| negative regulation of metabolic process | GO:0009892 | 331 | 0.251 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.205 | |
| negative regulation of apoptotic process | GO:0043066 | 181 | 0.199 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.195 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.188 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 260 | 0.179 | |
| regulation of molecular function | GO:0065009 | 398 | 0.172 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.160 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.158 | |
| reproductive process | GO:0022414 | 372 | 0.158 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.152 | |
| response to peptide hormone | GO:0043434 | 278 | 0.133 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.129 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.127 | |
| cellular response to peptide | GO:1901653 | 133 | 0.124 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.114 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 106 | 0.109 | |
| negative regulation of biosynthetic process | GO:0009890 | 168 | 0.108 | |
| response to peptide | GO:1901652 | 292 | 0.104 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.104 | |
| organelle organization | GO:0006996 | 266 | 0.102 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.099 | |
| single organism reproductive process | GO:0044702 | 297 | 0.099 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.095 | |
| mitotic spindle organization | GO:0007052 | 2 | 0.093 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 161 | 0.092 | |
| protein complex assembly | GO:0006461 | 263 | 0.090 | |
| negative regulation of programmed cell death | GO:0043069 | 183 | 0.089 | |
| cell cycle | GO:0007049 | 101 | 0.084 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.082 | |
| programmed cell death | GO:0012501 | 392 | 0.079 | |
| reproduction | GO:0000003 | 245 | 0.078 | |
| regulation of signal transduction | GO:0009966 | 318 | 0.076 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.075 | |
| insulin receptor signaling pathway | GO:0008286 | 24 | 0.073 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.070 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.070 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.069 | |
| rna metabolic process | GO:0016070 | 406 | 0.067 | |
| mitotic cell cycle | GO:0000278 | 49 | 0.067 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.066 | |
| mitotic cell cycle process | GO:1903047 | 35 | 0.066 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.064 | |
| negative regulation of cellular response to insulin stimulus | GO:1900077 | 11 | 0.061 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.059 | |
| response to temperature stimulus | GO:0009266 | 94 | 0.058 | |
| response to heat | GO:0009408 | 60 | 0.057 | |
| regulation of protein metabolic process | GO:0051246 | 289 | 0.057 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 141 | 0.054 | |
| transcription dna templated | GO:0006351 | 377 | 0.052 | |
| apoptotic process | GO:0006915 | 381 | 0.051 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.050 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.050 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.049 | |
| cell cell recognition | GO:0009988 | 1 | 0.046 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 116 | 0.046 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.046 | |
| negative regulation of protein metabolic process | GO:0051248 | 114 | 0.044 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 197 | 0.042 | |
| organ morphogenesis | GO:0009887 | 75 | 0.042 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.041 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.041 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.041 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.041 | |
| toxin transport | GO:1901998 | 3 | 0.040 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.040 | |
| cytoskeleton organization | GO:0007010 | 111 | 0.039 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.039 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.039 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.039 | |
| multicellular organism reproduction | GO:0032504 | 233 | 0.038 | |
| translation | GO:0006412 | 35 | 0.038 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.038 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.037 | |
| defense response | GO:0006952 | 194 | 0.036 | |
| regulation of cellular amine metabolic process | GO:0033238 | 8 | 0.036 | |
| response to oxygen levels | GO:0070482 | 265 | 0.036 | |
| cellular response to insulin stimulus | GO:0032869 | 81 | 0.036 | |
| cellular component assembly | GO:0022607 | 360 | 0.035 | |
| regulation of transforming growth factor beta3 production | GO:0032910 | 2 | 0.035 | |
| regulation of hydrolase activity | GO:0051336 | 143 | 0.034 | |
| positive regulation of transport | GO:0051050 | 245 | 0.033 | |
| protein maturation | GO:0051604 | 68 | 0.033 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.032 | |
| single organism intracellular transport | GO:1902582 | 166 | 0.032 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.032 | |
| negative regulation of insulin receptor signaling pathway | GO:0046627 | 10 | 0.032 | |
| chromosome segregation | GO:0007059 | 2 | 0.032 | |
| cellular response to stress | GO:0033554 | 269 | 0.031 | |
| sexual reproduction | GO:0019953 | 148 | 0.031 | |
| single fertilization | GO:0007338 | 3 | 0.031 | |
| proteolysis | GO:0006508 | 175 | 0.030 | |
| cell cycle g1 s phase transition | GO:0044843 | 13 | 0.030 | |
| cellular component morphogenesis | GO:0032989 | 155 | 0.030 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 295 | 0.030 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.030 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 247 | 0.030 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 161 | 0.029 | |
| cellular response to peptide hormone stimulus | GO:0071375 | 120 | 0.029 | |
| response to carbohydrate | GO:0009743 | 183 | 0.029 | |
| cellular catabolic process | GO:0044248 | 295 | 0.028 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.028 | |
| ion transmembrane transport | GO:0034220 | 365 | 0.028 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.028 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.028 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.027 | |
| chromatin assembly or disassembly | GO:0006333 | 1 | 0.027 | |
| purine nucleotide biosynthetic process | GO:0006164 | 83 | 0.027 | |
| smad protein complex assembly | GO:0007183 | 1 | 0.027 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 141 | 0.026 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.026 | |
| spindle organization | GO:0007051 | 2 | 0.026 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.026 | |
| peptidyl amino acid modification | GO:0018193 | 126 | 0.026 | |
| cellular response to hormone stimulus | GO:0032870 | 247 | 0.025 | |
| positive regulation of cellular component organization | GO:0051130 | 200 | 0.025 | |
| response to hypoxia | GO:0001666 | 231 | 0.024 | |
| regulation of immune response | GO:0050776 | 55 | 0.024 | |
| cell cycle phase transition | GO:0044770 | 21 | 0.024 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.023 | |
| neuron differentiation | GO:0030182 | 368 | 0.023 | |
| protein transport | GO:0015031 | 132 | 0.023 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.022 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.021 | |
| neuron development | GO:0048666 | 286 | 0.021 | |
| cell cycle checkpoint | GO:0000075 | 2 | 0.021 | |
| cation transmembrane transport | GO:0098655 | 263 | 0.021 | |
| response to cytokine | GO:0034097 | 215 | 0.020 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.020 | |
| synaptic transmission | GO:0007268 | 235 | 0.020 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.019 | |
| blood circulation | GO:0008015 | 183 | 0.019 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.019 | |
| response to other organism | GO:0051707 | 220 | 0.019 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.019 | |
| response to nutrient levels | GO:0031667 | 370 | 0.019 | |
| negative regulation of signaling | GO:0023057 | 157 | 0.019 | |
| regulation of cellular protein metabolic process | GO:0032268 | 267 | 0.019 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.018 | |
| single organism organelle organization | GO:1902589 | 180 | 0.018 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.018 | |
| purine containing compound biosynthetic process | GO:0072522 | 85 | 0.018 | |
| regulation of vesicle mediated transport | GO:0060627 | 81 | 0.018 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 3 | 0.018 | |
| regulation of cell cycle | GO:0051726 | 73 | 0.018 | |
| central nervous system development | GO:0007417 | 311 | 0.018 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.018 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 4 | 0.017 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.017 | |
| metal ion homeostasis | GO:0055065 | 186 | 0.017 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.017 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.017 | |
| cellular homeostasis | GO:0019725 | 252 | 0.017 | |
| cation transport | GO:0006812 | 382 | 0.017 | |
| protein oligomerization | GO:0051259 | 191 | 0.017 | |
| transforming growth factor beta3 production | GO:0032907 | 2 | 0.017 | |
| positive regulation of response to stimulus | GO:0048584 | 285 | 0.017 | |
| behavior | GO:0007610 | 205 | 0.016 | |
| response to glucose | GO:0009749 | 136 | 0.016 | |
| cellular response to organonitrogen compound | GO:0071417 | 197 | 0.016 | |
| response to corticosteroid | GO:0031960 | 235 | 0.016 | |
| response to growth factor | GO:0070848 | 189 | 0.016 | |
| vesicle mediated transport | GO:0016192 | 181 | 0.016 | |
| cellular protein complex assembly | GO:0043623 | 44 | 0.016 | |
| secretion | GO:0046903 | 307 | 0.016 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.016 | |
| response to estrogen | GO:0043627 | 232 | 0.016 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.016 | |
| positive regulation of cell projection organization | GO:0031346 | 111 | 0.016 | |
| gtp catabolic process | GO:0006184 | 71 | 0.015 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 2 | 0.015 | |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.015 | |
| regulation of cell development | GO:0060284 | 263 | 0.015 | |
| cellular protein catabolic process | GO:0044257 | 19 | 0.015 | |
| cell morphogenesis involved in neuron differentiation | GO:0048667 | 106 | 0.015 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.015 | |
| positive regulation of bone mineralization | GO:0030501 | 4 | 0.015 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.015 | |
| negative regulation of signal transduction | GO:0009968 | 83 | 0.015 | |
| tissue development | GO:0009888 | 252 | 0.015 | |
| response to nutrient | GO:0007584 | 248 | 0.015 | |
| neurological system process | GO:0050877 | 219 | 0.015 | |
| response to monosaccharide | GO:0034284 | 159 | 0.015 | |
| regulation of cellular response to insulin stimulus | GO:1900076 | 16 | 0.015 | |
| dna packaging | GO:0006323 | 4 | 0.015 | |
| response to external biotic stimulus | GO:0043207 | 221 | 0.015 | |
| mitotic dna damage checkpoint | GO:0044773 | 1 | 0.014 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 75 | 0.014 | |
| regulation of protein processing | GO:0070613 | 50 | 0.014 | |
| amine metabolic process | GO:0009308 | 38 | 0.014 | |
| negative regulation of proteolysis | GO:0045861 | 41 | 0.014 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.014 | |
| protein phosphorylation | GO:0006468 | 345 | 0.014 | |
| cell morphogenesis involved in differentiation | GO:0000904 | 119 | 0.014 | |
| cellular ketone metabolic process | GO:0042180 | 51 | 0.014 | |
| cell cycle process | GO:0022402 | 57 | 0.014 | |
| spermatogenesis | GO:0007283 | 99 | 0.014 | |
| dendrite development | GO:0016358 | 72 | 0.014 | |
| chromatin remodeling | GO:0006338 | 3 | 0.014 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.014 | |
| regulation of response to external stimulus | GO:0032101 | 106 | 0.014 | |
| wound healing | GO:0042060 | 122 | 0.014 | |
| gamete generation | GO:0007276 | 124 | 0.013 | |
| regulation of phosphorus metabolic process | GO:0051174 | 349 | 0.013 | |
| macromolecule catabolic process | GO:0009057 | 58 | 0.013 | |
| cell projection morphogenesis | GO:0048858 | 123 | 0.013 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.013 | |
| protein processing | GO:0016485 | 68 | 0.013 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 234 | 0.013 | |
| circulatory system process | GO:0003013 | 183 | 0.013 | |
| cellular macromolecular complex assembly | GO:0034622 | 58 | 0.013 | |
| establishment of protein localization | GO:0045184 | 141 | 0.013 | |
| male gamete generation | GO:0048232 | 99 | 0.013 | |
| golgi vesicle transport | GO:0048193 | 22 | 0.013 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 19 | 0.013 | |
| dephosphorylation | GO:0016311 | 98 | 0.013 | |
| development of primary sexual characteristics | GO:0045137 | 107 | 0.013 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.013 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.013 | |
| response to wounding | GO:0009611 | 254 | 0.013 | |
| neuron projection development | GO:0031175 | 273 | 0.012 | |
| nucleotide biosynthetic process | GO:0009165 | 98 | 0.012 | |
| inorganic ion transmembrane transport | GO:0098660 | 229 | 0.012 | |
| halogenated hydrocarbon metabolic process | GO:0042197 | 4 | 0.012 | |
| mitochondrion organization | GO:0007005 | 35 | 0.012 | |
| positive regulation of signal transduction | GO:0009967 | 175 | 0.012 | |
| muscle structure development | GO:0061061 | 87 | 0.012 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.012 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.012 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.012 | |
| regulation of protein modification process | GO:0031399 | 194 | 0.012 | |
| catabolic process | GO:0009056 | 351 | 0.012 | |
| regulation of transferase activity | GO:0051338 | 123 | 0.012 | |
| negative regulation of catalytic activity | GO:0043086 | 103 | 0.011 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 38 | 0.011 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 14 | 0.011 | |
| inflammatory response | GO:0006954 | 150 | 0.011 | |
| nucleosome organization | GO:0034728 | 1 | 0.011 | |
| muscle organ development | GO:0007517 | 50 | 0.011 | |
| cell part morphogenesis | GO:0032990 | 123 | 0.011 | |
| sex differentiation | GO:0007548 | 113 | 0.011 | |
| mapk cascade | GO:0000165 | 140 | 0.011 | |
| immune response | GO:0006955 | 104 | 0.011 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 11 | 0.011 | |
| positive regulation of protein metabolic process | GO:0051247 | 178 | 0.011 | |
| regulation of protein phosphorylation | GO:0001932 | 183 | 0.010 | |
| embryonic pattern specification | GO:0009880 | 1 | 0.010 | |
| developmental growth | GO:0048589 | 100 | 0.010 | |
| single organism catabolic process | GO:0044712 | 283 | 0.010 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 262 | 0.010 | |
| response to insulin | GO:0032868 | 133 | 0.010 | |
| cation homeostasis | GO:0055080 | 195 | 0.010 | |
| regulation of cellular localization | GO:0060341 | 263 | 0.010 | |
