IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

LOC100365112

carboxylesterase-like

(Aliases: Ces2)

Entrez: 100365112
RGD: 2319661
UniProtKB: O70177

Process Predictions
Disease Predictions

LOC100365112 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
halogenated hydrocarbon metabolic process	GO:0042197	4	0.584
alkaloid metabolic process	GO:0009820	3	0.367
carboxylic acid metabolic process	GO:0019752	289	0.340
exogenous drug catabolic process	GO:0042738	1	0.340
cellular response to xenobiotic stimulus	GO:0071466	19	0.287
oxoacid metabolic process	GO:0043436	290	0.247
arachidonic acid metabolic process	GO:0019369	20	0.243
monocarboxylic acid metabolic process	GO:0032787	152	0.238
organic acid metabolic process	GO:0006082	292	0.234
naphthalene containing compound metabolic process	GO:0090420	2	0.219
response to peptide hormone	GO:0043434	278	0.196
linoleic acid metabolic process	GO:0043651	4	0.193
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.192
response to xenobiotic stimulus	GO:0009410	23	0.187
cellular catabolic process	GO:0044248	295	0.162
coumarin metabolic process	GO:0009804	5	0.160
drug catabolic process	GO:0042737	1	0.155
lipid metabolic process	GO:0006629	283	0.150
fatty acid derivative metabolic process	GO:1901568	38	0.144
trichloroethylene metabolic process	GO:0018979	1	0.138
hepaticobiliary system development	GO:0061008	90	0.132
nicotine metabolic process	GO:0018933	1	0.130
long chain fatty acid metabolic process	GO:0001676	32	0.128
icosanoid metabolic process	GO:0006690	38	0.122
naphthalene metabolic process	GO:0018931	2	0.120
response to nutrient levels	GO:0031667	370	0.118
response to ketone	GO:1901654	182	0.106
response to molecule of bacterial origin	GO:0002237	194	0.106
response to metal ion	GO:0010038	253	0.106
response to nutrient	GO:0007584	248	0.102
fatty acid metabolic process	GO:0006631	99	0.100
response to sulfur dioxide	GO:0010477	3	0.096
biphenyl catabolic process	GO:0070980	2	0.092
4 chlorobiphenyl metabolic process	GO:0018880	1	0.080
organonitrogen compound biosynthetic process	GO:1901566	167	0.077
cellular amino acid metabolic process	GO:0006520	107	0.071
ribonucleoside metabolic process	GO:0009119	174	0.071
single organism catabolic process	GO:0044712	283	0.071
single organism reproductive process	GO:0044702	297	0.069
liver development	GO:0001889	90	0.069
drug metabolic process	GO:0017144	11	0.069
catabolic process	GO:0009056	351	0.067
small molecule biosynthetic process	GO:0044283	124	0.065
cellular response to endogenous stimulus	GO:0071495	377	0.064
cellular ketone metabolic process	GO:0042180	51	0.063
response to bacterium	GO:0009617	200	0.060
response to inorganic substance	GO:0010035	377	0.059
response to extracellular stimulus	GO:0009991	380	0.059
cellular lipid metabolic process	GO:0044255	208	0.057
epoxygenase p450 pathway	GO:0019373	1	0.056
gland development	GO:0048732	155	0.055
response to peptide	GO:1901652	292	0.055
organic acid biosynthetic process	GO:0016053	83	0.054
pteridine containing compound metabolic process	GO:0042558	14	0.053
multi organism reproductive process	GO:0044703	262	0.053
alpha amino acid metabolic process	GO:1901605	71	0.049
response to external biotic stimulus	GO:0043207	221	0.049
cellular response to glucocorticoid stimulus	GO:0071385	68	0.048
unsaturated fatty acid metabolic process	GO:0033559	39	0.047
single organism biosynthetic process	GO:0044711	342	0.046
response to acid chemical	GO:0001101	222	0.044
cellular response to lipid	GO:0071396	201	0.044
organic hydroxy compound biosynthetic process	GO:1901617	51	0.044
neutral lipid metabolic process	GO:0006638	21	0.043
response to cesium ion	GO:0010164	2	0.043
oxidation reduction process	GO:0055114	304	0.041
response to transition metal nanoparticle	GO:1990267	122	0.041
triglyceride metabolic process	GO:0006641	21	0.041
carboxylic acid biosynthetic process	GO:0046394	83	0.040
reproductive process	GO:0022414	372	0.040
benzene containing compound metabolic process	GO:0042537	22	0.039
organic cyclic compound catabolic process	GO:1901361	175	0.038
female pregnancy	GO:0007565	122	0.038
aging	GO:0007568	241	0.038
regulation of neuron differentiation	GO:0045664	208	0.038
acylglycerol metabolic process	GO:0006639	21	0.038
biphenyl metabolic process	GO:0018879	10	0.037
secondary metabolic process	GO:0019748	15	0.037
vitamin d3 metabolic process	GO:0070640	2	0.037
response to growth factor	GO:0070848	189	0.036
isoprenoid metabolic process	GO:0006720	45	0.036
heterocycle catabolic process	GO:0046700	167	0.035
response to herbicide	GO:0009635	16	0.035
lauric acid metabolic process	GO:0048252	4	0.035
response to reactive oxygen species	GO:0000302	120	0.034
response to lipopolysaccharide	GO:0032496	191	0.034
terpenoid metabolic process	GO:0006721	37	0.034
glycosyl compound metabolic process	GO:1901657	182	0.034
nucleoside phosphate metabolic process	GO:0006753	283	0.033
xenobiotic metabolic process	GO:0006805	19	0.033
organonitrogen compound catabolic process	GO:1901565	179	0.032
nucleotide metabolic process	GO:0009117	279	0.031
cellular response to peptide hormone stimulus	GO:0071375	120	0.031
response to oxidative stress	GO:0006979	186	0.031
response to testosterone	GO:0033574	55	0.031
nucleobase containing small molecule metabolic process	GO:0055086	316	0.031
developmental process involved in reproduction	GO:0003006	159	0.030
nucleobase containing compound catabolic process	GO:0034655	152	0.030
purine nucleoside metabolic process	GO:0042278	169	0.029
steroid biosynthetic process	GO:0006694	48	0.029
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.029
phenylpropanoid catabolic process	GO:0046271	3	0.029
cellular nitrogen compound catabolic process	GO:0044270	163	0.029
response to ionizing radiation	GO:0010212	59	0.029
regulation of cellular amine metabolic process	GO:0033238	8	0.028
steroid metabolic process	GO:0008202	73	0.028
nucleoside metabolic process	GO:0009116	179	0.028
coumarin catabolic process	GO:0046226	3	0.028
purine nucleotide catabolic process	GO:0006195	136	0.028
pyridine containing compound metabolic process	GO:0072524	32	0.028
regulation of cellular amino acid metabolic process	GO:0006521	2	0.028
steroid catabolic process	GO:0006706	5	0.027
response to cadmium ion	GO:0046686	35	0.027
organophosphate metabolic process	GO:0019637	370	0.027
phenol containing compound metabolic process	GO:0018958	30	0.027
response to glucocorticoid	GO:0051384	223	0.026
purine ribonucleotide metabolic process	GO:0009150	227	0.026
ribonucleotide catabolic process	GO:0009261	136	0.026
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.026
cellular response to steroid hormone stimulus	GO:0071383	93	0.026
cellular response to corticosteroid stimulus	GO:0071384	69	0.026
regulation of hormone levels	GO:0010817	187	0.026
cellular response to hormone stimulus	GO:0032870	247	0.026
regulation of programmed cell death	GO:0043067	341	0.026
peptidyl tyrosine phosphorylation	GO:0018108	72	0.026
ribonucleoside catabolic process	GO:0042454	126	0.025
carbohydrate derivative catabolic process	GO:1901136	147	0.024
response to vitamin	GO:0033273	131	0.024
regulation of apoptotic process	GO:0042981	335	0.023
ribonucleotide metabolic process	GO:0009259	231	0.023
response to temperature stimulus	GO:0009266	94	0.023
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.023
response to corticosteroid	GO:0031960	235	0.023
regulation of molecular function	GO:0065009	398	0.023
female gonad development	GO:0008585	53	0.022
cellular response to alcohol	GO:0097306	87	0.022
neuron development	GO:0048666	286	0.022
dopamine metabolic process	GO:0042417	12	0.022
response to ethanol	GO:0045471	162	0.022
nucleoside triphosphate metabolic process	GO:0009141	144	0.022
nucleoside triphosphate catabolic process	GO:0009143	123	0.022
organic hydroxy compound metabolic process	GO:1901615	115	0.021
phenylpropanoid metabolic process	GO:0009698	5	0.021
aromatic compound catabolic process	GO:0019439	168	0.021
response to insulin	GO:0032868	133	0.021
anatomical structure morphogenesis	GO:0009653	298	0.021
regulation of protein phosphorylation	GO:0001932	183	0.021
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.021
ribose phosphate metabolic process	GO:0019693	235	0.021
nucleotide catabolic process	GO:0009166	139	0.021
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.020
lipid biosynthetic process	GO:0008610	128	0.020
regulation of cellular ketone metabolic process	GO:0010565	27	0.020
purine ribonucleotide catabolic process	GO:0009154	136	0.020
cellular response to oxygen containing compound	GO:1901701	386	0.020
intracellular signal transduction	GO:0035556	314	0.019
regulation of neuron projection development	GO:0010975	161	0.019
reproductive structure development	GO:0048608	128	0.019
cellular amine metabolic process	GO:0044106	38	0.019
purine ribonucleoside catabolic process	GO:0046130	124	0.019
regulation of anatomical structure size	GO:0090066	135	0.019
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.019
regulation of cellular protein metabolic process	GO:0032268	267	0.019
purine nucleoside catabolic process	GO:0006152	124	0.019
amine metabolic process	GO:0009308	38	0.019
cellular component assembly	GO:0022607	360	0.018
response to toxic substance	GO:0009636	133	0.018
purine nucleotide metabolic process	GO:0006163	229	0.018
ras protein signal transduction	GO:0007265	29	0.018
response to monosaccharide	GO:0034284	159	0.018
multicellular organism reproduction	GO:0032504	233	0.018
peptidyl tyrosine modification	GO:0018212	72	0.018
transmission of nerve impulse	GO:0019226	42	0.018
xenobiotic catabolic process	GO:0042178	7	0.018
ion homeostasis	GO:0050801	212	0.018
protein phosphorylation	GO:0006468	345	0.018
regulation of cell differentiation	GO:0045595	320	0.018
homeostatic process	GO:0042592	331	0.018
cellular response to peptide	GO:1901653	133	0.018
vitamin d metabolic process	GO:0042359	4	0.018
regulation of phosphate metabolic process	GO:0019220	349	0.017
cellular response to cytokine stimulus	GO:0071345	127	0.017
response to radiation	GO:0009314	137	0.017
nucleoside catabolic process	GO:0009164	126	0.017
purine containing compound catabolic process	GO:0072523	138	0.017
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.017
apoptotic process	GO:0006915	381	0.017
carboxylic acid catabolic process	GO:0046395	49	0.016
behavior	GO:0007610	205	0.016
central nervous system development	GO:0007417	311	0.016
multicellular organismal reproductive process	GO:0048609	233	0.016
protein processing	GO:0016485	68	0.016
cellular chemical homeostasis	GO:0055082	247	0.016
reproductive system development	GO:0061458	128	0.016
response to vitamin e	GO:0033197	24	0.016
rhythmic process	GO:0048511	156	0.016
hormone metabolic process	GO:0042445	69	0.016
purine containing compound metabolic process	GO:0072521	253	0.016
cellular response to organic cyclic compound	GO:0071407	202	0.016
regulation of cell projection organization	GO:0031344	175	0.016
glycosyl compound catabolic process	GO:1901658	126	0.016
small gtpase mediated signal transduction	GO:0007264	36	0.016
cellular ion homeostasis	GO:0006873	184	0.016
epithelium development	GO:0060429	96	0.015
neuron differentiation	GO:0030182	368	0.015
androgen biosynthetic process	GO:0006702	10	0.015
cellular response to testosterone stimulus	GO:0071394	5	0.015
organelle organization	GO:0006996	266	0.015
response to biotic stimulus	GO:0009607	226	0.015
neuron fate commitment	GO:0048663	4	0.015
regulation of multicellular organismal development	GO:2000026	376	0.015
cellular response to external stimulus	GO:0071496	118	0.015
sexual reproduction	GO:0019953	148	0.014
organophosphate catabolic process	GO:0046434	148	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
lipid storage	GO:0019915	1	0.014
nucleoside phosphate catabolic process	GO:1901292	140	0.014
regulation of cell development	GO:0060284	263	0.014
regulation of cellular localization	GO:0060341	263	0.014
multicellular organismal signaling	GO:0035637	44	0.014
response to alkaloid	GO:0043279	132	0.014
cellular amino acid biosynthetic process	GO:0008652	32	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
regulation of blood circulation	GO:1903522	110	0.014
phenol containing compound biosynthetic process	GO:0046189	9	0.014
secondary alcohol metabolic process	GO:1902652	2	0.014
calcitriol biosynthetic process from calciol	GO:0036378	2	0.014
neuronal action potential	GO:0019228	35	0.014
organ regeneration	GO:0031100	101	0.014
multi multicellular organism process	GO:0044706	138	0.014
positive regulation of protein metabolic process	GO:0051247	178	0.013
action potential	GO:0001508	54	0.013
neuron projection development	GO:0031175	273	0.013
hormone catabolic process	GO:0042447	2	0.013
sensory perception	GO:0007600	101	0.013
heart morphogenesis	GO:0003007	3	0.013
icosanoid biosynthetic process	GO:0046456	18	0.013
insecticide metabolic process	GO:0017143	4	0.013
response to insecticide	GO:0017085	21	0.013
regulation of cellular component organization	GO:0051128	368	0.013
organic acid transport	GO:0015849	116	0.013
growth	GO:0040007	165	0.013
reproduction	GO:0000003	245	0.013
glycerolipid metabolic process	GO:0046486	67	0.013
glycoside transport	GO:1901656	2	0.013
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.013
purine ribonucleoside metabolic process	GO:0046128	168	0.013
positive regulation of neuron differentiation	GO:0045666	126	0.013
vascular process in circulatory system	GO:0003018	96	0.013
negative regulation of cell death	GO:0060548	229	0.013
regulation of neurogenesis	GO:0050767	247	0.012
organic substance catabolic process	GO:1901575	316	0.012
fluorene metabolic process	GO:0018917	1	0.012
synaptic growth at neuromuscular junction	GO:0051124	1	0.012
small molecule catabolic process	GO:0044282	59	0.012
neurological system process	GO:0050877	219	0.012
regulation of membrane potential	GO:0042391	110	0.012
regulation of blood pressure	GO:0008217	83	0.012
macromolecule localization	GO:0033036	252	0.012
chromosome segregation	GO:0007059	2	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.012
regulation of intracellular signal transduction	GO:1902531	218	0.012
brain development	GO:0007420	247	0.012
regulation of nucleotide catabolic process	GO:0030811	65	0.012
response to decreased oxygen levels	GO:0036293	237	0.012
cellular component biogenesis	GO:0044085	368	0.012
cellular response to growth factor stimulus	GO:0071363	162	0.012
negative regulation of metabolic process	GO:0009892	331	0.012
response to mercury ion	GO:0046689	15	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.012
programmed cell death	GO:0012501	392	0.012
negative regulation of cell cycle phase transition	GO:1901988	4	0.012
glial cell differentiation	GO:0010001	65	0.011
response to carbohydrate	GO:0009743	183	0.011
negative regulation of transport	GO:0051051	136	0.011
regulation of protein modification process	GO:0031399	194	0.011
negative regulation of programmed cell death	GO:0043069	183	0.011
positive regulation of cell projection organization	GO:0031346	111	0.011
cellular response to ethanol	GO:0071361	13	0.011
positive regulation of cellular biosynthetic process	GO:0031328	295	0.011
artery smooth muscle contraction	GO:0014824	4	0.011
neuron projection morphogenesis	GO:0048812	122	0.011
positive regulation of response to stimulus	GO:0048584	285	0.011
head development	GO:0060322	247	0.011
positive regulation of cell communication	GO:0010647	271	0.011
guanosine containing compound metabolic process	GO:1901068	74	0.011
guanosine containing compound catabolic process	GO:1901069	71	0.011
regulation of protein metabolic process	GO:0051246	289	0.011
diterpenoid metabolic process	GO:0016101	33	0.011
dendrite development	GO:0016358	72	0.011
negative regulation of apoptotic process	GO:0043066	181	0.011
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.011
reactive nitrogen species metabolic process	GO:2001057	1	0.011
sex differentiation	GO:0007548	113	0.011
regulation of catalytic activity	GO:0050790	304	0.011
regulation of nervous system development	GO:0051960	264	0.011
organic anion transport	GO:0015711	132	0.011
cellular response to extracellular stimulus	GO:0031668	73	0.011
gtp catabolic process	GO:0006184	71	0.010
nucleoside monophosphate metabolic process	GO:0009123	93	0.010
circulatory system process	GO:0003013	183	0.010
negative regulation of gene expression	GO:0010629	199	0.010
male gamete generation	GO:0048232	99	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	3	0.010
axis specification	GO:0009798	4	0.010
rna localization	GO:0006403	4	0.010
carbohydrate derivative metabolic process	GO:1901135	346	0.010
rho protein signal transduction	GO:0007266	11	0.010
acute inflammatory response	GO:0002526	58	0.010
regulation of proteolysis	GO:0030162	66	0.010
regulation of protein localization	GO:0032880	81	0.010
response to cytokine	GO:0034097	215	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.010

LOC100365112 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.023
disease of anatomical entity	DOID:7	0.023
sensory system disease	DOID:0050155	0.014
cardiovascular system disease	DOID:1287	0.012

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