IMP: Integrative Multi-species Prediction

Rattus norvegicus

37 known processes

Egr2

early growth response 2

(Aliases: Krox20)

Entrez: 114090
Ensembl: ENSRNOG00000000640
RGD: 621608
UniProtKB: P51774

Process Predictions
Disease Predictions

Egr2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
skeletal muscle cell differentiation	GO:0035914	2	0.925	Mouse
glomerular mesangial cell proliferation	GO:0072110	4	0.876	Rat
positive regulation of neuron apoptotic process	GO:0043525	33	0.775	Rat
response to organophosphorus	GO:0046683	102	0.755	Rat
cell proliferation involved in kidney development	GO:0072111	5	0.744	Rat
cell motility	GO:0048870	202	0.744	Fly
cellular response to mycophenolic acid	GO:0071506	2	0.728	Rat
regulation of vasculature development	GO:1901342	44	0.661	Rat
positive regulation of metanephros development	GO:0072216	2	0.642	Rat
glomerular mesangium development	GO:0072109	4	0.619	Rat
response to purine containing compound	GO:0014074	126	0.603	Rat
cellular response to peptide hormone stimulus	GO:0071375	120	0.571	Rat
inactivation of mapk activity	GO:0000188	2	0.571
positive regulation of cell proliferation involved in kidney development	GO:1901724	4	0.564	Rat
response to hydrogen peroxide	GO:0042542	89	0.563
taxis	GO:0042330	67	0.563	Mouse
skeletal system development	GO:0001501	41	0.557
response to amphetamine	GO:0001975	25	0.557	Rat
cellular response to endogenous stimulus	GO:0071495	377	0.555	Rat
cell proliferation involved in metanephros development	GO:0072203	2	0.544	Rat
tissue development	GO:0009888	252	0.544	Mouse Rat Fly
embryonic skeletal system development	GO:0048706	3	0.541
aging	GO:0007568	241	0.534
cellular response to isoquinoline alkaloid	GO:0071317	6	0.521	Rat
rhythmic process	GO:0048511	156	0.519	Mouse Rat
response to ketone	GO:1901654	182	0.495
regulation of apoptotic process	GO:0042981	335	0.490	Rat
programmed cell death	GO:0012501	392	0.484	Rat
anatomical structure morphogenesis	GO:0009653	298	0.480	Zebrafish Mouse Fly
cellular response to interleukin 1	GO:0071347	37	0.475
response to peptide hormone	GO:0043434	278	0.468
metanephric glomerulus vasculature development	GO:0072239	1	0.465	Rat
positive regulation of multicellular organismal process	GO:0051240	387	0.463	Rat
kidney vasculature development	GO:0061440	6	0.455	Rat
cellular response to drug	GO:0035690	30	0.454	Rat
cellular response to lipid	GO:0071396	201	0.449	Rat
learning or memory	GO:0007611	90	0.445
positive regulation of cell migration	GO:0030335	96	0.444
bmp signaling pathway	GO:0030509	4	0.439
response to corticosteroid	GO:0031960	235	0.439
angiogenesis	GO:0001525	53	0.437
behavior	GO:0007610	205	0.432
cellular response to alkaloid	GO:0071312	25	0.428	Rat
collateral sprouting	GO:0048668	2	0.405
response to interleukin 1	GO:0070555	55	0.402
response to insulin	GO:0032868	133	0.397
positive regulation of cell proliferation	GO:0008284	249	0.384	Rat
cellular response to gonadotropin stimulus	GO:0071371	17	0.384	Rat
response to amine	GO:0014075	46	0.378	Rat
positive regulation of apoptotic process	GO:0043065	154	0.366	Rat
response to camp	GO:0051591	91	0.362	Rat
positive regulation of programmed cell death	GO:0043068	157	0.359	Rat
response to wounding	GO:0009611	254	0.353
regulation of programmed cell death	GO:0043067	341	0.351	Rat
cellular response to organic cyclic compound	GO:0071407	202	0.345	Rat
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.344
rna metabolic process	GO:0016070	406	0.342	Mouse Rat
regulation of protein metabolic process	GO:0051246	289	0.341
long term synaptic potentiation	GO:0060291	21	0.334	Rat
regulation of glomerular mesangial cell proliferation	GO:0072124	4	0.333	Rat
regulation of cell proliferation	GO:0042127	359	0.325	Rat
conditioned taste aversion	GO:0001661	2	0.320
response to alkaloid	GO:0043279	132	0.320	Rat
cardiovascular system development	GO:0072358	134	0.317	Rat
positive regulation of g0 to g1 transition	GO:0070318	2	0.311
immune system process	GO:0002376	204	0.309
response to mechanical stimulus	GO:0009612	134	0.309	Rat
cellular response to insulin stimulus	GO:0032869	81	0.305	Rat
response to gamma radiation	GO:0010332	24	0.305
glomerulus development	GO:0032835	10	0.304	Rat
positive regulation of glomerulus development	GO:0090193	4	0.293	Rat
regulation of metanephric glomerulus development	GO:0072298	1	0.292	Rat
regulation of multicellular organismal development	GO:2000026	376	0.290	Rat
positive regulation of glomerular mesangial cell proliferation	GO:0072126	4	0.286	Rat
cellular response to cytokine stimulus	GO:0071345	127	0.285
skeletal muscle tissue development	GO:0007519	31	0.285	Mouse
response to peptide	GO:1901652	292	0.285
multi multicellular organism process	GO:0044706	138	0.274
circulatory system development	GO:0072359	134	0.269	Rat
regulation of canonical wnt signaling pathway	GO:0060828	4	0.268
regulation of cellular protein metabolic process	GO:0032268	267	0.264
regulation of nucleic acid templated transcription	GO:1903506	380	0.264	Human Mouse Rat
nucleic acid templated transcription	GO:0097659	379	0.261	Mouse Rat
response to acid chemical	GO:0001101	222	0.260	Rat
positive regulation of cell death	GO:0010942	184	0.259	Rat
interleukin 1 mediated signaling pathway	GO:0070498	2	0.256
response to ammonium ion	GO:0060359	71	0.254	Rat
response to hyperoxia	GO:0055093	45	0.251	Rat
response to follicle stimulating hormone	GO:0032354	18	0.246	Rat
response to light stimulus	GO:0009416	52	0.240
circadian rhythm	GO:0007623	88	0.240	Rat
positive regulation of synaptic transmission	GO:0050806	62	0.239	Rat
negative regulation of cellular biosynthetic process	GO:0031327	161	0.238
response to decreased oxygen levels	GO:0036293	237	0.236	Rat
neuron differentiation	GO:0030182	368	0.236	Mouse
response to radiation	GO:0009314	137	0.235
positive regulation of developmental process	GO:0051094	283	0.226	Rat
response to increased oxygen levels	GO:0036296	45	0.226	Rat
cellular component biogenesis	GO:0044085	368	0.223
positive regulation of cell motility	GO:2000147	97	0.221
cellular component morphogenesis	GO:0032989	155	0.221	Zebrafish Mouse
cellular component assembly	GO:0022607	360	0.220
metanephric glomerular mesangial cell proliferation involved in metanephros development	GO:0072262	1	0.219	Rat
response to catecholamine	GO:0071869	16	0.218	Rat
cellular component movement	GO:0006928	248	0.216	Mouse Fly
regulation of metanephros development	GO:0072215	4	0.213	Rat
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.211
apoptotic process	GO:0006915	381	0.209	Rat
response to inorganic substance	GO:0010035	377	0.209
regulation of system process	GO:0044057	208	0.208
response to glucocorticoid	GO:0051384	223	0.203
connective tissue development	GO:0061448	33	0.203	Rat
transcription dna templated	GO:0006351	377	0.200	Mouse Rat
metanephric glomerular mesangium development	GO:0072223	1	0.199	Rat
cytokine mediated signaling pathway	GO:0019221	43	0.199
response to oxidative stress	GO:0006979	186	0.197
gliogenesis	GO:0042063	93	0.196	Zebrafish Mouse Rat
response to isoquinoline alkaloid	GO:0014072	28	0.195	Rat
regulation of rna metabolic process	GO:0051252	391	0.191	Human Mouse Rat
neuron apoptotic process	GO:0051402	88	0.191	Rat
neuron projection development	GO:0031175	273	0.190	Mouse
myeloid leukocyte migration	GO:0097529	20	0.188
positive regulation of biosynthetic process	GO:0009891	319	0.187	Mouse Rat
cognition	GO:0050890	92	0.184
response to heparin	GO:0071503	2	0.182	Rat
response to extracellular stimulus	GO:0009991	380	0.181	Rat
regulation of cell motility	GO:2000145	131	0.177
negative regulation of cellular metabolic process	GO:0031324	281	0.175
response to toxic substance	GO:0009636	133	0.175	Rat
positive regulation of cellular biosynthetic process	GO:0031328	295	0.174	Mouse Rat
regulation of neuron apoptotic process	GO:0043523	83	0.174	Rat
regulation of rna biosynthetic process	GO:2001141	381	0.172	Human Mouse Rat
synaptic growth at neuromuscular junction	GO:0051124	1	0.171
single organism behavior	GO:0044708	130	0.170
positive regulation of cellular component movement	GO:0051272	102	0.167
negative regulation of metabolic process	GO:0009892	331	0.166
response to growth factor	GO:0070848	189	0.165	Rat
response to metal ion	GO:0010038	253	0.164
regulation of neuronal synaptic plasticity	GO:0048168	31	0.164
negative regulation of programmed cell death	GO:0043069	183	0.164
regulation of cellular component movement	GO:0051270	150	0.162
response to oxygen levels	GO:0070482	265	0.160	Rat
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.156	Zebrafish Mouse
response to monoamine	GO:0071867	17	0.156	Rat
regulation of transcription dna templated	GO:0006355	374	0.155	Human Mouse Rat
axon development	GO:0061564	96	0.154	Mouse
striated muscle tissue development	GO:0014706	58	0.154	Mouse
endocytosis	GO:0006897	84	0.150	Fly
locomotion	GO:0040011	237	0.148	Mouse Fly
epithelial cell migration	GO:0010631	19	0.147	Fly
response to axon injury	GO:0048678	59	0.147
female pregnancy	GO:0007565	122	0.146
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.146	Mouse Rat
transcription from rna polymerase ii promoter	GO:0006366	252	0.145	Mouse Rat
neuron death	GO:0070997	127	0.145	Rat
protein sumoylation	GO:0016925	4	0.145
cell cell signaling	GO:0007267	335	0.144
muscle tissue development	GO:0060537	58	0.143	Mouse
vasculature development	GO:0001944	70	0.142	Rat
neuron projection morphogenesis	GO:0048812	122	0.140	Mouse
cellular response to steroid hormone stimulus	GO:0071383	93	0.140	Rat
negative regulation of rna metabolic process	GO:0051253	123	0.140
metanephric glomerulus development	GO:0072224	3	0.139	Rat
regulation of neuron death	GO:1901214	115	0.139	Rat
central nervous system development	GO:0007417	311	0.138	Zebrafish Mouse Rat Fly
cellular response to oxygen containing compound	GO:1901701	386	0.136	Rat
negative regulation of macromolecule metabolic process	GO:0010605	260	0.135
regulation of protein modification process	GO:0031399	194	0.130
regulation of osteoclast differentiation	GO:0045670	8	0.130
cellular response to external stimulus	GO:0071496	118	0.127	Rat
kidney development	GO:0001822	67	0.127	Rat
embryonic skeletal system morphogenesis	GO:0048704	3	0.126
wound healing	GO:0042060	122	0.126
regulation of signal transduction	GO:0009966	318	0.125
growth	GO:0040007	165	0.124
blood circulation	GO:0008015	183	0.123
single organism reproductive process	GO:0044702	297	0.122
positive regulation of signaling	GO:0023056	270	0.120	Rat
neurological system process	GO:0050877	219	0.118
positive regulation of cell differentiation	GO:0045597	217	0.117
sensory organ development	GO:0007423	74	0.116
cellular response to fluid shear stress	GO:0071498	4	0.116
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.116	Mouse Rat
response to cocaine	GO:0042220	39	0.116	Rat
negative regulation of response to stimulus	GO:0048585	155	0.115
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.115	Mouse Rat
hindlimb morphogenesis	GO:0035137	2	0.114
regulation of molecular function	GO:0065009	398	0.111
response to antibiotic	GO:0046677	39	0.111	Rat
chemotaxis	GO:0006935	66	0.110	Mouse
cell projection organization	GO:0030030	302	0.110	Mouse
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.110	Mouse Rat
negative regulation of multicellular organismal process	GO:0051241	203	0.110
regulation of myeloid cell differentiation	GO:0045637	12	0.109
negative regulation of cellular protein metabolic process	GO:0032269	106	0.107
cell migration	GO:0016477	197	0.106	Fly
glial cell differentiation	GO:0010001	65	0.105	Zebrafish Mouse Rat
regulation of cell migration	GO:0030334	128	0.104
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.104
positive regulation of cell communication	GO:0010647	271	0.104	Rat
limb morphogenesis	GO:0035108	4	0.104
response to glucose	GO:0009749	136	0.104
regulation of cell adhesion	GO:0030155	52	0.103
axonogenesis	GO:0007409	71	0.102	Mouse
response to bacterium	GO:0009617	200	0.102
cellular response to growth factor stimulus	GO:0071363	162	0.102	Rat
eye development	GO:0001654	50	0.101
negative regulation of canonical wnt signaling pathway	GO:0090090	4	0.099
glomerulus vasculature development	GO:0072012	6	0.098	Rat
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	75	0.096
response to carbohydrate	GO:0009743	183	0.093
leukocyte differentiation	GO:0002521	30	0.092
locomotor rhythm	GO:0045475	1	0.091
response to norepinephrine	GO:0071873	5	0.091	Rat
single organism biosynthetic process	GO:0044711	342	0.090
response to cytokine	GO:0034097	215	0.090
positive regulation of gene expression	GO:0010628	244	0.090	Mouse Rat
regulation of nervous system development	GO:0051960	264	0.089
positive regulation of rna biosynthetic process	GO:1902680	197	0.088	Mouse Rat
cellular response to peptide	GO:1901653	133	0.087	Rat
cell chemotaxis	GO:0060326	31	0.087
rhythmic behavior	GO:0007622	24	0.086	Mouse
regulation of locomotion	GO:0040012	148	0.085
skeletal muscle organ development	GO:0060538	33	0.084	Mouse
negative regulation of cell death	GO:0060548	229	0.084
regulation of cell development	GO:0060284	263	0.084
protein dephosphorylation	GO:0006470	38	0.084
response to indole 3 methanol	GO:0071680	2	0.084
negative regulation of cell communication	GO:0010648	158	0.082
localization of cell	GO:0051674	202	0.082	Fly
osteoclast differentiation	GO:0030316	11	0.081
cellular response to hormone stimulus	GO:0032870	247	0.081	Rat
developmental growth	GO:0048589	100	0.080
organ regeneration	GO:0031100	101	0.079
response to ionizing radiation	GO:0010212	59	0.079
response to temperature stimulus	GO:0009266	94	0.078
response to biotic stimulus	GO:0009607	226	0.077
response to reactive oxygen species	GO:0000302	120	0.076
cellular response to nitrogen compound	GO:1901699	210	0.076	Rat
wound healing spreading of cells	GO:0044319	2	0.075
negative regulation of signal transduction	GO:0009968	83	0.074
positive regulation of cellular catabolic process	GO:0031331	71	0.074
response to monosaccharide	GO:0034284	159	0.073
secretion by cell	GO:0032940	248	0.072
positive regulation of locomotion	GO:0040017	102	0.071
embryo development	GO:0009790	49	0.071	Fly
muscle structure development	GO:0061061	87	0.070	Mouse Fly
regulation of phosphorus metabolic process	GO:0051174	349	0.070
rna biosynthetic process	GO:0032774	380	0.070	Mouse Rat
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.069
circulatory system process	GO:0003013	183	0.068
protein phosphorylation	GO:0006468	345	0.068
regulation of immune system process	GO:0002682	123	0.066
negative regulation of gene expression	GO:0010629	199	0.066
axon regeneration	GO:0031103	28	0.065
cell type specific apoptotic process	GO:0097285	134	0.065	Rat
negative regulation of neuron apoptotic process	GO:0043524	45	0.065
regulation of kidney development	GO:0090183	15	0.064	Rat
response to mineralocorticoid	GO:0051385	49	0.063
regulation of catalytic activity	GO:0050790	304	0.063
response to ethanol	GO:0045471	162	0.063	Rat
regulation of long term neuronal synaptic plasticity	GO:0048169	15	0.062	Rat
cellular response to iron iii ion	GO:0071283	3	0.062
cellular response to transforming growth factor beta stimulus	GO:0071560	41	0.061
response to electrical stimulus	GO:0051602	56	0.060	Rat
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.060	Mouse Rat
vesicle mediated transport	GO:0016192	181	0.060	Fly
regulation of leukocyte migration	GO:0002685	24	0.060
cell cycle	GO:0007049	101	0.059
response to alkyl hydroperoxide	GO:0033195	1	0.058
regulation of phosphate metabolic process	GO:0019220	349	0.058
cellular response to acid chemical	GO:0071229	75	0.058	Rat
regulation of cell differentiation	GO:0045595	320	0.058
response to hypoxia	GO:0001666	231	0.058	Rat
cellular response to abiotic stimulus	GO:0071214	85	0.058	Rat
metanephric nephron development	GO:0072210	7	0.057	Rat
response to tumor necrosis factor	GO:0034612	56	0.056
regeneration	GO:0031099	163	0.056
cell morphogenesis involved in differentiation	GO:0000904	119	0.056	Zebrafish Mouse
neuron projection regeneration	GO:0031102	35	0.056
cell morphogenesis	GO:0000902	142	0.056	Zebrafish Mouse
cellular response to mechanical stimulus	GO:0071260	48	0.055	Rat
negative regulation of apoptotic process	GO:0043066	181	0.055
dna metabolic process	GO:0006259	96	0.055
heart contraction	GO:0060047	57	0.055
response to nutrient levels	GO:0031667	370	0.055	Rat
leukocyte migration	GO:0050900	38	0.054
cell growth	GO:0016049	104	0.054
cell part morphogenesis	GO:0032990	123	0.054	Mouse
cellular response to low density lipoprotein particle stimulus	GO:0071404	3	0.053
cellular response to camp	GO:0071320	26	0.053	Rat
regulation of neurogenesis	GO:0050767	247	0.053
negative regulation of cell proliferation	GO:0008285	119	0.052
response to corticosterone	GO:0051412	40	0.051
negative regulation of biosynthetic process	GO:0009890	168	0.051
response to low density lipoprotein particle	GO:0055098	4	0.051
cell activation	GO:0001775	97	0.050
regulation of myeloid leukocyte differentiation	GO:0002761	12	0.049
positive regulation of epithelial cell proliferation	GO:0050679	32	0.049
regulation of t cell migration	GO:2000404	1	0.048
heart process	GO:0003015	57	0.048
cellular response to stress	GO:0033554	269	0.048	Rat
reproduction	GO:0000003	245	0.047
regulation of protein phosphorylation	GO:0001932	183	0.047
response to lipopolysaccharide	GO:0032496	191	0.047
g2 m transition of mitotic cell cycle	GO:0000086	6	0.046
cellular response to tumor necrosis factor	GO:0071356	46	0.046
negative regulation of rna biosynthetic process	GO:1902679	118	0.046
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	27	0.045
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.045
neuron development	GO:0048666	286	0.045	Mouse
synaptic transmission	GO:0007268	235	0.045
multicellular organismal reproductive process	GO:0048609	233	0.044
muscle organ development	GO:0007517	50	0.044	Mouse Fly
ossification	GO:0001503	70	0.043	Mouse
mesoderm development	GO:0007498	2	0.043
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.043
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.043
muscle system process	GO:0003012	115	0.042
regulation of neuron projection development	GO:0010975	161	0.042
cell projection morphogenesis	GO:0048858	123	0.042	Mouse
response to external biotic stimulus	GO:0043207	221	0.042
negative regulation of signaling	GO:0023057	157	0.042
epiboly involved in wound healing	GO:0090505	2	0.041
response to amino acid	GO:0043200	75	0.041
feeding behavior	GO:0007631	53	0.040
cellular lipid metabolic process	GO:0044255	208	0.040
response to fibroblast growth factor	GO:0071774	29	0.040
regulation of cell projection organization	GO:0031344	175	0.040
cellular response to oxidative stress	GO:0034599	76	0.039
regulation of anatomical structure morphogenesis	GO:0022603	141	0.039
vascular process in circulatory system	GO:0003018	96	0.039
g protein coupled receptor signaling pathway	GO:0007186	242	0.038
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.038	Mouse Rat
response to cold	GO:0009409	29	0.038
regulation of synaptic transmission	GO:0050804	141	0.038
positive regulation of immune system process	GO:0002684	90	0.038
response to mycophenolic acid	GO:0071505	2	0.038	Rat
positive regulation of transcription dna templated	GO:0045893	197	0.037	Mouse Rat
regulation of cell proliferation involved in kidney development	GO:1901722	4	0.037	Rat
homeostatic process	GO:0042592	331	0.037
intracellular signal transduction	GO:0035556	314	0.036
multi organism reproductive process	GO:0044703	262	0.036
response to high light intensity	GO:0009644	1	0.036
developmental process involved in reproduction	GO:0003006	159	0.036
positive regulation of myeloid leukocyte differentiation	GO:0002763	7	0.035
carbohydrate derivative metabolic process	GO:1901135	346	0.035
transformation of host cell by virus	GO:0019087	4	0.035
regulation of erk1 and erk2 cascade	GO:0070372	41	0.035
gastrulation	GO:0007369	2	0.035
cellular response to ketone	GO:1901655	51	0.035
response to estrogen	GO:0043627	232	0.035
ion homeostasis	GO:0050801	212	0.034
negative regulation of phosphate metabolic process	GO:0045936	80	0.034
formation of primary germ layer	GO:0001704	1	0.034
embryonic hindlimb morphogenesis	GO:0035116	2	0.034
reproductive process	GO:0022414	372	0.034
response to vitamin d	GO:0033280	34	0.033
positive regulation of myeloid cell differentiation	GO:0045639	7	0.033
positive regulation of neuron death	GO:1901216	43	0.033	Rat
negative regulation of transcription dna templated	GO:0045892	116	0.033
cellular homeostasis	GO:0019725	252	0.033
gamete generation	GO:0007276	124	0.033
t helper 1 cell extravasation	GO:0035687	1	0.033
regulation of tube size	GO:0035150	89	0.032
regulation of lymphocyte chemotaxis	GO:1901623	1	0.032
negative regulation of neuron death	GO:1901215	69	0.032
negative regulation of oligodendrocyte differentiation	GO:0048715	3	0.031
cellular response to cycloheximide	GO:0071409	4	0.031
response to molecule of bacterial origin	GO:0002237	194	0.031
cellular response to biotic stimulus	GO:0071216	59	0.031
macromolecule localization	GO:0033036	252	0.031	Mouse
positive regulation of cell development	GO:0010720	176	0.031
appendage morphogenesis	GO:0035107	4	0.030
cytoskeleton organization	GO:0007010	111	0.030
lipid metabolic process	GO:0006629	283	0.030
regulation of protein kinase activity	GO:0045859	105	0.030
regulation of cell cycle	GO:0051726	73	0.030
regulation of lymphocyte migration	GO:2000401	1	0.029
reproductive system development	GO:0061458	128	0.029
response to calcium ion	GO:0051592	59	0.029
head development	GO:0060322	247	0.029	Zebrafish Mouse
organelle organization	GO:0006996	266	0.029
negative regulation of catalytic activity	GO:0043086	103	0.029
cellular response to organonitrogen compound	GO:0071417	197	0.029	Rat
carbohydrate biosynthetic process	GO:0016051	42	0.029
sexual reproduction	GO:0019953	148	0.028
cardiac muscle contraction	GO:0060048	27	0.028
phagocytosis	GO:0006909	17	0.028	Fly
cellular catabolic process	GO:0044248	295	0.028
secretion	GO:0046903	307	0.028
leukocyte activation	GO:0045321	76	0.028
single organism catabolic process	GO:0044712	283	0.028
positive regulation of molecular function	GO:0044093	230	0.028
sodium ion transport	GO:0006814	82	0.028
embryonic appendage morphogenesis	GO:0035113	4	0.028
brain development	GO:0007420	247	0.028	Zebrafish Mouse
cellular response to extracellular stimulus	GO:0031668	73	0.028
erk1 and erk2 cascade	GO:0070371	48	0.028
regulation of angiogenesis	GO:0045765	39	0.027
urogenital system development	GO:0001655	78	0.027	Rat
regulation of bmp signaling pathway	GO:0030510	2	0.027
response to insecticide	GO:0017085	21	0.027
positive regulation of saliva secretion	GO:0046878	3	0.027
response to progesterone	GO:0032570	48	0.027
cellular response to high density lipoprotein particle stimulus	GO:0071403	2	0.027
positive regulation of rna metabolic process	GO:0051254	203	0.027	Mouse Rat
embryo implantation	GO:0007566	15	0.027
response to hexose	GO:0009746	144	0.027
circadian behavior	GO:0048512	24	0.027
hematopoietic or lymphoid organ development	GO:0048534	36	0.027
dephosphorylation	GO:0016311	98	0.027
organonitrogen compound catabolic process	GO:1901565	179	0.027
mrna 3 end processing	GO:0031124	1	0.026
protein complex assembly	GO:0006461	263	0.026
regulation of cellular component organization	GO:0051128	368	0.026
cation transport	GO:0006812	382	0.026
cellular ion homeostasis	GO:0006873	184	0.026
organophosphate metabolic process	GO:0019637	370	0.026
cellular response to nutrient levels	GO:0031669	60	0.026
gland development	GO:0048732	155	0.026
negative regulation of nervous system development	GO:0051961	79	0.026
blood vessel morphogenesis	GO:0048514	58	0.026
cellular ketone metabolic process	GO:0042180	51	0.026
multicellular organism reproduction	GO:0032504	233	0.026
negative regulation of protein metabolic process	GO:0051248	114	0.026
regulation of intracellular signal transduction	GO:1902531	218	0.026
positive regulation of leukocyte migration	GO:0002687	21	0.026
lymphocyte chemotaxis	GO:0048247	3	0.026
positive regulation of osteoclast differentiation	GO:0045672	5	0.025
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.025	Mouse
divalent inorganic cation homeostasis	GO:0072507	165	0.025
regulation of synaptic plasticity	GO:0048167	70	0.025
response to vitamin	GO:0033273	131	0.025
organ formation	GO:0048645	3	0.025
negative regulation of wnt signaling pathway	GO:0030178	7	0.025
negative regulation of transferase activity	GO:0051348	29	0.025
regulation of transferase activity	GO:0051338	123	0.025
t cell differentiation	GO:0030217	9	0.025
positive regulation of response to stimulus	GO:0048584	285	0.024
smooth muscle cell migration	GO:0014909	36	0.024
positive regulation of synaptic plasticity	GO:0031915	3	0.024
muscle contraction	GO:0006936	88	0.024
regulation of g0 to g1 transition	GO:0070316	3	0.024
positive regulation of neurogenesis	GO:0050769	165	0.024
regulation of cellular ketone metabolic process	GO:0010565	27	0.024
cellular metal ion homeostasis	GO:0006875	172	0.024
single organism organelle organization	GO:1902589	180	0.024
chemical homeostasis	GO:0048878	292	0.024
cytokine biosynthetic process	GO:0042089	3	0.024
central nervous system neuron axonogenesis	GO:0021955	1	0.024
mast cell migration	GO:0097531	4	0.024
organ morphogenesis	GO:0009887	75	0.024
reproductive structure development	GO:0048608	128	0.024
dendrite morphogenesis	GO:0048813	43	0.023
salivary gland development	GO:0007431	3	0.023
cell cycle phase transition	GO:0044770	21	0.023
protein complex biogenesis	GO:0070271	263	0.023
hemopoiesis	GO:0030097	34	0.023
positive regulation of the force of heart contraction by norepinephrine	GO:0003061	1	0.023
transforming growth factor beta receptor signaling pathway	GO:0007179	18	0.023
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure	GO:0001999	1	0.023
positive regulation of cellular protein metabolic process	GO:0032270	167	0.023
oxoacid metabolic process	GO:0043436	290	0.023
response to nutrient	GO:0007584	248	0.023
biological adhesion	GO:0022610	110	0.023
regulation of smooth muscle cell proliferation	GO:0048660	75	0.022
small gtpase mediated signal transduction	GO:0007264	36	0.022
negative regulation of phosphorus metabolic process	GO:0010563	80	0.022
cellular response to corticosteroid stimulus	GO:0071384	69	0.022
immune system development	GO:0002520	41	0.022
single organism carbohydrate metabolic process	GO:0044723	118	0.022
regulation of phosphorylation	GO:0042325	248	0.022
prostate gland epithelium morphogenesis	GO:0060740	2	0.022
negative regulation of angiogenesis	GO:0016525	10	0.022
multicellular organismal macromolecule metabolic process	GO:0044259	21	0.021
carbohydrate derivative biosynthetic process	GO:1901137	124	0.021
negative regulation of mapk cascade	GO:0043409	20	0.021
regulation of blood circulation	GO:1903522	110	0.021
regulation of interleukin 1 alpha biosynthetic process	GO:0050721	1	0.021
positive regulation of neuron differentiation	GO:0045666	126	0.021
positive regulation of keratinocyte migration	GO:0051549	2	0.021
multicellular organismal catabolic process	GO:0044243	2	0.021
associative learning	GO:0008306	19	0.021
inner ear morphogenesis	GO:0042472	1	0.021
response to gravity	GO:0009629	13	0.021
regulation of neuron differentiation	GO:0045664	208	0.020
response to vitamin k	GO:0032571	4	0.020
amine metabolic process	GO:0009308	38	0.020
macromolecular complex assembly	GO:0065003	273	0.020
metal ion homeostasis	GO:0055065	186	0.020
myeloid leukocyte differentiation	GO:0002573	20	0.020
collagen metabolic process	GO:0032963	21	0.020
response to high density lipoprotein particle	GO:0055099	2	0.020
lipid biosynthetic process	GO:0008610	128	0.020
response to estradiol	GO:0032355	164	0.020
regulation of kinase activity	GO:0043549	117	0.020
cell adhesion	GO:0007155	110	0.020
neuromuscular process	GO:0050905	2	0.020
positive regulation of lymphocyte migration	GO:2000403	1	0.020

Egr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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