:0007155	110	0.011
response to ethanol	GO:0045471	162	0.011	Rat
positive regulation of cell communication	GO:0010647	271	0.011
metanephric comma shaped body morphogenesis	GO:0072278	2	0.011
cellular chemical homeostasis	GO:0055082	247	0.011
smooth muscle cell proliferation	GO:0048659	77	0.011
regulation of cell proliferation	GO:0042127	359	0.011
single organism cellular localization	GO:1902580	102	0.011
purine containing compound catabolic process	GO:0072523	138	0.011
striated muscle contraction	GO:0006941	44	0.011
nucleotide catabolic process	GO:0009166	139	0.011
peptide secretion	GO:0002790	86	0.011	Rat
regulation of neuron projection development	GO:0010975	161	0.011
monovalent inorganic cation transport	GO:0015672	172	0.011
defense response	GO:0006952	194	0.011
negative regulation of transcription dna templated	GO:0045892	116	0.011
neuronal action potential	GO:0019228	35	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
cellular polysaccharide metabolic process	GO:0044264	23	0.011
axis specification	GO:0009798	4	0.011
positive regulation of catalytic activity	GO:0043085	184	0.011
intracellular protein transport	GO:0006886	79	0.011
reproductive system development	GO:0061458	128	0.011	Rat
steroid biosynthetic process	GO:0006694	48	0.011
regulation of insulin secretion	GO:0050796	65	0.011	Rat
regulation of stem cell differentiation	GO:2000736	2	0.011
adult locomotory behavior	GO:0008344	4	0.011
organic cyclic compound catabolic process	GO:1901361	175	0.011
growth	GO:0040007	165	0.011	Rat
protein homooligomerization	GO:0051260	91	0.011	Rat
dna metabolic process	GO:0006259	96	0.011
hematopoietic progenitor cell differentiation	GO:0002244	2	0.011
membrane repolarization	GO:0086009	1	0.010
positive regulation of catabolic process	GO:0009896	78	0.010	Rat
response to vitamin e	GO:0033197	24	0.010
cellular response to molecule of bacterial origin	GO:0071219	56	0.010
reproductive structure development	GO:0048608	128	0.010	Rat
purine containing compound biosynthetic process	GO:0072522	85	0.010
positive regulation of phosphorylation	GO:0042327	177	0.010
regulation of cellular catabolic process	GO:0031329	101	0.010	Rat
cellular nitrogen compound catabolic process	GO:0044270	163	0.010
synaptic transmission	GO:0007268	235	0.010	Rat
cytoplasmic transport	GO:0016482	115	0.010
neuromuscular process	GO:0050905	2	0.010
regulation of fatty acid beta oxidation	GO:0031998	8	0.010	Rat
glycerol transport	GO:0015793	2	0.010
negative regulation of molecular function	GO:0044092	133	0.010
developmental growth	GO:0048589	100	0.010	Rat
circulatory system development	GO:0072359	134	0.010
insulin secretion	GO:0030073	69	0.010	Rat
regulation of cell development	GO:0060284	263	0.010
positive regulation of cellular catabolic process	GO:0031331	71	0.010	Rat
cofactor metabolic process	GO:0051186	95	0.010

Cpt1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability	Func Analog Org
myopathy	DOID:423	0.067	Human
muscular disease	DOID:0080000	0.067	Human
muscle tissue disease	DOID:66	0.067	Human
musculoskeletal system disease	DOID:17	0.067	Human
disease of anatomical entity	DOID:7	0.067	Human
disease of metabolism	DOID:0014667	0.050
nervous system disease	DOID:863	0.031
sensory system disease	DOID:0050155	0.024
eye and adnexa disease	DOID:1492	0.023
eye disease	DOID:5614	0.023
cardiovascular system disease	DOID:1287	0.019
intrinsic cardiomyopathy	DOID:0060036	0.017
cardiomyopathy	DOID:0050700	0.017
heart disease	DOID:114	0.017
nutrition disease	DOID:374	0.016
acquired metabolic disease	DOID:0060158	0.016
retinal disease	DOID:5679	0.013
inherited metabolic disorder	DOID:655	0.012
central nervous system disease	DOID:331	0.012

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