Rattus norvegicus

14 known processes

Pacs1

phosphofurin acidic cluster sorting protein 1

(Aliases: Pacs-1)

Pacs1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of rna metabolic processGO:00512523910.464
transcription from rna polymerase ii promoterGO:00063662520.393
cell projection morphogenesisGO:00488581230.337
cell morphogenesis involved in differentiationGO:00009041190.326
neuron projection morphogenesisGO:00488121220.317
regulation of transcription dna templatedGO:00063553740.302
learning or memoryGO:0007611900.261
anatomical structure morphogenesisGO:00096532980.259
macromolecular complex subunit organizationGO:00439333390.244
cell cell signalingGO:00072673350.232
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.229
synaptic transmissionGO:00072682350.225
nucleic acid templated transcriptionGO:00976593790.206
regulation of transcription from rna polymerase ii promoterGO:00063572340.203
rna biosynthetic processGO:00327743800.185
rna metabolic processGO:00160704060.176
dendrite morphogenesisGO:0048813430.176
intracellular signal transductionGO:00355563140.168
cell part morphogenesisGO:00329901230.152
positive regulation of nucleobase containing compound metabolic processGO:00459353190.150
transcription dna templatedGO:00063513770.148
cell projection organizationGO:00300303020.143
positive regulation of transcription dna templatedGO:00458931970.133
vesicle mediated transportGO:00161921810.129
Mouse
positive regulation of cell differentiationGO:00455972170.127
protein complex biogenesisGO:00702712630.124
negative regulation of signal transductionGO:0009968830.123
cell morphogenesis involved in neuron differentiationGO:00486671060.121
regulation of phosphate metabolic processGO:00192203490.119
regulation of neuron differentiationGO:00456642080.118
regulation of synaptic transmissionGO:00508041410.117
cellular component biogenesisGO:00440853680.117
macromolecular complex assemblyGO:00650032730.116
regulation of jun kinase activityGO:0043506100.116
urogenital system developmentGO:0001655780.114
apoptotic processGO:00069153810.114
dendrite developmentGO:0016358720.111
regulation of cell morphogenesis involved in differentiationGO:0010769720.110
regulation of signal transductionGO:00099663180.110
protein localizationGO:00081041910.106
chemotaxisGO:0006935660.104
positive regulation of rna biosynthetic processGO:19026801970.103
cell motilityGO:00488702020.103
protein complex subunit organizationGO:00718223020.103
renal system developmentGO:0072001670.100
negative regulation of metabolic processGO:00098923310.098
regulation of phosphorus metabolic processGO:00511743490.095
macromolecule localizationGO:00330362520.094
regulation of synaptic plasticityGO:0048167700.094
regulation of nervous system developmentGO:00519602640.093
cellular protein localizationGO:00346131220.092
positive regulation of nitrogen compound metabolic processGO:00511733340.091
neuromuscular synaptic transmissionGO:000727420.091
positive regulation of rna metabolic processGO:00512542030.089
regulation of rna biosynthetic processGO:20011413810.087
regulation of cell developmentGO:00602842630.086
heart morphogenesisGO:000300730.085
neuron differentiationGO:00301823680.084
protein complex assemblyGO:00064612630.083
taxisGO:0042330670.082
localization of cellGO:00516742020.082
dna metabolic processGO:0006259960.081
negative regulation of cellular metabolic processGO:00313242810.080
multi organism reproductive processGO:00447032620.079
cellular component assemblyGO:00226073600.078
exocytosisGO:0006887600.077
negative regulation of cell communicationGO:00106481580.076
cardiac chamber developmentGO:000320510.076
neuron projection developmentGO:00311752730.075
signal transduction in absence of ligandGO:003803450.074
locomotionGO:00400112370.073
positive regulation of signalingGO:00230562700.073
programmed cell deathGO:00125013920.073
cell morphogenesisGO:00009021420.073
behavioral response to nicotineGO:003509520.071
regulation of molecular functionGO:00650093980.069
positive regulation of macromolecule biosynthetic processGO:00105572470.069
cell migrationGO:00164771970.067
regulation of cellular component organizationGO:00511283680.067
cellular component movementGO:00069282480.066
reproductive processGO:00224143720.066
multicellular organism reproductionGO:00325042330.065
neuron developmentGO:00486662860.064
response to monosaccharideGO:00342841590.064
axon guidanceGO:0007411240.063
neurotransmitter transportGO:0006836420.062
positive regulation of cellular biosynthetic processGO:00313282950.062
cell type specific apoptotic processGO:00972851340.061
positive regulation of signal transductionGO:00099671750.061
regulation of secretionGO:00510462240.060
multicellular organismal reproductive processGO:00486092330.060
regulation of multicellular organismal developmentGO:20000263760.060
regulation of apoptotic processGO:00429813350.060
positive regulation of biosynthetic processGO:00098913190.060
regulation of cellular component biogenesisGO:0044087860.059
negative regulation of cellular biosynthetic processGO:00313271610.059
kidney developmentGO:0001822670.058
single organism behaviorGO:00447081300.058
regulation of nucleic acid templated transcriptionGO:19035063800.058
negative regulation of biosynthetic processGO:00098901680.058
positive regulation of multicellular organismal processGO:00512403870.058
positive regulation of neurogenesisGO:00507691650.057
positive regulation of cell communicationGO:00106472710.057
regulation of intracellular signal transductionGO:19025312180.057
sexual reproductionGO:00199531480.056
bmp signaling pathwayGO:003050940.056
negative regulation of cell deathGO:00605482290.056
positive regulation of cell developmentGO:00107201760.055
response to metal ionGO:00100382530.053
developmental process involved in reproductionGO:00030061590.053
negative regulation of apoptotic processGO:00430661810.052
positive regulation of gene expressionGO:00106282440.052
protein transportGO:00150311320.052
Human Mouse
reproductionGO:00000032450.051
epithelium developmentGO:0060429960.051
behaviorGO:00076102050.051
extrinsic apoptotic signaling pathway in absence of ligandGO:009719250.049
head developmentGO:00603222470.049
positive regulation of nucleic acid templated transcriptionGO:19035081970.049
membrane organizationGO:0061024940.048
Human
negative regulation of nitrogen compound metabolic processGO:00511721610.048
regulation of neurogenesisGO:00507672470.048
positive regulation of cell deathGO:00109421840.047
positive regulation of response to stimulusGO:00485842850.047
regulation of programmed cell deathGO:00430673410.047
cellular macromolecule localizationGO:00707271220.046
cardiac ventricle developmentGO:000323110.046
axon developmentGO:0061564960.045
positive regulation of phosphate metabolic processGO:00459372620.045
negative regulation of macromolecule biosynthetic processGO:00105581480.045
epoxygenase p450 pathwayGO:001937310.045
regulation of anatomical structure morphogenesisGO:00226031410.044
circulatory system processGO:00030131830.044
mesoderm developmentGO:000749820.044
motor neuron axon guidanceGO:000804510.043
male mating behaviorGO:006017930.042
secretionGO:00469033070.042
negative regulation of programmed cell deathGO:00430691830.041
regulation of cell cycleGO:0051726730.041
secretion by cellGO:00329402480.040
cognitionGO:0050890920.040
positive regulation of nervous system developmentGO:00519621780.040
anterior posterior pattern specificationGO:000995210.039
cellular ketone metabolic processGO:0042180510.039
mitotic cell cycle phase transitionGO:0044772200.039
male gonad developmentGO:0008584590.039
negative regulation of signalingGO:00230571570.039
negative regulation of multicellular organismal processGO:00512412030.038
regulation of system processGO:00440572080.038
central nervous system developmentGO:00074173110.037
regulation of cell differentiationGO:00455953200.037
regulation of neurotransmitter levelsGO:0001505420.037
single organism reproductive processGO:00447022970.036
response to acid chemicalGO:00011012220.036
cellular response to oxygen containing compoundGO:19017013860.036
embryonic pattern specificationGO:000988010.035
negative regulation of rna metabolic processGO:00512531230.035
positive regulation of developmental processGO:00510942830.035
ameboidal type cell migrationGO:0001667260.035
response to peptide hormoneGO:00434342780.034
regulation of cell proliferationGO:00421273590.034
response to calcium ionGO:0051592590.034
tube developmentGO:0035295890.034
positive regulation of cellular component organizationGO:00511302000.033
protein phosphorylationGO:00064683450.033
negative regulation of transcription dna templatedGO:00458921160.033
response to ethanolGO:00454711620.032
negative regulation of intracellular signal transductionGO:1902532380.032
regulation of protein phosphorylationGO:00019321830.031
single organism catabolic processGO:00447122830.031
brain developmentGO:00074202470.030
sex differentiationGO:00075481130.030
cell cycleGO:00070491010.030
regulation of dendrite morphogenesisGO:0048814330.030
limbic system developmentGO:0021761380.030
development of primary sexual characteristicsGO:00451371070.029
cellular modified amino acid biosynthetic processGO:0042398180.029
oxoacid metabolic processGO:00434362900.029
positive regulation of metanephros developmentGO:007221620.029
positive regulation of phosphorylationGO:00423271770.029
nuclear transportGO:0051169490.029
organelle organizationGO:00069962660.029
multicellular organism growthGO:003526410.029
protein oligomerizationGO:00512591910.029
alpha amino acid biosynthetic processGO:1901607230.028
neurotransmitter secretionGO:0007269330.028
regulation of phosphorylationGO:00423252480.028
muscle system processGO:00030121150.028
organ formationGO:004864530.027
mesoderm formationGO:000170710.027
protein heterooligomerizationGO:0051291890.027
somatic stem cell maintenanceGO:003501920.027
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.027
cation transmembrane transportGO:00986552630.027
regulation of sequence specific dna binding transcription factor activityGO:0051090350.027
catabolic processGO:00090563510.026
naphthalene containing compound metabolic processGO:009042020.026
single organism organelle organizationGO:19025891800.026
signal transduction by phosphorylationGO:00230141440.026
organelle localizationGO:0051640550.026
regulation of neurotransmitter secretionGO:0046928190.026
rhombomere developmentGO:002154610.026
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010060.026
regulation of cell morphogenesisGO:0022604770.026
digestive system developmentGO:0055123410.026
protein targetingGO:0006605610.026
Human Mouse
tissue developmentGO:00098882520.026
circulatory system developmentGO:00723591340.026
action potentialGO:0001508540.026
regulation of cellular localizationGO:00603412630.025
male sex differentiationGO:0046661640.025
intracellular transportGO:00469071850.025
Human Mouse
regulation of protein complex assemblyGO:0043254330.025
positive regulation of amine transportGO:0051954260.024
regulation of cellular catabolic processGO:00313291010.024
regulation of protein localizationGO:0032880810.024
carboxylic acid metabolic processGO:00197522890.024
organic acid metabolic processGO:00060822920.024
cellular potassium ion transportGO:0071804720.024
maintenance of locationGO:0051235170.024
small gtpase mediated signal transductionGO:0007264360.024
negative regulation of gene expressionGO:00106291990.024
negative regulation of neurogenesisGO:0050768780.023
enzyme linked receptor protein signaling pathwayGO:00071671160.023
axis specificationGO:000979840.023
cellular component morphogenesisGO:00329891550.023
camp metabolic processGO:0046058630.023
regulation of tube sizeGO:0035150890.023
negative regulation of phosphorus metabolic processGO:0010563800.023
intracellular protein transportGO:0006886790.022
Human Mouse
organic substance catabolic processGO:19015753160.022
purine containing compound metabolic processGO:00725212530.022
gamete generationGO:00072761240.022
fluorene metabolic processGO:001891710.022
response to oxygen levelsGO:00704822650.022
cellular amino acid metabolic processGO:00065201070.022
oxidation reduction processGO:00551143040.022
g protein coupled receptor signaling pathwayGO:00071862420.022
nucleotide metabolic processGO:00091172790.021
potassium ion transmembrane transportGO:0071805710.021
response to cesium ionGO:001016420.021
single organism cellular localizationGO:19025801020.021
Human Mouse
macrophage chemotaxisGO:004824620.021
negative regulation of transportGO:00510511360.020
regulation of kinase activityGO:00435491170.020
response to oxidative stressGO:00069791860.020
positive regulation of nucleotide catabolic processGO:0030813530.020
positive regulation of intracellular signal transductionGO:19025331380.020
ribose phosphate metabolic processGO:00196932350.020
positive regulation of neurotransmitter secretionGO:000195690.020
regulation of dna metabolic processGO:0051052600.020
positive regulation of mitochondrion organizationGO:001082240.020
negative regulation of neuron differentiationGO:0045665620.019
regulation of phosphatidylinositol dephosphorylationGO:006030410.019
regulation of cardiac muscle contraction by calcium ion signalingGO:001088230.019
axonogenesisGO:0007409710.019
gonad developmentGO:00084061040.019
regulation of dendrite developmentGO:0050773590.019
aromatic compound catabolic processGO:00194391680.019
endocytosisGO:0006897840.019
dna templated transcription initiationGO:000635240.019
response to inorganic substanceGO:00100353770.019
ion transmembrane transportGO:00342203650.019
single organism biosynthetic processGO:00447113420.019
epibolyGO:009050420.019
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.019
regulation of cellular amine metabolic processGO:003323880.019
regulation of neuronal synaptic plasticityGO:0048168310.018
spermatogenesisGO:0007283990.018
positive regulation of apoptotic processGO:00430651540.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
neuron recognitionGO:000803890.018
positive regulation of transportGO:00510502450.018
organonitrogen compound biosynthetic processGO:19015661670.018
neuron apoptotic processGO:0051402880.018
single organism membrane organizationGO:0044802740.018
Human
regulation of calcium mediated signalingGO:005084880.018
negative regulation of cell developmentGO:0010721820.018
blood circulationGO:00080151830.018
cellular catabolic processGO:00442482950.018
mesoderm morphogenesisGO:004833210.018
arachidonic acid metabolic processGO:0019369200.017
cardiovascular system developmentGO:00723581340.017
positive regulation of neuron differentiationGO:00456661260.017
neuron projection guidanceGO:0097485240.017
positive regulation of nucleotide metabolic processGO:0045981910.017
intracellular receptor signaling pathwayGO:0030522350.017
diencephalon developmentGO:0021536210.017
development of primary male sexual characteristicsGO:0046546590.017
monocarboxylic acid transportGO:0015718520.017
positive regulation of phosphorus metabolic processGO:00105622620.017
heterocycle catabolic processGO:00467001670.017
gland developmentGO:00487321550.017
negative regulation of macromolecule metabolic processGO:00106052600.016
regulation of transferase activityGO:00513381230.016
regulation of catalytic activityGO:00507903040.016
mesenchymal to epithelial transitionGO:006023130.016
homeostatic processGO:00425923310.016
regulation of neuron projection developmentGO:00109751610.016
telencephalon developmentGO:0021537620.016
male gamete generationGO:0048232990.016
positive regulation of cell proliferationGO:00082842490.016
negative regulation of cell growth involved in cardiac muscle cell developmentGO:006105210.016
regulation of proteasomal protein catabolic processGO:006113640.016
negative regulation of muscle hypertrophyGO:001474130.016
spindle organizationGO:000705120.016
cellular protein complex assemblyGO:0043623440.016
monoamine transportGO:0015844430.016
epithelial cell migrationGO:0010631190.016
nucleocytoplasmic transportGO:0006913480.016
membrane fusionGO:0061025260.015
adult locomotory behaviorGO:000834440.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
regulation of nucleotide metabolic processGO:00061401170.015
positive regulation of smooth muscle cell proliferationGO:0048661510.015
positive regulation of immune system processGO:0002684900.015
positive regulation of molecular functionGO:00440932300.015
neuron fate commitmentGO:004866340.015
positive regulation of cellular amine metabolic processGO:003324030.015
circadian regulation of gene expressionGO:003292230.015
negative regulation of phosphate metabolic processGO:0045936800.015
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.015
regulation of protein transportGO:0051223680.015
heart processGO:0003015570.015
embryo developmentGO:0009790490.015
carbohydrate derivative metabolic processGO:19011353460.015
cellular macromolecular complex assemblyGO:0034622580.015
guanosine containing compound metabolic processGO:1901068740.015
positive regulation of cellular catabolic processGO:0031331710.015
regulation of cell maturationGO:190342930.015
cytoplasmic transportGO:00164821150.015
Mouse
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124120.015
regulation of exocytosisGO:0017157370.014
gtp metabolic processGO:0046039720.014
inorganic cation transmembrane transportGO:00986622020.014
halogenated hydrocarbon metabolic processGO:004219740.014
lipid localizationGO:0010876620.014
embryonic axis specificationGO:000057810.013
negative regulation of response to stimulusGO:00485851550.013
cell adhesionGO:00071551100.013
rna localizationGO:000640340.013
reproductive system developmentGO:00614581280.013
cyclic nucleotide biosynthetic processGO:0009190630.013
negative regulation of osteoblast differentiationGO:004566820.013
striated muscle cell developmentGO:0055002260.013
synaptic vesicle transportGO:0048489230.013
reproductive behaviorGO:0019098100.013
positive regulation of cell projection organizationGO:00313461110.013
regulation of cellular amino acid metabolic processGO:000652120.013
negative regulation of protein metabolic processGO:00512481140.013
mitotic spindle organizationGO:000705220.013
reproductive structure developmentGO:00486081280.013
anatomical structure formation involved in morphogenesisGO:0048646830.013
regulation of bmp signaling pathwayGO:003051020.013
negative regulation of rna biosynthetic processGO:19026791180.013
negative regulation of cell differentiationGO:0045596990.013
negative regulation of developmental processGO:00510931250.012
positive regulation of epithelial to mesenchymal transitionGO:001071820.012
purine nucleotide metabolic processGO:00061632290.012
biological adhesionGO:00226101100.012
cellular response to growth factor stimulusGO:00713631620.012
nucleoside phosphate metabolic processGO:00067532830.012
digestive tract developmentGO:0048565390.012
regulation of cellular ketone metabolic processGO:0010565270.012
establishment of protein localizationGO:00451841410.012
Human Mouse
regulation of sister chromatid segregationGO:003304510.012
regulation of nucleocytoplasmic transportGO:0046822280.012
protein autophosphorylationGO:0046777660.012
gliogenesisGO:0042063930.012
regulation of cellular protein metabolic processGO:00322682670.012
vesicle organizationGO:0016050290.012
cardiac conductionGO:006133720.012
chromosome separationGO:005130410.012
regulation of map kinase activityGO:0043405530.012
second messenger mediated signalingGO:0019932510.012
chromosome organizationGO:0051276360.012
peptidyl amino acid modificationGO:00181931260.012
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.012
growthGO:00400071650.012
carbohydrate derivative biosynthetic processGO:19011371240.012
negative regulation of alpha beta t cell activationGO:004663610.012
glial cell differentiationGO:0010001650.012
dorsal ventral axon guidanceGO:003356310.012
ras protein signal transductionGO:0007265290.012
fatty acid metabolic processGO:0006631990.012
response to cgmpGO:007030530.011
artery developmentGO:006084030.011
response to growth factorGO:00708481890.011
purine ribonucleoside metabolic processGO:00461281680.011
lipid storageGO:001991510.011
establishment of vesicle localizationGO:0051650310.011
regulation of embryonic developmentGO:004599520.011
macromolecule catabolic processGO:0009057580.011
neuroblast differentiationGO:001401610.011
metal ion homeostasisGO:00550651860.011
ribonucleotide metabolic processGO:00092592310.011
prepulse inhibitionGO:006013410.011
purine ribonucleotide metabolic processGO:00091502270.011
positive regulation of locomotionGO:00400171020.011
positive regulation of dna metabolic processGO:0051054390.011
cellular response to endogenous stimulusGO:00714953770.011
gtp catabolic processGO:0006184710.011
heart contractionGO:0060047570.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.011
metaphase anaphase transition of mitotic cell cycleGO:000709110.011
regulation of cellular response to stressGO:0080135490.011
regulation of cell projection organizationGO:00313441750.011
regulation of neuron apoptotic processGO:0043523830.011
mechanoreceptor differentiationGO:004249020.011
forebrain developmentGO:0030900980.011
germ cell migrationGO:000835410.011
positive regulation of mesenchymal cell proliferationGO:000205340.011
regulation of purine nucleotide catabolic processGO:0033121650.011
negative regulation of calcium ion importGO:009028120.011
dna replicationGO:0006260370.010
guanosine containing compound catabolic processGO:1901069710.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123950.010
nucleoside metabolic processGO:00091161790.010
nucleobase containing small molecule metabolic processGO:00550863160.010
cellular calcium ion homeostasisGO:00068741600.010
morphogenesis of embryonic epitheliumGO:001633130.010
positive regulation of catabolic processGO:0009896780.010
regulation of synapse organizationGO:0050807190.010
response to carbohydrateGO:00097431830.010
regulation of organelle organizationGO:0033043800.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.010
neurological system processGO:00508772190.010
long chain fatty acid metabolic processGO:0001676320.010
regulation of cyclic nucleotide biosynthetic processGO:0030802450.010
acid secretionGO:0046717480.010
regulation of stem cell differentiationGO:200073620.010

Pacs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.019
disease of anatomical entityDOID:700.019
disease of cellular proliferationDOID:1456600.010
cancerDOID:16200.010