Rattus norvegicus

28 known processes

Mip

major intrinsic protein of lens fiber

(Aliases: Aqp0)

Mip biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
camera type eye developmentGO:0043010480.484
Zebrafish Mouse
regulation of secretionGO:00510462240.248
eye developmentGO:0001654500.243
Zebrafish Mouse
sensory organ developmentGO:0007423740.220
Zebrafish Mouse
adenohypophysis developmentGO:002198420.197
tissue developmentGO:00098882520.185
regulation of molecular functionGO:00650093980.180
negative regulation of biosynthetic processGO:00098901680.176
macromolecule localizationGO:00330362520.171
cellular lipid metabolic processGO:00442552080.155
carboxylic acid metabolic processGO:00197522890.146
organic acid metabolic processGO:00060822920.139
inorganic ion transmembrane transportGO:00986602290.138
dorsal ventral axon guidanceGO:003356310.133
cellular response to organic cyclic compoundGO:00714072020.132
Rat
regulation of transcription dna templatedGO:00063553740.131
response to alkaloidGO:00432791320.123
regulation of cellular localizationGO:00603412630.120
oxoacid metabolic processGO:00434362900.119
rna metabolic processGO:00160704060.118
transmembrane transportGO:00550854120.110
neuron differentiationGO:00301823680.110
forebrain developmentGO:0030900980.108
Rat
rna biosynthetic processGO:00327743800.106
agingGO:00075682410.105
Rat
eye morphogenesisGO:004859240.101
inorganic cation transmembrane transportGO:00986622020.100
regulation of rna metabolic processGO:00512523910.097
anatomical structure morphogenesisGO:00096532980.097
Yeast
neurological system processGO:00508772190.096
Mouse
lens development in camera type eyeGO:0002088130.094
Zebrafish Mouse
nucleic acid templated transcriptionGO:00976593790.093
purine nucleotide metabolic processGO:00061632290.092
regulation of locomotionGO:00400121480.092
Rat
transcription dna templatedGO:00063513770.089
ion transmembrane transportGO:00342203650.087
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.087
chemical homeostasisGO:00488782920.086
Rat
regulation of rna biosynthetic processGO:20011413810.084
cellular response to endogenous stimulusGO:00714953770.084
Rat
reproductive processGO:00224143720.084
Yeast Rat
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.084
secretionGO:00469033070.082
ribonucleotide metabolic processGO:00092592310.080
positive regulation of nucleobase containing compound metabolic processGO:00459353190.075
protein transportGO:00150311320.074
carbohydrate derivative metabolic processGO:19011353460.074
protein localizationGO:00081041910.072
lipid metabolic processGO:00066292830.068
gland developmentGO:00487321550.067
positive regulation of transcription dna templatedGO:00458931970.067
regulation of secretion by cellGO:19035302080.067
negative regulation of cell deathGO:00605482290.067
cation transmembrane transportGO:00986552630.064
cellular component movementGO:00069282480.063
Rat
negative regulation of rna biosynthetic processGO:19026791180.062
intracellular transportGO:00469071850.061
negative regulation of cellular biosynthetic processGO:00313271610.060
positive regulation of gene expressionGO:00106282440.060
programmed cell deathGO:00125013920.060
Rat
cation transportGO:00068123820.060
Rat
divalent metal ion transportGO:00708381320.060
Rat
regulation of protein transportGO:0051223680.059
regulation of ion transportGO:00432692450.058
Rat
heart morphogenesisGO:000300730.058
negative regulation of nucleic acid templated transcriptionGO:19035071170.058
negative regulation of cellular metabolic processGO:00313242810.058
positive regulation of phosphorus metabolic processGO:00105622620.057
central nervous system developmentGO:00074173110.056
Rat
nicotine metabolic processGO:001893310.056
metal ion transportGO:00300012890.056
Rat
transcription from rna polymerase ii promoterGO:00063662520.056
apoptotic processGO:00069153810.055
Rat
response to peptide hormoneGO:00434342780.055
Rat
nucleobase containing small molecule metabolic processGO:00550863160.055
retina development in camera type eyeGO:0060041270.055
homeostatic processGO:00425923310.054
Rat
nucleoside phosphate biosynthetic processGO:19012931020.054
purine nucleotide biosynthetic processGO:0006164830.054
regulation of nucleic acid templated transcriptionGO:19035063800.053
ribose phosphate metabolic processGO:00196932350.052
negative regulation of metabolic processGO:00098923310.052
purine ribonucleotide metabolic processGO:00091502270.051
peptide secretionGO:0002790860.051
positive regulation of nitrogen compound metabolic processGO:00511733340.051
positive regulation of nucleic acid templated transcriptionGO:19035081970.050
negative regulation of macromolecule metabolic processGO:00106052600.049
negative regulation of nucleobase containing compound metabolic processGO:00459341530.049
regulation of hydrolase activityGO:00513361430.048
positive regulation of phosphate metabolic processGO:00459372620.048
secretion by cellGO:00329402480.048
negative regulation of macromolecule biosynthetic processGO:00105581480.045
negative regulation of apoptotic processGO:00430661810.045
startle responseGO:000196420.044
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.044
macromolecular complex assemblyGO:00650032730.044
Rat
divalent inorganic cation transportGO:00725111340.044
Rat
regulation of programmed cell deathGO:00430673410.043
regulation of cellular amino acid metabolic processGO:000652120.043
positive regulation of rna metabolic processGO:00512542030.042
regulation of protein localizationGO:0032880810.042
cellular catabolic processGO:00442482950.041
neuron developmentGO:00486662860.041
response to nutrientGO:00075842480.041
odontogenesisGO:0042476320.040
negative regulation of signal transductionGO:0009968830.040
cellular amine metabolic processGO:0044106380.040
brain developmentGO:00074202470.040
Rat
regulation of transcription from rna polymerase ii promoterGO:00063572340.039
regulation of apoptotic processGO:00429813350.039
hormone transportGO:00099141210.039
cellular response to lipidGO:00713962010.039
Rat
organic hydroxy compound metabolic processGO:19016151150.039
response to glucocorticoidGO:00513842230.037
Rat
nucleotide metabolic processGO:00091172790.037
positive regulation of molecular functionGO:00440932300.036
cellular response to oxygen containing compoundGO:19017013860.036
Rat
organophosphate metabolic processGO:00196373700.036
development of primary sexual characteristicsGO:00451371070.036
response to inorganic substanceGO:00100353770.035
Rat
multi organism reproductive processGO:00447032620.035
Yeast Rat
organic substance catabolic processGO:19015753160.035
response to extracellular stimulusGO:00099913800.035
Rat
response to corticosteroidGO:00319602350.035
Rat
urogenital system developmentGO:0001655780.034
protein complex biogenesisGO:00702712630.034
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.034
regulation of hormone secretionGO:00468831060.034
response to nutrient levelsGO:00316673700.034
Rat
monocarboxylic acid metabolic processGO:00327871520.033
epithelium developmentGO:0060429960.033
cell motilityGO:00488702020.033
Rat
negative regulation of programmed cell deathGO:00430691830.032
regulation of establishment of protein localizationGO:0070201690.032
chemotaxisGO:0006935660.032
response to oxygen levelsGO:00704822650.032
regulation of purine nucleotide metabolic processGO:19005421150.031
protein phosphorylationGO:00064683450.031
anion transportGO:00068201780.031
monocarboxylic acid biosynthetic processGO:0072330480.030
reproductionGO:00000032450.030
Yeast
positive regulation of amine transportGO:0051954260.030
calcium ion transportGO:00068161310.030
Rat
regulation of phosphate metabolic processGO:00192203490.029
peptide hormone secretionGO:0030072840.028
locomotionGO:00400112370.028
Rat
regulation of cellular ketone metabolic processGO:0010565270.028
regulation of neuron differentiationGO:00456642080.028
regulation of hormone levelsGO:00108171870.028
regulation of peptide transportGO:0090087870.027
catabolic processGO:00090563510.027
negative regulation of rna metabolic processGO:00512531230.027
regulation of cell proliferationGO:00421273590.027
divalent inorganic cation homeostasisGO:00725071650.027
cell cell signalingGO:00072673350.027
ribonucleotide biosynthetic processGO:0009260850.027
sensory perceptionGO:00076001010.027
Mouse
cell morphogenesisGO:00009021420.026
glutamate secretionGO:0014047190.026
multicellular organism growthGO:003526410.026
regulation of metal ion transportGO:00109591180.026
Rat
calcium ion transmembrane transportGO:0070588700.026
nucleoside phosphate metabolic processGO:00067532830.026
sexual reproductionGO:00199531480.026
Yeast
negative regulation of secretionGO:0051048820.025
cellular ketone metabolic processGO:0042180510.025
positive regulation of secretionGO:00510471400.025
negative regulation of transportGO:00510511360.025
single organism catabolic processGO:00447122830.025
regulation of peptide hormone secretionGO:0090276800.025
regulation of anatomical structure sizeGO:00900661350.025
positive regulation of biosynthetic processGO:00098913190.025
hepaticobiliary system developmentGO:0061008900.025
peptidyl tyrosine modificationGO:0018212720.025
organ formationGO:004864530.025
single organism biosynthetic processGO:00447113420.025
positive regulation of fat cell differentiationGO:004560020.024
purine containing compound metabolic processGO:00725212530.024
positive regulation of cellular amine metabolic processGO:003324030.024
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.024
hormone secretionGO:00468791150.024
response to woundingGO:00096112540.024
learning or memoryGO:0007611900.023
negative regulation of transcription dna templatedGO:00458921160.023
synaptic transmissionGO:00072682350.023
pituitary gland developmentGO:0021983100.023
regulation of transferase activityGO:00513381230.023
regulation of neuron deathGO:19012141150.023
negative regulation of gene expressionGO:00106291990.023
negative regulation of peptide hormone secretionGO:0090278300.023
positive regulation of ion transportGO:0043270940.023
Rat
tissue morphogenesisGO:0048729220.023
cellular response to insulin stimulusGO:0032869810.023
positive regulation of cell communicationGO:00106472710.023
skeletal system developmentGO:0001501410.023
regulation of protein metabolic processGO:00512462890.023
carbohydrate derivative biosynthetic processGO:19011371240.022
regulation of neuron apoptotic processGO:0043523830.022
regulation of catalytic activityGO:00507903040.022
positive regulation of purine nucleotide metabolic processGO:1900544910.022
regulation of phosphorus metabolic processGO:00511743490.022
response to growth factorGO:00708481890.022
positive regulation of cellular component movementGO:00512721020.022
Rat
positive regulation of hormone secretionGO:0046887650.022
single organism intracellular transportGO:19025821660.022
negative regulation of hormone secretionGO:0046888460.022
organonitrogen compound catabolic processGO:19015651790.021
amine metabolic processGO:0009308380.021
positive regulation of nucleotide metabolic processGO:0045981910.021
gamete generationGO:00072761240.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
positive regulation of secretion by cellGO:19035321280.021
positive regulation of catalytic activityGO:00430851840.021
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.021
amide transportGO:00428861050.021
negative regulation of secretion by cellGO:1903531720.021
cellular amino acid metabolic processGO:00065201070.020
positive regulation of rna biosynthetic processGO:19026801970.020
head developmentGO:00603222470.020
Rat
cell type specific apoptotic processGO:00972851340.020
digestive tract developmentGO:0048565390.020
positive regulation of locomotionGO:00400171020.020
Rat
intracellular signal transductionGO:00355563140.020
gastrulationGO:000736920.020
sodium ion transmembrane transportGO:0035725670.019
lipid biosynthetic processGO:00086101280.019
telencephalon regionalizationGO:002197810.019
organ morphogenesisGO:0009887750.019
positive regulation of cellular protein metabolic processGO:00322701670.019
response to hexoseGO:00097461440.019
Rat
positive regulation of cellular amino acid metabolic processGO:004576410.019
ribose phosphate biosynthetic processGO:0046390870.019
motor neuron axon guidanceGO:000804510.019
response to metal ionGO:00100382530.018
Rat
liver developmentGO:0001889900.018
regulation of cellular amine metabolic processGO:003323880.018
cyclic purine nucleotide metabolic processGO:0052652620.018
single organism reproductive processGO:00447022970.018
Yeast
purine ribonucleotide biosynthetic processGO:0009152810.018
morphogenesis of embryonic epitheliumGO:001633130.018
response to epidermal growth factorGO:0070849180.018
regulation of vascular smooth muscle contractionGO:000305630.017
cellular response to acid chemicalGO:0071229750.017
Rat
response to insulinGO:00328681330.017
cellular component biogenesisGO:00440853680.017
Rat
multicellular organism reproductionGO:00325042330.017
macromolecular complex subunit organizationGO:00439333390.017
Rat
cellular response to stressGO:00335542690.017
Rat
multi multicellular organism processGO:00447061380.017
Rat
nitrogen compound transportGO:00717052290.017
Rat
blood circulationGO:00080151830.016
ribonucleoside monophosphate metabolic processGO:0009161880.016
regulation of system processGO:00440572080.016
lens fiber cell differentiationGO:007030630.016
anion transmembrane transportGO:0098656770.016
regulation of cell developmentGO:00602842630.016
maintenance of locationGO:0051235170.016
cellular response to abiotic stimulusGO:0071214850.016
Rat
positive regulation of signalingGO:00230562700.016
positive regulation of transportGO:00510502450.016
Rat
response to peptideGO:19016522920.016
Rat
negative regulation of cell proliferationGO:00082851190.016
cell morphogenesis involved in differentiationGO:00009041190.016
response to oxidative stressGO:00069791860.016
signal releaseGO:00230611450.016
positive regulation of phosphorylationGO:00423271770.016
regulation of transmembrane transportGO:00347621220.016
protein complex assemblyGO:00064612630.016
Rat
organonitrogen compound biosynthetic processGO:19015661670.016
spermatogenesisGO:0007283990.015
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.015
response to ionizing radiationGO:0010212590.015
carbohydrate metabolic processGO:00059751300.015
mesoderm developmentGO:000749820.015
positive regulation of peptide hormone secretionGO:0090277500.015
fatty acid biosynthetic processGO:0006633330.015
positive regulation of protein metabolic processGO:00512471780.015
cellular response to magnesium ionGO:007128640.015
regulation of insulin secretionGO:0050796650.015
cellular response to external stimulusGO:00714961180.015
Rat
regulation of tube sizeGO:0035150890.015
organophosphate biosynthetic processGO:00904071430.015
cellular response to nitrogen compoundGO:19016992100.015
regulation of membrane potentialGO:00423911100.014
response to carbohydrateGO:00097431830.014
Rat
digestive system developmentGO:0055123410.014
neuron projection developmentGO:00311752730.014
regulation of phosphorylationGO:00423252480.014
amino acid transportGO:0006865700.014
salivary gland developmentGO:000743130.014
response to monosaccharideGO:00342841590.014
Rat
axis specificationGO:000979840.014
female sex differentiationGO:0046660590.014
proteolysisGO:00065081750.014
positive regulation of cell proliferationGO:00082842490.014
camera type eye morphogenesisGO:004859320.014
regulation of ion transmembrane transportGO:00347651210.014
regulation of neurogenesisGO:00507672470.014
multicellular organismal reproductive processGO:00486092330.014
response to amineGO:0014075460.014
tube developmentGO:0035295890.013
organic acid transportGO:00158491160.013
g protein coupled acetylcholine receptor signaling pathwayGO:000721350.013
glycosyl compound metabolic processGO:19016571820.013
central nervous system neuron differentiationGO:0021953170.013
regulation of protein phosphorylationGO:00019321830.013
peptidyl amino acid modificationGO:00181931260.013
regulation of protein kinase activityGO:00458591050.013
ribonucleoside catabolic processGO:00424541260.013
regulation of blood vessel sizeGO:0050880890.013
positive regulation of cytosolic calcium ion concentrationGO:00072041220.013
monovalent inorganic cation transportGO:00156721720.013
cellular response to oxidative stressGO:0034599760.013
insulin secretionGO:0030073690.013
palate developmentGO:006002120.013
response to glucoseGO:00097491360.013
Rat
regulation of purine nucleotide biosynthetic processGO:1900371460.013
lipid localizationGO:0010876620.013
regulation of sodium ion transmembrane transporter activityGO:200064940.013
cellular response to carbohydrate stimulusGO:0071322720.013
Rat
developmental process involved in reproductionGO:00030061590.013
Yeast
anatomical structure formation involved in morphogenesisGO:0048646830.013
Yeast
sex differentiationGO:00075481130.013
potassium ion transportGO:0006813970.013
response to amphetamineGO:0001975250.013
calcium ion homeostasisGO:00550741620.012
negative regulation of cell communicationGO:00106481580.012
negative regulation of protein transportGO:0051224170.012
negative regulation of multicellular organismal processGO:00512412030.012
Rat
regulation of cyclic nucleotide metabolic processGO:0030799510.012
cellular response to peptideGO:19016531330.012
positive regulation of lipid kinase activityGO:009021820.012
negative regulation of signalingGO:00230571570.012
regulation of protein secretionGO:0050708280.012
camp biosynthetic processGO:0006171470.012
diencephalon developmentGO:0021536210.012
nucleobase containing compound catabolic processGO:00346551520.012
lipid storageGO:001991510.012
regulation of nucleotide biosynthetic processGO:0030808470.012
peptide biosynthetic processGO:004304330.012
cell part morphogenesisGO:00329901230.012
regulation of protein modification processGO:00313991940.012
cellular component morphogenesisGO:00329891550.012
purine containing compound biosynthetic processGO:0072522850.012
cell morphogenesis involved in neuron differentiationGO:00486671060.012
insulin like growth factor receptor signaling pathwayGO:004800930.012
immune system processGO:00023762040.011
positive regulation of cell differentiationGO:00455972170.011
protein secretionGO:0009306340.011
regulation of cell differentiationGO:00455953200.011
regulation of lipid metabolic processGO:0019216680.011
positive regulation of cytokine production involved in immune responseGO:000272020.011
cellular response to ketoneGO:1901655510.011
response to purine containing compoundGO:00140741260.011
positive regulation of peptide secretionGO:0002793520.011
neuron apoptotic processGO:0051402880.011
neuron deathGO:00709971270.011
prepulse inhibitionGO:006013410.011
embryonic epithelial tube formationGO:000183830.011
reactive nitrogen species metabolic processGO:200105710.011
s shaped body morphogenesisGO:007205020.011
spinal cord developmentGO:0021510270.011
negative regulation of response to stimulusGO:00485851550.011
calcium ion transport into cytosolGO:0060402380.011
cytoplasmic transportGO:00164821150.011
cyclic nucleotide metabolic processGO:0009187800.011
apoptotic signaling pathwayGO:0097190270.011
regulation of nucleotide metabolic processGO:00061401170.011
peptide transportGO:0015833970.011
gonad developmentGO:00084061040.011
positive regulation of hydrolase activityGO:0051345860.011
fatty acid metabolic processGO:0006631990.011
response to nicotineGO:0035094510.011
negative regulation of nervous system developmentGO:0051961790.011
intracellular protein transportGO:0006886790.011
male mating behaviorGO:006017930.011
ion homeostasisGO:00508012120.011
ventral spinal cord developmentGO:002151730.011
response to decreased oxygen levelsGO:00362932370.011
regulation of intracellular transportGO:0032386650.010
retina morphogenesis in camera type eyeGO:006004210.010
cellular response to peptide hormone stimulusGO:00713751200.010
regulation of nervous system developmentGO:00519602640.010
vasoconstrictionGO:0042310540.010
cellular response to glucocorticoid stimulusGO:0071385680.010
circulatory system processGO:00030131830.010
muscle system processGO:00030121150.010
small gtpase mediated signal transductionGO:0007264360.010
comma shaped body morphogenesisGO:007204920.010
leukocyte activationGO:0045321760.010
response to vitaminGO:00332731310.010
cell activationGO:0001775970.010
cellular response to steroid hormone stimulusGO:0071383930.010
Rat
muscle cell proliferationGO:0033002840.010
response to starvationGO:0042594590.010
Rat

Mip disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
retinitis pigmentosaDOID:1058400.084
eye and adnexa diseaseDOID:149200.084
sensory system diseaseDOID:005015500.084
retinal degenerationDOID:846600.084
retinal diseaseDOID:567900.084
nervous system diseaseDOID:86300.084
eye diseaseDOID:561400.084
disease of anatomical entityDOID:700.084
urinary system diseaseDOID:1800.068
musculoskeletal system diseaseDOID:1700.036
bone diseaseDOID:008000100.036
connective tissue diseaseDOID:6500.036
acquired metabolic diseaseDOID:006015800.012
overnutritionDOID:65400.012
nutrition diseaseDOID:37400.012
obesityDOID:997000.012
disease of metabolismDOID:001466700.012
central nervous system diseaseDOID:33100.012