IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Mpp3

membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)

(Aliases: Dlg3,CSG18,Dusp3)

Entrez: 114202
Ensembl: ENSRNOG00000033653
RGD: 620015
UniProtKB: O88954

Process Predictions
Disease Predictions

Mpp3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
carboxylic acid transport	GO:0046942	115	0.284
inorganic ion transmembrane transport	GO:0098660	229	0.261
transmembrane transport	GO:0055085	412	0.228
inorganic cation transmembrane transport	GO:0098662	202	0.187
synaptic growth at neuromuscular junction	GO:0051124	1	0.185	Fly
cation transmembrane transport	GO:0098655	263	0.172
cellular response to organic cyclic compound	GO:0071407	202	0.162
ion transmembrane transport	GO:0034220	365	0.156
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.150	Fly
cell projection organization	GO:0030030	302	0.148	Fly
organ morphogenesis	GO:0009887	75	0.144
rna metabolic process	GO:0016070	406	0.144
neuron differentiation	GO:0030182	368	0.142	Fly
vesicle mediated transport	GO:0016192	181	0.137
carbohydrate metabolic process	GO:0005975	130	0.126
neuron development	GO:0048666	286	0.119	Fly
regulation of phosphate metabolic process	GO:0019220	349	0.109
monosaccharide metabolic process	GO:0005996	61	0.106
response to extracellular stimulus	GO:0009991	380	0.105
cellular protein localization	GO:0034613	122	0.103	Rat
calcium ion transmembrane transport	GO:0070588	70	0.102
salivary gland development	GO:0007431	3	0.100
multicellular organism reproduction	GO:0032504	233	0.099
cation transport	GO:0006812	382	0.096
response to carbohydrate	GO:0009743	183	0.094
synapse organization	GO:0050808	46	0.090	Fly
response to nutrient levels	GO:0031667	370	0.086
dorsal ventral axon guidance	GO:0033563	1	0.085
organ regeneration	GO:0031100	101	0.084
macromolecule localization	GO:0033036	252	0.081	Rat
reproduction	GO:0000003	245	0.079
cellular response to hormone stimulus	GO:0032870	247	0.078
amino acid transport	GO:0006865	70	0.076
cellular response to insulin stimulus	GO:0032869	81	0.073
nucleic acid templated transcription	GO:0097659	379	0.073
rna biosynthetic process	GO:0032774	380	0.072
rhythmic process	GO:0048511	156	0.071
cell cell signaling	GO:0007267	335	0.071	Fly
response to radiation	GO:0009314	137	0.070
regulation of system process	GO:0044057	208	0.068
single organism carbohydrate metabolic process	GO:0044723	118	0.067
establishment of protein localization	GO:0045184	141	0.067	Rat
response to corticosteroid	GO:0031960	235	0.067
g protein coupled acetylcholine receptor signaling pathway	GO:0007213	5	0.063
secretion by cell	GO:0032940	248	0.062
single organism biosynthetic process	GO:0044711	342	0.062
cell morphogenesis involved in differentiation	GO:0000904	119	0.060
response to oxygen levels	GO:0070482	265	0.060
comma shaped body morphogenesis	GO:0072049	2	0.060
cerebellar purkinje cell layer development	GO:0021680	2	0.060
regulation of phosphorus metabolic process	GO:0051174	349	0.059
cellular component assembly	GO:0022607	360	0.058	Fly
positive regulation of cell communication	GO:0010647	271	0.057
cell morphogenesis involved in neuron differentiation	GO:0048667	106	0.057
single organism cellular localization	GO:1902580	102	0.056
regulation of cyclic nucleotide metabolic process	GO:0030799	51	0.055
neuron projection development	GO:0031175	273	0.054	Fly
positive regulation of transport	GO:0051050	245	0.053
regulation of molecular function	GO:0065009	398	0.053
signal release	GO:0023061	145	0.053
reproductive process	GO:0022414	372	0.051
intracellular protein transport	GO:0006886	79	0.051	Rat
transcription dna templated	GO:0006351	377	0.051
membrane organization	GO:0061024	94	0.050
protein localization	GO:0008104	191	0.049	Rat
intracellular receptor signaling pathway	GO:0030522	35	0.049
cell part morphogenesis	GO:0032990	123	0.048	Fly
intracellular signal transduction	GO:0035556	314	0.047
cellular response to endogenous stimulus	GO:0071495	377	0.047
protein autophosphorylation	GO:0046777	66	0.046
regulation of transcription dna templated	GO:0006355	374	0.046
response to monosaccharide	GO:0034284	159	0.046
monovalent inorganic cation transport	GO:0015672	172	0.045
regulation of synapse assembly	GO:0051963	15	0.045	Fly
motor neuron axon guidance	GO:0008045	1	0.045
positive regulation of multicellular organismal process	GO:0051240	387	0.044
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001241	2	0.044
neurotrophin production	GO:0032898	2	0.043
regulation of ion transport	GO:0043269	245	0.042
anatomical structure morphogenesis	GO:0009653	298	0.042	Fly
positive regulation of transferase activity	GO:0051347	81	0.042
protein oligomerization	GO:0051259	191	0.041
cellular macromolecule localization	GO:0070727	122	0.041	Rat
insulin secretion	GO:0030073	69	0.041
multicellular organismal reproductive process	GO:0048609	233	0.040
organonitrogen compound biosynthetic process	GO:1901566	167	0.040
regulation of signal transduction	GO:0009966	318	0.039
response to inorganic substance	GO:0010035	377	0.039
neuron projection morphogenesis	GO:0048812	122	0.039	Fly
lymphoid progenitor cell differentiation	GO:0002320	2	0.038
ribonucleotide metabolic process	GO:0009259	231	0.038
reproductive system development	GO:0061458	128	0.038
cerebellar purkinje cell layer morphogenesis	GO:0021692	1	0.038
exocytosis	GO:0006887	60	0.037
response to peptide hormone	GO:0043434	278	0.037
defense response	GO:0006952	194	0.037
developmental process involved in reproduction	GO:0003006	159	0.037
fructose 2 6 bisphosphate metabolic process	GO:0006003	2	0.037
regulation of rna biosynthetic process	GO:2001141	381	0.037
response to reactive oxygen species	GO:0000302	120	0.036
positive regulation of phosphatidylinositol 3 kinase activity	GO:0043552	2	0.036
endocytosis	GO:0006897	84	0.036
regeneration	GO:0031099	163	0.036
axonogenesis	GO:0007409	71	0.036
adult locomotory behavior	GO:0008344	4	0.035
negative regulation of innate immune response	GO:0045824	4	0.035
glutamate receptor signaling pathway	GO:0007215	43	0.035
single organism intracellular transport	GO:1902582	166	0.035
positive regulation of cellular protein metabolic process	GO:0032270	167	0.035
regulation of transferase activity	GO:0051338	123	0.035
response to hexose	GO:0009746	144	0.034
hexose metabolic process	GO:0019318	58	0.034
regulation of neuron differentiation	GO:0045664	208	0.034
brain development	GO:0007420	247	0.034
cellular response to stress	GO:0033554	269	0.033
forebrain development	GO:0030900	98	0.033
regulation of vesicle mediated transport	GO:0060627	81	0.033
regulation of phosphorylation	GO:0042325	248	0.033
circulatory system process	GO:0003013	183	0.033
regulation of transporter activity	GO:0032409	50	0.033
positive regulation of cellular biosynthetic process	GO:0031328	295	0.033
anion transport	GO:0006820	178	0.033
response to oxidative stress	GO:0006979	186	0.033
positive regulation of cell death	GO:0010942	184	0.032
acute inflammatory response	GO:0002526	58	0.032
metal ion transport	GO:0030001	289	0.032
positive regulation of lipid kinase activity	GO:0090218	2	0.032
heart morphogenesis	GO:0003007	3	0.032
regulation of cellular localization	GO:0060341	263	0.032
purine ribonucleotide biosynthetic process	GO:0009152	81	0.032
spinal cord development	GO:0021510	27	0.032
positive regulation of phosphate metabolic process	GO:0045937	262	0.032
tangential migration from the subventricular zone to the olfactory bulb	GO:0022028	1	0.032
cellular lipid metabolic process	GO:0044255	208	0.031
dendrite development	GO:0016358	72	0.031
organophosphate biosynthetic process	GO:0090407	143	0.031
protein heterooligomerization	GO:0051291	89	0.031
nephron tubule epithelial cell differentiation	GO:0072160	1	0.030
carbohydrate derivative biosynthetic process	GO:1901137	124	0.030
regulation of growth	GO:0040008	105	0.030	Fly
central nervous system development	GO:0007417	311	0.030
regulation of protein metabolic process	GO:0051246	289	0.030
cellular component morphogenesis	GO:0032989	155	0.030	Fly
cellular response to nitrogen compound	GO:1901699	210	0.029
response to ketone	GO:1901654	182	0.029
positive regulation of protein metabolic process	GO:0051247	178	0.029
positive regulation of phosphorylation	GO:0042327	177	0.029
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.029
adenylate cyclase inhibiting g protein coupled glutamate receptor signaling pathway	GO:0007196	5	0.029
positive regulation of protein modification process	GO:0031401	142	0.029
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.028
macromolecular complex assembly	GO:0065003	273	0.028
negative regulation of intracellular estrogen receptor signaling pathway	GO:0033147	2	0.028
regulation of cellular protein metabolic process	GO:0032268	267	0.028
embryo development	GO:0009790	49	0.028
phosphatidylinositol dephosphorylation	GO:0046856	4	0.028
negative regulation of vesicle fusion	GO:0031339	2	0.027
metanephros morphogenesis	GO:0003338	6	0.027
cellular response to peptide	GO:1901653	133	0.027
single organism reproductive process	GO:0044702	297	0.027
cell growth	GO:0016049	104	0.027
glucose metabolic process	GO:0006006	52	0.027
axon development	GO:0061564	96	0.027
regulation of nervous system development	GO:0051960	264	0.027	Fly
response to nicotine	GO:0035094	51	0.027
cellular response to oxygen containing compound	GO:1901701	386	0.027
protein transport	GO:0015031	132	0.026	Rat
neurotransmitter transport	GO:0006836	42	0.026
cellular response to organonitrogen compound	GO:0071417	197	0.026
purine nucleotide metabolic process	GO:0006163	229	0.026
neurotransmitter gated ion channel clustering	GO:0072578	3	0.026
response to ethanol	GO:0045471	162	0.026
ionotropic glutamate receptor signaling pathway	GO:0035235	34	0.026
developmental growth	GO:0048589	100	0.026	Fly
response to estrogen	GO:0043627	232	0.026
catabolic process	GO:0009056	351	0.025
positive regulation of response to stimulus	GO:0048584	285	0.025
regulation of respiratory gaseous exchange by neurological system process	GO:0002087	1	0.025
s shaped body morphogenesis	GO:0072050	2	0.025
nucleoside phosphate biosynthetic process	GO:1901293	102	0.025
regulation of multicellular organismal development	GO:2000026	376	0.025	Fly
negative regulation of cell communication	GO:0010648	158	0.025
action potential	GO:0001508	54	0.025
establishment of organelle localization	GO:0051656	37	0.025
salivary gland morphogenesis	GO:0007435	1	0.025
synapse assembly	GO:0007416	29	0.025	Fly
regulation of nucleotide metabolic process	GO:0006140	117	0.024
dephosphorylation	GO:0016311	98	0.024
metanephric part of ureteric bud development	GO:0035502	1	0.024
protein localization to organelle	GO:0033365	57	0.024
positive regulation of phosphorus metabolic process	GO:0010562	262	0.024
positive regulation of molecular function	GO:0044093	230	0.024
cell projection morphogenesis	GO:0048858	123	0.024	Fly
carboxylic acid metabolic process	GO:0019752	289	0.024
cellular catabolic process	GO:0044248	295	0.024
cellular response to growth factor stimulus	GO:0071363	162	0.024
protein tetramerization	GO:0051262	38	0.024
metanephric comma shaped body morphogenesis	GO:0072278	2	0.024
phospholipid metabolic process	GO:0006644	61	0.024
positive regulation of gene expression	GO:0010628	244	0.024
positive regulation of cellular component organization	GO:0051130	200	0.024
response to purine containing compound	GO:0014074	126	0.023
secretion	GO:0046903	307	0.023
negative regulation of phosphorus metabolic process	GO:0010563	80	0.023
protein complex subunit organization	GO:0071822	302	0.023
response to glucocorticoid	GO:0051384	223	0.023
protein localization to nucleus	GO:0034504	39	0.023
regulation of endocytosis	GO:0030100	42	0.023
potassium ion transmembrane transport	GO:0071805	71	0.023
establishment of protein localization to organelle	GO:0072594	44	0.023
reproductive structure development	GO:0048608	128	0.023
cellular component biogenesis	GO:0044085	368	0.023	Fly
carbohydrate derivative metabolic process	GO:1901135	346	0.023
innate immune response	GO:0045087	35	0.023
purine nucleotide biosynthetic process	GO:0006164	83	0.023
oxidation reduction process	GO:0055114	304	0.023
cell morphogenesis	GO:0000902	142	0.022	Fly
response to alkaloid	GO:0043279	132	0.022
regulation of hormone secretion	GO:0046883	106	0.022
anterior posterior pattern specification	GO:0009952	1	0.022
response to glucose	GO:0009749	136	0.022
regulation of rna metabolic process	GO:0051252	391	0.022
gonad development	GO:0008406	104	0.021
organic hydroxy compound metabolic process	GO:1901615	115	0.021
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.021
metanephric s shaped body morphogenesis	GO:0072284	2	0.021
metanephric glomerulus development	GO:0072224	3	0.021
head development	GO:0060322	247	0.021
regulation of axonogenesis	GO:0050770	37	0.021
ribose phosphate biosynthetic process	GO:0046390	87	0.021
dna metabolic process	GO:0006259	96	0.021
negative regulation of metabolic process	GO:0009892	331	0.020
regulation of hormone levels	GO:0010817	187	0.020
protein targeting	GO:0006605	61	0.020
axon guidance	GO:0007411	24	0.020
cyclic nucleotide metabolic process	GO:0009187	80	0.020
immune system process	GO:0002376	204	0.020
locomotory exploration behavior	GO:0035641	1	0.020
amide transport	GO:0042886	105	0.020
regulation of cell morphogenesis	GO:0022604	77	0.020
enzyme linked receptor protein signaling pathway	GO:0007167	116	0.019
positive regulation of transcription dna templated	GO:0045893	197	0.019
regulation of ion transmembrane transport	GO:0034765	121	0.019
cellular amine metabolic process	GO:0044106	38	0.019
anion transmembrane transport	GO:0098656	77	0.019
positive regulation of kinase activity	GO:0033674	77	0.019
behavior	GO:0007610	205	0.019
regulation of protein phosphorylation	GO:0001932	183	0.019
neurological system process	GO:0050877	219	0.019
protein homooligomerization	GO:0051260	91	0.019
single organism behavior	GO:0044708	130	0.019
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.019
protein phosphorylation	GO:0006468	345	0.019
ribonucleotide biosynthetic process	GO:0009260	85	0.019
positive regulation of rna metabolic process	GO:0051254	203	0.019
positive regulation of rna biosynthetic process	GO:1902680	197	0.018
regulation of cell morphogenesis involved in differentiation	GO:0010769	72	0.018
regulation of postsynaptic membrane potential	GO:0060078	25	0.018
positive regulation of catalytic activity	GO:0043085	184	0.018
negative regulation of phosphate metabolic process	GO:0045936	80	0.018
lipid modification	GO:0030258	52	0.018
circadian rhythm	GO:0007623	88	0.018
regulation of respiratory gaseous exchange	GO:0043576	2	0.018
chemical homeostasis	GO:0048878	292	0.018
hormone transport	GO:0009914	121	0.018
nitrogen compound transport	GO:0071705	229	0.018
organic acid metabolic process	GO:0006082	292	0.018
regulation of secretion by cell	GO:1903530	208	0.018
negative regulation of secretion by cell	GO:1903531	72	0.018
gland development	GO:0048732	155	0.018
regulation of proteasomal protein catabolic process	GO:0061136	4	0.018
response to calcium ion	GO:0051592	59	0.018
oxoacid metabolic process	GO:0043436	290	0.018
regulation of kinase activity	GO:0043549	117	0.017
purine ribonucleotide metabolic process	GO:0009150	227	0.017
negative regulation of cellular biosynthetic process	GO:0031327	161	0.017
regulation of catabolic process	GO:0009894	113	0.017
cytoplasmic transport	GO:0016482	115	0.017
protein complex biogenesis	GO:0070271	263	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.017
pro t cell differentiation	GO:0002572	1	0.017
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	1	0.017
negative regulation of cellular metabolic process	GO:0031324	281	0.017
metanephric renal vesicle morphogenesis	GO:0072283	3	0.017
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.017
positive regulation of signaling	GO:0023056	270	0.017
phagocytosis	GO:0006909	17	0.017
transcription from rna polymerase ii promoter	GO:0006366	252	0.017
response to hypoxia	GO:0001666	231	0.017
response to organophosphorus	GO:0046683	102	0.017
cellular response to peptide hormone stimulus	GO:0071375	120	0.017
purine containing compound biosynthetic process	GO:0072522	85	0.016
regulation of muscle system process	GO:0090257	79	0.016
regulation of cellular component organization	GO:0051128	368	0.016	Fly
positive regulation of peptide hormone secretion	GO:0090277	50	0.016
negative regulation of ion transmembrane transporter activity	GO:0032413	12	0.016
organic substance catabolic process	GO:1901575	316	0.016
response to metal ion	GO:0010038	253	0.016
positive regulation of cell projection organization	GO:0031346	111	0.016
neurotransmitter secretion	GO:0007269	33	0.016
cellular potassium ion transport	GO:0071804	72	0.016
organic acid transport	GO:0015849	116	0.016
positive regulation of secretion	GO:0051047	140	0.016
nucleotide biosynthetic process	GO:0009165	98	0.016
embryonic pattern specification	GO:0009880	1	0.016
negative regulation of signaling	GO:0023057	157	0.016
rhythmic behavior	GO:0007622	24	0.016
regulation of catalytic activity	GO:0050790	304	0.016
protein complex assembly	GO:0006461	263	0.016
regulation of neuron projection development	GO:0010975	161	0.015
programmed cell death	GO:0012501	392	0.015
neuromuscular synaptic transmission	GO:0007274	2	0.015
rhythmic synaptic transmission	GO:0060024	1	0.015
neuron death	GO:0070997	127	0.015
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering	GO:0097113	2	0.015
camp metabolic process	GO:0046058	63	0.015
cellular response to histamine	GO:0071420	3	0.015
regulation of neurotransmitter levels	GO:0001505	42	0.015
hormone metabolic process	GO:0042445	69	0.015
positive regulation of signal transduction	GO:0009967	175	0.015
negative regulation of monocyte chemotaxis	GO:0090027	2	0.015
signal transduction by phosphorylation	GO:0023014	144	0.015
regulation of neurotransmitter secretion	GO:0046928	19	0.015
multicellular organismal signaling	GO:0035637	44	0.015
signal transduction in absence of ligand	GO:0038034	5	0.015
response to hydrogen peroxide	GO:0042542	89	0.014
response to toxic substance	GO:0009636	133	0.014
gastrulation	GO:0007369	2	0.014
regulation of insulin secretion	GO:0050796	65	0.014
negative regulation of cell differentiation	GO:0045596	99	0.014
regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001239	5	0.014
response to starvation	GO:0042594	59	0.014
calcium mediated signaling using intracellular calcium source	GO:0035584	1	0.014
maintenance of location	GO:0051235	17	0.014
regulation of respiratory system process	GO:0044065	1	0.014
serotonin metabolic process	GO:0042428	3	0.014
regulation of cyclic nucleotide biosynthetic process	GO:0030802	45	0.014
negative regulation of response to stimulus	GO:0048585	155	0.014
cell differentiation in hindbrain	GO:0021533	2	0.014
prepulse inhibition	GO:0060134	1	0.014
neuromuscular process	GO:0050905	2	0.014
cellular response to extracellular stimulus	GO:0031668	73	0.014
regulation of lipid metabolic process	GO:0019216	68	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014
protein import	GO:0017038	37	0.014
endoplasmic reticulum organization	GO:0007029	1	0.014
response to insulin	GO:0032868	133	0.014
regulation of transmembrane transport	GO:0034762	122	0.014
metal ion homeostasis	GO:0055065	186	0.014
regulation of dna metabolic process	GO:0051052	60	0.014
organophosphate metabolic process	GO:0019637	370	0.014
muscle system process	GO:0003012	115	0.014
regulation of organelle organization	GO:0033043	80	0.014
regulation of cell differentiation	GO:0045595	320	0.014
response to nutrient	GO:0007584	248	0.013
regulation of nucleic acid templated transcription	GO:1903506	380	0.013
locomotor rhythm	GO:0045475	1	0.013
cellular ketone metabolic process	GO:0042180	51	0.013
regulation of humoral immune response mediated by circulating immunoglobulin	GO:0002923	1	0.013
regulation of neuron apoptotic process	GO:0043523	83	0.013
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.013
positive regulation of developmental growth	GO:0048639	29	0.013
cell cell signaling involved in cell fate commitment	GO:0045168	2	0.013
lymphocyte activation	GO:0046649	43	0.013
telencephalon development	GO:0021537	62	0.013
gliogenesis	GO:0042063	93	0.013
regulation of long term neuronal synaptic plasticity	GO:0048169	15	0.013
response to growth factor	GO:0070848	189	0.013
cellular amino acid metabolic process	GO:0006520	107	0.013
respiratory gaseous exchange	GO:0007585	4	0.013
regulation of cellular response to insulin stimulus	GO:1900076	16	0.013
insulin receptor signaling pathway	GO:0008286	24	0.013
response to camp	GO:0051591	91	0.013
positive regulation of hexokinase activity	GO:1903301	3	0.013
response to bacterium	GO:0009617	200	0.013
formation of primary germ layer	GO:0001704	1	0.012
taxis	GO:0042330	67	0.012
regulation of purine nucleotide biosynthetic process	GO:1900371	46	0.012
cellular homeostasis	GO:0019725	252	0.012
regulation of membrane potential	GO:0042391	110	0.012
glycerophospholipid metabolic process	GO:0006650	47	0.012
mitotic cell cycle process	GO:1903047	35	0.012
digestive tract mesoderm development	GO:0007502	1	0.012
regulation of cell growth	GO:0001558	85	0.012
regulation of muscle contraction	GO:0006937	53	0.012
cellular response to abiotic stimulus	GO:0071214	85	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	85	0.012
regulation of cell projection organization	GO:0031344	175	0.012
regulation of extent of cell growth	GO:0061387	25	0.012
apoptotic signaling pathway	GO:0097190	27	0.012
response to ammonium ion	GO:0060359	71	0.012
regulation of developmental growth	GO:0048638	45	0.012	Fly
endomembrane system organization	GO:0010256	48	0.012
regulation of map kinase activity	GO:0043405	53	0.012
cerebellar cortex formation	GO:0021697	2	0.012
amine metabolic process	GO:0009308	38	0.012
cerebellum morphogenesis	GO:0021587	2	0.012
jak stat cascade	GO:0007259	26	0.012
neuron projection extension	GO:1990138	26	0.012
ribose phosphate metabolic process	GO:0019693	235	0.012
regulation of mapk cascade	GO:0043408	116	0.012
negative regulation of signal transduction	GO:0009968	83	0.012
negative regulation of immune system process	GO:0002683	39	0.012
positive regulation of programmed cell death	GO:0043068	157	0.011
cellular response to nutrient levels	GO:0031669	60	0.011
membrane fusion	GO:0061025	26	0.011
regulation of neurogenesis	GO:0050767	247	0.011
neuron neuron synaptic transmission	GO:0007270	60	0.011
intracellular transport	GO:0046907	185	0.011	Rat
regulation of cellular catabolic process	GO:0031329	101	0.011
regulation of immune system process	GO:0002682	123	0.011
membrane depolarization	GO:0051899	32	0.011
regulation of synaptic vesicle endocytosis	GO:1900242	1	0.011
hair follicle development	GO:0001942	2	0.011
response to testosterone	GO:0033574	55	0.011
camera type eye morphogenesis	GO:0048593	2	0.011
eye morphogenesis	GO:0048592	4	0.011
positive regulation of cellular amine metabolic process	GO:0033240	3	0.011
negative regulation of transport	GO:0051051	136	0.011
response to cytokine	GO:0034097	215	0.011
endoplasmic reticulum membrane organization	GO:0090158	1	0.011
positive regulation of synaptic vesicle exocytosis	GO:2000302	3	0.011
establishment of synaptic vesicle localization	GO:0097480	23	0.011
single organism membrane organization	GO:0044802	74	0.011
negative regulation of nucleotide metabolic process	GO:0045980	23	0.011
regulation of cell development	GO:0060284	263	0.011
dendrite morphogenesis	GO:0048813	43	0.011
regulation of ion transmembrane transporter activity	GO:0032412	48	0.011
negative regulation of cardiac muscle tissue growth	GO:0055022	3	0.011
locomotion	GO:0040011	237	0.011
detection of calcium ion	GO:0005513	1	0.011
developmental growth involved in morphogenesis	GO:0060560	33	0.011
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	2	0.011
l glutamate import	GO:0051938	2	0.011
leukocyte mediated immunity	GO:0002443	28	0.011
growth	GO:0040007	165	0.011	Fly
acylglycerol homeostasis	GO:0055090	2	0.011
macromolecule catabolic process	GO:0009057	58	0.011
detection of visible light	GO:0009584	3	0.011
regulation of protein homodimerization activity	GO:0043496	5	0.011
positive regulation of developmental process	GO:0051094	283	0.011
dna replication	GO:0006260	37	0.011
cell cycle	GO:0007049	101	0.011
regulation of cellular amino acid metabolic process	GO:0006521	2	0.010
purine nucleotide catabolic process	GO:0006195	136	0.010
relaxation of muscle	GO:0090075	4	0.010
regulation of nucleotide biosynthetic process	GO:0030808	47	0.010
gamma aminobutyric acid transport	GO:0015812	8	0.010
mesoderm development	GO:0007498	2	0.010
monocarboxylic acid transport	GO:0015718	52	0.010
lipid metabolic process	GO:0006629	283	0.010
vesicle organization	GO:0016050	29	0.010
regulation of defense response	GO:0031347	68	0.010
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.010
positive regulation of protein phosphorylation	GO:0001934	135	0.010
lipid storage	GO:0019915	1	0.010
response to mechanical stimulus	GO:0009612	134	0.010
hematopoietic progenitor cell differentiation	GO:0002244	2	0.010
negative regulation of cell death	GO:0060548	229	0.010

Mpp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
disease of mental health	DOID:150	0.020
substance dependence	DOID:9973	0.020
substance related disorder	DOID:303	0.020
disease of anatomical entity	DOID:7	0.019
nervous system disease	DOID:863	0.019
central nervous system disease	DOID:331	0.016
epilepsy syndrome	DOID:1826	0.016
brain disease	DOID:936	0.016
inherited metabolic disorder	DOID:655	0.012
disease of metabolism	DOID:0014667	0.012
electroclinical syndrome	DOID:0050701	0.011

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