Rattus norvegicus

125 known processes

Pfn1

profilin 1

Pfn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of actin filament polymerizationGO:003083850.918
cell cycleGO:00070491010.906
macromolecule localizationGO:00330362520.906
establishment of protein localizationGO:00451841410.818
cellular protein localizationGO:00346131220.791
cell migrationGO:00164771970.779
regulation of locomotionGO:00400121480.774
anatomical structure morphogenesisGO:00096532980.773
biological adhesionGO:00226101100.769
protein localizationGO:00081041910.752
dendritic spine developmentGO:0060996200.735
regulation of organelle organizationGO:0033043800.733
cellular component assemblyGO:00226073600.716
protein transportGO:00150311320.699
positive regulation of cellular component organizationGO:00511302000.683
neuron differentiationGO:00301823680.669
cell motilityGO:00488702020.665
regulation of cell migrationGO:00303341280.660
regulation of cellular component organizationGO:00511283680.651
actin nucleationGO:004501020.568
regulation of arp2 3 complex mediated actin nucleationGO:003431520.532
cellular component morphogenesisGO:00329891550.529
cellular component biogenesisGO:00440853680.527
reproductionGO:00000032450.514
cell projection organizationGO:00300303020.510
tissue developmentGO:00098882520.506
protein complex subunit organizationGO:00718223020.501
positive regulation of cellular component movementGO:00512721020.500
intracellular signal transductionGO:00355563140.497
intracellular transportGO:00469071850.493
positive regulation of cytoskeleton organizationGO:0051495260.484
cellular macromolecule localizationGO:00707271220.478
regulation of anatomical structure sizeGO:00900661350.471
Rat
polysaccharide metabolic processGO:0005976250.469
regulation of protein complex assemblyGO:0043254330.461
Rat
cytoskeleton organizationGO:00070101110.457
regulation of actin filament based processGO:0032970420.444
protein complex biogenesisGO:00702712630.440
Rat
localization of cellGO:00516742020.438
regulation of actin cytoskeleton organizationGO:0032956300.430
anatomical structure formation involved in morphogenesisGO:0048646830.413
neuron projection developmentGO:00311752730.410
actin filament based processGO:0030029860.408
regulation of actin polymerization or depolymerizationGO:0008064120.407
Rat
positive regulation of cell migrationGO:0030335960.406
cytoskeleton dependent cytokinesisGO:006164020.394
regulation of cellular component sizeGO:0032535510.391
Rat
organic substance catabolic processGO:19015753160.389
protein localization to organelleGO:0033365570.381
purine ribonucleoside triphosphate metabolic processGO:00092051400.380
organelle organizationGO:00069962660.375
single organism cellular localizationGO:19025801020.375
neural crest cell migrationGO:000175510.374
regulation of neurogenesisGO:00507672470.372
negative regulation of signalingGO:00230571570.365
actin cytoskeleton organizationGO:0030036730.361
regulation of neuron differentiationGO:00456642080.357
regulation of cell projection organizationGO:00313441750.352
cell projection morphogenesisGO:00488581230.352
head developmentGO:00603222470.351
circulatory system developmentGO:00723591340.349
locomotionGO:00400112370.348
regulation of cell motilityGO:20001451310.348
catabolic processGO:00090563510.347
macromolecular complex subunit organizationGO:00439333390.341
apoptotic processGO:00069153810.341
programmed cell deathGO:00125013920.334
establishment of cell polarityGO:003001060.329
regulation of cellular component biogenesisGO:0044087860.323
arp2 3 complex mediated actin nucleationGO:003431420.321
cell part morphogenesisGO:00329901230.317
cellular component movementGO:00069282480.311
purine nucleoside triphosphate catabolic processGO:00091461220.309
cell chemotaxisGO:0060326310.308
epithelium developmentGO:0060429960.303
purine containing compound catabolic processGO:00725231380.295
single organism organelle organizationGO:19025891800.295
divalent inorganic cation homeostasisGO:00725071650.280
nucleotide catabolic processGO:00091661390.278
regulation of cell morphogenesisGO:0022604770.276
regulation of programmed cell deathGO:00430673410.275
regulation of anatomical structure morphogenesisGO:00226031410.274
cell morphogenesis involved in differentiationGO:00009041190.274
nucleoside triphosphate catabolic processGO:00091431230.271
vesicle mediated transportGO:00161921810.266
cellular catabolic processGO:00442482950.264
response to other organismGO:00517072200.262
cell cycle processGO:0022402570.260
protein localization to membraneGO:0072657360.254
reproductive processGO:00224143720.244
intracellular protein transportGO:0006886790.238
behaviorGO:00076102050.238
regulation of cell differentiationGO:00455953200.237
regulation of multicellular organismal developmentGO:20000263760.235
cell projection assemblyGO:0030031210.231
regulation of actin filament lengthGO:0030832120.231
Rat
protein complex assemblyGO:00064612630.231
Rat
chemical homeostasisGO:00488782920.227
purine ribonucleotide catabolic processGO:00091541360.226
positive regulation of cellular component biogenesisGO:0044089550.225
cellular ion homeostasisGO:00068731840.224
energy derivation by oxidation of organic compoundsGO:0015980460.223
dendritic spine organizationGO:0097061120.223
regulation of cell developmentGO:00602842630.222
actin filament bundle organizationGO:0061572190.222
positive regulation of locomotionGO:00400171020.215
nucleobase containing compound catabolic processGO:00346551520.214
purine nucleotide catabolic processGO:00061951360.213
leukocyte migrationGO:0050900380.208
organophosphate catabolic processGO:00464341480.208
purine nucleoside catabolic processGO:00061521240.206
organophosphate metabolic processGO:00196373700.205
regulation of actin nucleationGO:005112520.205
single organism intracellular transportGO:19025821660.200
endocytosisGO:0006897840.199
multicellular organismal reproductive processGO:00486092330.198
negative regulation of cell communicationGO:00106481580.198
neuron developmentGO:00486662860.197
cell adhesionGO:00071551100.195
protein targetingGO:0006605610.195
g protein coupled receptor signaling pathwayGO:00071862420.191
multicellular organism reproductionGO:00325042330.189
actin polymerization or depolymerizationGO:0008154140.189
Rat
energy reserve metabolic processGO:0006112250.187
regulation of protein localizationGO:0032880810.184
actin filament organizationGO:0007015420.183
actin filament polymerizationGO:0030041110.181
Rat
cellular calcium ion homeostasisGO:00068741600.180
cellular metal ion homeostasisGO:00068751720.178
nucleotide metabolic processGO:00091172790.169
tube morphogenesisGO:0035239230.168
positive regulation of protein polymerizationGO:0032273100.165
regulation of cellular component movementGO:00512701500.164
guanosine containing compound catabolic processGO:1901069710.163
chemotaxisGO:0006935660.159
tube developmentGO:0035295890.157
gtp catabolic processGO:0006184710.155
regulation of actin filament depolymerizationGO:003083420.154
guanosine containing compound metabolic processGO:1901068740.149
aromatic compound catabolic processGO:00194391680.146
response to cytokineGO:00340972150.144
negative regulation of metabolic processGO:00098923310.142
muscle structure developmentGO:0061061870.140
establishment of protein localization to membraneGO:0090150160.136
cardiovascular system developmentGO:00723581340.135
angiogenesisGO:0001525530.135
positive regulation of signalingGO:00230562700.134
proteolysisGO:00065081750.134
regulation of protein polymerizationGO:0032271190.133
Rat
response to amino acidGO:0043200750.132
positive regulation of biosynthetic processGO:00098913190.130
generation of precursor metabolites and energyGO:0006091620.130
single organism reproductive processGO:00447022970.130
ribonucleotide catabolic processGO:00092611360.129
protein import into nucleusGO:0006606350.128
cellular homeostasisGO:00197252520.128
response to woundingGO:00096112540.128
translationGO:0006412350.126
cellular protein complex assemblyGO:0043623440.126
Rat
dendrite developmentGO:0016358720.123
central nervous system developmentGO:00074173110.122
purine ribonucleoside catabolic processGO:00461301240.122
purine nucleoside triphosphate metabolic processGO:00091441410.122
cellular nitrogen compound catabolic processGO:00442701630.122
nucleoside phosphate catabolic processGO:19012921400.121
cation homeostasisGO:00550801950.121
taxisGO:0042330670.120
protein importGO:0017038370.118
carbohydrate derivative catabolic processGO:19011361470.118
calcium ion homeostasisGO:00550741620.117
cell morphogenesisGO:00009021420.116
negative regulation of macromolecule metabolic processGO:00106052600.113
purine containing compound metabolic processGO:00725212530.112
positive regulation of endocytosisGO:0045807280.112
response to insulinGO:00328681330.110
nucleoside catabolic processGO:00091641260.110
positive regulation of cell deathGO:00109421840.109
startle responseGO:000196420.109
regulation of cellular protein metabolic processGO:00322682670.108
regulation of transcription from rna polymerase ii promoterGO:00063572340.107
cellular macromolecular complex assemblyGO:0034622580.106
Rat
establishment or maintenance of cell polarityGO:000716380.106
organonitrogen compound catabolic processGO:19015651790.106
response to carbohydrateGO:00097431830.104
heart developmentGO:0007507720.103
membrane organizationGO:0061024940.101
regulation of intracellular signal transductionGO:19025312180.101
axonogenesisGO:0007409710.101
positive regulation of cell motilityGO:2000147970.101
negative regulation of gene expressionGO:00106291990.101
immune system processGO:00023762040.100
cellular chemical homeostasisGO:00550822470.100
gland developmentGO:00487321550.099
cellular response to stressGO:00335542690.099
ribose phosphate metabolic processGO:00196932350.099
negative regulation of cellular component organizationGO:0051129830.099
positive regulation of developmental processGO:00510942830.099
regulation of cellular catabolic processGO:00313291010.098
regulation of neuron projection developmentGO:00109751610.096
glucan metabolic processGO:0044042230.095
response to oxygen levelsGO:00704822650.095
regulation of vesicle mediated transportGO:0060627810.094
organ regenerationGO:00311001010.092
regulation of signal transductionGO:00099663180.091
carbohydrate derivative metabolic processGO:19011353460.090
cell type specific apoptotic processGO:00972851340.089
muscle cell differentiationGO:0042692520.089
cell morphogenesis involved in neuron differentiationGO:00486671060.087
regulation of cell cycleGO:0051726730.087
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.086
nucleobase containing small molecule metabolic processGO:00550863160.086
ameboidal type cell migrationGO:0001667260.085
cellular response to cytokine stimulusGO:00713451270.083
negative regulation of cellular metabolic processGO:00313242810.083
sensory organ developmentGO:0007423740.082
glycosyl compound catabolic processGO:19016581260.082
actin filament depolymerizationGO:003004230.082
single organism membrane organizationGO:0044802740.080
regulation of cytoskeleton organizationGO:0051493490.080
small gtpase mediated signal transductionGO:0007264360.080
metal ion homeostasisGO:00550651860.080
positive regulation of organelle organizationGO:0010638480.079
purine ribonucleoside triphosphate catabolic processGO:00092071220.078
nucleoside metabolic processGO:00091161790.078
single organism catabolic processGO:00447122830.078
microtubule cytoskeleton organizationGO:0000226250.078
cytoplasmic transportGO:00164821150.075
nucleoside phosphate metabolic processGO:00067532830.074
positive regulation of macromolecule biosynthetic processGO:00105572470.073
neuron projection morphogenesisGO:00488121220.072
regulation of apoptotic processGO:00429813350.072
antigen processing and presentation of peptide antigen via mhc class iGO:000247410.072
meiotic cell cycle processGO:190304630.068
regulation of behaviorGO:0050795610.068
response to decreased oxygen levelsGO:00362932370.067
regulation of endocytosisGO:0030100420.067
cortical actin cytoskeleton organizationGO:003086620.067
metal ion transportGO:00300012890.067
positive regulation of response to stimulusGO:00485842850.067
heart morphogenesisGO:000300730.066
multi organism reproductive processGO:00447032620.065
regulation of phosphate metabolic processGO:00192203490.065
cytokinetic processGO:003250610.065
regulation of phosphorus metabolic processGO:00511743490.064
single organism carbohydrate metabolic processGO:00447231180.064
axon developmentGO:0061564960.064
response to inorganic substanceGO:00100353770.064
regulation of immune system processGO:00026821230.062
cellular divalent inorganic cation homeostasisGO:00725031620.061
sexual reproductionGO:00199531480.061
positive regulation of apoptotic processGO:00430651540.061
ras protein signal transductionGO:0007265290.061
regulation of hydrolase activityGO:00513361430.060
protein targeting to nucleusGO:0044744350.060
cellular response to insulin stimulusGO:0032869810.060
negative regulation of phosphate metabolic processGO:0045936800.060
cytokinesisGO:000091050.059
smad protein complex assemblyGO:000718310.059
positive regulation of cytosolic calcium ion concentrationGO:00072041220.059
regulation of homeostatic processGO:00328441010.059
response to extracellular stimulusGO:00099913800.059
response to glucocorticoidGO:00513842230.058
cellular cation homeostasisGO:00300031800.058
ribonucleoside catabolic processGO:00424541260.057
negative regulation of response to stimulusGO:00485851550.057
macromolecular complex assemblyGO:00650032730.057
Rat
cellular response to organonitrogen compoundGO:00714171970.057
negative regulation of cell deathGO:00605482290.056
ubiquitin dependent protein catabolic processGO:0006511140.056
regulation of response to external stimulusGO:00321011060.056
ribonucleoside metabolic processGO:00091191740.056
cellular polysaccharide metabolic processGO:0044264230.055
regulation of dna metabolic processGO:0051052600.055
leukocyte chemotaxisGO:0030595220.055
protein polymerizationGO:0051258220.054
Rat
ion homeostasisGO:00508012120.054
response to hypoxiaGO:00016662310.053
homeostatic processGO:00425923310.053
regulation of purine nucleotide catabolic processGO:0033121650.053
gastrulationGO:000736920.053
microtubule based processGO:0007017360.052
positive regulation of dna metabolic processGO:0051054390.050
response to corticosteroidGO:00319602350.050
morphogenesis of an epitheliumGO:0002009200.048
skeletal muscle fiber adaptationGO:004350310.048
positive regulation of programmed cell deathGO:00430681570.047
receptor metabolic processGO:0043112180.047
agingGO:00075682410.047
fertilizationGO:000956630.047
positive regulation of gene expressionGO:00106282440.047
cellular response to peptide hormone stimulusGO:00713751200.046
purine ribonucleotide metabolic processGO:00091502270.046
negative regulation of signal transductionGO:0009968830.045
purine ribonucleoside metabolic processGO:00461281680.045
erbb signaling pathwayGO:0038127230.044
regulation of metal ion transportGO:00109591180.044
carbohydrate metabolic processGO:00059751300.044
tissue morphogenesisGO:0048729220.044
macromolecule catabolic processGO:0009057580.044
negative regulation of protein metabolic processGO:00512481140.044
heterocycle catabolic processGO:00467001670.044
cation transportGO:00068123820.043
endomembrane system organizationGO:0010256480.043
regulation of cellular localizationGO:00603412630.043
oxoacid metabolic processGO:00434362900.042
regulation of molecular functionGO:00650093980.041
regulation of transcription dna templatedGO:00063553740.041
positive regulation of nucleotide catabolic processGO:0030813530.041
cell cell signalingGO:00072673350.040
regulation of dendrite developmentGO:0050773590.040
regulation of nervous system developmentGO:00519602640.040
secretionGO:00469033070.040
modification dependent protein catabolic processGO:0019941140.040
oxidation reduction processGO:00551143040.039
rna metabolic processGO:00160704060.039
regulation of translationGO:0006417270.038
secretion by cellGO:00329402480.038
brain developmentGO:00074202470.038
response to peptide hormoneGO:00434342780.038
positive regulation of cell communicationGO:00106472710.037
positive regulation of lipid biosynthetic processGO:0046889250.037
regulation of nucleoside metabolic processGO:0009118660.037
cellular response to external stimulusGO:00714961180.037
mapk cascadeGO:00001651400.037
positive regulation of phosphate metabolic processGO:00459372620.037
regulation of protein metabolic processGO:00512462890.037
cell cell junction organizationGO:0045216200.036
carbohydrate derivative biosynthetic processGO:19011371240.036
regulation of catabolic processGO:00098941130.036
ribonucleoside triphosphate metabolic processGO:00091991410.036
regulation of response to stressGO:00801341260.036
receptor internalizationGO:0031623140.036
cell cycle checkpointGO:000007520.036
regulation of phagocytosisGO:0050764130.036
positive regulation of leukocyte migrationGO:0002687210.036
regulation of catalytic activityGO:00507903040.035
response to external biotic stimulusGO:00432072210.035
defense responseGO:00069521940.035
single organism nuclear importGO:1902593350.034
glucan biosynthetic processGO:0009250150.034
regulation of dendritic spine morphogenesisGO:006100160.034
spermatogenesisGO:0007283990.034
cellular response to endogenous stimulusGO:00714953770.034
circadian rhythmGO:0007623880.034
enzyme linked receptor protein signaling pathwayGO:00071671160.034
blood vessel morphogenesisGO:0048514580.034
response to nutrient levelsGO:00316673700.034
embryonic morphogenesisGO:0048598140.033
carboxylic acid metabolic processGO:00197522890.033
negative regulation of arp2 3 complex mediated actin nucleationGO:003431610.033
transmembrane transportGO:00550854120.032
regulation of meiotic cell cycleGO:005144530.032
regulation of ion transportGO:00432692450.032
nucleic acid templated transcriptionGO:00976593790.032
plasma membrane organizationGO:0007009170.032
male gamete generationGO:0048232990.031
organelle fusionGO:0048284170.031
regulation of synaptic transmissionGO:00508041410.031
cellular response to hormone stimulusGO:00328702470.031
organic cyclic compound catabolic processGO:19013611750.031
amine metabolic processGO:0009308380.031
embryo developmentGO:0009790490.031
response to glucoseGO:00097491360.030
nuclear transportGO:0051169490.030
behavioral response to ethanolGO:004814910.030
ion transmembrane transportGO:00342203650.030
response to alkaloidGO:00432791320.030
negative regulation of nucleic acid templated transcriptionGO:19035071170.030
striated muscle cell differentiationGO:0051146390.030
regulation of purine nucleotide metabolic processGO:19005421150.030
single organism cell adhesionGO:0098602460.030
cellular amino acid metabolic processGO:00065201070.029
protein localization to nucleusGO:0034504390.029
negative regulation of apoptotic processGO:00430661810.029
purine nucleoside metabolic processGO:00422781690.029
positive regulation of cellular biosynthetic processGO:00313282950.029
cellular response to oxygen containing compoundGO:19017013860.028
response to hexoseGO:00097461440.028
ribonucleotide metabolic processGO:00092592310.028
protein oligomerizationGO:00512591910.028
epidermal growth factor receptor signaling pathwayGO:0007173230.028
regulation of phosphorylationGO:00423252480.028
regulation of nucleotide catabolic processGO:0030811650.028
gamete generationGO:00072761240.028
response to monosaccharideGO:00342841590.028
transcription dna templatedGO:00063513770.028
single fertilizationGO:000733830.028
neuromuscular processGO:005090520.027
positive regulation of protein depolymerizationGO:190188130.027
response to oxidative stressGO:00069791860.027
striated muscle tissue developmentGO:0014706580.026
glycosyl compound metabolic processGO:19016571820.026
dna metabolic processGO:0006259960.026
eye developmentGO:0001654500.026
protein phosphorylationGO:00064683450.026
negative regulation of developmental processGO:00510931250.026
neural crest cell differentiationGO:001403320.025
cellular ketone metabolic processGO:0042180510.025
t cell homeostasisGO:004302920.025
negative regulation of programmed cell deathGO:00430691830.025
negative regulation of cell differentiationGO:0045596990.025
nucleocytoplasmic transportGO:0006913480.025
neural tube formationGO:000184110.025
negative regulation of multicellular organismal processGO:00512412030.024
leukocyte activationGO:0045321760.024
positive regulation of hydrolase activityGO:0051345860.024
positive regulation of transportGO:00510502450.024
divalent metal ion transportGO:00708381320.024
immune responseGO:00069551040.024
synaptic transmissionGO:00072682350.024
cellular response to peptideGO:19016531330.023
leukocyte proliferationGO:0070661290.023
transcription from rna polymerase ii promoterGO:00063662520.023
positive regulation of cell morphogenesis involved in differentiationGO:0010770410.023
positive regulation of cell proliferationGO:00082842490.023
regulation of receptor mediated endocytosisGO:0048259170.022
negative regulation of rna metabolic processGO:00512531230.022
regulation of nucleic acid templated transcriptionGO:19035063800.022
cardiocyte differentiationGO:0035051220.022
cellular amine metabolic processGO:0044106380.022
response to lithium ionGO:0010226280.022
muscle system processGO:00030121150.022
neural crest cell developmentGO:001403220.022
digestive tract developmentGO:0048565390.022
regulation of cell sizeGO:0008361370.022
phospholipid biosynthetic processGO:0008654290.022
morphogenesis of embryonic epitheliumGO:001633130.022
transmission of nerve impulseGO:0019226420.022
cell substrate adhesionGO:0031589290.021
blood vessel developmentGO:0001568690.021
positive regulation of protein oligomerizationGO:003246110.021
calcium ion transportGO:00068161310.021
positive regulation of intracellular signal transductionGO:19025331380.021
central nervous system neuron axonogenesisGO:002195510.021
response to metal ionGO:00100382530.021
cellular response to abiotic stimulusGO:0071214850.021
regenerationGO:00310991630.021
regulation of leukocyte migrationGO:0002685240.021
negative regulation of cellular protein metabolic processGO:00322691060.020
endoplasmic reticulum organizationGO:000702910.020
regulation of cellular amine metabolic processGO:003323880.020
blood circulationGO:00080151830.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
polysaccharide biosynthetic processGO:0000271160.020
regulation of protein depolymerizationGO:190187980.020
actin filament branchingGO:009013510.020
wound healingGO:00420601220.020
organic anion transportGO:00157111320.020
positive regulation of phosphorus metabolic processGO:00105622620.020
lipid metabolic processGO:00066292830.020
negative regulation of peptidase activityGO:0010466380.019
response to growth factorGO:00708481890.019
posttranscriptional regulation of gene expressionGO:0010608370.019
circadian regulation of gene expressionGO:003292230.019
positive regulation of chemotaxisGO:0050921230.019
negative regulation of transportGO:00510511360.019
response to ethanolGO:00454711620.019
regulation of nucleotide metabolic processGO:00061401170.019
t cell proliferationGO:0042098190.019
regulation of cellular amino acid metabolic processGO:000652120.018
somatic stem cell divisionGO:004810320.018
regulation of hormone levelsGO:00108171870.018
mitotic spindle organizationGO:000705220.018
gliogenesisGO:0042063930.018
regulation of rna biosynthetic processGO:20011413810.018
camera type eye developmentGO:0043010480.018
regulation of lipid biosynthetic processGO:0046890380.017
organelle localizationGO:0051640550.017
response to axon injuryGO:0048678590.017
regulation of cell adhesionGO:0030155520.017
dendrite morphogenesisGO:0048813430.017
sequestering of calcium ionGO:005120880.017
cytosolic calcium ion homeostasisGO:00514801400.017
response to estradiolGO:00323551640.017
rhythmic processGO:00485111560.017
mitotic cell cycleGO:0000278490.017
hematopoietic progenitor cell differentiationGO:000224420.017
regulation of ion homeostasisGO:2000021630.017
negative regulation of catalytic activityGO:00430861030.017
regulation of cell substrate adhesionGO:0010810180.017
growthGO:00400071650.017
epithelial cell differentiationGO:0030855710.017
muscle tissue developmentGO:0060537580.016

Pfn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.090
disease of anatomical entityDOID:700.090
sensory system diseaseDOID:005015500.071
cancerDOID:16200.063
disease of cellular proliferationDOID:1456600.063
musculoskeletal system diseaseDOID:1700.046
organ system cancerDOID:005068600.032
gastrointestinal system cancerDOID:311900.021
bone diseaseDOID:008000100.018
connective tissue diseaseDOID:6500.018
liver carcinomaDOID:68600.016
hepatocellular carcinomaDOID:68400.016
liver cancerDOID:357100.016