Rattus norvegicus

116 known processes

Hes1

hairy and enhancer of split 1 (Drosophila)

Hes1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of nucleic acid templated transcriptionGO:19035063800.715
regulation of transcription from rna polymerase ii promoterGO:00063572340.558
transcription from rna polymerase ii promoterGO:00063662520.517
rna metabolic processGO:00160704060.509
nucleic acid templated transcriptionGO:00976593790.492
transcription dna templatedGO:00063513770.484
negative regulation of cellular biosynthetic processGO:00313271610.443
negative regulation of nucleobase containing compound metabolic processGO:00459341530.423
regulation of rna metabolic processGO:00512523910.420
regulation of multicellular organismal developmentGO:20000263760.399
negative regulation of nucleic acid templated transcriptionGO:19035071170.396
regulation of transcription dna templatedGO:00063553740.378
positive regulation of multicellular organismal processGO:00512403870.374
rna biosynthetic processGO:00327743800.369
regulation of rna biosynthetic processGO:20011413810.365
regulation of molecular functionGO:00650093980.328
cellular response to endogenous stimulusGO:00714953770.317
negative regulation of metabolic processGO:00098923310.293
negative regulation of rna metabolic processGO:00512531230.286
negative regulation of cellular metabolic processGO:00313242810.278
regulation of cell differentiationGO:00455953200.266
negative regulation of biosynthetic processGO:00098901680.237
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.226
programmed cell deathGO:00125013920.220
negative regulation of macromolecule biosynthetic processGO:00105581480.217
negative regulation of macromolecule metabolic processGO:00106052600.215
anatomical structure morphogenesisGO:00096532980.214
negative regulation of transcription dna templatedGO:00458921160.211
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.206
tissue developmentGO:00098882520.206
regulation of signal transductionGO:00099663180.205
negative regulation of gene expressionGO:00106291990.198
negative regulation of nitrogen compound metabolic processGO:00511721610.189
cellular response to organonitrogen compoundGO:00714171970.183
regulation of neurogenesisGO:00507672470.177
regulation of protein metabolic processGO:00512462890.176
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.173
neuron differentiationGO:00301823680.166
positive regulation of developmental processGO:00510942830.164
positive regulation of transcription dna templatedGO:00458931970.158
negative regulation of rna biosynthetic processGO:19026791180.154
cellular response to oxygen containing compoundGO:19017013860.152
positive regulation of cell differentiationGO:00455972170.149
response to extracellular stimulusGO:00099913800.147
response to peptideGO:19016522920.146
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.141
rhythmic processGO:00485111560.141
response to growth factorGO:00708481890.141
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.137
positive regulation of nitrogen compound metabolic processGO:00511733340.136
regulation of nervous system developmentGO:00519602640.135
protein phosphorylationGO:00064683450.135
regulation of phosphate metabolic processGO:00192203490.131
regulation of neuron differentiationGO:00456642080.126
regulation of phosphorus metabolic processGO:00511743490.126
positive regulation of macromolecule biosynthetic processGO:00105572470.125
response to woundingGO:00096112540.122
response to inorganic substanceGO:00100353770.121
cellular response to nitrogen compoundGO:19016992100.119
negative regulation of cell differentiationGO:0045596990.119
positive regulation of rna metabolic processGO:00512542030.118
reproductive processGO:00224143720.118
response to nutrient levelsGO:00316673700.117
immune system processGO:00023762040.116
positive regulation of rna biosynthetic processGO:19026801970.116
regulation of cellular protein metabolic processGO:00322682670.115
apoptotic processGO:00069153810.114
negative regulation of developmental processGO:00510931250.114
response to acid chemicalGO:00011012220.113
regulation of catalytic activityGO:00507903040.111
signal transduction by phosphorylationGO:00230141440.111
regulation of apoptotic processGO:00429813350.110
intracellular signal transductionGO:00355563140.110
positive regulation of cell communicationGO:00106472710.110
regulation of programmed cell deathGO:00430673410.106
neuron developmentGO:00486662860.102
regulation of cell developmentGO:00602842630.101
cellular amino acid metabolic processGO:00065201070.100
positive regulation of response to stimulusGO:00485842850.099
organic acid metabolic processGO:00060822920.098
regulation of cellular component organizationGO:00511283680.097
cell adhesionGO:00071551100.097
positive regulation of nucleobase containing compound metabolic processGO:00459353190.096
positive regulation of biosynthetic processGO:00098913190.095
response to metal ionGO:00100382530.095
bmp signaling pathwayGO:003050940.095
cellular response to stressGO:00335542690.094
regulation of phosphorylationGO:00423252480.093
cellular response to hormone stimulusGO:00328702470.090
single organism reproductive processGO:00447022970.090
negative regulation of response to stimulusGO:00485851550.089
enzyme linked receptor protein signaling pathwayGO:00071671160.089
circulatory system processGO:00030131830.087
response to decreased oxygen levelsGO:00362932370.085
response to other organismGO:00517072200.083
positive regulation of signalingGO:00230562700.083
cellular response to peptideGO:19016531330.082
positive regulation of cellular biosynthetic processGO:00313282950.082
regulation of protein phosphorylationGO:00019321830.081
positive regulation of gene expressionGO:00106282440.080
neuron projection developmentGO:00311752730.080
response to glucocorticoidGO:00513842230.079
response to oxygen levelsGO:00704822650.079
cell projection morphogenesisGO:00488581230.078
cell motilityGO:00488702020.077
reproductive system developmentGO:00614581280.077
circulatory system developmentGO:00723591340.077
regulation of immune system processGO:00026821230.076
cellular component morphogenesisGO:00329891550.075
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010060.074
regulation of protein modification processGO:00313991940.074
ossificationGO:0001503700.071
locomotionGO:00400112370.071
negative regulation of apoptotic processGO:00430661810.070
oxoacid metabolic processGO:00434362900.070
positive regulation of cellular protein metabolic processGO:00322701670.070
mapk cascadeGO:00001651400.069
localization of cellGO:00516742020.069
regulation of cellular localizationGO:00603412630.068
heart morphogenesisGO:000300730.068
behaviorGO:00076102050.068
positive regulation of nervous system developmentGO:00519621780.067
cellular component biogenesisGO:00440853680.067
regenerationGO:00310991630.066
regulation of cell projection organizationGO:00313441750.066
cellular response to organic cyclic compoundGO:00714072020.064
response to peptide hormoneGO:00434342780.064
positive regulation of nucleic acid templated transcriptionGO:19035081970.064
regulation of cellular amino acid metabolic processGO:000652120.063
cellular component assemblyGO:00226073600.063
cellular ketone metabolic processGO:0042180510.062
cellular response to external stimulusGO:00714961180.062
multi organism reproductive processGO:00447032620.062
negative regulation of multicellular organismal processGO:00512412030.062
positive regulation of immune system processGO:0002684900.061
central nervous system developmentGO:00074173110.061
kidney developmentGO:0001822670.061
catabolic processGO:00090563510.061
neuron projection morphogenesisGO:00488121220.061
regulation of cellular amine metabolic processGO:003323880.060
positive regulation of phosphorylationGO:00423271770.059
tube developmentGO:0035295890.059
epithelium developmentGO:0060429960.059
regulation of cell migrationGO:00303341280.059
regulation of cellular ketone metabolic processGO:0010565270.059
organelle organizationGO:00069962660.059
cell morphogenesis involved in neuron differentiationGO:00486671060.058
response to hypoxiaGO:00016662310.058
protein localizationGO:00081041910.058
cellular response to growth factor stimulusGO:00713631620.057
response to ketoneGO:19016541820.057
regulation of mapk cascadeGO:00434081160.057
positive regulation of cell developmentGO:00107201760.057
organic substance catabolic processGO:19015753160.057
positive regulation of phosphate metabolic processGO:00459372620.056
carboxylic acid metabolic processGO:00197522890.056
multicellular organism reproductionGO:00325042330.055
amine metabolic processGO:0009308380.055
positive regulation of phosphorus metabolic processGO:00105622620.055
circadian rhythmGO:0007623880.055
gland developmentGO:00487321550.055
macromolecule localizationGO:00330362520.055
protein complex subunit organizationGO:00718223020.054
negative regulation of molecular functionGO:00440921330.054
organ morphogenesisGO:0009887750.054
macromolecular complex subunit organizationGO:00439333390.054
regulation of neuron projection developmentGO:00109751610.053
response to corticosteroidGO:00319602350.053
liver developmentGO:0001889900.052
positive regulation of signal transductionGO:00099671750.052
response to bacteriumGO:00096172000.052
cell cell signalingGO:00072673350.052
negative regulation of signalingGO:00230571570.052
single organism organelle organizationGO:19025891800.051
regulation of system processGO:00440572080.051
response to cytokineGO:00340972150.051
positive regulation of molecular functionGO:00440932300.050
cellular amine metabolic processGO:0044106380.050
cell migrationGO:00164771970.050
single organism cellular localizationGO:19025801020.050
neurological system processGO:00508772190.049
urogenital system developmentGO:0001655780.049
positive regulation of neurogenesisGO:00507691650.049
cardiac chamber developmentGO:000320510.049
positive regulation of protein phosphorylationGO:00019341350.048
reproductionGO:00000032450.048
positive regulation of cellular component organizationGO:00511302000.048
negative regulation of programmed cell deathGO:00430691830.048
cellular lipid metabolic processGO:00442552080.048
response to oxidative stressGO:00069791860.047
homeostatic processGO:00425923310.046
negative regulation of cell deathGO:00605482290.046
positive regulation of cell proliferationGO:00082842490.046
regulation of cell proliferationGO:00421273590.045
carbohydrate derivative metabolic processGO:19011353460.045
response to monosaccharideGO:00342841590.045
regulation of intracellular signal transductionGO:19025312180.044
response to reactive oxygen speciesGO:00003021200.043
cell projection organizationGO:00300303020.043
positive regulation of cell deathGO:00109421840.043
cell morphogenesis involved in differentiationGO:00009041190.043
developmental process involved in reproductionGO:00030061590.043
response to campGO:0051591910.043
anatomical structure formation involved in morphogenesisGO:0048646830.042
negative regulation of cell communicationGO:00106481580.042
biological adhesionGO:00226101100.042
cellular response to acid chemicalGO:0071229750.042
multicellular organismal reproductive processGO:00486092330.042
cell morphogenesisGO:00009021420.041
response to nutrientGO:00075842480.041
regulation of cellular component movementGO:00512701500.041
positive regulation of cellular amino acid metabolic processGO:004576410.041
peptidyl amino acid modificationGO:00181931260.041
negative regulation of neurogenesisGO:0050768780.041
nucleobase containing small molecule metabolic processGO:00550863160.041
negative regulation of nervous system developmentGO:0051961790.040
response to external biotic stimulusGO:00432072210.040
positive regulation of protein metabolic processGO:00512471780.040
chemical homeostasisGO:00488782920.040
positive regulation of protein modification processGO:00314011420.040
blood circulationGO:00080151830.039
cardiovascular system developmentGO:00723581340.039
single organism intracellular transportGO:19025821660.039
positive regulation of cell motilityGO:2000147970.039
positive regulation of cellular amine metabolic processGO:003324030.038
cellular component movementGO:00069282480.038
response to toxic substanceGO:00096361330.038
anterior posterior pattern specificationGO:000995210.038
regulation of cell motilityGO:20001451310.038
cellular catabolic processGO:00442482950.037
response to carbohydrateGO:00097431830.037
proteolysisGO:00065081750.037
actin filament based processGO:0030029860.037
response to molecule of bacterial originGO:00022371940.037
positive regulation of neuron differentiationGO:00456661260.036
response to starvationGO:0042594590.036
regulation of anatomical structure sizeGO:00900661350.035
regulation of hydrolase activityGO:00513361430.035
cell part morphogenesisGO:00329901230.035
regulation of locomotionGO:00400121480.035
growthGO:00400071650.035
epithelial cell differentiationGO:0030855710.035
cellular response to peptide hormone stimulusGO:00713751200.035
cellular response to lipidGO:00713962010.035
female pregnancyGO:00075651220.034
secretionGO:00469033070.034
negative regulation of cell developmentGO:0010721820.034
gastrulationGO:000736920.034
response to biotic stimulusGO:00096072260.034
response to estrogenGO:00436272320.034
reproductive structure developmentGO:00486081280.033
head developmentGO:00603222470.033
negative regulation of neuron differentiationGO:0045665620.033
regulation of stem cell differentiationGO:200073620.033
immune system developmentGO:0002520410.033
cell cycleGO:00070491010.033
single organism catabolic processGO:00447122830.033
axis specificationGO:000979840.033
positive regulation of cell projection organizationGO:00313461110.033
intracellular transportGO:00469071850.033
renal system developmentGO:0072001670.033
hepaticobiliary system developmentGO:0061008900.033
lipid metabolic processGO:00066292830.032
protein complex biogenesisGO:00702712630.032
regulation of secretion by cellGO:19035302080.032
negative regulation of signal transductionGO:0009968830.032
heart valve morphogenesisGO:000317910.032
regulation of transferase activityGO:00513381230.032
regulation of cell morphogenesis involved in differentiationGO:0010769720.032
sensory organ developmentGO:0007423740.032
cytoskeleton organizationGO:00070101110.031
cellular macromolecule localizationGO:00707271220.031
brain developmentGO:00074202470.031
organ regenerationGO:00311001010.031
response to lipopolysaccharideGO:00324961910.031
response to hexoseGO:00097461440.030
regulation of canonical wnt signaling pathwayGO:006082840.030
protein complex assemblyGO:00064612630.030
positive regulation of transportGO:00510502450.030
gliogenesisGO:0042063930.030
stem cell maintenanceGO:001982760.030
positive regulation of programmed cell deathGO:00430681570.030
response to insulinGO:00328681330.030
cellular chemical homeostasisGO:00550822470.029
regulation of protein localizationGO:0032880810.029
wound healingGO:00420601220.029
cellular protein localizationGO:00346131220.029
defense responseGO:00069521940.029
hematopoietic or lymphoid organ developmentGO:0048534360.028
protein transportGO:00150311320.028
negative regulation of protein metabolic processGO:00512481140.028
sexual reproductionGO:00199531480.028
regulation of kinase activityGO:00435491170.028
organophosphate metabolic processGO:00196373700.028
gonad developmentGO:00084061040.028
positive regulation of neuron projection developmentGO:0010976990.028
positive regulation of locomotionGO:00400171020.027
response to purine containing compoundGO:00140741260.027
regulation of blood circulationGO:19035221100.026
action potentialGO:0001508540.026
cellular homeostasisGO:00197252520.026
regulation of cell adhesionGO:0030155520.026
cellular response to transforming growth factor beta stimulusGO:0071560410.026
response to organophosphorusGO:00466831020.026
carbohydrate metabolic processGO:00059751300.026
response to transforming growth factor betaGO:0071559460.026
nucleoside phosphate metabolic processGO:00067532830.026
development of primary sexual characteristicsGO:00451371070.026
multi multicellular organism processGO:00447061380.025
blood vessel developmentGO:0001568690.025
response to ethanolGO:00454711620.025
mesoderm developmentGO:000749820.025
negative regulation of cell proliferationGO:00082851190.025
cellular response to insulin stimulusGO:0032869810.025
positive regulation of kinase activityGO:0033674770.025
nitrogen compound transportGO:00717052290.025
negative regulation of cellular protein metabolic processGO:00322691060.025
gamete generationGO:00072761240.024
negative regulation of osteoblast differentiationGO:004566820.024
leukocyte differentiationGO:0002521300.024
establishment of protein localizationGO:00451841410.024
positive regulation of apoptotic processGO:00430651540.024
regulation of cellular component biogenesisGO:0044087860.024
secretion by cellGO:00329402480.024
sex differentiationGO:00075481130.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.024
positive regulation of catalytic activityGO:00430851840.024
single organism behaviorGO:00447081300.023
positive regulation of secretion by cellGO:19035321280.023
cell growthGO:00160491040.023
regulation of anatomical structure morphogenesisGO:00226031410.023
macromolecular complex assemblyGO:00650032730.023
cellular response to extracellular stimulusGO:0031668730.023
regulation of growthGO:00400081050.022
cellular response to nutrient levelsGO:0031669600.022
regulation of response to stressGO:00801341260.022
ras protein signal transductionGO:0007265290.022
dna metabolic processGO:0006259960.022
muscle system processGO:00030121150.022
hair cell differentiationGO:003531520.022
agingGO:00075682410.022
embryonic pattern specificationGO:000988010.022
regulation of ossificationGO:0030278320.022
response to calcium ionGO:0051592590.022
purine nucleotide metabolic processGO:00061632290.022
dendrite developmentGO:0016358720.022
learning or memoryGO:0007611900.022
regulation of proteasomal protein catabolic processGO:006113640.022
regulation of secretionGO:00510462240.022
response to hydrogen peroxideGO:0042542890.022
immune responseGO:00069551040.021
cognitionGO:0050890920.021
vascular process in circulatory systemGO:0003018960.021
purine containing compound metabolic processGO:00725212530.021
glial cell differentiationGO:0010001650.021
striated muscle cell developmentGO:0055002260.021
cellular response to lipopolysaccharideGO:0071222550.021
response to glucoseGO:00097491360.021
regulation of protein serine threonine kinase activityGO:0071900640.021
single organism biosynthetic processGO:00447113420.021
cell type specific apoptotic processGO:00972851340.021
hemopoiesisGO:0030097340.021
response to transition metal nanoparticleGO:19902671220.021
cellular response to oxidative stressGO:0034599760.021
regulation of bmp signaling pathwayGO:003051020.020
response to mineralocorticoidGO:0051385490.020
ribose phosphate metabolic processGO:00196932350.020
organophosphate biosynthetic processGO:00904071430.020
ion homeostasisGO:00508012120.020
eye morphogenesisGO:004859240.020
regulation of map kinase activityGO:0043405530.020
response to mechanical stimulusGO:00096121340.020
cardiac ventricle developmentGO:000323110.020
neuronal action potentialGO:0019228350.020
cell cycle checkpointGO:000007520.020
heart contractionGO:0060047570.019
positive regulation of protein kinase activityGO:0045860730.019
negative regulation of cellular component organizationGO:0051129830.019
muscle structure developmentGO:0061061870.019
regulation of osteoblast differentiationGO:0045667140.019
cellular nitrogen compound catabolic processGO:00442701630.019
positive regulation of transferase activityGO:0051347810.019
negative regulation of catalytic activityGO:00430861030.019
somatic stem cell maintenanceGO:003501920.019
actin cytoskeleton organizationGO:0030036730.019
intracellular protein transportGO:0006886790.019
regulation of blood vessel sizeGO:0050880890.019
cellular response to steroid hormone stimulusGO:0071383930.019
chromosome segregationGO:000705920.019
response to retinoic acidGO:0032526630.019
formation of primary germ layerGO:000170410.019
small gtpase mediated signal transductionGO:0007264360.019
regulation of synaptic transmissionGO:00508041410.019
ribonucleotide metabolic processGO:00092592310.019
regulation of cell cycleGO:0051726730.019
heterocycle catabolic processGO:00467001670.018
male gamete generationGO:0048232990.018
positive regulation of mapk cascadeGO:0043410920.018
spermatogenesisGO:0007283990.018
mechanoreceptor differentiationGO:004249020.018
carbohydrate derivative biosynthetic processGO:19011371240.018
reactive oxygen species metabolic processGO:0072593370.017
b cell differentiationGO:003018320.017
heart developmentGO:0007507720.017
purine ribonucleotide metabolic processGO:00091502270.017
axonogenesisGO:0007409710.017
response to amino acidGO:0043200750.017
regulation of neuron apoptotic processGO:0043523830.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
protein oligomerizationGO:00512591910.017
purine nucleoside metabolic processGO:00422781690.017
regulation of membrane potentialGO:00423911100.017
regulation of establishment of protein localizationGO:0070201690.017
positive regulation of intracellular signal transductionGO:19025331380.017
metal ion homeostasisGO:00550651860.017
membrane organizationGO:0061024940.017
transmission of nerve impulseGO:0019226420.017
cellular ion homeostasisGO:00068731840.017
response to radiationGO:00093141370.017
female sex differentiationGO:0046660590.017
regulation of dendrite developmentGO:0050773590.017
protein localization to membraneGO:0072657360.017
protein maturationGO:0051604680.017
regulation of organ formationGO:000315620.017
glycosyl compound metabolic processGO:19016571820.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.017
transforming growth factor beta receptor signaling pathwayGO:0007179180.016
heart processGO:0003015570.016
nucleotide metabolic processGO:00091172790.016
response to estradiolGO:00323551640.016
ribonucleoside metabolic processGO:00091191740.016
peptidyl tyrosine modificationGO:0018212720.016
axon developmentGO:0061564960.016
protein targetingGO:0006605610.016
regulation of cell growthGO:0001558850.016
regulation of fat cell differentiationGO:004559830.016
cellular response to oxygen levelsGO:0071453600.016
regulation of muscle system processGO:0090257790.016
cellular response to reactive oxygen speciesGO:0034614550.016
cell fate determinationGO:000170920.016
purine nucleoside catabolic processGO:00061521240.016
synaptic transmissionGO:00072682350.016
positive regulation of protein serine threonine kinase activityGO:0071902520.016
purine containing compound catabolic processGO:00725231380.016
negative regulation of canonical wnt signaling pathwayGO:009009040.016
osteoblast differentiationGO:0001649260.016
cellular response to cytokine stimulusGO:00713451270.016
cytoplasmic transportGO:00164821150.016
multicellular organismal signalingGO:0035637440.016
inner ear receptor cell differentiationGO:006011320.016
organonitrogen compound biosynthetic processGO:19015661670.016
regulation of hormone levelsGO:00108171870.016
leukocyte activationGO:0045321760.016
regulation of cellular catabolic processGO:00313291010.016
negative regulation of phosphate metabolic processGO:0045936800.015
purine ribonucleoside metabolic processGO:00461281680.015
regulation of tube sizeGO:0035150890.015
regulation of catabolic processGO:00098941130.015
blood vessel morphogenesisGO:0048514580.015
response to alkaloidGO:00432791320.015
nucleobase containing compound catabolic processGO:00346551520.015
organonitrogen compound catabolic processGO:19015651790.015
purine ribonucleotide catabolic processGO:00091541360.015
neuronal stem cell maintenanceGO:009715020.015
peptidyl tyrosine phosphorylationGO:0018108720.015
cellular response to molecule of bacterial originGO:0071219560.015
amide transportGO:00428861050.015
response to interleukin 1GO:0070555550.015
angiogenesisGO:0001525530.015
cofactor metabolic processGO:0051186950.015
cardiac muscle contractionGO:0060048270.015
ribonucleoside catabolic processGO:00424541260.015
vasculogenesisGO:000157030.015
protein localization to organelleGO:0033365570.015
alpha amino acid metabolic processGO:1901605710.015
neuron fate commitmentGO:004866340.014
single organism carbohydrate metabolic processGO:00447231180.014
taxisGO:0042330670.014
cell cycle processGO:0022402570.014
cation transportGO:00068123820.014
oxidation reduction processGO:00551143040.014
cellular response to starvationGO:0009267270.014
hematopoietic progenitor cell differentiationGO:000224420.014
heart valve developmentGO:000317010.014
regulation of protein kinase activityGO:00458591050.014
negative regulation of neuron projection developmentGO:0010977460.014
negative regulation of phosphorus metabolic processGO:0010563800.014
cellular response to follicle stimulating hormone stimulusGO:0071372130.014
positive regulation of cellular component biogenesisGO:0044089550.014

Hes1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.045
disease of anatomical entityDOID:700.045
cardiovascular system diseaseDOID:128700.023
sensory system diseaseDOID:005015500.020
disease of metabolismDOID:001466700.016
eye and adnexa diseaseDOID:149200.014