Rattus norvegicus

86 known processes

Ctsl1

cathepsin L1

(Aliases: Ctsl,CATHL)

Ctsl1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular catabolic processGO:00442482950.587
response to mechanical stimulusGO:00096121340.374
wound healingGO:00420601220.349
regulation of programmed cell deathGO:00430673410.344
response to other organismGO:00517072200.320
catabolic processGO:00090563510.320
response to peptideGO:19016522920.314
response to molecule of bacterial originGO:00022371940.281
regulation of molecular functionGO:00650093980.266
vesicle mediated transportGO:00161921810.264
multicellular organismal catabolic processGO:004424320.226
oxoacid metabolic processGO:00434362900.220
carboxylic acid metabolic processGO:00197522890.208
response to biotic stimulusGO:00096072260.206
single organism catabolic processGO:00447122830.203
programmed cell deathGO:00125013920.192
response to inorganic substanceGO:00100353770.188
regulation of catalytic activityGO:00507903040.187
organic substance catabolic processGO:19015753160.187
regulation of vesicle mediated transportGO:0060627810.181
blood coagulationGO:0007596260.173
tissue developmentGO:00098882520.172
regulation of ion transportGO:00432692450.170
neuron differentiationGO:00301823680.162
response to reactive oxygen speciesGO:00003021200.159
protein maturationGO:0051604680.159
Mouse
regulation of hemostasisGO:190004690.159
endocytosisGO:0006897840.157
regulation of apoptotic processGO:00429813350.154
positive regulation of transportGO:00510502450.151
response to external biotic stimulusGO:00432072210.151
carbohydrate derivative metabolic processGO:19011353460.143
lymphocyte activationGO:0046649430.138
response to cytokineGO:00340972150.138
regulation of cell motilityGO:20001451310.132
cell motilityGO:00488702020.129
macromolecule localizationGO:00330362520.123
regulation of protein metabolic processGO:00512462890.120
multicellular organismal homeostasisGO:0048871490.118
Rat
regulation of cellular component organizationGO:00511283680.117
Mouse
apoptotic processGO:00069153810.111
brain developmentGO:00074202470.111
locomotionGO:00400112370.110
response to woundingGO:00096112540.109
positive regulation of catalytic activityGO:00430851840.108
synaptic transmissionGO:00072682350.108
cellular response to alcoholGO:0097306870.108
cell type specific apoptotic processGO:00972851340.106
protein complex assemblyGO:00064612630.105
anatomical structure morphogenesisGO:00096532980.105
Mouse
cellular response to starvationGO:0009267270.104
regulation of vasculature developmentGO:1901342440.103
organic acid metabolic processGO:00060822920.100
axon developmentGO:0061564960.100
cell projection organizationGO:00300303020.095
regulation of rna biosynthetic processGO:20011413810.093
regulation of cellular protein metabolic processGO:00322682670.092
regulation of cell proliferationGO:00421273590.092
Mouse
response to hydrogen peroxideGO:0042542890.091
central nervous system developmentGO:00074173110.091
metal ion transportGO:00300012890.087
single organism intracellular transportGO:19025821660.087
cellular amine metabolic processGO:0044106380.085
neuron apoptotic processGO:0051402880.085
positive regulation of developmental processGO:00510942830.085
localization of cellGO:00516742020.084
sexual reproductionGO:00199531480.083
negative regulation of molecular functionGO:00440921330.082
positive regulation of multicellular organismal processGO:00512403870.081
head developmentGO:00603222470.079
cellular component movementGO:00069282480.078
regenerationGO:00310991630.078
single organism cellular localizationGO:19025801020.077
positive regulation of signalingGO:00230562700.076
homeostatic processGO:00425923310.076
Rat
coagulationGO:0050817280.074
multicellular organism reproductionGO:00325042330.074
negative regulation of programmed cell deathGO:00430691830.074
amine metabolic processGO:0009308380.073
neuron projection developmentGO:00311752730.073
blood vessel morphogenesisGO:0048514580.073
response to lipopolysaccharideGO:00324961910.072
cellular component biogenesisGO:00440853680.071
regulation of body fluid levelsGO:0050878900.071
developmental growthGO:00485891000.069
glycosyl compound catabolic processGO:19016581260.067
neuron projection morphogenesisGO:00488121220.066
regulation of signal transductionGO:00099663180.065
negative regulation of cell deathGO:00605482290.065
regulation of neuron differentiationGO:00456642080.064
membrane organizationGO:0061024940.063
negative regulation of response to woundingGO:1903035230.061
negative regulation of apoptotic processGO:00430661810.061
positive regulation of nervous system developmentGO:00519621780.060
autophagyGO:0006914190.060
positive regulation of molecular functionGO:00440932300.059
reproductive processGO:00224143720.059
cellular component assemblyGO:00226073600.059
glycosyl compound metabolic processGO:19016571820.059
single organism membrane organizationGO:0044802740.057
ribonucleoside triphosphate metabolic processGO:00091991410.057
cell projection morphogenesisGO:00488581230.056
positive regulation of response to stimulusGO:00485842850.056
regulation of wound healingGO:0061041140.056
regulation of locomotionGO:00400121480.055
single organism reproductive processGO:00447022970.054
regulation of immunoglobulin productionGO:000263740.053
positive regulation of cell communicationGO:00106472710.052
cellular response to endogenous stimulusGO:00714953770.052
cell activationGO:0001775970.052
response to oxidative stressGO:00069791860.052
angiogenesisGO:0001525530.052
cellular response to organic cyclic compoundGO:00714072020.051
receptor mediated endocytosisGO:0006898420.051
protein targetingGO:0006605610.051
protein localization to membraneGO:0072657360.051
macromolecular complex assemblyGO:00650032730.050
monovalent inorganic cation transportGO:00156721720.050
response to nutrient levelsGO:00316673700.049
purine containing compound catabolic processGO:00725231380.048
reproductive structure developmentGO:00486081280.048
tube developmentGO:0035295890.047
protein complex biogenesisGO:00702712630.046
growthGO:00400071650.046
epithelium developmentGO:0060429960.046
response to hypoxiaGO:00016662310.046
single fertilizationGO:000733830.046
cellular macromolecule localizationGO:00707271220.045
negative regulation of cell proliferationGO:00082851190.045
Mouse
regulation of cellular amine metabolic processGO:003323880.044
positive regulation of neuron differentiationGO:00456661260.044
response to peptide hormoneGO:00434342780.044
negative regulation of transportGO:00510511360.044
inorganic cation transmembrane transportGO:00986622020.044
monocarboxylic acid metabolic processGO:00327871520.043
protein processingGO:0016485680.042
Mouse
amide transportGO:00428861050.042
epithelial cell differentiationGO:0030855710.042
anatomical structure formation involved in morphogenesisGO:0048646830.042
response to bacteriumGO:00096172000.042
ion transmembrane transportGO:00342203650.041
immune effector processGO:0002252530.040
organic cyclic compound catabolic processGO:19013611750.040
gliogenesisGO:0042063930.040
neuron deathGO:00709971270.040
positive regulation of cell proliferationGO:00082842490.039
defense responseGO:00069521940.039
positive regulation of cell differentiationGO:00455972170.039
positive regulation of cell motilityGO:2000147970.039
regulation of response to woundingGO:1903034690.039
carbohydrate derivative catabolic processGO:19011361470.038
regulation of cell differentiationGO:00455953200.038
regulation of cellular localizationGO:00603412630.037
striated muscle tissue developmentGO:0014706580.037
chemical homeostasisGO:00488782920.037
transmembrane transportGO:00550854120.036
cell migrationGO:00164771970.036
cellular response to glucocorticoid stimulusGO:0071385680.036
regulation of hydrolase activityGO:00513361430.036
positive regulation of signal transductionGO:00099671750.036
nucleoside triphosphate metabolic processGO:00091411440.036
regulation of multicellular organismal developmentGO:20000263760.036
intracellular protein transportGO:0006886790.036
protein oligomerizationGO:00512591910.036
cellular amino acid metabolic processGO:00065201070.035
hemostasisGO:0007599260.035
fertilizationGO:000956630.035
regulation of neuron projection developmentGO:00109751610.035
proteolysisGO:00065081750.035
purine ribonucleotide catabolic processGO:00091541360.034
cellular ketone metabolic processGO:0042180510.034
ribonucleotide catabolic processGO:00092611360.034
regulation of immune responseGO:0050776550.034
negative regulation of multicellular organismal processGO:00512412030.034
regulation of cell developmentGO:00602842630.034
nucleotide metabolic processGO:00091172790.034
cellular protein localizationGO:00346131220.033
regulation of cellular component movementGO:00512701500.033
cation transportGO:00068123820.033
agingGO:00075682410.033
regulation of anatomical structure morphogenesisGO:00226031410.033
blood vessel developmentGO:0001568690.033
neuron developmentGO:00486662860.033
positive regulation of cellular component organizationGO:00511302000.033
positive regulation of nitrogen compound metabolic processGO:00511733340.032
regulation of phosphorylationGO:00423252480.032
nucleotide catabolic processGO:00091661390.032
peptidyl tyrosine modificationGO:0018212720.032
muscle tissue developmentGO:0060537580.032
negative regulation of metabolic processGO:00098923310.032
regulation of endocytosisGO:0030100420.032
cellular response to oxygen containing compoundGO:19017013860.032
organonitrogen compound catabolic processGO:19015651790.031
negative regulation of hemostasisGO:190004760.031
purine ribonucleotide metabolic processGO:00091502270.031
purine ribonucleoside triphosphate catabolic processGO:00092071220.031
intracellular transportGO:00469071850.031
cell junction organizationGO:0034330210.031
positive regulation of cell migrationGO:0030335960.030
negative regulation of macromolecule metabolic processGO:00106052600.030
response to estrogenGO:00436272320.030
epithelial cell migrationGO:0010631190.030
rubidium ion transportGO:003582610.029
regulation of intracellular signal transductionGO:19025312180.029
heterocycle catabolic processGO:00467001670.029
negative regulation of response to stimulusGO:00485851550.029
cellular response to external stimulusGO:00714961180.029
autophagic cell deathGO:004810240.028
positive regulation of programmed cell deathGO:00430681570.028
purine ribonucleoside catabolic processGO:00461301240.028
cell cell signalingGO:00072673350.028
nucleoside catabolic processGO:00091641260.028
receptor internalizationGO:0031623140.028
cellular response to growth factor stimulusGO:00713631620.028
purine nucleotide catabolic processGO:00061951360.027
rna metabolic processGO:00160704060.027
positive regulation of cellular amine metabolic processGO:003324030.027
positive regulation of phosphate metabolic processGO:00459372620.027
nucleoside phosphate catabolic processGO:19012921400.026
negative regulation of humoral immune responseGO:000292140.026
multicellular organismal reproductive processGO:00486092330.026
ribose phosphate metabolic processGO:00196932350.026
regulation of cellular ketone metabolic processGO:0010565270.026
intracellular signal transductionGO:00355563140.026
muscle structure developmentGO:0061061870.025
regulation of transcription dna templatedGO:00063553740.025
cellular response to nitrogen compoundGO:19016992100.025
negative regulation of endopeptidase activityGO:0010951360.025
regulation of immune system processGO:00026821230.025
positive regulation of cell developmentGO:00107201760.025
multi organism reproductive processGO:00447032620.025
muscle organ developmentGO:0007517500.025
ribonucleotide metabolic processGO:00092592310.025
response to glucoseGO:00097491360.024
regulation of secretionGO:00510462240.024
nucleobase containing compound catabolic processGO:00346551520.024
positive regulation of locomotionGO:00400171020.024
reproductionGO:00000032450.024
cellular divalent inorganic cation homeostasisGO:00725031620.024
regulation of rna metabolic processGO:00512523910.024
regulation of response to stressGO:00801341260.023
response to estradiolGO:00323551640.023
regulation of cellular amino acid metabolic processGO:000652120.023
immune system processGO:00023762040.023
macromolecular complex subunit organizationGO:00439333390.023
cellular protein catabolic processGO:0044257190.023
establishment of protein localizationGO:00451841410.023
cellular modified amino acid metabolic processGO:0006575610.023
axonogenesisGO:0007409710.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.022
multi multicellular organism processGO:00447061380.022
ameboidal type cell migrationGO:0001667260.022
cell adhesionGO:00071551100.022
aromatic compound catabolic processGO:00194391680.022
regulation of blood coagulationGO:003019390.022
purine nucleotide metabolic processGO:00061632290.022
nucleoside triphosphate catabolic processGO:00091431230.022
acute inflammatory responseGO:0002526580.022
cellular response to nutrient levelsGO:0031669600.021
protein phosphorylationGO:00064683450.021
regulation of epithelial cell migrationGO:0010632170.021
negative regulation of protein maturationGO:1903318470.021
respiratory system developmentGO:0060541450.021
secretionGO:00469033070.021
regulation of catabolic processGO:00098941130.021
single organism carbohydrate metabolic processGO:00447231180.021
purine nucleoside metabolic processGO:00422781690.021
response to extracellular stimulusGO:00099913800.021
dna conformation changeGO:0071103100.021
protein complex subunit organizationGO:00718223020.020
response to growth factorGO:00708481890.020
cellular response to stressGO:00335542690.020
cellular response to extracellular stimulusGO:0031668730.020
positive regulation of cell projection organizationGO:00313461110.020
protein transportGO:00150311320.020
collagen catabolic processGO:003057420.020
adult locomotory behaviorGO:000834440.020
transcription from rna polymerase ii promoterGO:00063662520.020
regulation of protein phosphorylationGO:00019321830.020
negative regulation of peptidase activityGO:0010466380.020
regulation of angiogenesisGO:0045765390.020
secretion by cellGO:00329402480.020
positive regulation of apoptotic processGO:00430651540.020
cellular homeostasisGO:00197252520.020
cellular response to organonitrogen compoundGO:00714171970.019
positive regulation of neurogenesisGO:00507691650.019
metal ion homeostasisGO:00550651860.019
regulation of nervous system developmentGO:00519602640.019
ribonucleoside triphosphate catabolic processGO:00092031220.019
cell part morphogenesisGO:00329901230.019
cellular response to oxidative stressGO:0034599760.019
regulation of protein modification processGO:00313991940.019
gtp catabolic processGO:0006184710.019
negative regulation of protein processingGO:0010955470.019
vasculature developmentGO:0001944700.019
negative regulation of immune responseGO:0050777150.019
monosaccharide metabolic processGO:0005996610.018
regulation of immune effector processGO:0002697320.018
response to monosaccharideGO:00342841590.018
negative regulation of response to external stimulusGO:0032102370.018
endosomal transportGO:0016197140.018
negative regulation of gene expressionGO:00106291990.018
cell cell junction organizationGO:0045216200.018
negative regulation of neutrophil apoptotic processGO:003303030.018
cellular response to hormone stimulusGO:00328702470.018
regulation of cell migrationGO:00303341280.018
cellular nitrogen compound catabolic processGO:00442701630.018
carboxylic acid transportGO:00469421150.018
protein localizationGO:00081041910.017
regulation of phagocytosisGO:0050764130.017
negative regulation of protein metabolic processGO:00512481140.017
inflammatory responseGO:00069541500.017
nucleoside phosphate metabolic processGO:00067532830.017
carbohydrate metabolic processGO:00059751300.017
regulation of defense responseGO:0031347680.017
cell junction assemblyGO:0034329180.017
negative regulation of signalingGO:00230571570.017
regulation of membrane potentialGO:00423911100.017
translationGO:0006412350.017
regulation of phosphate metabolic processGO:00192203490.016
response to axon injuryGO:0048678590.016
spermatogenesisGO:0007283990.016
circulatory system developmentGO:00723591340.016
regulation of leukocyte activationGO:0002694450.016
nerve developmentGO:0021675110.016
response to acid chemicalGO:00011012220.016
organic anion transportGO:00157111320.016
gamete generationGO:00072761240.016
gastrulationGO:000736920.016
cell morphogenesis involved in neuron differentiationGO:00486671060.016
nitrogen compound transportGO:00717052290.016
regulation of synaptic transmissionGO:00508041410.015
organophosphate catabolic processGO:00464341480.015
establishment of vesicle localizationGO:0051650310.015
regulation of cellular catabolic processGO:00313291010.015
divalent inorganic cation homeostasisGO:00725071650.015
cation homeostasisGO:00550801950.015
cellular component morphogenesisGO:00329891550.015
macroautophagyGO:001623640.015
neuromuscular synaptic transmissionGO:000727420.015
regulation of metal ion transportGO:00109591180.015
positive regulation of phosphorus metabolic processGO:00105622620.015
response to oxygen levelsGO:00704822650.015
cellular chemical homeostasisGO:00550822470.015
regulation of protein processingGO:0070613500.015
positive regulation of angiogenesisGO:0045766280.015
protein activation cascadeGO:0072376120.015
negative regulation of cell communicationGO:00106481580.015
regulation of response to external stimulusGO:00321011060.015
cytoplasmic transportGO:00164821150.014
cardiovascular system developmentGO:00723581340.014
calcium ion transportGO:00068161310.014
response to starvationGO:0042594590.014
male gamete generationGO:0048232990.014
regulation of protein maturationGO:1903317500.014
dna metabolic processGO:0006259960.014
positive regulation of neuron projection developmentGO:0010976990.014
vascular endothelial growth factor signaling pathwayGO:003808440.014
ribonucleoside catabolic processGO:00424541260.014
positive regulation of rna biosynthetic processGO:19026801970.014
cellular response to campGO:0071320260.014
cellular lipid metabolic processGO:00442552080.014
cellular response to hydrogen peroxideGO:0070301420.014
gland developmentGO:00487321550.014
purine nucleoside catabolic processGO:00061521240.014
macromolecule catabolic processGO:0009057580.013
mesodermal cell differentiationGO:004833310.013
cell substrate adhesionGO:0031589290.013
cell matrix adhesionGO:0007160190.013
regulation of phosphorus metabolic processGO:00511743490.013
reactive oxygen species metabolic processGO:0072593370.013
leukocyte activationGO:0045321760.013
response to glucocorticoidGO:00513842230.013
positive regulation of protein modification processGO:00314011420.013
response to decreased oxygen levelsGO:00362932370.012
dendrite developmentGO:0016358720.012
cellular response to reactive oxygen speciesGO:0034614550.012
signal releaseGO:00230611450.012
protein homooligomerizationGO:0051260910.012
receptor metabolic processGO:0043112180.012
sensory perceptionGO:00076001010.012
regulation of peptidase activityGO:0052547550.012
regulation of neuron deathGO:19012141150.012
cell chemotaxisGO:0060326310.012
regulation of protein transportGO:0051223680.012
response to campGO:0051591910.012
neurological system processGO:00508772190.012
regulation of cell activationGO:0050865500.012
gtp metabolic processGO:0046039720.012
positive regulation of cell junction assemblyGO:190189020.012
calcium ion homeostasisGO:00550741620.012
regulation of lymphocyte proliferationGO:0050670260.012
exocytosisGO:0006887600.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
regulation of leukocyte proliferationGO:0070663260.011
guanosine containing compound metabolic processGO:1901068740.011
positive regulation of immune system processGO:0002684900.011
sperm egg recognitionGO:003503610.011
positive regulation of gene expressionGO:00106282440.011
hexose metabolic processGO:0019318580.011
ribonucleoside metabolic processGO:00091191740.011
cellular response to vascular endothelial growth factor stimulusGO:003592460.011
purine ribonucleoside metabolic processGO:00461281680.011
positive regulation of catabolic processGO:0009896780.011
negative regulation of cellular metabolic processGO:00313242810.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
ion homeostasisGO:00508012120.011
anion transportGO:00068201780.011
rna biosynthetic processGO:00327743800.011
sensory perception of bitter tasteGO:005091340.011
regulation of calcium ion transportGO:0051924770.011
antigen processing and presentation of exogenous peptide antigen via mhc class iiGO:001988610.011
positive regulation of transcription dna templatedGO:00458931970.011
ras protein signal transductionGO:0007265290.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
cellular response to corticosteroid stimulusGO:0071384690.011
regulation of phospholipase activityGO:0010517120.010
cellular response to ketoneGO:1901655510.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
neuron projection regenerationGO:0031102350.010
activation of phospholipase d activityGO:003158420.010
regulation of receptor internalizationGO:000209060.010
regulation of anatomical structure sizeGO:00900661350.010
response to metal ionGO:00100382530.010
endothelium developmentGO:0003158120.010
response to hexoseGO:00097461440.010
cellular calcium ion homeostasisGO:00068741600.010
urogenital system developmentGO:0001655780.010
small gtpase mediated signal transductionGO:0007264360.010
negative regulation of proteolysisGO:0045861410.010
digestive tract developmentGO:0048565390.010
negative regulation of wound healingGO:006104580.010

Ctsl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.051
disease of anatomical entityDOID:700.051
musculoskeletal system diseaseDOID:1700.047
central nervous system diseaseDOID:33100.027
brain diseaseDOID:93600.015
epilepsy syndromeDOID:182600.015
electroclinical syndromeDOID:005070100.013