Rattus norvegicus

0 known processes

Klk1b21

kallikrein 1-related peptidase b21

(Aliases: KLK8,Klk1c8,rk8,rGK-8,Klk6)

Klk1b21 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442552080.237
Mouse
regulation of molecular functionGO:00650093980.202
Mouse
regulation of phosphate metabolic processGO:00192203490.190
Mouse
response to inorganic substanceGO:00100353770.167
response to extracellular stimulusGO:00099913800.154
Rat
intracellular signal transductionGO:00355563140.147
Mouse
reproductive processGO:00224143720.147
cation transportGO:00068123820.145
positive regulation of lipid kinase activityGO:009021820.143
Mouse
cell projection organizationGO:00300303020.143
Rat
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.136
Mouse
regulation of signal transductionGO:00099663180.133
inorganic ion transmembrane transportGO:00986602290.124
ion transmembrane transportGO:00342203650.112
cellular amide metabolic processGO:0043603440.103
Mouse
reproductionGO:00000032450.098
cellular chemical homeostasisGO:00550822470.097
lipid metabolic processGO:00066292830.095
Mouse
regulation of phosphorus metabolic processGO:00511743490.095
Mouse
response to acid chemicalGO:00011012220.091
response to nutrient levelsGO:00316673700.089
Rat
regulation of lipid metabolic processGO:0019216680.088
Mouse
cell cell signalingGO:00072673350.087
nitrogen compound transportGO:00717052290.085
phospholipid metabolic processGO:0006644610.084
Mouse
regulation of cellular localizationGO:00603412630.081
homeostatic processGO:00425923310.077
secretion by cellGO:00329402480.077
chemical homeostasisGO:00488782920.076
metal ion transportGO:00300012890.073
positive regulation of cellular biosynthetic processGO:00313282950.070
response to peptideGO:19016522920.069
inorganic cation transmembrane transportGO:00986622020.067
g protein coupled receptor signaling pathwayGO:00071862420.066
defense responseGO:00069521940.065
Mouse
positive regulation of developmental processGO:00510942830.065
divalent metal ion transportGO:00708381320.064
cellular calcium ion homeostasisGO:00068741600.063
cell motilityGO:00488702020.062
negative regulation of cellular metabolic processGO:00313242810.061
response to metal ionGO:00100382530.061
cellular metal ion homeostasisGO:00068751720.060
behaviorGO:00076102050.060
protein phosphorylationGO:00064683450.059
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.059
organic hydroxy compound transportGO:0015850770.058
regulation of cell differentiationGO:00455953200.058
Rat
multicellular organism reproductionGO:00325042330.057
response to estrogenGO:00436272320.055
negative regulation of metabolic processGO:00098923310.054
cell migrationGO:00164771970.052
positive regulation of protein metabolic processGO:00512471780.052
regulation of neuron differentiationGO:00456642080.052
Rat
response to nutrientGO:00075842480.052
Rat
oxoacid metabolic processGO:00434362900.051
multi organism reproductive processGO:00447032620.051
multicellular organismal reproductive processGO:00486092330.051
regulation of multicellular organismal developmentGO:20000263760.050
Rat
regulation of programmed cell deathGO:00430673410.050
cation homeostasisGO:00550801950.050
cellular component movementGO:00069282480.049
metal ion homeostasisGO:00550651860.048
fatty acid metabolic processGO:0006631990.046
regulation of catalytic activityGO:00507903040.046
Mouse
carboxylic acid metabolic processGO:00197522890.046
positive regulation of transportGO:00510502450.046
macromolecular complex assemblyGO:00650032730.045
regulation of intracellular signal transductionGO:19025312180.045
response to oxidative stressGO:00069791860.045
negative regulation of cell proliferationGO:00082851190.045
cation transmembrane transportGO:00986552630.044
organonitrogen compound biosynthetic processGO:19015661670.044
Mouse
cellular homeostasisGO:00197252520.044
cytosolic calcium ion homeostasisGO:00514801400.043
regulation of rna metabolic processGO:00512523910.043
cellular ion homeostasisGO:00068731840.043
regulation of cellular component organizationGO:00511283680.043
Rat
regulation of phosphorylationGO:00423252480.042
Mouse
locomotionGO:00400112370.042
response to corticosteroidGO:00319602350.042
regulation of nervous system developmentGO:00519602640.042
Rat
regulation of neuron projection developmentGO:00109751610.041
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.041
sexual reproductionGO:00199531480.041
organic acid metabolic processGO:00060822920.041
regulation of cellular ketone metabolic processGO:0010565270.041
negative regulation of cell deathGO:00605482290.041
cellular component biogenesisGO:00440853680.040
monocarboxylic acid metabolic processGO:00327871520.040
muscle system processGO:00030121150.040
Mouse
response to estradiolGO:00323551640.039
cellular catabolic processGO:00442482950.039
cellular divalent inorganic cation homeostasisGO:00725031620.039
secretionGO:00469033070.039
protein complex biogenesisGO:00702712630.038
rna metabolic processGO:00160704060.038
cellular component assemblyGO:00226073600.038
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.038
Mouse
cellular cation homeostasisGO:00300031800.037
immune system processGO:00023762040.037
response to carbohydrateGO:00097431830.037
single organism behaviorGO:00447081300.037
response to glucocorticoidGO:00513842230.037
cellular response to abiotic stimulusGO:0071214850.037
regulation of ion transportGO:00432692450.037
regulation of cell projection organizationGO:00313441750.036
Rat
cellular amine metabolic processGO:0044106380.036
positive regulation of phosphate metabolic processGO:00459372620.036
Mouse
vesicle mediated transportGO:00161921810.036
positive regulation of gene expressionGO:00106282440.035
synaptic transmissionGO:00072682350.035
regulation of protein metabolic processGO:00512462890.035
blood circulationGO:00080151830.034
Mouse Rat
glycerolipid metabolic processGO:0046486670.034
Mouse
organelle organizationGO:00069962660.034
positive regulation of cell communicationGO:00106472710.034
transcription dna templatedGO:00063513770.034
nucleic acid templated transcriptionGO:00976593790.033
regulation of apoptotic processGO:00429813350.033
response to peptide hormoneGO:00434342780.033
response to ethanolGO:00454711620.033
response to monosaccharideGO:00342841590.033
positive regulation of cell projection organizationGO:00313461110.033
carbohydrate derivative metabolic processGO:19011353460.033
regulation of blood circulationGO:19035221100.033
Rat
proteolysisGO:00065081750.032
Mouse Rat
positive regulation of ion transportGO:0043270940.032
regulation of cellular protein metabolic processGO:00322682670.032
cellular response to endogenous stimulusGO:00714953770.032
response to transition metal nanoparticleGO:19902671220.032
agingGO:00075682410.032
negative regulation of macromolecule metabolic processGO:00106052600.031
transmembrane transportGO:00550854120.031
positive regulation of cell proliferationGO:00082842490.031
adult locomotory behaviorGO:000834440.031
cellular macromolecule localizationGO:00707271220.031
calcium ion homeostasisGO:00550741620.030
negative regulation of transportGO:00510511360.030
single organism catabolic processGO:00447122830.030
single organism intracellular transportGO:19025821660.030
hormone secretionGO:00468791150.030
peptide biosynthetic processGO:004304330.030
Mouse
b cell differentiationGO:003018320.030
muscle contractionGO:0006936880.029
Mouse
negative regulation of response to stimulusGO:00485851550.029
regulation of metal ion transportGO:00109591180.029
rna biosynthetic processGO:00327743800.029
cellular lipid catabolic processGO:0044242370.029
regulation of cell developmentGO:00602842630.029
Rat
positive regulation of biosynthetic processGO:00098913190.029
response to purine containing compoundGO:00140741260.028
Rat
regulation of cell proliferationGO:00421273590.028
positive regulation of nitrogen compound metabolic processGO:00511733340.028
positive regulation of catalytic activityGO:00430851840.028
Mouse
negative regulation of nitrogen compound metabolic processGO:00511721610.028
small molecule biosynthetic processGO:00442831240.028
peptidyl amino acid modificationGO:00181931260.027
cellular response to oxygen containing compoundGO:19017013860.027
divalent inorganic cation homeostasisGO:00725071650.027
cellular response to cytokine stimulusGO:00713451270.027
brain renin angiotensin systemGO:000203530.027
Mouse
negative regulation of cell communicationGO:00106481580.027
intracellular transportGO:00469071850.027
circulatory system processGO:00030131830.027
Mouse Rat
negative regulation of signal transductionGO:0009968830.026
positive regulation of multicellular organismal processGO:00512403870.026
Rat
regulation of transcription dna templatedGO:00063553740.026
establishment of protein localizationGO:00451841410.026
negative regulation of cell differentiationGO:0045596990.026
small gtpase mediated signal transductionGO:0007264360.026
Mouse
heart morphogenesisGO:000300730.025
Mouse
anatomical structure morphogenesisGO:00096532980.025
Mouse
amine metabolic processGO:0009308380.025
organophosphate metabolic processGO:00196373700.025
Mouse
protein complex assemblyGO:00064612630.025
positive regulation of signalingGO:00230562700.025
regulation of rna biosynthetic processGO:20011413810.025
regulation of neurogenesisGO:00507672470.024
Rat
response to cytokineGO:00340972150.024
regulation of cellular amino acid metabolic processGO:000652120.024
response to calcium ionGO:0051592590.024
response to biotic stimulusGO:00096072260.024
regulation of transmembrane transportGO:00347621220.024
cellular response to interleukin 1GO:0071347370.024
choline transportGO:001587140.023
neuron differentiationGO:00301823680.023
Rat
purine containing compound metabolic processGO:00725212530.023
regulation of immune system processGO:00026821230.023
signal releaseGO:00230611450.023
regulation of homeostatic processGO:00328441010.023
oxidation reduction processGO:00551143040.023
organonitrogen compound catabolic processGO:19015651790.023
immune effector processGO:0002252530.022
neuron developmentGO:00486662860.022
Rat
catabolic processGO:00090563510.022
positive regulation of rna metabolic processGO:00512542030.022
kidney developmentGO:0001822670.022
monoamine transportGO:0015844430.022
macromolecule localizationGO:00330362520.022
positive regulation of cell differentiationGO:00455972170.022
response to corticosteroneGO:0051412400.022
positive regulation of phosphorus metabolic processGO:00105622620.022
Mouse
regulation of cellular amine metabolic processGO:003323880.022
cellular amino acid metabolic processGO:00065201070.022
single organism reproductive processGO:00447022970.022
cellular ketone metabolic processGO:0042180510.022
cellular response to organonitrogen compoundGO:00714171970.021
negative regulation of molecular functionGO:00440921330.021
positive regulation of cellular component organizationGO:00511302000.021
negative regulation of programmed cell deathGO:00430691830.021
negative regulation of signalingGO:00230571570.021
response to hexoseGO:00097461440.021
response to interleukin 1GO:0070555550.020
regulation of anatomical structure sizeGO:00900661350.020
Mouse Rat
actin filament based processGO:0030029860.020
rhythmic processGO:00485111560.020
cellular response to lipidGO:00713962010.020
growthGO:00400071650.020
regulation of blood vessel sizeGO:0050880890.020
Mouse Rat
ion homeostasisGO:00508012120.020
organic substance catabolic processGO:19015753160.020
response to hydrogen peroxideGO:0042542890.020
positive regulation of transcription dna templatedGO:00458931970.020
positive regulation of neurogenesisGO:00507691650.020
positive regulation of cellular amine metabolic processGO:003324030.020
negative regulation of gene expressionGO:00106291990.019
cellular response to acid chemicalGO:0071229750.019
regulation of lipid kinase activityGO:004355070.019
Mouse
anion transportGO:00068201780.019
response to reactive oxygen speciesGO:00003021200.019
neuron projection developmentGO:00311752730.019
Rat
positive regulation of molecular functionGO:00440932300.019
Mouse
response to glucoseGO:00097491360.019
peptide transportGO:0015833970.019
divalent inorganic cation transportGO:00725111340.019
cellular response to nitrogen compoundGO:19016992100.019
positive regulation of kinase activityGO:0033674770.018
Mouse
regulation of growthGO:00400081050.018
insulin secretionGO:0030073690.018
response to external biotic stimulusGO:00432072210.018
response to bacteriumGO:00096172000.018
regulation of peptide hormone secretionGO:0090276800.018
inflammatory responseGO:00069541500.018
Mouse
response to woundingGO:00096112540.018
regulation of hydrolase activityGO:00513361430.018
protein complex subunit organizationGO:00718223020.018
nucleoside phosphate metabolic processGO:00067532830.018
negative regulation of cellular biosynthetic processGO:00313271610.018
urogenital system developmentGO:0001655780.018
mapk cascadeGO:00001651400.018
regulation of blood pressureGO:0008217830.018
Mouse
male sex differentiationGO:0046661640.018
macromolecular complex subunit organizationGO:00439333390.017
positive regulation of phosphorylationGO:00423271770.017
Mouse
multicellular organism growthGO:003526410.017
regulation of neuron deathGO:19012141150.017
cellular response to stressGO:00335542690.017
immune responseGO:00069551040.017
single organism cellular localizationGO:19025801020.017
monovalent inorganic cation transportGO:00156721720.017
synaptic growth at neuromuscular junctionGO:005112410.017
ribonucleotide metabolic processGO:00092592310.017
development of primary sexual characteristicsGO:00451371070.017
cellular response to organic cyclic compoundGO:00714072020.017
response to radiationGO:00093141370.017
response to ketoneGO:19016541820.017
regulation of sequence specific dna binding transcription factor activityGO:0051090350.017
regulation of ion transmembrane transportGO:00347651210.017
positive regulation of blood circulationGO:1903524650.017
Rat
gamete generationGO:00072761240.016
response to ammonium ionGO:0060359710.016
sensory perceptionGO:00076001010.016
spermatogenesisGO:0007283990.016
cellular component morphogenesisGO:00329891550.016
cognitionGO:0050890920.016
response to mineralocorticoidGO:0051385490.016
regulation of protein modification processGO:00313991940.016
amide transportGO:00428861050.016
positive regulation of lipid metabolic processGO:0045834330.016
Mouse
cellular protein localizationGO:00346131220.016
developmental process involved in reproductionGO:00030061590.016
multicellular organismal signalingGO:0035637440.016
fertilizationGO:000956630.016
organophosphate catabolic processGO:00464341480.016
circulatory system developmentGO:00723591340.016
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063572340.016
regulation of peptide secretionGO:0002791820.016
regulation of secretionGO:00510462240.016
reproductive system developmentGO:00614581280.016
regulation of transporter activityGO:0032409500.016
potassium ion transportGO:0006813970.016
response to growth factorGO:00708481890.015
respiratory system developmentGO:0060541450.015
cellular response to hormone stimulusGO:00328702470.015
negative regulation of rna biosynthetic processGO:19026791180.015
positive regulation of nucleic acid templated transcriptionGO:19035081970.015
carbohydrate derivative catabolic processGO:19011361470.015
regulation of secretion by cellGO:19035302080.015
alcohol metabolic processGO:0006066770.015
regulation of synaptic transmissionGO:00508041410.015
neurological system processGO:00508772190.015
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353190.015
programmed cell deathGO:00125013920.015
positive regulation of macromolecule biosynthetic processGO:00105572470.015
acute inflammatory responseGO:0002526580.015
Mouse
positive regulation of intracellular signal transductionGO:19025331380.015
regulation of protein phosphorylationGO:00019321830.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
response to oxygen levelsGO:00704822650.014
female pregnancyGO:00075651220.014
protein maturationGO:0051604680.014
Mouse
transmission of nerve impulseGO:0019226420.014
regulation of peptide transportGO:0090087870.014
comma shaped body morphogenesisGO:007204920.014
response to other organismGO:00517072200.014
apoptotic processGO:00069153810.014
learning or memoryGO:0007611900.014
positive regulation of rna biosynthetic processGO:19026801970.014
positive regulation of cell developmentGO:00107201760.014
single organism organelle organizationGO:19025891800.014
single organism biosynthetic processGO:00447113420.014
positive regulation of programmed cell deathGO:00430681570.014
hexose metabolic processGO:0019318580.014
positive regulation of neuron differentiationGO:00456661260.014
positive regulation of neuron projection developmentGO:0010976990.013
positive regulation of cell deathGO:00109421840.013
central nervous system developmentGO:00074173110.013
response to organophosphorusGO:00466831020.013
negative regulation of cellular protein metabolic processGO:00322691060.013
peptide hormone secretionGO:0030072840.013
response to hypoxiaGO:00016662310.013
regulation of response to stressGO:00801341260.013
chromosome segregationGO:000705920.013
positive regulation of nervous system developmentGO:00519621780.013
hormone transportGO:00099141210.013
erythrocyte differentiationGO:003021810.013
regulation of cellular catabolic processGO:00313291010.013
negative regulation of catalytic activityGO:00430861030.013
striated muscle contractionGO:0006941440.013
Mouse
negative regulation of developmental processGO:00510931250.013
cell type specific apoptotic processGO:00972851340.013
organic hydroxy compound biosynthetic processGO:1901617510.013
circadian sleep wake cycleGO:0042745230.013
cellular response to extracellular stimulusGO:0031668730.013
positive regulation of response to stimulusGO:00485842850.012
male gamete generationGO:0048232990.012
protein localization to nucleusGO:0034504390.012
regenerationGO:00310991630.012
lipid transportGO:0006869610.012
lipid biosynthetic processGO:00086101280.012
regulation of kinase activityGO:00435491170.012
Mouse
response to decreased oxygen levelsGO:00362932370.012
cell fate determinationGO:000170920.012
vascular process in circulatory systemGO:0003018960.012
Mouse Rat
cell morphogenesis involved in differentiationGO:00009041190.012
negative regulation of rna metabolic processGO:00512531230.012
positive regulation of hormone secretionGO:0046887650.012
response to vitaminGO:00332731310.012
protein processingGO:0016485680.012
Mouse
reactive oxygen species biosynthetic processGO:190340980.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
positive regulation of immune system processGO:0002684900.012
regulation of muscle system processGO:0090257790.012
monocarboxylic acid transportGO:0015718520.012
steroid metabolic processGO:0008202730.012
response to zinc ionGO:0010043390.012
signal transduction by phosphorylationGO:00230141440.012
purine ribonucleotide metabolic processGO:00091502270.012
negative regulation of biosynthetic processGO:00098901680.012
regulation of insulin secretionGO:0050796650.012
positive regulation of cellular protein metabolic processGO:00322701670.012
cellular macromolecular complex assemblyGO:0034622580.012
peptide metabolic processGO:0006518320.012
Mouse
response to axon injuryGO:0048678590.012
regulation of cell cycleGO:0051726730.011
gastrulationGO:000736920.011
circadian rhythmGO:0007623880.011
hematopoietic progenitor cell differentiationGO:000224420.011
antigen processing and presentationGO:001988220.011
head developmentGO:00603222470.011
positive regulation of calcium ion transportGO:0051928360.011
regulation of transferase activityGO:00513381230.011
Mouse
second messenger mediated signalingGO:0019932510.011
cellular response to external stimulusGO:00714961180.011
leukocyte cell cell adhesionGO:000715940.011
response to amino acidGO:0043200750.011
response to molecule of fungal originGO:000223830.011
reactive nitrogen species metabolic processGO:200105710.011
regulation of cellular component movementGO:00512701500.011
smooth muscle cell proliferationGO:0048659770.011
gonad developmentGO:00084061040.011
carbohydrate metabolic processGO:00059751300.011
regulation of immune responseGO:0050776550.011
nucleotide metabolic processGO:00091172790.011
male gonad developmentGO:0008584590.011
sex differentiationGO:00075481130.011
regulation of nucleic acid templated transcriptionGO:19035063800.011
positive regulation of signal transductionGO:00099671750.011
regulation of membrane potentialGO:00423911100.011
positive regulation of norepinephrine secretionGO:001070140.011
lipid catabolic processGO:0016042460.011
sleepGO:0030431300.011
positive regulation of lipid catabolic processGO:005099640.011
response to activityGO:0014823730.011
metanephric s shaped body morphogenesisGO:007228420.011
cellular response to oxidative stressGO:0034599760.011
regulation of protein targetingGO:1903533280.011
positive regulation of amine transportGO:0051954260.011
ossificationGO:0001503700.011
regulation of transmembrane transporter activityGO:0022898490.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
peptidyl tyrosine phosphorylationGO:0018108720.011
regulation of calcium ion transportGO:0051924770.011
jak stat cascadeGO:0007259260.010
purine nucleotide metabolic processGO:00061632290.010
vasoconstrictionGO:0042310540.010
Rat
negative regulation of cell cycle phase transitionGO:190198840.010
heart developmentGO:0007507720.010
Mouse
regulation of ion transmembrane transporter activityGO:0032412480.010
immune system developmentGO:0002520410.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
ribonucleoside catabolic processGO:00424541260.010
transcription from rna polymerase ii promoterGO:00063662520.010
chemosensory behaviorGO:000763520.010
regulation of hormone levelsGO:00108171870.010
response to retinoic acidGO:0032526630.010
hair follicle developmentGO:000194220.010
protein oligomerizationGO:00512591910.010
response to fatty acidGO:0070542650.010
tube developmentGO:0035295890.010
ras protein signal transductionGO:0007265290.010
regulation of catabolic processGO:00098941130.010
response to alkaloidGO:00432791320.010
Rat
response to tumor necrosis factorGO:0034612560.010
excretionGO:0007588240.010
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.010
positive regulation of apoptotic processGO:00430651540.010
negative regulation of secretionGO:0051048820.010

Klk1b21 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
nervous system diseaseDOID:86300.023
disease of metabolismDOID:001466700.013