Rattus norvegicus

15 known processes

Nlrp6

NLR family, pyrin domain containing 6

(Aliases: Nalp6)

Nlrp6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to inorganic substanceGO:00100353770.624
transmembrane transportGO:00550854120.463
ion transmembrane transportGO:00342203650.435
response to nutrientGO:00075842480.402
regulation of ion transportGO:00432692450.381
cellular response to oxygen containing compoundGO:19017013860.332
response to external biotic stimulusGO:00432072210.320
macromolecule localizationGO:00330362520.276
response to extracellular stimulusGO:00099913800.269
response to nutrient levelsGO:00316673700.267
carboxylic acid metabolic processGO:00197522890.266
response to glucocorticoidGO:00513842230.261
response to biotic stimulusGO:00096072260.222
response to peptideGO:19016522920.221
estrogen biosynthetic processGO:000670360.201
regulation of secretionGO:00510462240.200
cellular amino acid metabolic processGO:00065201070.194
cellular response to hormone stimulusGO:00328702470.190
monocarboxylic acid transportGO:0015718520.183
cellular response to organonitrogen compoundGO:00714171970.181
regulation of nucleic acid templated transcriptionGO:19035063800.180
cellular response to endogenous stimulusGO:00714953770.179
cellular response to peptide hormone stimulusGO:00713751200.178
transcription dna templatedGO:00063513770.174
response to toxic substanceGO:00096361330.172
apoptotic processGO:00069153810.166
androgen biosynthetic processGO:0006702100.162
response to corticosteroidGO:00319602350.161
positive regulation of multicellular organismal processGO:00512403870.160
protein complex biogenesisGO:00702712630.157
regulation of secretion by cellGO:19035302080.157
regulation of multicellular organismal developmentGO:20000263760.155
chemical homeostasisGO:00488782920.153
response to other organismGO:00517072200.152
response to peptide hormoneGO:00434342780.152
tissue developmentGO:00098882520.151
positive regulation of cell communicationGO:00106472710.146
regulation of cellular localizationGO:00603412630.145
cation transportGO:00068123820.138
response to vitaminGO:00332731310.135
homeostatic processGO:00425923310.130
response to bacteriumGO:00096172000.128
organonitrogen compound biosynthetic processGO:19015661670.127
cellular ion homeostasisGO:00068731840.125
positive regulation of signalingGO:00230562700.123
metal ion transportGO:00300012890.121
response to molecule of bacterial originGO:00022371940.118
oxoacid metabolic processGO:00434362900.118
neurological system processGO:00508772190.118
defense responseGO:00069521940.113
response to oxygen levelsGO:00704822650.112
regulation of transcription dna templatedGO:00063553740.111
response to metal ionGO:00100382530.111
regulation of metal ion transportGO:00109591180.106
secretionGO:00469033070.106
positive regulation of secretionGO:00510471400.104
protein localizationGO:00081041910.102
anatomical structure morphogenesisGO:00096532980.099
cellular hormone metabolic processGO:0034754490.098
cellular component assemblyGO:00226073600.097
cellular response to organic cyclic compoundGO:00714072020.095
carbohydrate derivative metabolic processGO:19011353460.094
response to oxidative stressGO:00069791860.093
positive regulation of cell deathGO:00109421840.093
rna biosynthetic processGO:00327743800.092
cellular response to peptideGO:19016531330.091
single organism catabolic processGO:00447122830.091
cellular ketone metabolic processGO:0042180510.091
ion homeostasisGO:00508012120.090
inflammatory responseGO:00069541500.089
cellular cation homeostasisGO:00300031800.087
positive regulation of apoptotic processGO:00430651540.084
cellular response to lipidGO:00713962010.082
alpha amino acid metabolic processGO:1901605710.082
cellular response to nitrogen compoundGO:19016992100.082
positive regulation of response to stimulusGO:00485842850.081
multicellular organismal reproductive processGO:00486092330.081
regulation of blood pressureGO:0008217830.081
brain developmentGO:00074202470.081
nitrogen compound transportGO:00717052290.080
response to mineralocorticoidGO:0051385490.080
positive regulation of cytosolic calcium ion concentrationGO:00072041220.079
positive regulation of cellular biosynthetic processGO:00313282950.079
macromolecular complex subunit organizationGO:00439333390.078
carboxylic acid transportGO:00469421150.078
cation homeostasisGO:00550801950.077
organic acid metabolic processGO:00060822920.076
reproductive processGO:00224143720.076
cellular chemical homeostasisGO:00550822470.075
lipid localizationGO:0010876620.075
anion transportGO:00068201780.075
cellular catabolic processGO:00442482950.074
cell cell signalingGO:00072673350.073
organelle organizationGO:00069962660.073
cellular component biogenesisGO:00440853680.072
cellular response to alcoholGO:0097306870.072
positive regulation of developmental processGO:00510942830.071
intestinal absorptionGO:005089230.070
response to cocaineGO:0042220390.069
positive regulation of macromolecule biosynthetic processGO:00105572470.069
programmed cell deathGO:00125013920.068
regulation of heart contractionGO:0008016480.068
response to decreased oxygen levelsGO:00362932370.068
cell activationGO:0001775970.068
organ morphogenesisGO:0009887750.068
regulation of membrane potentialGO:00423911100.066
regulation of molecular functionGO:00650093980.066
cellular response to stressGO:00335542690.065
response to reactive oxygen speciesGO:00003021200.065
organophosphate biosynthetic processGO:00904071430.064
regulation of intracellular signal transductionGO:19025312180.063
regulation of rna biosynthetic processGO:20011413810.061
central nervous system developmentGO:00074173110.061
cellular calcium ion homeostasisGO:00068741600.060
negative regulation of ion transportGO:0043271510.059
regulation of cell differentiationGO:00455953200.059
single organism behaviorGO:00447081300.059
organic anion transportGO:00157111320.058
positive regulation of phosphorylationGO:00423271770.058
regulation of cellular ketone metabolic processGO:0010565270.058
cellular amine metabolic processGO:0044106380.058
single organism biosynthetic processGO:00447113420.058
positive regulation of programmed cell deathGO:00430681570.057
lipid transportGO:0006869610.057
cellular homeostasisGO:00197252520.057
amide biosynthetic processGO:0043604100.056
organic hydroxy compound transportGO:0015850770.056
purine nucleoside monophosphate metabolic processGO:0009126840.056
nucleic acid templated transcriptionGO:00976593790.054
purine ribonucleoside monophosphate catabolic processGO:0009169550.054
multicellular organism reproductionGO:00325042330.053
positive regulation of secretion by cellGO:19035321280.053
multicellular organismal homeostasisGO:0048871490.053
regulation of cellular amine metabolic processGO:003323880.052
regulation of phosphorylationGO:00423252480.052
small molecule biosynthetic processGO:00442831240.051
response to vitamin dGO:0033280340.051
intracellular transportGO:00469071850.051
response to transition metal nanoparticleGO:19902671220.050
response to purine containing compoundGO:00140741260.050
cellular amino acid biosynthetic processGO:0008652320.050
acid secretionGO:0046717480.050
positive regulation of nucleic acid templated transcriptionGO:19035081970.050
regulation of signal transductionGO:00099663180.049
positive regulation of rna metabolic processGO:00512542030.049
regulation of muscle contractionGO:0006937530.049
positive regulation of cell proliferationGO:00082842490.049
cellular response to corticosteroid stimulusGO:0071384690.049
regulation of apoptotic processGO:00429813350.048
neuronal action potentialGO:0019228350.048
cellular response to insulin stimulusGO:0032869810.048
calcium ion homeostasisGO:00550741620.048
response to hydrogen peroxideGO:0042542890.048
negative regulation of programmed cell deathGO:00430691830.047
agingGO:00075682410.047
cellular response to glucocorticoid stimulusGO:0071385680.047
head developmentGO:00603222470.047
progesterone biosynthetic processGO:000670130.046
rna metabolic processGO:00160704060.046
regulation of cellular amino acid metabolic processGO:000652120.046
regenerationGO:00310991630.045
nucleoside monophosphate metabolic processGO:0009123930.045
negative regulation of metabolic processGO:00098923310.045
regulation of hormone levelsGO:00108171870.045
single organism intracellular transportGO:19025821660.045
regulation of calcium ion transportGO:0051924770.044
response to woundingGO:00096112540.044
nucleotide metabolic processGO:00091172790.044
negative regulation of apoptotic processGO:00430661810.044
negative regulation of molecular functionGO:00440921330.043
response to hypoxiaGO:00016662310.043
positive regulation of gene expressionGO:00106282440.043
digestionGO:0007586260.043
reproductive structure developmentGO:00486081280.043
circulatory system processGO:00030131830.043
protein oligomerizationGO:00512591910.043
lipid metabolic processGO:00066292830.042
response to growth factorGO:00708481890.042
cellular response to steroid hormone stimulusGO:0071383930.041
immune system processGO:00023762040.041
anion transmembrane transportGO:0098656770.041
divalent inorganic cation transportGO:00725111340.041
response to acid chemicalGO:00011012220.041
striated muscle contractionGO:0006941440.041
regulation of system processGO:00440572080.041
divalent metal ion transportGO:00708381320.041
epithelium developmentGO:0060429960.041
cellular divalent inorganic cation homeostasisGO:00725031620.041
organic acid biosynthetic processGO:0016053830.040
response to lipopolysaccharideGO:00324961910.040
amine metabolic processGO:0009308380.039
secretion by cellGO:00329402480.039
protein complex assemblyGO:00064612630.039
positive regulation of transcription dna templatedGO:00458931970.039
hormone mediated signaling pathwayGO:0009755230.039
heart processGO:0003015570.038
atp metabolic processGO:0046034720.038
regulation of programmed cell deathGO:00430673410.038
positive regulation of rna biosynthetic processGO:19026801970.038
intracellular signal transductionGO:00355563140.038
response to insecticideGO:0017085210.037
muscle system processGO:00030121150.037
single organism reproductive processGO:00447022970.037
leukocyte activationGO:0045321760.036
sodium ion transportGO:0006814820.036
catabolic processGO:00090563510.036
response to alkaloidGO:00432791320.036
negative regulation of cellular biosynthetic processGO:00313271610.035
testosterone biosynthetic processGO:006137050.035
regulation of cell developmentGO:00602842630.035
regulation of homeostatic processGO:00328441010.035
response to cytokineGO:00340972150.035
organic substance catabolic processGO:19015753160.034
negative regulation of transportGO:00510511360.034
positive regulation of cellular amine metabolic processGO:003324030.034
androgen metabolic processGO:0008209140.034
regulation of nervous system developmentGO:00519602640.034
positive regulation of cell differentiationGO:00455972170.034
sulfur compound metabolic processGO:0006790700.034
g protein coupled receptor signaling pathwayGO:00071862420.034
cytosolic calcium ion homeostasisGO:00514801400.033
positive regulation of hormone secretionGO:0046887650.033
positive regulation of erk1 and erk2 cascadeGO:0070374290.033
actin filament based processGO:0030029860.033
cation transmembrane transportGO:00986552630.033
amide transportGO:00428861050.033
positive regulation of immune system processGO:0002684900.033
regulation of response to external stimulusGO:00321011060.032
heart contractionGO:0060047570.032
response to insulinGO:00328681330.032
cellular protein localizationGO:00346131220.032
positive regulation of cellular protein metabolic processGO:00322701670.032
response to estradiolGO:00323551640.032
positive regulation of ion transportGO:0043270940.031
atp catabolic processGO:0006200540.031
purine ribonucleoside monophosphate metabolic processGO:0009167840.031
positive regulation of biosynthetic processGO:00098913190.031
epithelial cell differentiationGO:0030855710.031
response to fungicideGO:0060992200.031
response to estrogenGO:00436272320.031
small gtpase mediated signal transductionGO:0007264360.031
regulation of catecholamine secretionGO:0050433320.031
cellular metal ion homeostasisGO:00068751720.030
limb morphogenesisGO:003510840.030
peptide biosynthetic processGO:004304330.030
regulation of anion transportGO:0044070430.029
regulation of establishment of protein localizationGO:0070201690.029
negative regulation of cell deathGO:00605482290.029
response to carbohydrateGO:00097431830.029
heart morphogenesisGO:000300730.029
action potentialGO:0001508540.029
growthGO:00400071650.028
immune responseGO:00069551040.028
male gonad developmentGO:0008584590.028
reproductionGO:00000032450.028
response to dexamethasoneGO:0071548490.028
regulation of homotypic cell cell adhesionGO:003411040.028
behaviorGO:00076102050.028
regulation of body fluid levelsGO:0050878900.028
sexual reproductionGO:00199531480.028
vesicle mediated transportGO:00161921810.027
telencephalon developmentGO:0021537620.027
response to molecule of fungal originGO:000223830.027
regulation of phosphate metabolic processGO:00192203490.027
blood circulationGO:00080151830.027
multi multicellular organism processGO:00447061380.027
regulation of sodium ion transmembrane transporter activityGO:200064940.027
response to antibioticGO:0046677390.027
protein complex subunit organizationGO:00718223020.026
regulation of neuron differentiationGO:00456642080.026
positive regulation of transportGO:00510502450.026
regulation of phosphorus metabolic processGO:00511743490.025
developmental process involved in reproductionGO:00030061590.025
signal releaseGO:00230611450.025
negative regulation of transcription regulatory region dna bindingGO:200067820.025
regulation of muscle system processGO:0090257790.025
cellular response to oxidative stressGO:0034599760.025
regulation of neurogenesisGO:00507672470.025
response to amino acidGO:0043200750.025
regulation of organelle organizationGO:0033043800.025
regulation of transcription from rna polymerase ii promoterGO:00063572340.025
neuron differentiationGO:00301823680.025
nucleobase containing small molecule metabolic processGO:00550863160.025
heart developmentGO:0007507720.024
neuropeptide signaling pathwayGO:0007218290.024
digestive system processGO:0022600240.024
reproductive system developmentGO:00614581280.024
regulation of cell proliferationGO:00421273590.024
regulation of rna metabolic processGO:00512523910.024
regulation of organic acid transportGO:0032890350.024
divalent inorganic cation homeostasisGO:00725071650.024
response to lead ionGO:0010288330.024
steroid metabolic processGO:0008202730.024
hormone secretionGO:00468791150.024
organophosphate metabolic processGO:00196373700.024
positive regulation of cellular component organizationGO:00511302000.024
gamete generationGO:00072761240.023
inorganic ion transmembrane transportGO:00986602290.023
cellular response to extracellular stimulusGO:0031668730.023
cytoskeleton organizationGO:00070101110.023
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.023
positive regulation of catalytic activityGO:00430851840.023
gland developmentGO:00487321550.023
aromatic compound catabolic processGO:00194391680.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
regulation of protein localizationGO:0032880810.023
spermatogenesisGO:0007283990.023
estrogen metabolic processGO:0008210110.023
neuron developmentGO:00486662860.023
small molecule catabolic processGO:0044282590.023
organic cyclic compound catabolic processGO:19013611750.022
regulation of anatomical structure sizeGO:00900661350.022
response to ethanolGO:00454711620.022
response to hexoseGO:00097461440.022
macromolecular complex assemblyGO:00650032730.022
transcription from rna polymerase ii promoterGO:00063662520.022
catecholamine secretionGO:0050432330.022
catecholamine transportGO:0051937370.022
purine nucleoside metabolic processGO:00422781690.022
alcohol metabolic processGO:0006066770.022
limbic system developmentGO:0021761380.022
regulation of ion transmembrane transportGO:00347651210.022
positive regulation of nitrogen compound metabolic processGO:00511733340.022
regulation of response to stressGO:00801341260.022
nucleotide catabolic processGO:00091661390.021
response to starvationGO:0042594590.021
fatty acid transportGO:0015908250.021
negative regulation of multicellular organismal processGO:00512412030.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
single organism organelle organizationGO:19025891800.021
organonitrogen compound catabolic processGO:19015651790.021
negative regulation of signalingGO:00230571570.021
organophosphate catabolic processGO:00464341480.021
response to herbicideGO:0009635160.021
cellular macromolecule localizationGO:00707271220.021
response to coldGO:0009409290.021
response to ammonium ionGO:0060359710.021
odontogenesisGO:0042476320.021
memoryGO:0007613540.021
negative regulation of cellular metabolic processGO:00313242810.021
heterocycle catabolic processGO:00467001670.021
regulation of transmembrane transportGO:00347621220.021
positive regulation of neurogenesisGO:00507691650.021
carbohydrate derivative catabolic processGO:19011361470.021
response to vitamin eGO:0033197240.020
fatty acid oxidationGO:0019395290.020
ribonucleotide biosynthetic processGO:0009260850.020
pancreatic stellate cell proliferationGO:007234320.020
cellular response to reactive oxygen speciesGO:0034614550.020
cellular response to xenobiotic stimulusGO:0071466190.020
regulation of neuron deathGO:19012141150.020
nucleoside phosphate biosynthetic processGO:19012931020.020
positive regulation of phosphate metabolic processGO:00459372620.020
ossificationGO:0001503700.020
positive regulation of signal transductionGO:00099671750.020
hormone transportGO:00099141210.020
regulation of catalytic activityGO:00507903040.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
metal ion homeostasisGO:00550651860.020
negative regulation of biosynthetic processGO:00098901680.019
multi organism reproductive processGO:00447032620.019
response to heatGO:0009408600.019
rhythmic processGO:00485111560.019
regulation of amine transportGO:0051952540.019
positive regulation of synaptic transmissionGO:0050806620.019
response to monosaccharideGO:00342841590.019
cognitionGO:0050890920.019
cellular lipid metabolic processGO:00442552080.019
peptidyl amino acid modificationGO:00181931260.019
glycosyl compound metabolic processGO:19016571820.019
maintenance of locationGO:0051235170.019
regulation of reactive oxygen species metabolic processGO:2000377260.019
learning or memoryGO:0007611900.019
negative regulation of transcription dna templatedGO:00458921160.019
cellular response to vitamin dGO:0071305120.019
regulation of pancreatic stellate cell proliferationGO:200022920.019
negative regulation of macromolecule metabolic processGO:00106052600.018
acute inflammatory responseGO:0002526580.018
respiratory system developmentGO:0060541450.018
cytoplasmic transportGO:00164821150.018
positive regulation of molecular functionGO:00440932300.018
molting cycle processGO:002240420.018
ras protein signal transductionGO:0007265290.018
negative regulation of blood pressureGO:0045776290.017
response to corticosteroneGO:0051412400.017
regulation of protein metabolic processGO:00512462890.017
purine nucleotide metabolic processGO:00061632290.017
olfactory behaviorGO:004204820.017
response to activityGO:0014823730.017
regulation of reactive oxygen species biosynthetic processGO:190342650.017
nucleoside phosphate metabolic processGO:00067532830.017
diterpenoid metabolic processGO:0016101330.017
sex differentiationGO:00075481130.017
neuron deathGO:00709971270.017
carboxylic acid biosynthetic processGO:0046394830.017
urinary tract smooth muscle contractionGO:001484840.017
multicellular organismal response to stressGO:0033555250.017
regulation of neuron apoptotic processGO:0043523830.017
cellular response to hypoxiaGO:0071456510.017
single organism cellular localizationGO:19025801020.017
positive regulation of cell developmentGO:00107201760.017
tissue remodelingGO:0048771400.017
leukocyte activation involved in immune responseGO:0002366160.017
negative regulation of catalytic activityGO:00430861030.017
molting cycleGO:004230330.017
purine nucleotide biosynthetic processGO:0006164830.016
synaptic transmissionGO:00072682350.016
peptide transportGO:0015833970.016
ribonucleotide metabolic processGO:00092592310.016
nucleoside metabolic processGO:00091161790.016
cellular response to ketoneGO:1901655510.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
receptor mediated endocytosisGO:0006898420.016
positive regulation of blood circulationGO:1903524650.016
cofactor metabolic processGO:0051186950.016
tetrahydrofolate metabolic processGO:004665390.016
establishment of protein localizationGO:00451841410.016
developmental growthGO:00485891000.016
male gamete generationGO:0048232990.016
regulation of erk1 and erk2 cascadeGO:0070372410.016
organic acid transportGO:00158491160.016
organic hydroxy compound metabolic processGO:19016151150.016
cellular nitrogen compound catabolic processGO:00442701630.016
negative regulation of cell communicationGO:00106481580.016
c21 steroid hormone biosynthetic processGO:0006700100.016
negative regulation of rna metabolic processGO:00512531230.016
positive regulation of cellular component movementGO:00512721020.016
muscle contractionGO:0006936880.016
response to fatty acidGO:0070542650.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
positive regulation of nervous system developmentGO:00519621780.015
positive regulation of intracellular signal transductionGO:19025331380.015
negative regulation of nitrogen compound metabolic processGO:00511721610.015
glucose homeostasisGO:0042593750.015
regulation of neuron projection developmentGO:00109751610.015
forebrain developmentGO:0030900980.015
circadian rhythmGO:0007623880.015
positive regulation of leukocyte proliferationGO:0070665200.015
glial cell differentiationGO:0010001650.015
cellular response to cytokine stimulusGO:00713451270.015
purine containing compound metabolic processGO:00725212530.015
response to organophosphorusGO:00466831020.015
regulation of transcription regulatory region dna bindingGO:200067740.015
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.015
calcium ion importGO:0070509220.015
response to ketoneGO:19016541820.015
response to zinc ionGO:0010043390.015
development of primary male sexual characteristicsGO:0046546590.015
negative regulation of gene expressionGO:00106291990.015
positive regulation of insulin secretionGO:0032024360.015
response to gonadotropinGO:0034698340.015
endocrine system developmentGO:0035270300.015
regulation of blood vessel sizeGO:0050880890.014
inorganic cation transmembrane transportGO:00986622020.014
carbohydrate derivative biosynthetic processGO:19011371240.014
axis specificationGO:000979840.014
apoptotic signaling pathwayGO:0097190270.014
purine ribonucleotide metabolic processGO:00091502270.014
vasodilationGO:0042311440.014
coenzyme metabolic processGO:0006732860.014
carbohydrate metabolic processGO:00059751300.014
striated muscle tissue developmentGO:0014706580.014
developmental inductionGO:003112820.014
ribose phosphate biosynthetic processGO:0046390870.014
leukocyte differentiationGO:0002521300.014
purine ribonucleotide catabolic processGO:00091541360.014
organ regenerationGO:00311001010.014
positive regulation of peptide secretionGO:0002793520.014
cellular response to external stimulusGO:00714961180.014
carbohydrate homeostasisGO:0033500750.014
toxin transportGO:190199830.014
antibiotic transportGO:004289120.014
regulation of synaptic transmissionGO:00508041410.014
reactive oxygen species metabolic processGO:0072593370.014
negative regulation of developmental processGO:00510931250.014
development of primary sexual characteristicsGO:00451371070.014
cellular response to gonadotropin stimulusGO:0071371170.014
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.014
insecticide metabolic processGO:001714340.013
purine nucleoside monophosphate catabolic processGO:0009128550.013
regulation of cell projection organizationGO:00313441750.013
regulation of cytoskeleton organizationGO:0051493490.013
fractalkine metabolic processGO:005075630.013
positive regulation of lipid kinase activityGO:009021820.013
cellular response to inorganic substanceGO:0071241650.013
response to tumor necrosis factorGO:0034612560.013
maternal process involved in female pregnancyGO:0060135380.013
insulin secretionGO:0030073690.013

Nlrp6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.107
disease of anatomical entityDOID:700.107
disease of metabolismDOID:001466700.036
inherited metabolic disorderDOID:65500.032
connective tissue diseaseDOID:6500.023
nervous system diseaseDOID:86300.023
sensory system diseaseDOID:005015500.018
bone diseaseDOID:008000100.017
central nervous system diseaseDOID:33100.015