Rattus norvegicus

124 known processes

Lepr

leptin receptor

(Aliases: Fa)

Lepr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to cytokineGO:00340972150.672
regulation of signal transductionGO:00099663180.648
response to lipopolysaccharideGO:00324961910.611
response to other organismGO:00517072200.586
wound healingGO:00420601220.547
cellular response to endogenous stimulusGO:00714953770.518
protein complex biogenesisGO:00702712630.505
positive regulation of cell communicationGO:00106472710.493
response to biotic stimulusGO:00096072260.429
response to campGO:0051591910.417
regulation of cellular protein metabolic processGO:00322682670.413
macromolecular complex assemblyGO:00650032730.405
response to estradiolGO:00323551640.391
response to woundingGO:00096112540.387
cellular response to lipidGO:00713962010.382
intracellular signal transductionGO:00355563140.376
protein complex subunit organizationGO:00718223020.376
modified amino acid transportGO:0072337120.351
inflammatory responseGO:00069541500.345
cellular response to oxygen containing compoundGO:19017013860.344
regulation of programmed cell deathGO:00430673410.342
regulation of apoptotic processGO:00429813350.337
regulation of cell proliferationGO:00421273590.336
response to molecule of bacterial originGO:00022371940.335
regulation of neutrophil migrationGO:190262260.332
cellular response to hormone stimulusGO:00328702470.314
epithelial cell proliferationGO:0050673540.297
positive regulation of signal transductionGO:00099671750.277
oxoacid metabolic processGO:00434362900.276
sexual reproductionGO:00199531480.270
regulation of phosphorylationGO:00423252480.268
positive regulation of molecular functionGO:00440932300.266
cellular response to organic cyclic compoundGO:00714072020.262
multi multicellular organism processGO:00447061380.259
protein complex assemblyGO:00064612630.252
programmed cell deathGO:00125013920.250
nucleic acid templated transcriptionGO:00976593790.248
reproductive processGO:00224143720.247
reproductionGO:00000032450.236
transcription from rna polymerase ii promoterGO:00063662520.235
response to estrogenGO:00436272320.232
response to external biotic stimulusGO:00432072210.221
regulation of intracellular signal transductionGO:19025312180.220
central nervous system developmentGO:00074173110.215
positive regulation of mapk cascadeGO:0043410920.214
response to bacteriumGO:00096172000.213
peptidyl tyrosine phosphorylationGO:0018108720.208
response to corticosteroidGO:00319602350.205
carboxylic acid metabolic processGO:00197522890.201
response to glucocorticoidGO:00513842230.201
cellular component assemblyGO:00226073600.195
macromolecule localizationGO:00330362520.188
response to organophosphorusGO:00466831020.187
positive regulation of cell deathGO:00109421840.186
positive regulation of response to stimulusGO:00485842850.183
secretionGO:00469033070.181
neuron differentiationGO:00301823680.176
response to nutrient levelsGO:00316673700.172
response to purine containing compoundGO:00140741260.170
response to oxygen levelsGO:00704822650.168
regulation of anatomical structure sizeGO:00900661350.164
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.163
gland developmentGO:00487321550.161
regulation of multicellular organismal developmentGO:20000263760.160
organ morphogenesisGO:0009887750.156
behaviorGO:00076102050.156
agingGO:00075682410.153
tissue developmentGO:00098882520.153
apoptotic processGO:00069153810.152
cellular response to steroid hormone stimulusGO:0071383930.152
response to ketoneGO:19016541820.150
organic acid metabolic processGO:00060822920.149
purinergic receptor signaling pathwayGO:0035587100.148
cell migrationGO:00164771970.148
cellular component movementGO:00069282480.146
tube developmentGO:0035295890.144
regulation of transcription dna templatedGO:00063553740.140
negative regulation of macromolecule metabolic processGO:00106052600.139
positive regulation of biosynthetic processGO:00098913190.138
cellular response to abiotic stimulusGO:0071214850.138
regulation of secretionGO:00510462240.137
regulation of hormone levelsGO:00108171870.136
single organism reproductive processGO:00447022970.135
regulation of molecular functionGO:00650093980.135
multicellular organism reproductionGO:00325042330.133
blood circulationGO:00080151830.132
regulation of phosphate metabolic processGO:00192203490.132
positive regulation of signalingGO:00230562700.130
regulation of tube sizeGO:0035150890.128
cell type specific apoptotic processGO:00972851340.128
negative regulation of cellular metabolic processGO:00313242810.128
response to nutrientGO:00075842480.128
negative regulation of apoptotic processGO:00430661810.127
anatomical structure formation involved in morphogenesisGO:0048646830.127
regulation of anatomical structure morphogenesisGO:00226031410.126
positive regulation of immune system processGO:0002684900.124
positive regulation of intracellular signal transductionGO:19025331380.122
organic acid transportGO:00158491160.122
positive regulation of phosphate metabolic processGO:00459372620.122
positive regulation of developmental processGO:00510942830.121
cell cell signalingGO:00072673350.121
positive regulation of apoptotic processGO:00430651540.120
peptidyl tyrosine modificationGO:0018212720.119
positive regulation of phosphorylationGO:00423271770.117
regulation of kinase activityGO:00435491170.116
regulation of epithelial cell proliferationGO:0050678490.115
negative regulation of cell proliferationGO:00082851190.114
regulation of cell differentiationGO:00455953200.113
regulation of phosphorus metabolic processGO:00511743490.113
regulation of protein metabolic processGO:00512462890.110
regulation of catalytic activityGO:00507903040.110
positive regulation of protein serine threonine kinase activityGO:0071902520.110
positive regulation of protein kinase activityGO:0045860730.109
multi organism reproductive processGO:00447032620.107
sensory perception of painGO:0019233730.107
multicellular organismal reproductive processGO:00486092330.107
organic anion transportGO:00157111320.107
regulation of transferase activityGO:00513381230.106
regulation of lipid biosynthetic processGO:0046890380.105
positive regulation of secretionGO:00510471400.104
protein transportGO:00150311320.103
positive regulation of cell proliferationGO:00082842490.102
locomotionGO:00400112370.102
regulation of exocytosisGO:0017157370.101
regulation of immune system processGO:00026821230.100
ion transmembrane transportGO:00342203650.099
positive regulation of cellular biosynthetic processGO:00313282950.098
neural crest cell differentiationGO:001403320.098
cytokine productionGO:0001816610.098
positive regulation of multicellular organismal processGO:00512403870.097
regulation of protein modification processGO:00313991940.096
neurological system processGO:00508772190.095
regenerationGO:00310991630.094
positive regulation of programmed cell deathGO:00430681570.094
localization of cellGO:00516742020.093
choline transportGO:001587140.092
regulation of rna biosynthetic processGO:20011413810.091
nitrogen compound transportGO:00717052290.091
regulation of protein phosphorylationGO:00019321830.090
sensory perceptionGO:00076001010.090
transmembrane transportGO:00550854120.090
pyruvate metabolic processGO:0006090270.090
secretion by cellGO:00329402480.089
head developmentGO:00603222470.089
regulation of rna metabolic processGO:00512523910.088
response to decreased oxygen levelsGO:00362932370.088
neural crest cell migrationGO:000175510.087
regulation of leukocyte migrationGO:0002685240.087
developmental process involved in reproductionGO:00030061590.087
ovulation cycle processGO:0022602500.086
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.086
positive regulation of phosphorus metabolic processGO:00105622620.083
protein oligomerizationGO:00512591910.083
positive regulation of protein phosphorylationGO:00019341350.083
cell part morphogenesisGO:00329901230.082
neuron projection morphogenesisGO:00488121220.082
angiogenesisGO:0001525530.082
cellular response to alcoholGO:0097306870.081
defense responseGO:00069521940.080
neuron deathGO:00709971270.079
leukocyte migrationGO:0050900380.079
response to radiationGO:00093141370.079
regulation of blood vessel sizeGO:0050880890.079
kidney developmentGO:0001822670.078
transcription dna templatedGO:00063513770.078
immune system processGO:00023762040.077
positive regulation of protein metabolic processGO:00512471780.077
protein homooligomerizationGO:0051260910.076
response to vitaminGO:00332731310.076
regulation of growthGO:00400081050.075
single organism biosynthetic processGO:00447113420.075
gliogenesisGO:0042063930.073
embryonic hindlimb morphogenesisGO:003511620.073
developmental growthGO:00485891000.073
gonad developmentGO:00084061040.073
respiratory system developmentGO:0060541450.073
development of primary female sexual characteristicsGO:0046545560.071
neuron developmentGO:00486662860.071
response to peptide hormoneGO:00434342780.070
response to mechanical stimulusGO:00096121340.070
response to extracellular stimulusGO:00099913800.069
ovulation cycleGO:0042698670.069
regulation of neuron apoptotic processGO:0043523830.069
neuron projection developmentGO:00311752730.069
regulation of cellular localizationGO:00603412630.068
rna metabolic processGO:00160704060.068
regulation of cellular ketone metabolic processGO:0010565270.068
macromolecular complex subunit organizationGO:00439333390.068
positive regulation of neuron apoptotic processGO:0043525330.068
regulation of cellular component organizationGO:00511283680.067
positive regulation of lipid biosynthetic processGO:0046889250.067
taxisGO:0042330670.067
regulation of endothelial cell apoptotic processGO:200035130.065
negative regulation of signalingGO:00230571570.065
cellular component biogenesisGO:00440853680.065
regulation of ossificationGO:0030278320.064
positive regulation of catalytic activityGO:00430851840.064
epithelium developmentGO:0060429960.064
hormone transportGO:00099141210.063
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.063
regulation of protein kinase activityGO:00458591050.063
negative regulation of cell deathGO:00605482290.061
cellular amino acid metabolic processGO:00065201070.061
neural crest cell developmentGO:001403220.061
regulation of calcium ion transportGO:0051924770.061
interleukin 18 productionGO:003262110.060
steroid biosynthetic processGO:0006694480.060
cellular response to organonitrogen compoundGO:00714171970.059
cation transportGO:00068123820.059
female sex differentiationGO:0046660590.059
mapk cascadeGO:00001651400.058
cellular response to peptide hormone stimulusGO:00713751200.057
regulation of leukocyte activationGO:0002694450.057
amino acid transportGO:0006865700.056
blood vessel developmentGO:0001568690.056
positive regulation of cellular protein metabolic processGO:00322701670.056
signal transduction by phosphorylationGO:00230141440.055
negative regulation of metabolic processGO:00098923310.054
positive regulation of nitrogen compound metabolic processGO:00511733340.054
response to hypoxiaGO:00016662310.053
striated muscle tissue developmentGO:0014706580.053
positive regulation of rna biosynthetic processGO:19026801970.053
regulation of secretion by cellGO:19035302080.053
calcium ion transportGO:00068161310.053
positive regulation of secretion by cellGO:19035321280.052
response to peptideGO:19016522920.052
cell chemotaxisGO:0060326310.051
anatomical structure morphogenesisGO:00096532980.051
positive regulation of transcription dna templatedGO:00458931970.051
renal system developmentGO:0072001670.051
cell activationGO:0001775970.050
positive regulation of neuron deathGO:1901216430.050
negative regulation of signal transductionGO:0009968830.050
peptidyl amino acid modificationGO:00181931260.049
positive regulation of kinase activityGO:0033674770.049
regulation of neurotransmitter levelsGO:0001505420.049
response to inorganic substanceGO:00100353770.048
response to toxic substanceGO:00096361330.048
divalent metal ion transportGO:00708381320.048
response to metal ionGO:00100382530.047
reproductive system developmentGO:00614581280.047
erk1 and erk2 cascadeGO:0070371480.047
cytokine mediated signaling pathwayGO:0019221430.047
regulation of transcription from rna polymerase ii promoterGO:00063572340.046
antibiotic transportGO:004289120.046
cellular response to corticosteroid stimulusGO:0071384690.046
negative regulation of nucleic acid templated transcriptionGO:19035071170.046
leukocyte homeostasisGO:000177670.046
negative regulation of gene expressionGO:00106291990.045
anterior posterior pattern specificationGO:000995210.045
positive regulation of growthGO:0045927550.045
leukocyte cell cell adhesionGO:000715940.045
hormone metabolic processGO:0042445690.044
regulation of homeostatic processGO:00328441010.044
norepinephrine transportGO:0015874180.044
positive regulation of rna metabolic processGO:00512542030.043
positive regulation of interleukin 18 productionGO:003274110.043
female pregnancyGO:00075651220.043
maintenance of locationGO:0051235170.043
response to anoxiaGO:003405940.042
circulatory system processGO:00030131830.042
development of primary sexual characteristicsGO:00451371070.042
negative regulation of programmed cell deathGO:00430691830.042
organic substance catabolic processGO:19015753160.042
regulation of neurogenesisGO:00507672470.042
cellular response to glucocorticoid stimulusGO:0071385680.042
rna biosynthetic processGO:00327743800.042
response to interleukin 1GO:0070555550.041
vasoconstrictionGO:0042310540.041
monocarboxylic acid transportGO:0015718520.040
cellular catabolic processGO:00442482950.040
t cell costimulationGO:003129520.040
muscle tissue developmentGO:0060537580.040
negative regulation of response to stimulusGO:00485851550.040
reactive oxygen species metabolic processGO:0072593370.040
regulation of cellular amino acid metabolic processGO:000652120.040
regulation of cell cycleGO:0051726730.039
blood vessel morphogenesisGO:0048514580.039
regulation of system processGO:00440572080.039
diencephalon developmentGO:0021536210.039
gamete generationGO:00072761240.039
lung developmentGO:0030324430.039
female gonad developmentGO:0008585530.039
rhythmic processGO:00485111560.038
negative regulation of cellular protein metabolic processGO:00322691060.038
negative regulation of transportGO:00510511360.038
protein phosphorylationGO:00064683450.038
regulation of defecationGO:200029210.038
myeloid leukocyte migrationGO:0097529200.037
cellular response to mechanical stimulusGO:0071260480.037
response to growth factorGO:00708481890.037
regulation of norepinephrine secretionGO:0014061150.037
cell projection organizationGO:00300303020.037
lipid biosynthetic processGO:00086101280.037
response to testosteroneGO:0033574550.037
brain developmentGO:00074202470.036
homeostatic processGO:00425923310.036
muscle structure developmentGO:0061061870.036
extrinsic apoptotic signaling pathwayGO:0097191100.036
cation transmembrane transportGO:00986552630.036
oligopeptide transportGO:000685740.036
amide transportGO:00428861050.036
growthGO:00400071650.036
appendage morphogenesisGO:003510740.036
cellular amine metabolic processGO:0044106380.035
regulation of nervous system developmentGO:00519602640.035
response to indole 3 methanolGO:007168020.035
positive regulation of protein modification processGO:00314011420.035
response to acid chemicalGO:00011012220.035
positive regulation of heterotypic cell cell adhesionGO:003411610.035
olfactory bulb interneuron differentiationGO:002188910.035
regulation of erk1 and erk2 cascadeGO:0070372410.035
response to retinoic acidGO:0032526630.035
negative regulation of cell differentiationGO:0045596990.035
muscle system processGO:00030121150.034
regulation of developmental growthGO:0048638450.034
immune responseGO:00069551040.034
axon developmentGO:0061564960.034
heat acclimationGO:001028610.033
negative regulation of nitrogen compound metabolic processGO:00511721610.033
tissue morphogenesisGO:0048729220.033
forebrain developmentGO:0030900980.033
cellular response to nitrogen compoundGO:19016992100.032
steroid metabolic processGO:0008202730.032
regulation of ion transportGO:00432692450.032
cellular response to lipopolysaccharideGO:0071222550.032
negative regulation of protein metabolic processGO:00512481140.032
single organism carbohydrate metabolic processGO:00447231180.032
cell motilityGO:00488702020.032
g protein coupled receptor signaling pathwayGO:00071862420.032
positive regulation of cytokine productionGO:0001819420.032
regulation of immunoglobulin productionGO:000263740.032
chemical homeostasisGO:00488782920.032
vasculature developmentGO:0001944700.031
cellular ketone metabolic processGO:0042180510.031
regulation of osteoblast differentiationGO:0045667140.031
vasodilationGO:0042311440.030
amine metabolic processGO:0009308380.030
response to alkaloidGO:00432791320.030
response to nicotineGO:0035094510.030
response to ethanolGO:00454711620.030
divalent inorganic cation transportGO:00725111340.030
single organism catabolic processGO:00447122830.030
negative regulation of osteoblast differentiationGO:004566820.030
signal releaseGO:00230611450.029
posttranscriptional regulation of gene expressionGO:0010608370.029
regulation of metal ion transportGO:00109591180.029
cerebral cortex tangential migrationGO:002180010.029
small molecule biosynthetic processGO:00442831240.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.029
reactive nitrogen species metabolic processGO:200105710.029
response to reactive oxygen speciesGO:00003021200.028
ameboidal type cell migrationGO:0001667260.028
cellular response to growth factor stimulusGO:00713631620.028
anion transportGO:00068201780.028
catabolic processGO:00090563510.028
cardiac ventricle developmentGO:000323110.028
positive regulation of transportGO:00510502450.028
single organism cellular localizationGO:19025801020.028
negative regulation of biosynthetic processGO:00098901680.028
regulation of nucleic acid templated transcriptionGO:19035063800.028
platelet aggregationGO:007052740.027
regulation of b cell proliferationGO:003088860.027
dicarboxylic acid transportGO:0006835340.027
regulation of protein heterodimerization activityGO:004349710.027
organic hydroxy compound metabolic processGO:19016151150.027
establishment of protein localizationGO:00451841410.027
positive regulation of cellular amino acid metabolic processGO:004576410.027
regulation of cell migrationGO:00303341280.027
ion homeostasisGO:00508012120.027
inorganic cation transmembrane transportGO:00986622020.027
cellular response to peptideGO:19016531330.027
positive regulation of cardiac muscle cell proliferationGO:006004540.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
catecholamine transportGO:0051937370.026
regulation of hydrolase activityGO:00513361430.026
urogenital system developmentGO:0001655780.026
cell cycleGO:00070491010.026
tissue regenerationGO:0042246360.026
carboxylic acid transportGO:00469421150.026
hematopoietic or lymphoid organ developmentGO:0048534360.026
vascular process in circulatory systemGO:0003018960.026
organic hydroxy compound transportGO:0015850770.026
single organismal cell cell adhesionGO:0016337420.026
alpha beta t cell activationGO:004663130.025
synaptic transmissionGO:00072682350.025
regulation of mapk cascadeGO:00434081160.025
positive regulation of immunoglobulin mediated immune responseGO:000289120.025
inorganic ion transmembrane transportGO:00986602290.025
axonogenesisGO:0007409710.025
receptor metabolic processGO:0043112180.025
cardiac muscle tissue growthGO:0055017200.024
organ formationGO:004864530.024
regulation of protein transportGO:0051223680.024
germ cell migrationGO:000835410.024
regulation of jak stat cascadeGO:0046425210.024
muscle cell proliferationGO:0033002840.024
positive regulation of lymphocyte proliferationGO:0050671200.024
cell morphogenesisGO:00009021420.024
negative regulation of calcium ion importGO:009028120.024
organ growthGO:0035265240.024
cell growthGO:00160491040.024
regulation of protein localizationGO:0032880810.024
positive regulation of lipid metabolic processGO:0045834330.024
signal transduction involved in regulation of gene expressionGO:002301940.023
organic hydroxy compound biosynthetic processGO:1901617510.023
skeletal muscle tissue developmentGO:0007519310.023
carbohydrate derivative metabolic processGO:19011353460.023
carbohydrate metabolic processGO:00059751300.023
positive regulation of map kinase activityGO:0043406460.023
regulation of ion homeostasisGO:2000021630.023
tissue remodelingGO:0048771400.023
t cell homeostasisGO:004302920.023
regulation of cell developmentGO:00602842630.023
muscle organ developmentGO:0007517500.023
organ regenerationGO:00311001010.023
small gtpase mediated signal transductionGO:0007264360.023
erythrocyte differentiationGO:003021810.023
positive regulation of epithelial cell proliferationGO:0050679320.022
cellular response to molecule of bacterial originGO:0071219560.022
regulation of sensory perceptionGO:0051931290.022
response to heatGO:0009408600.022
limb morphogenesisGO:003510840.022
positive regulation of humoral immune responseGO:000292220.022
response to fatty acidGO:0070542650.022
hormone secretionGO:00468791150.022
lymphocyte homeostasisGO:000226020.022
parturitionGO:0007567100.022
male sex differentiationGO:0046661640.022
biological adhesionGO:00226101100.022
hindlimb morphogenesisGO:003513720.022
g protein coupled purinergic nucleotide receptor signaling pathwayGO:003558930.022
regulation of establishment of protein localizationGO:0070201690.022
negative regulation of cell communicationGO:00106481580.022
liver developmentGO:0001889900.022
sulfur compound transportGO:007234880.021
positive regulation of transferase activityGO:0051347810.021
metal ion transportGO:00300012890.021
regulation of protein secretionGO:0050708280.021
cellular response to external stimulusGO:00714961180.021
enzyme linked receptor protein signaling pathwayGO:00071671160.021
reproductive structure developmentGO:00486081280.021
positive regulation of cell developmentGO:00107201760.021
regulation of cell morphogenesis involved in differentiationGO:0010769720.021
negative regulation of multicellular organismal processGO:00512412030.020
specification of organ identityGO:001009220.020
cerebral cortex cell migrationGO:002179540.020
endocrine system developmentGO:0035270300.020
endosomal lumen acidificationGO:004838810.020
lymphocyte activationGO:0046649430.020
regulation of cytokine productionGO:0001817560.020
endothelial cell apoptotic processGO:007257730.020
regulation of mononuclear cell proliferationGO:0032944260.020
regulation of cell activationGO:0050865500.020
negative regulation of developmental processGO:00510931250.020
activation of protein kinase activityGO:0032147470.020
osteoblast differentiationGO:0001649260.020
neuron apoptotic processGO:0051402880.020
insulin like growth factor receptor signaling pathwayGO:004800930.020
embryo developmentGO:0009790490.020
response to oxidative stressGO:00069791860.020
melanocyte differentiationGO:003031820.019
lipid storageGO:001991510.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
regulation of cell adhesionGO:0030155520.019
cellular response to interleukin 1GO:0071347370.019
hepaticobiliary system developmentGO:0061008900.019
positive regulation of inflammatory responseGO:0050729240.019
hair cycle processGO:002240520.019
regulation of response to external stimulusGO:00321011060.019
autonomic nervous system developmentGO:004848330.019
morphogenesis of an epitheliumGO:0002009200.019
cellular response to cytokine stimulusGO:00713451270.019
motor neuron axon guidanceGO:000804510.019
regulation of organ formationGO:000315620.019
positive regulation of protein transportGO:0051222410.019
respiratory tube developmentGO:0030323430.019
positive regulation of b cell mediated immunityGO:000271420.019
regulation of extrinsic apoptotic signaling pathwayGO:200123670.019
smooth muscle cell migrationGO:0014909360.019
positive regulation of neurogenesisGO:00507691650.018
calcium ion importGO:0070509220.018
positive regulation of cell activationGO:0050867340.018
cell differentiation in hindbrainGO:002153320.018
lung alveolus developmentGO:004828660.018
response to tumor necrosis factorGO:0034612560.018
cellular calcium ion homeostasisGO:00068741600.018
carbohydrate biosynthetic processGO:0016051420.018
hair cycleGO:004263330.018

Lepr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
nervous system diseaseDOID:86300.078
central nervous system diseaseDOID:33100.036
sensory system diseaseDOID:005015500.033
connective tissue diseaseDOID:6500.022
musculoskeletal system diseaseDOID:1700.022
immune system diseaseDOID:291400.021