IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Uqcrc2

ubiquinol cytochrome c reductase core protein 2

(Aliases: MGC94368)

RGD: 1359150
Entrez: 293448
Ensembl: ENSRNOG00000036742
UniProtKB: P32551

Process Predictions
Disease Predictions

Uqcrc2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
acetyl coa biosynthetic process from pyruvate	GO:0006086	5	0.923
atp synthesis coupled electron transport	GO:0042773	2	0.772	Yeast
dicarboxylic acid metabolic process	GO:0043648	42	0.523
cofactor biosynthetic process	GO:0051188	28	0.489
sulfur compound biosynthetic process	GO:0044272	19	0.482
acetyl coa biosynthetic process	GO:0006085	6	0.413
oxidative phosphorylation	GO:0006119	4	0.407	Yeast
hydrogen peroxide metabolic process	GO:0042743	13	0.364
nucleobase containing small molecule metabolic process	GO:0055086	316	0.306	Yeast
acyl coa metabolic process	GO:0006637	28	0.300
organic acid metabolic process	GO:0006082	292	0.285
oxoacid metabolic process	GO:0043436	290	0.275
cofactor metabolic process	GO:0051186	95	0.272
coenzyme metabolic process	GO:0006732	86	0.237
organophosphate metabolic process	GO:0019637	370	0.227	Yeast
single organism biosynthetic process	GO:0044711	342	0.222
carboxylic acid metabolic process	GO:0019752	289	0.217
atp metabolic process	GO:0046034	72	0.201	Yeast
monocarboxylic acid metabolic process	GO:0032787	152	0.184
growth	GO:0040007	165	0.176
acyl coa biosynthetic process	GO:0071616	7	0.166
apoptotic mitochondrial changes	GO:0008637	10	0.155
coenzyme biosynthetic process	GO:0009108	22	0.151
generation of precursor metabolites and energy	GO:0006091	62	0.150	Yeast
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.118	Yeast
oxidation reduction process	GO:0055114	304	0.115	Yeast
ribonucleoside metabolic process	GO:0009119	174	0.110	Yeast
sulfur compound metabolic process	GO:0006790	70	0.107
neurotransmitter uptake	GO:0001504	3	0.097
nucleotide metabolic process	GO:0009117	279	0.094	Yeast
energy derivation by oxidation of organic compounds	GO:0015980	46	0.085	Yeast
regulation of membrane potential	GO:0042391	110	0.084
glial cell apoptotic process	GO:0034349	8	0.076
thioester metabolic process	GO:0035383	28	0.075
regulation of nucleic acid templated transcription	GO:1903506	380	0.074
positive regulation of cell proliferation	GO:0008284	249	0.071
cellular respiration	GO:0045333	21	0.064	Yeast
isocitrate metabolic process	GO:0006102	5	0.062
aging	GO:0007568	241	0.061
anion transport	GO:0006820	178	0.057
electron transport chain	GO:0022900	5	0.057	Yeast
transmembrane transport	GO:0055085	412	0.055	Yeast
adenine nucleotide transport	GO:0051503	2	0.055
regulation of rna metabolic process	GO:0051252	391	0.054
purine nucleoside metabolic process	GO:0042278	169	0.054	Yeast
pyruvate metabolic process	GO:0006090	27	0.053
regulation of cell proliferation	GO:0042127	359	0.052
ribonucleoside monophosphate metabolic process	GO:0009161	88	0.051	Yeast
nucleoside metabolic process	GO:0009116	179	0.050	Yeast
programmed cell death	GO:0012501	392	0.049
regulation of apoptotic process	GO:0042981	335	0.046
centrosome organization	GO:0051297	1	0.045
negative regulation of cellular metabolic process	GO:0031324	281	0.044
nucleoside triphosphate metabolic process	GO:0009141	144	0.043	Yeast
nucleoside monophosphate metabolic process	GO:0009123	93	0.042	Yeast
malate metabolic process	GO:0006108	5	0.042
cell redox homeostasis	GO:0045454	1	0.041
thioester biosynthetic process	GO:0035384	7	0.041
fatty acid metabolic process	GO:0006631	99	0.041
mitochondrion organization	GO:0007005	35	0.039
response to oxidative stress	GO:0006979	186	0.039
aerobic respiration	GO:0009060	13	0.039	Yeast
purine containing compound metabolic process	GO:0072521	253	0.038	Yeast
single organism intracellular transport	GO:1902582	166	0.037
negative regulation of macromolecule metabolic process	GO:0010605	260	0.037
carbohydrate derivative metabolic process	GO:1901135	346	0.036	Yeast
l glutamate import	GO:0051938	2	0.036
transcription dna templated	GO:0006351	377	0.035
synaptic vesicle transport	GO:0048489	23	0.034
regulation of immune system process	GO:0002682	123	0.034
response to nutrient levels	GO:0031667	370	0.033
organelle organization	GO:0006996	266	0.033
regulation of transcription dna templated	GO:0006355	374	0.033
nucleoside phosphate metabolic process	GO:0006753	283	0.032	Yeast
regulation of cellular component organization	GO:0051128	368	0.031
regulation of rna biosynthetic process	GO:2001141	381	0.031
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.031
nitrogen compound transport	GO:0071705	229	0.030
response to interleukin 1	GO:0070555	55	0.029
regulation of programmed cell death	GO:0043067	341	0.029
reproductive process	GO:0022414	372	0.029
single organism reproductive process	GO:0044702	297	0.029
negative regulation of cellular biosynthetic process	GO:0031327	161	0.029
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.028	Yeast
negative regulation of transcription dna templated	GO:0045892	116	0.027
rna metabolic process	GO:0016070	406	0.027
cell cell signaling	GO:0007267	335	0.025
cellular response to oxygen containing compound	GO:1901701	386	0.025
negative regulation of hydrogen peroxide biosynthetic process	GO:0010730	2	0.025
macromolecular complex subunit organization	GO:0043933	339	0.025
negative regulation of cell death	GO:0060548	229	0.025
leukocyte activation	GO:0045321	76	0.025
regulation of protein metabolic process	GO:0051246	289	0.024
amino acid transport	GO:0006865	70	0.024
negative regulation of metabolic process	GO:0009892	331	0.023
purine nucleotide transport	GO:0015865	3	0.023
positive regulation of cellular biosynthetic process	GO:0031328	295	0.023
multicellular organismal reproductive process	GO:0048609	233	0.022
protein complex subunit organization	GO:0071822	302	0.022
positive regulation of transport	GO:0051050	245	0.022
negative regulation of biosynthetic process	GO:0009890	168	0.021
intracellular transport	GO:0046907	185	0.021
regulation of ion transport	GO:0043269	245	0.021
response to extracellular stimulus	GO:0009991	380	0.021
positive regulation of atp biosynthetic process	GO:2001171	2	0.021
regulation of phosphate metabolic process	GO:0019220	349	0.021
small molecule biosynthetic process	GO:0044283	124	0.021
purine nucleotide metabolic process	GO:0006163	229	0.021	Yeast
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	141	0.021
circadian regulation of gene expression	GO:0032922	3	0.020
mitochondrial calcium ion homeostasis	GO:0051560	3	0.020
multi organism reproductive process	GO:0044703	262	0.020
reproduction	GO:0000003	245	0.019
positive regulation of biosynthetic process	GO:0009891	319	0.019
regulation of atp biosynthetic process	GO:2001169	2	0.019
oxidoreduction coenzyme metabolic process	GO:0006733	31	0.019
heterocycle catabolic process	GO:0046700	167	0.018
2 oxoglutarate metabolic process	GO:0006103	6	0.018
cellular amino acid metabolic process	GO:0006520	107	0.018
negative regulation of programmed cell death	GO:0043069	183	0.018
organophosphate biosynthetic process	GO:0090407	143	0.018
multicellular organism reproduction	GO:0032504	233	0.018
positive regulation of ion transport	GO:0043270	94	0.018
alternative mrna splicing via spliceosome	GO:0000380	4	0.018
response to nutrient	GO:0007584	248	0.017
lipid storage	GO:0019915	1	0.017
nucleic acid templated transcription	GO:0097659	379	0.017
regulation of molecular function	GO:0065009	398	0.017
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.017
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.017	Yeast
cellular response to hormone stimulus	GO:0032870	247	0.017
positive regulation of molecular function	GO:0044093	230	0.017
response to toxic substance	GO:0009636	133	0.017
tetrapyrrole biosynthetic process	GO:0033014	7	0.017
cellular ketone metabolic process	GO:0042180	51	0.017
ion transmembrane transport	GO:0034220	365	0.017	Yeast
regulation of cellular protein metabolic process	GO:0032268	267	0.016
reactive oxygen species metabolic process	GO:0072593	37	0.016
pigment biosynthetic process	GO:0046148	4	0.016
organic substance catabolic process	GO:1901575	316	0.015
regulation of phosphorus metabolic process	GO:0051174	349	0.015
apoptotic process	GO:0006915	381	0.015
cellular amine metabolic process	GO:0044106	38	0.015
central nervous system development	GO:0007417	311	0.015
amine metabolic process	GO:0009308	38	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.015	Yeast
developmental growth	GO:0048589	100	0.014
single organism organelle organization	GO:1902589	180	0.014
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
peptidyl amino acid modification	GO:0018193	126	0.014
negative regulation of gene expression	GO:0010629	199	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.014
response to hypoxia	GO:0001666	231	0.014
synaptic growth at neuromuscular junction	GO:0051124	1	0.014
organic anion transport	GO:0015711	132	0.014
metal ion transport	GO:0030001	289	0.014
vesicle mediated transport	GO:0016192	181	0.014
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	GO:2001240	3	0.013
dicarboxylic acid transport	GO:0006835	34	0.013
purine ribonucleotide metabolic process	GO:0009150	227	0.013	Yeast
purine ribonucleotide biosynthetic process	GO:0009152	81	0.013
developmental process involved in reproduction	GO:0003006	159	0.013
cellular calcium ion homeostasis	GO:0006874	160	0.013
regulation of transferase activity	GO:0051338	123	0.013
oxaloacetate metabolic process	GO:0006107	6	0.013
cardiovascular system development	GO:0072358	134	0.013
response to lipopolysaccharide	GO:0032496	191	0.012
cellular homeostasis	GO:0019725	252	0.012
response to decreased oxygen levels	GO:0036293	237	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
regulation of phosphorylation	GO:0042325	248	0.012
mitotic spindle organization	GO:0007052	2	0.012
tricarboxylic acid cycle	GO:0006099	11	0.012
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.012
regulation of reactive oxygen species metabolic process	GO:2000377	26	0.012
single organism membrane organization	GO:0044802	74	0.012
ribose phosphate metabolic process	GO:0019693	235	0.012	Yeast
regulation of kinase activity	GO:0043549	117	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.012
spindle organization	GO:0007051	2	0.012
negative regulation of cellular protein metabolic process	GO:0032269	106	0.011
cell morphogenesis	GO:0000902	142	0.011
cellular component biogenesis	GO:0044085	368	0.011
negative regulation of protein metabolic process	GO:0051248	114	0.011
single organism catabolic process	GO:0044712	283	0.011
pyridine nucleotide metabolic process	GO:0019362	28	0.011
sexual reproduction	GO:0019953	148	0.011
spermatogenesis	GO:0007283	99	0.011
regulation of meiotic cell cycle	GO:0051445	3	0.011
adp biosynthetic process	GO:0006172	8	0.011
programmed necrotic cell death	GO:0097300	2	0.011
response to acid chemical	GO:0001101	222	0.011
homeostatic process	GO:0042592	331	0.011
heme biosynthetic process	GO:0006783	4	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
positive regulation of rna metabolic process	GO:0051254	203	0.010
response to hydrogen peroxide	GO:0042542	89	0.010
cellular response to peptide	GO:1901653	133	0.010
proteolysis	GO:0006508	175	0.010
cellular response to stress	GO:0033554	269	0.010
negative regulation of phosphorus metabolic process	GO:0010563	80	0.010
cellular catabolic process	GO:0044248	295	0.010

Uqcrc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.438
organic acidemia	DOID:0060159	0.438
amino acid metabolic disorder	DOID:9252	0.438
disease of metabolism	DOID:0014667	0.438
nervous system disease	DOID:863	0.024
sensory system disease	DOID:0050155	0.024
eye and adnexa disease	DOID:1492	0.024
eye disease	DOID:5614	0.024
disease of anatomical entity	DOID:7	0.024
retinal degeneration	DOID:8466	0.024
retinal disease	DOID:5679	0.024
muscle tissue disease	DOID:66	0.019
muscular dystrophy	DOID:9884	0.019
muscular disease	DOID:0080000	0.019
myopathy	DOID:423	0.019
musculoskeletal system disease	DOID:17	0.019
maple syrup urine disease	DOID:9269	0.017
retinitis pigmentosa	DOID:10584	0.017

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