IMP: Integrative Multi-species Prediction

Rattus norvegicus

119 known processes

Gnai2

guanine nucleotide binding protein (G protein), alpha inhibiting 2

(Aliases: Galphai2)

RGD: 620243
Ensembl: ENSRNOG00000016592
Entrez: 81664
UniProtKB: Q45QN0
UniProtKB: P04897

Process Predictions
Disease Predictions

Gnai2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of mitochondrion organization	GO:0010821	7	0.401
regulation of programmed cell death	GO:0043067	341	0.330	Rat
cell cell signaling	GO:0007267	335	0.330
response to nutrient	GO:0007584	248	0.320
response to inorganic substance	GO:0010035	377	0.287	Rat
negative regulation of signaling	GO:0023057	157	0.257
embryonic cranial skeleton morphogenesis	GO:0048701	2	0.254
negative regulation of response to stimulus	GO:0048585	155	0.219
intracellular transport	GO:0046907	185	0.208	Yeast
anatomical structure morphogenesis	GO:0009653	298	0.197
response to cytokine	GO:0034097	215	0.185	Rat
apoptotic process	GO:0006915	381	0.184	Rat
programmed cell death	GO:0012501	392	0.165	Rat
carboxylic acid metabolic process	GO:0019752	289	0.158
regulation of cellular component movement	GO:0051270	150	0.157
cell motility	GO:0048870	202	0.153
cellular ketone metabolic process	GO:0042180	51	0.144
negative regulation of cell death	GO:0060548	229	0.140	Rat
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.140	Rat
response to growth factor	GO:0070848	189	0.139
rhythmic process	GO:0048511	156	0.138
cellular component movement	GO:0006928	248	0.137	Yeast
response to other organism	GO:0051707	220	0.133
response to extracellular stimulus	GO:0009991	380	0.129
regulation of immunoglobulin production	GO:0002637	4	0.129
organ morphogenesis	GO:0009887	75	0.127
response to estrogen	GO:0043627	232	0.127
response to lipopolysaccharide	GO:0032496	191	0.123
regulation of signal transduction	GO:0009966	318	0.121
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.118
t cell homeostasis	GO:0043029	2	0.114
response to metal ion	GO:0010038	253	0.114
response to molecule of bacterial origin	GO:0002237	194	0.113
response to peptide hormone	GO:0043434	278	0.111
positive regulation of phosphate metabolic process	GO:0045937	262	0.111
localization of cell	GO:0051674	202	0.111
positive regulation of cell migration	GO:0030335	96	0.110
response to ethanol	GO:0045471	162	0.109
positive regulation of response to stimulus	GO:0048584	285	0.108
response to nutrient levels	GO:0031667	370	0.108
cellular response to organonitrogen compound	GO:0071417	197	0.105
positive regulation of signaling	GO:0023056	270	0.103
reproduction	GO:0000003	245	0.103	Yeast
positive regulation of developmental process	GO:0051094	283	0.098
regulation of cell morphogenesis	GO:0022604	77	0.098
regulation of cellular amino acid metabolic process	GO:0006521	2	0.098
positive regulation of immunoglobulin mediated immune response	GO:0002891	2	0.097
cellular response to endogenous stimulus	GO:0071495	377	0.097
membrane organization	GO:0061024	94	0.096	Rat
cellular amino acid metabolic process	GO:0006520	107	0.096
oxoacid metabolic process	GO:0043436	290	0.096
regulation of locomotion	GO:0040012	148	0.095
macromolecular complex assembly	GO:0065003	273	0.094
positive regulation of multicellular organismal process	GO:0051240	387	0.094
regulation of cell motility	GO:2000145	131	0.094
response to peptide	GO:1901652	292	0.094
regulation of cell development	GO:0060284	263	0.093
amine metabolic process	GO:0009308	38	0.090
regulation of rna metabolic process	GO:0051252	391	0.090
negative regulation of cellular component organization	GO:0051129	83	0.089
response to hypoxia	GO:0001666	231	0.089
positive regulation of biosynthetic process	GO:0009891	319	0.088
reproductive system development	GO:0061458	128	0.088
response to carbohydrate	GO:0009743	183	0.087
response to bacterium	GO:0009617	200	0.085
behavior	GO:0007610	205	0.085
rna biosynthetic process	GO:0032774	380	0.084
liver development	GO:0001889	90	0.084
negative regulation of calcium ion transport into cytosol	GO:0010523	4	0.084
positive regulation of cell differentiation	GO:0045597	217	0.083
negative regulation of gene expression	GO:0010629	199	0.079
regulation of molecular function	GO:0065009	398	0.079
response to cadmium ion	GO:0046686	35	0.078
cellular response to growth factor stimulus	GO:0071363	162	0.076
cellular response to hormone stimulus	GO:0032870	247	0.076
regulation of anatomical structure morphogenesis	GO:0022603	141	0.076
positive regulation of endothelial cell migration	GO:0010595	4	0.074
multicellular organism reproduction	GO:0032504	233	0.074
purine ribonucleotide biosynthetic process	GO:0009152	81	0.073
cellular response to organic cyclic compound	GO:0071407	202	0.073
response to decreased oxygen levels	GO:0036293	237	0.072
protein phosphorylation	GO:0006468	345	0.071
peptidyl amino acid modification	GO:0018193	126	0.071
purine nucleotide biosynthetic process	GO:0006164	83	0.070
secretion	GO:0046903	307	0.070
chemical homeostasis	GO:0048878	292	0.069	Rat
single organism intracellular transport	GO:1902582	166	0.069	Yeast
receptor metabolic process	GO:0043112	18	0.069
nucleoside phosphate metabolic process	GO:0006753	283	0.068	Yeast Rat
monovalent inorganic cation transport	GO:0015672	172	0.067	Rat
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.066
endothelial cell proliferation	GO:0001935	20	0.066
establishment of protein localization	GO:0045184	141	0.065	Yeast
negative regulation of macromolecule metabolic process	GO:0010605	260	0.065
cellular amine metabolic process	GO:0044106	38	0.065
transcription dna templated	GO:0006351	377	0.065
cranial suture morphogenesis	GO:0060363	4	0.064
regulation of nervous system development	GO:0051960	264	0.063
positive regulation of cellular component organization	GO:0051130	200	0.063
male mating behavior	GO:0060179	3	0.063
positive regulation of cellular amine metabolic process	GO:0033240	3	0.062
nucleic acid templated transcription	GO:0097659	379	0.062
negative regulation of epithelial cell proliferation	GO:0050680	16	0.061
negative regulation of cell communication	GO:0010648	158	0.061
positive regulation of odontogenesis	GO:0042482	3	0.060
negative regulation of developmental process	GO:0051093	125	0.060
protein complex assembly	GO:0006461	263	0.059
negative regulation of transport	GO:0051051	136	0.059	Rat
release of cytochrome c from mitochondria	GO:0001836	8	0.059
positive regulation of locomotion	GO:0040017	102	0.059
nitrogen compound transport	GO:0071705	229	0.058
monocarboxylic acid metabolic process	GO:0032787	152	0.058
regulation of apoptotic process	GO:0042981	335	0.058	Rat
cellular response to amino acid starvation	GO:0034198	1	0.058
regulation of secretion by cell	GO:1903530	208	0.058
protein localization	GO:0008104	191	0.057	Yeast
multicellular organismal reproductive process	GO:0048609	233	0.057
regulation of cellular protein metabolic process	GO:0032268	267	0.056
intracellular signal transduction	GO:0035556	314	0.056
regulation of purine nucleotide metabolic process	GO:1900542	115	0.056	Yeast Rat
immune system process	GO:0002376	204	0.055
epithelial cell differentiation	GO:0030855	71	0.055
organ regeneration	GO:0031100	101	0.055
response to purine containing compound	GO:0014074	126	0.055
regulation of cellular component organization	GO:0051128	368	0.055
hormone secretion	GO:0046879	115	0.054
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.054
rna metabolic process	GO:0016070	406	0.054
regulation of rna biosynthetic process	GO:2001141	381	0.053
regulation of hormone levels	GO:0010817	187	0.052
regulation of neuron differentiation	GO:0045664	208	0.052
regulation of kinase activity	GO:0043549	117	0.052
regulation of secretion	GO:0051046	224	0.051
organelle organization	GO:0006996	266	0.051	Yeast Rat
female pregnancy	GO:0007565	122	0.050
positive regulation of cell development	GO:0010720	176	0.050
cellular component biogenesis	GO:0044085	368	0.049
mitochondrion organization	GO:0007005	35	0.049
regulation of cellular amine metabolic process	GO:0033238	8	0.049
response to external biotic stimulus	GO:0043207	221	0.049
protein transport	GO:0015031	132	0.049	Yeast
response to corticosteroid	GO:0031960	235	0.048
tissue development	GO:0009888	252	0.048
regeneration	GO:0031099	163	0.048
developmental process involved in reproduction	GO:0003006	159	0.048
carbohydrate derivative metabolic process	GO:1901135	346	0.047	Yeast Rat
amide transport	GO:0042886	105	0.047
circulatory system development	GO:0072359	134	0.047
purine containing compound metabolic process	GO:0072521	253	0.046	Yeast Rat
cellular response to stress	GO:0033554	269	0.046
regulation of response to stress	GO:0080134	126	0.046
lymphocyte homeostasis	GO:0002260	2	0.046
regulation of immune system process	GO:0002682	123	0.045
positive regulation of neurogenesis	GO:0050769	165	0.045
regulation of intracellular signal transduction	GO:1902531	218	0.044
development of primary sexual characteristics	GO:0045137	107	0.044
locomotion	GO:0040011	237	0.044
synaptic vesicle endocytosis	GO:0048488	4	0.044
response to monosaccharide	GO:0034284	159	0.043
embryo development	GO:0009790	49	0.043
ribose phosphate biosynthetic process	GO:0046390	87	0.042
response to acid chemical	GO:0001101	222	0.042
positive regulation of phosphorus metabolic process	GO:0010562	262	0.042
response to estradiol	GO:0032355	164	0.042
membrane fusion	GO:0061025	26	0.042	Rat
negative regulation of hormone secretion	GO:0046888	46	0.042
regulation of protein metabolic process	GO:0051246	289	0.041
cell morphogenesis involved in differentiation	GO:0000904	119	0.041
regulation of fat cell differentiation	GO:0045598	3	0.041
cell adhesion	GO:0007155	110	0.041
positive regulation of protein transport	GO:0051222	41	0.041
hormone transport	GO:0009914	121	0.040
regulation of behavior	GO:0050795	61	0.040
regulation of nucleic acid templated transcription	GO:1903506	380	0.040
nucleoside phosphate biosynthetic process	GO:1901293	102	0.040
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.040
organic acid metabolic process	GO:0006082	292	0.040
tube development	GO:0035295	89	0.040
positive regulation of signal transduction	GO:0009967	175	0.040
signal release	GO:0023061	145	0.040
regulation of cell adhesion	GO:0030155	52	0.040
gland development	GO:0048732	155	0.039
regulation of skeletal muscle tissue growth	GO:0048631	3	0.039
positive regulation of cellular biosynthetic process	GO:0031328	295	0.039
cellular response to insulin stimulus	GO:0032869	81	0.039
positive regulation of phosphorylation	GO:0042327	177	0.038
reproductive structure development	GO:0048608	128	0.038
positive regulation of isotype switching	GO:0045830	1	0.038
g protein coupled receptor signaling pathway	GO:0007186	242	0.038
peptidyl tyrosine modification	GO:0018212	72	0.037
secretion by cell	GO:0032940	248	0.037
regulation of phosphorylation	GO:0042325	248	0.037
response to camp	GO:0051591	91	0.037
cellular component assembly	GO:0022607	360	0.037
mirna metabolic process	GO:0010586	1	0.037
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.037
regulation of odontogenesis	GO:0042481	4	0.036
cerebral cortex cell migration	GO:0021795	4	0.036
craniofacial suture morphogenesis	GO:0097094	4	0.036
negative regulation of secretion by cell	GO:1903531	72	0.036
positive regulation of protein phosphorylation	GO:0001934	135	0.036
central nervous system development	GO:0007417	311	0.036	Rat
positive regulation of b cell mediated immunity	GO:0002714	2	0.036
positive regulation of intracellular signal transduction	GO:1902533	138	0.035
negative regulation of transcription dna templated	GO:0045892	116	0.035
apoptotic signaling pathway	GO:0097190	27	0.035
positive regulation of nervous system development	GO:0051962	178	0.034
negative regulation of rna metabolic process	GO:0051253	123	0.034
positive regulation of cell death	GO:0010942	184	0.034
positive regulation of gene expression	GO:0010628	244	0.034
proteolysis	GO:0006508	175	0.034
transcription from rna polymerase ii promoter	GO:0006366	252	0.034
single organism reproductive process	GO:0044702	297	0.034
response to insulin	GO:0032868	133	0.034
regulation of cellular response to stress	GO:0080135	49	0.034
response to oxygen levels	GO:0070482	265	0.034
negative regulation of cellular metabolic process	GO:0031324	281	0.033
response to mechanical stimulus	GO:0009612	134	0.033
negative regulation of apoptotic process	GO:0043066	181	0.033	Rat
positive regulation of programmed cell death	GO:0043068	157	0.033
regulation of neurogenesis	GO:0050767	247	0.033
regulation of epithelial to mesenchymal transition	GO:0010717	2	0.033
regulation of b cell mediated immunity	GO:0002712	2	0.033
regulation of apoptotic signaling pathway	GO:2001233	13	0.033
ribonucleotide biosynthetic process	GO:0009260	85	0.033
ear development	GO:0043583	21	0.032
cellular response to oxygen containing compound	GO:1901701	386	0.032
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.032	Rat
regulation of mapk cascade	GO:0043408	116	0.032
chemotaxis	GO:0006935	66	0.032
multi multicellular organism process	GO:0044706	138	0.032
regulation of cell differentiation	GO:0045595	320	0.031
single organism membrane organization	GO:0044802	74	0.031	Rat
cell morphogenesis	GO:0000902	142	0.031
establishment of organelle localization	GO:0051656	37	0.031	Yeast
positive regulation of protein metabolic process	GO:0051247	178	0.031
response to vitamin	GO:0033273	131	0.031
regulation of nucleotide metabolic process	GO:0006140	117	0.031	Yeast Rat
regulation of multicellular organismal development	GO:2000026	376	0.031
response to organophosphorus	GO:0046683	102	0.031
tissue remodeling	GO:0048771	40	0.030
somatic stem cell division	GO:0048103	2	0.030
head development	GO:0060322	247	0.030	Rat
cellular response to peptide hormone stimulus	GO:0071375	120	0.030
inner ear receptor cell differentiation	GO:0060113	2	0.030
regulation of cell proliferation	GO:0042127	359	0.030
response to temperature stimulus	GO:0009266	94	0.030
skin morphogenesis	GO:0043589	2	0.030
single organism organelle organization	GO:1902589	180	0.029	Rat
cellular component morphogenesis	GO:0032989	155	0.029
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.029
response to ketone	GO:1901654	182	0.029
regulation of peptide secretion	GO:0002791	82	0.029
regulation of organ morphogenesis	GO:2000027	22	0.029
b cell activation involved in immune response	GO:0002312	1	0.029
response to reactive oxygen species	GO:0000302	120	0.029	Rat
response to lead ion	GO:0010288	33	0.028
intracellular protein transport	GO:0006886	79	0.028	Yeast
regulation of muscle system process	GO:0090257	79	0.028
sensory perception	GO:0007600	101	0.028	Rat
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.028
response to biotic stimulus	GO:0009607	226	0.028
carbohydrate derivative biosynthetic process	GO:1901137	124	0.028
response to wounding	GO:0009611	254	0.028
intracellular receptor signaling pathway	GO:0030522	35	0.027
regulation of establishment of planar polarity	GO:0090175	2	0.027
regulation of immunoglobulin mediated immune response	GO:0002889	2	0.027
glial cell differentiation	GO:0010001	65	0.027
response to glucocorticoid	GO:0051384	223	0.027
positive regulation of cyclic nucleotide metabolic process	GO:0030801	37	0.026
negative regulation of rna biosynthetic process	GO:1902679	118	0.026
negative regulation of secretion	GO:0051048	82	0.026
positive regulation of cell projection organization	GO:0031346	111	0.026
cell migration	GO:0016477	197	0.026
protein complex biogenesis	GO:0070271	263	0.026
response to hexose	GO:0009746	144	0.026
regulation of sodium ion transport	GO:0002028	21	0.026
reproductive process	GO:0022414	372	0.025	Yeast
cellular protein localization	GO:0034613	122	0.025	Yeast
growth	GO:0040007	165	0.025
regulation of cellular localization	GO:0060341	263	0.025	Yeast
positive regulation of protein serine threonine kinase activity	GO:0071902	52	0.025
regulation of phosphorus metabolic process	GO:0051174	349	0.025
response to mineralocorticoid	GO:0051385	49	0.025
positive regulation of intracellular protein transport	GO:0090316	20	0.025
digestive system development	GO:0055123	41	0.025
jnk cascade	GO:0007254	28	0.025
mapk cascade	GO:0000165	140	0.025
regulation of jnk cascade	GO:0046328	19	0.025
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.025
cellular homeostasis	GO:0019725	252	0.025	Rat
cyclic nucleotide metabolic process	GO:0009187	80	0.025
brain development	GO:0007420	247	0.025	Rat
regulation of stress activated protein kinase signaling cascade	GO:0070302	23	0.025
regulation of cell cycle arrest	GO:0071156	2	0.024
gastrulation	GO:0007369	2	0.024
purine ribonucleotide metabolic process	GO:0009150	227	0.024	Yeast Rat
cell junction maintenance	GO:0034331	1	0.024
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.024
single organism carbohydrate metabolic process	GO:0044723	118	0.024
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.024
regulation of cellular ketone metabolic process	GO:0010565	27	0.024
nucleotide biosynthetic process	GO:0009165	98	0.024
regulation of protein phosphorylation	GO:0001932	183	0.024
cell cycle	GO:0007049	101	0.024
regulation of phosphate metabolic process	GO:0019220	349	0.024
hepaticobiliary system development	GO:0061008	90	0.023
nucleoside monophosphate biosynthetic process	GO:0009124	28	0.023
cyclic purine nucleotide metabolic process	GO:0052652	62	0.023
response to activity	GO:0014823	73	0.023
peptide secretion	GO:0002790	86	0.023
sensory organ development	GO:0007423	74	0.023
response to corticosterone	GO:0051412	40	0.023
negative regulation of multicellular organismal process	GO:0051241	203	0.023
regulation of transcription dna templated	GO:0006355	374	0.023
response to starvation	GO:0042594	59	0.023
sexual reproduction	GO:0019953	148	0.023	Yeast
regulation of cell migration	GO:0030334	128	0.023
organic substance catabolic process	GO:1901575	316	0.023	Yeast Rat
organophosphate metabolic process	GO:0019637	370	0.022	Yeast Rat
response to glucose	GO:0009749	136	0.022
negative regulation of homeostatic process	GO:0032845	47	0.022
ovulation cycle	GO:0042698	67	0.022
innate immune response	GO:0045087	35	0.022
regulation of organelle organization	GO:0033043	80	0.022
negative regulation of mitochondrion organization	GO:0010823	2	0.022
cell part morphogenesis	GO:0032990	123	0.022
single organism biosynthetic process	GO:0044711	342	0.022
positive regulation of cellular protein metabolic process	GO:0032270	167	0.022
regulation of blood vessel endothelial cell migration	GO:0043535	4	0.022
regulation of transferase activity	GO:0051338	123	0.022
cellular chemical homeostasis	GO:0055082	247	0.022	Rat
carbohydrate homeostasis	GO:0033500	75	0.021
erbb signaling pathway	GO:0038127	23	0.021
regulation of hormone secretion	GO:0046883	106	0.021
regulation of sequence specific dna binding transcription factor activity	GO:0051090	35	0.021
ameboidal type cell migration	GO:0001667	26	0.021
insulin secretion	GO:0030073	69	0.021
epithelial cell proliferation	GO:0050673	54	0.021
gliogenesis	GO:0042063	93	0.021
positive regulation of neuron projection development	GO:0010976	99	0.021
immune response	GO:0006955	104	0.021
positive regulation of mapk cascade	GO:0043410	92	0.021
establishment of planar polarity	GO:0001736	1	0.021
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.021
regulation of vesicle mediated transport	GO:0060627	81	0.021
cellular macromolecular complex assembly	GO:0034622	58	0.021
mesoderm development	GO:0007498	2	0.021
mitochondrial transport	GO:0006839	19	0.021
protein homotetramerization	GO:0051289	25	0.021
developmental growth	GO:0048589	100	0.021
regulation of protein localization	GO:0032880	81	0.021	Yeast
positive regulation of cellular component movement	GO:0051272	102	0.021
cellular response to metal ion	GO:0071248	55	0.020
aging	GO:0007568	241	0.020	Rat
erk1 and erk2 cascade	GO:0070371	48	0.020
neural precursor cell proliferation	GO:0061351	23	0.020
somatic diversification of immune receptors via germline recombination within a single locus	GO:0002562	2	0.020
negative regulation of phosphate metabolic process	GO:0045936	80	0.020
protein maturation	GO:0051604	68	0.020
camp metabolic process	GO:0046058	63	0.020
stress activated protein kinase signaling cascade	GO:0031098	37	0.020
epithelium migration	GO:0090132	19	0.020
negative regulation of programmed cell death	GO:0043069	183	0.020	Rat
hair cell differentiation	GO:0035315	2	0.020
motor neuron axon guidance	GO:0008045	1	0.020
protein targeting	GO:0006605	61	0.020
embryonic morphogenesis	GO:0048598	14	0.020
biological adhesion	GO:0022610	110	0.020
positive regulation of apoptotic process	GO:0043065	154	0.020
peptide transport	GO:0015833	97	0.019
macromolecule localization	GO:0033036	252	0.019	Yeast
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	8	0.019
ribonucleoside biosynthetic process	GO:0042455	25	0.019
cellular process involved in reproduction in multicellular organism	GO:0022412	35	0.019
extrinsic apoptotic signaling pathway	GO:0097191	10	0.019
signal transduction by phosphorylation	GO:0023014	144	0.019
epithelial cell migration	GO:0010631	19	0.019
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.019
cellular macromolecule localization	GO:0070727	122	0.019	Yeast
cellular response to lipid	GO:0071396	201	0.019
muscle organ development	GO:0007517	50	0.019
cell cycle checkpoint	GO:0000075	2	0.019
nucleoside triphosphate metabolic process	GO:0009141	144	0.019	Yeast Rat
taxis	GO:0042330	67	0.019
catabolic process	GO:0009056	351	0.019	Yeast Rat
regulation of immune response	GO:0050776	55	0.018
nucleobase containing small molecule metabolic process	GO:0055086	316	0.018	Yeast Rat
regulation of metal ion transport	GO:0010959	118	0.018
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.018
positive regulation of kinase activity	GO:0033674	77	0.018
response to hydrogen peroxide	GO:0042542	89	0.018	Rat
cell projection morphogenesis	GO:0048858	123	0.018
cytokine mediated signaling pathway	GO:0019221	43	0.018
lipid metabolic process	GO:0006629	283	0.018
multi organism reproductive process	GO:0044703	262	0.018	Yeast
negative regulation of protein phosphorylation	GO:0001933	44	0.018
regulation of system process	GO:0044057	208	0.017
cellular response to oxidative stress	GO:0034599	76	0.017
regulation of cellular component biogenesis	GO:0044087	86	0.017
positive regulation of map kinase activity	GO:0043406	46	0.017
epidermal growth factor receptor signaling pathway	GO:0007173	23	0.017
negative regulation of protein metabolic process	GO:0051248	114	0.017
generation of precursor metabolites and energy	GO:0006091	62	0.017
peptide hormone secretion	GO:0030072	84	0.017
metanephric renal vesicle morphogenesis	GO:0072283	3	0.017
regulatory t cell differentiation	GO:0045066	2	0.017
negative regulation of immune system process	GO:0002683	39	0.017
defense response	GO:0006952	194	0.017
single fertilization	GO:0007338	3	0.017
inner ear development	GO:0048839	21	0.017
positive regulation of immune response	GO:0050778	42	0.017
response to amino acid	GO:0043200	75	0.017
sodium ion transport	GO:0006814	82	0.017
tissue regeneration	GO:0042246	36	0.017
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.017	Rat
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.016
cellular response to molecule of bacterial origin	GO:0071219	56	0.016
regulation of cell projection organization	GO:0031344	175	0.016
cell activation	GO:0001775	97	0.016
cellular response to peptide	GO:1901653	133	0.016
purine nucleotide metabolic process	GO:0006163	229	0.016	Yeast Rat
epithelium development	GO:0060429	96	0.016
negative regulation of phosphorylation	GO:0042326	57	0.016
angiogenesis	GO:0001525	53	0.016
negative regulation of muscle hypertrophy	GO:0014741	3	0.016
positive regulation of cell motility	GO:2000147	97	0.016
positive regulation of rna metabolic process	GO:0051254	203	0.016
synaptic vesicle recycling	GO:0036465	5	0.016
regulation of nucleotide biosynthetic process	GO:0030808	47	0.016
chordate embryonic development	GO:0043009	18	0.016
negative regulation of cellular biosynthetic process	GO:0031327	161	0.016
regulation of peptide hormone secretion	GO:0090276	80	0.016
purine nucleoside monophosphate biosynthetic process	GO:0009127	20	0.016
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.016
negative regulation of release of sequestered calcium ion into cytosol	GO:0051280	4	0.015
cellular response to cytokine stimulus	GO:0071345	127	0.015
positive regulation of cell proliferation	GO:0008284	249	0.015
cell cycle process	GO:0022402	57	0.015
carbohydrate catabolic process	GO:0016052	40	0.015
maternal process involved in female pregnancy	GO:0060135	38	0.015
thyroid gland development	GO:0030878	1	0.015
cellular response to reactive oxygen species	GO:0034614	55	0.015
reactive oxygen species biosynthetic process	GO:1903409	8	0.015
dna geometric change	GO:0032392	4	0.015
cyclic nucleotide biosynthetic process	GO:0009190	63	0.015
peptidyl serine modification	GO:0018209	34	0.015
vesicle localization	GO:0051648	33	0.015
cellular response to lipopolysaccharide	GO:0071222	55	0.015
positive regulation of camp metabolic process	GO:0030816	31	0.015
negative regulation of catalytic activity	GO:0043086	103	0.015
oxidation reduction process	GO:0055114	304	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.015	Yeast Rat
positive regulation of histone phosphorylation	GO:0033129	3	0.015
reactive nitrogen species metabolic process	GO:2001057	1	0.014
transmembrane transport	GO:0055085	412	0.014
defense response to gram negative bacterium	GO:0050829	3	0.014
small gtpase mediated signal transduction	GO:0007264	36	0.014
homeostatic process	GO:0042592	331	0.014	Rat
single organism behavior	GO:0044708	130	0.014
positive regulation of neuron differentiation	GO:0045666	126	0.014
atp metabolic process	GO:0046034	72	0.014
regulation of catabolic process	GO:0009894	113	0.014	Yeast Rat
positive regulation of cyclic nucleotide biosynthetic process	GO:0030804	34	0.014
cellular lipid metabolic process	GO:0044255	208	0.014
purine nucleoside biosynthetic process	GO:0042451	21	0.014
cytoplasmic transport	GO:0016482	115	0.014	Yeast
nucleotide metabolic process	GO:0009117	279	0.014	Yeast Rat
ras protein signal transduction	GO:0007265	29	0.014
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
salivary gland development	GO:0007431	3	0.014
regulation of epithelial cell migration	GO:0010632	17	0.014
regulation of nucleocytoplasmic transport	GO:0046822	28	0.014	Yeast
chemosensory behavior	GO:0007635	2	0.014
positive regulation of nucleocytoplasmic transport	GO:0046824	17	0.014
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.014
response to oxidative stress	GO:0006979	186	0.014	Rat
single organism catabolic process	GO:0044712	283	0.014	Yeast Rat
ossification	GO:0001503	70	0.013
ovulation cycle process	GO:0022602	50	0.013
regulation of hydrolase activity	GO:0051336	143	0.013	Yeast Rat
embryo development ending in birth or egg hatching	GO:0009792	22	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.013
regulation of peptide transport	GO:0090087	87	0.013
cellular component maintenance	GO:0043954	4	0.013
negative regulation of molecular function	GO:0044092	133	0.013
fatty acid metabolic process	GO:0006631	99	0.013
cellular response to external stimulus	GO:0071496	118	0.013
regulation of membrane potential	GO:0042391	110	0.013
cellular response to nitrogen compound	GO:1901699	210	0.013
positive regulation of purine nucleotide biosynthetic process	GO:1900373	36	0.013
regulation of muscle organ development	GO:0048634	26	0.013
single organism cellular localization	GO:1902580	102	0.013	Yeast
protein complex subunit organization	GO:0071822	302	0.013

Gnai2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.017
	disease of anatomical entity	DOID:7	0	0.017

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